Detailed information for compound 1431832

Basic information

Technical information
  • TDR Targets ID: 1431832
  • Name: ethyl 4-[7-(difluoromethyl)-5-(4-methylphenyl )pyrazolo[1,5-a]pyrimidine-3-carbonyl]piperaz ine-1-carboxylate
  • MW: 443.447 | Formula: C22H23F2N5O3
  • H donors: 0 H acceptors: 4 LogP: 2.51 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)N1CCN(CC1)C(=O)c1cnn2c1nc(cc2C(F)F)c1ccc(cc1)C
  • InChi: 1S/C22H23F2N5O3/c1-3-32-22(31)28-10-8-27(9-11-28)21(30)16-13-25-29-18(19(23)24)12-17(26-20(16)29)15-6-4-14(2)5-7-15/h4-7,12-13,19H,3,8-11H2,1-2H3
  • InChiKey: IOPXJXXRMQVDNU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-[[7-(difluoromethyl)-5-(4-methylphenyl)-3-pyrazolo[1,5-a]pyrimidinyl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester
  • 4-[7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazine-1-carboxylic acid ethyl ester
  • ethyl 4-[7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonylpiperazine-1-carboxylate
  • ethyl 4-{[7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}-1-piperazinecarboxylate
  • MLS000052800
  • SMR000082634
  • STK339868

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ubiquitin specific peptidase 2 Starlite/ChEMBL No references
Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens thyroid stimulating hormone receptor Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Echinococcus granulosus ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania infantum ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania mexicana 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania donovani 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum expressed protein Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium hominis scully CG7113-PA Get druggable targets OG5_129031 All targets in OG5_129031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania braziliensis 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania infantum 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania braziliensis ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum IPR015063,Domain of unknown function DUF1873,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium parvum ubiquitin C-terminal hydrolase of the cysteine proteinase fold Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans ubiquitin-specific protease Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum ko:K00022 3-hydroxyacyl-CoA dehydrogenase [EC1.1.1.35], putative Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium hominis ubiquitin specific protease 66 Get druggable targets OG5_127431 All targets in OG5_127431
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania donovani ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) follicle stimulating hormone receptor Get druggable targets OG5_130089 All targets in OG5_130089
Echinococcus multilocularis ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma brucei gambiense ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum ko:K01072 ubiquitin thiolesterase [EC3.1.2.15], putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania mexicana ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium parvum scully CG7113-PA, putative Get druggable targets OG5_129031 All targets in OG5_129031
Trypanosoma congolense ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum IPR001394,Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase hydroxysteroid (17-beta) dehydrogenase 10 252 aa 251 aa 24.7 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Plasmodium falciparum ubiquitin specific protease, putative ubiquitin specific peptidase 2 362 aa 378 aa 25.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis ribose-phosphate pyrophosphokinase, putative 0.0331 0.2091 0.2091
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.018 0.018
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.1413 1 1
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.1413 1 1
Mycobacterium leprae Probable hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (IMP pho 0.1083 0.7582 1
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0331 0.2091 0.2091
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.1413 1 1
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0331 0.2091 0.2091
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0331 0.2091 0.2091
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.1413 1 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.028 0.1717 0.821
Mycobacterium tuberculosis Adenine phosphoribosyltransferase Apt (APRT) (AMP diphosphorylase) (AMP pyrophosphorylase) (transphosphoribosidase) 0.0331 0.2091 0.2582
Leishmania major orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative 0.0331 0.2091 0.2091
Echinococcus granulosus adenine phosphoribosyltransferase 0.0331 0.2091 0.2091
Trichomonas vaginalis hypoxanthine-guanine phosphoribosyltransferase, putative 0.1413 1 1
Plasmodium falciparum hypoxanthine-guanine phosphoribosyltransferase 0.1413 1 1
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.1413 1 1
Mycobacterium tuberculosis Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (imp pyrophosphor 0.1083 0.7582 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0979 0.6828 0.6828
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.018 0.018
Mycobacterium tuberculosis Conserved protein 0.0331 0.2091 0.2582
Brugia malayi orotate phosphoribosyltransferase family protein 0.0331 0.2091 0.2091
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.1413 1 1
Mycobacterium tuberculosis Conserved protein 0.0331 0.2091 0.2582
Treponema pallidum hypothetical protein 0.0331 0.2091 0.5
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.1413 1 1
Mycobacterium ulcerans hypothetical protein 0.0331 0.2091 0.1947
Brugia malayi follicle stimulating hormone receptor 0.028 0.1717 0.1717
Treponema pallidum phosphoribosylpyrophosphate synthetase 0.0331 0.2091 0.5
Mycobacterium ulcerans hypoxanthine-guanine phosphoribosyltransferase Hpt 0.1413 1 1
Mycobacterium ulcerans bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 0.0331 0.2091 0.1947
Mycobacterium ulcerans orotate phosphoribosyltransferase 0.0331 0.2091 0.1947
Wolbachia endosymbiont of Brugia malayi orotate phosphoribosyltransferase 0.0331 0.2091 0.5
Echinococcus granulosus uridine 5' monophosphate synthase 0.0331 0.2091 0.2091
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase, putative 0.1413 1 1
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0331 0.2091 0.2091
Mycobacterium tuberculosis Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.0331 0.2091 0.2582
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.018 0.018
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0331 0.2091 0.2091
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.1413 1 1
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0331 0.2091 0.2091
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.1413 1 1
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0331 0.2091 0.2091
Trypanosoma brucei orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0331 0.2091 0.2091
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0146 0.0697
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0331 0.2091 0.2091
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.1413 1 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0 0.5
Brugia malayi Adenine phosphoribosyltransferase 0.0331 0.2091 0.2091
Treponema pallidum adenine phosphoribosyltransferase 0.0331 0.2091 0.5
Wolbachia endosymbiont of Brugia malayi amidophosphoribosyltransferase 0.0331 0.2091 0.5
Leishmania major xanthine phosphoribosyltransferase 0.1413 1 1
Echinococcus multilocularis adenine phosphoribosyltransferase 0.0331 0.2091 0.2091
Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl transferase HXGPRT 0.1413 1 1
Mycobacterium tuberculosis Probable pyrimidine operon regulatory protein PyrR 0.0331 0.2091 0.2582
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0331 0.2091 0.2091
Mycobacterium ulcerans amidophosphoribosyltransferase 0.0331 0.2091 0.1947
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0331 0.2091 0.2091
Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase, putative 0.1413 1 1
Mycobacterium tuberculosis Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) 0.0331 0.2091 0.2582
Schistosoma mansoni uracil phosphoribosyltransferase 0.0331 0.2091 0.2091
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.1413 1 1
Onchocerca volvulus 0.1413 1 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.018 0.018
Loa Loa (eye worm) orotate phosphoribosyltransferase 0.0331 0.2091 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0331 0.2091 0.2582
Mycobacterium ulcerans adenine phosphoribosyltransferase 0.0331 0.2091 0.1947
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.1413 1 1
Loa Loa (eye worm) adenine phosphoribosyltransferase 0.0331 0.2091 1
Echinococcus multilocularis uridine 5' monophosphate synthase 0.0331 0.2091 0.2091
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0331 0.2091 0.2091
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.018 0.018
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0331 0.2091 0.2091
Schistosoma mansoni orotidine 5'-phosphate decarboxylase 0.0331 0.2091 0.2091
Giardia lamblia Adenine phosphoribosyltransferase 0.0331 0.2091 0.2091
Giardia lamblia Guanine phosphoribosyltransferase 0.1413 1 1
Leishmania major adenine phosphoribosyltransferase 0.0331 0.2091 0.2091
Trichomonas vaginalis Ribose-phosphate pyrophosphokinase, putative 0.0331 0.2091 0.2091
Leishmania major hypoxanthine-guanine phosphoribosyltransferase 0.1413 1 1

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.3162 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.3162 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.5785 uM PubChem BioAssay. qHTS screen for small molecules that inhibit ELG1-dependent DNA repair: Hit Confirmation with 5FU Viability. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.5338 uM PubChem BioAssay. HTS assay for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1: Hit Confirmation. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.6626 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.785 uM PubChem BioAssay. qHTS screen for small molecules that inhibit ELG1-dependent DNA repair: Hit Confirmation with Unstimulated Viability Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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