Detailed information for compound 1449233

Basic information

Technical information
  • TDR Targets ID: 1449233
  • Name: 4-(2,3-diethyl-7,8-dihydro-5H-1,6-naphthyridi n-6-yl)-N-[[(2R,3S,6S)-3-(4-methoxyphenoxy)-6 -phenyl-3,6-dihydro-2H-pyran-2-yl]methoxy]but an-2-imine
  • MW: 569.734 | Formula: C35H43N3O4
  • H donors: 0 H acceptors: 1 LogP: 6.14 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 2
  • SMILES: COc1ccc(cc1)O[C@H]1C=C[C@H](O[C@@H]1CO/N=C(/CCN1CCc2c(C1)cc(c(n2)CC)CC)\C)c1ccccc1
  • InChi: 1S/C35H43N3O4/c1-5-26-22-28-23-38(21-19-32(28)36-31(26)6-2)20-18-25(3)37-40-24-35-34(41-30-14-12-29(39-4)13-15-30)17-16-33(42-35)27-10-8-7-9-11-27/h7-17,22,33-35H,5-6,18-21,23-24H2,1-4H3/b37-25+/t33-,34-,35+/m0/s1
  • InChiKey: FAYBCRHOKZVQOA-ZZTVCBIESA-N  


Substructure search Similarity search

Network

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Synonyms

  • [3-(2,3-diethyl-7,8-dihydro-5H-1,6-naphthyridin-6-yl)-1-methyl-propylidene]-[[(2R,3S,6S)-3-(4-methoxyphenoxy)-6-phenyl-3,6-dihydro-2H-pyran-2-yl]methoxy]amine
  • (E)-[3-(2,3-diethyl-7,8-dihydro-5H-1,6-naphthyridin-6-yl)-1-methyl-propylidene]-[[(2R,3S,6S)-3-(4-methoxyphenoxy)-6-phenyl-3,6-dihydro-2H-pyran-2-yl]methoxy]amine
  • SMR000113049
  • CMLDBU00002248
  • NCGC00017702-01
  • MLS000439044
  • CMLD2_000645

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 9 Starlite/ChEMBL No references
Bacillus anthracis Anthrax lethal factor Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens mitogen-activated protein kinase 1 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily C, polypeptide 19 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 6 Starlite/ChEMBL No references
Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 Starlite/ChEMBL No references
Homo sapiens huntingtin Starlite/ChEMBL No references
Homo sapiens glucosidase, beta, acid Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Echinococcus multilocularis mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania donovani mitogen activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania mexicana mitogen-activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trypanosoma congolense tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein Get druggable targets OG5_129423 All targets in OG5_129423
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi O-Glycosyl hydrolase family 30 protein Get druggable targets OG5_129423 All targets in OG5_129423
Giardia lamblia Kinase, CMGC MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Onchocerca volvulus Huntingtin homolog Get druggable targets OG5_132837 All targets in OG5_132837
Cryptosporidium hominis MAPK Get druggable targets OG5_126781 All targets in OG5_126781
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus granulosus mitogen activated protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium parvum MAPK, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma cruzi mitogen activated protein kinase 2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania donovani cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense protein kinase, putative,tyrosine protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Candida albicans Serine/threonine protein kinase of MAP kinase family Get druggable targets OG5_126781 All targets in OG5_126781
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania infantum mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Candida albicans cytochrome P450 56 Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi MAP kinase sur-1 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania major cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Onchocerca volvulus Huntingtin homolog Get druggable targets OG5_132837 All targets in OG5_132837
Leishmania braziliensis mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trypanosoma brucei gambiense mitogen-activated protein kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum Mitogen-activated protein kinase 3, putative Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania braziliensis cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Candida albicans cytochrome P450 556 Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans MAP kinase implicated in PKC1-controlled signalling pathway Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Trypanosoma brucei gambiense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) CYP4Cod1 Get druggable targets OG5_126554 All targets in OG5_126554
Onchocerca volvulus Glucosylceramidase homolog Get druggable targets OG5_129423 All targets in OG5_129423
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126582 All targets in OG5_126582
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus multilocularis mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Brugia malayi hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Trypanosoma cruzi mitogen-activated protein kinase 11, putative Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans MAP kinase-like orf Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Leishmania major mitogen activated protein kinase, putative,map kinase, putative Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Leishmania mexicana cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Echinococcus granulosus mitogen activated protein kinase 3 Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trichomonas vaginalis CMGC family protein kinase Get druggable targets OG5_126781 All targets in OG5_126781
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Trypanosoma brucei mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Schistosoma japonicum ko:K04371 extracellular signal-regulated kinase 1/2, putative Get druggable targets OG5_126781 All targets in OG5_126781
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma cruzi mitogen activated protein kinase 4, putative Get druggable targets OG5_126781 All targets in OG5_126781
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis glucosylceramidase, putative Get druggable targets OG5_129423 All targets in OG5_129423
Leishmania donovani mitogen-activated protein kinase 4 Get druggable targets OG5_126781 All targets in OG5_126781
Leishmania infantum mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 Get druggable targets OG5_126781 All targets in OG5_126781
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi cytochrome P450 cytochrome P450, family 3, subfamily A, polypeptide 4 502 aa 492 aa 24.2 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Leishmania major cytochrome p450-like protein cytochrome P450, family 2, subfamily C, polypeptide 19 490 aa 411 aa 23.1 %
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 cytochrome P450, family 2, subfamily C, polypeptide 9 490 aa 441 aa 21.8 %
Brugia malayi cytochrome P450 cytochrome P450, family 2, subfamily D, polypeptide 6 497 aa 425 aa 32.0 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 1 360 aa 361 aa 33.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0177 0.1649 0.3069
Giardia lamblia Hypothetical protein 0.0099 0.0836 1
Loa Loa (eye worm) inositol-1 0.0038 0.0207 0.0386
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0099 0.0836 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0535 0.5374 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0535 0.5374 1
Echinococcus multilocularis serotonin receptor 0.0126 0.1118 0.1118
Brugia malayi Cathepsin L-like precursor 0.0535 0.5374 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0836 0.1556
Onchocerca volvulus Cathepsin L homolog 0.0535 0.5374 1
Entamoeba histolytica cysteine proteinase, putative 0.0275 0.2676 0.4936
Onchocerca volvulus Huntingtin homolog 0.0148 0.1349 0.2298
Schistosoma mansoni lamin 0.0033 0.0148 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0099 0.0836 0.1484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0275 0.2676 0.4936
Trypanosoma cruzi cysteine peptidase, putative 0.0535 0.5374 1
Brugia malayi PHD-finger family protein 0.0027 0.0088 0.0079
Loa Loa (eye worm) cysteine protease 0.0535 0.5374 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0535 0.5374 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0275 0.2676 0.4936
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0535 0.5374 0.5374
Brugia malayi hypothetical protein 0.0148 0.1349 0.2446
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0275 0.2676 0.4936
Entamoeba histolytica cysteine proteinase, putative 0.0275 0.2676 0.4936
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0099 0.0836 0.1484
Echinococcus granulosus cathepsin b 0.0099 0.0836 0.0986
Schistosoma mansoni biogenic amine (5HT) receptor 0.0374 0.3701 0.4363
Echinococcus multilocularis cysteine protease 0.0535 0.5374 0.5374
Brugia malayi Cathepsin L-like precursor 0.0358 0.3534 0.6547
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.004 0.0074
Giardia lamblia Hypothetical protein 0.0099 0.0836 1
Schistosoma mansoni ap endonuclease 0.0023 0.0046 0.0054
Plasmodium falciparum cysteine proteinase falcipain 3 0.0535 0.5374 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0836 0.1556
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0535 0.5374 1
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Loa Loa (eye worm) hypothetical protein 0.0099 0.0836 0.1556
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3055 0.5648
Entamoeba histolytica hypothetical protein 0.008 0.0646 0.1126
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0535 0.5374 1
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0099 0.0836 0.1484
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0099 0.0836 0.1484
Brugia malayi Cathepsin L-like precursor 0.0358 0.3534 0.6547
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0098 0.3198
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0099 0.0836 0.1484
Schistosoma mansoni cathepsin F (C01 family) 0.0535 0.5374 0.6336
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Loa Loa (eye worm) hypothetical protein 0.0099 0.0836 0.1556
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0476 0.0476
Giardia lamblia Cathepsin B precursor 0.0099 0.0836 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0535 0.5374 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0148 0.0276
Giardia lamblia Cysteine protease 0.0099 0.0836 1
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.8482 1
Entamoeba histolytica cysteine proteinase, putative 0.0275 0.2676 0.4936
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1939 0.3553
Echinococcus multilocularis geminin 0.0182 0.1702 0.1702
Leishmania major cathepsin L-like protease 0.0535 0.5374 1
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.045 0.045
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1939 0.3553
Schistosoma mansoni cathepsin s 0.0177 0.1649 0.1944
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0166 0.5
Schistosoma mansoni hypothetical protein 0.0182 0.1702 0.2007
Chlamydia trachomatis tail-specific protease 0.0264 0.2562 1
Schistosoma mansoni hypothetical protein 0.0182 0.1702 0.2007
Entamoeba histolytica hypothetical protein 0.0099 0.0836 0.1484
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3055 0.5648
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1939 0.3553
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0099 0.0836 0.0986
Brugia malayi cathepsin F-like cysteine proteinase 0.0099 0.0836 0.1484
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0099 0.0836 0.0986
Brugia malayi Cathepsin L-like precursor 0.0535 0.5374 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0207 0.0303
Plasmodium falciparum serine repeat antigen 6 0.0099 0.0836 0.1484
Loa Loa (eye worm) hypothetical protein 0.0177 0.1649 0.3069
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0177 0.1649 0.3069
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0207 0.0303
Leishmania major cysteine peptidase A (CPA) 0.0535 0.5374 1
Giardia lamblia Cathepsin L precursor 0.0099 0.0836 1
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.045 0.053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Plasmodium falciparum serine repeat antigen 2 0.0099 0.0836 0.1484
Brugia malayi Cathepsin L-like cysteine proteinase 0.0358 0.3534 0.6547
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.1939 0.3427
Schistosoma mansoni cathepsin B (C01 family) 0.0099 0.0836 0.0986
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0836 0.1484
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0099 0.0836 0.1484
Giardia lamblia Cysteine protease 0.0099 0.0836 1
Giardia lamblia Cathepsin B precursor 0.0099 0.0836 1
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0535 0.5374 1
Echinococcus granulosus zinc finger protein 0.0021 0.0028 0.0033
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3055 0.5648
Schistosoma mansoni cathepsin F (C01 family) 0.0358 0.3534 0.4167
Trypanosoma cruzi cruzipain precursor, putative 0.0535 0.5374 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.1349 0.251
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0207 1
Schistosoma mansoni intermediate filament proteins 0.0033 0.0148 0.0175
Giardia lamblia Cathepsin L precursor 0.0099 0.0836 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0286 0.0532
Echinococcus granulosus intermediate filament protein 0.0033 0.0148 0.0175
Echinococcus granulosus cathepsin L 0.0099 0.0836 0.0986
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0099 0.0836 0.1484
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0099 0.0836 0.1484
Plasmodium falciparum serine repeat antigen 9 0.0099 0.0836 0.1484
Echinococcus granulosus microtubule associated protein 2 0.0833 0.8482 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.3055 0.5648
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0099 0.0836 0.0986
Trypanosoma cruzi major cysteine proteinase, putative 0.0099 0.0836 0.1484
Trypanosoma cruzi cysteine peptidase, putative 0.0535 0.5374 1
Echinococcus granulosus cathepsin L cysteine protease 0.0275 0.2676 0.3155
Giardia lamblia Cathepsin B precursor 0.0099 0.0836 1
Loa Loa (eye worm) hypothetical protein 0.0358 0.3534 0.6577
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0099 0.0836 1
Loa Loa (eye worm) hypothetical protein 0.0177 0.1649 0.3069
Toxoplasma gondii preprocathepsin c precursor, putative 0.0099 0.0836 0.1484
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0099 0.0836 0.1484
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0099 0.0836 0.1484
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0099 0.0836 1
Trypanosoma cruzi cysteine proteinase, putative 0.0275 0.2676 0.4936
Giardia lamblia Cathepsin B precursor 0.0099 0.0836 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Trypanosoma cruzi cysteine peptidase, putative 0.0275 0.2676 0.4936
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Loa Loa (eye worm) cathepsin B 0.0099 0.0836 0.1556
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0207 0.0244
Trypanosoma cruzi cysteine peptidase, putative 0.0535 0.5374 1
Schistosoma mansoni zinc finger protein 0.0021 0.0028 0.0033
Brugia malayi Papain family cysteine protease containing protein 0.0535 0.5374 1
Brugia malayi Inositol-1 0.0038 0.0207 0.0303
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.2054 0.3768
Brugia malayi cathepsin Z-like cysteine proteinase 0.0099 0.0836 0.1484
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0148 0.0276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0836 0.1556
Brugia malayi cathepsin L-like cysteine proteinase 0.0099 0.0836 0.1484
Loa Loa (eye worm) hypothetical protein 0.0041 0.0238 0.0443
Loa Loa (eye worm) hypothetical protein 0.0044 0.0265 0.0492
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0275 0.2676 0.3155
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Echinococcus granulosus biogenic amine 5HT receptor 0.0374 0.3701 0.4363
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Plasmodium vivax unspecified product 0.0177 0.1649 0.3009
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.045 0.0758
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0099 0.0836 0.1484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Toxoplasma gondii cathepsin B 0.0099 0.0836 0.1484
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0099 0.0836 0.1556
Loa Loa (eye worm) hypothetical protein 0.0076 0.06 0.1116
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3055 0.5648
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.2054 0.3768
Giardia lamblia Encystation-specific protease 0.0099 0.0836 1
Brugia malayi Papain family cysteine protease containing protein 0.0099 0.0836 0.1484
Brugia malayi Cathepsin L-like precursor 0.0535 0.5374 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.045 0.0758
Brugia malayi cathepsin B-like cysteine proteinase 0.0099 0.0836 0.1484
Brugia malayi Cytochrome P450 family protein 0.0028 0.0098 0.0097
Schistosoma mansoni inositol monophosphatase 0.0038 0.0207 0.0244
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Leishmania major cathepsin L-like protease 0.0535 0.5374 1
Brugia malayi Cathepsin L-like precursor 0.0535 0.5374 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0177 0.1649 0.3009
Giardia lamblia Cysteine protease 0.0099 0.0836 1
Echinococcus multilocularis cathepsin b 0.0099 0.0836 0.0836
Onchocerca volvulus 0.0535 0.5374 1
Echinococcus multilocularis cathepsin L 0.0275 0.2676 0.2676
Echinococcus multilocularis lamin 0.0033 0.0148 0.0148
Brugia malayi Cytochrome P450 family protein 0.0028 0.0098 0.0097
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0098 0.0181
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0099 0.0836 0.1484
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0836 0.0986
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0211 0.0249
Onchocerca volvulus 0.0535 0.5374 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0099 0.0836 0.1484
Brugia malayi Cathepsin L-like precursor 0.0535 0.5374 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0099 0.0836 0.1484
Onchocerca volvulus Cathepsin F homolog 0.0535 0.5374 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Brugia malayi Bromodomain containing protein 0.0041 0.0237 0.0359
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Echinococcus multilocularis cysteine protease 0.0535 0.5374 0.5374
Brugia malayi Papain family cysteine protease containing protein 0.0099 0.0836 0.1484
Plasmodium falciparum serine repeat antigen 7 0.0099 0.0836 0.1484
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0207 0.0303
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Plasmodium vivax vivapain-2 0.0535 0.5374 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0099 0.0836 0.1484
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.045 0.0758
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0535 0.5374 1
Entamoeba histolytica cysteine protease, putative 0.0099 0.0836 0.1484
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0148 0.0192
Giardia lamblia Cathepsin B precursor 0.0099 0.0836 1
Plasmodium falciparum serine repeat antigen 4 0.0099 0.0836 0.1484
Schistosoma mansoni inositol monophosphatase 0.0038 0.0207 0.0244
Entamoeba histolytica cysteine protease, putative 0.0099 0.0836 0.1484
Treponema pallidum carboxyl-terminal protease (CTP) 0.0264 0.2562 1
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1939 0.3553
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0836 0.0986
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Echinococcus granulosus geminin 0.0182 0.1702 0.2007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0207 0.0303
Plasmodium vivax unspecified product 0.0275 0.2676 0.4936
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0099 0.0836 0.1484
Onchocerca volvulus 0.0535 0.5374 1
Entamoeba histolytica cysteine proteinase, putative 0.0358 0.3534 0.6547
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0098 0.0097
Brugia malayi Papain family cysteine protease containing protein 0.0275 0.2676 0.4936
Echinococcus multilocularis serotonin receptor 0.0126 0.1118 0.1118
Schistosoma mansoni ap endonuclease 0.0023 0.0046 0.0054
Plasmodium falciparum serine repeat antigen 1 0.0099 0.0836 0.1484
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.045 0.0758
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Trypanosoma brucei cysteine peptidase C (CPC) 0.0099 0.0836 0.1484
Echinococcus granulosus cathepsin l1 0.0535 0.5374 0.6336
Entamoeba histolytica cysteine proteinase, putative 0.0535 0.5374 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0836 0.0986
Loa Loa (eye worm) hypothetical protein 0.0032 0.0142 0.0265
Giardia lamblia Cathepsin L precursor 0.0099 0.0836 1
Onchocerca volvulus 0.0535 0.5374 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0836 0.0986
Entamoeba histolytica cysteine proteinase, putative 0.0275 0.2676 0.4936
Loa Loa (eye worm) cytochrome P450 family protein 0.0063 0.0467 0.0869
Trichomonas vaginalis conserved hypothetical protein 0.0099 0.0836 0.1484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.045 0.0758
Onchocerca volvulus Cathepsin L homolog 0.0535 0.5374 1
Echinococcus granulosus lamin dm0 0.0033 0.0148 0.0175
Onchocerca volvulus 0.0099 0.0836 0.1317
Brugia malayi Cathepsin L-like precursor 0.0535 0.5374 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.1118 0.2081
Schistosoma mansoni hypothetical protein 0.0022 0.004 0.0047
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.045 0.053
Onchocerca volvulus 0.0358 0.3534 0.648
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0099 0.0836 0.1484
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0099 0.0836 0.1484
Onchocerca volvulus Huntingtin homolog 0.0148 0.1349 0.2298
Loa Loa (eye worm) hypothetical protein 0.0148 0.1349 0.251
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.045 0.053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Brugia malayi Bromodomain containing protein 0.0081 0.0647 0.1129
Plasmodium falciparum serine repeat antigen 3 0.0099 0.0836 0.1484
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0099 0.0836 0.1556
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0099 0.0836 0.1484
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1939 0.3553
Onchocerca volvulus 0.0535 0.5374 1
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0099 0.0836 0.1556
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0099 0.0836 0.1484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Trypanosoma cruzi cysteine peptidase, putative 0.0535 0.5374 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0535 0.5374 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0535 0.5374 1
Brugia malayi Papain family cysteine protease containing protein 0.0275 0.2676 0.4936
Schistosoma mansoni biogenic amine (5HT) receptor 0.0126 0.1118 0.1319
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0207 0.0303
Brugia malayi cathepsin Z-like cysteine proteinase 0.0099 0.0836 0.1484
Echinococcus multilocularis zinc finger protein 0.0021 0.0028 0.0028
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0099 0.0836 0.0986
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0476 0.0562
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0358 0.3534 0.6547
Trypanosoma brucei protein kinase, putative 0.0062 0.045 0.0758
Echinococcus granulosus cathepsin l cysteine peptidase 0.0535 0.5374 0.6336
Leishmania major cytochrome p450-like protein 0.0028 0.0098 0.0097
Leishmania major cathepsin L-like protease 0.0535 0.5374 1
Trypanosoma cruzi cysteine protease, putative 0.0275 0.2676 0.4936
Giardia lamblia Cathepsin L precursor 0.0099 0.0836 1
Echinococcus multilocularis cathepsin L 0.0099 0.0836 0.0836
Echinococcus granulosus cathepsin L cysteine proteinase 0.0535 0.5374 0.6336
Brugia malayi intermediate filament protein 0.0033 0.0148 0.0192
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0535 0.5374 1
Schistosoma mansoni cathepsin S (C01 family) 0.0099 0.0836 0.0986
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1939 0.3553
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0099 0.0836 0.1484
Giardia lamblia Cathepsin L-like protease 0.0099 0.0836 1
Brugia malayi MAP kinase sur-1 0.0062 0.045 0.0758
Entamoeba histolytica cysteine protease, putative 0.0099 0.0836 0.1484
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0099 0.0836 0.1484
Leishmania major cathepsin L-like protease 0.0535 0.5374 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0535 0.5374 0.5374
Giardia lamblia Cysteine protease 0.0099 0.0836 1
Giardia lamblia Cathepsin B precursor 0.0099 0.0836 1
Loa Loa (eye worm) hypothetical protein 0.0358 0.3534 0.6577
Plasmodium vivax serine-repeat antigen (SERA) 0.0099 0.0836 0.1484
Echinococcus granulosus cysteine protease 0.0275 0.2676 0.3155
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0007 0.0013
Echinococcus multilocularis cathepsin b 0.0099 0.0836 0.0836
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0207 0.0303
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0275 0.2676 0.4936
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Toxoplasma gondii cathepsin CPC1 0.0099 0.0836 0.1484
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.045 0.045
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0207 0.0207
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0099 0.0836 0.1484
Schistosoma mansoni cathepsin C 0.0099 0.0836 0.0986
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.3055 0.5685
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Loa Loa (eye worm) hypothetical protein 0.0126 0.1118 0.2081
Plasmodium falciparum serine repeat antigen 8 0.0099 0.0836 0.1484
Loa Loa (eye worm) hypothetical protein 0.0099 0.0836 0.1556
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0275 0.2676 0.3155
Entamoeba histolytica cysteine proteinase, putative 0.0535 0.5374 1
Trypanosoma cruzi cysteine peptidase, putative 0.0177 0.1649 0.3009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0099 0.0836 0.1484
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0099 0.0836 0.1484
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0836 0.0986
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0275 0.2676 0.3155
Schistosoma mansoni cathepsin F (C01 family) 0.0535 0.5374 0.6336
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0099 0.0836 0.1484
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.045 0.0758
Brugia malayi Cytochrome P450 family protein 0.0063 0.0467 0.079
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3055 0.5648
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0099 0.0836 0.1484
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0207 0.0303
Echinococcus granulosus cathepsin l1 0.0358 0.3534 0.4167
Giardia lamblia Cathepsin L precursor 0.0099 0.0836 1
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0098 0.0097
Leishmania major cathepsin L-like protease 0.0535 0.5374 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0836 0.0986
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.8482 0.8482
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0099 0.0836 0.1484
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Echinococcus multilocularis lamin dm0 0.0033 0.0148 0.0148
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.045 0.0758
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.045 0.0758
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0061 0.0061
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0046 0.0085
Loa Loa (eye worm) fibroinase 0.0535 0.5374 1
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.045 0.5111
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0099 0.0836 0.1484
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.045 0.0758
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0535 0.5374 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0836 0.0986
Trypanosoma cruzi cruzipain precursor, putative 0.0177 0.1649 0.3009
Toxoplasma gondii cathepsin CPC2 0.0099 0.0836 0.1484
Echinococcus granulosus cathepsin L 0.0275 0.2676 0.3155
Echinococcus granulosus lamin 0.0033 0.0148 0.0175
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0535 0.5374 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0211 0.0211
Onchocerca volvulus 0.0535 0.5374 1
Schistosoma mansoni lamin 0.0033 0.0148 0.0175
Plasmodium vivax vivapain-1 0.0275 0.2676 0.4936
Echinococcus multilocularis musashi 0.0033 0.0148 0.0148
Loa Loa (eye worm) hypothetical protein 0.0099 0.0836 0.1556
Plasmodium falciparum serine repeat antigen 5 0.0099 0.0836 0.1484
Plasmodium vivax serine-repeat antigen (SERA) 0.0099 0.0836 0.1484
Giardia lamblia Cathepsin L-like protease 0.0099 0.0836 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0836 0.0986
Brugia malayi cathepsin L precursor 0.0099 0.0836 0.1484
Giardia lamblia Cathepsin B precursor 0.0099 0.0836 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0207 0.0303
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0166 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0535 0.5374 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.045 0.0758
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0099 0.0836 0.1484
Leishmania major cathepsin L-like protease 0.0535 0.5374 1
Echinococcus granulosus cathepsin b 0.0099 0.0836 0.0986
Entamoeba histolytica cysteine protease, putative 0.0535 0.5374 1
Entamoeba histolytica cysteine protease, putative 0.0099 0.0836 0.1484
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0098 0.0181
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.0836 0.0986
Brugia malayi cathepsin L-like precursor 0.0358 0.3534 0.6547
Loa Loa (eye worm) hypothetical protein 0.0535 0.5374 1
Entamoeba histolytica cysteine protease, putative 0.0099 0.0836 0.1484
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.3055 0.5648
Echinococcus granulosus biogenic amine 5HT receptor 0.0126 0.1118 0.1319
Toxoplasma gondii cathepsin CPL 0.0535 0.5374 1
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0098 0.0097
Plasmodium falciparum cysteine proteinase falcipain 1 0.0275 0.2676 0.4936
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0099 0.0836 0.1484
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0148 0.0276
Brugia malayi fibroinase precursor 0.0099 0.0836 0.1484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0535 0.5374 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0535 0.5374 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0099 0.0836 0.0986
Echinococcus multilocularis cathepsin L cysteine protease 0.0535 0.5374 0.5374
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.045 0.0837
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.045 0.0758
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0374 0.3701 0.3701
Leishmania major cathepsin L-like protease 0.0535 0.5374 1
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0099 0.0836 0.1484
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0207 0.0303
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0099 0.0836 0.1484
Giardia lamblia Cathepsin B precursor 0.0099 0.0836 1
Brugia malayi Cathepsin L-like precursor 0.0177 0.1649 0.3009
Entamoeba histolytica cysteine protease, putative 0.0099 0.0836 0.1484
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0098 0.0181
Entamoeba histolytica cysteine protease, putative 0.0275 0.2676 0.4936
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0177 0.1649 0.3009
Plasmodium vivax unspecified product 0.0099 0.0836 0.1484
Plasmodium vivax vivapain-3 0.0275 0.2676 0.4936
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0275 0.2676 0.4936
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0099 0.0836 0.1484
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0535 0.5374 0.5374
Schistosoma mansoni bromodomain containing protein 0.0068 0.0516 0.0609
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0535 0.5374 1
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0099 0.0836 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0099 0.0836 0.1484
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0099 0.0836 0.1484
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0046 0.0046
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0358 0.3534 0.6547
Onchocerca volvulus 0.0535 0.5374 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.045 0.0758
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0046 0.0054
Onchocerca volvulus Cathepsin L homolog 0.0099 0.0836 0.1317
Brugia malayi Papain family cysteine protease containing protein 0.0099 0.0836 0.1484
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0207 1
Loa Loa (eye worm) hypothetical protein 0.0358 0.3534 0.6577
Trypanosoma cruzi cysteine proteinase, putative 0.0275 0.2676 0.4936
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0099 0.0836 0.1484
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0099 0.0836 0.1484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0358 0.3534 0.6547
Entamoeba histolytica cysteine proteinase 2 0.0275 0.2676 0.4936
Loa Loa (eye worm) ctsf protein 0.0535 0.5374 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0061 0.0072
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.1939 0.3553
Plasmodium vivax vivapain-2 0.0535 0.5374 1
Leishmania major cathepsin L-like protease 0.0535 0.5374 1
Giardia lamblia Cathepsin L precursor 0.0099 0.0836 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0061 0.0072
Entamoeba histolytica cysteine proteinase 1, putative 0.0275 0.2676 0.4936

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 1.258925412 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 6.309573445 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 6.309573445 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 6.309573445 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (functional) 0.0032 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.631 um PUBCHEM_BIOASSAY: qHTS Assay for Anthrax Lethal Toxin Internalization. (Class of assay: confirmatory) ChEMBL. No reference
Potency (ADMET) = 1.2589 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C19. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) 2.6169 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 4.6535 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (ADMET) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2D6. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9. (Class of assay: confirmatory) [Related pubchem assays: 885, 884, 410 ] ChEMBL. No reference
Potency (ADMET) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) 9.2 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF. (Class of assay: confirmatory) [Related pubchem assays: 995 ] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 17.7828 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 63.0957 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 112.2018 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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