TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 426.464 | Formula: C26H22N2O4
H donors: 2 H acceptors: 3 LogP: 2.79 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: CC1=C(C(=O)Nc2ccccc2)C(C2=C(CCCC2=N1)O)c1coc2c(c1=O)cccc2
InChi: 1S/C26H22N2O4/c1-15-22(26(31)28-16-8-3-2-4-9-16)23(24-19(27-15)11-7-12-20(24)29)18-14-32-21-13-6-5-10-17(21)25(18)30/h2-6,8-10,13-14,23,29H,7,11-12H2,1H3,(H,28,31)
InChiKey: TVBGTDDCLKFNRG-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	nuclear factor, erythroid 2-like 2	Starlite/ChEMBL	No references
Homo sapiens	GNAS complex locus	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma japonicum	ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative	Get druggable targets OG5_131088	All targets in OG5_131088
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	Get druggable targets OG5_131088	All targets in OG5_131088
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	Get druggable targets OG5_131088	All targets in OG5_131088

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Schistosoma mansoni	GTP-binding protein alpha subunit gna	GNAS complex locus	394 aa	450 aa	28.7 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	contactin	0.0007	0.0061	0.0061
Schistosoma mansoni	titin	0.0007	0.0061	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0016	0.1367	0.1367
Onchocerca volvulus		0.0007	0.0061	0.0448
Loa Loa (eye worm)	pregnancy-associated plasma protein-E	0.0016	0.1367	0.1367
Brugia malayi	Cytochrome P450 family protein	0.0058	0.7201	0.7201
Echinococcus multilocularis	roundabout 2	0.0007	0.0061	0.0061
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0007	0.0061	0.0061
Brugia malayi	Cytochrome P450 family protein	0.0058	0.7201	0.7201
Echinococcus multilocularis		0.003	0.3271	0.3271
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.0061	0.0061
Onchocerca volvulus		0.0016	0.1367	1
Onchocerca volvulus		0.0016	0.1367	1
Mycobacterium tuberculosis	Probable cytochrome P450 124 Cyp124	0.003	0.3271	0.5
Schistosoma mansoni	ubiquitin-specific peptidase 2 (C19 family)	0.0078	1	1
Loa Loa (eye worm)	CYP4Cod1	0.0058	0.7201	0.7201
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.6786	0.6786
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0078	1	1
Onchocerca volvulus		0.0016	0.1367	1
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0043	0.515	0.515
Echinococcus multilocularis	roundabout 2	0.0007	0.0061	0.0061
Schistosoma mansoni	hemicentin	0.0007	0.0061	0.0061
Mycobacterium tuberculosis	Probable cytochrome P450 137 Cyp137	0.003	0.3271	0.5
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0007	0.0061	0.0061
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	0.0058	0.7201	1
Onchocerca volvulus		0.0016	0.1367	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.0061	0.0061
Mycobacterium tuberculosis	Probable cytochrome P450 136 Cyp136	0.003	0.3271	0.5
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.0061	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0028	0.3051	0.3051
Mycobacterium tuberculosis	Probable cytochrome P450 128 Cyp128	0.003	0.3271	0.5
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0007	0.0061	0.0061
Echinococcus multilocularis	titin	0.0007	0.0061	0.0061
Echinococcus multilocularis	Peptidase C19, ubiquitin carboxyl terminal hydrolase 2	0.0078	1	1
Echinococcus granulosus	ubiquitin specific protease 41	0.0078	1	1
Brugia malayi	Cytochrome P450 family protein	0.0049	0.5899	0.5899
Loa Loa (eye worm)	hypothetical protein	0.0016	0.1367	0.1367
Onchocerca volvulus		0.0016	0.1367	1
Schistosoma mansoni	cytochrome P450	0.003	0.3271	0.3271
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0078	1	1
Brugia malayi	GCC2 and GCC3 family protein	0.0016	0.1367	0.1367
Onchocerca volvulus		0.0007	0.0061	0.0448
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0007	0.0061	0.0061
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0007	0.0061	0.0061
Echinococcus multilocularis	ubiquitin specific protease 41	0.0078	1	1
Brugia malayi	hypothetical protein	0.0016	0.1367	0.1367
Loa Loa (eye worm)	hypothetical protein	0.0016	0.1367	0.1367
Loa Loa (eye worm)	hypothetical protein	0.0016	0.1367	0.1367
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.6786	0.6786
Echinococcus granulosus	titin	0.0007	0.0061	0.0061
Schistosoma mansoni	hypothetical protein	0.0007	0.0061	0.0061
Echinococcus granulosus	cytochrome P450 2K1	0.003	0.3271	0.3271
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.6786	0.6786
Loa Loa (eye worm)	hypothetical protein	0.0007	0.0061	0.0061
Brugia malayi	cytochrome P450	0.003	0.3271	0.3271
Echinococcus multilocularis	roundabout 2	0.0007	0.0061	0.0061
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0007	0.0061	0.0061
Schistosoma mansoni	cell adhesion molecule	0.0007	0.0061	0.0061
Brugia malayi	hypothetical protein	0.0016	0.1367	0.1367
Brugia malayi	Sushi domain	0.0016	0.1367	0.1367
Entamoeba histolytica	hypothetical protein	0.0043	0.515	0.515
Mycobacterium tuberculosis	Probable cytochrome P450 monooxygenase 142 Cyp142	0.003	0.3271	0.5
Brugia malayi	Cytochrome P450 family protein	0.003	0.3271	0.3271
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 8	0.0078	1	1
Schistosoma mansoni	cell adhesion molecule	0.0007	0.0061	0.0061
Brugia malayi	hypothetical protein	0.0016	0.1367	0.1367
Schistosoma mansoni	cell adhesion molecule	0.0007	0.0061	0.0061
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0078	1	1
Toxoplasma gondii	cytochrome p450 superfamily protein	0.003	0.3271	1
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	0.0078	1	1
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 8	0.0078	1	1
Entamoeba histolytica	hypothetical protein	0.0043	0.515	0.515
Mycobacterium tuberculosis	Possible cytochrome P450 135A1 Cyp135A1	0.003	0.3271	0.5
Echinococcus granulosus	roundabout 2	0.0007	0.0061	0.0061
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0007	0.0061	0.0061
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0055	0.6786	0.6786
Brugia malayi	hypothetical protein	0.0016	0.1367	0.1367
Leishmania major	cytochrome p450-like protein	0.003	0.3271	0.3271
Echinococcus granulosus	c4b binding protein beta chain	0.0016	0.1367	0.1367
Trypanosoma cruzi	Lanosterol 14-alpha demethylase	0.003	0.3271	0.3271
Brugia malayi	hypothetical protein	0.0016	0.1367	0.1367
Mycobacterium tuberculosis	Probable cytochrome P450 123 Cyp123	0.003	0.3271	0.5
Echinococcus multilocularis	c4b binding protein beta chain	0.0016	0.1367	0.1367
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.0007	0.0061	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0007	0.0061	0.0061
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0078	1	1
Mycobacterium tuberculosis	Cytochrome P450 121 Cyp121	0.003	0.3271	0.5
Mycobacterium tuberculosis	Probable cytochrome P450 125 Cyp125	0.003	0.3271	0.5
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.0061	0.0061
Schistosoma mansoni	myosin-binding protein-related	0.0007	0.0061	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0016	0.1367	0.1367
Mycobacterium tuberculosis	Probable cytochrome P450 130 Cyp130	0.003	0.3271	0.5
Loa Loa (eye worm)	cytochrome P450 family protein	0.0058	0.7201	0.7201
Entamoeba histolytica	hypothetical protein	0.0043	0.515	0.515
Echinococcus multilocularis	neuroglian	0.0007	0.0061	0.0061
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0078	1	1
Loa Loa (eye worm)	hypothetical protein	0.0016	0.1367	0.1367
Leishmania major	cytochrome p450-like protein	0.003	0.3271	0.3271
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0055	0.6786	0.6786
Leishmania major	cytochrome p450-like protein	0.0058	0.7201	0.7201
Toxoplasma gondii	rhoptry neck protein RON1	0.0016	0.1367	0.4179
Schistosoma mansoni	nephrin	0.0007	0.0061	0.0061
Mycobacterium leprae	Conserved hypothetical protein	0.003	0.3271	0.5
Plasmodium falciparum	apical sushi protein	0.0016	0.1367	1
Echinococcus granulosus	Peptidase C19 ubiquitin carboxyl terminal hydrolase 2	0.0078	1	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.0061	0.0061
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.6786	0.6786
Echinococcus granulosus	roundabout 2	0.0007	0.0061	0.0061
Onchocerca volvulus		0.0007	0.0061	0.0448
Schistosoma mansoni	nephrin	0.0007	0.0061	0.0061
Trypanosoma cruzi	Lanosterol 14-alpha demethylase	0.003	0.3271	0.3271
Mycobacterium tuberculosis	Probable cytochrome P450 140 Cyp140	0.003	0.3271	0.5
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0007	0.0061	0.0061
Schistosoma mansoni	hypothetical protein	0.003	0.3271	0.3271
Trypanosoma cruzi	cytochrome P450, putative	0.0058	0.7201	0.7201
Echinococcus multilocularis	C type lectin domian containing protein	0.0016	0.1367	0.1367
Onchocerca volvulus		0.0016	0.1367	1
Schistosoma mansoni	cell adhesion molecule	0.0007	0.0061	0.0061
Schistosoma mansoni	transcription factor LCR-F1	0.0043	0.515	0.515
Schistosoma mansoni	neuroglian	0.0007	0.0061	0.0061
Brugia malayi	hypothetical protein	0.0016	0.1367	0.1367
Loa Loa (eye worm)	cytochrome P450 family protein	0.0049	0.5899	0.5899
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.0061	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0016	0.1367	0.1367
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.0061	0.0061
Toxoplasma gondii	rhoptry neck protein RON9	0.0016	0.1367	0.4179
Schistosoma mansoni	hypothetical protein	0.0043	0.515	0.515
Plasmodium vivax	apical sushi protein, putative	0.0016	0.1367	1
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0007	0.0061	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0018	0.1619	0.1619
Brugia malayi	protein unc-22	0.0007	0.0061	0.0061
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0078	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0078	1	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.0061	0.0061
Mycobacterium tuberculosis	Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM)	0.003	0.3271	0.5
Schistosoma mansoni	c4b-binding protein beta chain	0.0016	0.1367	0.1367
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.0061	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0016	0.1367	0.1367
Schistosoma mansoni	serine/threonine protein kinase	0.0007	0.0061	0.0061
Mycobacterium tuberculosis	Probable cytochrome P450 138 Cyp138	0.003	0.3271	0.5
Mycobacterium tuberculosis	Probable cytochrome P450 143 Cyp143	0.003	0.3271	0.5
Onchocerca volvulus		0.0016	0.1367	1
Echinococcus granulosus	neuroglian	0.0007	0.0061	0.0061
Loa Loa (eye worm)	cytochrome P450 family protein	0.0058	0.7201	0.7201
Onchocerca volvulus		0.0016	0.1367	1
Trypanosoma cruzi	cytochrome p450-like protein, putative	0.003	0.3271	0.3271
Mycobacterium tuberculosis	Probable cytochrome P450 132 Cyp132	0.003	0.3271	0.5
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0007	0.0061	0.0061
Trypanosoma brucei	cytochrome P450, putative	0.0058	0.7201	0.7201
Onchocerca volvulus		0.0016	0.1367	1
Brugia malayi	hypothetical protein	0.0016	0.1367	0.1367
Entamoeba histolytica	hypothetical protein	0.0043	0.515	0.515
Mycobacterium tuberculosis	Possible cytochrome P450 126 Cyp126	0.003	0.3271	0.5
Brugia malayi	hypothetical protein	0.0043	0.515	0.515
Brugia malayi	pregnancy-associated plasma protein-A	0.0016	0.1367	0.1367
Echinococcus multilocularis	transfer RNA-Phe	0.0007	0.0061	0.0061
Mycobacterium tuberculosis	Possible cytochrome P450 135B1 Cyp135B1	0.003	0.3271	0.5
Echinococcus granulosus	nephrin	0.0007	0.0061	0.0061
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0043	0.515	0.515
Trypanosoma brucei	Lanosterol 14-alpha demethylase	0.003	0.3271	0.3271
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.0061	0.0061
Loa Loa (eye worm)	cytochrome P450	0.003	0.3271	0.3271
Leishmania major	lanosterol 14-alpha-demethylase, putative	0.003	0.3271	0.3271
Echinococcus granulosus	roundabout 2	0.0007	0.0061	0.0061
Onchocerca volvulus		0.0016	0.1367	1
Echinococcus multilocularis	contactin neuroglian septate junction protein	0.0007	0.0061	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0007	0.0061	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0078	1	1
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0055	0.6786	0.6786
Schistosoma mansoni	titin	0.0007	0.0061	0.0061
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0055	0.6786	0.6786
Mycobacterium tuberculosis	Probable cytochrome P450 144 Cyp144	0.003	0.3271	0.5
Echinococcus granulosus	C type lectin domian containing protein	0.0016	0.1367	0.1367
Trypanosoma cruzi	cytochrome P450, putative	0.0058	0.7201	0.7201
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0055	0.6786	0.6786
Mycobacterium leprae	putative cytochrome p450	0.003	0.3271	0.5
Schistosoma mansoni	ubiquitin-specific peptidase 8 (C19 family)	0.0078	1	1
Loa Loa (eye worm)	CAMK protein kinase	0.0007	0.0061	0.0061
Loa Loa (eye worm)	projectin	0.0007	0.0061	0.0061
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0007	0.0061	0.0061
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0078	1	1
Echinococcus granulosus	titin	0.0007	0.0061	0.0061
Mycobacterium tuberculosis	Probable cytochrome P450 139 Cyp139	0.003	0.3271	0.5
Mycobacterium tuberculosis	Probable cytochrome P450 141 Cyp141	0.003	0.3271	0.5

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	0.5174 uM	PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648]	ChEMBL.	No reference
Potency (functional)	6.3096 uM	PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	15.8489 uM	PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249]	ChEMBL.	No reference
Potency (functional)	= 23.7558 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))]	ChEMBL.	No reference
Potency (functional)	28.1838 uM	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398]	ChEMBL.	No reference
Potency (functional)	= 56.2341 um	PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))]	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Homo sapiens	ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1596043

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1447754