Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0058 | 0.1231 | 0.2506 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0058 | 0.1231 | 0.353 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.1557 | 0.3171 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.1557 | 0.1563 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0941 | 0.1915 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0058 | 0.1231 | 0.1235 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0163 | 0.4569 | 0.4569 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0072 | 0.1697 | 0.1703 |
Schistosoma mansoni | coup transcription factor | 0.0058 | 0.1231 | 0.2506 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0022 | 0.0092 | 0.1764 |
Echinococcus granulosus | tumor protein p63 | 0.0332 | 0.9967 | 1 |
Onchocerca volvulus | Poor gastrulation protein homolog | 0.0033 | 0.0441 | 0.1264 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0099 | 0.254 | 0.254 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0139 | 0.3828 | 0.3828 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0132 | 0.3598 | 0.3598 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0052 | 0.1048 | 0.1048 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0049 | 0.0942 | 0.1919 |
Brugia malayi | MH2 domain containing protein | 0.0139 | 0.3828 | 0.3828 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0519 | 1 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0129 | 0.3503 | 0.3515 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0022 | 0.0092 | 0.0092 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0049 | 0.0942 | 0.0945 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0027 | 0.026 | 0.0261 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.1557 | 0.1557 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0099 | 0.254 | 0.5171 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0092 | 0.5 |
Onchocerca volvulus | 0.003 | 0.0344 | 0.0987 | |
Echinococcus granulosus | FTZ F1 alpha | 0.0058 | 0.1231 | 0.1235 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0022 | 0.0092 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0027 | 0.026 | 0.026 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0441 | 0.0898 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1245 | 0.1245 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0027 | 0.026 | 0.0261 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0058 | 0.1231 | 0.1235 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0.0092 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0058 | 0.1231 | 0.1235 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0052 | 0.1048 | 0.1048 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.3482 | 0.3482 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | nuclear receptor NHR-88 | 0.0027 | 0.026 | 0.026 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0058 | 0.1231 | 0.2506 |
Loa Loa (eye worm) | glutamate receptor | 0.0082 | 0.199 | 0.199 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0058 | 0.1231 | 0.1235 |
Brugia malayi | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Onchocerca volvulus | 0.0027 | 0.026 | 0.0745 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0092 | 1 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.3702 | 0.3702 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0027 | 0.026 | 0.026 |
Brugia malayi | tailless protein | 0.0027 | 0.026 | 0.026 |
Brugia malayi | nuclear receptor RXR | 0.003 | 0.0364 | 0.0364 |
Brugia malayi | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0519 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.1557 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0058 | 0.1231 | 0.1231 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0698 | 0.2003 |
Schistosoma mansoni | nuclear hormone receptor | 0.0027 | 0.026 | 0.0529 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0027 | 0.026 | 0.026 |
Brugia malayi | ecdysone receptor | 0.0027 | 0.026 | 0.026 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0155 | 0.4316 | 0.8787 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0173 | 0.4912 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0163 | 0.4569 | 0.4584 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0163 | 0.4569 | 0.4584 |
Schistosoma mansoni | nuclear hormone receptor | 0.0027 | 0.026 | 0.0529 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0027 | 0.026 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0659 | 0.0659 |
Brugia malayi | bHLH-PAS transcription factor | 0.0044 | 0.0801 | 0.0801 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.0128 | 0.3482 | 0.3494 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0058 | 0.1231 | 0.1231 |
Toxoplasma gondii | exonuclease III APE | 0.0022 | 0.0092 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0027 | 0.026 | 0.0261 |
Onchocerca volvulus | 0.0058 | 0.1231 | 0.353 | |
Brugia malayi | hypothetical protein | 0.0035 | 0.0519 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0139 | 0.3828 | 0.3828 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0092 | 0.0186 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0058 | 0.1231 | 0.1235 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.003 | 0.0364 | 0.0365 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0058 | 0.1231 | 0.1235 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0027 | 0.026 | 0.0261 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | conserved hypotetical protein | 0.0027 | 0.026 | 0.026 |
Onchocerca volvulus | 0.0049 | 0.0941 | 0.2698 | |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.1557 | 0.1563 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.0128 | 0.3482 | 0.3494 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0941 | 0.0941 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0058 | 0.1231 | 0.1235 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0058 | 0.1231 | 0.2506 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0606 | 0.3511 |
Echinococcus multilocularis | GPCR, family 3, C terminal | 0.0033 | 0.0441 | 0.0442 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0124 | 0.3345 | 0.3356 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0022 | 0.0092 | 0.0092 |
Onchocerca volvulus | Metabotropic glutamate receptor homolog | 0.0033 | 0.0441 | 0.1264 |
Brugia malayi | nuclear hormone receptor | 0.0027 | 0.026 | 0.026 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.1245 | 0.1245 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Onchocerca volvulus | 0.0027 | 0.026 | 0.0745 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.003 | 0.0364 | 0.0365 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0606 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.2992 | 0.2992 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0082 | 0.199 | 0.199 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0058 | 0.1231 | 0.1231 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0252 | 0.1094 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0027 | 0.026 | 0.026 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0364 | 0.0364 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0027 | 0.026 | 0.026 |
Schistosoma mansoni | single-minded | 0.006 | 0.1296 | 0.2638 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | steroid hormone receptor | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0044 | 0.0801 | 0.0804 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | tumor protein p63 | 0.0332 | 0.9967 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0027 | 0.026 | 0.0529 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0027 | 0.026 | 0.0529 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0092 | 0.5 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0027 | 0.026 | 0.0261 |
Loa Loa (eye worm) | DR-78 | 0.0027 | 0.026 | 0.026 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0027 | 0.026 | 0.026 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.1245 | 0.1245 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0058 | 0.1231 | 0.1235 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Schistosoma mansoni | nuclear receptor | 0.0027 | 0.026 | 0.0529 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.1245 | 0.1245 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0063 | 0.1383 | 0.1383 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.1557 | 0.1563 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0058 | 0.1231 | 0.1231 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0109 | 0.2875 | 0.5854 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.0659 | 0.0659 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0058 | 0.1231 | 0.1235 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0027 | 0.026 | 0.0261 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0606 | 0.0606 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0058 | 0.1231 | 0.2506 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0659 | 0.1341 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0052 | 0.1048 | 0.1048 |
Echinococcus granulosus | GPCR family 3 C terminal | 0.0033 | 0.0441 | 0.0442 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0698 | 0.414 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0027 | 0.026 | 0.0261 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0252 | 0.1094 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0.0092 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.0027 | 0.026 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.3487 | 0.3487 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0049 | 0.0942 | 0.0945 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0113 | 0.2992 | 0.2992 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0.0092 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0058 | 0.1231 | 0.1235 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.1557 | 0.1563 |
Schistosoma mansoni | thyroid hormone receptor | 0.0058 | 0.1231 | 0.2506 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3009 | 0.3009 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0519 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.003 | 0.0364 | 0.0741 |
Onchocerca volvulus | 0.0045 | 0.0818 | 0.2345 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0027 | 0.026 | 0.0745 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.1557 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0519 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0022 | 0.0092 | 1 |
Brugia malayi | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | glutamate receptor | 0.008 | 0.1933 | 0.1933 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0519 | 0.1056 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0058 | 0.1231 | 0.1235 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0058 | 0.1231 | 0.353 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0364 | 0.0364 |
Mycobacterium ulcerans | putative regulatory protein | 0.0044 | 0.0801 | 1 |
Brugia malayi | nuclear receptor NHR-67 | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1048 | 0.1048 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.003 | 0.0364 | 0.0364 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0155 | 0.4316 | 0.433 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0033 | 0.0441 | 0.0441 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0027 | 0.026 | 0.0529 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.003 | 0.0364 | 0.0741 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0027 | 0.026 | 0.0745 |
Brugia malayi | nuclear receptor RXR | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.1557 | 0.1557 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0058 | 0.1231 | 0.353 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0.0092 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0519 | 0.1056 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0058 | 0.1231 | 0.1235 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | nuclear hormone receptor | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0092 | 0.0186 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0072 | 0.1697 | 0.1703 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0058 | 0.1231 | 0.2506 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0606 | 0.0606 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0058 | 0.1231 | 0.2506 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0606 | 0.1739 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0344 | 0.0344 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.1557 | 0.3171 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0519 | 0.0521 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0698 | 0.414 |
Brugia malayi | PAS domain containing protein | 0.006 | 0.1296 | 0.1296 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0022 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0058 | 0.1231 | 0.1231 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0058 | 0.1231 | 0.1235 |
Schistosoma mansoni | nuclear receptor | 0.0027 | 0.026 | 0.0529 |
Echinococcus granulosus | single minded 2 | 0.0044 | 0.0801 | 0.0804 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0129 | 0.3503 | 0.3515 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0027 | 0.026 | 0.0261 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0364 | 0.0364 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0058 | 0.1231 | 0.1235 |
Onchocerca volvulus | 0.0129 | 0.3487 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0058 | 0.1231 | 0.1231 |
Schistosoma mansoni | nuclear hormone receptor | 0.0058 | 0.1231 | 0.2506 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0027 | 0.026 | 0.0261 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0058 | 0.1231 | 0.2506 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0058 | 0.1231 | 0.2506 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0058 | 0.1231 | 0.1231 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0092 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0058 | 0.1231 | 0.2506 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0058 | 0.1231 | 0.1231 |
Brugia malayi | nuclear receptor NHR-88 | 0.0058 | 0.1231 | 0.1231 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0027 | 0.026 | 0.0261 |
Brugia malayi | ecdysteroid receptor | 0.0058 | 0.1231 | 0.1231 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0441 | 0.0441 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0519 | 0.0521 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.026 | 0.026 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 63.0957 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): qHTS. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 100 um | PUBCHEM_BIOASSAY: Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.