Detailed information for compound 1445191

Basic information

Technical information
  • TDR Targets ID: 1445191
  • Name: [2-(furan-2-ylmethylamino)-2-oxoethyl] 1-benz ofuran-2-carboxylate
  • MW: 299.278 | Formula: C16H13NO5
  • H donors: 1 H acceptors: 2 LogP: 2.45 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(COC(=O)c1cc2c(o1)cccc2)NCc1ccco1
  • InChi: 1S/C16H13NO5/c18-15(17-9-12-5-3-7-20-12)10-21-16(19)14-8-11-4-1-2-6-13(11)22-14/h1-8H,9-10H2,(H,17,18)
  • InChiKey: DIJHPQUBITVKDW-UHFFFAOYSA-N  

Network

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Synonyms

  • [2-(2-furylmethylamino)-2-oxo-ethyl] benzofuran-2-carboxylate
  • 2-benzofurancarboxylic acid [2-(2-furylmethylamino)-2-oxoethyl] ester
  • benzofuran-2-carboxylic acid [2-(2-furylmethylamino)-2-keto-ethyl] ester
  • [2-(furan-2-ylmethylamino)-2-oxo-ethyl] 1-benzofuran-2-carboxylate
  • ZINC04332493
  • T5553573

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.4751 0.4751
Echinococcus multilocularis g-protein coupled receptor 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Brugia malayi Dopamine receptor protein 2 0.0024 0.4751 0.5295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.4751 0.4751
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni biogenic amine receptor 0.0024 0.4751 0.4751
Schistosoma mansoni neuropeptide receptor 0.0024 0.4751 0.4751
Onchocerca volvulus 0.0024 0.4751 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus sex peptide receptor 0.0024 0.4751 0.5295
Schistosoma mansoni biogenic amine receptor 0.0024 0.4751 0.4751
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.1028 0.1145
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0024 0.4751 0.4751
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni hypothetical protein 0.0024 0.4751 0.4751
Brugia malayi follicle stimulating hormone receptor 0.0024 0.4751 0.5295
Schistosoma mansoni neuropeptide receptor 0.0024 0.4751 0.4751
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.4751 0.4751
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.1028 0.1145
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.8972 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Schistosoma mansoni amine GPCR 0.0024 0.4751 0.4751
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Echinococcus granulosus g-protein coupled receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.4751 0.5295
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0024 0.4751 0.5295
Echinococcus multilocularis neuropeptide receptor 0.0024 0.4751 0.5295
Brugia malayi Cytochrome P450 family protein 0.0028 0.5719 0.6374
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Schistosoma mansoni opsin-like receptor 0.0024 0.4751 0.4751
Brugia malayi putative neuropeptide receptor NPR1 0.0024 0.4751 0.5295
Echinococcus granulosus alpha 1A adrenergic receptor 0.0024 0.4751 0.5295
Echinococcus granulosus neuropeptide receptor 0.0024 0.4751 0.5295
Schistosoma mansoni opsin-like receptor 0.0024 0.4751 0.4751
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.4751 0.4751
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0024 0.4751 0.5295
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0017 0.259 0.5
Schistosoma mansoni biogenic amine receptor 0.0024 0.4751 0.4751
Echinococcus granulosus serotonin receptor 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.259 0.2887
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.4751 0.4751
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.4751 0.5295
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.4751 0.5295
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0024 0.4751 0.5295
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0024 0.4751 0.5
Echinococcus multilocularis g protein coupled receptor 0.0024 0.4751 0.5295
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0024 0.4751 0.4751
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0024 0.4751 0.5295
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.4751 0.4751
Brugia malayi hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.259 0.2887
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.8236 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0024 0.4751 0.4751
Echinococcus multilocularis allatostatin A receptor 0.0024 0.4751 0.5295
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.4751 0.4751
Schistosoma mansoni voltage-gated potassium channel 0.0043 1 1
Brugia malayi hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.4751 0.4751
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.4751 0.5295
Brugia malayi ORL1-like opioid receptor 0.0024 0.4751 0.5295
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0024 0.4751 0.5295
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.4751 0.4751
Echinococcus granulosus orexin receptor type 2 0.0024 0.4751 0.5295
Echinococcus granulosus g protein coupled receptor 0.0024 0.4751 0.5295
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.1028 0.1028
Echinococcus multilocularis fmrfamide receptor 0.0024 0.4751 0.5295
Echinococcus multilocularis somatostatin receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus multilocularis G protein coupled receptor 139 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Brugia malayi Dopamine receptor protein 1 0.0024 0.4751 0.5295
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Onchocerca volvulus Neuropeptide F receptor homolog 0.0024 0.4751 0.5
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.4751 0.5295
Schistosoma mansoni amine GPCR 0.0024 0.4751 0.4751
Schistosoma mansoni alpha-1 adrenergic receptor 0.0024 0.4751 0.4751
Echinococcus multilocularis serotonin receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) TYRA-2 protein 0.0024 0.4751 0.5295
Brugia malayi AKH receptor 0.0024 0.4751 0.5295
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0024 0.4751 0.5295
Schistosoma mansoni hypothetical protein 0.0024 0.4751 0.4751
Brugia malayi hypothetical protein 0.0024 0.4751 0.5295
Brugia malayi G-protein coupled receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus tachykinin peptides receptor 99D 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Brugia malayi RE15519p 0.0024 0.4751 0.5295
Schistosoma mansoni neuropeptide f receptor 76f 0.0024 0.4751 0.4751
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.8972 1
Brugia malayi hypothetical protein 0.0024 0.4751 0.5295
Brugia malayi G-protein coupled receptor 0.0024 0.4751 0.5295
Brugia malayi neuropeptide F receptor 0.0024 0.4751 0.5295
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.4751 0.4751
Brugia malayi putative neuropeptide receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0011 0.1028 0.1145
Echinococcus multilocularis G-protein coupled receptor, putative 0.0024 0.4751 0.5295
Brugia malayi Cytochrome P450 family protein 0.0017 0.259 0.2887
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0024 0.4751 0.5295
Echinococcus multilocularis sex peptide receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus multilocularis neuropeptide s receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus multilocularis g protein coupled receptor 0.0024 0.4751 0.5295
Echinococcus granulosus g protein coupled receptor 0.0024 0.4751 0.5295
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0024 0.4751 0.5295
Echinococcus granulosus dro:myosuppressin receptor 0.0024 0.4751 0.5295
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0024 0.4751 0.5295
Trypanosoma brucei cytochrome P450, putative 0.0017 0.259 0.5
Schistosoma mansoni opsin-like receptor 0.0024 0.4751 0.4751
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0024 0.4751 0.4751
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.4751 0.4751
Onchocerca volvulus 0.0024 0.4751 0.5
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Loa Loa (eye worm) hypothetical protein 0.0009 0.0444 0.0495
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.4751 0.5295
Brugia malayi hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus peptide allatostatin:somatostatin 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.8236 1
Brugia malayi G protein-coupled receptor 0.0024 0.4751 0.5295
Echinococcus granulosus hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus G protein coupled receptor 139 0.0024 0.4751 0.5295
Brugia malayi larval opioid receptor 0.0024 0.4751 0.5295
Echinococcus granulosus g protein coupled receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni neuropeptide receptor 0.0024 0.4751 0.4751
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0024 0.4751 0.4751
Echinococcus multilocularis neuropeptide receptor A26 0.0024 0.4751 0.5295
Brugia malayi GnHR receptor homolog 0.0024 0.4751 0.5295
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0024 0.4751 0.5295
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Brugia malayi Melatonin receptor type 1A 0.0024 0.4751 0.5295
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0024 0.4751 0.5295
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.4751 0.5295
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.4751 0.5295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.4751 0.4751
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.1028 0.1028
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.4751 0.5295
Echinococcus multilocularis dro:myosuppressin receptor 0.0024 0.4751 0.5295
Echinococcus granulosus fmrfamide receptor 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.4751 0.5295
Echinococcus granulosus 7TM GPCR rhodopsin 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Brugia malayi hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.4751 0.4751
Brugia malayi G protein-coupled receptor F59B2.13 0.0024 0.4751 0.5295
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.1028 0.1145
Onchocerca volvulus 0.0024 0.4751 0.5
Loa Loa (eye worm) hypothetical protein 0.0034 0.7495 0.8354
Brugia malayi Serotonin receptor 0.0024 0.4751 0.5295
Schistosoma mansoni amine GPCR 0.0024 0.4751 0.4751
Brugia malayi hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) CYP4Cod1 0.0017 0.259 0.2887
Brugia malayi Cytochrome P450 family protein 0.0017 0.259 0.2887
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.5719 0.6374
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Echinococcus multilocularis neuropeptide FF receptor 2 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni amine GPCR 0.0024 0.4751 0.4751
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) melatonin receptor type 1A 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.4751 0.5295
Echinococcus multilocularis serotonin receptor 0.0024 0.4751 0.5295
Brugia malayi neuropeptide F receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0024 0.4751 0.5295
Leishmania major cytochrome p450-like protein 0.0017 0.259 0.5
Schistosoma mansoni histamine h1 receptor 0.0024 0.4751 0.4751
Brugia malayi Serotonin receptor 0.0024 0.4751 0.5295
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.4751 0.5295
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0024 0.4751 0.5295
Echinococcus granulosus somatostatin receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus multilocularis orexin receptor type 2 0.0024 0.4751 0.5295
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0024 0.4751 0.5295
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0024 0.4751 0.4751
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus 7tm_1 domain containing protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.8972 1
Onchocerca volvulus 0.0024 0.4751 0.5
Schistosoma mansoni hypothetical protein 0.0024 0.4751 0.4751
Echinococcus multilocularis neuropeptide receptor 0.0024 0.4751 0.5295
Echinococcus granulosus neuropeptide FF receptor 2 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus neuropeptide receptor 0.0024 0.4751 0.5295
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Echinococcus multilocularis fmrfamide receptor 0.0024 0.4751 0.5295
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.259 0.5
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0024 0.4751 0.5295
Schistosoma mansoni amine GPCR 0.0024 0.4751 0.4751
Echinococcus granulosus neuropeptide s receptor 0.0024 0.4751 0.5295
Brugia malayi hypothetical protein 0.0024 0.4751 0.5295
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0024 0.4751 0.5295
Schistosoma mansoni adenoreceptor 0.0024 0.4751 0.4751
Echinococcus multilocularis g protein coupled receptor 0.0024 0.4751 0.5295
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Brugia malayi Dopamine receptor 0.0024 0.4751 0.5295
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0024 0.4751 0.5295
Schistosoma mansoni growth hormone secretagogue receptor 0.0024 0.4751 0.4751
Echinococcus granulosus neuropeptide receptor A26 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Onchocerca volvulus 0.0024 0.4751 0.5
Echinococcus granulosus allatostatin A receptor 0.0024 0.4751 0.5295
Onchocerca volvulus 0.0024 0.4751 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0024 0.4751 0.4751
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.4751 0.4751
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus voltage gated potassium channel 0.0011 0.1028 0.1145
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni myosin xvIII 0.0024 0.4751 0.4751
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.1028 0.1145
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0024 0.4751 0.4751
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0024 0.4751 0.5295
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.4751 0.4751
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.8972 1
Brugia malayi hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni neuropeptide receptor 0.0024 0.4751 0.4751
Brugia malayi sulfakinin receptor protein 0.0024 0.4751 0.5295
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Brugia malayi hypothetical protein 0.0024 0.4751 0.5295
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.4751 0.4751
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.4751 0.4751
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.259 0.5
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.4751 0.5295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.4751 0.4751
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0024 0.4751 0.5295
Schistosoma mansoni hypothetical protein 0.0024 0.4751 0.4751
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.4751 0.5295
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.4751 0.5295
Brugia malayi Tachykinin-like peptides receptor 99D 0.0024 0.4751 0.5295
Loa Loa (eye worm) hypothetical protein 0.0024 0.4751 0.5295
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.4751 0.5295
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.4751 0.5295

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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