Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0103 | 0.0103 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.0012 | 0.0103 | 0.0103 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0012 | 0.0103 | 0.0375 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0035 | 0.0955 | 0.0955 |
Schistosoma mansoni | Smad4 | 0.0019 | 0.0383 | 0.0543 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0016 | 0.0282 | 0.0399 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.0521 |
Schistosoma mansoni | thyroid hormone receptor | 0.0035 | 0.0955 | 0.1354 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0055 | 0.1706 | 0.624 |
Schistosoma mansoni | transient receptor potential channel | 0.0076 | 0.2474 | 0.3507 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.1671 | 0.2368 |
Schistosoma mansoni | smad | 0.0019 | 0.0383 | 0.0543 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0103 | 0.0375 |
Schistosoma mansoni | nuclear receptor | 0.0016 | 0.0282 | 0.0399 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0016 | 0.0282 | 0.0399 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0116 | 0.3904 | 0.5534 |
Schistosoma mansoni | topbp1 | 0.0012 | 0.0103 | 0.0145 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0035 | 0.0955 | 0.1354 |
Brugia malayi | nuclear hormone receptor | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0054 | 0.1671 | 0.1671 |
Loa Loa (eye worm) | inositol-1 | 0.0084 | 0.2734 | 0.2734 |
Brugia malayi | hypothetical protein | 0.0082 | 0.2676 | 0.2676 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.2676 | 0.9789 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.0012 | 0.0103 | 0.0145 |
Brugia malayi | Smad1 | 0.0019 | 0.0383 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.3981 | 0.3981 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0019 | 0.0368 | 0.1523 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0055 | 0.1706 | 0.624 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0035 | 0.0955 | 0.0955 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0172 | 0.5971 | 0.5971 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0354 | 0.0354 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0016 | 0.0282 | 0.0399 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0368 | 0.1344 |
Echinococcus granulosus | nibrin | 0.0012 | 0.0103 | 0.0145 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0035 | 0.0955 | 0.1354 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0051 | 0.1535 | 1 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0055 | 0.1706 | 0.624 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0955 | 0.0955 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0035 | 0.0955 | 0.1354 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0076 | 0.2474 | 0.3507 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0035 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | DR-78 | 0.0016 | 0.0282 | 0.0282 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.2676 | 0.9789 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.0521 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0084 | 0.2734 | 1 |
Echinococcus granulosus | Smad4 | 0.0019 | 0.0383 | 0.0543 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0035 | 0.0955 | 0.1354 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.0521 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.0012 | 0.0103 | 0.0375 |
Brugia malayi | nuclear hormone receptor | 0.0035 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Schistosoma mansoni | hypothetical protein | 0.0118 | 0.3981 | 0.5643 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0035 | 0.0955 | 0.0955 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.1344 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0035 | 0.0955 | 0.1354 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0035 | 0.0955 | 0.1354 |
Brugia malayi | Isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.0368 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0051 | 0.1535 | 0.5615 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0035 | 0.0955 | 0.0955 |
Chlamydia trachomatis | DNA ligase | 0.0012 | 0.0103 | 1 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0112 | 0.3763 | 0.5335 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0055 | 0.1706 | 0.624 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0051 | 0.1535 | 0.2176 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | DKFZp564C0469 protein | 0.0012 | 0.0103 | 0.0103 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.0368 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0354 | 0.0354 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0019 | 0.0368 | 0.2074 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0055 | 0.1706 | 0.2418 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0016 | 0.0282 | 0.0282 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.2676 | 0.9789 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0075 | 0.2414 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0072 | 0.2322 | 0.3292 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0035 | 0.0955 | 0.1354 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0035 | 0.0955 | 0.0955 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0035 | 0.0955 | 0.1354 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0072 | 0.2322 | 0.8495 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0282 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0035 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0354 | 0.0354 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0084 | 0.2734 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0084 | 0.2734 | 0.3875 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0035 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0054 | 0.1671 | 0.1671 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0035 | 0.0955 | 0.0955 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0019 | 0.0368 | 0.1344 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0035 | 0.0955 | 0.1354 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0103 | 0.0375 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0051 | 0.1535 | 0.5615 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0018 | 0.0354 | 0.0501 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0055 | 0.1706 | 0.2418 |
Brugia malayi | MH1 domain containing protein | 0.0019 | 0.0383 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | Inositol-1 | 0.0084 | 0.2734 | 0.2734 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0016 | 0.0282 | 0.0399 |
Brugia malayi | tailless protein | 0.0016 | 0.0282 | 0.0282 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0082 | 0.2676 | 0.3793 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.0012 | 0.0103 | 0.0425 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0082 | 0.2676 | 0.3793 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0035 | 0.0955 | 0.0955 |
Brugia malayi | isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0354 | 0.0354 |
Brugia malayi | Transient-receptor-potential like protein | 0.0043 | 0.1251 | 0.1251 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0051 | 0.1535 | 0.5615 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0035 | 0.0955 | 0.0955 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0084 | 0.2734 | 1 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0076 | 0.2474 | 0.3507 |
Brugia malayi | hypothetical protein | 0.0146 | 0.5012 | 0.5012 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0035 | 0.0955 | 0.0955 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0055 | 0.1706 | 0.624 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.2676 | 0.3793 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0072 | 0.2322 | 0.8495 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0035 | 0.0955 | 0.1354 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.0521 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0955 | 0.0955 |
Schistosoma mansoni | coup transcription factor | 0.0035 | 0.0955 | 0.1354 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0103 | 0.0375 |
Schistosoma mansoni | transient receptor potential channel | 0.0116 | 0.3904 | 0.5534 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0035 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0955 | 0.0955 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0055 | 0.1706 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0035 | 0.0955 | 0.0955 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0019 | 0.0368 | 0.0521 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0016 | 0.0282 | 0.0399 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0019 | 0.0383 | 0.0543 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0035 | 0.0955 | 0.1906 |
Schistosoma mansoni | nuclear hormone receptor | 0.0035 | 0.0955 | 0.1354 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0084 | 0.2734 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0055 | 0.1706 | 0.624 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0016 | 0.0282 | 0.0399 |
Treponema pallidum | DNA ligase (lig) | 0.0012 | 0.0103 | 0.5 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0016 | 0.0282 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.111 | 0.111 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.1671 | 0.2368 |
Echinococcus granulosus | FTZ F1 alpha | 0.0035 | 0.0955 | 0.1354 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0276 | 0.976 | 0.976 |
Schistosoma mansoni | hypothetical protein | 0.0202 | 0.7054 | 1 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.0521 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0012 | 0.0103 | 0.0375 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0103 | 0.0375 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.0012 | 0.0103 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0955 | 0.0955 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0035 | 0.0955 | 0.1354 |
Onchocerca volvulus | 0.0016 | 0.0282 | 0.0562 | |
Brugia malayi | nuclear receptor RXR | 0.0016 | 0.0282 | 0.0282 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0072 | 0.2322 | 0.3292 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0019 | 0.0383 | 0.0543 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0019 | 0.0368 | 0.185 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0354 | 0.0354 |
Schistosoma mansoni | transient receptor potential channel | 0.0076 | 0.2474 | 0.3507 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0103 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0103 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.5012 | 0.5012 |
Onchocerca volvulus | 0.0016 | 0.0282 | 0.0562 | |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0035 | 0.0955 | 0.1354 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0016 | 0.0282 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0955 | 0.0955 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0076 | 0.2474 | 0.3507 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1671 | 0.1671 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0354 | 0.0501 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0047 | 0.138 | 0.8092 |
Schistosoma mansoni | nuclear hormone receptor | 0.0016 | 0.0282 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1251 | 0.1251 |
Schistosoma mansoni | smad1 5 8 and | 0.0019 | 0.0383 | 0.0543 |
Brugia malayi | MH1 domain containing protein | 0.0011 | 0.0069 | 0.0069 |
Onchocerca volvulus | 0.0012 | 0.0103 | 0.0205 | |
Echinococcus granulosus | replication factor c subunit 1 | 0.0012 | 0.0103 | 0.0145 |
Brugia malayi | ecdysteroid receptor | 0.0035 | 0.0955 | 0.0955 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.0521 |
Loa Loa (eye worm) | Smad1 | 0.0019 | 0.0383 | 0.0383 |
Schistosoma mansoni | nuclear hormone receptor | 0.0016 | 0.0282 | 0.0399 |
Schistosoma mansoni | smad1 5 8 and | 0.0019 | 0.0383 | 0.0543 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0035 | 0.0955 | 0.1354 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0019 | 0.0368 | 0.1344 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0055 | 0.1706 | 0.624 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0075 | 0.2414 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0011 | 0.0069 | 0.0069 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0016 | 0.0282 | 0.0399 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.1671 | 0.2368 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0035 | 0.0955 | 0.1354 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.0012 | 0.0103 | 0.0375 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0035 | 0.0955 | 0.1354 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0282 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0035 | 0.0955 | 0.1354 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0368 | 0.1344 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0084 | 0.2734 | 0.3875 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0035 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0055 | 0.1706 | 0.1706 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0012 | 0.0103 | 0.0375 |
Schistosoma mansoni | thyroid hormone receptor | 0.0035 | 0.0955 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0069 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0072 | 0.2322 | 0.8495 |
Echinococcus multilocularis | GPCR, family 2 | 0.0054 | 0.1671 | 0.2368 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0016 | 0.0282 | 0.0562 |
Schistosoma mansoni | inositol monophosphatase | 0.0084 | 0.2734 | 0.3875 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.0012 | 0.0103 | 0.0145 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0084 | 0.2734 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0103 | 0.0375 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0012 | 0.0103 | 0.0375 |
Loa Loa (eye worm) | nuclear factor I | 0.0011 | 0.0069 | 0.0069 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0047 | 0.138 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0354 | 0.0354 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0035 | 0.0955 | 0.0955 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0035 | 0.0955 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | nuclear receptor NHR-67 | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | topoisomerase | 0.0012 | 0.0103 | 0.0103 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0112 | 0.3763 | 0.5335 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0035 | 0.0955 | 0.1354 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.0012 | 0.0103 | 0.0103 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0035 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0035 | 0.0955 | 0.0955 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0043 | 0.1251 | 0.1773 |
Toxoplasma gondii | ATPase, AAA family protein | 0.0012 | 0.0103 | 0.0375 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0016 | 0.0282 | 0.0399 |
Schistosoma mansoni | smad1 5 8 and | 0.0019 | 0.0383 | 0.0543 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0016 | 0.0282 | 0.0399 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0084 | 0.2734 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0035 | 0.0955 | 0.0955 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0035 | 0.0955 | 0.1354 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0035 | 0.0955 | 0.0955 |
Echinococcus granulosus | geminin | 0.0202 | 0.7054 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0955 | 0.0955 |
Entamoeba histolytica | hypothetical protein | 0.0082 | 0.2676 | 0.9789 |
Brugia malayi | ecdysone receptor | 0.0016 | 0.0282 | 0.0282 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0016 | 0.0282 | 0.0399 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0035 | 0.0955 | 0.1354 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0035 | 0.0955 | 0.0955 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0054 | 0.1671 | 0.2368 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0103 | 0.0375 |
Brugia malayi | steroid hormone receptor | 0.0035 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0018 | 0.0354 | 0.0354 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0012 | 0.0103 | 0.0375 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0055 | 0.1706 | 0.2418 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0084 | 0.2734 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0016 | 0.0282 | 0.0399 |
Brugia malayi | MH2 domain containing protein | 0.0019 | 0.0383 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0354 | 0.0354 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0035 | 0.0955 | 0.1354 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0018 | 0.0354 | 0.0501 |
Echinococcus multilocularis | nibrin | 0.0012 | 0.0103 | 0.0145 |
Onchocerca volvulus | Huntingtin homolog | 0.0146 | 0.5012 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0035 | 0.0955 | 0.0955 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0168 | 0.5811 | 0.8237 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0055 | 0.1706 | 0.624 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0103 | 0.0103 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0016 | 0.0282 | 0.0399 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0035 | 0.0955 | 0.0955 |
Echinococcus granulosus | GPCR family 2 | 0.0054 | 0.1671 | 0.2368 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0016 | 0.0282 | 0.0282 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0054 | 0.1671 | 0.2368 |
Brugia malayi | conserved hypotetical protein | 0.0016 | 0.0282 | 0.0282 |
Schistosoma mansoni | zinc finger protein | 0.0016 | 0.0282 | 0.0399 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0055 | 0.1706 | 0.2418 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0054 | 0.1671 | 0.2368 |
Trypanosoma brucei | protein kinase, putative | 0.0055 | 0.1706 | 0.624 |
Schistosoma mansoni | hypothetical protein | 0.0202 | 0.7054 | 1 |
Giardia lamblia | Replication factor C, subunit 1 | 0.0012 | 0.0103 | 0.0601 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0047 | 0.138 | 0.5049 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.0012 | 0.0103 | 0.0375 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0082 | 0.2676 | 0.3793 |
Schistosoma mansoni | inositol monophosphatase | 0.0084 | 0.2734 | 0.3875 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0103 | 0.0103 |
Echinococcus multilocularis | Smad4 | 0.0019 | 0.0383 | 0.0543 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.2333 | 0.2333 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0043 | 0.1251 | 0.1773 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.5971 | 0.5971 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0016 | 0.0282 | 0.0282 |
Loa Loa (eye worm) | acetyltransferase | 0.0173 | 0.5988 | 0.5988 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0172 | 0.5971 | 0.5971 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0016 | 0.0282 | 0.0399 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0173 | 0.5988 | 0.5988 |
Brugia malayi | follicle stimulating hormone receptor | 0.0276 | 0.976 | 0.976 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0116 | 0.3904 | 0.5534 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.1706 | 0.2418 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0055 | 0.1706 | 0.624 |
Echinococcus multilocularis | smad | 0.0019 | 0.0383 | 0.0543 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0116 | 0.3904 | 0.5534 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0051 | 0.1535 | 0.5615 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0084 | 0.2734 | 1 |
Echinococcus granulosus | smad | 0.0019 | 0.0383 | 0.0543 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0055 | 0.1706 | 0.624 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0072 | 0.2322 | 0.3292 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0076 | 0.2474 | 0.3507 |
Schistosoma mansoni | nuclear receptor | 0.0016 | 0.0282 | 0.0399 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0035 | 0.0955 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0016 | 0.0282 | 0.0282 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0019 | 0.0383 | 0.0543 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0084 | 0.2734 | 1 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0103 | 0.0103 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0072 | 0.2322 | 0.8495 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0035 | 0.0955 | 0.1906 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0084 | 0.2734 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0035 | 0.0955 | 0.1906 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0018 | 0.0354 | 0.0501 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0019 | 0.0368 | 0.1344 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0368 | 0.1344 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0172 | 0.5971 | 0.5971 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0103 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0019 | 0.0383 | 0.0383 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0103 | 0.0103 |
Brugia malayi | nuclear receptor NHR-88 | 0.0016 | 0.0282 | 0.0282 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0054 | 0.1671 | 0.1671 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0072 | 0.2322 | 0.9622 |
Brugia malayi | MH1 domain containing protein | 0.0019 | 0.0383 | 0.0383 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0103 | 0.0103 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0035 | 0.0955 | 0.0955 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0035 | 0.0955 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.5012 | 0.5012 |
Brugia malayi | nuclear receptor RXR | 0.0018 | 0.0354 | 0.0354 |
Echinococcus multilocularis | geminin | 0.0202 | 0.7054 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0173 | 0.5988 | 0.8488 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0012 | 0.0103 | 0.0375 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0035 | 0.0955 | 0.1354 |
Schistosoma mansoni | topbp1 | 0.0012 | 0.0103 | 0.0145 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0019 | 0.0383 | 0.0383 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0055 | 0.1706 | 0.624 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0055 | 0.1706 | 0.624 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0054 | 0.1671 | 0.2368 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0072 | 0.2322 | 0.8495 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0354 | 0.0354 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0173 | 0.5988 | 0.8488 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0035 | 0.0955 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0955 | 0.0955 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0282 | 0.0282 |
Schistosoma mansoni | DNA ligase IV | 0.0012 | 0.0103 | 0.0145 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0019 | 0.0383 | 0.0543 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0354 | 0.0354 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0016 | 0.0282 | 0.0399 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0084 | 0.2734 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0146 | 0.5012 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0012 | 0.0103 | 0.0375 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0012 | 0.0103 | 0.0375 |
Brugia malayi | MH2 domain containing protein | 0.0019 | 0.0383 | 0.0383 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0072 | 0.2322 | 0.3292 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.3904 | 0.3904 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0118 | 0.3981 | 0.3981 |
Onchocerca volvulus | 0.0035 | 0.0955 | 0.1906 | |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0035 | 0.0955 | 0.1354 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0019 | 0.0383 | 0.0543 |
Brugia malayi | MAP kinase sur-1 | 0.0055 | 0.1706 | 0.1706 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.1671 | 0.2368 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0016 | 0.0282 | 0.0562 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0035 | 0.0955 | 0.0955 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 0.005 M | Tested for inhibitory activity against the recombinant HIV-1 protease | ChEMBL. | No reference |
IC50 (binding) | = 0.005 M | Tested for inhibitory activity against the recombinant HIV-1 protease | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.