Detailed information for compound 1413657

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 395.435 | Formula: C19H17N5O3S
  • H donors: 1 H acceptors: 6 LogP: 2.71 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1nc2ccccc2c2n1nc(n2)c1cccc(c1)S(=O)(=O)N1CCCC1
  • InChi: 1S/C19H17N5O3S/c25-19-20-16-9-2-1-8-15(16)18-21-17(22-24(18)19)13-6-5-7-14(12-13)28(26,27)23-10-3-4-11-23/h1-2,5-9,12H,3-4,10-11H2,(H,20,25)
  • InChiKey: MLXZZQXUAVHVTH-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Photinus pyralis Luciferin 4-monooxygenase Starlite/ChEMBL No references
Homo sapiens TAR DNA binding protein Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens snurportin 1 No references
Homo sapiens RAN, member RAS oncogene family No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium falciparum acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii peroxisomal-coenzyme a synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium vivax acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Get druggable targets OG5_126609 All targets in OG5_126609
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain fatty-acid CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Plasmodium berghei acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium knowlesi acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi RNA recognition motif domain containing protein Get druggable targets OG5_132461 All targets in OG5_132461
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Entamoeba histolytica acyl-CoA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus granulosus tar DNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania infantum 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania braziliensis 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni tar DNA-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Onchocerca volvulus Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) TAR-binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania donovani 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Leishmania major 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase Get druggable targets OG5_126609 All targets in OG5_126609
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi AMP-binding enzyme family protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) Get druggable targets OG5_126609 All targets in OG5_126609
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana 4-coumarate:coa ligase-like protein Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica acyl-coA synthetase, putative Get druggable targets OG5_126609 All targets in OG5_126609
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi RNA binding protein Get druggable targets OG5_132461 All targets in OG5_132461
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Get druggable targets OG5_126609 All targets in OG5_126609
Schistosoma japonicum TAR DNA-binding protein 43, putative Get druggable targets OG5_132461 All targets in OG5_132461
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_126609 All targets in OG5_126609
Mycobacterium ulcerans acyl-CoA synthetase Get druggable targets OG5_126609 All targets in OG5_126609
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 443 aa 26.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Neospora caninum acetyl-coenzyme a synthetase, putative Luciferin 4-monooxygenase   550 aa 549 aa 20.9 %
Mycobacterium ulcerans non-ribosomal peptide synthetase Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Leishmania donovani long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 463 aa 23.5 %
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 461 aa 22.3 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 484 aa 26.0 %
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 Luciferin 4-monooxygenase   550 aa 494 aa 26.3 %
Candida albicans similar to S. cerevisiae FAA4 (YMR246W) long-chain fatty acid--CoA synthetase Luciferin 4-monooxygenase   550 aa 478 aa 23.4 %
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 535 aa 23.2 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 24.7 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 476 aa 23.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Leishmania mexicana long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 483 aa 23.8 %
Trypanosoma cruzi fatty acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 480 aa 25.2 %
Theileria parva long-chain fatty acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 507 aa 23.5 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 596 aa 21.1 %
Leishmania braziliensis long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 496 aa 22.8 %
Leishmania major long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 482 aa 23.2 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 466 aa 21.7 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 527 aa 25.0 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 577 aa 22.2 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 502 aa 24.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Cryptosporidium parvum acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 25.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 601 aa 22.5 %
Onchocerca volvulus Luciferin 4-monooxygenase   550 aa 487 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 22.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 535 aa 21.7 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 497 aa 24.7 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 475 aa 21.1 %
Cryptosporidium hominis acetyl-CoenzymeA synthetase (acetate--coa ligase) (acyl-activating enzyme) Luciferin 4-monooxygenase   550 aa 549 aa 22.6 %
Leishmania infantum long chain fatty Acyl CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 500 aa 23.4 %
Candida albicans similar to S. cerevisiae FAT1 (YBR041W) fatty acid transporter and very long-chain fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 496 aa 24.2 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 558 aa 20.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 530 aa 23.8 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE Luciferin 4-monooxygenase   550 aa 502 aa 22.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 576 aa 19.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD32 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 442 aa 23.5 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 541 aa 21.4 %
Trichomonas vaginalis AMP dependent ligase, putative Luciferin 4-monooxygenase   550 aa 445 aa 26.1 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 494 aa 23.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 499 aa 19.2 %
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein Luciferin 4-monooxygenase   550 aa 476 aa 22.5 %
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 484 aa 23.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 538 aa 21.8 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 452 aa 26.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD23 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 542 aa 23.8 %
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 565 aa 22.8 %
Schistosoma japonicum ko:K08745 solute carrier family 27 (fatty acid transporter), member 1, putative Luciferin 4-monooxygenase   550 aa 501 aa 24.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 504 aa 22.6 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 593 aa 22.1 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 582 aa 22.3 %
Cryptosporidium parvum putative long chain fatty acyl CoA synthetase having a signal peptide Luciferin 4-monooxygenase   550 aa 472 aa 24.8 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 484 aa 20.5 %
Dictyostelium discoideum acetyl-CoA ligase Luciferin 4-monooxygenase   550 aa 549 aa 22.2 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 22.9 %
Loa Loa (eye worm) AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 489 aa 23.3 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 524 aa 24.0 %
Cryptosporidium parvum acetyl-coenzyme A synthetase Luciferin 4-monooxygenase   550 aa 545 aa 22.8 %
Trichomonas vaginalis antibiotic synthetase, putative Luciferin 4-monooxygenase   550 aa 581 aa 21.2 %
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 Luciferin 4-monooxygenase   550 aa 459 aa 27.0 %
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) Luciferin 4-monooxygenase   550 aa 592 aa 20.4 %
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 Luciferin 4-monooxygenase   550 aa 493 aa 22.1 %
Onchocerca volvulus Lysine-specific histone demethylase 1A homolog Luciferin 4-monooxygenase   550 aa 550 aa 22.5 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 526 aa 22.4 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 537 aa 20.9 %
Babesia bovis fatty acyl-CoA synthetase family protein Luciferin 4-monooxygenase   550 aa 461 aa 23.4 %
Mycobacterium ulcerans acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 497 aa 19.3 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 462 aa 23.8 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 531 aa 19.0 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 493 aa 20.7 %
Toxoplasma gondii type I fatty acid synthase, putative Luciferin 4-monooxygenase   550 aa 514 aa 19.8 %
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 509 aa 21.8 %
Trichomonas vaginalis AMP dependent CoA ligase, putative Luciferin 4-monooxygenase   550 aa 492 aa 23.6 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 505 aa 28.1 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 541 aa 22.4 %
Mycobacterium ulcerans putative fatty-acid--CoA ligase Luciferin 4-monooxygenase   550 aa 576 aa 20.8 %
Dictyostelium discoideum fatty acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 501 aa 24.4 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 476 aa 20.8 %
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 Luciferin 4-monooxygenase   550 aa 458 aa 25.8 %
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 495 aa 22.6 %
Neospora caninum Short-chain dehydrogenase/reductase SDR, related Luciferin 4-monooxygenase   550 aa 518 aa 19.1 %
Trypanosoma congolense fatty acyl CoA synthetase 2, putative Luciferin 4-monooxygenase   550 aa 500 aa 22.4 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 545 aa 24.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 586 aa 24.4 %
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 529 aa 22.3 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 494 aa 24.3 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. Luciferin 4-monooxygenase   550 aa 487 aa 22.4 %
Trypanosoma brucei fatty acyl CoA synthetase 3 Luciferin 4-monooxygenase   550 aa 491 aa 23.6 %
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF Luciferin 4-monooxygenase   550 aa 558 aa 20.1 %
Toxoplasma gondii propionate-CoA ligase Luciferin 4-monooxygenase   550 aa 550 aa 21.1 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 517 aa 24.8 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative Luciferin 4-monooxygenase   550 aa 480 aa 21.5 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Babesia bovis long-chain acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 445 aa 21.8 %
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Luciferin 4-monooxygenase   550 aa 533 aa 22.7 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase Luciferin 4-monooxygenase   550 aa 536 aa 24.4 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 Luciferin 4-monooxygenase   550 aa 482 aa 24.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 539 aa 19.1 %
Leishmania mexicana acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 559 aa 20.6 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Trypanosoma brucei gambiense fatty acyl CoA synthetase 4, putative Luciferin 4-monooxygenase   550 aa 497 aa 23.7 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 522 aa 19.9 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 18.3 %
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD24 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 526 aa 21.9 %
Trichomonas vaginalis AMP dependent ligase/synthetase, putative Luciferin 4-monooxygenase   550 aa 554 aa 24.4 %
Echinococcus multilocularis long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) Luciferin 4-monooxygenase   550 aa 480 aa 22.5 %
Entamoeba histolytica acyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 446 aa 22.0 %
Schistosoma japonicum ko:K01897 long-chain fatty-acid-CoA ligase [EC6.2.1.3], putative Luciferin 4-monooxygenase   550 aa 466 aa 27.3 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 478 aa 21.1 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 Luciferin 4-monooxygenase   550 aa 498 aa 23.5 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 560 aa 21.4 %
Leishmania braziliensis long-chain-fatty-acid-CoA ligase, putative Luciferin 4-monooxygenase   550 aa 504 aa 25.6 %
Echinococcus granulosus long chain fatty acid transport protein 4 Luciferin 4-monooxygenase   550 aa 476 aa 22.3 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 543 aa 24.5 %
Onchocerca volvulus Matrilysin homolog Luciferin 4-monooxygenase   550 aa 466 aa 24.2 %
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 Luciferin 4-monooxygenase   550 aa 463 aa 21.8 %
Leishmania braziliensis acetyl-CoA synthetase, putative Luciferin 4-monooxygenase   550 aa 603 aa 22.6 %
Brugia malayi AMP-binding enzyme family protein Luciferin 4-monooxygenase   550 aa 544 aa 21.5 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 507 aa 20.9 %
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative Luciferin 4-monooxygenase   550 aa 490 aa 23.3 %
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) Luciferin 4-monooxygenase   550 aa 509 aa 22.6 %
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) Luciferin 4-monooxygenase   550 aa 617 aa 22.2 %
Cryptosporidium hominis acyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 460 aa 26.1 %
Dictyostelium discoideum hypothetical protein Luciferin 4-monooxygenase   550 aa 542 aa 22.1 %
Candida albicans similar to S. cerevisiae ACS2 (YLR153C) acetyl-CoA synthetase Luciferin 4-monooxygenase   550 aa 539 aa 22.1 %
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 Luciferin 4-monooxygenase   550 aa 492 aa 24.6 %
Dictyostelium discoideum AMP-dependent synthetase and ligase domain-containing protein Luciferin 4-monooxygenase   550 aa 550 aa 20.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) RNA binding protein 0.0076 0.0142 0.0416
Echinococcus granulosus rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Echinococcus granulosus potassium voltage gated channel protein 0.0025 0 0.00000098352
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Schistosoma mansoni glutamate synthase 0.0266 0.0668 0.0827
Schistosoma mansoni jun-related protein 0.0302 0.0765 0.0947
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0019 0.0066
Echinococcus granulosus hypothetical protein 0.1673 0.456 0.5647
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.1004 0.2708 0.7947
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.1004 0.2708 0.7947
Onchocerca volvulus 0.0121 0.0266 0.0969
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0001 0.0001
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0025 0 0.00000098352
Schistosoma mansoni chromobox protein 0.0089 0.0176 0.0217
Onchocerca volvulus 0.0134 0.0301 0.1095
Schistosoma mansoni sodium-dependent amino acid transporter 0.0057 0.0089 0.011
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0001 0.0002
Echinococcus multilocularis conserved hypothetical protein 0.0025 0 0.00000098352
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.0128 0.0128
Trichomonas vaginalis glutathione reductase, putative 0.1004 0.2708 0.9864
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0668 0.2428
Echinococcus multilocularis potassium voltage gated channel protein 0.0025 0 0.00000098352
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0028
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0097 0.0198 0.0245
Echinococcus granulosus geminin 0.0722 0.1928 0.2387
Echinococcus multilocularis Polycystic kidney disease protein 0.013 0.029 0.0359
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0266 0.0668 0.2464
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0096 0.028
Brugia malayi Pre-SET motif family protein 0.0128 0.0285 0.0836
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus biogenic amine 5HT receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) acetylcholinesterase 1 0.037 0.0955 0.2801
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0266 0.0668 0.0827
Schistosoma mansoni ran 0.0026 0.0001 0.0001
Echinococcus multilocularis G-protein coupled receptor, putative 0.0134 0.0301 0.0372
Schistosoma mansoni nuclear hormone receptor 0.003 0.0013 0.0016
Schistosoma mansoni opsin-like receptor 0.0134 0.0301 0.0372
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.008 0.0287
Brugia malayi hypothetical protein 0.0134 0.0301 0.0882
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0067 0.0115 0.042
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Schistosoma mansoni hypothetical protein 0.0115 0.025 0.0309
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0057 0.0089 0.011
Loa Loa (eye worm) hypothetical protein 0.0337 0.0863 0.2533
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0199 0.0482 0.0482
Echinococcus multilocularis mitogen activated protein kinase 0.0112 0.0241 0.0299
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0013 0.0038
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.006 0.0096 0.0353
Brugia malayi Protein kinase domain containing protein 0.0034 0.0023 0.0068
Brugia malayi jmjC domain containing protein 0.0064 0.0109 0.0318
Schistosoma mansoni BC026374 protein (S09 family) 0.0063 0.0104 0.0128
Echinococcus multilocularis netrin receptor unc 5 0.0033 0.0021 0.0025
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Schistosoma mansoni rab6-interacting 0.013 0.029 0.0359
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0036 0.003 0.0037
Onchocerca volvulus 0.0063 0.0104 0.0376
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0266 0.0668 0.2428
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0266 0.0668 0.1958
Schistosoma mansoni importin beta-1 0.0035 0.0027 0.0033
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0013 0.0016
Schistosoma mansoni myosin xvIII 0.0134 0.0301 0.0372
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0266 0.0668 0.2188
Brugia malayi neuropeptide F receptor 0.0134 0.0301 0.0882
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0266 0.0668 0.1959
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0057 0.0089 0.011
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0266 0.0668 0.1937
Entamoeba histolytica hypothetical protein 0.0043 0.0051 0.0748
Echinococcus granulosus G protein coupled receptor 139 0.0134 0.0301 0.0372
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0821 0.2203 0.2203
Loa Loa (eye worm) phosphatidylinositol 3 0.0034 0.0024 0.0068
Onchocerca volvulus 0.0134 0.0301 0.1095
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.3059 0.8396 0.8396
Schistosoma mansoni hypothetical protein 0.0302 0.0765 0.0947
Loa Loa (eye worm) hypothetical protein 0.0057 0.0089 0.026
Echinococcus granulosus lamin dm0 0.0061 0.01 0.0123
Loa Loa (eye worm) hypothetical protein 0.009 0.018 0.0529
Trichomonas vaginalis glutamate synthase, putative 0.0266 0.0668 0.2428
Echinococcus multilocularis chromobox protein 1 0.0089 0.0176 0.0217
Toxoplasma gondii Erv1 / Alr family protein 0.0075 0.0139 0.0408
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0231 0.0285
Loa Loa (eye worm) hypothetical protein 0.0121 0.0266 0.0781
Trichomonas vaginalis adenylate cyclase, putative 0.0054 0.0081 0.0289
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0266 0.0668 0.2428
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0134 0.0301 0.0372
Brugia malayi hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus voltage dependent calcium channel 0.0025 0 0.00000098352
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0111 0.0398
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.008 0.0287
Echinococcus granulosus serotonin receptor 0.0134 0.0301 0.0372
Schistosoma mansoni neuropeptide F-like receptor 0.0134 0.0301 0.0372
Brugia malayi neuropeptide F receptor 0.0134 0.0301 0.0882
Echinococcus granulosus RUN 0.013 0.029 0.0359
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0001 0.0003
Plasmodium falciparum amino acid transporter, putative 0.0057 0.0089 0.0258
Brugia malayi hypothetical protein 0.0036 0.0031 0.009
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0067 0.0115 0.0309
Schistosoma mansoni thyroid hormone receptor 0.003 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0013 0.0038
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0019 0.0066
Loa Loa (eye worm) hypothetical protein 0.0036 0.003 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.0572 0.1514 0.5512
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0208 0.0752
Leishmania major acetoin dehydrogenase e3 component-like protein 0.2671 0.7322 0.7322
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0057 0.0089 0.011
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0134 0.0301 0.0882
Brugia malayi AMP-binding enzyme family protein 0.0029 0.001 0.0028
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0572 0.1514 0.4442
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0668 0.2428
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0033 0.0021 0.0025
Mycobacterium ulcerans aldehyde dehydrogenase 0.0191 0.0458 0.1688
Schistosoma mansoni hypothetical protein 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.006
Brugia malayi PAS domain containing protein 0.0209 0.0509 0.1492
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0047 0.0062 0.0061
Echinococcus multilocularis voltage dependent calcium channel 0.0025 0 0.00000098352
Echinococcus multilocularis thioredoxin glutathione reductase 0.1257 0.3407 0.4219
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0199 0.048 0.048
Loa Loa (eye worm) melatonin receptor type 1A 0.0134 0.0301 0.0882
Loa Loa (eye worm) hypothetical protein 0.037 0.0955 0.2801
Echinococcus granulosus lipoxygenase domain containing protein 0.013 0.029 0.0359
Loa Loa (eye worm) intermediate filament protein 0.0061 0.01 0.0291
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2671 0.7322 0.7322
Onchocerca volvulus 0.0063 0.0104 0.0376
Schistosoma mansoni microtubule-associated protein tau 0.2944 0.8076 1
Trypanosoma cruzi NADH dehydrogenase, putative 0.0266 0.0668 0.0667
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0044 0.0129
Brugia malayi AMP-binding enzyme family protein 0.0029 0.001 0.0028
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0012 0.0015
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0086 0.0086
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0025 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0067 0.0115 0.042
Mycobacterium ulcerans carboxylesterase, LipT 0.0063 0.0104 0.0379
Schistosoma mansoni thyroid hormone receptor 0.003 0.0013 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0013 0.0038
Brugia malayi cytochrome P450 0.0067 0.0115 0.0335
Trichomonas vaginalis glutamate synthase, putative 0.0266 0.0668 0.2428
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0067 0.0115 0.042
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0266 0.0668 0.0827
Schistosoma mansoni hypothetical protein 0.0372 0.0959 0.1187
Loa Loa (eye worm) hypothetical protein 0.013 0.029 0.085
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Brugia malayi Tachykinin-like peptides receptor 99D 0.0134 0.0301 0.0882
Schistosoma mansoni ap endonuclease 0.006 0.0096 0.0119
Onchocerca volvulus 0.0134 0.0301 0.1095
Brugia malayi Importin beta-1 subunit 0.0035 0.0027 0.0078
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0057 0.0089 0.011
Echinococcus granulosus FTZ F1 alpha 0.003 0.0013 0.0016
Echinococcus granulosus single minded 2 0.0162 0.0379 0.0469
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus multilocularis RUN 0.013 0.029 0.0359
Brugia malayi Serotonin receptor 0.0134 0.0301 0.0882
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0266 0.0668 0.1959
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Brugia malayi Cyclic-nucleotide gated cation channel 0.0036 0.003 0.0087
Echinococcus granulosus g protein coupled receptor 0.0134 0.0301 0.0372
Echinococcus multilocularis ATP binding cassette sub family G 0.0025 0.0001 0.0001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3059 0.8396 0.8396
Echinococcus multilocularis sodium leak channel non selective protein 0.0025 0 0.00000098352
Loa Loa (eye worm) norepinephrine transporter 0.0337 0.0863 0.2533
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0025 0 0.00000098352
Mycobacterium ulcerans dehydrogenase 0.0266 0.0668 0.2464
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0067 0.0115 0.0309
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0034 0.0024 0.0029
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0097 0.0198 0.0245
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0137 0.0493
Brugia malayi exodeoxyribonuclease III family protein 0.006 0.0096 0.0282
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0067 0.0115 0.0309
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0025 0 0.00000098352
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0241 0.0299
Mycobacterium tuberculosis Carboxylesterase LipT 0.0063 0.0104 0.0276
Echinococcus multilocularis potassium voltage gated channel protein 0.0025 0 0.00000098352
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.0024 0.0023
Echinococcus multilocularis snurportin 1 0.0372 0.0959 0.1187
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.008 0.0287
Onchocerca volvulus 0.003 0.0012 0.0044
Echinococcus granulosus netrin receptor unc 5 0.0033 0.0021 0.0025
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0134 0.0301 0.0372
Echinococcus multilocularis neuropeptide FF receptor 2 0.0134 0.0301 0.0372
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0266 0.0668 0.0827
Leishmania major trypanothione reductase 0.1257 0.3407 0.3407
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0034 0.0024 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0134 0.0301 0.0372
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0075 0.0139 0.0172
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.01 0.0208 0.0257
Loa Loa (eye worm) hypothetical protein 0.0406 0.1053 0.3089
Echinococcus granulosus short transient receptor potential channel 6 0.0025 0 0.00000098352
Schistosoma mansoni transient receptor potential channel 4 0.0025 0 0.00000098352
Echinococcus granulosus ryanodine receptor 44f 0.0025 0 0.00000098352
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0266 0.0668 0.0667
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.026 0.3883
Echinococcus multilocularis G protein coupled receptor 139 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0025 0.0001 0.0002
Plasmodium falciparum transporter, putative 0.0057 0.0089 0.0258
Schistosoma mansoni gliotactin 0.0063 0.0104 0.0128
Schistosoma mansoni survival motor neuron protein 0.0158 0.0368 0.0456
Trypanosoma cruzi target of rapamycin kinase 3 0.008 0.0151 0.0151
Brugia malayi Carboxylesterase family protein 0.0063 0.0104 0.0303
Echinococcus multilocularis hyperpolarization activated cyclic 0.0036 0.003 0.0037
Brugia malayi Heterochromatin protein 1 0.0089 0.0176 0.0514
Brugia malayi AMP-binding enzyme family protein 0.0029 0.001 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0134 0.0301 0.0372
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.008 0.0151 0.0151
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0137 0.0493
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0199 0.048 0.0594
Brugia malayi G-protein coupled receptor 0.0134 0.0301 0.0882
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0067 0.0115 0.0309
Brugia malayi 6-phosphofructokinase 0.0119 0.026 0.0762
Echinococcus granulosus chromobox protein 1 0.0089 0.0176 0.0217
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0385 0.0995 0.2919
Brugia malayi GnHR receptor homolog 0.0134 0.0301 0.0882
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0025 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0025 0 0.00000098352
Echinococcus multilocularis ATP binding cassette sub family G 0.0025 0.0001 0.0001
Onchocerca volvulus 0.0134 0.0301 0.1095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Onchocerca volvulus 0.0061 0.01 0.0361
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.001 0.0134
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.01 0.0208 0.3105
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0019 0.0056
Echinococcus multilocularis carboxylesterase 5A 0.037 0.0955 0.1182
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0128 0.0285 0.0353
Echinococcus multilocularis musashi 0.0061 0.01 0.0123
Leishmania major importin beta-1 subunit, putative 0.0028 0.0009 0.0008
Echinococcus multilocularis mitogen activated protein kinase 3 0.0112 0.0241 0.0299
Echinococcus multilocularis g-protein coupled receptor 0.0134 0.0301 0.0372
Brugia malayi hypothetical protein 0.0056 0.0086 0.0252
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0067 0.0115 0.042
Onchocerca volvulus 0.0029 0.001 0.0034
Onchocerca volvulus 0.0134 0.0301 0.1095
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0013 0.0016
Brugia malayi hypothetical protein 0.013 0.029 0.085
Treponema pallidum thioredoxin reductase (trxB) 0.0266 0.0668 0.2411
Echinococcus granulosus potassium large conductance calcium activated 0.0025 0 0.00000098352
Brugia malayi RNA binding protein 0.0076 0.0142 0.0416
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0199 0.048 0.0594
Echinococcus multilocularis sodium and chloride dependent glycine 0.0057 0.0089 0.011
Giardia lamblia Thioredoxin reductase 0.0266 0.0668 0.2466
Toxoplasma gondii exonuclease III APE 0.006 0.0096 0.0282
Echinococcus granulosus rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0027 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0096 0.0346
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0013 0.0016
Plasmodium vivax ferrodoxin reductase, putative 0.0266 0.0668 0.1958
Echinococcus multilocularis ryanodine receptor 44f 0.0025 0 0.00000098352
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0096 0.0346
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0013 0.0038
Echinococcus granulosus tm gpcr rhodopsin 0.1981 0.5412 0.6702
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Brugia malayi nuclear receptor NHR-88 0.003 0.0013 0.0038
Echinococcus granulosus nuclear factor of activated T cells 5 0.0167 0.0392 0.0485
Brugia malayi hypothetical protein 0.0476 0.1248 0.3663
Toxoplasma gondii target of rapamycin (TOR), putative 0.0075 0.0137 0.0401
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0167 0.0392 0.0485
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0097 0.0198 0.0245
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0266 0.0668 0.2466
Echinococcus multilocularis transient receptor potential gamma protein 0.0025 0 0.00000098352
Loa Loa (eye worm) hypothetical protein 0.0057 0.0089 0.026
Leishmania major hypothetical protein, conserved 0.0075 0.0139 0.0139
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0013 0.0016
Brugia malayi hypothetical protein 0.013 0.029 0.085
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0067 0.0115 0.0309
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0.0001 0.0001
Brugia malayi RE15519p 0.0134 0.0301 0.0882
Brugia malayi Carboxylesterase family protein 0.0063 0.0104 0.0303
Echinococcus granulosus g protein coupled receptor 0.0134 0.0301 0.0372
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0012 0.0015
Echinococcus granulosus transient receptor potential cation channel 0.0025 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.008 0.0287
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0067 0.0115 0.042
Leishmania major hypothetical protein, conserved 0.0266 0.0668 0.0667
Echinococcus multilocularis acetylcholinesterase 0.037 0.0955 0.1182
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0199 0.048 0.0594
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0266 0.0668 0.2428
Schistosoma mansoni transient receptor potential channel 0.0025 0 0.000001021
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0199 0.0482 0.1779
Giardia lamblia GTOR 0.01 0.0208 0.0768
Mycobacterium ulcerans glutamate synthase subunit beta 0.0266 0.0668 0.2464
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0061 0.01 0.0291
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0266 0.0668 0.0827
Brugia malayi M-phase phosphoprotein, mpp8 0.0121 0.0266 0.0781
Loa Loa (eye worm) TYRA-2 protein 0.0134 0.0301 0.0882
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0057 0.0089 0.026
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.3639 1 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0501 0.1317 0.3846
Toxoplasma gondii cytochrome p450 superfamily protein 0.0067 0.0115 0.0335
Echinococcus granulosus potassium voltage gated channel protein 0.0025 0 0.00000098352
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0142 0.0176
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0036 0.003 0.0087
Loa Loa (eye worm) neuropeptide F receptor 0.0134 0.0301 0.0882
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0025 0 0.00000098352
Brugia malayi olfactory channel protein osm-9 0.0025 0.0001 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0396 0.1025 0.3732
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0019 0.0072
Onchocerca volvulus 0.0134 0.0301 0.1095
Onchocerca volvulus 0.0063 0.0104 0.0376
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0013 0.0038
Schistosoma mansoni chromobox protein 0.0089 0.0176 0.0217
Echinococcus granulosus hypothetical protein 0.0025 0 0.00000098352
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0112 0.0241 0.0241
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0034 0.0024 0.0023
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0055 0.0084 0.0083
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0084 0.0083
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0019 0.0056
Leishmania major cytochrome p450-like protein 0.0067 0.0115 0.0114
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0086 0.0086
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0013 0.0038
Trypanosoma brucei PAB1-binding protein , putative 0.0056 0.0086 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0005 0.0013
Echinococcus granulosus importin subunit beta 1 0.0035 0.0027 0.0033
Brugia malayi Carboxylesterase family protein 0.0063 0.0104 0.0303
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0025 0 0.00000098352
Echinococcus granulosus shaker cognate 0.0025 0 0.00000098352
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0406 0.1053 0.3089
Giardia lamblia Glutamate synthase 0.0266 0.0668 0.2466
Trichomonas vaginalis glucosylceramidase, putative 0.0375 0.0969 0.3528
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0013 0.0016
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0134 0.0301 0.0372
Schistosoma mansoni hypothetical protein 0.013 0.029 0.0359
Echinococcus multilocularis fmrfamide receptor 0.0134 0.0301 0.0372
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0266 0.0668 0.1959
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Brugia malayi hypothetical protein 0.0134 0.0301 0.0882
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0013 0.0016
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0051 0.0062
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus neuropeptide Y receptor 0.0134 0.0301 0.0372
Echinococcus multilocularis transfer RNA-Lys 0.0155 0.0358 0.0443
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0025 0 0.00000098352
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0057 0.0089 0.026
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0199 0.048 0.177
Trichomonas vaginalis PIKK family atypical protein kinase 0.0086 0.0167 0.0605
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Schistosoma mansoni hypothetical protein 0.0134 0.0301 0.0372
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.001 0.0033
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0266 0.0668 0.2464
Echinococcus multilocularis serotonin transporter 0.0337 0.0863 0.1069
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0057 0.0089 0.011
Echinococcus granulosus voltage dependent calcium channel 0.0025 0 0.00000098352
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0025 0 0.00000098352
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0067 0.0115 0.0309
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0057 0.0089 0.011
Echinococcus granulosus fmrfamide receptor 0.0134 0.0301 0.0372
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0067 0.0115 0.0309
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0266 0.0668 1
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0266 0.0668 1
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0025 0 0.00000098352
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0028
Schistosoma mansoni neuropeptide F-like receptor 0.0134 0.0301 0.0372
Trichomonas vaginalis glucosylceramidase, putative 0.0572 0.1514 0.5512
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0142 0.0176
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0134 0.0301 0.0882
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0009 0.0026
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0051 0.0062
Loa Loa (eye worm) hypothetical protein 0.0337 0.0863 0.2533
Echinococcus granulosus neuropeptide receptor 0.0134 0.0301 0.0372
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3639 1 1
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0266 0.0668 0.1937
Brugia malayi hypothetical protein 0.0292 0.0737 0.2163
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0013 0.0016
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1257 0.3407 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0137 0.0493
Loa Loa (eye worm) hypothetical protein 0.0776 0.2077 0.6095
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0134 0.0301 0.0372
Brugia malayi Carboxylesterase family protein 0.0063 0.0104 0.0303
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0 0.000001021
Brugia malayi Dopamine receptor 0.0134 0.0301 0.0882
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0134 0.0301 0.0882
Brugia malayi Dopamine receptor protein 2 0.0134 0.0301 0.0882
Schistosoma mansoni jumonji domain containing protein 0.0064 0.0109 0.0134
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0081 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0134 0.0301 0.0372
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0076 0.014 0.0506
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0266 0.0668 0.2464
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.001 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0151 0.0546
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.1004 0.2708 0.7947
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0054 0.008 0.0233
Echinococcus multilocularis short transient receptor potential channel 6 0.0025 0 0.00000098352
Echinococcus granulosus rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Plasmodium vivax glutathione reductase, putative 0.1257 0.3407 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0067 0.0115 0.0114
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0134 0.0301 0.0372
Leishmania major NADH dehydrogenase, putative 0.0266 0.0668 0.0667
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0057 0.0089 0.011
Echinococcus granulosus short transient receptor potential channel 6 0.0025 0.0001 0.0001
Echinococcus multilocularis conserved hypothetical protein 0.1539 0.419 0.5188
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.006 0.0096 0.0096
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0266 0.0668 0.2188
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0025 0 0.00000098352
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.01 0.0208 0.0208
Brugia malayi Blistered cuticle protein 3 0.0078 0.0147 0.043
Schistosoma mansoni amine GPCR 0.1242 0.3368 0.417
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0128 0.0285 0.0353
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0303
Brugia malayi hypoxia-induced factor 1 0.0647 0.172 0.5047
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0208 0.0752
Echinococcus multilocularis serotonin receptor 0.0406 0.1053 0.1303
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0054 0.0081 0.0289
Echinococcus granulosus TRP transient receptor potential channel 0.0025 0 0.00000098352
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0112 0.0241 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0081 0.0289
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0063 0.0104 0.0372
Onchocerca volvulus Neuropeptide F receptor homolog 0.0134 0.0301 0.1095
Loa Loa (eye worm) G-protein coupled receptor 0.0134 0.0301 0.0882
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0019 0.0066
Trypanosoma brucei cytochrome P450, putative 0.0085 0.0165 0.0165
Echinococcus granulosus survival motor neuron protein 1 0.0776 0.2077 0.2572
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0199 0.0482 0.0482
Schistosoma mansoni inositol monophosphatase 0.0199 0.0482 0.0597
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.001 0.0009
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.0128 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0024 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0024 0.0081
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0199 0.0482 0.722
Brugia malayi hypothetical protein 0.0134 0.0301 0.0882
Onchocerca volvulus 0.0057 0.0089 0.0323
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Leishmania major calcium channel protein, putative,ion transporter, putative 0.026 0.065 0.065
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0025 0 0.00000098352
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0025 0 0.00000098352
Echinococcus granulosus carboxylesterase 5A 0.037 0.0955 0.1182
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.01 0.0208 0.3105
Schistosoma mansoni lozenge 0.006 0.0096 0.0118
Trypanosoma brucei C-8 sterol isomerase, putative 0.0821 0.2203 0.2203
Schistosoma mansoni ankyrin 23/unc44 0.0033 0.0021 0.0025
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0 0.00000098352
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0013 0.0016
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.026 0.0321
Brugia malayi bHLH-PAS transcription factor 0.0155 0.0358 0.1051
Mycobacterium ulcerans flavoprotein disulfide reductase 0.1004 0.2708 1
Brugia malayi Cytochrome P450 family protein 0.0085 0.0165 0.0483
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0083 0.0296
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0025 0.0001 0.0001
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0134 0.0301 0.0882
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0054 0.0081 0.01
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0024 0.0081
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0303
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0134 0.0301 0.0372
Echinococcus multilocularis lysine specific demethylase 5A 0.0064 0.0109 0.0134
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0199 0.048 0.1408
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0134 0.0301 0.0372
Leishmania major dihydrolipoamide dehydrogenase, putative 0.1004 0.2708 0.2708
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.01 0.0208 0.0208
Onchocerca volvulus Netrin receptor homolog 0.0033 0.0021 0.0074
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0067 0.0115 0.042
Trichomonas vaginalis mercuric reductase, putative 0.1004 0.2708 0.9864
Brugia malayi sulfakinin receptor protein 0.0134 0.0301 0.0882
Onchocerca volvulus 0.0134 0.0301 0.1095
Entamoeba histolytica hypothetical protein 0.0028 0.0009 0.0117
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0142 0.0176
Entamoeba histolytica hypothetical protein 0.0043 0.0051 0.0748
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0013 0.0038
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.0128 0.0158
Echinococcus granulosus intermediate filament protein 0.0061 0.01 0.0123
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.01 0.0208 0.0208
Brugia malayi hypothetical protein 0.0043 0.0051 0.0148
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0025 0 0.00000098352
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0036 0.003 0.0037
Schistosoma mansoni neuropeptide receptor 0.0134 0.0301 0.0372
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0013 0.0016
Echinococcus granulosus potassium voltage gated channel protein 0.0025 0 0.00000098352
Schistosoma mansoni hypothetical protein 0.0158 0.0368 0.0456
Loa Loa (eye worm) hypothetical protein 0.0057 0.0089 0.026
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0013 0.0016
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0025 0 0.00000098352
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1981 0.5412 0.6702
Brugia malayi Death domain containing protein 0.0033 0.0021 0.006
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0177 0.0421 0.1236
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0303
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.026 0.0762
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus sodium and chloride dependent glycine 0.0057 0.0089 0.011
Loa Loa (eye worm) doublecortin family protein 0.013 0.029 0.085
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0081 0.0289
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0036 0.003 0.0037
Toxoplasma gondii Erv1 / Alr family protein 0.0075 0.0139 0.0408
Echinococcus multilocularis neuropeptide Y receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) thioredoxin reductase 0.1257 0.3407 1
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0033 0.0021 0.0026
Echinococcus multilocularis neuropeptide s receptor 0.0629 0.167 0.2067
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0034 0.0024 0.0023
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0112 0.0241 0.0241
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.006 0.0096 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0241 0.0875
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus tm gpcr rhodopsin 0.0134 0.0301 0.0372
Schistosoma mansoni disulfide oxidoreductase 0.0266 0.0668 0.0827
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0097 0.0284
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.026 0.0321
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0266 0.0668 0.0667
Onchocerca volvulus 0.1018 0.2746 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0134 0.0301 0.0882
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0199 0.048 0.177
Loa Loa (eye worm) hypothetical protein 0.0029 0.0012 0.0035
Echinococcus granulosus arachidonate 5 lipoxygenase 0.05 0.1314 0.1627
Brugia malayi intermediate filament protein 0.0061 0.01 0.0291
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0057 0.0089 0.026
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0266 0.0668 0.0827
Schistosoma mansoni lipoxygenase 0.0266 0.0667 0.0826
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.1004 0.2708 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0021 0.0061
Brugia malayi hypothetical protein 0.0122 0.0267 0.0783
Echinococcus granulosus ATP binding cassette sub family G 0.0025 0.0001 0.0001
Onchocerca volvulus 0.0134 0.0301 0.1095
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Onchocerca volvulus 0.0063 0.0104 0.0376
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0057 0.0089 0.011
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0063 0.0104 0.0128
Plasmodium falciparum glutathione reductase 0.1257 0.3407 1
Echinococcus granulosus sex peptide receptor 0.0134 0.0301 0.0372
Schistosoma mansoni voltage-gated ion channel 0.0025 0 0.00000098352
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0009 0.0026
Onchocerca volvulus 0.0134 0.0301 0.1095
Echinococcus multilocularis hyperpolarization activated cyclic 0.0036 0.003 0.0037
Trichomonas vaginalis spcc417.12 protein, putative 0.0063 0.0104 0.0372
Loa Loa (eye worm) carboxylesterase 0.037 0.0955 0.2801
Schistosoma mansoni calcium-activated potassium channel 0.0025 0 0.00000098352
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0137 0.0493
Echinococcus multilocularis g protein coupled receptor 0.0134 0.0301 0.0372
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0266 0.0668 0.0827
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.01 0.0208 0.0257
Echinococcus granulosus alpha 1A adrenergic receptor 0.0134 0.0301 0.0372
Echinococcus granulosus acetylcholinesterase 0.037 0.0955 0.1182
Echinococcus granulosus microtubule associated protein 2 0.2944 0.8076 1
Echinococcus granulosus ATP binding cassette sub family G 0.0025 0.0001 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0572 0.1514 0.5512
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0134 0.0301 0.0372
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0075 0.0139 0.0139
Onchocerca volvulus 0.0155 0.0358 0.1304
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0101 0.021 0.026
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0191 0.0458 0.1319
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0001 0.0002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1238 0.3357 1
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0057 0.0089 0.0258
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0112 0.0241 0.0708
Loa Loa (eye worm) hypothetical protein 0.0693 0.1849 0.5425
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0025 0 0.00000098352
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1004 0.2708 0.2708
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0134 0.0301 0.0372
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.1004 0.2708 0.7947
Onchocerca volvulus 0.0266 0.0668 0.2431
Echinococcus multilocularis transfer RNA-Gly 0.0025 0 0.00000098352
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0013 0.0048
Schistosoma mansoni lipoxygenase 0.05 0.1314 0.1627
Echinococcus multilocularis 0.0067 0.0115 0.0142
Brugia malayi Thioredoxin reductase 0.1257 0.3407 1
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus multilocularis potassium voltage gated channel protein 0.0025 0 0.00000098352
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0075 0.0139 0.0139
Echinococcus granulosus lamin 0.0061 0.01 0.0123
Plasmodium vivax amine transporter, putative 0.0057 0.0089 0.0258
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0036 0.003 0.0037
Echinococcus granulosus potassium voltage gated channel protein 0.0025 0 0.00000098352
Plasmodium vivax multidomain scavenger receptor, putative 0.013 0.029 0.0848
Loa Loa (eye worm) hypothetical protein 0.1057 0.2857 0.8383
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0371 0.0958 0.1186
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0092 0.0329
Brugia malayi glutamate synthase 0.0266 0.0668 0.1959
Echinococcus granulosus jun protein 0.0371 0.0958 0.1186
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0266 0.0668 0.0667
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1238 0.3357 0.9851
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0668 0.2428
Echinococcus granulosus chromobox protein 1 0.0089 0.0176 0.0217
Echinococcus granulosus transient receptor potential cation channel 0.0025 0 0.000001021
Schistosoma mansoni amine GPCR 0.0134 0.0301 0.0372
Echinococcus multilocularis somatostatin receptor 0.0134 0.0301 0.0372
Schistosoma mansoni hypothetical protein 0.0067 0.0115 0.0142
Echinococcus multilocularis neuropeptide Y receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0821 0.2203 0.6466
Onchocerca volvulus 0.0054 0.0081 0.0293
Brugia malayi Carboxylesterase family protein 0.037 0.0955 0.2801
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0063 0.0104 0.0276
Trichomonas vaginalis set domain proteins, putative 0.1017 0.2745 1
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0025 0.0001 0.0002
Brugia malayi hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus mitogen activated protein kinase 3 0.0112 0.0241 0.0299
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0501 0.1317 0.3904
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0067 0.0115 0.0114
Echinococcus multilocularis neuropeptide receptor 0.0134 0.0301 0.0372
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0063 0.0104 0.0128
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0134 0.0301 0.0882
Loa Loa (eye worm) hypothetical protein 0.0025 0 0.000000088734
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0668 0.2428
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0081 0.0289
Plasmodium vivax ataxin-2 like protein, putative 0.0056 0.0086 0.025
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0036 0.003 0.0037
Schistosoma mansoni vesicular amine transporter 0.0025 0 0.00000098352
Echinococcus multilocularis sodium channel protein 0.026 0.065 0.0805
Brugia malayi bZIP transcription factor family protein 0.0371 0.0958 0.281
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.037 0.0955 0.1182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Echinococcus multilocularis calcium activated potassium channel 0.0026 0.0003 0.0003
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0042 0.0046 0.0045
Loa Loa (eye worm) hypothetical protein 0.1057 0.2857 0.8383
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.0128 0.0158
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0013 0.0038
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0112 0.0241 0.0241
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0096 0.0346
Schistosoma mansoni neuropeptide receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0013 0.0038
Echinococcus multilocularis voltage gated potassium channel 0.0043 0.0051 0.0062
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0109 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0013 0.0038
Brugia malayi jmjC domain containing protein 0.0064 0.0109 0.0318
Schistosoma mansoni growth hormone secretagogue receptor 0.0134 0.0301 0.0372
Schistosoma mansoni opsin-like receptor 0.0134 0.0301 0.0372
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.1004 0.2708 0.3353
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0095 0.034
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) hepatopoietin HPO2 0.0075 0.0139 0.0408
Echinococcus multilocularis lamin 0.0061 0.01 0.0123
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0134 0.0301 0.0372
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0191 0.0458 0.0567
Onchocerca volvulus 0.0134 0.0301 0.1095
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0013 0.0016
Brugia malayi chromobox protein homolog 3 0.0055 0.0083 0.0242
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.026 0.0736
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0241 0.0875
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.1004 0.2708 0.7942
Echinococcus granulosus rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0134 0.0301 0.0372
Trichomonas vaginalis glucosylceramidase, putative 0.0572 0.1514 0.5512
Schistosoma mansoni biogenic amine (5HT) receptor 0.0134 0.0301 0.0372
Echinococcus multilocularis ATP binding cassette sub family G 0.0025 0.0001 0.0001
Echinococcus multilocularis Ankyrin 0.0033 0.0021 0.0026
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0668 0.2428
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Loa Loa (eye worm) runx1 0.006 0.0096 0.028
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0959 0.2814
Mycobacterium leprae Conserved hypothetical protein 0.0067 0.0115 0.0313
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.026 0.0894
Echinococcus multilocularis shaker cognate 0.0025 0 0.00000098352
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0001 0.0001
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0266 0.0668 0.2428
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0063 0.0104 0.0276
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0063 0.0104 0.0128
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0013 0.0016
Echinococcus granulosus BC026374 protein S09 family 0.0063 0.0104 0.0128
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0057 0.0089 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.0375 0.0969 0.3528
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0025 0 0.00000098352
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0019 0.0056
Loa Loa (eye worm) hypothetical protein 0.0034 0.0023 0.0067
Loa Loa (eye worm) blistered cuticle protein 3 0.0078 0.0147 0.043
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0501 0.1317 0.3846
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0137 0.0493
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0199 0.0482 0.0482
Loa Loa (eye worm) hypothetical protein 0.006 0.0097 0.0284
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.001 0.0033
Echinococcus granulosus neuroligin 0.0063 0.0104 0.0128
Echinococcus granulosus transient receptor potential cation channel 0.0025 0 0.00000098352
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0033 0.0021 0.0025
Echinococcus granulosus mitogen activated protein kinase 0.0112 0.0241 0.0299
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0051 0.0062
Leishmania major ferric reductase, putative 0.0037 0.0032 0.0032
Echinococcus granulosus g protein coupled receptor 0.0134 0.0301 0.0372
Leishmania major cytochrome p450-like protein 0.0085 0.0165 0.0165
Schistosoma mansoni loxhd1 0.013 0.029 0.0359
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.026 0.026
Echinococcus multilocularis orexin receptor type 2 0.0134 0.0301 0.0372
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0013 0.0038
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0266 0.0668 1
Echinococcus multilocularis voltage gated potassium channel 0.0025 0 0.00000098352
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0101 0.021 0.026
Schistosoma mansoni hypothetical protein 0.0134 0.0301 0.0372
Onchocerca volvulus 0.0121 0.0266 0.0969
Loa Loa (eye worm) hypothetical protein 0.0035 0.0027 0.0078
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0266 0.0668 0.1959
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0142 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0081 0.0289
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.026 0.026
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0025 0.0001 0.0001
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.1004 0.2708 0.2708
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0038
Trypanosoma brucei target of rapamycin kinase 3, putative 0.008 0.0151 0.0151
Brugia malayi 6-phosphofructokinase 0.0119 0.0261 0.0764
Trichomonas vaginalis glucosylceramidase, putative 0.0375 0.0969 0.3528
Echinococcus granulosus neuropeptide s receptor 0.0629 0.167 0.2067
Trypanosoma cruzi cytochrome P450, putative 0.0085 0.0165 0.0165
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) phosphatidylinositol 3 0.01 0.0208 0.0609
Loa Loa (eye worm) hypothetical protein 0.0057 0.0089 0.026
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0067 0.0115 0.0114
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0067 0.0115 0.042
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0075 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0303
Echinococcus multilocularis rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0019 0.0055
Echinococcus granulosus sodium leak channel non selective protein 0.0025 0 0.00000098352
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.001 0.0033
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1004 0.2708 1
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0083 0.0296
Loa Loa (eye worm) G-protein coupled receptor 0.0134 0.0301 0.0882
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0013 0.0016
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0054 0.0081 0.0228
Onchocerca volvulus 0.0476 0.1248 0.4545
Echinococcus multilocularis neuropeptides capa receptor 0.0134 0.0301 0.0372
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0013 0.0016
Brugia malayi Cytochrome P450 family protein 0.0085 0.0165 0.0483
Brugia malayi Augmenter of liver regeneration 0.0075 0.0139 0.0408
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0112 0.0241 0.0708
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0.0001 0.0001
Treponema pallidum exodeoxyribonuclease (exoA) 0.006 0.0096 0.0286
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0266 0.0668 0.0827
Schistosoma mansoni amine GPCR 0.0134 0.0301 0.0372
Onchocerca volvulus 0.0061 0.01 0.0361
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0063 0.0104 0.0128
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0064 0.0109 0.0134
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0067 0.0115 0.0309
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0025 0 0.00000098352
Brugia malayi steroid hormone receptor 0.003 0.0013 0.0038
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0266 0.0668 0.0827
Onchocerca volvulus 0.0063 0.0104 0.0376
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0067 0.0115 0.042
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0001 0.0005
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0158 0.0368 0.108
Echinococcus granulosus neuropeptides capa receptor 0.0134 0.0301 0.0372
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.2671 0.7322 0.7322
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0036 0.003 0.0037
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0037 0.0032 0.0032
Trypanosoma brucei ferric reductase transmembrane protein, putative 0.0037 0.0032 0.0032
Plasmodium falciparum thioredoxin reductase 0.1257 0.3407 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0199 0.0482 0.0482
Plasmodium falciparum ferrodoxin reductase-like protein 0.0266 0.0668 0.1958
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0086 0.025
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0266 0.0668 0.2188
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0013 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0151 0.0546
Onchocerca volvulus 0.0337 0.0863 0.3143
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0266 0.0668 0.1959
Loa Loa (eye worm) carboxylesterase 0.0063 0.0104 0.0303
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0045 0.0055
Echinococcus multilocularis potassium voltage gated channel protein 0.0025 0 0.00000098352
Schistosoma mansoni amine GPCR 0.0134 0.0301 0.0372
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.026 0.0321
Schistosoma mansoni hypothetical protein 0.0041 0.0044 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0013 0.0038
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0067 0.0115 0.0309
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0027 0.0033
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0266 0.0668 0.0667
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0179 0.0425 0.1239
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0303
Trichomonas vaginalis glucosylceramidase, putative 0.0375 0.0969 0.3528
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0142 0.0176
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0134 0.0301 0.0372
Trypanosoma cruzi hypothetical protein, conserved 0.0266 0.0668 0.0667
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0303
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0067 0.0115 0.042
Brugia malayi G-protein coupled receptor 0.0134 0.0301 0.0882
Schistosoma mansoni hypothetical protein 0.0043 0.0051 0.0062
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0266 0.0668 0.0827
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0097 0.0284
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0025 0 0.00000098352
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0266 0.0668 0.1958
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0025 0 0.00000098352
Onchocerca volvulus 0.0134 0.0301 0.1095
Schistosoma mansoni rab6-interacting 0.013 0.029 0.0359
Echinococcus granulosus potassium voltage gated channel protein 0.0025 0 0.00000098352
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0055 0.0084 0.0083
Echinococcus granulosus acetylcholinesterase 0.037 0.0955 0.1182
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0128 0.0285 0.0353
Plasmodium vivax importin-beta 2, putative 0.0035 0.0027 0.0076
Schistosoma mansoni lamin 0.0061 0.01 0.0123
Loa Loa (eye worm) hypothetical protein 0.0033 0.0021 0.0062
Mycobacterium leprae putative cytochrome p450 0.0067 0.0115 0.0313
Loa Loa (eye worm) hypothetical protein 0.0701 0.187 0.5488
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0134 0.0301 0.0882
Echinococcus multilocularis potassium large conductance calcium activated 0.0025 0 0.00000098352
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0033 0.0021 0.006
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus snurportin 1 0.0372 0.0959 0.1187
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0266 0.0668 0.1937
Brugia malayi MAP kinase sur-1 0.0112 0.0241 0.0708
Brugia malayi glutathione reductase 0.1257 0.3407 1
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0054 0.0081 0.01
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0134 0.0301 0.0372
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0036 0.003 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.006 0.0096 0.0119
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0266 0.0668 0.0827
Schistosoma mansoni sodium/chloride dependent transporter 0.0057 0.0089 0.011
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0266 0.0668 0.0667
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.026 0.0942
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.3059 0.8396 0.8396
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0191 0.0458 0.0567
Toxoplasma gondii aldehyde dehydrogenase 0.0191 0.0458 0.1343
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0025 0 0.00000098352
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0067 0.0115 0.042
Onchocerca volvulus 0.013 0.029 0.1054
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0025 0 0.00000098352
Echinococcus granulosus cytochrome P450 2K1 0.0067 0.0115 0.0142
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0057 0.0089 0.011
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0266 0.0668 0.1959
Trichomonas vaginalis inositol monophosphatase, putative 0.0199 0.0482 0.1753
Echinococcus multilocularis two pore calcium channel protein 2 0.0025 0 0.00000098352
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.0128 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0151 0.0546
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.001 0.0033
Trypanosoma brucei NADH dehydrogenase 0.0266 0.0668 0.0667
Schistosoma mansoni hypothetical protein 0.0134 0.0301 0.0372
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0043 0.0051 0.0148
Echinococcus granulosus sodium channel protein 0.026 0.065 0.0805
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.003 0.0104
Echinococcus multilocularis Protein lozenge 0.006 0.0096 0.0118
Onchocerca volvulus 0.0134 0.0301 0.1095
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0101 0.021 0.0616
Loa Loa (eye worm) hypothetical protein 0.006 0.0096 0.0282
Onchocerca volvulus 0.0292 0.0737 0.2684
Trypanosoma cruzi NADH dehydrogenase, putative 0.0266 0.0668 0.0667
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0266 0.0668 0.0827
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0013 0.0048
Schistosoma mansoni 60S ribosomal protein L21 0.0033 0.0021 0.0026
Trichomonas vaginalis glucosylceramidase, putative 0.0572 0.1514 0.5512
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0019 0.0066
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.026 0.0942
Echinococcus granulosus aryl hydrocarbon receptor 0.0054 0.0081 0.01
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.01 0.0208 0.0208
Brugia malayi ecdysteroid receptor 0.003 0.0013 0.0038
Loa Loa (eye worm) hypothetical protein 0.0476 0.1248 0.3663
Mycobacterium ulcerans aldehyde dehydrogenase 0.0191 0.0458 0.1688
Toxoplasma gondii hypothetical protein 0.0057 0.0089 0.026
Echinococcus granulosus death domain containing protein 0.0033 0.0021 0.0025
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0128 0.0128
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0134 0.0301 0.0372
Leishmania major hypothetical protein, conserved 0.0266 0.0668 0.0667
Schistosoma mansoni biogenic amine receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypoxia-induced factor 1 0.0647 0.172 0.5047
Brugia malayi TAR-binding protein 0.0076 0.0142 0.0416
Loa Loa (eye worm) hypothetical protein 0.0128 0.0285 0.0836
Echinococcus granulosus rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0142 0.0416
Onchocerca volvulus 0.0054 0.008 0.0289
Loa Loa (eye worm) solute carrier family 6 member 4 0.0337 0.0863 0.2533
Schistosoma mansoni inositol monophosphatase 0.0199 0.0482 0.0597
Echinococcus multilocularis sex peptide receptor 0.0134 0.0301 0.0372
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0097 0.0198 0.0245
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0266 0.0668 0.1937
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0025 0 0.00000098352
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.01 0.0208 0.0208
Trypanosoma cruzi trypanothione reductase, putative 0.1257 0.3407 0.3407
Leishmania major protein kinase, putative 0.0055 0.0084 0.0083
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.001 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0013 0.0038
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0067 0.0115 0.042
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0054 0.0081 0.0236
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0054 0.0081 0.0289
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.006 0.0096 0.0096
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.1004 0.2708 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0096 0.0346
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0025 0 0.00000098352
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0067 0.0115 0.0309
Echinococcus granulosus two pore calcium channel protein 2 0.0025 0 0.00000098352
Onchocerca volvulus Dual oxidase homolog 0.0078 0.0147 0.0533
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0109 0.0134
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0036 0.003 0.0087
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0241 0.0875
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0057 0.0089 0.011
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0038
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0013 0.0016
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0737 0.1971 0.5783
Echinococcus granulosus neuropeptide receptor 0.0134 0.0301 0.0372
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0266 0.0668 0.1959
Trypanosoma cruzi hypothetical protein, conserved 0.0266 0.0668 0.0667
Schistosoma mansoni aryl hydrocarbon receptor 0.0209 0.0509 0.063
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0075 0.0139 0.0407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.008 0.0287
Loa Loa (eye worm) hypothetical protein 0.0122 0.0267 0.0783
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0025 0 0.00000098352
Schistosoma mansoni voltage-gated cation channel 0.0025 0 0.00000098352
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0266 0.0668 0.0667
Echinococcus multilocularis sodium and chloride dependent glycine 0.0057 0.0089 0.011
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0014 0.0047
Leishmania major hypothetical protein, conserved 0.0266 0.0668 0.0667
Brugia malayi Melatonin receptor type 1A 0.0134 0.0301 0.0882
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0067 0.0115 0.042
Schistosoma mansoni hypothetical protein 0.0033 0.0021 0.0025
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0134 0.0301 0.0882
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0013 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0013 0.0038
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.026 0.065 0.0805
Trichomonas vaginalis PIKK family atypical protein kinase 0.0067 0.0117 0.042
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0013 0.0016
Echinococcus granulosus sodium and chloride dependent glycine 0.0057 0.0089 0.011
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0266 0.0668 0.1966
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0055 0.0083 0.03
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0019 0.028
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.001 0.0009
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0199 0.0482 0.1753
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0151 0.0546
Echinococcus granulosus voltage gated potassium channel 0.0043 0.0051 0.0062
Brugia malayi Intermediate filament tail domain containing protein 0.0061 0.01 0.0291
Schistosoma mansoni amine GPCR 0.0134 0.0301 0.0372
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0142 0.0416
Loa Loa (eye worm) hypothetical protein 0.0025 0 0.000000088734
Trichomonas vaginalis glucosylceramidase, putative 0.0375 0.0969 0.3528
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0054 0.0081 0.0289
Echinococcus multilocularis acetylcholinesterase 0.037 0.0955 0.1182
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.2671 0.7322 0.7322
Echinococcus granulosus glutamate synthase 0.0266 0.0668 0.0827
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0134 0.0301 0.0882
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0064 0.0109 0.0134
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0025 0 0.00000098352
Schistosoma mansoni biogenic amine (5HT) receptor 0.0406 0.1053 0.1303
Brugia malayi Serotonin receptor 0.116 0.3141 0.9217
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0038
Treponema pallidum NADH oxidase 0.1004 0.2708 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0084 0.0083
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0572 0.1514 0.4442
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.001 0.0134
Leishmania major phosphatidylinositol 3-kinase, putative 0.0034 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0055 0.0083 0.0242
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0085 0.0165 0.0606
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0337 0.0863 0.1069
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0191 0.0458 0.0458
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.003 0.0104
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0142 0.0416
Echinococcus multilocularis serotonin receptor 0.0406 0.1053 0.1303
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0101 0.021 0.0616
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0266 0.0668 0.1966
Onchocerca volvulus 0.0134 0.0301 0.1095
Mycobacterium leprae Possible regulatory protein 0.0054 0.0081 0.0212
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0134 0.0301 0.0372
Loa Loa (eye worm) heterochromatin protein 1 0.0089 0.0176 0.0514
Brugia malayi follicle stimulating hormone receptor 0.0385 0.0995 0.2919
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.1004 0.2708 0.7947
Onchocerca volvulus 0.0134 0.0301 0.1095
Loa Loa (eye worm) glutathione reductase 0.1257 0.3407 1
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.026 0.3883
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Echinococcus granulosus inositol monophosphatase 1 0.0199 0.0482 0.0597
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0266 0.0668 0.0667
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0134 0.0301 0.0372
Echinococcus granulosus Polycystic kidney disease protein 0.013 0.029 0.0359
Mycobacterium ulcerans ferredoxin reductase 0.0266 0.0668 0.2464
Trypanosoma brucei trypanothione reductase 0.1257 0.3407 0.3407
Echinococcus multilocularis neuroligin 0.0063 0.0104 0.0128
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0337 0.0863 0.2533
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0013 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0013 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0013 0.0038
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0501 0.1317 0.3846
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0009 0.0008
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0057 0.0089 0.026
Schistosoma mansoni glutamate synthase 0.0266 0.0668 0.0827
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0134 0.0301 0.0372
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0067 0.0115 0.042
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0134 0.0301 0.0372
Echinococcus granulosus transient receptor potential cation channel 0.0025 0 0.000001021
Echinococcus multilocularis g protein coupled receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0476 0.1248 0.3663
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0123 0.0272 0.0337
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0057 0.0089 0.026
Schistosoma mansoni alpha-1 adrenergic receptor 0.0134 0.0301 0.0372
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0014 0.0047
Echinococcus granulosus tachykinin peptides receptor 99D 0.0134 0.0301 0.0372
Echinococcus granulosus g-protein coupled receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0036 0.003 0.0037
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0067 0.0115 0.042
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0027 0.0027
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.006 0.0096 0.0255
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0266 0.0668 0.2464
Echinococcus granulosus tm gpcr rhodopsin 0.0134 0.0301 0.0372
Mycobacterium ulcerans putative regulatory protein 0.0155 0.0358 0.1321
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.006 0.0096 0.028
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0045 0.0055
Schistosoma mansoni cytochrome P450 0.0067 0.0115 0.0142
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0025 0 0.00000098352
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Plasmodium falciparum thioredoxin reductase 0.1004 0.2708 0.7947
Trypanosoma cruzi ferric reductase transmembrane protein, putative 0.0037 0.0032 0.0032
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0057 0.0089 0.026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.006 0.0096 0.0096
Loa Loa (eye worm) cytochrome P450 family protein 0.0085 0.0165 0.0483
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0058 0.0092 0.0333
Echinococcus multilocularis lipoxygenase domain containing protein 0.013 0.029 0.0359
Schistosoma mansoni adenoreceptor 0.0134 0.0301 0.0372
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0821 0.2203 0.6466
Mycobacterium ulcerans aldehyde dehydrogenase 0.0191 0.0458 0.1688
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0199 0.0482 0.1478
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0026
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0128 0.0128
Echinococcus granulosus neuropeptide receptor A26 0.0629 0.167 0.2067
Treponema pallidum sodium- and chloride- dependent transporter 0.0337 0.0863 0.3138
Schistosoma mansoni voltage-gated potassium channel 0.0108 0.0231 0.0285
Loa Loa (eye worm) CYP4Cod1 0.0085 0.0165 0.0483
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0089 0.0258
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.026 0.0957
Loa Loa (eye worm) hypothetical protein 0.0041 0.0045 0.0132
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0067 0.0115 0.042
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0038
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0025 0 0.00000098352
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0266 0.0668 0.0827
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0038
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0075 0.0139 0.0139
Echinococcus granulosus peptide allatostatin:somatostatin 0.0134 0.0301 0.0372
Schistosoma mansoni biogenic amine receptor 0.0134 0.0301 0.0372
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3059 0.8396 0.8396
Schistosoma mansoni transient receptor potential channel 0.0025 0.0001 0.0001
Onchocerca volvulus 0.0134 0.0301 0.1095
Plasmodium vivax thioredoxin reductase, putative 0.1257 0.3407 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0034 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0134 0.0301 0.0372
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0019 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0013 0.0038
Brugia malayi hypothetical protein 0.0134 0.0301 0.0882
Loa Loa (eye worm) cytochrome P450 0.0067 0.0115 0.0335
Schistosoma mansoni lamin 0.0061 0.01 0.0123
Loa Loa (eye worm) hypothetical protein 0.0057 0.0089 0.026
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0036 0.003 0.0037
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0266 0.0668 1
Mycobacterium ulcerans NADH dehydrogenase 0.0266 0.0668 0.2464
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0013 0.0016
Brugia malayi Carboxylesterase family protein 0.037 0.0955 0.2801
Schistosoma mansoni acetylcholinesterase 0.0063 0.0104 0.0128
Trypanosoma brucei ABC transporter, putative 0.0025 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0337 0.0863 0.2533
Trypanosoma cruzi ABC transporter, putative 0.0025 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0134 0.0301 0.0372
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1238 0.3357 0.9851
Loa Loa (eye worm) hypothetical protein 0.0057 0.0089 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0137 0.0493
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0019 0.0066
Echinococcus granulosus ATP binding cassette sub family G 0.0025 0.0001 0.0001
Schistosoma mansoni netrin receptor unc5 0.0033 0.0021 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.008 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.01 0.0208 0.0752
Onchocerca volvulus 0.0158 0.0368 0.134
Echinococcus granulosus orexin receptor type 2 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0028 0.0009 0.0026
Echinococcus granulosus histone lysine methyltransferase setb 0.0128 0.0285 0.0353
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.05 0.1314 0.1627
Trichomonas vaginalis ap endonuclease, putative 0.006 0.0096 0.0346
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Schistosoma mansoni sulfide quinone reductase 0.0266 0.0668 0.0827
Echinococcus granulosus thioredoxin glutathione reductase 0.1257 0.3407 0.4219
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.006 0.0096 0.0119
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0266 0.0668 0.0667
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0266 0.0668 0.2464
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0025 0 0.00000098352
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0019 0.0055
Echinococcus granulosus allatostatin A receptor 0.0134 0.0301 0.0372
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0067 0.0115 0.0309
Brugia malayi Cytochrome P450 family protein 0.0127 0.0281 0.0824
Schistosoma mansoni ap endonuclease 0.006 0.0096 0.0119
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0134 0.0301 0.1095
Echinococcus multilocularis para nitrobenzyl esterase 0.0063 0.0104 0.0128
Toxoplasma gondii LsmAD domain-containing protein 0.0056 0.0086 0.0252
Entamoeba histolytica disulphide oxidoreductase, putative 0.0266 0.0668 1
Loa Loa (eye worm) hypothetical protein 0.0361 0.093 0.2728
Loa Loa (eye worm) hypothetical protein 0.042 0.1092 0.3205
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0057 0.0089 0.026
Chlamydia trachomatis thioredoxin reductase 0.0266 0.0668 0.2411
Echinococcus multilocularis tumor protein p63 0.0368 0.095 0.1176
Echinococcus granulosus tar DNA binding protein 0.0076 0.0142 0.0176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0134 0.0301 0.0372
Plasmodium falciparum importin beta, putative 0.0035 0.0027 0.0076
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0013 0.0038
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0025 0 0.00000098352
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0266 0.0668 0.0667
Mycobacterium tuberculosis Probable oxidoreductase 0.1238 0.3357 0.9851
Loa Loa (eye worm) serotonin transporter b 0.0337 0.0863 0.2533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0024 0.0081
Giardia lamblia NADH oxidase lateral transfer candidate 0.1004 0.2708 1
Trichomonas vaginalis apoptosis inducing factor, putative 0.0266 0.0668 0.2428
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0019 0.0055
Treponema pallidum oxidoreductase 0.0266 0.0668 0.2411
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.1004 0.2708 0.2708
Schistosoma mansoni sodium/chloride dependent transporter 0.0337 0.0863 0.1069
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0266 0.0668 0.0667
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.026 0.026
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0081 0.008
Onchocerca volvulus 0.003 0.0013 0.0048
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.1004 0.2708 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.008 0.0287
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0036 0.003 0.0037
Schistosoma mansoni hypothetical protein 0.0722 0.1928 0.2387
Entamoeba histolytica exodeoxyribonuclease III, putative 0.006 0.0096 0.1431
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0112 0.0241 0.0241
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0266 0.0668 0.1966
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0501 0.1317 0.3846
Leishmania major C-8 sterol isomerase-like protein 0.0821 0.2203 0.2203
Trichomonas vaginalis glucosylceramidase, putative 0.0572 0.1514 0.5512
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Brugia malayi SET domain containing protein 0.0029 0.0012 0.0034
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0025 0 0.00000098352
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0067 0.0115 0.0309
Echinococcus multilocularis aryl hydrocarbon receptor 0.0054 0.0081 0.01
Schistosoma mansoni neuroligin 3 (S09 family) 0.0063 0.0104 0.0128
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0025 0 0.00000098352
Echinococcus multilocularis rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0027 0.0027
Mycobacterium tuberculosis Probable dehydrogenase 0.0501 0.1317 0.3846
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0134 0.0301 0.0372
Echinococcus granulosus voltage gated hydrogen channel 1 0.0025 0 0.00000098352
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0176 0.0634
Schistosoma mansoni ran 0.0026 0.0001 0.0001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0013 0.0016
Brugia malayi Cytochrome P450 family protein 0.0067 0.0115 0.0335
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0266 0.0668 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0148
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0266 0.0668 0.1966
Loa Loa (eye worm) phosphofructokinase 0.0119 0.026 0.0762
Echinococcus granulosus lipoxygenase domain containing protein 0.013 0.029 0.0359
Loa Loa (eye worm) hypothetical protein 0.037 0.0955 0.2801
Leishmania major GTP-binding protein, putative 0.0026 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0038
Echinococcus granulosus neuropeptide Y receptor 0.0134 0.0301 0.0372
Trichomonas vaginalis guanylate cyclase, putative 0.0054 0.0081 0.0289
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0067 0.0115 0.0114
Echinococcus granulosus calcium activated potassium channel 0.0026 0.0003 0.0003
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.0128 0.1905
Echinococcus granulosus somatostatin receptor 0.0134 0.0301 0.0372
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0199 0.0482 0.1753
Onchocerca volvulus 0.0153 0.0354 0.1287
Onchocerca volvulus 0.0134 0.0301 0.1095
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0051 0.0062
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0013 0.0016
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0134 0.0301 0.0372
Loa Loa (eye worm) inositol-1 0.0199 0.0482 0.1415
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0176 0.0634
Leishmania major cytochrome p450-like protein 0.0067 0.0115 0.0114
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0134 0.0301 0.0372
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0067 0.0115 0.042
Loa Loa (eye worm) hypothetical protein 0.0057 0.0089 0.026
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0266 0.0668 0.1959
Brugia malayi Pre-SET motif family protein 0.0894 0.2404 0.7054
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0266 0.0668 0.1959
Onchocerca volvulus 0.0057 0.0089 0.0323
Echinococcus granulosus neuropeptides capa receptor 0.0134 0.0301 0.0372
Echinococcus granulosus rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Onchocerca volvulus 0.0057 0.0089 0.0323
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0075 0.0139 0.0172
Echinococcus granulosus serotonin transporter 0.0337 0.0863 0.1069
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.001 0.0033
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0134 0.0301 0.0372
Plasmodium vivax SET domain protein, putative 0.0128 0.0285 0.0835
Loa Loa (eye worm) carboxylesterase 0.0063 0.0104 0.0303
Echinococcus multilocularis inositol monophosphatase 1 0.0199 0.0482 0.0597
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0199 0.0482 0.1415
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.3639 1 1
Brugia malayi hypothetical protein 0.0134 0.0301 0.0882
Brugia malayi hypothetical protein 0.0057 0.0089 0.026
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Brugia malayi AKH receptor 0.0134 0.0301 0.0882
Echinococcus granulosus transient receptor potential cation channel 0.0025 0 0.00000098352
Schistosoma mansoni single-minded 0.0209 0.0509 0.063
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0067 0.0115 0.0114
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0112 0.0241 0.0241
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.026 0.0747
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0057 0.0089 0.011
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0024 0.0068
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.1004 0.2708 0.3353
Trichomonas vaginalis glucosylceramidase, putative 0.0375 0.0969 0.3528
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0051 0.0062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0134 0.0301 0.0372
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0067 0.0115 0.042
Onchocerca volvulus 0.013 0.029 0.1054
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0025 0 0.00000098352
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0142 0.0176
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0019 0.0066
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0097 0.0284
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.0128 0.0374
Brugia malayi hypothetical protein 0.0063 0.0104 0.0303
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0001 0.0003
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0057 0.0089 0.026
Trichomonas vaginalis CMGC family protein kinase 0.0112 0.0241 0.0875
Brugia malayi nuclear hormone receptor 0.003 0.0013 0.0038
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0054 0.0081 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0396 0.1025 0.3732
Entamoeba histolytica thioredoxin reductase, putative 0.0266 0.0668 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.006 0.0096 0.0282
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0034 0.0024 0.0029
Mycobacterium ulcerans hypothetical protein 0.0029 0.001 0.0033
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0013 0.0016
Echinococcus granulosus hyperpolarization activated cyclic 0.0036 0.003 0.0037
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.026 0.0942
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0109 0.0134
Echinococcus granulosus neuropeptide FF receptor 2 0.0134 0.0301 0.0372
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0134 0.0301 0.0372
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0019 0.0066
Brugia malayi Doublecortin family protein 0.013 0.029 0.085
Brugia malayi hypothetical protein 0.0266 0.0666 0.1955
Brugia malayi Immunoglobulin I-set domain containing protein 0.0033 0.0021 0.006
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0021 0.0026
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0086 0.025
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0067 0.0115 0.0309
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0001 0.0001
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0266 0.0668 0.2464
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0057 0.0089 0.011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0051 0.0062
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0109 0.0318
Echinococcus granulosus two pore calcium channel protein 1 0.0025 0 0.00000098352
Echinococcus granulosus hyperpolarization activated cyclic 0.0036 0.003 0.0037
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0303
Echinococcus multilocularis glutamate synthase 0.0266 0.0668 0.0827
Loa Loa (eye worm) hypothetical protein 0.0041 0.0044 0.0129
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.006 0.0096 0.0355
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0266 0.0668 0.1959
Trypanosoma brucei protein kinase, putative 0.0112 0.0241 0.0241
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0009 0.0026
Onchocerca volvulus 0.0034 0.0023 0.0084
Echinococcus granulosus transient receptor potential cation channel 0.0025 0 0.00000098352
Trypanosoma brucei hypothetical protein, conserved 0.0266 0.0668 0.0667
Echinococcus granulosus 7TM GPCR rhodopsin 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0061 0.01 0.0291
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0134 0.0301 0.0372
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0013 0.0038
Echinococcus multilocularis fmrfamide receptor 0.0134 0.0301 0.0372
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0013 0.0016
Toxoplasma gondii hypothetical protein 0.0057 0.0089 0.026
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0199 0.048 0.1384
Schistosoma mansoni histamine h1 receptor 0.0134 0.0301 0.0372
Echinococcus granulosus biogenic amine 5HT receptor 0.0406 0.1053 0.1303
Schistosoma mansoni intermediate filament proteins 0.0061 0.01 0.0123
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0266 0.0668 0.2464
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0128 0.0285 0.0353
Echinococcus multilocularis allatostatin A receptor 0.0134 0.0301 0.0372
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0036 0.003 0.0037
Echinococcus multilocularis rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Brugia malayi larval opioid receptor 0.0134 0.0301 0.0882
Schistosoma mansoni aldehyde dehydrogenase 0.0191 0.0458 0.0567
Schistosoma mansoni voltage-gated potassium channel 0.0025 0 0.00000098352
Echinococcus multilocularis g protein coupled receptor 0.0134 0.0301 0.0372
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0076 0.014 0.0506
Entamoeba histolytica hypothetical protein 0.0043 0.0051 0.0748
Toxoplasma gondii selenide, water dikinase 0.0266 0.0668 0.1959
Loa Loa (eye worm) neuropeptide F receptor 0.0134 0.0301 0.0882
Echinococcus granulosus rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0021 0.0061
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0057 0.0089 0.011
Brugia malayi putative neuropeptide receptor NPR1 0.0134 0.0301 0.0882
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0067 0.0115 0.0309
Loa Loa (eye worm) cytochrome P450 family protein 0.0127 0.0281 0.0824
Echinococcus multilocularis neuropeptide receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) hypothetical protein 0.0054 0.0081 0.0236
Schistosoma mansoni coup transcription factor 0.003 0.0013 0.0016
Brugia malayi hypothetical protein 0.0776 0.2077 0.6095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0013 0.0038
Echinococcus multilocularis jun protein 0.0371 0.0958 0.1186
Echinococcus multilocularis short transient receptor potential channel 6 0.0025 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0013 0.0038
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.01 0.0208 0.0257
Plasmodium falciparum glutathione reductase 0.1004 0.2708 0.7947
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0067 0.0115 0.0309
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.1004 0.2708 0.3353
Echinococcus granulosus para nitrobenzyl esterase 0.0063 0.0104 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0054 0.0081 0.0289
Echinococcus multilocularis rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Brugia malayi ORL1-like opioid receptor 0.0134 0.0301 0.0882
Schistosoma mansoni ryanodine receptor related 0.0025 0 0.00000098352
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0013 0.0048
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0092 0.0329
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Schistosoma mansoni opsin-like receptor 0.0134 0.0301 0.0372
Echinococcus multilocularis lamin dm0 0.0061 0.01 0.0123
Mycobacterium ulcerans monoxygenase 0.0266 0.0668 0.2464
Trypanosoma cruzi cytochrome P450, putative 0.0085 0.0165 0.0165
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0025 0 0.00000098352
Schistosoma mansoni neuropeptide f receptor 76f 0.0134 0.0301 0.0372
Brugia malayi RNA, U transporter 1 0.0099 0.0204 0.0599
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0128 0.0285 0.0353
Echinococcus granulosus dro:myosuppressin receptor 0.0134 0.0301 0.0372
Trichomonas vaginalis PIKK family atypical protein kinase 0.0075 0.0137 0.0493
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.026 0.0762
Giardia lamblia Kinase, CMGC MAPK 0.0112 0.0241 0.0892
Schistosoma mansoni aldehyde dehydrogenase 0.0191 0.0458 0.0567
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0024 0.0081
Leishmania major hypothetical protein, conserved 0.0056 0.0086 0.0086
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.008 0.0098
Echinococcus multilocularis dro:myosuppressin receptor 0.0134 0.0301 0.0372
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.026 0.3883
Echinococcus multilocularis neuropeptides capa receptor 0.0134 0.0301 0.0372
Echinococcus multilocularis microtubule associated protein 2 0.2944 0.8076 1
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0013 0.0016
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.001 0.0134
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0067 0.0115 0.0309
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.01 0.0208 0.0609
Mycobacterium tuberculosis Probable reductase 0.0501 0.1317 0.3846
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.026 0.0321
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0067 0.0115 0.0309
Loa Loa (eye worm) hypothetical protein 0.0029 0.001 0.0028
Brugia malayi Uncoordinated protein 44 0.0033 0.0021 0.006
Toxoplasma gondii thioredoxin reductase 0.1257 0.3407 1
Brugia malayi putative neuropeptide receptor 0.0134 0.0301 0.0882
Brugia malayi Dopamine receptor protein 1 0.0134 0.0301 0.0882
Brugia malayi Inositol-1 0.0199 0.0482 0.1415
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0067 0.0115 0.0309
Brugia malayi G protein-coupled receptor 0.0134 0.0301 0.0882
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0067 0.0115 0.042
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.01 0.0208 0.0208
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0057 0.0089 0.011
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.026 0.0942
Brugia malayi hypothetical protein 0.0701 0.187 0.5488
Echinococcus multilocularis survival motor neuron protein 1 0.0776 0.2077 0.2572
Brugia malayi hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0134 0.0301 0.0372
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0067 0.0115 0.042
Schistosoma mansoni sodium/chloride dependent transporter 0.0058 0.0092 0.0113
Brugia malayi phosphofructokinase 0.0119 0.026 0.0762
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0153 0.0354 0.0438
Toxoplasma gondii NADPH-glutathione reductase 0.1004 0.2708 0.7947
Trichomonas vaginalis guanylate cyclase, putative 0.0054 0.0081 0.0289
Trypanosoma cruzi trypanothione reductase, putative 0.1004 0.2708 0.2708
Echinococcus granulosus tumor protein p63 0.0368 0.095 0.1176
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0179 0.0425 0.1221
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0075 0.0139 0.0407
Loa Loa (eye worm) hypothetical protein 0.013 0.029 0.085
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0 0.00000098352
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0057 0.0089 0.026
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0266 0.0668 0.1958
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0266 0.0668 0.2464
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0371 0.0958 0.1186
Trichomonas vaginalis PIKK family atypical protein kinase 0.008 0.0151 0.0546
Entamoeba histolytica Ran family GTPase 0.0026 0.0001 0.0009
Echinococcus granulosus voltage gated potassium channel 0.0025 0 0.00000098352
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0013 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0134 0.0301 0.0372
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0036 0.003 0.0037
Echinococcus multilocularis transient receptor potential cation channel 0.0025 0 0.00000098352
Schistosoma mansoni voltage-dependent calcium channel 0.0025 0 0.00000098352
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0051 0.0062
Echinococcus multilocularis chromobox protein 1 0.0089 0.0176 0.0217
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0134 0.0301 0.0372
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0067 0.0115 0.042
Schistosoma mansoni glutamate synthase 0.0266 0.0668 0.0827
Schistosoma mansoni sulfide quinone reductase 0.0266 0.0668 0.0827
Echinococcus multilocularis geminin 0.0722 0.1928 0.2387
Loa Loa (eye worm) programmed cell death 8 0.0266 0.0668 0.1959
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0013 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0134 0.0301 0.0372
Onchocerca volvulus 0.0134 0.0301 0.1095
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.0128 0.0128
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0067 0.0115 0.0309
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0266 0.0668 0.0667
Schistosoma mansoni hypothetical protein 0.0266 0.0668 0.0827
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0134 0.0301 0.0372
Echinococcus multilocularis two pore calcium channel protein 1 0.0025 0 0.00000098352
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0001 0.0001
Schistosoma mansoni biogenic amine receptor 0.0134 0.0301 0.0372
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0894 0.2404 0.7054
Schistosoma mansoni voltage-gated potassium channel 0.0036 0.003 0.0037
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0128 0.0285 0.0836
Brugia malayi hypothetical protein 0.0134 0.0301 0.0882
Echinococcus granulosus transient receptor potential gamma protein 0.0025 0 0.00000098352
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0063 0.0104 0.0128
Schistosoma mansoni transient receptor potential channel 0.0025 0 0.000001021
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0266 0.0668 0.1937
Echinococcus multilocularis voltage dependent calcium channel 0.0025 0 0.00000098352
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0266 0.0668 0.1958
Entamoeba histolytica hypothetical protein 0.0043 0.0051 0.0748
Schistosoma mansoni hypothetical protein 0.0722 0.1928 0.2387
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.001 0.0009
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0266 0.0668 0.2428
Schistosoma mansoni two-pore calcium channel 0.0025 0 0.00000098352
Schistosoma mansoni polycystin 1-related 0.013 0.029 0.0359
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0134 0.0301 0.0372
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0266 0.0668 0.1937
Loa Loa (eye worm) hypothetical protein 0.0056 0.0086 0.0252
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0737 0.1971 0.5783
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.1004 0.2708 0.7947
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0025 0 0.00000098352
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0025 0 0.00000098352
Trypanosoma brucei ATP-binding cassette protein, putative 0.0025 0.0001 0.0001
Brugia malayi hypothetical protein 0.0134 0.0301 0.0882
Echinococcus multilocularis neuropeptide receptor A26 0.0629 0.167 0.2067
Leishmania major protein kinase, putative 0.0066 0.0113 0.0113
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0112 0.0241 0.0241
Plasmodium falciparum LCCL domain-containing protein 0.013 0.029 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0095 0.034
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0067 0.0115 0.0309
Echinococcus granulosus 7tm_1 domain containing protein 0.0134 0.0301 0.0372
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.1004 0.2708 1
Echinococcus multilocularis BC026374 protein (S09 family) 0.0063 0.0104 0.0128
Echinococcus granulosus Ankyrin 0.0033 0.0021 0.0026
Loa Loa (eye worm) hypothetical protein 0.0134 0.0301 0.0882
Echinococcus multilocularis lipoxygenase domain containing protein 0.013 0.029 0.0359
Onchocerca volvulus Glucosylceramidase homolog 0.0375 0.0969 0.3529
Echinococcus multilocularis rhodopsin orphan GPCR 0.0134 0.0301 0.0372
Trichomonas vaginalis glucosylceramidase, putative 0.0375 0.0969 0.3528
Brugia malayi G protein-coupled receptor F59B2.13 0.0134 0.0301 0.0882
Loa Loa (eye worm) cytochrome P450 family protein 0.0085 0.0165 0.0483

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.7943 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.6169 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 6.5131 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 9.5283 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 11.5821 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 42.5615 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 100 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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