Detailed information for compound 1422239

Basic information

Technical information
  • TDR Targets ID: 1422239
  • Name: methyl 2-[(6-methylpyridin-2-yl)methoxy]benzo ate
  • MW: 257.284 | Formula: C15H15NO3
  • H donors: 0 H acceptors: 2 LogP: 2.61 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccccc1OCc1cccc(n1)C
  • InChi: 1S/C15H15NO3/c1-11-6-5-7-12(16-11)10-19-14-9-4-3-8-13(14)15(17)18-2/h3-9H,10H2,1-2H3
  • InChiKey: CWXHRWMUABNWKO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • methyl 2-[(6-methyl-2-pyridyl)methoxy]benzoate
  • 2-[(6-methyl-2-pyridyl)methoxy]benzoic acid methyl ester
  • Oprea1_722024
  • STOCK1S-51921
  • ZINC00499947
  • MLS000079204
  • SMR000039323

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii ABC transporter family protein 0.0206 0.2193 0.2148
Brugia malayi MH2 domain containing protein 0.0385 0.5354 0.5354
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0647 1 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0206 0.2193 0.0278
Trypanosoma cruzi multidrug resistance protein E, putative 0.0206 0.2193 0.2998
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0206 0.2193 0.2148
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0647 1 1
Loa Loa (eye worm) hypothetical protein 0.0194 0.197 0.197
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0647 1 1
Loa Loa (eye worm) hypothetical protein 0.0178 0.1696 0.1696
Onchocerca volvulus 0.0647 1 0.5
Brugia malayi ABC transporter family protein 0.0206 0.2193 0.2193
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0206 0.2193 0.2148
Schistosoma mansoni tar DNA-binding protein 0.0582 0.884 0.884
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0647 1 1
Entamoeba histolytica P-glycoprotein-5 0.0647 1 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0647 1 1
Loa Loa (eye worm) hypothetical protein 0.0635 0.9777 0.9777
Plasmodium vivax ABC transporter B family member 4, putative 0.0206 0.2193 0.1857
Trichomonas vaginalis ABC transporter, putative 0.0647 1 1
Schistosoma mansoni multidrug resistance protein 0.0206 0.2193 0.2193
Loa Loa (eye worm) hypothetical protein 0.0206 0.2193 0.2193
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0206 0.2193 0.2998
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0647 1 1
Loa Loa (eye worm) RNA binding protein 0.0582 0.884 0.884
Brugia malayi Calcitonin receptor-like protein seb-1 0.0261 0.3157 0.3157
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0175 0.0175
Giardia lamblia ABC transporter 0.0476 0.6958 1
Echinococcus granulosus multidrug resistance associated protein 7 0.0206 0.2193 0.2193
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0647 1 1
Echinococcus granulosus ATP binding cassette sub family G 0.0488 0.7181 0.7181
Entamoeba histolytica ATP-binding cassette protein, putative 0.0206 0.2193 0.0278
Brugia malayi hypothetical protein 0.0206 0.2193 0.2193
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0647 1 1
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0206 0.2193 0.2148
Loa Loa (eye worm) hypothetical protein 0.0647 1 1
Entamoeba histolytica P-glycoprotein 6, putative 0.0206 0.2193 0.0278
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0647 1 1
Trichomonas vaginalis abcb9, putative 0.0647 1 1
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0647 1 1
Echinococcus multilocularis ATP binding cassette sub family G 0.0488 0.7181 0.7181
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0582 0.884 0.884
Loa Loa (eye worm) hypothetical protein 0.0106 0.0413 0.0413
Brugia malayi ABC transporter transmembrane region family protein 0.0206 0.2193 0.2193
Plasmodium vivax ABC transporter B family member 5, putative 0.0206 0.2193 0.1857
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0647 1 0.5
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0206 0.2193 0.2148
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0488 0.7181 0.7165
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0647 1 1
Plasmodium vivax ABC transporter B family member 7, putative 0.0206 0.2193 0.1857
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0647 1 1
Loa Loa (eye worm) hypothetical protein 0.0647 1 1
Loa Loa (eye worm) hypothetical protein 0.0206 0.2193 0.2193
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0206 0.2193 0.2148
Giardia lamblia Multidrug resistance-associated protein 1 0.0206 0.2193 0.0448
Entamoeba histolytica ABC transporter, putative 0.0206 0.2193 0.0278
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0175 0.0175
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0647 1 1
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0488 0.7181 0.7165
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0206 0.2193 0.2998
Schistosoma mansoni ABC transporter 0.0415 0.5887 0.5887
Brugia malayi multidrug resistance related protein 1 0.0206 0.2193 0.2193
Leishmania major p-glycoprotein e 0.0206 0.2193 0.2148
Giardia lamblia ABC transporter, putative 0.0206 0.2193 0.0448
Schistosoma mansoni tar DNA-binding protein 0.0582 0.884 0.884
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0206 0.2193 0.5
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0488 0.7181 0.7165
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0261 0.3157 0.3157
Plasmodium falciparum multidrug resistance-associated protein 1 0.0206 0.2193 0.1857
Plasmodium vivax multidrug resistance protein 2, putative 0.0206 0.2193 0.1857
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0488 0.7181 1
Schistosoma mansoni multidrug resistance protein 0.0206 0.2193 0.2193
Trichomonas vaginalis abcb9, putative 0.0647 1 1
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0647 1 1
Plasmodium falciparum ABC transporter B family member 7, putative 0.0206 0.2193 0.1857
Brugia malayi ABC transporter transmembrane region family protein 0.0206 0.2193 0.2193
Trypanosoma cruzi ABC transporter, putative 0.0488 0.7181 1
Echinococcus granulosus tar DNA binding protein 0.0582 0.884 0.884
Trypanosoma brucei ABC transporter, putative 0.0488 0.7181 1
Entamoeba histolytica P-glycoprotein-1 0.0647 1 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0206 0.2193 0.2148
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0647 1 1
Entamoeba histolytica multidrug resistance protein, putative 0.0206 0.2193 0.0278
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0175 0.0175
Giardia lamblia Multidrug resistance-associated protein 1 0.0206 0.2193 0.0448
Brugia malayi RNA recognition motif domain containing protein 0.0582 0.884 0.884
Trichomonas vaginalis ABC transporter, putative 0.0647 1 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0206 0.2193 0.2148
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0647 1 1
Trichomonas vaginalis ABC transporter, putative 0.0647 1 1
Trypanosoma brucei PAB1-binding protein , putative 0.0106 0.0413 0.05
Echinococcus granulosus ATP binding cassette sub family G 0.0488 0.7181 0.7181
Echinococcus multilocularis ATP binding cassette sub family G 0.0488 0.7181 0.7181
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0175 0.0175
Schistosoma mansoni multidrug resistance protein 0.0647 1 1
Loa Loa (eye worm) hypothetical protein 0.0194 0.197 0.197
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0647 1 1
Entamoeba histolytica ABC transporter, putative 0.0488 0.7181 0.649
Loa Loa (eye worm) TAR-binding protein 0.0582 0.884 0.884
Schistosoma mansoni tar DNA-binding protein 0.0582 0.884 0.884
Echinococcus multilocularis multidrug resistance protein 1 0.0647 1 1
Schistosoma mansoni multidrug resistance protein 0.0194 0.197 0.197
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0647 1 1
Giardia lamblia MRP-like ABC transporter 0.0206 0.2193 0.0448
Plasmodium falciparum ABC transporter B family member 3, putative 0.0206 0.2193 0.1857
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0206 0.2193 0.2148
Echinococcus granulosus ATP binding cassette sub family B 0.0206 0.2193 0.2193
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0647 1 1
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0488 0.7181 1
Plasmodium vivax multidrug resistance protein 1, putative 0.0647 1 1
Loa Loa (eye worm) ABC transporter 0.0206 0.2193 0.2193
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0206 0.2193 0.2998
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0206 0.2193 0.5
Echinococcus granulosus multidrug resistance protein 1 0.0647 1 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0647 1 1
Echinococcus multilocularis multidrug resistance associated protein 1 0.0206 0.2193 0.2193
Echinococcus multilocularis ATP binding cassette sub family B 0.0206 0.2193 0.2193
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0261 0.3157 0.3157
Loa Loa (eye worm) ABC transporter 0.0206 0.2193 0.2193
Entamoeba histolytica P-glyco protein 6, putative 0.0647 1 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0206 0.2193 0.2193
Brugia malayi TAR-binding protein 0.0582 0.884 0.884
Leishmania major p-glycoprotein 0.0647 1 1
Brugia malayi RNA binding protein 0.0582 0.884 0.884
Echinococcus multilocularis tar DNA binding protein 0.0582 0.884 0.884
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0206 0.2193 0.2148
Trichomonas vaginalis ABC transporter, putative 0.0647 1 1
Trichomonas vaginalis abcb9, putative 0.0647 1 1
Entamoeba histolytica P-glycoprotein-2, putative 0.0647 1 1
Schistosoma mansoni smdr1 0.0206 0.2193 0.2193
Brugia malayi P-glycoprotein-like protein 0.0206 0.2193 0.2193
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0206 0.2193 0.2998
Schistosoma mansoni multidrug resistance protein 0.0647 1 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0647 1 1
Schistosoma mansoni smdr2 0.0647 1 1
Plasmodium vivax ABC transporter B family member 6, putative 0.0206 0.2193 0.1857
Echinococcus granulosus multidrug resistance protein 1 0.0454 0.6569 0.6569
Toxoplasma gondii LsmAD domain-containing protein 0.0106 0.0413 0.0358
Echinococcus granulosus multidrug resistance associated protein 1 0.0206 0.2193 0.2193
Plasmodium falciparum multidrug resistance protein 2 0.0206 0.2193 0.1857
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0206 0.2193 0.2998
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0647 1 1
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0206 0.2193 0.2148
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0175 0.0175
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0647 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0647 1 1
Plasmodium falciparum multidrug resistance-associated protein 2 0.0206 0.2193 0.1857
Echinococcus multilocularis 0.0206 0.2193 0.2193
Trypanosoma brucei ATP-binding cassette protein, putative 0.0488 0.7181 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0488 0.7181 1
Plasmodium falciparum multidrug resistance protein 1 0.0647 1 1
Brugia malayi ABC transporter family protein 0.0206 0.2193 0.2193
Plasmodium falciparum ABC transporter B family member 5, putative 0.0206 0.2193 0.1857
Brugia malayi ABC transporter family protein 0.0647 1 1
Plasmodium falciparum ABC transporter B family member 6, putative 0.0206 0.2193 0.1857
Leishmania major pentamidine resistance protein 1 0.0206 0.2193 0.2148
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0206 0.2193 0.2998
Trichomonas vaginalis taga, putative 0.0647 1 1
Plasmodium falciparum ABC transporter G family member 2 0.0488 0.7181 0.706
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0647 1 1
Schistosoma mansoni tar DNA-binding protein 0.0582 0.884 0.884
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0194 0.197 0.197
Loa Loa (eye worm) ABC transporter 0.0206 0.2193 0.2193
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0206 0.2193 0.1857
Schistosoma mansoni multidrug resistance protein 0.0647 1 1
Toxoplasma gondii ABC transporter, putative 0.0206 0.2193 0.2148
Entamoeba histolytica P-glycoprotein-2 0.0647 1 1
Entamoeba histolytica hypothetical protein 0.0206 0.2193 0.0278
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0206 0.2193 0.2193
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0647 1 1
Trypanosoma brucei p-glycoprotein 0.0206 0.2193 0.2998
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0488 0.7181 0.7181
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0206 0.2193 0.5
Leishmania major hypothetical protein, conserved 0.0106 0.0413 0.0358
Schistosoma mansoni tar DNA-binding protein 0.0582 0.884 0.884
Echinococcus granulosus ATP binding cassette sub family B 0.0206 0.2193 0.2193
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0647 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0647 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0647 1 1
Brugia malayi ABC transporter 0.0206 0.2193 0.2193
Brugia malayi ABC transporter transmembrane region family protein 0.0194 0.197 0.197
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0206 0.2193 0.2193
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0647 1 1
Echinococcus granulosus multidrug resistance protein 1 0.0647 1 1
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0206 0.2193 0.5
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0206 0.2193 0.2148
Schistosoma mansoni multidrug resistance protein 0.0206 0.2193 0.2193
Entamoeba histolytica ATP-binding cassette protein, putative 0.0206 0.2193 0.0278
Brugia malayi ABC transporter family protein 0.0206 0.2193 0.2193
Echinococcus multilocularis ATP binding cassette sub family G 0.0488 0.7181 0.7181
Echinococcus granulosus ATP binding cassette sub family G 0.0488 0.7181 0.7181
Loa Loa (eye worm) ABC transporter 0.0415 0.5887 0.5887
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.0413 0.05
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0206 0.2193 0.2148
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0206 0.2193 0.1857
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0647 1 1
Brugia malayi ABC transporter 0.0194 0.197 0.197
Loa Loa (eye worm) hypothetical protein 0.0261 0.3157 0.3157
Echinococcus granulosus multidrug resistance protein 1 0.0454 0.6569 0.6569
Entamoeba histolytica ATP-binding cassette protein, putative 0.0206 0.2193 0.0278
Echinococcus granulosus multidrug resistance protein 1 0.0647 1 1
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0206 0.2193 0.2998
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0206 0.2193 0.2998
Entamoeba histolytica P-glycoprotein-2 0.0647 1 1
Schistosoma mansoni hypothetical protein 0.0178 0.1696 0.1696
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0647 1 1
Entamoeba histolytica P-glycoprotein 5, putative 0.0647 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0175 0.0175
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0175 0.0175
Loa Loa (eye worm) MH2 domain-containing protein 0.0385 0.5354 0.5354
Entamoeba histolytica P-glycoprotein 6, putative 0.0206 0.2193 0.0278
Schistosoma mansoni multidrug resistance protein 0.0206 0.2193 0.2193
Loa Loa (eye worm) multidrug resistance protein 3 0.0647 1 1
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0206 0.2193 0.2193
Brugia malayi ABC transporter family protein 0.0415 0.5887 0.5887
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0175 0.0175
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0454 0.6569 0.5728
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0647 1 1
Brugia malayi latrophilin 2 splice variant baaae 0.0178 0.1696 0.1696
Leishmania major ABC-thiol transporter 0.0206 0.2193 0.2148
Loa Loa (eye worm) hypothetical protein 0.0206 0.2193 0.2193
Loa Loa (eye worm) transcription factor SMAD2 0.0385 0.5354 0.5354
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0647 1 1
Plasmodium falciparum ABC transporter B family member 4, putative 0.0206 0.2193 0.1857
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0402 0.5663 0.4445
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0488 0.7181 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.0413 0.05
Trypanosoma brucei multidrug resistance protein E 0.0206 0.2193 0.2998
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0206 0.2193 0.2148
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0647 1 1
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0635 0.9777 0.9777
Echinococcus granulosus ATP binding cassette sub family B 0.0194 0.197 0.197
Plasmodium vivax ABC transporter G family member 2, putative 0.0488 0.7181 0.706
Plasmodium vivax ABC transporter B family member 3, putative 0.0206 0.2193 0.1857
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0647 1 1
Echinococcus multilocularis multidrug resistance protein 1 0.0647 1 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0635 0.9777 0.9777
Echinococcus multilocularis multidrug resistance associated protein 7 0.0206 0.2193 0.2193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0175 0.0175
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0206 0.2193 0.0278
Echinococcus multilocularis ATP binding cassette sub family B 0.0206 0.2193 0.2193
Schistosoma mansoni multidrug resistance protein 0.0206 0.2193 0.2193
Schistosoma mansoni hypothetical protein 0.0402 0.5663 0.5663
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0206 0.2193 0.2148
Echinococcus multilocularis ATP binding cassette sub family B 0.0206 0.2193 0.2193
Echinococcus multilocularis multidrug resistance protein 1 0.0454 0.6569 0.6569
Brugia malayi hypothetical protein 0.0106 0.0413 0.0413

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) = 112.2018 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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