Detailed information for compound 1413450

Basic information

Technical information
  • TDR Targets ID: 1413450
  • Name: 2-[[4-[[2-(2-methylphenoxy)acetyl]amino]benzo yl]amino]benzoic acid
  • MW: 404.415 | Formula: C23H20N2O5
  • H donors: 3 H acceptors: 4 LogP: 4.07 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)C(=O)Nc1ccccc1C(=O)O)COc1ccccc1C
  • InChi: 1S/C23H20N2O5/c1-15-6-2-5-9-20(15)30-14-21(26)24-17-12-10-16(11-13-17)22(27)25-19-8-4-3-7-18(19)23(28)29/h2-13H,14H2,1H3,(H,24,26)(H,25,27)(H,28,29)
  • InChiKey: MUCRPUNCHJSUSG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[[[4-[[2-(2-methylphenoxy)-1-oxoethyl]amino]phenyl]-oxomethyl]amino]benzoic acid
  • 2-[[4-[2-(2-methylphenoxy)ethanoylamino]phenyl]carbonylamino]benzoic acid
  • STK299578

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens K(lysine) acetyltransferase 2A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Theileria parva histone acetyltransferase Gcn5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum hypothetical protein Get druggable targets OG5_127781 All targets in OG5_127781
Toxoplasma gondii histone lysine acetyltransferase GCN5-A Get druggable targets OG5_127781 All targets in OG5_127781
Toxoplasma gondii histone lysine acetyltransferase GCN5-B Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica acetyltransferase, GNAT family Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma japonicum ko:K06062 p300/CBP-associated factor, putative Get druggable targets OG5_127781 All targets in OG5_127781
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium hominis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium berghei histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium knowlesi histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium parvum GCN5 like acetylase + bromodomain Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum Bromodomain containing protein, related Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis bromodomain-containing protein, putative Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium falciparum histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium vivax histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Giardia lamblia Histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium yoelii histone acetyltransferase GCN5-related Get druggable targets OG5_127781 All targets in OG5_127781
Brugia malayi acetyltransferase, GNAT family protein Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Babesia bovis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0057 0.1536
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0084 0.0268 0.2969
Trichomonas vaginalis ran, putative 0.0023 0.0057 0.1536
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.001 0.0012 0.0063
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0059 0.031
Mycobacterium leprae conserved hypothetical protein 0.0078 0.0249 0.0248
Onchocerca volvulus 0.0123 0.0403 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0249 0.2188
Echinococcus granulosus peptide allatostatin:somatostatin 0.0024 0.0059 0.031
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0024 0.0059 0.031
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0024 0.0059 0.031
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0007 0.0001 0.0015
Echinococcus multilocularis cGMP dependent protein kinase 1 0.001 0.0014 0.0072
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0017 0.0456
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0017 0.0036 0.0401
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0029 0.0154
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0126
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0017 0.0456
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.001 0.0012 0.0294
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0081 0.0259 0.6943
Echinococcus multilocularis serotonin receptor 0.0024 0.0059 0.031
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0017 0.0456
Echinococcus multilocularis beta LACTamase domain containing family member 0.0078 0.0249 0.1314
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.001 0.0012 0.0294
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0023 0.0057 0.1542
Onchocerca volvulus 0.0011 0.0017 0.0422
Onchocerca volvulus Putative organic anion transporter 0.0123 0.0403 1
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0081 0.0259 0.1366
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Giardia lamblia Cysteinyl-tRNA synthetase 0.0042 0.0123 0.4768
Brugia malayi hypothetical protein 0.0024 0.0059 0.0651
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0014 0.0159
Mycobacterium tuberculosis Probable esterase LipL 0.0078 0.0249 0.0237
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0014 0.0159
Entamoeba histolytica P-glycoprotein-2 0.0011 0.0017 0.0456
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0011 0.0017 0.0422
Brugia malayi Thioredoxin reductase 0.0067 0.0209 0.2311
Echinococcus multilocularis snurportin 1 0.0335 0.1138 0.6005
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0014 0.0076
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0086 0.2306
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0007 0.0003 0.0083
Mycobacterium tuberculosis Conserved protein 0.0078 0.0249 0.0237
Echinococcus granulosus neuropeptide receptor A26 0.0024 0.0059 0.031
Brugia malayi secreted modular calcium-binding protein 1 0.0084 0.0268 0.2969
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0055 0.0043
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0055 0.0053
Loa Loa (eye worm) hypothetical protein 0.0123 0.0403 0.3546
Brugia malayi hypothetical protein 0.0024 0.0059 0.0651
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0029 0.0322
Trypanosoma cruzi cAMP binding protein, putative 0.001 0.0012 0.0294
Onchocerca volvulus 0.0024 0.0059 0.1457
Schistosoma mansoni follistatin 0.0084 0.0268 0.1416
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0014 0.0076
Onchocerca volvulus 0.0011 0.0014 0.0356
Brugia malayi putative neuropeptide receptor 0.0024 0.0059 0.0651
Onchocerca volvulus 0.0024 0.0059 0.1457
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0001 0.0036
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0055 0.0288
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0059 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0373 1
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0169 0.4542
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0014 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0036
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0001 0.0036
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.0029 0.0154
Trypanosoma brucei cAMP binding protein, putative 0.001 0.0012 0.0319
Schistosoma mansoni neuropeptide receptor 0.0024 0.0059 0.031
Leishmania major GTP-binding protein, putative 0.0023 0.0057 0.1536
Echinococcus multilocularis neuropeptide receptor A26 0.0024 0.0059 0.031
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0024 0.0059 0.031
Brugia malayi N-terminal motif family protein 0.001 0.0012 0.0131
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.001 0.0012 0.0319
Loa Loa (eye worm) cysteinyl tRNA synthetase 1 0.0042 0.0123 0.1085
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0014 0.0126
Loa Loa (eye worm) hypothetical protein 0.0078 0.0249 0.2188
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Schistosoma mansoni importin beta-1 0.0031 0.0086 0.0454
Plasmodium vivax importin-beta 2, putative 0.0031 0.0086 0.2306
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0042 0.0123 0.0652
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0055 0.1354
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0078 0.0249 0.2755
Schistosoma mansoni multidrug resistance protein 0.0011 0.0017 0.009
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0017 0.0456
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0055 0.0043
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.001 0.0012 0.0319
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.001 0.0012 0.0319
Plasmodium falciparum cysteine--tRNA ligase 0.0042 0.0123 0.3311
Brugia malayi hypothetical protein 0.0024 0.0059 0.0651
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0146
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0014 0.0076
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0059 0.031
Echinococcus granulosus cGMP dependent protein kinase 1 0.001 0.0014 0.0072
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0055 0.0043
Brugia malayi G-protein coupled receptor 0.0024 0.0059 0.0651
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0014 0.0159
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0249 0.1314
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.001 0.0012 0.0063
Trichomonas vaginalis adenylate cyclase type, putative 0.0007 0.0001 0.0036
Brugia malayi Serotonin receptor 0.0024 0.0059 0.0651
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0023 0.0057 0.0046
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0033 0.0174
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.008 0.0888
Loa Loa (eye worm) AGC/PKG protein kinase 0.001 0.0014 0.012
Brugia malayi hypothetical protein 0.0024 0.0059 0.0651
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0023 0.0057 0.1542
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0169 0.4542
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.001 0.0012 0.0319
Loa Loa (eye worm) agrin synaptic family protein 0.0084 0.0268 0.2357
Onchocerca volvulus 0.0078 0.0249 0.617
Brugia malayi ABC transporter family protein 0.0011 0.0017 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0249 0.617
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0014 0.0076
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.2894 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0059 0.031
Treponema pallidum NADH oxidase 0.0023 0.0057 0.4088
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0017 0.009
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0007 0.0001 0.0036
Echinococcus multilocularis follistatin 0.0084 0.0268 0.1416
Brugia malayi Dopamine receptor protein 1 0.0024 0.0059 0.0651
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0023 0.0057 0.1542
Echinococcus multilocularis transcription factor btf3 0.0114 0.0373 0.1968
Echinococcus multilocularis neuropeptide FF receptor 2 0.0024 0.0059 0.031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0059 0.031
Onchocerca volvulus 0.001 0.0012 0.0294
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0141 0.3774
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Brugia malayi cysteinyl tRNA synthetase protein 1 0.0042 0.0123 0.1366
Echinococcus granulosus intermediate filament protein 0.0055 0.0169 0.0895
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0055 0.0169 0.4198
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0024 0.0059 0.0517
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Plasmodium vivax basic transcription factor 3b, putative 0.0114 0.0373 1
Loa Loa (eye worm) hypothetical protein 0.0123 0.0403 0.3546
Loa Loa (eye worm) hypothetical protein 0.0054 0.0166 0.1459
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0005 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0036
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0024 0.0059 0.031
Trypanosoma brucei trypanothione reductase 0.0067 0.0209 0.56
Loa Loa (eye worm) hypothetical protein 0.0055 0.0169 0.149
Loa Loa (eye worm) hypothetical protein 0.0026 0.0066 0.0585
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0081 0.0259 0.6943
Echinococcus multilocularis patatin phospholipase domain containing protein 0.001 0.0012 0.0063
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Schistosoma mansoni hypothetical protein 0.0016 0.0033 0.0174
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0007 0.0001 0.0036
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0014 0.0076
Plasmodium vivax multidrug resistance protein 1, putative 0.0011 0.0017 0.0456
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0029 0.0154
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0084 0.0268 0.2969
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0007 0.0001 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0373 1
Echinococcus granulosus cGMP dependent protein kinase 0.001 0.0014 0.0072
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0017 0.0456
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0059 0.031
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0001 0.0036
Echinococcus multilocularis mitogen activated protein kinase 0.0055 0.0169 0.0894
Mycobacterium leprae Probable lipase LipE 0.0078 0.0249 0.0248
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0066 0.0205 0.18
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0055 0.0043
Schistosoma mansoni organic anion transporter 0.0123 0.0403 0.2129
Echinococcus granulosus alpha 1A adrenergic receptor 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0078 0.0249 0.0237
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0017 0.009
Schistosoma mansoni neuropeptide receptor 0.0024 0.0059 0.031
Brugia malayi SPARC precursor 0.0084 0.0268 0.2969
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0017 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0036
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0076 0.0239 0.1264
Schistosoma mansoni hypothetical protein 0.0024 0.0059 0.031
Mycobacterium tuberculosis Probable lipase LipD 0.0078 0.0249 0.0237
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0011 0.0017 0.0005
Onchocerca volvulus 0.0024 0.0059 0.1457
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0029 0.0154
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0017 0.0456
Echinococcus granulosus tachykinin peptides receptor 99D 0.0024 0.0059 0.031
Leishmania major hypothetical protein, conserved 0.0078 0.0249 0.6675
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.001 0.0012 0.0294
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0011 0.0017 0.0422
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0059 0.031
Trypanosoma cruzi cAMP response protein 1 0.001 0.0012 0.0294
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0086 0.0454
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0175 0.0584 0.3081
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0059 0.031
Onchocerca volvulus 0.0024 0.0059 0.1457
Echinococcus multilocularis agrin 0.0084 0.0268 0.1416
Plasmodium vivax hypothetical protein, conserved 0.0078 0.0249 0.6675
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0051 0.0156 0.4173
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0057 0.1425
Echinococcus multilocularis G protein coupled receptor 139 0.0024 0.0059 0.031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0014 0.0126
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0055 0.0043
Echinococcus granulosus g protein coupled receptor 0.0024 0.0059 0.031
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.001 0.0012 0.0063
Onchocerca volvulus 0.0078 0.0249 0.617
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0259 0.6943
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0081 0.0259 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0078 0.0249 0.0237
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0011 0.0017 0.0149
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0055 0.0043
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0057 0.0302
Echinococcus multilocularis multidrug resistance protein 1 0.0011 0.0017 0.009
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Trypanosoma cruzi trypanothione reductase, putative 0.0067 0.0209 0.5176
Leishmania major hypothetical protein, conserved 0.001 0.0012 0.0319
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0055 0.1465
Schistosoma mansoni lamin 0.0055 0.0169 0.0895
Trypanosoma cruzi MFS transporter, putative 0.0123 0.0403 1
Trypanosoma cruzi protein kinase A regulatory subunit 0.001 0.0012 0.0294
Echinococcus granulosus neuropeptide s receptor 0.0024 0.0059 0.031
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0014 0.0076
Leishmania major cytochrome p450-like protein 0.0022 0.0055 0.1465
Schistosoma mansoni neuropeptide receptor 0.0024 0.0059 0.031
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0319
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Brugia malayi hypothetical protein 0.0024 0.0059 0.0651
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.001 0.0012 0.0063
Entamoeba histolytica P-glyco protein 6, putative 0.0011 0.0017 0.0456
Echinococcus granulosus serotonin receptor 0.0024 0.0059 0.031
Echinococcus multilocularis multidrug resistance protein 1 0.0008 0.0005 0.0026
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0014 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0014 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0014 0.0126
Schistosoma mansoni hypothetical protein 0.0022 0.0055 0.0288
Loa Loa (eye worm) hypothetical protein 0.0022 0.0053 0.0468
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0081 0.0259 0.1366
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0084 0.0268 0.2969
Onchocerca volvulus 0.0024 0.0059 0.1457
Echinococcus granulosus hypothetical protein 0.0024 0.0059 0.031
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0055 0.0043
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0059 0.031
Trichomonas vaginalis taga, putative 0.0011 0.0017 0.0456
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0024 0.0059 0.031
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0059 0.031
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0029 0.0256
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0123 0.0403 0.3546
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0014 0.0159
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0065 0.1621
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0017 0.009
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0024 0.0059 0.0517
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0014 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0014 0.0072
Onchocerca volvulus Neuropeptide F receptor homolog 0.0024 0.0059 0.1457
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0001 0.0036
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0055 0.0043
Leishmania major p-glycoprotein 0.0011 0.0017 0.0456
Schistosoma mansoni biogenic amine receptor 0.0024 0.0059 0.031
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0029 0.0154
Echinococcus multilocularis ubiquitin specific protease 41 0.0081 0.0259 0.1366
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0057 0.1536
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0036
Brugia malayi sulfakinin receptor protein 0.0024 0.0059 0.0651
Echinococcus multilocularis G-protein coupled receptor, putative 0.0024 0.0059 0.031
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0055 0.1465
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0017 0.0456
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0017 0.0456
Trypanosoma brucei cysteinyl-tRNA synthetase, putative 0.0042 0.0123 0.3311
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0007 0.0001 0.0036
Schistosoma mansoni ran 0.0023 0.0057 0.0302
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0126
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0029 0.0154
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.001 0.0012 0.0063
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0057 0.0302
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0086 0.2306
Echinococcus granulosus neuropeptide receptor 0.0024 0.0059 0.031
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0014 0.0076
Echinococcus granulosus G protein coupled receptor 139 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.007 0.037
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0023 0.0057 0.1542
Loa Loa (eye worm) cytochrome P450 family protein 0.0078 0.0246 0.2164
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0059 0.031
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0059 0.031
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.001 0.0012 0.0294
Loa Loa (eye worm) hypothetical protein 0.0042 0.0123 0.1085
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0017 0.0456
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.0029 0.0154
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0023 0.0057 0.1542
Schistosoma mansoni opsin-like receptor 0.0024 0.0059 0.031
Schistosoma mansoni transcription factor btf3 0.0114 0.0373 0.1968
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0053 0.0281
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0014 0.0076
Leishmania major importin beta-1 subunit, putative 0.0025 0.0065 0.1754
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0014 0.0076
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0023 0.0057 0.0303
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0014 0.0126
Brugia malayi beta-lactamase 0.0078 0.0249 0.2755
Brugia malayi hypothetical protein 0.0024 0.0059 0.0651
Mycobacterium ulcerans esterase/lipase LipP 0.0078 0.0249 0.0237
Entamoeba histolytica P-glycoprotein-2 0.0011 0.0017 0.0456
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0033 0.0815
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0076 0.0239 0.265
Schistosoma mansoni amine GPCR 0.0024 0.0059 0.031
Schistosoma mansoni hypothetical protein 0.0055 0.0167 0.0882
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0055 0.0043
Echinococcus granulosus histone acetyltransferase KAT2B 0.0051 0.0156 0.0821
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0126
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0023 0.0057 0.1425
Plasmodium vivax glutathione reductase, putative 0.0067 0.0209 0.56
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0076 0.0239 0.2104
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.001 0.0012 0.0063
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0033 0.0174
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0249 0.6675
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0017 0.009
Schistosoma mansoni histamine h1 receptor 0.0024 0.0059 0.031
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0023 0.0057 0.0046
Leishmania major trypanothione reductase 0.0067 0.0209 0.56
Echinococcus granulosus lamin dm0 0.0055 0.0169 0.0895
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0023 0.0057 0.0056
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0055 0.0043
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0001 0.0036
Leishmania major hypothetical protein, conserved 0.001 0.0012 0.0319
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0055 0.0169 0.4542
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Plasmodium vivax thioredoxin reductase, putative 0.0067 0.0209 0.56
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.0029 0.0154
Trypanosoma brucei transcription factor BTF3, putative 0.0114 0.0373 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0249 0.2188
Loa Loa (eye worm) hypothetical protein 0.0084 0.0268 0.2357
Onchocerca volvulus 0.0055 0.0169 0.4202
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0024 0.0059 0.031
Echinococcus multilocularis g-protein coupled receptor 0.0024 0.0059 0.031
Brugia malayi steroid hormone receptor 0.0011 0.0014 0.0159
Brugia malayi beta-NAC-like protein 0.0114 0.0373 0.4127
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0059 0.031
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0084 0.0268 0.6649
Onchocerca volvulus Putative organic anion transporter 0.0123 0.0403 1
Brugia malayi Dopamine receptor protein 2 0.0024 0.0059 0.0651
Loa Loa (eye worm) hypothetical protein 0.0016 0.0033 0.0293
Wolbachia endosymbiont of Brugia malayi cysteinyl-tRNA synthetase 0.0042 0.0123 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0014 0.0126
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0014 0.0076
Trichomonas vaginalis adenylate cyclase type, putative 0.0007 0.0001 0.0036
Schistosoma mansoni cytochrome P450 0.0022 0.0055 0.0288
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0059 0.031
Toxoplasma gondii NADPH-glutathione reductase 0.0023 0.0057 0.1425
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0084 0.0268 0.6649
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0059 0.031
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0057 0.1419
Brugia malayi Death domain containing protein 0.0016 0.0033 0.0364
Brugia malayi larval opioid receptor 0.0024 0.0059 0.0651
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0014 0.0159
Brugia malayi acetyltransferase, GNAT family protein 0.0175 0.0584 0.646
Echinococcus granulosus dro:myosuppressin receptor 0.0024 0.0059 0.031
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0023 0.0057 0.0303
Trypanosoma cruzi cytochrome P450, putative 0.0078 0.0246 0.6102
Schistosoma mansoni cysteinyl-tRNA synthetase 0.0042 0.0123 0.0652
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0011 0.0017 0.0456
Schistosoma mansoni hypothetical protein 0.0335 0.1138 0.6005
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0033 0.0174
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.001 0.0012 0.0319
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0059 0.031
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0029 0.0781
Leishmania major regulatory subunit of protein kinase a-like protein 0.001 0.0012 0.0319
Brugia malayi Tachykinin-like peptides receptor 99D 0.0024 0.0059 0.0651
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0017 0.009
Brugia malayi Egg laying defective protein 4 0.001 0.0014 0.0151
Brugia malayi Melatonin receptor type 1A 0.0024 0.0059 0.0651
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0029 0.0154
Echinococcus multilocularis neuropeptide s receptor 0.0024 0.0059 0.031
Leishmania major protein kinase, putative 0.001 0.0014 0.0365
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0059 0.031
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0123 0.0403 0.2129
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0014 0.0159
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.008 0.0705
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Echinococcus granulosus geminin 0.0553 0.1894 1
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.001 0.0014 0.0337
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0024 0.0059 0.031
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0017 0.0456
Loa Loa (eye worm) hypothetical protein 0.0084 0.0268 0.2357
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0023 0.0057 0.1542
Entamoeba histolytica hypothetical protein 0.0114 0.0373 1
Trypanosoma cruzi transcription factor btf3, putative 0.0114 0.0373 0.9242
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0055 0.1354
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0014 0.0076
Schistosoma mansoni alpha-1 adrenergic receptor 0.0024 0.0059 0.031
Echinococcus granulosus follistatin 0.0084 0.0268 0.1416
Brugia malayi prostaglandin transporter 0.0123 0.0403 0.4465
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0029 0.0154
Loa Loa (eye worm) hypothetical protein 0.0015 0.0029 0.0256
Brugia malayi Importin beta-1 subunit 0.0031 0.0086 0.0951
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0059 0.031
Echinococcus granulosus snurportin 1 0.0335 0.1138 0.6005
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.001 0.0012 0.0063
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0017 0.0456
Trypanosoma cruzi trypanothione reductase, putative 0.0023 0.0057 0.1425
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0059 0.031
Schistosoma mansoni ran 0.0023 0.0057 0.0302
Brugia malayi sodium-independent organic anion transporter family protein 0.0123 0.0403 0.4465
Entamoeba histolytica Ran family GTPase 0.0023 0.0057 0.1536
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0007 0.0001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0081 0.0259 0.1366
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0033 0.0176
Trypanosoma brucei protein kinase, putative 0.0055 0.0169 0.4542
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.001 0.0012 0.0063
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.001 0.0012 0.0294
Brugia malayi intermediate filament protein 0.0055 0.0169 0.1876
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0023 0.0057 0.1542
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Echinococcus granulosus multidrug resistance protein 1 0.0008 0.0005 0.0026
Trichomonas vaginalis cysteinyl-tRNA synthetase, putative 0.0042 0.0123 0.3311
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0055 0.0169 0.4198
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0055 0.0169 0.4542
Onchocerca volvulus 0.0123 0.0403 1
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0084 0.0268 0.2357
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0059 0.031
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0029 0.0781
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0126
Brugia malayi Dopamine receptor 0.0024 0.0059 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0036
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0023 0.0057 0.0046
Entamoeba histolytica transcription factor BTF3, putative 0.0114 0.0373 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Brugia malayi G protein-coupled receptor 0.0024 0.0059 0.0651
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0051 0.0156 0.3857
Schistosoma mansoni hypothetical protein 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0055 0.0169 0.4198
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0055 0.0043
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Echinococcus granulosus cGMP dependent protein kinase 1 0.001 0.0014 0.0072
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0055 0.0043
Trichomonas vaginalis glutathione reductase, putative 0.0023 0.0057 0.1542
Brugia malayi RNA, U transporter 1 0.0089 0.0286 0.317
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0123 0.0403 0.2129
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0055 0.0043
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0029 0.0154
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0055 0.0043
Mycobacterium tuberculosis Probable oxidoreductase 0.0023 0.0057 0.0046
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0033 0.0364
Toxoplasma gondii NAC domain-containing protein 0.0114 0.0373 0.9242
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0335 0.1138 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0084 0.0268 0.6649
Echinococcus multilocularis 0.0022 0.0055 0.0288
Brugia malayi follicle stimulating hormone receptor 0.0267 0.0903 1
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0036
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0024 0.0059 0.031
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.001 0.0012 0.0319
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0017 0.009
Echinococcus granulosus mitogen activated protein kinase 0.0055 0.0169 0.0894
Echinococcus granulosus single minded 2 0.0007 0.0001 0.0007
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0065 0.1754
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0014 0.0159
Trichomonas vaginalis adenylate cyclase type, putative 0.0007 0.0001 0.0036
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Loa Loa (eye worm) hypothetical protein 0.0081 0.0259 0.2275
Schistosoma mansoni neuropeptide receptor 0.0024 0.0059 0.031
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0059 0.031
Plasmodium falciparum thioredoxin reductase 0.0023 0.0057 0.1542
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0057 0.1425
Brugia malayi hypothetical protein 0.0024 0.0059 0.0651
Trichomonas vaginalis bromodomain-containing protein, putative 0.0051 0.0156 0.4173
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0014 0.0076
Schistosoma mansoni peptidase 0.0007 0.0002 0.0009
Loa Loa (eye worm) cytochrome P450 0.0022 0.0055 0.048
Echinococcus granulosus leucyl tRNA synthetase 0.0042 0.0123 0.0652
Schistosoma mansoni lamin 0.0055 0.0169 0.0895
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0373 1
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0019 0.0098
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0059 0.0517
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0169 0.1876
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0126
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.0029 0.0154
Schistosoma mansoni intermediate filament proteins 0.0055 0.0169 0.0895
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0175 0.0584 0.3081
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0053 0.0281
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0017 0.0456
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0123 0.0403 0.2129
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0055 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0059 0.031
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0055 0.0043
Schistosoma mansoni coup transcription factor 0.0011 0.0014 0.0076
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0055 0.048
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0057 0.1419
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0023 0.0057 0.1542
Trichomonas vaginalis esterase, putative 0.0078 0.0249 0.6675
Schistosoma mansoni netrin receptor unc5 0.0016 0.0033 0.0174
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0169 0.149
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0059 0.0517
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0059 0.031
Schistosoma mansoni hypothetical protein 0.0553 0.1894 1
Schistosoma mansoni hypothetical protein 0.0553 0.1894 1
Mycobacterium ulcerans beta-lactamase 0.0078 0.0249 0.0237
Echinococcus multilocularis lamin dm0 0.0055 0.0169 0.0895
Trypanosoma cruzi transcription factor btf3, putative 0.0114 0.0373 0.9242
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0055 0.0043
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0014 0.0159
Brugia malayi ecdysteroid receptor 0.0011 0.0014 0.0159
Treponema pallidum cysteinyl-tRNA synthetase 0.0042 0.0123 1
Trichomonas vaginalis adenylate cyclase type III, putative 0.0007 0.0001 0.0036
Plasmodium falciparum cysteine--tRNA ligase 0.0042 0.0123 0.3311
Loa Loa (eye worm) TYRA-2 protein 0.0024 0.0059 0.0517
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.001 0.0012 0.0063
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0023 0.0057 0.1425
Echinococcus granulosus beta LACTamase domain containing family member 0.0078 0.0249 0.1314
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0011 0.0017 0.0087
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0055 0.1354
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0007 0.0001 0.0036
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0055 0.0169 0.4542
Echinococcus multilocularis sex peptide receptor 0.0024 0.0059 0.031
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0078 0.0249 0.2188
Plasmodium falciparum cGMP-dependent protein kinase 0.001 0.0014 0.0365
Leishmania major cytochrome p450-like protein 0.0078 0.0246 0.6602
Loa Loa (eye worm) hypothetical protein 0.0078 0.0249 0.2188
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0017 0.009
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0078 0.0246 0.0235
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0014 0.0076
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0017 0.0456
Brugia malayi G protein-coupled receptor F59B2.13 0.0024 0.0059 0.0651
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0051 0.0156 0.4173
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.001 0.0012 0.0063
Echinococcus granulosus fmrfamide receptor 0.0024 0.0059 0.031
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0007 0.0001 0.0036
Echinococcus granulosus agrin 0.0084 0.0268 0.1416
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0024 0.0059 0.0651
Schistosoma mansoni multidrug resistance protein 0.0011 0.0017 0.009
Mycobacterium leprae Conserved hypothetical protein 0.001 0.0012 0.0011
Toxoplasma gondii cysteine-tRNA synthetase (CysRS) 0.0042 0.0123 0.306
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.001 0.0012 0.0063
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0259 0.6417
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Echinococcus granulosus sex peptide receptor 0.0024 0.0059 0.031
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.001 0.0012 0.0063
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0059 0.031
Trichomonas vaginalis abcb9, putative 0.0011 0.0017 0.0456
Brugia malayi Protein kinase domain containing protein 0.0017 0.0035 0.0383
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0059 0.031
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0055 0.0043
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0014 0.0356
Echinococcus multilocularis thioredoxin glutathione reductase 0.0067 0.0209 0.1102
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0059 0.031
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.0567 0.2991
Loa Loa (eye worm) ICD-1 protein 0.0114 0.0373 0.3277
Onchocerca volvulus Putative organic anion transporter 0.0123 0.0403 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0024 0.0059 0.031
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0065 0.1754
Leishmania major protein kinase A regulatory subunit, putative 0.001 0.0012 0.0319
Brugia malayi Cytochrome P450 family protein 0.0078 0.0246 0.2724
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0023 0.0057 0.1542
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0059 0.031
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0059 0.031
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0023 0.0057 0.1542
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.001 0.0012 0.0104
Onchocerca volvulus 0.0123 0.0403 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0011 0.0017 0.046
Onchocerca volvulus 0.0024 0.0059 0.1457
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0055 0.0043
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.001 0.0012 0.0131
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0055 0.0043
Echinococcus granulosus ubiquitin specific protease 41 0.0081 0.0259 0.1366
Schistosoma mansoni multidrug resistance protein 0.0011 0.0017 0.009
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0141 0.3774
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0259 0.6943
Mycobacterium leprae putative cytochrome p450 0.0022 0.0055 0.0053
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0126
Toxoplasma gondii ABC1 family protein 0.0078 0.0249 0.617
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0059 0.031
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0249 0.6675
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Brugia malayi multidrug resistance protein 3 0.0011 0.0017 0.0188
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0086 0.2131
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0055 0.0043
Trypanosoma brucei cytochrome P450, putative 0.0078 0.0246 0.6602
Echinococcus granulosus somatostatin receptor 0.0024 0.0059 0.031
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0024 0.0059 0.0651
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0059 0.031
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0059 0.031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0014 0.0159
Trichomonas vaginalis abcb9, putative 0.0011 0.0017 0.0456
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0059 0.031
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0024 0.0059 0.031
Echinococcus granulosus death domain containing protein 0.0016 0.0033 0.0174
Chlamydia trachomatis cysteine--tRNA ligase 0.0042 0.0123 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0057 0.1425
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Echinococcus multilocularis Ankyrin 0.0016 0.0033 0.0176
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0169 0.4198
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0081 0.0259 0.6417
Echinococcus multilocularis expressed protein 0.0084 0.0268 0.1416
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0059 0.031
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0017 0.009
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0001 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0083 0.0263 0.1391
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0014 0.0356
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0001 0.0036
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.001 0.0012 0.0063
Loa Loa (eye worm) hypothetical protein 0.0084 0.0268 0.2357
Onchocerca volvulus 0.0084 0.0268 0.6649
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.001 0.0012 0.0319
Toxoplasma gondii protease inhibitor PI2 0.0084 0.0268 0.6649
Schistosoma mansoni amine GPCR 0.0024 0.0059 0.031
Echinococcus multilocularis cysteinyl tRNA synthetase 0.0042 0.0123 0.0652
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0029 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0259 0.6943
Loa Loa (eye worm) beta-lactamase 0.0078 0.0249 0.2188
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0014 0.0356
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0081 0.0259 0.1366
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0029 0.0154
Plasmodium vivax cysteine--tRNA ligase, putative 0.0042 0.0123 0.3311
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0017 0.0456
Echinococcus granulosus g protein coupled receptor 0.0024 0.0059 0.031
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0055 0.0043
Onchocerca volvulus 0.0024 0.0059 0.1457
Brugia malayi RE15519p 0.0024 0.0059 0.0651
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0059 0.031
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0059 0.0517
Brugia malayi cytochrome P450 0.0022 0.0055 0.0605
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0057 0.1425
Schistosoma mansoni growth hormone secretagogue receptor 0.0024 0.0059 0.031
Brugia malayi ORL1-like opioid receptor 0.0024 0.0059 0.0651
Schistosoma mansoni opsin-like receptor 0.0024 0.0059 0.031
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.001 0.0012 0.0063
Onchocerca volvulus 0.0024 0.0059 0.1457
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0078 0.0249 0.0237
Schistosoma mansoni agrin 0.0084 0.0268 0.1416
Brugia malayi hypothetical protein 0.0024 0.0059 0.0651
Schistosoma mansoni similar to Protein C20orf152 homolog 0.001 0.0012 0.0063
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0023 0.0057 0.1542
Onchocerca volvulus 0.0024 0.0059 0.1457
Echinococcus multilocularis serotonin receptor 0.0024 0.0059 0.031
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0012 0.0294
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0104
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0055 0.0043
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0033 0.0174
Onchocerca volvulus 0.0024 0.0059 0.1457
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0014 0.0126
Onchocerca volvulus 0.0055 0.0169 0.4202
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0024 0.0059 0.0651
Schistosoma mansoni organic anion transporter 0.0123 0.0403 0.2129
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0017 0.0456
Leishmania major cyclic nucleotide-binding protein-like protein 0.001 0.0012 0.0319
Leishmania major hypothetical protein, unknown function 0.001 0.0012 0.0319
Brugia malayi MAP kinase sur-1 0.0055 0.0169 0.1874
Leishmania major basic transcription factor 3a, putative 0.0114 0.0373 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0059 0.031
Trichomonas vaginalis hypothetical protein 0.0007 0.0001 0.0036
Onchocerca volvulus 0.0123 0.0403 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0014 0.0076
Echinococcus multilocularis dro:myosuppressin receptor 0.0024 0.0059 0.031
Entamoeba histolytica hypothetical protein 0.0025 0.0065 0.1754
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0024 0.0059 0.0517
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0053 0.0281
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0059 0.031
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0055 0.0043
Echinococcus granulosus cysteinyl tRNA synthetase 0.0042 0.0123 0.0652
Onchocerca volvulus 0.0042 0.0123 0.306
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Echinococcus multilocularis multidrug resistance protein 1 0.0011 0.0017 0.009
Echinococcus multilocularis mitogen activated protein kinase 3 0.0055 0.0169 0.0894
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0169 0.149
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0033 0.0289
Mycobacterium ulcerans lipase LipD 0.0078 0.0249 0.0237
Giardia lamblia NADH oxidase lateral transfer candidate 0.0023 0.0057 0.2221
Loa Loa (eye worm) glutathione reductase 0.0067 0.0209 0.1835
Loa Loa (eye worm) hypothetical protein 0.0123 0.0403 0.3546
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0023 0.0057 0.0303
Schistosoma mansoni biogenic amine receptor 0.0024 0.0059 0.031
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0007 0.0001 0.0036
Echinococcus multilocularis musashi 0.0055 0.0169 0.0895
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Echinococcus granulosus allatostatin A receptor 0.0024 0.0059 0.031
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.001 0.0012 0.0063
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0024 0.0059 0.031
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0055 0.0043
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Brugia malayi hypothetical protein 0.0123 0.0403 0.4465
Trypanosoma brucei protein kinase A regulatory subunit 0.001 0.0012 0.0319
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0249 0.617
Giardia lamblia Kinase, CMGC MAPK 0.0055 0.0169 0.6542
Echinococcus multilocularis geminin 0.0553 0.1894 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0149
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0059 0.031
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0024 0.0059 0.031
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0017 0.0456
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0053 0.0281
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.007 0.037
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0081 0.0259 0.1366
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0014 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0055 0.0043
Toxoplasma gondii thioredoxin reductase 0.0067 0.0209 0.5176
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0249 0.6675
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0059 0.031
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0011 0.0017 0.009
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0169 0.4542
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0014 0.0159
Schistosoma mansoni hypothetical protein 0.0007 0.0001 0.0007
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0033 0.0174
Echinococcus granulosus 7TM GPCR rhodopsin 0.0024 0.0059 0.031
Schistosoma mansoni serine/threonine protein kinase 0.0055 0.0169 0.0894
Leishmania major hypothetical protein, conserved 0.001 0.0012 0.0319
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0065 0.1754
Echinococcus granulosus patatin phospholipase domain containing protein 0.001 0.0012 0.0063
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0017 0.0456
Schistosoma mansoni smdr2 0.0011 0.0017 0.009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0059 0.031
Echinococcus multilocularis ATP binding cassette sub family B 0.0011 0.0017 0.0087
Brugia malayi neuropeptide F receptor 0.0024 0.0059 0.0651
Brugia malayi beta-lactamase family protein 0.0078 0.0249 0.2755
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0023 0.0057 0.1542
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0259 0.6943
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0014 0.0076
Brugia malayi hypothetical protein 0.0024 0.0059 0.0651
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0053 0.0281
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.001 0.0012 0.0063
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0082 0.0262 0.1384
Echinococcus granulosus orexin receptor type 2 0.0024 0.0059 0.031
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0055 0.0169 0.1489
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.001 0.0012 0.0319
Plasmodium falciparum thioredoxin reductase 0.0067 0.0209 0.56
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Loa Loa (eye worm) hypothetical protein 0.0123 0.0403 0.3546
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0014 0.0076
Brugia malayi neuropeptide F receptor 0.0024 0.0059 0.0651
Mycobacterium tuberculosis Probable hydrolase 0.0078 0.0249 0.0237
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0007 0.0001 0.0036
Loa Loa (eye worm) thioredoxin reductase 0.0067 0.0209 0.1835
Echinococcus multilocularis allatostatin A receptor 0.0024 0.0059 0.031
Plasmodium falciparum glutathione reductase 0.0067 0.0209 0.56
Entamoeba histolytica P-glycoprotein-1 0.0011 0.0017 0.0456
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0007 0.0001 0.0036
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0057 0.0634
Schistosoma mansoni neuropeptide f receptor 76f 0.0024 0.0059 0.031
Entamoeba histolytica cysteinyl-tRNA synthetase, putative 0.0042 0.0123 0.3311
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0036
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.001 0.0012 0.0294
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0059 0.031
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0055 0.0043
Echinococcus multilocularis orexin receptor type 2 0.0024 0.0059 0.031
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0014 0.0076
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0055 0.0043
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.001 0.0012 0.0294
Entamoeba histolytica P-glycoprotein 5, putative 0.0011 0.0017 0.0456
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.001 0.0012 0.0063
Trichomonas vaginalis adenylate cyclase type III, putative 0.0007 0.0001 0.0036
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0014 0.0076
Trichomonas vaginalis abcb9, putative 0.0011 0.0017 0.0456
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0014 0.0126
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.001 0.0012 0.0294
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0076 0.0239 0.1264
Echinococcus granulosus mitogen activated protein kinase 3 0.0055 0.0169 0.0894
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0011 0.0017 0.0456
Onchocerca volvulus 0.0024 0.0059 0.1457
Loa Loa (eye worm) hypothetical protein 0.0031 0.0086 0.0756
Echinococcus granulosus cyclic nucleotide gated cation channel 0.001 0.0012 0.0063
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Schistosoma mansoni myosin xvIII 0.0024 0.0059 0.031
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0055 0.0043
Brugia malayi Cytochrome P450 family protein 0.0078 0.0246 0.2724
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0014 0.0076
Trichomonas vaginalis CMGC family protein kinase 0.0055 0.0169 0.4542
Brugia malayi G-protein coupled receptor 0.0024 0.0059 0.0651
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0059 0.031
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.001 0.0012 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0055 0.0043
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0059 0.0517
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0023 0.0057 0.1425
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.2894 1 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0067 0.0209 0.0197
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0059 0.031
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0014 0.0076
Onchocerca volvulus 0.0123 0.0403 1
Echinococcus granulosus lamin 0.0055 0.0169 0.0895
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0023 0.0057 0.0046
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0141 0.5436
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0017 0.0456
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0008 0.0005 0.0134
Mycobacterium tuberculosis Probable lipase LipE 0.0078 0.0249 0.0237
Schistosoma mansoni adenoreceptor 0.0024 0.0059 0.031
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0042 0.0123 0.306
Loa Loa (eye worm) cytochrome P450 family protein 0.0078 0.0246 0.2164
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0059 0.031
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0023 0.0057 0.0636
Toxoplasma gondii transporter, major facilitator family protein 0.0123 0.0403 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0017 0.0456
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0024 0.0059 0.031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0059 0.031
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.0249 0.6675
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Trypanosoma cruzi cytochrome P450, putative 0.0078 0.0246 0.6102
Trichomonas vaginalis mercuric reductase, putative 0.0023 0.0057 0.1542
Trypanosoma cruzi Flagellar Member 6 0.001 0.0012 0.0294
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0059 0.031
Echinococcus granulosus neuropeptide receptor 0.0024 0.0059 0.031
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0007 0.0001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0016 0.0033 0.0289
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0059 0.031
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0023 0.0057 0.0046
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0055 0.0043
Leishmania major protein kinase, putative 0.001 0.0014 0.0365
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0029 0.0154
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0007 0.0001 0.0036
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0084 0.0268 0.6649
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0126
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0059 0.031
Onchocerca volvulus 0.001 0.0012 0.0294
Brugia malayi GnHR receptor homolog 0.0024 0.0059 0.0651
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0059 0.031
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0011 0.0017 0.0456
Trypanosoma brucei cAMP response protein 1, putative 0.001 0.0012 0.0319
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0059 0.031
Brugia malayi glutathione reductase 0.0067 0.0209 0.2311
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0007 0.0001 0.0036
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.001 0.0012 0.0131
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.001 0.0012 0.0063
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Onchocerca volvulus 0.0024 0.0059 0.1457
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0014 0.0076
Trypanosoma cruzi cysteinyl-tRNA synthetase, putative 0.0042 0.0123 0.306
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0024 0.0059 0.031
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0014 0.0159
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0081 0.0259 0.2865
Onchocerca volvulus 0.0024 0.0059 0.1457
Plasmodium falciparum multidrug resistance protein 1 0.0011 0.0017 0.0456
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0123 0.0403 0.3546
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0024 0.0059 0.031
Echinococcus granulosus transcription factor btf3 0.0114 0.0373 0.1968
Brugia malayi beta-lactamase family protein 0.0078 0.0249 0.2755
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0011 0.0017 0.0456
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.0042 0.0123 0.0112
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.001 0.0012 0.0319
Schistosoma mansoni biogenic amine receptor 0.0024 0.0059 0.031
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0024 0.0059 0.0651
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0007 0.0001 0.0036
Plasmodium falciparum basic transcription factor 3b, putative 0.0114 0.0373 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0051 0.0156 0.3857
Loa Loa (eye worm) acetyltransferase 0.0175 0.0584 0.513
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0014 0.0076
Loa Loa (eye worm) hypothetical protein 0.0123 0.0403 0.3546
Brugia malayi hypothetical protein 0.0024 0.0059 0.0651
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0055 0.0043
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0024 0.0059 0.0651
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0055 0.1354
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0249 0.6675
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0029 0.0154
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0014 0.0076
Brugia malayi AKH receptor 0.0024 0.0059 0.0651
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0055 0.0043
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0059 0.031
Schistosoma mansoni hypothetical protein 0.0024 0.0059 0.031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0059 0.031
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0057 0.1419
Loa Loa (eye worm) hypothetical protein 0.0026 0.0066 0.0585
Onchocerca volvulus 0.0024 0.0059 0.1457
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0023 0.0057 0.0046
Mycobacterium tuberculosis Conserved protein 0.0078 0.0249 0.0237
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Echinococcus granulosus thioredoxin glutathione reductase 0.0067 0.0209 0.1102
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0081 0.0259 0.1366
Mycobacterium ulcerans hypothetical protein 0.0078 0.0249 0.0237
Trichomonas vaginalis adenylate cyclase, putative 0.0007 0.0001 0.0036
Leishmania major cytochrome p450-like protein 0.0022 0.0055 0.1465
Loa Loa (eye worm) melatonin receptor type 1A 0.0024 0.0059 0.0517
Onchocerca volvulus 0.0024 0.0059 0.1457
Schistosoma mansoni hypothetical protein 0.0024 0.0059 0.031
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0249 0.6675
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0024 0.0059 0.0517
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0059 0.031
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0055 0.0043
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0024 0.0059 0.031
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.001 0.0012 0.0131
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0057 0.1536
Echinococcus granulosus Ankyrin 0.0016 0.0033 0.0176
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0055 0.0043
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0011 0.0017 0.0456
Schistosoma mansoni hypothetical protein 0.001 0.0012 0.0063
Loa Loa (eye worm) hypothetical protein 0.0123 0.0403 0.3546
Loa Loa (eye worm) hypothetical protein 0.0078 0.0249 0.2188
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.001 0.0012 0.0459
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0267 0.0903 0.7942
Brugia malayi hypothetical protein 0.0123 0.0403 0.4465
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0059 0.031
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0059 0.031
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0001 0.0036
Brugia malayi Uncoordinated protein 44 0.0016 0.0033 0.0364
Schistosoma mansoni serine/threonine protein kinase 0.001 0.0014 0.0072
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0104
Schistosoma mansoni amine GPCR 0.0024 0.0059 0.031
Loa Loa (eye worm) CYP4Cod1 0.0078 0.0246 0.2164
Brugia malayi Cytochrome P450 family protein 0.0022 0.0055 0.0605
Brugia malayi nuclear receptor NHR-88 0.0011 0.0014 0.0159
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0011 0.0017 0.0456
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0014 0.0159
Echinococcus granulosus g protein coupled receptor 0.0024 0.0059 0.031
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0055 0.0043
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.001 0.0012 0.0294
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0007 0.0001 0.0036
Echinococcus granulosus multidrug resistance protein 1 0.0011 0.0017 0.009
Onchocerca volvulus 0.0078 0.0249 0.617
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0078 0.0249 0.0237
Onchocerca volvulus 0.0024 0.0059 0.1457
Brugia malayi nuclear hormone receptor 0.0011 0.0014 0.0159
Echinococcus multilocularis expressed conserved protein 0.001 0.0014 0.0072
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0017 0.0456
Trypanosoma brucei Flagellar Member 6 0.001 0.0012 0.0319
Loa Loa (eye worm) hypothetical protein 0.0078 0.0249 0.2188
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0057 0.0503
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0053 0.0589
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0501 0.1712 0.1703
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0014 0.0159
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0023 0.0057 0.4088
Echinococcus granulosus Solute carrier organic anion transporter family 0.0123 0.0403 0.2129
Schistosoma mansoni amine GPCR 0.0024 0.0059 0.031
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0001 0.0036
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0059 0.031
Leishmania major cysteinyl-tRNA synthetase, putative 0.0042 0.0123 0.3311
Brugia malayi Cytochrome P450 family protein 0.0022 0.0055 0.0605
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0024 0.0059 0.031
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0029 0.0154
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0014 0.0076
Trypanosoma cruzi cAMP response protein 1, putative 0.001 0.0012 0.0294
Trichomonas vaginalis ABC transporter, putative 0.0011 0.0017 0.0456
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0059 0.031
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0222 0.5959
Schistosoma mansoni opsin-like receptor 0.0024 0.0059 0.031
Echinococcus multilocularis lamin 0.0055 0.0169 0.0895
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0014 0.0126
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0055 0.0043
Loa Loa (eye worm) hypothetical protein 0.0055 0.0169 0.1484
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0059 0.031
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0014 0.0076
Echinococcus multilocularis cGMP dependent protein kinase 1 0.001 0.0014 0.0072
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0055 0.0043
Loa Loa (eye worm) hypothetical protein 0.0084 0.0268 0.2357
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.0029 0.0154
Loa Loa (eye worm) hypothetical protein 0.0027 0.007 0.0616
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0071 0.0222 0.5959
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0053 0.0281
Echinococcus granulosus importin subunit beta 1 0.0031 0.0086 0.0454
Brugia malayi sodium-independent organic anion transporter family protein 0.0123 0.0403 0.4465
Echinococcus granulosus 7tm_1 domain containing protein 0.0024 0.0059 0.031
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0014 0.0076
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0057 0.1425
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0023 0.0057 0.1425
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0014 0.0076
Mycobacterium tuberculosis Conserved protein 0.0078 0.0249 0.0237
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0007 0.0001 0.0036
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0057 0.2212
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0014 0.0159
Entamoeba histolytica P-glycoprotein-5 0.0011 0.0017 0.0456
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0055 0.0169 0.4198
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0024 0.0059 0.1457
Echinococcus granulosus g-protein coupled receptor 0.0024 0.0059 0.031
Loa Loa (eye worm) multidrug resistance protein 3 0.0011 0.0017 0.0149
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0055 0.0043
Schistosoma mansoni 60S ribosomal protein L21 0.0012 0.0019 0.0098
Loa Loa (eye worm) hypothetical protein 0.0024 0.0059 0.0517
Schistosoma mansoni voltage-gated potassium channel 0.0083 0.0263 0.1391
Plasmodium falciparum glutathione reductase 0.0023 0.0057 0.1542
Onchocerca volvulus 0.0024 0.0059 0.1457
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0017 0.0036 0.0401
Entamoeba histolytica P-glycoprotein-2, putative 0.0011 0.0017 0.0456
Brugia malayi putative neuropeptide receptor NPR1 0.0024 0.0059 0.0651
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0011 0.0017 0.009
Echinococcus granulosus nuclear factor of activated T cells 5 0.0082 0.0262 0.1384
Echinococcus multilocularis somatostatin receptor 0.0024 0.0059 0.031
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0249 0.1314
Schistosoma mansoni amine GPCR 0.0024 0.0059 0.031
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Trichomonas vaginalis guanylate cyclase, putative 0.0007 0.0001 0.0036
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0055 0.0043
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0059 0.031
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0149
Brugia malayi Serotonin receptor 0.0024 0.0059 0.0651
Plasmodium falciparum importin beta, putative 0.0031 0.0086 0.2306
Brugia malayi sodium-independent organic anion transporter family protein 0.0123 0.0403 0.4465
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0014 0.0076
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0084 0.0268 0.2969

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.8913 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 14.7157 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (binding) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 44.6684 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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