Detailed information for compound 1448740

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 331.325 | Formula: C19H13N3O3
  • H donors: 2 H acceptors: 3 LogP: 2.76 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1ccc(cc1)c1ccc(o1)C1Nc2ccccc2C(=O)N1O
  • InChi: 1S/C19H13N3O3/c20-11-12-5-7-13(8-6-12)16-9-10-17(25-16)18-21-15-4-2-1-3-14(15)19(23)22(18)24/h1-10,18,21,24H
  • InChiKey: KUTPFZWXNQRAHY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Schistosoma mansoni Thioredoxin glutathione reductase Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Rattus norvegicus Thioredoxin reductase 1, cytoplasmic Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium yoelii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus multilocularis thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania mexicana trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi Thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Echinococcus granulosus thioredoxin glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania donovani trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania infantum trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Brugia malayi glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum MGC84926 protein, related Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium knowlesi glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax glutathione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Toxoplasma gondii thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Candida albicans similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium hominis thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Schistosoma japonicum ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative Get druggable targets OG5_126785 All targets in OG5_126785
Theileria parva thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania major trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium falciparum glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium vivax thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Leishmania braziliensis trypanothione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium yoelii glutathione reductase Get druggable targets OG5_126785 All targets in OG5_126785
Neospora caninum Glutathione reductase, related Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma congolense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Babesia bovis thiodoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Plasmodium berghei thioredoxin reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma cruzi trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Loa Loa (eye worm) thioredoxin reductase Get druggable targets OG5_126785 All targets in OG5_126785
Trypanosoma brucei gambiense trypanothione reductase, putative Get druggable targets OG5_126785 All targets in OG5_126785
Cryptosporidium parvum thioredoxin reductase 1 Get druggable targets OG5_126785 All targets in OG5_126785
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Neospora caninum hypothetical protein Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.0 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.3 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.5 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 540 aa 23.3 %
Leishmania mexicana 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 452 aa 25.7 %
Onchocerca volvulus Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 57.3 %
Leishmania braziliensis acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 22.8 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.2 %
Leishmania infantum dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.5 %
Trypanosoma brucei dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 23.4 %
Leishmania donovani acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 460 aa 25.4 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.9 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.2 %
Leishmania mexicana acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 499 aa 24.4 %
Neospora caninum Dihydrolipoyl dehydrogenase (EC 1.8.1.4), related Thioredoxin reductase 1, cytoplasmic   499 aa 464 aa 24.8 %
Leishmania major acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II Thioredoxin reductase 1, cytoplasmic   499 aa 448 aa 27.2 %
Trypanosoma congolense dihydrolipoamide dehydrogenase, point mutation, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Plasmodium berghei dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 539 aa 22.3 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 519 aa 23.7 %
Plasmodium falciparum glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 500 aa 32.2 %
Leishmania infantum acetoin dehydrogenase e3 component-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 497 aa 24.1 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 489 aa 22.7 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast Thioredoxin reductase 1, cytoplasmic   499 aa 506 aa 23.7 %
Leishmania donovani dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 466 aa 20.6 %
Plasmodium berghei dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 26.9 %
Plasmodium falciparum thioredoxin reductase Thioredoxin reductase 1, cytoplasmic   499 aa 511 aa 45.2 %
Leishmania braziliensis dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 488 aa 21.9 %
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 483 aa 23.0 %
Plasmodium knowlesi dihydrolipoyl dehydrogenase, mitochondrial, putative Thioredoxin reductase 1, cytoplasmic   499 aa 462 aa 25.8 %
Toxoplasma gondii NADPH-glutathione reductase Thioredoxin reductase 1, cytoplasmic   499 aa 529 aa 31.8 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, point mutation,acetoin dehydrogenase e3 component, putative Thioredoxin reductase 1, cytoplasmic   499 aa 490 aa 23.3 %
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.3 %
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 454 aa 25.3 %
Neospora caninum glutathione reductase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 492 aa 32.7 %
Leishmania braziliensis 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein Thioredoxin reductase 1, cytoplasmic   499 aa 450 aa 25.6 %
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative Thioredoxin reductase 1, cytoplasmic   499 aa 518 aa 24.9 %
Trypanosoma brucei gambiense dihydrolipoamide dehydrogenase, putative Thioredoxin reductase 1, cytoplasmic   499 aa 491 aa 23.6 %
Plasmodium yoelii dihydrolipoamide dehydrogenase Thioredoxin reductase 1, cytoplasmic   499 aa 465 aa 27.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus neutral amino acid transporter A 0.0765 0.9534 0.9534
Echinococcus multilocularis glutamate receptor 2 0.0413 0.356 0.356
Echinococcus granulosus excitatory amino acid transporter 3 0.0765 0.9534 0.9534
Schistosoma mansoni glutamate receptor kainate 0.037 0.2829 0.23
Echinococcus granulosus sodium:dicarboxylate symporter 0.0765 0.9534 0.9534
Echinococcus multilocularis neutral amino acid transporter A 0.0765 0.9534 0.9534
Schistosoma mansoni glutamate receptor kainate 0.0677 0.8041 0.8285
Schistosoma mansoni glutamate receptor AMPA 0.037 0.2829 0.23
Brugia malayi Glutamate receptor 2 precursor 0.0413 0.356 0.3139
Echinococcus granulosus excitatory amino acid transporter 2 0.0765 0.9534 0.9534
Echinococcus multilocularis Excitatory amino acid transporter 0.0765 0.9534 0.9534
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0261 0.0965 0.0493
Schistosoma mansoni glutamate receptor NMDA 0.0486 0.4788 0.455
Echinococcus granulosus excitatory amino acid transporter 2 0.0765 0.9534 0.9534
Brugia malayi Metabotropic glutamate receptor precursor. 0.0431 0.3864 0.3489
Schistosoma mansoni glutamate receptor AMPA 0.037 0.2829 0.23
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0588 0.6531 0.6531
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0765 0.9534 0.9534
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0316 0.1905 0.1239
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0339 0.2297 0.1689
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0792 1 1
Brugia malayi Glutamate receptor 1 precursor 0.0413 0.356 0.3139
Loa Loa (eye worm) glutamate receptor 0.0431 0.3864 0.1544
Loa Loa (eye worm) glutamate receptor 1 0.0413 0.356 0.1089
Echinococcus granulosus glutamate NMDA receptor subunit 0.037 0.2829 0.2829
Schistosoma mansoni metabotropic glutamate receptor 0.0375 0.2902 0.2384
Echinococcus granulosus glutamate receptor 2 0.0529 0.5519 0.5519
Echinococcus multilocularis neutral amino acid transporter A 0.0765 0.9534 0.9534
Schistosoma mansoni solute carrier family 1 (glial high affinity glutamate transporter 0.0765 0.9534 1
Mycobacterium tuberculosis Probable C4-dicarboxylate-transport transmembrane protein DctA 0.0765 0.9534 1
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0339 0.2297 0.2297
Onchocerca volvulus Excitatory amino acid transporter homolog 0.0765 0.9534 0.5
Echinococcus granulosus neutral amino acid transporter A 0.0765 0.9534 0.9534
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0468 0.4481 0.4481
Echinococcus multilocularis Excitatory amino acid transporter 0.0765 0.9534 0.9534
Schistosoma mansoni ATP-binding cassette transporter 0.037 0.2829 0.23
Wolbachia endosymbiont of Brugia malayi Na+/H+-dicarboxylate symporter 0.0765 0.9534 0.5
Echinococcus granulosus glutamate receptor 2 0.0368 0.2784 0.2784
Echinococcus multilocularis excitatory amino acid transporter 3 0.0765 0.9534 0.9534
Echinococcus multilocularis glutamate receptor 2 0.0529 0.5519 0.5519
Schistosoma mansoni glutamate receptor NMDA 0.037 0.2829 0.23
Echinococcus multilocularis sodium:dicarboxylate symporter 0.0339 0.2297 0.2297
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0792 1 1
Treponema pallidum glutamate/aspartate transporter 0.0339 0.2297 0.5
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0468 0.4481 0.4481
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0529 0.5519 0.5519
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.037 0.2829 0.2829
Mycobacterium tuberculosis Probable oxidoreductase 0.0261 0.0965 0.0493
Echinococcus granulosus nmda type glutamate receptor 0.0281 0.1319 0.1319
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0792 1 1
Echinococcus multilocularis glutamate receptor 2 0.0368 0.2784 0.2784
Echinococcus granulosus Excitatory amino acid transporter 0.0765 0.9534 0.9534
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0397 0.3275 0.2812
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0792 1 1
Echinococcus granulosus neutral amino acid transporter 0.0765 0.9534 0.9534
Echinococcus multilocularis neutral amino acid transporter A 0.0765 0.9534 0.9534
Echinococcus multilocularis NMDA receptor 0.0468 0.4481 0.4481
Schistosoma mansoni sodium/dicarboxylate symporter-related 0.0339 0.2297 0.1689
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0468 0.4481 0.4481
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0529 0.5519 0.5519
Echinococcus granulosus metabotropic glutamate receptor 5 0.0512 0.5234 0.5234
Echinococcus multilocularis excitatory amino acid transporter 2 0.0765 0.9534 0.9534
Loa Loa (eye worm) hypothetical protein 0.0512 0.5234 0.3587
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0261 0.0965 1
Treponema pallidum glutamate transporter 0.0339 0.2297 0.5
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0512 0.5234 0.5234
Echinococcus multilocularis nmda type glutamate receptor 0.0281 0.1319 0.1319
Echinococcus granulosus Excitatory amino acid transporter 0.0765 0.9534 0.9534
Echinococcus multilocularis neutral amino acid transporter excitatory amino acid transporter 0.0765 0.9534 0.9534
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0261 0.0965 0.0493
Brugia malayi Excitatory amino acid transporter 0.0765 0.9534 1
Loa Loa (eye worm) excitatory amino acid transporter 0.0765 0.9534 1
Echinococcus granulosus metabotropic glutamate receptor 2 0.0375 0.2902 0.2902
Chlamydia trachomatis glutamate symporter 0.0765 0.9534 1
Schistosoma mansoni glutamate receptor kainate 0.0677 0.8041 0.8285
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0375 0.2902 0.2902
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0792 1 1
Echinococcus multilocularis excitatory amino acid transporter 2 0.0765 0.9534 0.9534

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.6626 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 4.4668 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 7.0795 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 22.3872 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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