Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.2065 | 0.6723 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0053 | 0.0174 |
Chlamydia trachomatis | pyruvate kinase | 0.0033 | 0.0312 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0053 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.031 | 0.1014 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0826 | 0.27 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0468 | 0.1531 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.0053 | 0.0174 |
Brugia malayi | Inositol-1 | 0.0038 | 0.0372 | 0.1215 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0053 | 0.0026 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0372 | 0.3614 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0099 | 0.0323 |
Brugia malayi | PHD-finger family protein | 0.0027 | 0.0239 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0099 | 0.0323 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0053 | 0.0174 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0099 | 0.0323 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0137 | 0.0363 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0099 | 0.0236 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0745 | 0.8438 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0053 | 0.0174 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0053 | 0.0174 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0038 | 0.0372 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0492 | 0.1609 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.012 | 0.0093 |
Brugia malayi | TAR-binding protein | 0.0264 | 0.3058 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0264 | 0.3058 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0053 | 0.0086 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0312 | 0.0286 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.017 | 0.0471 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.0053 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0826 | 0.27 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0053 | 0.0086 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0027 | 0.0089 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0053 | 0.0174 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0053 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0826 | 0.27 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0189 | 0.2161 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0076 | 0.0826 | 0.0948 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0076 | 0.0826 | 0.0948 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0019 | 0.0137 | 0.0363 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0826 | 0.27 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0137 | 0.0448 |
Onchocerca volvulus | 0.0011 | 0.0053 | 0.0122 | |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0312 | 0.1021 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0193 | 0.063 |
Echinococcus multilocularis | muscleblind protein | 0.0162 | 0.1848 | 0.1826 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0372 | 0.3614 |
Plasmodium vivax | pyruvate kinase, putative | 0.0033 | 0.0312 | 0.2729 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.0745 | 0.237 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0033 | 0.0312 | 0.2783 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0053 | 0.0086 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.0053 | 0.0174 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0053 | 0.0086 |
Echinococcus multilocularis | pyruvate kinase | 0.0026 | 0.0229 | 0.0202 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.012 | 0.0093 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0076 | 0.0826 | 0.2634 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0053 | 0.0086 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0138 | 0.1556 | 0.1533 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0053 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0053 | 0.0174 |
Mycobacterium ulcerans | hypothetical protein | 0.0076 | 0.0826 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0053 | 0.0174 |
Leishmania major | pyruvate kinase | 0.0033 | 0.0312 | 0.2783 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0076 | 0.0826 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0053 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0312 | 0.1021 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0053 | 0.0174 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0372 | 0.1152 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0381 | 0.1168 |
Plasmodium falciparum | pyruvate kinase | 0.0033 | 0.0312 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0138 | 0.1556 | 0.5043 |
Onchocerca volvulus | 0.0076 | 0.0826 | 0.3742 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0826 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0076 | 0.0826 | 0.27 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.017 | 0.0471 |
Schistosoma mansoni | zinc finger protein | 0.0017 | 0.0114 | 0.0288 |
Onchocerca volvulus | 0.0076 | 0.0826 | 0.3742 | |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.0372 | 0.0345 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0488 | 0.5724 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0372 | 0.1136 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0076 | 0.0826 | 0.2634 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0053 | 0.0026 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0138 | 0.1556 | 0.5043 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0033 | 0.0312 | 0.2783 |
Schistosoma mansoni | survival motor neuron protein | 0.0051 | 0.0528 | 0.1653 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.031 | 0.0934 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0053 | 0.0086 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.017 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0413 | 0.135 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0053 | 0.0026 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.007 | 0.0745 | 0.072 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0053 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0027 | 0.0089 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0017 | 0.012 | 0.116 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0099 | 0.0236 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0023 | 0.0193 | 0.063 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0019 | 0.0137 | 0.0363 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.0053 | 0.0174 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.0381 | 0.0355 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0033 | 0.0312 | 0.1021 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0138 | 0.1556 | 0.5087 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0443 | 0.145 |
Mycobacterium leprae | Probable lipase LipE | 0.0076 | 0.0826 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0053 | 0.0086 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.0053 | 0.0026 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0099 | 0.0072 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0745 | 0.8438 |
Mycobacterium ulcerans | beta-lactamase | 0.0076 | 0.0826 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0076 | 0.0826 | 0.0948 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0076 | 0.0826 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0053 | 0.0086 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.007 | 0.0745 | 0.237 |
Echinococcus multilocularis | geminin | 0.0181 | 0.2065 | 0.2043 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0099 | 0.0072 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.012 | 0.0306 |
Brugia malayi | hypothetical protein | 0.0252 | 0.2915 | 0.953 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0053 | 0.0026 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0099 | 0.0236 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0009 | 0.0027 | 0.0089 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.0372 | 0.1136 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.0324 | 0.0021 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.0372 | 0.4313 |
Schistosoma mansoni | pyruvate kinase | 0.0017 | 0.012 | 0.0306 |
Brugia malayi | beta-lactamase | 0.0076 | 0.0826 | 0.27 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0076 | 0.0826 | 0.0948 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0025 | 0.0208 | 0.0182 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0053 | 0.0174 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0076 | 0.0826 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0053 | 0.0086 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0138 | 0.1556 | 0.1533 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.0053 | 0.0122 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0312 | 0.1337 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.0053 | 0.0174 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0033 | 0.0312 | 0.2783 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.2065 | 0.6723 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0019 | 0.0137 | 0.011 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0053 | 0.0174 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0099 | 0.0236 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.0053 | 0.0174 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0137 | 0.0363 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0745 | 0.8438 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0076 | 0.0826 | 0.27 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0051 | 0.0528 | 0.1727 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0053 | 0.0026 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.0053 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0027 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1848 | 0.6044 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0372 | 0.1136 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0009 | 0.0027 | 0.0089 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0065 | 0.0689 | 0.0663 |
Toxoplasma gondii | ABC1 family protein | 0.0076 | 0.0826 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.0053 | 0.0122 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0053 | 0.0086 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0053 | 0.0086 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.1556 | 0.5043 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.2161 | 0.7067 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0053 | 0.0026 |
Trichomonas vaginalis | esterase, putative | 0.0076 | 0.0826 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0162 | 0.1848 | 0.6044 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0033 | 0.0312 | 0.2783 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.0324 | 0.0223 |
Echinococcus granulosus | geminin | 0.0181 | 0.2065 | 0.6723 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0076 | 0.0826 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0099 | 0.0323 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0492 | 0.1609 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0053 | 0.0174 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.031 | 0.1014 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0492 | 0.1609 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0826 | 0.27 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0053 | 0.0086 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0372 | 0.3614 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0019 | 0.0137 | 0.011 |
Brugia malayi | N-terminal motif family protein | 0.0189 | 0.2161 | 0.7067 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0053 | 0.0174 |
Schistosoma mansoni | tar DNA-binding protein | 0.0264 | 0.3058 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0264 | 0.3058 | 0.304 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.012 | 0.0306 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0099 | 0.0072 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.0053 | 0.0174 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.007 | 0.0745 | 0.08 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0076 | 0.0826 | 0.0948 |
Schistosoma mansoni | bromodomain containing protein | 0.0069 | 0.0735 | 0.2335 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0076 | 0.0826 | 0.27 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.0053 | 0.0174 |
Echinococcus granulosus | tar DNA binding protein | 0.0264 | 0.3058 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0137 | 0.0363 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0312 | 0.1021 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0053 | 0.0174 |
Echinococcus granulosus | muscleblind protein | 0.0162 | 0.1848 | 0.6008 |
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.0412 | 0.1347 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.0053 | 0.0174 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0076 | 0.0826 | 0.0801 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0076 | 0.0826 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0826 | 0.27 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0826 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0114 | 0.0288 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0027 | 0.0089 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.0053 | 0.0122 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0138 | 0.1556 | 0.5087 |
Mycobacterium tuberculosis | Conserved protein | 0.0076 | 0.0826 | 0.0948 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0831 | 0.2718 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0033 | 0.0312 | 0.3573 |
Leishmania major | pyruvate kinase | 0.0033 | 0.0312 | 0.2783 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0053 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0099 | 0.0236 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0053 | 0.0086 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0264 | 0.3058 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0099 | 0.0236 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0009 | 0.0027 | 0.0089 |
Loa Loa (eye worm) | RNA binding protein | 0.0264 | 0.3058 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.0372 | 0.1215 |
Mycobacterium ulcerans | lipase LipD | 0.0076 | 0.0826 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0082 | 0.0887 | 0.2899 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0053 | 0.0086 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.0372 | 0.1152 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0076 | 0.0826 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0252 | 0.2915 | 0.953 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0027 | 0.0089 |
Schistosoma mansoni | tar DNA-binding protein | 0.0264 | 0.3058 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0264 | 0.3058 | 1 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.001 | 0.0036 | 0.0119 |
Loa Loa (eye worm) | TAR-binding protein | 0.0264 | 0.3058 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0264 | 0.3058 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0076 | 0.0826 | 0.0948 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0162 | 0.1848 | 0.1826 |
Leishmania major | hypothetical protein, conserved | 0.0076 | 0.0826 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.0053 | 0.0174 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0053 | 0.0086 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0252 | 0.2915 | 0.9526 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.0053 | 0.0174 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0312 | 0.1021 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0053 | 0.0174 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0252 | 0.2915 | 0.2895 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0076 | 0.0826 | 0.0948 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.0053 | 0.0174 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0312 | 0.0941 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.0745 | 0.237 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0065 | 0.0689 | 0.2183 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0027 | 0.0089 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0053 | 0.0174 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0492 | 0.1609 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.007 | 0.0745 | 0.8873 |
Mycobacterium leprae | conserved hypothetical protein | 0.0076 | 0.0826 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0099 | 0.0236 |
Brugia malayi | DIX domain containing protein | 0.0009 | 0.0027 | 0.0089 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.0053 | 0.0174 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.1556 | 0.5043 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.012 | 0.0093 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0312 | 0.0941 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0372 | 0.1152 |
Schistosoma mansoni | tar DNA-binding protein | 0.0264 | 0.3058 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0208 | 0.0597 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.0053 | 0.0174 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0076 | 0.0826 | 0.0948 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0053 | 0.0174 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0033 | 0.0312 | 0.1021 |
Onchocerca volvulus | 0.0051 | 0.0528 | 0.2348 | |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0025 | 0.0208 | 0.0597 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0312 | 0.0286 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.0053 | 0.0086 |
Brugia malayi | beta-lactamase family protein | 0.0076 | 0.0826 | 0.27 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.0053 | 0.0174 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0076 | 0.0826 | 0.2634 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0053 | 0.0026 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.0053 | 0.0174 |
Giardia lamblia | Pyruvate kinase | 0.0033 | 0.0312 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0138 | 0.1556 | 0.5043 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0372 | 0.3614 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0053 | 0.0174 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0312 | 0.1337 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0312 | 0.1337 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0027 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.1848 | 0.6044 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0312 | 0.0941 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.012 | 0.0306 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0312 | 0.0941 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.0372 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0076 | 0.0826 | 0.27 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0076 | 0.0826 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0053 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0528 | 0.1653 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0183 | 0.06 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0145 | 0.0474 |
Brugia malayi | RNA binding protein | 0.0264 | 0.3058 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0137 | 0.0363 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0053 | 0.0086 |
Onchocerca volvulus | 0.0076 | 0.0826 | 0.3742 | |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.0372 | 0.1152 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0076 | 0.0826 | 0.0948 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0183 | 0.0516 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0076 | 0.0826 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.007 | 0.0745 | 0.8996 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.0053 | 0.0174 |
Plasmodium vivax | hypothetical protein, conserved | 0.0076 | 0.0826 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 44.6684 uM | PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 79.4328 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.