Detailed information for compound 1449912

Basic information

Technical information
  • TDR Targets ID: 1449912
  • Name: 1-[2-[4-(4-fluorophenyl)piperazin-1-yl]-2-oxo ethyl]-8-methylchromeno[3,4-d]pyrazol-4-one
  • MW: 420.436 | Formula: C23H21FN4O3
  • H donors: 0 H acceptors: 3 LogP: 3.07 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)N1CCN(CC1)C(=O)Cn1ncc2c1c1cc(C)ccc1oc2=O
  • InChi: 1S/C23H21FN4O3/c1-15-2-7-20-18(12-15)22-19(23(30)31-20)13-25-28(22)14-21(29)27-10-8-26(9-11-27)17-5-3-16(24)4-6-17/h2-7,12-13H,8-11,14H2,1H3
  • InChiKey: BPBOZWFHFDLMHF-UHFFFAOYSA-N  

Network

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Synonyms

  • 1-[2-[4-(4-fluorophenyl)piperazin-1-yl]-2-oxo-ethyl]-8-methyl-chromeno[3,4-d]pyrazol-4-one
  • 1-[2-[4-(4-fluorophenyl)-1-piperazinyl]-2-oxoethyl]-8-methyl-4-chromeno[3,4-d]pyrazolone
  • 1-[2-[4-(4-fluorophenyl)piperazin-1-yl]-2-keto-ethyl]-8-methyl-chromeno[3,4-d]pyrazol-4-one
  • C618-0681
  • NCGC00110963-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Plasmodium falciparum glutathione reductase 0.0052 0.0188 0.2803
Echinococcus multilocularis dna polymerase kappa 0.014 0.0621 0.1438
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0046 0.0167
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0061 0.0338
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0027 0.0062 0.0226
Brugia malayi Cytochrome P450 family protein 0.0026 0.006 0.033
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0221
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0058 0.0215 0.3192
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0088 0.0364 0.3341
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0015 0.0034
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.205 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0383 0.3519
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0027 0.015
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0023 0.0035
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0061 0.056
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0006 0.0075
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0035 0.0103 0.0571
Giardia lamblia Cathepsin B precursor 0.0018 0.0023 0.0431
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0015 0.0034
Loa Loa (eye worm) helicase 0.0035 0.0103 0.0571
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0181 0.0283
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0027 0.0063
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0052 0.0188 0.2504
Loa Loa (eye worm) hypothetical protein 0.0098 0.0412 0.2276
Schistosoma mansoni smad1 5 8 and 0.0026 0.006 0.0139
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0027 0.0062 0.0929
Entamoeba histolytica hypothetical protein 0.0151 0.0673 1
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0023 0.0124
Giardia lamblia Hypothetical protein 0.0018 0.0023 0.0431
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0873
Echinococcus granulosus Ankyrin 0.0014 0.0003 0.0007
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0061 0.0338
Brugia malayi MH1 domain containing protein 0.0014 0.0003 0.0016
Entamoeba histolytica cysteine proteinase, putative 0.004 0.013 0.1938
Plasmodium falciparum cysteine proteinase falcipain 1 0.004 0.013 0.1948
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0088 0.0364 0.5408
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0006 0.0013
Entamoeba histolytica hypothetical protein 0.0151 0.0673 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0022 0.0331
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0976
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.013 0.174
Trypanosoma cruzi DNA polymerase kappa, putative 0.014 0.0621 0.0972
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0151 0.2017
Trypanosoma brucei DNA polymerase eta, putative 0.0166 0.0749 1
Entamoeba histolytica hypothetical protein 0.0023 0.0046 0.0686
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0114 0.0491 0.2712
Trypanosoma brucei DNA polymerase IV, putative 0.014 0.0621 0.8281
Onchocerca volvulus 0.0056 0.021 0.1922
Schistosoma mansoni polycystin 1-related 0.002 0.0028 0.0066
Echinococcus multilocularis tar DNA binding protein 0.007 0.0277 0.0643
Brugia malayi Protein cec-1. 0.0035 0.0103 0.0571
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0052 0.0188 0.0294
Loa Loa (eye worm) hypothetical protein 0.0122 0.0529 0.2923
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0124
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.1926 0.4463
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0094 0.0395 0.1426
Onchocerca volvulus 0.0027 0.0064 0.0583
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0061 0.0338
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0057 0.0213 0.0297
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Leishmania major DNA polymerase eta, putative 0.0088 0.0364 0.4858
Trypanosoma brucei calcium-transporting ATPase, putative 0.004 0.013 0.1737
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.1085 0.2514
Schistosoma mansoni cation-transporting ATPase 0.0027 0.0062 0.0145
Loa Loa (eye worm) hypothetical protein 0.0014 0.0002 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0461
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.021 0.3114
Trypanosoma cruzi cruzipain precursor, putative 0.1314 0.6384 1
Trypanosoma brucei P-type H+-ATPase, putative 0.0054 0.0195 0.2601
Plasmodium vivax thioredoxin reductase, putative 0.015 0.0669 1
Treponema pallidum NADH oxidase 0.0052 0.0188 0.0188
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.0523 0.6981
Loa Loa (eye worm) hypothetical protein 0.0063 0.0242 0.1339
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0114 0.0491 0.1138
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0023 0.0052
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0107 0.0167
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0111 0.0615
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0188 0.0294
Brugia malayi MH1 domain containing protein 0.0026 0.006 0.0332
Mycobacterium ulcerans DNA polymerase IV 0.014 0.0621 0.0621
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.006 0.0139
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0023 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0212 0.1949
Schistosoma mansoni hypothetical protein 0.0035 0.0103 0.0239
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0084 0.0345 0.0345
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0252 0.0584
Schistosoma mansoni transcription factor LCR-F1 0.0151 0.0673 0.156
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0138 0.032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0873
Plasmodium falciparum serine repeat antigen 6 0.0018 0.0023 0.0337
Brugia malayi E1-E2 ATPase family protein 0.0027 0.0062 0.0345
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0003 0.0014
Onchocerca volvulus 0.0236 0.109 1
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0103 0.1543
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0108 0.0995
Onchocerca volvulus 0.0056 0.021 0.1922
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0207
Echinococcus multilocularis Chromobox protein 3 0.0035 0.0103 0.0239
Giardia lamblia Cysteine protease 0.0018 0.0023 0.0431
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0094 0.0395 0.5272
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0023 0.0124
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0431 0.1
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0027 0.0062 0.0062
Entamoeba histolytica cysteine proteinase, putative 0.004 0.013 0.1938
Loa Loa (eye worm) transcription factor SMAD2 0.0382 0.181 1
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0057 0.0213 0.0213
Echinococcus granulosus tumor protein p63 0.0335 0.1579 0.3659
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0111 0.0258
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0207
Trypanosoma cruzi major cysteine proteinase, putative 0.0112 0.0481 0.0754
Echinococcus granulosus dna polymerase kappa 0.014 0.0621 0.1438
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.0621 0.8281
Schistosoma mansoni hypothetical protein 0.0017 0.0018 0.0042
Giardia lamblia Cathepsin B precursor 0.0018 0.0023 0.0431
Loa Loa (eye worm) hypothetical protein 0.0051 0.018 0.0996
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0111 0.0258
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0052 0.0188 0.2504
Loa Loa (eye worm) hypothetical protein 0.0047 0.0163 0.0898
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0088 0.0366 0.336
Loa Loa (eye worm) RecQ helicase 0.0047 0.0162 0.0897
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.013 0.174
Brugia malayi MAP kinase sur-1 0.0051 0.0181 0.0997
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.013 0.1197
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0018 0.0023 0.0337
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0052 0.0188 0.1037
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0018 0.0023 0.0337
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0088 0.0364 0.5408
Schistosoma mansoni cpg binding protein 0.0029 0.0072 0.0167
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0077 0.0313 0.0725
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0108 0.161
Trichomonas vaginalis conserved hypothetical protein 0.0092 0.0383 0.3519
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0027 0.0062 0.0226
Loa Loa (eye worm) cathepsin B 0.0018 0.0023 0.0124
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0009 0.0125
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.004 0.013 0.0204
Onchocerca volvulus 0.0035 0.0102 0.0933
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0023 0.0337
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0103 0.0948
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0107 0.1422
Echinococcus granulosus chromobox protein 1 0.0155 0.0694 0.1608
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0015 0.0023
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0046 0.0616
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.021 0.0486
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.013 0.1197
Echinococcus granulosus cathepsin l cysteine peptidase 0.0056 0.021 0.0486
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.006 0.0332
Loa Loa (eye worm) hypothetical protein 0.0315 0.1478 0.8165
Onchocerca volvulus 0.0065 0.0252 0.231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0128 0.056 0.0878
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0023 0.0309
Echinococcus multilocularis chromobox protein 2 0.0035 0.0103 0.0239
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Echinococcus granulosus cation transporting ATPase 13A1 0.0027 0.0062 0.0145
Loa Loa (eye worm) calcium ATPase 0.0058 0.0215 0.1187
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.035 0.4667
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0106 0.0165
Echinococcus granulosus cation transporting ATPase 13A3 0.0027 0.0062 0.0145
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0002 0.0005
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0006 0.0009
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0108 0.0995
Loa Loa (eye worm) hypothetical protein 0.0042 0.0138 0.0763
Echinococcus granulosus smad 0.0026 0.006 0.0139
Echinococcus granulosus phospholipid transporting ATPase VA 0.0017 0.0015 0.0034
Brugia malayi hypothetical protein 0.002 0.0028 0.0156
Echinococcus multilocularis cpg binding protein 0.003 0.008 0.0186
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0048 0.0112
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0002 0.0005
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0002 0.0005
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0018 0.0023 0.0337
Schistosoma mansoni smad 0.0026 0.006 0.0139
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0114 0.0491 0.1138
Loa Loa (eye worm) TAR-binding protein 0.007 0.0277 0.1532
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0135 0.1239
Echinococcus granulosus cathepsin b 0.0018 0.0023 0.0052
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0035 0.0103 0.1543
Schistosoma mansoni terminal deoxycytidyl transferase 0.0114 0.0491 0.1138
Giardia lamblia Cathepsin B precursor 0.0018 0.0023 0.0431
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0027 0.0062 0.0062
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.007 0.0277 0.1532
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0578 0.277 0.277
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0265 0.0614
Trypanosoma cruzi DNA polymerase eta, putative 0.0088 0.0364 0.057
Toxoplasma gondii exonuclease III APE 0.0018 0.0022 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0074 0.0682
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0018 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0207
Giardia lamblia DINP protein human, muc B family 0.012 0.0523 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0108 0.161
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0088 0.0364 0.5408
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0103 0.0948
Schistosoma mansoni lipoxygenase 0.002 0.0028 0.0066
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0027 0.015
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0119 0.1094
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0055 0.0506
Giardia lamblia Cathepsin L-like protease 0.0018 0.0023 0.0431
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0015 0.0034
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0002 0.0012
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0342 0.1614 0.2254
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0094 0.0395 0.0916
Plasmodium falciparum glutathione reductase 0.015 0.0669 1
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0181 0.0418
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0063 0.0579
Trichomonas vaginalis cation-transporting ATPase, putative 0.0119 0.0518 0.4756
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Trichomonas vaginalis C-MYB, putative 0.0088 0.0364 0.3341
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.1085 0.2514
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0335
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0027 0.0063
Schistosoma mansoni hypothetical protein 0.004 0.0131 0.0303
Schistosoma mansoni chromobox protein 0.0155 0.0694 0.1608
Plasmodium falciparum serine repeat antigen 1 0.0018 0.0023 0.0337
Brugia malayi Uncoordinated protein 44 0.0014 0.0002 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0461
Trypanosoma brucei glucosidase, putative 0.0036 0.0108 0.1446
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.006 0.033
Mycobacterium ulcerans DNA polymerase IV 0.014 0.0621 0.0621
Giardia lamblia NADH oxidase lateral transfer candidate 0.0052 0.0188 0.3587
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0027 0.0062 0.0062
Brugia malayi Papain family cysteine protease containing protein 0.004 0.013 0.0721
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0207
Brugia malayi Cathepsin L-like precursor 0.0056 0.021 0.1158
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0009 0.0015
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0027 0.0062 0.0098
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0027 0.0062 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0135 0.1239
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0023 0.0207
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.205 1 1
Echinococcus multilocularis Ankyrin 0.0014 0.0003 0.0007
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0023 0.0124
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.021 0.1923
Treponema pallidum hypothetical protein 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0062 0.0345
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0578 0.277 0.3868
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0124
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0151 0.035
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0027 0.0062 0.0087
Onchocerca volvulus Cathepsin L homolog 0.0056 0.021 0.1922
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0052 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0056 0.021 0.1158
Loa Loa (eye worm) hypothetical protein 0.0055 0.0204 0.1125
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0203 0.0732
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0027 0.0062 0.0929
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0103 0.0436 0.101
Trypanosoma cruzi DNA polymerase eta, putative 0.0166 0.0749 0.1174
Plasmodium vivax DNA repair protein REV1, putative 0.0035 0.0106 0.1578
Schistosoma mansoni hypothetical protein 0.004 0.0131 0.0303
Schistosoma mansoni smad1 5 8 and 0.0026 0.006 0.0139
Mycobacterium tuberculosis Probable dehydrogenase 0.0342 0.1614 0.2254
Echinococcus multilocularis cathepsin b 0.0018 0.0023 0.0052
Schistosoma mansoni hypothetical protein 0.002 0.0028 0.0066
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0124
Trypanosoma cruzi DNA polymerase kappa, putative 0.014 0.0621 0.0972
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0086 0.031
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0108 0.1446
Loa Loa (eye worm) hypothetical protein 0.0166 0.0749 0.414
Giardia lamblia Myb 1-like protein 0.0088 0.0366 0.6995
Onchocerca volvulus 0.002 0.0028 0.0259
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0114 0.0264
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0006 0.0075
Echinococcus granulosus bloom syndrome protein 0.0047 0.0162 0.0376
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0028 0.0422
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0061 0.056
Toxoplasma gondii cathepsin CPC2 0.0018 0.0023 0.0081
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0151 0.0835
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0088 0.0364 0.5408
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0106 0.1409
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0181 0.1657
Schistosoma mansoni chromobox protein 0.0155 0.0694 0.1608
Entamoeba histolytica hypothetical protein 0.0035 0.0103 0.1535
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0103 0.0948
Loa Loa (eye worm) hypothetical protein 0.0035 0.0102 0.0562
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0022 0.0423
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0098 0.0413 0.3792
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0077 0.0313 0.0725
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.0621 0.8281
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0023 0.0052
Loa Loa (eye worm) hypothetical protein 0.0092 0.0383 0.2118
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0027 0.0062 0.0834
Trichomonas vaginalis MYB3r3, putative 0.0088 0.0364 0.3341
Schistosoma mansoni tar DNA-binding protein 0.007 0.0277 0.0643
Giardia lamblia Cathepsin L precursor 0.0018 0.0023 0.0431
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0057 0.0213 0.0297
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0009 0.0009
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0108 0.0251
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0102 0.0431 0.1
Onchocerca volvulus Peroxidase homolog 0.0026 0.0061 0.056
Brugia malayi ImpB/MucB/SamB family protein 0.0166 0.0749 0.414
Loa Loa (eye worm) nuclear factor I 0.0014 0.0003 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0207
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0052 0.0188 0.0188
Trypanosoma brucei calcium-translocating P-type ATPase 0.0103 0.0436 0.5814
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0207
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0094 0.0395 0.5871
Giardia lamblia Hypothetical protein 0.0018 0.0023 0.0431
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.021 0.1923
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0181 0.0283
Trypanosoma cruzi P-type H+-ATPase, putative 0.0037 0.0112 0.0176
Plasmodium vivax unspecified product 0.004 0.013 0.1948
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.0621 0.8281
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0103 0.0239
Leishmania major cathepsin L-like protease 0.015 0.0668 0.8915
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0094 0.0395 0.5272
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.4025 0.9327
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Plasmodium falciparum thioredoxin reductase 0.0052 0.0188 0.2803
Schistosoma mansoni copper ABC transporter ATPase 0.0027 0.0062 0.0145
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0023 0.0124
Schistosoma mansoni hypothetical protein 0.0406 0.1926 0.4463
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0027 0.0062 0.0145
Leishmania major cathepsin L-like protease 0.0056 0.021 0.2796
Brugia malayi Cathepsin L-like precursor 0.0056 0.021 0.1158
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0151 0.2246
Onchocerca volvulus Peroxidase homolog 0.0026 0.0061 0.056
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0335
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.013 0.0302
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0381 0.1802 0.2516
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0052 0.0188 0.2504
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0081 0.0291
Loa Loa (eye worm) E1-E2 ATPase 0.0054 0.0195 0.1077
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0204 0.1125
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0102 0.0236
Schistosoma mansoni DNA polymerase IV / kappa 0.0035 0.0106 0.0245
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0055 0.082
Loa Loa (eye worm) hypothetical protein 0.0146 0.065 0.3593
Schistosoma mansoni DNA polymerase eta 0.0166 0.0749 0.1737
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0089 0.037 0.0858
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0023 0.0124
Onchocerca volvulus Huntingtin homolog 0.0122 0.0529 0.4854
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0578 0.277 1
Brugia malayi intermediate filament protein 0.0027 0.0064 0.0351
Leishmania major trypanothione reductase 0.015 0.0669 0.8933
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.037 0.0858
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0094 0.0395 0.7552
Leishmania major cytochrome p450-like protein 0.0016 0.0009 0.0125
Onchocerca volvulus 0.0056 0.021 0.1922
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.004 0.0221
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0022 0.0031
Echinococcus granulosus neuropeptide receptor A26 0.0465 0.2217 0.5137
Plasmodium vivax calcium-transporting ATPase, putative 0.0119 0.0518 0.774
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0055 0.0736
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0028 0.0066
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0052 0.0188 0.0435
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0023 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0103 0.0948
Loa Loa (eye worm) hypothetical protein 0.003 0.0081 0.0446
Entamoeba histolytica hypothetical protein 0.0151 0.0673 1
Brugia malayi hypothetical protein 0.0026 0.0061 0.0338
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0463
Echinococcus multilocularis GPCR, family 2 0.0017 0.0018 0.0042
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0064 0.0351
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0027 0.0063
Echinococcus multilocularis Chromo domain 0.0035 0.0103 0.0239
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0188 0.0294
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0094 0.0395 0.0916
Brugia malayi Pre-SET motif family protein 0.003 0.0081 0.0446
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0064 0.0351
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0072 0.0399
Schistosoma mansoni peroxidasin 0.0026 0.0061 0.0142
Trichomonas vaginalis Heterochromatin protein, putative 0.0035 0.0103 0.0948
Toxoplasma gondii melibiase subfamily protein 0.0102 0.0431 0.1557
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0108 0.017
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0018 0.01
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0335
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0027 0.0062 0.0345
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.006 0.0139
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0023 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0181 0.0418
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.0618 0.1432
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0181 0.0283
Schistosoma mansoni tar DNA-binding protein 0.007 0.0277 0.0643
Trypanosoma brucei cation-transporting ATPase, putative 0.0027 0.0062 0.0834
Echinococcus granulosus chromobox protein 1 0.0155 0.0694 0.1608
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0084 0.0345 0.5127
Echinococcus granulosus expressed conserved protein 0.0092 0.0383 0.0887
Schistosoma mansoni hypothetical protein 0.0017 0.0018 0.0042
Trichomonas vaginalis cation-transporting ATPase, putative 0.0119 0.0518 0.4756
Brugia malayi MH1 domain containing protein 0.0014 0.0003 0.0016
Echinococcus granulosus GPCR family 2 0.0017 0.0018 0.0042
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0047 0.0163 0.2415
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Brugia malayi CHD4 protein 0.0036 0.0111 0.0615
Brugia malayi RNA recognition motif domain containing protein 0.007 0.0277 0.1532
Brugia malayi Cathepsin L-like precursor 0.0056 0.021 0.1158
Giardia lamblia DNA damage repair protein 0.0035 0.0106 0.2019
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0181 0.1657
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.013 0.0302
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0103 0.0436 0.101
Giardia lamblia Cathepsin L precursor 0.0018 0.0023 0.0431
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0135 0.1239
Schistosoma mansoni hypothetical protein 0.0892 0.4315 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0181 0.0283
Leishmania major calcium-translocating P-type ATPase 0.0119 0.0518 0.6914
Entamoeba histolytica hypothetical protein 0.0035 0.0103 0.1535
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0037 0.0112 0.0406
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0067 0.0263 0.0411
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0068 0.0265 0.2432
Trichomonas vaginalis chromobox protein, putative 0.0155 0.0694 0.6366
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0006 0.0031
Loa Loa (eye worm) heterochromatin protein 1 0.0155 0.0694 0.3831
Brugia malayi cathepsin L precursor 0.0018 0.0023 0.0124
Brugia malayi polk-prov protein 0.0062 0.0235 0.1299
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0023 0.0207
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0015 0.0053
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0009 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0191 0.2854
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0027 0.0062 0.0145
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.021 0.1923
Echinococcus granulosus calcium transporting atpase 0.0103 0.0436 0.101
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0103 0.0436 0.101
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0221
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0337 0.1864
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0103 0.0239
Trichomonas vaginalis C-MYB, putative 0.0088 0.0364 0.3341
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0094 0.0395 0.0619
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1472 0.7162 1
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0035 0.0105 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0463
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.021 0.0486
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0023 0.0301
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0015 0.0034
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0023 0.0124
Onchocerca volvulus Huntingtin homolog 0.0122 0.0529 0.4854
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.021 0.1923
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0156
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0056 0.021 0.313
Trichomonas vaginalis set domain proteins, putative 0.0236 0.109 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0235 0.3139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Leishmania major P-type H -ATPase, putative 0.0054 0.0195 0.2601
Onchocerca volvulus Cathepsin L homolog 0.0056 0.021 0.1922
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.0726 0.1683
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0191 0.069
Giardia lamblia Cathepsin B precursor 0.0018 0.0023 0.0431
Giardia lamblia Cysteine protease 0.0018 0.0023 0.0431
Trichomonas vaginalis hypothetical protein 0.0035 0.0103 0.0948
Brugia malayi Cathepsin L-like precursor 0.0056 0.021 0.1158
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0027 0.0407
Schistosoma mansoni ap endonuclease 0.0018 0.0022 0.0051
Brugia malayi hypothetical protein 0.0151 0.0673 0.3718
Giardia lamblia Cysteine protease 0.0018 0.0023 0.0431
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0114 0.0491 0.1138
Brugia malayi CXXC zinc finger family protein 0.0029 0.0072 0.0399
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.0412 0.2276
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0046 0.0689
Loa Loa (eye worm) hypothetical protein 0.0084 0.0345 0.1906
Loa Loa (eye worm) hypothetical protein 0.0027 0.0064 0.0351
Loa Loa (eye worm) hypothetical protein 0.0051 0.0184 0.1019
Loa Loa (eye worm) hypothetical protein 0.0035 0.0103 0.0571
Schistosoma mansoni hypothetical protein 0.0017 0.0018 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0108 0.017
Echinococcus granulosus Chromobox protein 3 0.0035 0.0103 0.0239
Trypanosoma cruzi DNA polymerase kappa, putative 0.014 0.0621 0.0972
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0023 0.0207
Echinococcus multilocularis cathepsin L 0.004 0.013 0.0302
Brugia malayi MH1 domain containing protein 0.0026 0.006 0.0332
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0976
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0009 0.0052
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0067 0.0263 0.502
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0052 0.0188 0.2803
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0162 0.0897
Schistosoma mansoni survival motor neuron protein 0.0048 0.0167 0.0388
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0081 0.0187
Echinococcus granulosus chromobox protein 2 0.0035 0.0103 0.0239
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0027 0.0062 0.0098
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0151 0.0835
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0023 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0463
Schistosoma mansoni tar DNA-binding protein 0.007 0.0277 0.0643
Brugia malayi Protein kinase domain containing protein 0.0015 0.0004 0.0025
Giardia lamblia Cathepsin B precursor 0.0018 0.0023 0.0431
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0027 0.0062 0.0929
Brugia malayi Melibiase family protein 0.0068 0.0265 0.1464
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0023 0.0335
Echinococcus granulosus death domain containing protein 0.0014 0.0002 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0463
Echinococcus granulosus dnaJ subfamily B 0.0406 0.1926 0.4463
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0151 0.2017
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.0621 0.8281
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0022 0.0022
Leishmania major cathepsin L-like protease 0.0056 0.021 0.2796
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0023 0.0052
Giardia lamblia Cathepsin L precursor 0.0018 0.0023 0.0431
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0119 0.0518 0.0518
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0017 0.0015 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0081 0.0187
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0018 0.0023 0.0337
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0018 0.0023 0.0337
Toxoplasma gondii Alpha-galactosidase 0.0014 0.0003 0.001
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0023 0.0081
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0088 0.0364 0.3341
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0056 0.021 0.1158
Loa Loa (eye worm) thioredoxin reductase 0.015 0.0669 0.3698
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0006 0.0052
Plasmodium falciparum serine repeat antigen 2 0.0018 0.0023 0.0337
Brugia malayi MH2 domain containing protein 0.0026 0.006 0.0332
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0006 0.0009
Brugia malayi Cathepsin L-like precursor 0.0056 0.021 0.1158
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0103 0.1535
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0018 0.0023 0.0337
Onchocerca volvulus 0.0056 0.021 0.1922
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0151 0.035
Echinococcus granulosus X box binding protein 1 0.0286 0.1336 0.3097
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0108 0.0251
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0022 0.0022
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0027 0.0062 0.0574
Echinococcus multilocularis thioredoxin glutathione reductase 0.015 0.0669 0.1552
Schistosoma mansoni ATPase 0.0119 0.0518 0.1201
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0023 0.0052
Plasmodium falciparum copper-transporting ATPase 0.0027 0.0062 0.0934
Plasmodium falciparum serine repeat antigen 8 0.0018 0.0023 0.0337
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0052 0.0188 0.2504
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.021 0.1923
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0023 0.0124
Onchocerca volvulus 0.0084 0.0345 0.3165
Brugia malayi Doublecortin family protein 0.002 0.0028 0.0156
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0018 0.0023 0.0337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0873
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0181 0.2409
Entamoeba histolytica cysteine proteinase 2 0.004 0.013 0.1938
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.021 0.0486
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0052 0.0188 0.0677
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0003 0.0014
Echinococcus granulosus copper transporting ATPase 1 0.0027 0.0062 0.0145
Leishmania major cysteine peptidase A (CPA) 0.0056 0.021 0.2796
Brugia malayi Cathepsin L-like precursor 0.0035 0.0102 0.0562
Leishmania major calcium motive p-type ATPase, putative 0.0067 0.0263 0.3504
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0037 0.0112 0.0621
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0342 0.1614 0.2254
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0111 0.0258
Schistosoma mansoni tar DNA-binding protein 0.007 0.0277 0.0643
Trypanosoma brucei unspecified product 0.0134 0.0588 0.7852
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0006 0.0075
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0023 0.0124
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0022 0.0035
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0027 0.0062 0.0087
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0067 0.0263 0.0411
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0191 0.2854
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0023 0.0052
Trichomonas vaginalis chromobox protein, putative 0.0098 0.0413 0.3795
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0342 0.1614 0.2254
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0221
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0028 0.0422
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0036 0.0477
Echinococcus granulosus thioredoxin glutathione reductase 0.015 0.0669 0.1552
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.021 0.3114
Echinococcus granulosus tar DNA binding protein 0.007 0.0277 0.0643
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0094 0.0395 0.0619
Trichomonas vaginalis pc-MYB2, putative 0.0088 0.0364 0.3341
Schistosoma mansoni Smad4 0.0026 0.006 0.0139
Schistosoma mansoni chromobox protein 0.0035 0.0103 0.0239
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0076 0.0303 0.1675
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0181 0.0418
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0191 0.255
Brugia malayi RNA binding protein 0.007 0.0277 0.1532
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0052 0.0188 0.2504
Loa Loa (eye worm) ctsf protein 0.0056 0.021 0.1158
Echinococcus multilocularis cathepsin L 0.0018 0.0023 0.0052
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0023 0.0052
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.015 0.0669 0.0935
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.095 0.5245
Treponema pallidum cation-transporting ATPase, P-type 0.0027 0.0062 0.0062
Schistosoma mansoni ATPase 0.0119 0.0518 0.1201
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0022 0.0203
Schistosoma mansoni hypothetical protein 0.0051 0.0184 0.0427
Echinococcus granulosus cathepsin L 0.004 0.013 0.0302
Giardia lamblia Copper-transporting P-type ATPase 0.0027 0.0062 0.1195
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.0621 0.8281
Brugia malayi Smad1 0.0026 0.006 0.0332
Leishmania major cathepsin L-like protease 0.0056 0.021 0.2796
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.021 0.0486
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Loa Loa (eye worm) Smad1 0.0026 0.006 0.0332
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0023 0.0301
Schistosoma mansoni hypothetical protein 0.0151 0.0673 0.156
Schistosoma mansoni loxhd1 0.002 0.0028 0.0066
Schistosoma mansoni cpg binding protein 0.003 0.008 0.0186
Trypanosoma brucei DNA polymerase IV, putative 0.014 0.0621 0.8281
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0079 0.0726
Onchocerca volvulus 0.002 0.0028 0.0259
Loa Loa (eye worm) glutathione reductase 0.015 0.0669 0.3698
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.012 0.0523 0.0731
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0061 0.0338
Schistosoma mansoni lamin 0.0027 0.0064 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Schistosoma mansoni tar DNA-binding protein 0.007 0.0277 0.0643
Plasmodium vivax vivapain-3 0.004 0.013 0.1948
Schistosoma mansoni chromobox protein 0.0035 0.0103 0.0239
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0578 0.277 0.277
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0151 0.0673 0.156
Echinococcus multilocularis neuropeptide receptor A26 0.0465 0.2217 0.5137
Loa Loa (eye worm) hypothetical protein 0.0062 0.0238 0.1313
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0047 0.0165 0.091
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0077 0.0313 0.287
Echinococcus multilocularis musashi 0.0027 0.0064 0.0147
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0103 0.1543
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0038 0.012 0.0662
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0052 0.0188 0.2803
Plasmodium vivax SET domain protein, putative 0.003 0.0081 0.1206
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.0621 0.8281
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0207
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Entamoeba histolytica cysteine proteinase, putative 0.004 0.013 0.1938
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0023 0.0052
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0061 0.0338
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0094 0.0395 0.5272
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0103 0.0948
Brugia malayi Pre-SET motif family protein 0.0207 0.095 0.5245
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0064 0.0351
Loa Loa (eye worm) hypothetical protein 0.0035 0.0103 0.0571
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0119 0.0518 0.1201
Brugia malayi Valyl-tRNA synthetase 0.0035 0.0103 0.0571
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0023 0.0431
Echinococcus multilocularis cation transporting ATPase 13A1 0.0027 0.0062 0.0145
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0027 0.0062 0.0574
Onchocerca volvulus 0.0056 0.021 0.1922
Loa Loa (eye worm) hypothetical protein 0.0019 0.0027 0.015
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0056 0.021 0.313
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0046 0.0616
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0124
Entamoeba histolytica deoxycytidyl transferase, putative 0.0114 0.0491 0.7296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0873
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0023 0.0431
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0151 0.035
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0027 0.0062 0.0574
Loa Loa (eye worm) hypothetical protein 0.0035 0.0103 0.0571
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0006 0.0052
Plasmodium vivax vivapain-2 0.0056 0.021 0.313
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0028 0.0066
Echinococcus granulosus cathepsin l1 0.0035 0.0102 0.0236
Onchocerca volvulus 0.0056 0.021 0.1922
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.006 0.0139
Plasmodium vivax heterochromatin protein 1, putative 0.0035 0.0103 0.1543
Brugia malayi ImpB/MucB/SamB family protein 0.0114 0.0491 0.2712
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0063 0.0579
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0151 0.1388
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.0621 0.8281
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0022 0.0122
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0027 0.0062 0.0087
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.0412 0.0955
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0023 0.0052
Schistosoma mansoni hypothetical protein 0.004 0.0131 0.0303
Leishmania major copper-transporting ATPase-like protein, putative 0.0027 0.0062 0.0834
Echinococcus multilocularis chromobox protein 1 0.0155 0.0694 0.1608
Echinococcus multilocularis lamin dm0 0.0027 0.0064 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Trypanosoma cruzi copper-transporting ATPase, putative 0.0017 0.0015 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0023 0.0207
Schistosoma mansoni hypothetical protein 0.0017 0.0018 0.0042
Schistosoma mansoni hypothetical protein 0.0286 0.1336 0.3097
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0151 0.0237
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0023 0.0207
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0046 0.0046
Brugia malayi TAR-binding protein 0.007 0.0277 0.1532
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0023 0.0207
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0035 0.0103 0.0239
Plasmodium falciparum serine repeat antigen 5 0.0018 0.0023 0.0337
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0052 0.0188 0.0188
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0431 0.1
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0094 0.0395 0.5871
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0028 0.0066
Leishmania major proton motive ATPase, putative 0.0027 0.0062 0.0834
Brugia malayi chromobox protein homolog 3 0.0092 0.0383 0.2118
Brugia malayi hypothetical protein 0.0121 0.0525 0.2902
Brugia malayi hypothetical protein 0.0034 0.0099 0.0549
Echinococcus granulosus cysteine protease 0.004 0.013 0.0302
Schistosoma mansoni smad1 5 8 and 0.0026 0.006 0.0139
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0431 0.1
Echinococcus multilocularis smad 0.0026 0.006 0.0139
Plasmodium falciparum serine repeat antigen 9 0.0018 0.0023 0.0337
Echinococcus granulosus lamin 0.0027 0.0064 0.0147
Giardia lamblia Cysteine protease 0.0018 0.0023 0.0431
Trypanosoma cruzi calcium-transporting ATPase, putative 0.004 0.013 0.0204
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0018 0.0042
Schistosoma mansoni alpha glucosidase 0.0036 0.0108 0.0251
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0052 0.0188 0.0188
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0027 0.0063
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0088 0.0364 0.5408
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0023 0.0124
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0052 0.0188 0.2504
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0668 0.1047
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0023 0.0035
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0119 0.0518 0.1201
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0027 0.0062 0.0087
Plasmodium vivax unspecified product 0.0022 0.004 0.0599
Onchocerca volvulus 0.0094 0.0391 0.359
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0027 0.0098
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0002 0.0021
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0006 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0207
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.006 0.0332
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.021 0.1923
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0046 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0103 0.0948
Giardia lamblia Cathepsin B precursor 0.0018 0.0023 0.0431
Brugia malayi Cathepsin L-like precursor 0.0035 0.0102 0.0562
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0167 0.0924
Trichomonas vaginalis chromobox protein, putative 0.0155 0.0694 0.6366
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0124
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0046 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0976
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0357
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0108 0.0995
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0102 0.0933
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0151 0.2246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0151 0.1388
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0108 0.0995
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0023 0.0335
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0106 0.0165
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0003 0.0007
Plasmodium vivax P-type ATPase4, putative 0.0119 0.0518 0.774
Plasmodium falciparum serine repeat antigen 7 0.0018 0.0023 0.0337
Leishmania major cathepsin L-like protease 0.015 0.0668 0.8915
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0204 0.1125
Echinococcus granulosus cathepsin l1 0.0056 0.021 0.0486
Toxoplasma gondii NADPH-glutathione reductase 0.0052 0.0188 0.0677
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Echinococcus multilocularis geminin 0.0892 0.4315 1
Echinococcus granulosus cpg binding protein 0.003 0.008 0.0186
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Echinococcus granulosus cathepsin b 0.0018 0.0023 0.0052
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0027 0.0062 0.0145
Trichomonas vaginalis pc-MYB2, putative 0.0088 0.0364 0.3341
Brugia malayi CHE-14 protein 0.0042 0.0138 0.0763
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0002 0.0005
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.006 0.0139
Brugia malayi calcium ATPase 0.0037 0.0112 0.0621
Brugia malayi Cathepsin L-like precursor 0.0056 0.021 0.1158
Plasmodium vivax unspecified product 0.0018 0.0023 0.0337
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.0618 0.1432
Entamoeba histolytica cysteine proteinase 1, putative 0.004 0.013 0.1938
Echinococcus multilocularis protein patched 0.0042 0.0138 0.032
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0018 0.01
Onchocerca volvulus Cathepsin F homolog 0.0056 0.021 0.1922
Schistosoma mansoni patched 1 0.0042 0.0138 0.032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0102 0.0933
Brugia malayi Thioredoxin reductase 0.015 0.0669 0.3698
Schistosoma mansoni hypothetical protein 0.0892 0.4315 1
Schistosoma mansoni hypothetical protein 0.004 0.0131 0.0303
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0077 0.0313 0.0725
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.035 0.4667
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0023 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Trypanosoma cruzi P-type H+-ATPase, putative 0.0054 0.0195 0.0305
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.013 0.0302
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0102 0.0431 0.1
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0181 0.0418
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0062 0.0567
Brugia malayi Papain family cysteine protease containing protein 0.004 0.013 0.0721
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0052 0.0188 0.0435
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0052 0.0188 0.0294
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0088 0.0366 0.1321
Plasmodium falciparum heterochromatin protein 1 0.0035 0.0103 0.1543
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0151 0.2017
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0042 0.0138 0.0497
Loa Loa (eye worm) hypothetical protein 0.002 0.0028 0.0156
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0094 0.0395 0.3626
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0023 0.0337
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0188 0.0294
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0094 0.0395 0.3626
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0138 0.0763
Echinococcus granulosus lamin dm0 0.0027 0.0064 0.0147
Leishmania major DNA polymerase eta, putative 0.0166 0.0749 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0022 0.0331
Mycobacterium ulcerans hypothetical protein 0.0035 0.0106 0.0106
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0381 0.1802 0.2516
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Mycobacterium tuberculosis Probable oxidoreductase 0.0381 0.1802 0.2516
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0027 0.0062 0.0062
Brugia malayi Blistered cuticle protein 3 0.0026 0.0061 0.0338
Trypanosoma cruzi proton motive ATPase 1, putative 0.0017 0.0015 0.0023
Echinococcus multilocularis peroxidasin 0.0026 0.0061 0.0142
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0103 0.0436 0.2407
Echinococcus multilocularis tumor protein p63 0.0335 0.1579 0.3659
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.021 0.1923
Onchocerca volvulus 0.0026 0.0061 0.056
Schistosoma mansoni cathepsin C 0.0018 0.0023 0.0052
Leishmania major P-type ATPase, putative 0.0077 0.0313 0.4172
Trypanosoma brucei unspecified product 0.0078 0.0318 0.4238
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0162 0.149
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0037 0.0112 0.0621
Brugia malayi SET domain containing protein 0.0037 0.0112 0.0617
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0028 0.0066
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.014 0.0621 0.5696
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0016
Plasmodium falciparum cysteine proteinase falcipain 3 0.0056 0.021 0.313
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0006 0.0013
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0018 0.0023 0.0337
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0023 0.0207
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0028 0.0066
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0726 0.1683
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0023 0.0052
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0108 0.0995
Brugia malayi Death domain containing protein 0.0014 0.0002 0.0012
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0052 0.0188 0.0188
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0022 0.0122
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.004 0.0221
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0103 0.0948
Schistosoma mansoni rab6-interacting 0.002 0.0028 0.0066
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0017 0.0015 0.0034
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0291 0.0675
Plasmodium falciparum serine repeat antigen 4 0.0018 0.0023 0.0337
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0018 0.0023 0.0337
Echinococcus granulosus geminin 0.0892 0.4315 1
Toxoplasma gondii thioredoxin reductase 0.015 0.0669 0.2417
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.013 0.0204
Brugia malayi glutathione reductase 0.015 0.0669 0.3698
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0055 0.0736
Giardia lamblia Encystation-specific protease 0.0018 0.0023 0.0431
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0119 0.0518 0.1201
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0106 0.0165
Schistosoma mansoni alpha-glucosidase 0.0139 0.0616 0.1427
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.0412 0.0955
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0094 0.0395 0.3626
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0061 0.0338
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0027 0.015
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0095 0.0343
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0022 0.0329
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0048 0.0112
Onchocerca volvulus 0.0026 0.0061 0.056
Brugia malayi Cytochrome P450 family protein 0.0016 0.0009 0.0052
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0067 0.0263 0.502
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0035 0.0103 0.1543
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0023 0.0052
Loa Loa (eye worm) hypothetical protein 0.0062 0.0235 0.1299
Onchocerca volvulus 0.0124 0.0541 0.4965
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0119 0.0518 0.0812
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0873
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0138 0.032
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.0412 0.6121
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0052 0.0188 0.2504
Toxoplasma gondii P-type ATPase4, putative 0.0084 0.0345 0.1246
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.006 0.0139
Echinococcus multilocularis neuropeptide s receptor 0.0465 0.2217 0.5137
Entamoeba histolytica hypothetical protein 0.0151 0.0673 1
Giardia lamblia Cathepsin L precursor 0.0018 0.0023 0.0431
Onchocerca volvulus 0.0083 0.0337 0.3094
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Schistosoma mansoni peroxidasin 0.0026 0.0061 0.0142
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0018 0.0023 0.0337
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0057 0.0213 0.1175
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0088 0.0364 0.3341
Schistosoma mansoni intermediate filament proteins 0.0027 0.0064 0.0147
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0027 0.052
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0108 0.0995
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0052 0.0188 0.2504
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0081 0.0187
Onchocerca volvulus 0.0029 0.0072 0.0662
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0027 0.0062 0.0062
Echinococcus multilocularis copper transporting ATPase 1 0.0027 0.0062 0.0145
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0035 0.0103 0.0373
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.021 0.0486
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0046 0.0046
Brugia malayi Na,K-ATPase alpha subunit 0.0084 0.0345 0.1906
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.021 0.1923
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0873
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0052 0.0188 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0212 0.1949
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0151 0.0673 0.156
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0204 0.1125
Trypanosoma cruzi cation-transporting ATPase, putative 0.0027 0.0062 0.0098
Echinococcus granulosus cathepsin L cysteine protease 0.004 0.013 0.0302
Loa Loa (eye worm) hypothetical protein 0.0035 0.0102 0.0562
Loa Loa (eye worm) hypothetical protein 0.0049 0.0173 0.0957
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0052 0.0188 0.0262
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0088 0.0364 0.1314
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0023 0.0207
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0106 0.1409
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.012 0.1104
Toxoplasma gondii cation-transporting atpase family protein 0.0017 0.0015 0.0053
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0124
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0022 0.0203
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Echinococcus granulosus cation transporting atpase worm 0.0027 0.0062 0.0145
Schistosoma mansoni netrin receptor unc5 0.0014 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0062 0.0345
Loa Loa (eye worm) hypothetical protein 0.0035 0.0102 0.0562
Entamoeba histolytica cysteine proteinase, putative 0.004 0.013 0.1938
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0103 0.0948
Giardia lamblia Cathepsin B precursor 0.0018 0.0023 0.0431
Brugia malayi fibroinase precursor 0.0018 0.0023 0.0124
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0061 0.0338
Leishmania major DNA damage repair protein, putative 0.0035 0.0106 0.1409
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0265 0.0614
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.021 0.1923
Loa Loa (eye worm) RNA binding protein 0.007 0.0277 0.1532
Schistosoma mansoni type V p-type atpase isoform 0.0027 0.0062 0.0145
Trichomonas vaginalis cation-transporting ATPase, putative 0.0054 0.0195 0.1789
Brugia malayi MH2 domain containing protein 0.0026 0.006 0.0332
Onchocerca volvulus 0.0027 0.0064 0.0583
Trypanosoma brucei P-type H+-ATPase, putative 0.0054 0.0195 0.2601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.005 0.0461
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0046 0.0689
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0138 0.1267
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Echinococcus granulosus Smad4 0.0026 0.006 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0103 0.0948
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0088 0.1312
Plasmodium vivax cation transporting ATPase, putative 0.0027 0.0062 0.0934
Brugia malayi M-phase phosphoprotein, mpp8 0.0124 0.0541 0.299
Trypanosoma brucei DNA damage repair protein, putative 0.0035 0.0106 0.1409
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0103 0.0948
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0107 0.1422
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0335
Entamoeba histolytica hypothetical protein 0.0018 0.0023 0.0335
Schistosoma mansoni lamin 0.0027 0.0064 0.0147
Brugia malayi Papain family cysteine protease containing protein 0.0056 0.021 0.1158
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0023 0.0124
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0088 0.0364 0.3341
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1472 0.7162 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.021 0.0486
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0668 0.1047
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0023 0.0207
Loa Loa (eye worm) doublecortin family protein 0.002 0.0028 0.0156
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0037 0.0112 0.0176
Onchocerca volvulus 0.0026 0.0061 0.056
Trichomonas vaginalis chromobox protein, putative 0.0098 0.0413 0.3795
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.01
Trypanosoma cruzi DNA damage repair protein, putative 0.0035 0.0106 0.0165
Leishmania major P-type H -ATPase, putative 0.0054 0.0195 0.2601
Plasmodium vivax glutathione reductase, putative 0.015 0.0669 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0135 0.1239
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0084 0.0345 0.1906
Schistosoma mansoni cation-transporting atpase worm 0.0027 0.0062 0.0145
Schistosoma mansoni hypothetical protein 0.0038 0.0118 0.0273
Brugia malayi Heterochromatin protein 1 0.0155 0.0694 0.3831
Brugia malayi MH2 domain containing protein 0.0382 0.181 1
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0076 0.0303 0.1675
Trichomonas vaginalis glutathione reductase, putative 0.0052 0.0188 0.1722
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0061 0.056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Echinococcus multilocularis cysteine protease 0.0056 0.021 0.0486
Brugia malayi Membrane calcium atpase protein 3 0.0077 0.0313 0.1727
Echinococcus multilocularis X box binding protein 1 0.0286 0.1336 0.3097
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Entamoeba histolytica hypothetical protein 0.0035 0.0103 0.1535
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.0621 0.8281
Plasmodium vivax vivapain-2 0.0056 0.021 0.313
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0063 0.0579
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0016
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0022 0.0295
Echinococcus multilocularis calcium transporting atpase 0.0103 0.0436 0.101
Trypanosoma brucei DNA polymerase kappa, putative 0.0085 0.035 0.4667
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0337 0.0782
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0162 0.0376
Echinococcus granulosus cathepsin L cysteine proteinase 0.0056 0.021 0.0486
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0342 0.1614 0.2254
Echinococcus multilocularis chromobox protein 1 0.0155 0.0694 0.1608
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0027 0.0062 0.0087
Loa Loa (eye worm) hypothetical protein 0.0235 0.1085 0.5991
Mycobacterium tuberculosis Conserved hypothetical protein 0.0114 0.0491 0.0686
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0023 0.0337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0062 0.0567
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0067 0.0263 0.3504
Giardia lamblia Cathepsin L-like protease 0.0018 0.0023 0.0431
Echinococcus multilocularis cathepsin b 0.0018 0.0023 0.0052
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0022 0.0022
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0022 0.0035
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0018 0.0042
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0077 0.0313 0.0725
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0188 0.0294
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.4025 0.9327
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0135 0.1239
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0181 0.345
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0061 0.0338
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0118 0.1083
Brugia malayi Peroxidasin 0.0026 0.0061 0.0338
Echinococcus granulosus intermediate filament protein 0.0027 0.0064 0.0147
Echinococcus granulosus neuropeptide s receptor 0.0465 0.2217 0.5137
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0151 0.2017
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0119 0.0518 0.187
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0135 0.1239
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.0726 0.4011
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0023 0.0207
Brugia malayi calcium ATPase 0.0041 0.0132 0.0731
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0173 0.0401
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0103 0.0948
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0094 0.0395 0.3626
Loa Loa (eye worm) hypothetical protein 0.0124 0.0541 0.299
Plasmodium vivax vivapain-1 0.004 0.013 0.1948
Echinococcus multilocularis cysteine protease 0.0056 0.021 0.0486
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0027 0.0062 0.1195
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0108 0.0995
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0181 0.0997
Brugia malayi hypothetical protein 0.0124 0.0542 0.2993
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0668 0.1047
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0061 0.0338
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0335
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0106 0.0381
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0151 0.1388
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0018 0.0023 0.0431
Echinococcus multilocularis cation transporting ATPase 13A3 0.0027 0.0062 0.0145
Plasmodium falciparum calcium-transporting ATPase 0.0103 0.0436 0.6509
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0342 0.1614 0.2254
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0018 0.0042
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0094 0.0395 0.3626
Leishmania major cathepsin L-like protease 0.0056 0.021 0.2796
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0081 0.0187
Trypanosoma brucei DNA polymerase IV, putative 0.0134 0.0588 0.7852
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0077 0.0313 0.0725
Schistosoma mansoni alpha-glucosidase 0.0139 0.0616 0.1427
Schistosoma mansoni hypothetical protein 0.0048 0.0167 0.0388
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0023 0.0052
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0188 0.0294
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0022 0.0051
Leishmania major cathepsin L-like protease 0.015 0.0668 0.8915
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Loa Loa (eye worm) hypothetical protein 0.0083 0.0337 0.1864
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0057 0.0213 0.1175
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0108 0.0599
Trichomonas vaginalis MYB, putative 0.0088 0.0366 0.336
Echinococcus granulosus Na:K ATPase alpha subunit 0.0067 0.0263 0.0609
Plasmodium falciparum serine repeat antigen 3 0.0018 0.0023 0.0337
Trypanosoma brucei DNA polymerase kappa, putative 0.014 0.0621 0.8281
Onchocerca volvulus 0.0018 0.0023 0.0207
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0181 0.2409
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.004 0.0221
Toxoplasma gondii cathepsin CPL 0.0056 0.021 0.0756
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0108 0.0391
Brugia malayi Cathepsin L-like precursor 0.0022 0.004 0.0221
Trypanosoma cruzi DNA polymerase kappa, putative 0.014 0.0621 0.0972
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0002 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0235 0.3139
Trypanosoma cruzi cruzipain precursor, putative 0.015 0.0668 0.1047
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0162 0.149
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0431 0.1
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0067 0.0263 0.0609
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.021 0.1923
Onchocerca volvulus 0.0063 0.0242 0.2223
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.0726 0.4011
Echinococcus multilocularis Smad4 0.0026 0.006 0.0139
Echinococcus multilocularis cation transporting atpase worm 0.0027 0.0062 0.0145
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0061 0.0338
Echinococcus granulosus peroxidasin 0.0026 0.0061 0.0142
Loa Loa (eye worm) hypothetical protein 0.0124 0.0542 0.2993
Echinococcus multilocularis protein dispatched 1 0.0048 0.0167 0.0387
Echinococcus granulosus dna polymerase eta 0.0166 0.0749 0.1737
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0023 0.0124
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0381 0.1802 0.2516
Schistosoma mansoni lipoxygenase 0.0055 0.0201 0.0466
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.021 0.0328
Brugia malayi hypothetical protein 0.0122 0.0529 0.2923
Loa Loa (eye worm) hypothetical protein 0.0122 0.0529 0.2923
Echinococcus granulosus microtubule associated protein 2 0.0833 0.4025 0.9327
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0081 0.0187
Onchocerca volvulus 0.0048 0.0167 0.1534
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.021 0.1923
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0094 0.0395 0.5272
Loa Loa (eye worm) calcium ATPase 0.002 0.003 0.0166
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0072 0.0168
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0023 0.0431
Echinococcus granulosus RUN 0.002 0.0028 0.0066
Echinococcus multilocularis lamin 0.0027 0.0064 0.0147
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0151 0.0237
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0134 0.2008
Schistosoma mansoni hypothetical protein 0.0014 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0009 0.0052
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0094 0.0395 0.3626
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0015 0.0053
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0092 0.0383 0.3517
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0103 0.0948
Trypanosoma brucei unspecified product 0.0078 0.0318 0.4238
Trypanosoma brucei protein kinase, putative 0.0051 0.0181 0.2409
Trichomonas vaginalis DNA polymerase eta, putative 0.014 0.0621 0.5696
Brugia malayi hypothetical protein 0.0053 0.0191 0.1055
Leishmania major cathepsin L-like protease 0.0056 0.021 0.2796
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0191 0.2854
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0018 0.0023 0.0337
Entamoeba histolytica cysteine protease, putative 0.0056 0.021 0.3114
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0058 0.0215 0.3192
Brugia malayi Cytochrome P450 family protein 0.0016 0.0009 0.0052
Loa Loa (eye worm) hypothetical protein 0.0119 0.0518 0.2862
Schistosoma mansoni rab6-interacting 0.002 0.0028 0.0066
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0018 0.01
Loa Loa (eye worm) hypothetical protein 0.0053 0.0191 0.1055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0118 0.0651
Echinococcus granulosus cathepsin L 0.0018 0.0023 0.0052
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0338
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0726 0.1683
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0061 0.056
Schistosoma mansoni ap endonuclease 0.0018 0.0022 0.0051
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0181 0.1657
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0102 0.0431 0.1
Brugia malayi hypothetical protein 0.0235 0.1085 0.5991
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0027 0.0062 0.0929
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0027 0.0062 0.0345
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0181 0.1657
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0089 0.037 0.0858
Loa Loa (eye worm) MH2 domain-containing protein 0.0382 0.181 1
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0067 0.0263 0.0609
Leishmania major calcium-transporting ATPase, putative 0.0067 0.0263 0.3504
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0191 0.0299
Onchocerca volvulus 0.0056 0.021 0.1922
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0077 0.0313 0.0725
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0337 0.0782
Loa Loa (eye worm) fibroinase 0.0056 0.021 0.1158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0976
Schistosoma mansoni phosphoserine phosphatase 0.0017 0.0015 0.0034
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0027 0.0098
Echinococcus multilocularis expressed conserved protein 0.0092 0.0383 0.0887
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0015 0.0034
Plasmodium falciparum thioredoxin reductase 0.015 0.0669 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0062 0.0345
Schistosoma mansoni DNA helicase recq5 0.0019 0.0027 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0106 0.0976
Loa Loa (eye worm) hypothetical protein 0.0031 0.0082 0.0455
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0119 0.0518 0.774
Giardia lamblia GTOR 0.0045 0.0151 0.289
Toxoplasma gondii cathepsin B 0.0018 0.0023 0.0081
Giardia lamblia Cathepsin L precursor 0.0018 0.0023 0.0431
Loa Loa (eye worm) cysteine protease 0.0056 0.021 0.1158
Echinococcus granulosus Chromo domain 0.0035 0.0103 0.0239
Trypanosoma cruzi cysteine peptidase, putative 0.004 0.013 0.0204
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0022 0.0051
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0006 0.0013
Schistosoma mansoni DNA helicase recq1 0.0019 0.0027 0.0063
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0103 0.1535
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0037 0.0112 0.0176
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0103 0.1535
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0201 0.0466
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0191 0.0299
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0038 0.012 0.0662
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0103 0.0373
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0291 0.0675
Loa Loa (eye worm) hypothetical protein 0.0035 0.0103 0.0571
Toxoplasma gondii cathepsin CPC1 0.0018 0.0023 0.0081
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0419 0.0972
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0181 0.0418
Trichomonas vaginalis cation-transporting ATPase, putative 0.0027 0.0062 0.0574
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0103 0.0239
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0052 0.0188 0.2803
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0234 0.0543
Leishmania major DNA polymerase kappa, putative 0.0035 0.0106 0.1409
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0056 0.021 0.1158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0207
Trypanosoma cruzi P-type H+-ATPase, putative 0.0054 0.0195 0.0305
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0002 0.0005
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0181 0.0652
Plasmodium vivax copper-transporting ATPase, putative 0.0027 0.0062 0.0934
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0046 0.0167
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0103 0.0948
Trichomonas vaginalis cation-transporting ATPase, putative 0.0094 0.0395 0.3626
Schistosoma mansoni cpg binding protein 0.003 0.008 0.0186
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0003 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0095 0.0873
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0023 0.0052
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0108 0.0995
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0088 0.0364 0.3341
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0094 0.0395 0.5272
Schistosoma mansoni hypothetical protein 0.0024 0.0048 0.0112
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0009 0.0052
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0118 0.0651
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0028 0.0066
Leishmania major hypothetical protein, conserved 0.0053 0.0191 0.255
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0023 0.0207
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0088 0.0366 0.336
Onchocerca volvulus 0.0049 0.0173 0.1589
Giardia lamblia Cathepsin L precursor 0.0018 0.0023 0.0431
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0023 0.0337
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0124
Brugia malayi hypothetical protein 0.002 0.0028 0.0156
Brugia malayi Associated with TFs and helicases family protein 0.0035 0.0103 0.0571
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0119 0.0518 0.1201
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0015 0.0053
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0102 0.1511
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0201 0.0466
Schistosoma mansoni cathepsin s 0.0022 0.004 0.0093
Toxoplasma gondii P-type ATPase PMA1 0.0054 0.0195 0.0704
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0023 0.0052
Trypanosoma brucei chrX additional, unordered contigs 0.0035 0.0106 0.1409
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0108 0.0599
Giardia lamblia Cathepsin B precursor 0.0018 0.0023 0.0431
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0084 0.0345 0.08
Mycobacterium tuberculosis Probable reductase 0.0342 0.1614 0.2254
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0052 0.0188 0.0435
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0668 0.8915
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0055 0.0086
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.205 1 1
Plasmodium falciparum DNA repair protein REV1, putative 0.0035 0.0106 0.1578
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0135 0.1239
Trypanosoma brucei trypanothione reductase 0.015 0.0669 0.8933
Brugia malayi cathepsin L-like precursor 0.0035 0.0102 0.0562
Schistosoma mansoni atpase class VI type 11c 0.0017 0.0015 0.0034
Trypanosoma cruzi trypanothione reductase, putative 0.015 0.0669 0.1049
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0006 0.0031
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0103 0.0373
Echinococcus multilocularis RUN 0.002 0.0028 0.0066
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0035 0.0103 0.0571
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0046 0.0046
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.013 0.0204
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0077 0.0313 0.1129
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0027 0.0062 0.0087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.021 0.1923
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0108 0.0995
Trichomonas vaginalis mercuric reductase, putative 0.0052 0.0188 0.1722
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0015 0.0034
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.1096 0.6052
Brugia malayi E1-E2 ATPase family protein 0.0054 0.0195 0.1077
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0023 0.0207
Leishmania major DNA polymerase kappa, putative 0.012 0.0523 0.6981
Trypanosoma cruzi cysteine peptidase, putative 0.1314 0.6384 1
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0066 0.0255 0.04
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0094 0.0395 0.5871
Brugia malayi Cathepsin L-like cysteine proteinase 0.0035 0.0102 0.0562
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.012 0.1104
Loa Loa (eye worm) hypothetical protein 0.0068 0.0265 0.1464
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0188 0.0294
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0138 0.032
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0046 0.0064
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0188 0.0294
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0006 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0006 0.0052
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0135 0.1239
Entamoeba histolytica cysteine protease, putative 0.004 0.013 0.1938
Echinococcus multilocularis dna polymerase eta 0.0166 0.0749 0.1737
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0335
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.012 0.0523 0.6981
Trypanosoma cruzi cysteine protease, putative 0.004 0.013 0.0204
Brugia malayi hypothetical protein 0.0017 0.0015 0.0081
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0089 0.037 0.0858
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0035 0.0103 0.0239
Brugia malayi follicle stimulating hormone receptor 0.0237 0.1096 0.6052
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0022 0.0295
Schistosoma mansoni cation-transporting atpase worm 0.0027 0.0062 0.0145
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.002 0.003 0.0447
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0081 0.0187
Chlamydia trachomatis metal transport ATPase 0.0027 0.0062 0.0062
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0181 0.2409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0006 0.0052
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0103 0.0948
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0052 0.0188 0.2803
Onchocerca volvulus 0.0124 0.0541 0.4965
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0088 0.0364 0.3341
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0106 0.1409
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0337 0.0782
Trichomonas vaginalis MYB72, putative 0.0088 0.0364 0.3341

Activities

Activity type Activity value Assay description Source Reference
Potency (binding) = 8.9125 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 70.7946 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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