Detailed information for compound 1454300

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 330.362 | Formula: C15H14N4O3S
  • H donors: 2 H acceptors: 4 LogP: 1.22 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=O)CSc1nnc(n1Cc1ccco1)c1ccc(cc1)O
  • InChi: 1S/C15H14N4O3S/c16-13(21)9-23-15-18-17-14(10-3-5-11(20)6-4-10)19(15)8-12-2-1-7-22-12/h1-7,20H,8-9H2,(H2,16,21)
  • InChiKey: XBETXYZFPWOTQK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens caspase 1, apoptosis-related cysteine peptidase Starlite/ChEMBL No references
Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 Starlite/ChEMBL No references
Homo sapiens caspase 7, apoptosis-related cysteine peptidase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma japonicum ko:K00022 3-hydroxyacyl-CoA dehydrogenase [EC1.1.1.35], putative Get druggable targets OG5_129031 All targets in OG5_129031
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus granulosus caspase 3 Get druggable targets OG5_130238 All targets in OG5_130238
Leishmania braziliensis 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Schistosoma mansoni caspase-3 (C14 family) Get druggable targets OG5_130238 All targets in OG5_130238
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis caspase Get druggable targets OG5_130238 All targets in OG5_130238
Schistosoma mansoni caspase-7 (C14 family) Get druggable targets OG5_130238 All targets in OG5_130238
Schistosoma japonicum ko:K02187 caspase 3, apoptosis-related cysteine protease, putative Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus granulosus caspase Get druggable targets OG5_130238 All targets in OG5_130238
Leishmania infantum 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Cryptosporidium hominis scully CG7113-PA Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis caspase 3 Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase Get druggable targets OG5_130238 All targets in OG5_130238
Schistosoma japonicum ko:K04397 caspase 7, apoptosis-related cysteine protease, putative Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase Get druggable targets OG5_130238 All targets in OG5_130238
Leishmania mexicana 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania donovani 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative Get druggable targets OG5_129031 All targets in OG5_129031
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II Get druggable targets OG5_129031 All targets in OG5_129031
Cryptosporidium parvum scully CG7113-PA, putative Get druggable targets OG5_129031 All targets in OG5_129031
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 Get druggable targets OG5_129031 All targets in OG5_129031
Mycobacterium ulcerans short-chain type dehydrogenase/reductase Get druggable targets OG5_129031 All targets in OG5_129031
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Cell death protein 3 precursor caspase 7, apoptosis-related cysteine peptidase 303 aa 256 aa 37.1 %
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase hydroxysteroid (17-beta) dehydrogenase 10 252 aa 251 aa 24.7 %
Echinococcus granulosus caspase 8 caspase 1, apoptosis-related cysteine peptidase 383 aa 312 aa 26.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Kinase, CDC7 0.0098 0.0469 0.0776
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0171 0.1235 0.1305
Echinococcus granulosus tyrosine kinase 0.0232 0.1875 0.1875
Loa Loa (eye worm) hypothetical protein 0.0119 0.069 0.0727
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0415 0.3793 0.4576
Entamoeba histolytica PH domain containing protein kinase, putative 0.0129 0.0801 0.1525
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0397 0.3608 0.4352
Echinococcus multilocularis expressed conserved protein 0.0142 0.0931 0.1123
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0276 0.2336 0.2818
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0136 0.087 0.1647
Trypanosoma brucei protein kinase, putative 0.0099 0.0488 0.0919
Schistosoma mansoni serine/threonine protein kinase 0.0275 0.233 0.4011
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0465 0.0801
Loa Loa (eye worm) hypothetical protein 0.0061 0.0081 0.008
Entamoeba histolytica hypothetical protein 0.0061 0.0081 0.0154
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.029 0.2485 0.4724
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Brugia malayi Protein kinase domain containing protein 0.0345 0.3065 0.3248
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0056 0.0031 0.0027
Echinococcus multilocularis tyrosine protein kinase HCK 0.0167 0.1193 0.1439
Loa Loa (eye worm) TK/INSR protein kinase 0.0447 0.4133 0.4383
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0976 0.1681
Brugia malayi Protein kinase c protein 2 0.0224 0.1797 0.1902
Trypanosoma cruzi NIMA-related kinase, putative 0.0059 0.0066 0.0115
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.1268 0.2413
Plasmodium vivax casein kinase 1, putative 0.0116 0.0664 0.1254
Schistosoma mansoni tyrosine kinase 0.0607 0.5809 1
Giardia lamblia Kinase, NEK 0.0143 0.0947 0.1698
Echinococcus multilocularis NCK adaptor protein 0.0113 0.0626 0.0756
Echinococcus multilocularis calcium activated potassium channel 0.0142 0.0934 0.1126
Brugia malayi Protein kinase domain containing protein 0.0116 0.0665 0.07
Loa Loa (eye worm) TK/FER protein kinase 0.0116 0.0665 0.07
Echinococcus multilocularis CDC7 cell division cycle 7 0.0098 0.0469 0.0566
Echinococcus multilocularis N chimaerin 0.0126 0.0763 0.0921
Brugia malayi Variant SH3 domain containing protein 0.0079 0.0272 0.0282
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.1771 0.3048
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0284 0.2424 0.2424
Echinococcus multilocularis tyrosine protein kinase Srms 0.0232 0.1875 0.2261
Echinococcus granulosus protein kinase c eta type 0.0061 0.0081 0.0081
Echinococcus granulosus cyclin dependent kinase 1 0.0126 0.0768 0.0768
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0066 0.0125
Echinococcus granulosus tyrosine protein kinase Fyn 0.0276 0.2336 0.2336
Trichomonas vaginalis CAMK family protein kinase 0.0275 0.233 0.4435
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0079 0.0273 0.0329
Loa Loa (eye worm) hypothetical protein 0.0061 0.0081 0.008
Entamoeba histolytica protein kinase domain containing protein 0.0174 0.1268 0.2414
Echinococcus multilocularis casein kinase I gamma 0.0219 0.1742 0.2101
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0116 0.0664 0.1254
Trichomonas vaginalis STE family protein kinase 0.0143 0.0947 0.1802
Echinococcus granulosus contactin 0.0059 0.0067 0.0067
Trypanosoma brucei Serine/threonine-protein kinase NEK16, putative 0.0059 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.0201 0.1554 0.1643
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.012 0.0709 0.0709
Entamoeba histolytica protein kinase, putative 0.0146 0.0976 0.1859
Echinococcus granulosus mitogen activated protein kinase 3 0.0092 0.0407 0.0407
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0093 0.0416 0.0782
Loa Loa (eye worm) hypothetical protein 0.0454 0.4203 0.4457
Echinococcus multilocularis casein kinase ii subunit alpha 0.0174 0.1268 0.153
Trichomonas vaginalis AGC family protein kinase 0.0221 0.1768 0.3364
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0062 0.0094 0.0178
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0356 0.3179 0.335
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0122 0.0721 0.0721
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0976 0.1858
Entamoeba histolytica protein kinase domain containing protein 0.0093 0.0421 0.0801
Echinococcus multilocularis casein kinase I alpha 0.0116 0.0664 0.0801
Echinococcus granulosus tyrosine protein kinase Src64B 0.0276 0.2336 0.2336
Schistosoma mansoni tensin 0.0065 0.0128 0.022
Loa Loa (eye worm) IKK protein kinase 0.0952 0.9423 1
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0976 0.1858
Echinococcus granulosus unc 13 munc13 0.0066 0.0133 0.0133
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0136 0.087 0.0918
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0709 0.122
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.1235 0.2126
Loa Loa (eye worm) hypothetical protein 0.0097 0.0465 0.0488
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.019 0.1436 0.1518
Echinococcus multilocularis titin 0.008 0.0285 0.0343
Echinococcus multilocularis insulin receptor 0.0447 0.4133 0.4985
Schistosoma mansoni protein kinase C mu 0.0061 0.0081 0.0139
Schistosoma mansoni protein kinase 0.0112 0.0623 0.1073
Echinococcus granulosus suppressor of cytokine signaling 7 0.0065 0.0128 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0141 0.0926 0.0977
Schistosoma mansoni tyrosine kinase 0.0082 0.0307 0.0529
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0065 0.0128 0.0128
Echinococcus granulosus casein kinase I delta 0.0116 0.0664 0.0664
Schistosoma mansoni titin 0.008 0.0285 0.049
Echinococcus multilocularis c src tyrosine kinase 0.016 0.1127 0.1359
Trichomonas vaginalis CAMK family protein kinase 0.0275 0.233 0.4435
Entamoeba histolytica protein kinase , putative 0.0554 0.5253 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0065 0.0128 0.0129
Onchocerca volvulus 0.0085 0.0338 0.0324
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0146 0.0976 0.1849
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0934 0.1607
Brugia malayi Fibronectin type III domain containing protein 0.0102 0.0514 0.054
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0356 0.3179 0.3369
Entamoeba histolytica protein kinase domain containing protein 0.0209 0.1633 0.3108
Trypanosoma brucei protein kinase, putative 0.0093 0.0421 0.0791
Brugia malayi Protein kinase domain containing protein 0.0116 0.0665 0.07
Trichomonas vaginalis AGC family protein kinase 0.0221 0.1768 0.3364
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Schistosoma mansoni serine/threonine protein kinase 0.0207 0.1613 0.2777
Entamoeba histolytica protein kinase domain containing protein 0.0146 0.0976 0.1859
Echinococcus multilocularis activin receptor type 0.0454 0.4201 0.5067
Schistosoma mansoni rap gtpase-activating protein 0.0085 0.0338 0.0582
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0112 0.0623 0.0752
Echinococcus multilocularis cyclin dependent kinase 1 0.0126 0.0768 0.0927
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0276 0.2336 0.2818
Echinococcus granulosus caspase 0.0141 0.0927 0.0927
Schistosoma mansoni protein kinase 0.0094 0.043 0.0741
Plasmodium falciparum NIMA related kinase 1 0.0143 0.0947 0.1794
Echinococcus granulosus RNA directed DNA polymerase 0.0117 0.0673 0.0673
Giardia lamblia Kinase, CMGC MAPK 0.0092 0.0407 0.0656
Trichomonas vaginalis AGC family protein kinase 0.012 0.0709 0.1348
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0062 0.0094 0.0178
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0163 0.1158 0.1158
Loa Loa (eye worm) AGC/AKT protein kinase 0.0332 0.2924 0.3099
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0599 0.573 0.6078
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0276 0.2336 0.2818
Onchocerca volvulus 0.0065 0.0128 0.01
Echinococcus granulosus active breakpoint cluster region 0.0103 0.053 0.053
Echinococcus multilocularis caspase 8 0.0053 0.0006 0.0007
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0168 0.1208 0.1277
Echinococcus multilocularis cyclin dependent kinase 0.0126 0.0768 0.0927
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0146 0.0976 0.1849
Echinococcus granulosus ephrin type A receptor 4 A 0.0114 0.0644 0.0644
Brugia malayi Protein kinase domain containing protein 0.0171 0.1235 0.1305
Brugia malayi Temporarily assigned gene name protein 59 0.0085 0.0338 0.0353
Echinococcus granulosus CDC7 cell division cycle 7 0.0098 0.0469 0.0469
Schistosoma mansoni serine/threonine protein kinase 0.0384 0.347 0.5974
Toxoplasma gondii AGC kinase 0.0323 0.2832 0.5385
Echinococcus multilocularis cyclin dependent kinase 9 0.0086 0.0348 0.042
Entamoeba histolytica casein kinase, putative 0.0174 0.1268 0.2414
Entamoeba histolytica protein kinase domain containing protein 0.0554 0.5253 1
Echinococcus multilocularis roundabout 2 0.0059 0.0067 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.0769 0.1323
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Loa Loa (eye worm) AGC/PKA protein kinase 0.012 0.0709 0.0746
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0091 0.04 0.0751
Echinococcus granulosus protein tyrosine kinase 0.03 0.2593 0.2593
Entamoeba histolytica protein kinase, putative 0.0201 0.1557 0.2964
Echinococcus multilocularis neuroglian 0.0119 0.0692 0.0835
Loa Loa (eye worm) protein kinase domain-containing protein 0.0219 0.1742 0.1844
Schistosoma mansoni adapter molecule crk 0.0109 0.0589 0.1015
Brugia malayi Protein kinase domain containing protein 0.0126 0.0768 0.081
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Giardia lamblia Kinase, CMGC CK2 0.0174 0.1268 0.2317
Echinococcus granulosus serine:threonine protein kinase 3 0.0262 0.2192 0.2192
Echinococcus granulosus cyclin dependent kinase 5 0.0126 0.0768 0.0768
Entamoeba histolytica p21-activated kinase 0.0103 0.0522 0.0995
Loa Loa (eye worm) hypothetical protein 0.0273 0.2308 0.2444
Onchocerca volvulus 0.0116 0.0665 0.0673
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Loa Loa (eye worm) hypothetical protein 0.0085 0.0338 0.0353
Echinococcus multilocularis nervana 2 0.0122 0.0721 0.087
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0931 0.1603
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0246 0.2028 0.2446
Loa Loa (eye worm) TK protein kinase 0.0232 0.1875 0.1984
Loa Loa (eye worm) hypothetical protein 0.0215 0.1695 0.1794
Brugia malayi Immunoglobulin I-set domain containing protein 0.0056 0.0031 0.0027
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0146 0.0972 0.1841
Schistosoma mansoni hypothetical protein 0.0085 0.0338 0.0582
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0065 0.0128 0.0128
Giardia lamblia Kinase, AGC AKT 0.0124 0.0751 0.1319
Schistosoma mansoni protein kinase 0.0186 0.1395 0.2401
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0065 0.0128 0.0128
Echinococcus granulosus insulin receptor 0.0447 0.4133 0.4133
Loa Loa (eye worm) AGC/PKN protein kinase 0.0329 0.2894 0.3067
Echinococcus granulosus hypothetical protein 0.0065 0.0128 0.0128
Schistosoma mansoni protein kinase 0.0093 0.0421 0.0725
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0172 0.0177
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0127 0.0775 0.0775
Echinococcus multilocularis 0.0101 0.0503 0.0607
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0172 0.1251 0.2372
Echinococcus granulosus casein kinase I alpha 0.0116 0.0664 0.0664
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0275 0.233 0.4429
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0217 0.1724 0.3275
Brugia malayi Serine/threonine-protein kinase SULU 0.0414 0.3786 0.4014
Loa Loa (eye worm) hypothetical protein 0.0273 0.2308 0.2444
Echinococcus multilocularis serine:threonine protein kinase N2 0.0128 0.0783 0.0944
Brugia malayi SH2 domain containing protein 0.0415 0.3793 0.4022
Echinococcus multilocularis RNA directed DNA polymerase 0.0117 0.0673 0.0811
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0246 0.2028 0.2028
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0109 0.0589 0.1015
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0097 0.0465 0.0875
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Brugia malayi C1-like domain containing protein 0.0243 0.1991 0.2108
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0059 0.0067 0.0081
Loa Loa (eye worm) hypothetical protein 0.0474 0.4419 0.4686
Loa Loa (eye worm) TK/FER protein kinase 0.0116 0.0665 0.07
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0554 0.5253 1
Echinococcus granulosus dual specificity 0.0146 0.0976 0.0976
Echinococcus granulosus fibroblast growth factor receptor 4 0.0246 0.2028 0.2028
Plasmodium falciparum glycogen synthase kinase 3 0.0136 0.087 0.1647
Schistosoma mansoni ste20-related kinase 0.0211 0.1659 0.2855
Brugia malayi cyclin-dependent kinase 9 0.0086 0.0348 0.0364
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0192 0.1459 0.1459
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0127 0.0775 0.0935
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0059 0.0067 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0172 0.0172
Brugia malayi Protein kinase domain containing protein 0.0215 0.1695 0.1794
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0059 0.0066 0.0115
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0092 0.0407 0.0764
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0093 0.0416 0.0782
Brugia malayi Pleckstrin Homology Domain 0.0069 0.0173 0.0177
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0356 0.3179 0.3369
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Schistosoma mansoni tensin-related 0.0065 0.0128 0.022
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0085 0.0338 0.0582
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0097 0.0465 0.0561
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.016 0.1128 0.2137
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0207 0.1613 0.1946
Trichomonas vaginalis CAMK family protein kinase 0.0122 0.073 0.1389
Trichomonas vaginalis CAMK family protein kinase 0.0122 0.073 0.1389
Onchocerca volvulus 0.0116 0.0665 0.0673
Giardia lamblia Kinase, CMGC GSK 0.0136 0.087 0.155
Loa Loa (eye worm) hypothetical protein 0.0176 0.1287 0.136
Onchocerca volvulus 0.0065 0.0128 0.01
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0276 0.2336 0.2818
Giardia lamblia Kinase, NEK 0.0143 0.0947 0.1698
Brugia malayi Protein kinase domain containing protein 0.0287 0.2456 0.2601
Brugia malayi hypothetical protein 0.0056 0.0028 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0976 0.1858
Trypanosoma cruzi cdc2-related kinase 3 0.0126 0.0768 0.1453
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0107 0.0565 0.1075
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0101 0.0503 0.0528
Echinococcus granulosus cGMP dependent protein kinase 1 0.0142 0.0931 0.0931
Schistosoma mansoni cell adhesion molecule 0.0059 0.0067 0.0116
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0276 0.2336 0.2818
Trypanosoma cruzi Serine/threonine-protein kinase NEK16, putative 0.0059 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0054 0.0016 0.001
Trichomonas vaginalis AGC family protein kinase 0.0554 0.5253 1
Trichomonas vaginalis AGC family protein kinase 0.023 0.186 0.354
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0238 0.1936 0.205
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0126 0.0768 0.1453
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0126 0.0768 0.1453
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0089 0.0384 0.0401
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0063 0.0107 0.0107
Schistosoma mansoni tensin-related 0.0065 0.0128 0.022
Brugia malayi SH2 domain containing protein 0.0065 0.0128 0.0129
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0235 0.191 0.191
Giardia lamblia Kinase, STE STE20 0.0093 0.0416 0.0675
Echinococcus granulosus dual specificity mitogen activated protein 0.0188 0.1413 0.1413
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0006 0.001
Schistosoma mansoni vam6/vps39 related 0.0085 0.0338 0.0582
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.016 0.1128 0.2137
Brugia malayi Protein kinase domain containing protein 0.0599 0.573 0.6078
Entamoeba histolytica protein kinase, putative 0.0332 0.2924 0.5566
Brugia malayi Variant SH3 domain containing protein 0.0126 0.0763 0.0804
Trypanosoma cruzi cdc2-related kinase 1 0.0126 0.0768 0.1453
Schistosoma mansoni tyrosine kinase 0.01 0.0493 0.0849
Entamoeba histolytica protein kinase, putative 0.0094 0.043 0.0819
Schistosoma mansoni nck2/grb4 0.0109 0.0589 0.1015
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0207 0.1613 0.1707
Schistosoma mansoni tyrosine kinase 0.0382 0.3453 0.5944
Trypanosoma cruzi cdc2-related kinase 1 0.0126 0.0768 0.1453
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0356 0.3179 0.3834
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0222 0.1771 0.2136
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0065 0.0128 0.0154
Plasmodium vivax protein kinase Crk2 0.0126 0.0768 0.1453
Echinococcus granulosus tyrosine protein kinase Fyn 0.0276 0.2336 0.2336
Brugia malayi Protein kinase domain containing protein 0.0952 0.9423 1
Plasmodium falciparum cGMP-dependent protein kinase 0.0142 0.0931 0.1763
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0269 0.2268 0.2402
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.1268 0.2413
Loa Loa (eye worm) hypothetical protein 0.014 0.0912 0.0962
Echinococcus multilocularis dual specificity 0.0217 0.1724 0.208
Schistosoma mansoni serine/threonine protein kinase 0.0267 0.2244 0.3862
Trichomonas vaginalis STE family protein kinase 0.0094 0.043 0.0818
Trypanosoma cruzi casein kinase, putative 0.0116 0.0664 0.1254
Entamoeba histolytica protein kinase, putative 0.0091 0.04 0.0762
Schistosoma mansoni serine/threonine protein kinase 0.0217 0.1724 0.2968
Toxoplasma gondii AGC kinase 0.012 0.0709 0.1339
Trichomonas vaginalis AGC family protein kinase 0.0332 0.2924 0.5566
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.012 0.0709 0.0746
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0222 0.1771 0.1771
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0143 0.0947 0.1794
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0126 0.0768 0.081
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0089 0.0379 0.071
Echinococcus granulosus titin 0.008 0.0285 0.0285
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0554 0.5253 1
Schistosoma mansoni serine/threonine protein kinase 0.016 0.1128 0.1941
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0066 0.0133 0.0133
Echinococcus multilocularis mitogen activated protein kinase 14 0.029 0.2485 0.2997
Trypanosoma brucei aurora B kinase 0.0554 0.5253 1
Brugia malayi Doublecortin family protein 0.0158 0.1099 0.116
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0155 0.1076 0.1136
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0063 0.0107 0.0203
Trypanosoma brucei rac serine-threonine kinase, putative 0.0332 0.2924 0.5561
Trichomonas vaginalis CMGC family protein kinase 0.0126 0.0768 0.1462
Toxoplasma gondii NEK kinase 0.0059 0.0066 0.0115
Schistosoma mansoni hypothetical protein 0.0448 0.4143 0.7131
Loa Loa (eye worm) hypothetical protein 0.0176 0.1287 0.136
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0163 0.1158 0.2196
Plasmodium falciparum serine/threonine protein kinase 0.0091 0.04 0.0751
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0092 0.0407 0.0764
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0122 0.0721 0.087
Schistosoma mansoni protein kinase 0.0345 0.3065 0.5276
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0496 0.4641 0.5598
Giardia lamblia Kinase, CAMK CAMKL 0.0105 0.0547 0.0926
Schistosoma mansoni serine/threonine-protein kinase 0.0172 0.1251 0.2153
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0275 0.233 0.233
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.087 0.1656
Echinococcus multilocularis protein tyrosine kinase 0.03 0.2593 0.3128
Echinococcus multilocularis roundabout 2 0.0151 0.1024 0.1235
Onchocerca volvulus 0.0065 0.0128 0.01
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.029 0.2485 0.4724
Plasmodium falciparum calcium-dependent protein kinase 5 0.0146 0.0972 0.1841
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Schistosoma mansoni tensin 0.0065 0.0128 0.022
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0094 0.043 0.043
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.029 0.2485 0.2633
Brugia malayi Protein kinase domain containing protein 0.0223 0.1781 0.1884
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0085 0.0338 0.0633
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.012 0.0709 0.0709
Brugia malayi Protein kinase domain containing protein 0.0599 0.573 0.6078
Schistosoma mansoni nephrin 0.0059 0.0067 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0284 0.2424 0.4173
Trichomonas vaginalis CAMK family protein kinase 0.0283 0.2412 0.459
Brugia malayi diacylglycerol kinase 0.0061 0.0081 0.008
Loa Loa (eye worm) TK/FER protein kinase 0.0116 0.0665 0.07
Echinococcus multilocularis death associated protein kinase 1 0.0844 0.829 1
Echinococcus multilocularis Zinc finger, DBF type 0.0448 0.4143 0.4997
Trichomonas vaginalis AGC family protein kinase 0.0554 0.5253 1
Entamoeba histolytica protein kinase, putative 0.0323 0.2832 0.5391
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0155 0.1076 0.1076
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0053 0.0006 0.001
Schistosoma mansoni tyrosine kinase 0.0447 0.4133 0.7115
Echinococcus multilocularis serine threonine protein kinase 0.0323 0.2835 0.342
Giardia lamblia Kinase, AGC PKA 0.012 0.0709 0.1239
Echinococcus multilocularis casein kinase I alpha 0.0116 0.0664 0.0801
Echinococcus granulosus epidermal growth factor receptor 0.0607 0.5809 0.5809
Loa Loa (eye worm) hypothetical protein 0.0163 0.1158 0.1223
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Echinococcus multilocularis protein KINase family member (kin 25) 0.0114 0.0643 0.0775
Echinococcus granulosus tyrosine protein kinase ABL1 0.032 0.2804 0.2804
Echinococcus granulosus epidermal growth factor receptor 0.0402 0.3663 0.3663
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0006 0.001
Echinococcus granulosus serine:threonine kinase SAD 1 0.0097 0.0465 0.0465
Echinococcus multilocularis cyclin dependent kinase 19 0.0171 0.1235 0.149
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0262 0.2192 0.2321
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0199 0.1531 0.162
Trichomonas vaginalis CMGC family protein kinase 0.0136 0.087 0.1656
Echinococcus multilocularis dual specificity mitogen activated protein 0.0188 0.1413 0.1704
Echinococcus granulosus casein kinase I delta 0.0116 0.0664 0.0664
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0142 0.0931 0.1123
Echinococcus multilocularis casein kinase I delta 0.0116 0.0664 0.0801
Brugia malayi Tyrosine-protein kinase abl-1 0.0126 0.0767 0.0808
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0063 0.0107 0.0107
Echinococcus granulosus activated cdc42 kinase 1 0.0215 0.1695 0.1695
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0146 0.0972 0.1026
Echinococcus multilocularis dual specificity protein kinase clk2 0.016 0.1128 0.136
Onchocerca volvulus 0.0116 0.0665 0.0673
Entamoeba histolytica diacylglycerol kinase, putative 0.0061 0.0081 0.0154
Leishmania major protein kinase, putative 0.0093 0.0421 0.0791
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0171 0.1235 0.1235
Schistosoma mansoni tyrosine kinase 0.0536 0.5068 0.8724
Schistosoma mansoni serine/threonine protein kinase 0.0171 0.1235 0.2126
Echinococcus granulosus Rac GTPase activating protein 1 0.0061 0.0082 0.0082
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0097 0.0465 0.0875
Echinococcus granulosus Glutaredoxin protein 5 0.0122 0.0721 0.0721
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0102 0.0515 0.054
Brugia malayi Tyrosine-protein kinase abl-1 0.0238 0.1945 0.2059
Loa Loa (eye worm) hypothetical protein 0.0081 0.0296 0.0308
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0094 0.043 0.043
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0126 0.0763 0.0804
Echinococcus multilocularis mitogen activated protein kinase 3 0.0092 0.0407 0.0491
Echinococcus multilocularis epidermal growth factor receptor 0.0402 0.3663 0.4418
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0092 0.0407 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.0192 0.1459 0.2512
Echinococcus granulosus protein kinase c epsilon type 0.0267 0.2244 0.2244
Schistosoma mansoni unc-13 (munc13) 0.0066 0.0133 0.0229
Echinococcus granulosus Vam6:Vps39 protein 0.0085 0.0338 0.0338
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0275 0.233 0.2468
Brugia malayi Protein kinase domain containing protein 0.0116 0.0665 0.07
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0059 0.0067 0.0065
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0116 0.0664 0.0699
Trichomonas vaginalis AGC family protein kinase 0.0332 0.2924 0.5566
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.1557 0.268
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0414 0.3786 0.4566
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0209 0.1633 0.1727
Echinococcus multilocularis rho associated protein kinase 0.0329 0.2896 0.3493
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0146 0.0972 0.0972
Echinococcus granulosus casein kinase I alpha 0.0116 0.0664 0.0664
Trypanosoma brucei Serine/threonine-protein kinase NEK11, putative 0.0059 0.0066 0.0115
Schistosoma mansoni protein kinase 0.0246 0.2024 0.3484
Loa Loa (eye worm) hypothetical protein 0.0236 0.1918 0.2031
Echinococcus multilocularis serine:threonine protein kinase N2 0.0329 0.2894 0.349
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0276 0.2336 0.2818
Brugia malayi protein kinase C3,putative 0.0184 0.1373 0.1452
Brugia malayi Cam kinase protein 1 0.0146 0.0972 0.1026
Brugia malayi Protein kinase domain containing protein 0.0557 0.5286 0.5607
Loa Loa (eye worm) hypothetical protein 0.0074 0.022 0.0227
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0554 0.5253 0.5253
Echinococcus multilocularis transfer RNA-Thr 0.0215 0.1695 0.2045
Echinococcus multilocularis cyclin dependent kinase 5 0.0126 0.0768 0.0927
Onchocerca volvulus Cell death protein 3 homolog 0.0103 0.0528 0.0526
Toxoplasma gondii diacylglycerol kinase, putative 0.0061 0.0081 0.0143
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.1771 0.3048
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0163 0.1158 0.1397
Loa Loa (eye worm) STAT protein 0.0065 0.0128 0.0129
Echinococcus multilocularis epidermal growth factor receptor 0.0607 0.5809 0.7007
Loa Loa (eye worm) CAMK protein kinase 0.008 0.0285 0.0296
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0126 0.0763 0.0921
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.0774
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0085 0.0338 0.0633
Echinococcus granulosus SH2 domain containing protein 7 0.0065 0.0128 0.0128
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Trypanosoma cruzi casein kinase, putative 0.0116 0.0664 0.1254
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Echinococcus multilocularis Immunoglobulin 0.0091 0.0403 0.0486
Echinococcus granulosus caspase 8 0.0053 0.0006 0.0006
Onchocerca volvulus 0.0065 0.0128 0.01
Echinococcus multilocularis 0.0065 0.0128 0.0154
Trichomonas vaginalis AGC family protein kinase 0.0332 0.2924 0.5566
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0934 0.1607
Echinococcus granulosus serine:threonine protein kinase 0.0122 0.072 0.072
Schistosoma mansoni signal transduction protein lnk-related 0.0065 0.0128 0.022
Echinococcus granulosus SH2 motif 0.0065 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0103 0.0528 0.0554
Loa Loa (eye worm) hypothetical protein 0.0112 0.0623 0.0655
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0146 0.0972 0.1172
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0217 0.1724 0.1825
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.012 0.0709 0.1339
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.012 0.0709 0.1339
Echinococcus granulosus beta-adrenergic receptor kinase 0.0054 0.0016 0.0016
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0136 0.087 0.105
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0089 0.0379 0.071
Echinococcus granulosus protein kinase C gamma type 0.0323 0.2835 0.2835
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0136 0.087 0.1647
Trypanosoma brucei protein kinase, putative 0.0136 0.087 0.1647
Schistosoma mansoni tyrosine kinase 0.0351 0.3125 0.538
Onchocerca volvulus 0.0116 0.0665 0.0673
Echinococcus multilocularis TGF beta receptor type 1 0.0112 0.0623 0.0752
Entamoeba histolytica protein kinase, putative 0.0073 0.0207 0.0393
Trichomonas vaginalis AGC family protein kinase 0.0554 0.5253 1
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Trypanosoma brucei SNF1-related protein kinases, putative 0.0097 0.0465 0.0875
Loa Loa (eye worm) hypothetical protein 0.0363 0.3256 0.3451
Brugia malayi Protein kinase domain containing protein 0.0207 0.1613 0.1707
Echinococcus granulosus calcium dependent protein kinase 0.0104 0.0535 0.0535
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0092 0.0407 0.0764
Brugia malayi Protein kinase domain containing protein 0.0217 0.1724 0.1825
Schistosoma mansoni serine/threonine protein kinase 0.0397 0.3608 0.621
Echinococcus multilocularis caspase 3 0.0088 0.0367 0.0442
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.012 0.0709 0.1339
Entamoeba histolytica protein kinase, putative 0.0332 0.2924 0.5566
Echinococcus granulosus suppressor of cytokine signaling 6 0.0065 0.0128 0.0128
Trypanosoma cruzi Serine/threonine-protein kinase NEK11, putative 0.0059 0.0066 0.0115
Entamoeba histolytica PH domain containing protein kinase, putative 0.0129 0.0801 0.1525
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0006 0.001
Entamoeba histolytica hypothetical protein 0.0217 0.1724 0.3282
Brugia malayi probable protein kinase 0.0186 0.1395 0.1475
Loa Loa (eye worm) TK protein kinase 0.0274 0.2317 0.2454
Brugia malayi Protein kinase domain containing protein 0.0199 0.1531 0.162
Loa Loa (eye worm) hypothetical protein 0.0102 0.0514 0.054
Trichomonas vaginalis CMGC family protein kinase 0.0126 0.0768 0.1462
Echinococcus multilocularis tyrosine protein kinase shark 0.0536 0.5068 0.6113
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0093 0.0421 0.0791
Onchocerca volvulus 0.0066 0.0133 0.0106
Schistosoma mansoni hypothetical protein 0.01 0.0497 0.0855
Brugia malayi Protein kinase domain containing protein 0.007 0.0181 0.0186
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0059 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Entamoeba histolytica protein kinase, putative 0.0079 0.0274 0.0521
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0345 0.3065 0.3065
Loa Loa (eye worm) hypothetical protein 0.01 0.0497 0.0521
Echinococcus granulosus tyrosine protein kinase Src42A 0.0276 0.2336 0.2336
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0323 0.2832 0.3001
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0061 0.0081 0.008
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0146 0.0972 0.1841
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.012 0.0709 0.1339
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0065 0.0128 0.0129
Echinococcus multilocularis nervana 2 0.0122 0.0721 0.087
Brugia malayi Protein kinase domain containing protein 0.0221 0.1768 0.1871
Loa Loa (eye worm) hypothetical protein 0.0117 0.0673 0.0708
Loa Loa (eye worm) hypothetical protein 0.0059 0.0067 0.0065
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Echinococcus granulosus tyrosine protein kinase Blk 0.0232 0.1875 0.1875
Loa Loa (eye worm) hypothetical protein 0.014 0.0912 0.0962
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0065 0.0128 0.0129
Brugia malayi Egg laying defective protein 4 0.0142 0.0931 0.0983
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0079 0.0272 0.0328
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0201 0.1557 0.1878
Loa Loa (eye worm) AUR protein kinase 0.0554 0.5253 0.5572
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0931 0.1603
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.04 0.0689
Loa Loa (eye worm) hypothetical protein 0.0081 0.0296 0.0308
Schistosoma mansoni serine/threonine protein kinase 0.0384 0.347 0.5974
Brugia malayi RhoGAP domain containing protein 0.0126 0.0763 0.0804
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0284 0.2424 0.2924
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0284 0.2424 0.2568
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Onchocerca volvulus 0.0065 0.0128 0.01
Echinococcus granulosus TGF-beta receptor type-1 0.0112 0.0623 0.0623
Onchocerca volvulus 0.0136 0.087 0.0891
Schistosoma mansoni protein kinase 0.0073 0.0207 0.0356
Brugia malayi serine/threonine-protein kinase 6 0.0554 0.5253 0.5572
Loa Loa (eye worm) hypothetical protein 0.0056 0.0028 0.0023
Schistosoma mansoni tyrosine kinase 0.03 0.2593 0.4463
Plasmodium vivax serine/threonine kinase-1, putative 0.016 0.1128 0.2137
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0243 0.1991 0.2108
Loa Loa (eye worm) CMGC/CLK protein kinase 0.016 0.1128 0.1191
Echinococcus multilocularis tyrosine protein kinase ABL1 0.032 0.2804 0.3382
Echinococcus granulosus TGF beta receptor type 1 0.0112 0.0623 0.0623
Schistosoma mansoni protein kinase 0.0246 0.2024 0.3484
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0065 0.0128 0.0154
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.029 0.2485 0.4724
Echinococcus granulosus dual specificity protein kinase clk2 0.016 0.1128 0.1128
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0709 0.122
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0061 0.0082 0.008
Echinococcus granulosus N chimaerin 0.0126 0.0763 0.0763
Echinococcus granulosus Zinc finger DBF type 0.0098 0.0472 0.0472
Loa Loa (eye worm) hypothetical protein 0.012 0.0709 0.0746
Toxoplasma gondii NEK kinase 0.0059 0.0066 0.0115
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0397 0.3608 0.3825
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.1633 0.281
Schistosoma mansoni serine/threonine protein kinase 0.026 0.2173 0.374
Trypanosoma cruzi casein kinase, putative 0.0116 0.0664 0.1254
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0152 0.1037 0.1251
Schistosoma mansoni GTPase activating protein 0.0065 0.0128 0.0221
Echinococcus multilocularis beta adrenergic receptor kinase 0.0054 0.0016 0.0019
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0188 0.1413 0.1494
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Schistosoma mansoni protein kinase 0.0554 0.5253 0.9043
Loa Loa (eye worm) hypothetical protein 0.0129 0.0801 0.0845
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0972 0.1673
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0066 0.0125
Giardia lamblia Kinase, CMGC GSK 0.0136 0.087 0.155
Schistosoma mansoni diacylglycerol kinase theta 0.0061 0.0081 0.0139
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0091 0.0403 0.0486
Schistosoma mansoni unc-13 (munc13) 0.0066 0.0133 0.0229
Trypanosoma cruzi cdc2-related kinase 3 0.0126 0.0768 0.1453
Brugia malayi STAT protein, DNA binding domain containing protein 0.0065 0.0128 0.0129
Brugia malayi serine/threonine protein kinase 6 0.0554 0.5253 0.5572
Plasmodium falciparum casein kinase 2, alpha subunit 0.0174 0.1268 0.2405
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0232 0.1875 0.2261
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.012 0.0709 0.1339
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Brugia malayi Protein kinase domain containing protein 0.016 0.1128 0.1191
Loa Loa (eye worm) hypothetical protein 0.0122 0.072 0.0758
Loa Loa (eye worm) AUR protein kinase 0.0554 0.5253 0.5572
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.012 0.0709 0.0855
Schistosoma mansoni protein kinase 0.0199 0.1531 0.2636
Schistosoma mansoni hypothetical protein 0.01 0.0497 0.0855
Brugia malayi Immunoglobulin I-set domain containing protein 0.0102 0.0514 0.054
Loa Loa (eye worm) hypothetical protein 0.014 0.0919 0.0969
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.012 0.0709 0.1339
Trichomonas vaginalis CAMK family protein kinase 0.0146 0.0972 0.185
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0201 0.1557 0.1878
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0016 0.0027
Brugia malayi bone morphogenetic protein type 1 receptor 0.0122 0.0724 0.0762
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0006 0.001
Echinococcus granulosus tyrosine protein kinase Srms 0.0517 0.4869 0.4869
Echinococcus granulosus serine/threonine protein kinase 0.0172 0.1251 0.1251
Onchocerca volvulus 0.0074 0.0227 0.0205
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0122 0.072 0.0758
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0079 0.0274 0.0274
Brugia malayi Furin-like cysteine rich region family protein 0.0607 0.5809 0.6163
Echinococcus multilocularis protein kinase c epsilon type 0.0267 0.2244 0.2706
Loa Loa (eye worm) thyroid receptor interactor 0.0119 0.069 0.0727
Echinococcus multilocularis PAK box P21 Rho binding 0.0073 0.0207 0.0249
Trichomonas vaginalis AGC family protein kinase 0.0209 0.1638 0.3118
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0091 0.04 0.0751
Trichomonas vaginalis CMGC family protein kinase 0.016 0.1128 0.2146
Echinococcus granulosus roundabout 2 0.0151 0.1024 0.1024
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0155 0.1076 0.1136
Schistosoma mansoni protein kinase 0.0582 0.5551 0.9555
Loa Loa (eye worm) casein kinase 0.0177 0.1305 0.1379
Echinococcus multilocularis dual specificity 0.0146 0.0976 0.1178
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0141 0.0927 0.0927
Loa Loa (eye worm) TK/FAK protein kinase 0.0303 0.2624 0.278
Echinococcus granulosus dual specificity 0.0146 0.0976 0.0976
Brugia malayi Hr1 repeat family protein 0.0329 0.2894 0.3067
Entamoeba histolytica diacylglycerol kinase, putative 0.0061 0.0081 0.0154
Loa Loa (eye worm) hypothetical protein 0.0102 0.0514 0.054
Entamoeba histolytica protein kinase, putative 0.0053 0.0004 0.0007
Loa Loa (eye worm) gastrulation defective protein 1 0.0129 0.0798 0.0841
Loa Loa (eye worm) TK/FER protein kinase 0.0116 0.0665 0.07
Onchocerca volvulus 0.0123 0.0733 0.0745
Trichomonas vaginalis CMGC family protein kinase 0.0126 0.0768 0.1462
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Loa Loa (eye worm) TK/FER protein kinase 0.0116 0.0665 0.07
Echinococcus multilocularis tyrosine protein kinase Blk 0.0232 0.1875 0.2261
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.012 0.0709 0.1339
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.012 0.0709 0.0855
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0079 0.0272 0.0282
Echinococcus granulosus cGMP dependent protein kinase 1 0.0142 0.0931 0.0931
Echinococcus granulosus protein kinase c iota type 0.0343 0.3046 0.3046
Leishmania major casein kinase II, putative 0.0174 0.1268 0.2405
Schistosoma mansoni protein kinase 0.0582 0.5551 0.9555
Trypanosoma brucei cdc2-related kinase 3 0.0126 0.0768 0.1453
Schistosoma mansoni cell adhesion molecule 0.0123 0.0735 0.1265
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0093 0.0416 0.0793
Entamoeba histolytica casein kinase 1, putative 0.0116 0.0664 0.1264
Schistosoma mansoni protein kinase 0.0582 0.5551 0.9555
Brugia malayi protein unc-22 0.008 0.0285 0.0296
Entamoeba histolytica protein kinase, putative 0.0151 0.1024 0.1949
Echinococcus granulosus NCK adaptor protein 0.0109 0.0589 0.0589
Plasmodium falciparum protein serine/threonine kinase-1 0.016 0.1128 0.2137
Plasmodium vivax protein kinase, putative 0.0066 0.0139 0.0254
Schistosoma mansoni protein kinase 0.0094 0.043 0.0741
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0217 0.1724 0.3275
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0146 0.0972 0.1841
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.016 0.1128 0.2137
Echinococcus multilocularis serine:threonine protein kinase 0.0122 0.072 0.0869
Brugia malayi Cell death protein 3 precursor 0.0103 0.0528 0.0554
Onchocerca volvulus 0.0478 0.4454 0.4708
Loa Loa (eye worm) hypothetical protein 0.0056 0.0028 0.0023
Echinococcus granulosus hypothetical protein 0.0119 0.069 0.069
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0619 0.1065
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0163 0.1158 0.2196
Brugia malayi Protein kinase domain containing protein 0.0219 0.1742 0.1844
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0146 0.0972 0.0972
Brugia malayi protein-tyrosine kinase 0.0232 0.1875 0.1984
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0065 0.0128 0.0154
Leishmania major casein kinase, putative 0.0116 0.0664 0.1254
Trypanosoma cruzi aurora B kinase, putative 0.0554 0.5253 1
Echinococcus multilocularis SH2 motif 0.0065 0.0128 0.0154
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0465 0.0886
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.1557 0.268
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.0774
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0065 0.0128 0.01
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0141 0.0927 0.1118
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0126 0.0768 0.081
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0345 0.3065 0.3248
Toxoplasma gondii aurora kinase 0.0554 0.5253 1
Schistosoma mansoni atypical protein kinase C 0.0349 0.3109 0.5352
Onchocerca volvulus 0.0273 0.2308 0.2422
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0376 0.3387 0.359
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0123 0.0125
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0006 0.001
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0235 0.191 0.2304
Leishmania major protein kinase, putative 0.016 0.1128 0.2137
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0163 0.1158 0.2196
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0188 0.1413 0.2681
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0458 0.4245 0.512
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0063 0.0107 0.0107
Echinococcus granulosus mitogen activated protein kinase 14 0.029 0.2485 0.2485
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0345 0.3065 0.3697
Brugia malayi putative serine/threonine kinase SADA gamma 0.0097 0.0465 0.0488
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Entamoeba histolytica protein kinase domain containing protein 0.0217 0.1724 0.3282
Loa Loa (eye worm) hypothetical protein 0.006 0.0077 0.0076
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0136 0.087 0.087
Trypanosoma cruzi casein kinase II, putative 0.0174 0.1268 0.2405
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0384 0.0729
Trichomonas vaginalis CAMK family protein kinase 0.0275 0.233 0.4435
Entamoeba histolytica protein kinase, putative 0.0081 0.0299 0.0569
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0117 0.0673 0.0811
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0094 0.043 0.0519
Brugia malayi Protein kinase domain containing protein 0.0116 0.0665 0.07
Brugia malayi Protein kinase domain containing protein 0.0171 0.1235 0.1305
Brugia malayi hypothetical protein 0.0065 0.0128 0.0129
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0097 0.0465 0.0875
Trichomonas vaginalis CAMK family protein kinase 0.0275 0.233 0.4435
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0174 0.1268 0.2405
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.012 0.0709 0.0709
Schistosoma mansoni tyrosine kinase 0.0276 0.2336 0.4022
Entamoeba histolytica protein kinase domain containing protein 0.0136 0.087 0.1656
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0246 0.2024 0.2441
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Plasmodium vivax tyrosine kinase-like protein, putative 0.0089 0.0379 0.071
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0677 0.1165
Echinococcus granulosus roundabout 2 0.0059 0.0067 0.0067
Leishmania major protein kinase, putative 0.016 0.1128 0.2137
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0133 0.0843 0.1595
Onchocerca volvulus Serine\/threonine kinase homolog 0.0171 0.1235 0.128
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0085 0.0338 0.0633
Brugia malayi Protein kinase domain containing protein 0.0356 0.3179 0.3369
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0122 0.073 0.0881
Plasmodium falciparum NIMA related kinase 4 0.0059 0.0066 0.0115
Echinococcus multilocularis serine:threonine protein kinase NIM1 0.0123 0.0733 0.0885
Schistosoma mansoni tyrosine kinase 0.0351 0.3125 0.538
Echinococcus granulosus tensin 0.0065 0.0128 0.0128
Echinococcus granulosus caspase 3 0.0088 0.0367 0.0367
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0092 0.0407 0.0764
Loa Loa (eye worm) hypothetical protein 0.0085 0.0338 0.0353
Loa Loa (eye worm) AUR protein kinase 0.0554 0.5253 0.5572
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0126 0.0763 0.0763
Schistosoma mansoni diacylglycerol kinase theta 0.0061 0.0081 0.0139
Entamoeba histolytica protein kinase, putative 0.0146 0.0972 0.185
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0093 0.0421 0.0791
Giardia lamblia Kinase, CK1 Casein kinase 0.0116 0.0664 0.1152
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.008 0.0285 0.0296
Echinococcus multilocularis tensin 0.0065 0.0128 0.0154
Echinococcus multilocularis myosin iiia 0.0093 0.0416 0.0502
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0093 0.0416 0.0782
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0066 0.0133 0.016
Echinococcus multilocularis roundabout 2 0.0059 0.0067 0.0081
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0192 0.1459 0.1543
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0458 0.4245 0.4245
Schistosoma mansoni protein kinase C 0.0066 0.0133 0.0229
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0184 0.1374 0.1657
Entamoeba histolytica protein kinase, putative 0.0167 0.1193 0.2271
Toxoplasma gondii AGC kinase 0.012 0.0709 0.1339
Onchocerca volvulus 0.0098 0.0469 0.0464
Schistosoma mansoni ephrin receptor 0.0062 0.0095 0.0164
Entamoeba histolytica protein kinase, putative 0.0107 0.0565 0.1075
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0069 0.0172 0.0296
Loa Loa (eye worm) AGC/PKA protein kinase 0.012 0.0709 0.0746
Echinococcus granulosus twitchin 0.0161 0.1129 0.1129
Onchocerca volvulus 0.0116 0.0665 0.0673
Loa Loa (eye worm) TK/FER protein kinase 0.0116 0.0665 0.07
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.1268 0.2413
Schistosoma mansoni suppressor of cytokine signaling 0.0065 0.0128 0.022
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0733 0.1262
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0976 0.1858
Leishmania major protein kinase A catalytic subunit isoform 1 0.012 0.0709 0.1339
Echinococcus granulosus protein kinase shaggy 0.0136 0.087 0.087
Schistosoma mansoni growth factor receptor-bound protein 0.0113 0.0626 0.1078
Echinococcus multilocularis casein kinase i 0.0116 0.0664 0.0801
Loa Loa (eye worm) hypothetical protein 0.0063 0.0106 0.0106
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0109 0.0589 0.062
Brugia malayi Casein kinase II, alpha chain 0.0174 0.1268 0.134
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0677 0.1165
Echinococcus granulosus cGMP dependent protein kinase 0.0142 0.0931 0.0931
Echinococcus multilocularis active breakpoint cluster region 0.0103 0.053 0.064
Loa Loa (eye worm) hypothetical protein 0.0061 0.0081 0.008
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0079 0.0272 0.0272
Trypanosoma brucei NIMA-related protein kinase 0.0059 0.0066 0.0115
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0582 0.5551 0.5551
Brugia malayi Protein kinase domain containing protein 0.0122 0.072 0.0758
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0071 0.0186 0.0354
Loa Loa (eye worm) TK/FER protein kinase 0.0116 0.0665 0.07
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0006 0.001
Echinococcus granulosus cyclin dependent kinase 9 0.0086 0.0348 0.0348
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0155 0.1076 0.1136
Toxoplasma gondii histone kinase SNF1, putative 0.0097 0.0465 0.0875
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0276 0.2336 0.2818
Schistosoma mansoni serine/threonine protein kinase 0.0414 0.3786 0.6517
Loa Loa (eye worm) SH2 domain-containing protein 0.0065 0.0128 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0173 0.0297
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0192 0.1459 0.176
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.016 0.1128 0.2137
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0146 0.0972 0.1026
Schistosoma mansoni protein kinase 0.0174 0.1268 0.2183
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0171 0.1235 0.1305
Loa Loa (eye worm) hypothetical protein 0.0085 0.0338 0.0353
Echinococcus granulosus raf serine:threonine protein kinase 0.0112 0.0619 0.0619
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0599 0.573 0.6078
Onchocerca volvulus 0.0065 0.0128 0.01
Giardia lamblia Kinase, CMGC CDK 0.0126 0.0768 0.1353
Loa Loa (eye worm) AGC/NDR protein kinase 0.0201 0.1557 0.1647
Trichomonas vaginalis STE family protein kinase 0.0188 0.1413 0.2689
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0066 0.0125
Schistosoma mansoni tyrosine kinase 0.0471 0.4386 0.7551
Plasmodium falciparum serine/threonine protein kinase, putative 0.0554 0.5253 1
Brugia malayi SH2 domain containing protein 0.0065 0.0128 0.0129
Echinococcus multilocularis ephrin type A receptor 4 A 0.0114 0.0644 0.0776
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0055 0.0021 0.0021
Giardia lamblia Kinase, CMGC CDK 0.0126 0.0768 0.1353
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Entamoeba histolytica casein kinase, putative 0.0116 0.0664 0.1264
Entamoeba histolytica protein kinase, putative 0.0217 0.1724 0.3282
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0074 0.0227 0.042
Schistosoma mansoni hypothetical protein 0.0065 0.0128 0.022
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0146 0.0976 0.1849
Schistosoma mansoni nephrin 0.013 0.0804 0.1384
Brugia malayi intracellular kinase 0.0136 0.087 0.0918
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0099 0.0488 0.0589
Echinococcus multilocularis mitogen activated protein kinase 14 0.029 0.2485 0.2997
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.01 0.0489 0.0489
Echinococcus granulosus SHC transforming protein 3 0.0065 0.0128 0.0128
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0217 0.1724 0.3275
Entamoeba histolytica SH2 domain containing protein 0.0065 0.0128 0.0243
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0192 0.1459 0.1543
Echinococcus granulosus NDR protein kinase 0.0201 0.1557 0.1557
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0065 0.0128 0.0154
Echinococcus granulosus aurora kinase A 0.0554 0.5253 0.5253
Leishmania major protein kinase A catalytic subunit isoform 2 0.012 0.0709 0.1339
Schistosoma mansoni cell adhesion molecule 0.0059 0.0067 0.0116
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0182 0.1356 0.1434
Brugia malayi MAP kinase sur-1 0.0092 0.0407 0.0426
Schistosoma mansoni serine/threonine protein kinase 0.016 0.1128 0.1941
Echinococcus multilocularis serine:threonine protein kinase N2 0.0201 0.1557 0.1878
Echinococcus multilocularis serine:threonine protein kinase 0.0122 0.072 0.0869
Entamoeba histolytica protein kinase, putative 0.0091 0.04 0.0762
Trichomonas vaginalis STE family protein kinase 0.0059 0.0066 0.0125
Brugia malayi hypothetical protein 0.0414 0.3786 0.4014
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0146 0.0972 0.1841
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0188 0.1413 0.1494
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0269 0.2268 0.2736
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.016 0.1128 0.2137
Toxoplasma gondii casein kinase I 0.0116 0.0664 0.1254
Onchocerca volvulus 0.0098 0.0469 0.0464
Schistosoma mansoni tensin 0.0065 0.0128 0.022
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0496 0.4641 0.4641
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0146 0.0972 0.0972
Brugia malayi RhoGEF domain containing protein 0.0061 0.0082 0.008
Schistosoma mansoni tyrosine kinase 0.0276 0.2336 0.4022
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.2896 0.4985
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.0356 0.3179 0.5472
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0093 0.0416 0.0793
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.0768 0.1323
Loa Loa (eye worm) TK/EGFR protein kinase 0.0607 0.5809 0.6163
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0144 0.0958 0.0958
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0201 0.1557 0.1557
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.0774
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0136 0.087 0.0918
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0091 0.04 0.0751
Echinococcus granulosus serine:threonine protein kinase N2 0.0128 0.0783 0.0783
Brugia malayi protein kinase C II. 0.0267 0.2244 0.2376
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0097 0.0465 0.0875
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Echinococcus granulosus activin receptor type 0.0454 0.4201 0.4201
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Schistosoma mansoni caspase-7 (C14 family) 0.0141 0.0927 0.1595
Loa Loa (eye worm) hypothetical protein 0.0061 0.0082 0.008
Plasmodium falciparum serine/threonine protein kinase KIN 0.0097 0.0465 0.0875
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0097 0.0465 0.0488
Loa Loa (eye worm) hypothetical protein 0.0599 0.573 0.6078
Echinococcus granulosus neuroglian 0.0119 0.0692 0.0692
Echinococcus multilocularis Immunoglobulin 0.0091 0.0403 0.0486
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0122 0.0724 0.0762
Loa Loa (eye worm) TK/FER protein kinase 0.0415 0.3793 0.4022
Giardia lamblia Kinase, CMGC SRPK 0.0091 0.04 0.0644
Echinococcus multilocularis activated cdc42 kinase 1 0.0215 0.1695 0.2045
Echinococcus granulosus serine:threonine protein kinase NIM1 0.0123 0.0733 0.0733
Onchocerca volvulus 0.0201 0.1554 0.1619
Loa Loa (eye worm) AGC/PKG protein kinase 0.0142 0.0931 0.0983
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0976 0.1858
Schistosoma mansoni tyrosine kinase 0.0246 0.2028 0.3491
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0465 0.0801
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0097 0.0465 0.0488
Loa Loa (eye worm) hypothetical protein 0.0478 0.4454 0.4724
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0085 0.0338 0.0582
Mycobacterium ulcerans hypothetical protein 0.01 0.0494 1
Onchocerca volvulus 0.008 0.0285 0.0267
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0143 0.0947 0.1794
Brugia malayi Protein kinase domain containing protein 0.0099 0.0488 0.0512
Loa Loa (eye worm) hypothetical protein 0.0092 0.0407 0.0425
Echinococcus multilocularis SH2 domain containing protein 7 0.0065 0.0128 0.0154
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0065 0.0128 0.01
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0415 0.3793 0.3793
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0276 0.2336 0.2336
Leishmania major protein kinase, putative 0.0146 0.0972 0.1841
Schistosoma mansoni tyrosine kinase 0.0402 0.3663 0.6305
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0222 0.1771 0.2136
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0117 0.0677 0.0713
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0174 0.1268 0.134
Giardia lamblia Kinase, PLK 0.0275 0.233 0.4364
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0146 0.0972 0.1841
Echinococcus multilocularis rac serine:threonine kinase 0.0172 0.1251 0.1508
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Brugia malayi cytokine inducible SH2-containing protein 5 0.0065 0.0128 0.0129
Echinococcus granulosus nervana 2 0.0122 0.0721 0.0721
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0402 0.3663 0.3663
Schistosoma mansoni protein kinase 0.0101 0.0503 0.0866
Echinococcus granulosus myotubularin protein 13 0.0069 0.0173 0.0173
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Trichomonas vaginalis STE family protein kinase 0.0188 0.1413 0.2689
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0065 0.0128 0.022
Schistosoma mansoni serine/threonine protein kinase 0.0079 0.0274 0.0472
Loa Loa (eye worm) TK protein kinase 0.0167 0.1193 0.126
Brugia malayi SH2 domain containing protein 0.0065 0.0128 0.0129
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0116 0.0664 0.0699
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0065 0.0128 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.0847 0.1611
Loa Loa (eye worm) TK protein kinase 0.035 0.3112 0.3298
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.1268 0.2413
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Brugia malayi serine/threonine-protein kinase plk-2 0.0275 0.233 0.2468
Echinococcus multilocularis caspase 0.0141 0.0927 0.1118
Giardia lamblia Aurora kinase 0.0554 0.5253 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.0665 0.07
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0246 0.2028 0.2446
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0276 0.2336 0.2818
Plasmodium falciparum protein kinase, putative 0.0093 0.0421 0.0791
Onchocerca volvulus Tyrosine kinase homolog 0.0557 0.5281 0.5589
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0469 0.0892
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0126 0.0768 0.081
Loa Loa (eye worm) hypothetical protein 0.0084 0.0331 0.0345
Echinococcus multilocularis casein kinase I alpha 0.0116 0.0664 0.0801
Loa Loa (eye worm) SH2 domain-containing protein 0.0065 0.0128 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0006 0.001
Brugia malayi Protein kinase domain containing protein 0.0447 0.4133 0.4383
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0423 0.3878 0.4677
Brugia malayi tRNA modification GTPase TrmE family protein 0.0065 0.0128 0.0129
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0209 0.1633 0.1969
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0093 0.0421 0.0791
Brugia malayi p70 ribosomal S6 kinase beta 0.0323 0.2832 0.3001
Loa Loa (eye worm) hypothetical protein 0.0061 0.0081 0.008
Echinococcus granulosus cyclin dependent kinase 0.0126 0.0768 0.0768
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.2894 0.4981
Loa Loa (eye worm) TK/ABL protein kinase 0.032 0.2804 0.2971
Brugia malayi SH2 domain containing protein 0.0065 0.0128 0.0129
Trichomonas vaginalis CK1 family protein kinase 0.0116 0.0664 0.1263
Schistosoma mansoni hypothetical protein 0.0065 0.0128 0.022
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0168 0.1208 0.1277
Brugia malayi Immunoglobulin I-set domain containing protein 0.0641 0.6169 0.6544
Echinococcus multilocularis myotubularin protein 13 0.0069 0.0173 0.0209
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0091 0.04 0.0419
Echinococcus multilocularis raf serine:threonine protein kinase 0.0112 0.0619 0.0746
Leishmania major protein kinase, putative 0.0093 0.0416 0.0782
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0276 0.2336 0.2818
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0164 0.1162 0.1227
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0414 0.3786 0.3786
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.1268 0.2413
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0155 0.1076 0.1298
Schistosoma mansoni SH2A 0.0065 0.0128 0.022
Entamoeba histolytica serine/threonine protein kinase, putative 0.0059 0.0066 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0006 0.001
Brugia malayi map kinase activated protein kinase protein 2 0.0397 0.3608 0.3825
Brugia malayi cell division control protein 2 homolog 0.0126 0.0768 0.081
Echinococcus multilocularis casein kinase I delta 0.0116 0.0664 0.0801
Schistosoma mansoni serine/threonine protein kinase 0.0269 0.2268 0.3904
Plasmodium falciparum casein kinase 1 0.0116 0.0664 0.1254
Schistosoma mansoni rac gtpase activating protein 0.0061 0.0082 0.014
Giardia lamblia Kinase, CMGC CLK 0.016 0.1128 0.2046
Schistosoma mansoni serine/threonine protein kinase 0.0168 0.1208 0.208
Echinococcus multilocularis tyrosine kinase 0.0116 0.0665 0.0802
Echinococcus multilocularis signal transduction protein lnk realted 0.0065 0.0128 0.0154
Brugia malayi serine/threonine kinase 12 0.0554 0.5253 0.5572
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0356 0.3179 0.3179
Loa Loa (eye worm) hypothetical protein 0.021 0.1646 0.1741
Loa Loa (eye worm) hypothetical protein 0.0117 0.0673 0.0708
Loa Loa (eye worm) TK protein kinase 0.0287 0.2456 0.2601
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Trichomonas vaginalis CAMK family protein kinase 0.0223 0.1781 0.3389
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0267 0.2244 0.2376
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0356 0.3179 0.3369
Echinococcus granulosus cyclin dependent kinase 7 0.0117 0.0677 0.0677
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.029 0.2485 0.4724
Echinococcus multilocularis twitchin 0.0069 0.0173 0.0208
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0107 0.0184
Schistosoma mansoni protein kinase C mu 0.0243 0.1991 0.3427
Trichomonas vaginalis CAMK family protein kinase 0.0275 0.233 0.4435
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0469 0.0892
Loa Loa (eye worm) hypothetical protein 0.0178 0.1307 0.1382
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0246 0.2024 0.2024
Echinococcus multilocularis unc 13 (munc13) 0.0066 0.0133 0.016
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0188 0.1413 0.2681
Entamoeba histolytica hypothetical protein 0.0374 0.3365 0.6405
Plasmodium vivax glycogen synthase kinase 3, putative 0.0136 0.087 0.1647
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0006 0.001
Giardia lamblia Kinase, CAMK CAMKL 0.0105 0.0547 0.0926
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0423 0.3878 0.3878
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0437 0.4025 0.4268
Echinococcus multilocularis tyrosine protein kinase Abl 0.0238 0.1945 0.2346
Echinococcus granulosus growth factor receptor bound protein 2 0.0113 0.0626 0.0626
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Giardia lamblia Kinase, NEK 0.0143 0.0947 0.1698
Leishmania major protein kinase, putative 0.0059 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.0102 0.0514 0.054
Plasmodium vivax unspecified product 0.0174 0.1268 0.2405
Loa Loa (eye worm) TK/EPH protein kinase 0.0132 0.0825 0.0869
Schistosoma mansoni tyrosine kinase 0.0402 0.3663 0.6305
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0094 0.043 0.0519
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0152 0.1037 0.1037
Echinococcus granulosus casein kinase i 0.0116 0.0664 0.0664
Onchocerca volvulus 0.0952 0.9423 1
Onchocerca volvulus 0.021 0.1646 0.1717
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0089 0.0384 0.0384
Loa Loa (eye worm) hypothetical protein 0.0146 0.0972 0.1026
Toxoplasma gondii CMGC kinase, CK2 family 0.0174 0.1268 0.2405
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0092 0.0407 0.0764
Brugia malayi casein kinase I 0.0116 0.0664 0.0699
Echinococcus granulosus tyrosine kinase 0.0116 0.0665 0.0665
Brugia malayi SH2 domain containing protein 0.0065 0.0128 0.0129
Echinococcus multilocularis tensin 0.0065 0.0128 0.0154
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0146 0.0976 0.1849
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0582 0.5551 0.6696
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Echinococcus granulosus nervana 2 0.0122 0.0721 0.0721
Entamoeba histolytica protein kinase 2, putative 0.0163 0.1158 0.2205
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0126 0.0763 0.1314
Entamoeba histolytica protein kinase domain containing protein 0.0086 0.0348 0.0663
Brugia malayi Fes/CIP4 homology domain containing protein 0.0119 0.069 0.0727
Brugia malayi SH2 domain containing protein 0.0116 0.0665 0.07
Schistosoma mansoni protein kinase 0.0116 0.0664 0.1143
Echinococcus multilocularis expressed protein 0.0091 0.04 0.0483
Schistosoma mansoni shc transforming protein 0.0065 0.0128 0.022
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0126 0.0768 0.1453
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.012 0.0709 0.1339
Trichomonas vaginalis STE family protein kinase 0.0094 0.043 0.0818
Echinococcus granulosus cyclin dependent kinase 19 0.0171 0.1235 0.1235
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0091 0.0403 0.0693
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0062 0.0094 0.0178
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0101 0.0505 0.053
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0384 0.0729
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0102 0.0515 0.054
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0059 0.0067 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0332 0.2924 0.5566
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0085 0.0338 0.0408
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0397 0.3608 0.3608
Brugia malayi Protein kinase domain containing protein 0.0089 0.0384 0.0401
Echinococcus granulosus dual specificity 0.0146 0.0976 0.0976
Brugia malayi Immunoglobulin I-set domain containing protein 0.008 0.0285 0.0296
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0094 0.043 0.0519
Brugia malayi Protein kinase domain containing protein 0.0091 0.04 0.0419
Echinococcus multilocularis mitogen activated protein kinase 0.0092 0.0407 0.0491
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.191 0.3288
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0105 0.0547 0.1031
Entamoeba histolytica protein kinase, putative 0.0554 0.5253 1
Schistosoma mansoni neuroglian 0.0059 0.0067 0.0116
Brugia malayi Variant SH3 domain containing protein 0.0109 0.0589 0.062
Plasmodium vivax serine/threonine protein kinase, putative 0.0091 0.04 0.0751
Schistosoma mansoni tyrosine kinase 0.0447 0.4133 0.7115
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0554 0.5253 1
Schistosoma mansoni tyrosine kinase 0.0114 0.0643 0.1106
Trichomonas vaginalis CAMK family protein kinase 0.0275 0.233 0.4435
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0472 0.0897
Echinococcus granulosus expressed conserved protein 0.0065 0.0128 0.0128
Echinococcus granulosus protein kinase 0.0101 0.0503 0.0503
Echinococcus multilocularis SHC transforming protein 3 0.0065 0.0128 0.0154
Entamoeba histolytica PH domain containing protein kinase, putative 0.0172 0.1251 0.2381
Schistosoma mansoni serine/threonine protein kinase 0.008 0.0285 0.049
Echinococcus multilocularis mitogen activated protein kinase 11 0.029 0.2485 0.2997
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0217 0.1724 0.3275
Loa Loa (eye worm) hypothetical protein 0.0061 0.0081 0.008
Trichomonas vaginalis STE family protein kinase 0.0094 0.043 0.0818
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0641 0.6169 0.6544
Echinococcus multilocularis dual specificity 0.0146 0.0976 0.1178
Leishmania major serine/threonine-protein kinase, putative 0.0059 0.0066 0.0115
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0126 0.0768 0.0768
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0065 0.0128 0.022
Onchocerca volvulus 0.0329 0.2896 0.3048
Echinococcus granulosus neuroglian 0.0059 0.0067 0.0067
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.016 0.1127 0.194
Entamoeba histolytica protein kinase, putative 0.0217 0.1724 0.3282
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0209 0.1633 0.1633
Echinococcus granulosus SH2 motif 0.0065 0.0128 0.0128
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0116 0.0664 0.0699
Loa Loa (eye worm) hypothetical protein 0.0109 0.0589 0.062
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0207 0.1613 0.1613
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0067 0.0065
Brugia malayi Immunoglobulin I-set domain containing protein 0.0274 0.2317 0.2454
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0067 0.0065
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Schistosoma mansoni protein kinase 0.0122 0.0724 0.1246
Schistosoma mansoni tyrosine kinase 0.016 0.1127 0.194
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0221 0.1768 0.1871
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0136 0.087 0.1647
Trypanosoma brucei casein kinase I, isoform 2 0.0116 0.0664 0.1254
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0142 0.0931 0.1123
Entamoeba histolytica cell division protein kinase 2, putative 0.0134 0.085 0.1618
Brugia malayi ephrin receptor 1 precursor 0.0081 0.0295 0.0307
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0158 0.1099 0.116
Echinococcus granulosus Protein kinase C brain isozyme 0.0384 0.347 0.347
Echinococcus granulosus roundabout 2 0.0059 0.0067 0.0067
Brugia malayi Protein kinase domain containing protein 0.0332 0.2924 0.3099
Schistosoma mansoni kinase 0.0086 0.0348 0.06
Entamoeba histolytica PH domain containing protein kinase, putative 0.0172 0.1251 0.2381
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0091 0.04 0.0751
Trichomonas vaginalis CMGC family protein kinase 0.0092 0.0407 0.0774
Entamoeba histolytica serine/threonine protein kinase, putative 0.0275 0.233 0.4436
Echinococcus granulosus tyrosine protein kinase shark 0.0536 0.5068 0.5068
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0065 0.0128 0.0128
Plasmodium vivax serine/threonine-protein kinase Nek1, putative 0.0059 0.0066 0.0115
Brugia malayi Tensin 0.0065 0.0128 0.0129
Brugia malayi Sex muscle abnormal protein 5 0.0109 0.0589 0.062
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0469 0.0807
Onchocerca volvulus 0.0116 0.0665 0.0673
Loa Loa (eye worm) hypothetical protein 0.014 0.0919 0.0969
Schistosoma mansoni tyrosine kinase 0.016 0.1127 0.194
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0188 0.1413 0.2681
Echinococcus granulosus cyclin dependent kinase 9 0.0094 0.043 0.043
Schistosoma mansoni hypothetical protein 0.0061 0.0081 0.0139
Trichomonas vaginalis STE family protein kinase 0.0073 0.0207 0.0393
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0055 0.0021 0.0025
Brugia malayi Stress-activated protein kinase jnk-1 0.0269 0.2268 0.2402
Trypanosoma cruzi casein kinase, putative 0.0116 0.0664 0.1254
Echinococcus multilocularis calcium dependent protein kinase 0.0104 0.0535 0.0645
Echinococcus granulosus casein kinase I gamma 0.0219 0.1742 0.1742
Brugia malayi Protein kinase domain 0.0094 0.043 0.0451
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.1268 0.2413
Loa Loa (eye worm) SRC-1 0.0276 0.2336 0.2475
Plasmodium falciparum calcium-dependent protein kinase 4 0.0146 0.0972 0.1841
Echinococcus multilocularis tyrosine protein kinase 0.0287 0.2456 0.2962
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0079 0.0274 0.033
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0112 0.0623 0.0623
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0407 0.07
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0094 0.043 0.043
Brugia malayi Ras association domain family 1 isoform A 0.0061 0.0081 0.008
Brugia malayi serine/threonine-protein kinase PAK 7 0.0238 0.1936 0.205
Onchocerca volvulus 0.0063 0.0106 0.0077
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0065 0.0128 0.0154
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0348 0.06
Toxoplasma gondii NEK kinase 0.0059 0.0066 0.0115
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.012 0.0709 0.0855
Echinococcus granulosus Diacylglycerol kinase theta 0.0061 0.0081 0.0081
Onchocerca volvulus Serine\/threonine kinase homolog 0.0275 0.233 0.2446
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0664 0.1143
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Echinococcus granulosus casein kinase I alpha 0.0116 0.0664 0.0664
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0275 0.233 0.2811
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.0057 0.0109
Echinococcus multilocularis protein kinase shaggy 0.0136 0.087 0.105
Plasmodium vivax serine/threonine-protein kinase NEK4, putative 0.0059 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Trypanosoma cruzi Protein kinase B 0.0172 0.1251 0.2372
Brugia malayi hypothetical protein 0.0102 0.0514 0.054
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Schistosoma mansoni caspase-7 (C14 family) 0.0103 0.0528 0.0908
Loa Loa (eye worm) hypothetical protein 0.0273 0.2308 0.2444
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0126 0.0763 0.1314
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0223 0.1781 0.1884
Echinococcus granulosus tyrosine protein kinase HCK 0.0167 0.1193 0.1193
Loa Loa (eye worm) hypothetical protein 0.0334 0.2943 0.3119
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Entamoeba histolytica protein kinase, putative 0.0089 0.0384 0.073
Echinococcus granulosus defective proboscis extension response 0.0091 0.0403 0.0403
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Onchocerca volvulus 0.014 0.0919 0.0943
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0116 0.0665 0.1266
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0079 0.0274 0.033
Schistosoma mansoni growth factor receptor-bound protein 0.0109 0.0589 0.1015
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0092 0.0407 0.0764
Loa Loa (eye worm) hypothetical protein 0.0063 0.0105 0.0105
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0243 0.1991 0.2108
Brugia malayi protein C17H12.11 0.006 0.0077 0.0076
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.012 0.0709 0.1339
Echinococcus multilocularis neuroglian 0.0059 0.0067 0.0081
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0136 0.087 0.1498
Loa Loa (eye worm) hypothetical protein 0.0063 0.0105 0.0105
Plasmodium falciparum calcium-dependent protein kinase 1 0.0146 0.0972 0.1841
Loa Loa (eye worm) TK/FER protein kinase 0.0116 0.0665 0.07
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0079 0.0274 0.0274
Plasmodium falciparum protein kinase 5 0.0126 0.0768 0.1453
Entamoeba histolytica protein kinase, putative 0.0554 0.5253 1
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0936 0.9255 0.9822
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0142 0.0931 0.1763
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.1742 0.2999
Brugia malayi hypothetical protein 0.0085 0.0338 0.0353
Trypanosoma cruzi polo-like protein kinase, putative 0.0275 0.233 0.4429
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0016 0.0027
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.018 0.133 0.2532
Echinococcus multilocularis growth factor receptor bound protein 2 0.0109 0.0589 0.0711
Echinococcus multilocularis SH2 motif 0.0065 0.0128 0.0154
Echinococcus multilocularis aurora kinase A 0.0554 0.5253 0.6337
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Brugia malayi Protein kinase domain containing protein 0.0193 0.1464 0.1548
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.0768 0.1323
Schistosoma mansoni caspase-3 (C14 family) 0.0141 0.0927 0.1595
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0122 0.073 0.073
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0146 0.0972 0.1172
Echinococcus granulosus Immunoglobulin 0.0091 0.0403 0.0403
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0232 0.1875 0.1875
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.0847 0.1611
Echinococcus granulosus serine:threonine protein kinase N2 0.0329 0.2894 0.2894
Entamoeba histolytica cell division protein kinase 2, putative 0.0126 0.0768 0.1463
Echinococcus granulosus SH2 domain containing adapter protein F 0.0065 0.0128 0.0128
Echinococcus granulosus serine:threonine protein kinase 0.0122 0.072 0.072
Trypanosoma cruzi polo-like protein kinase, putative 0.0275 0.233 0.4429
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0146 0.0972 0.1172
Trichomonas vaginalis conserved hypothetical protein 0.0098 0.0472 0.0897
Echinococcus granulosus caspase 2 0.0103 0.0528 0.0528
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0171 0.1235 0.149
Echinococcus granulosus tyrosine protein kinase Fyn 0.0276 0.2336 0.2336
Loa Loa (eye worm) TK/ALK protein kinase 0.0557 0.5284 0.5605
Trichomonas vaginalis AGC family protein kinase 0.0143 0.0947 0.1802
Echinococcus multilocularis serine:threonine protein kinase 38 0.0201 0.1557 0.1878
Loa Loa (eye worm) hypothetical protein 0.0114 0.0643 0.0676
Trichomonas vaginalis CK1 family protein kinase 0.0116 0.0664 0.1263
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0059 0.0067 0.0116
Onchocerca volvulus 0.0116 0.0664 0.0671
Brugia malayi Protein kinase domain containing protein 0.0201 0.1557 0.1647
Plasmodium falciparum NIMA related kinase 2 0.0059 0.0066 0.0115
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0006 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0384 0.066
Echinococcus granulosus tyrosine protein kinase Src42A 0.0184 0.1374 0.1374
Brugia malayi cell division control protein 2 homolog 0.0123 0.0733 0.0772
Echinococcus multilocularis cyclin dependent kinase 1 0.0126 0.0768 0.0927
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.016 0.1128 0.2137
Brugia malayi P38 map kinase family protein 2 0.029 0.2485 0.2633
Trichomonas vaginalis AGC family protein kinase 0.0332 0.2924 0.5566
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0146 0.0976 0.103
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0465 0.0801
Schistosoma mansoni serine/threonine-protein kinase 0.0172 0.1251 0.2153
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0069 0.0172 0.5
Brugia malayi cyclin-dependent kinase 7 homolog 0.0125 0.0759 0.0799
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0146 0.0972 0.1026
Loa Loa (eye worm) hypothetical protein 0.0069 0.0173 0.0177
Echinococcus multilocularis 0.0171 0.1237 0.1492
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0109 0.0589 0.062
Echinococcus granulosus signal transduction protein lnk realted 0.0065 0.0128 0.0128
Brugia malayi STE20-like kinase MST 0.0262 0.2192 0.2321
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0554 0.5253 1
Trichomonas vaginalis AGC family protein kinase 0.0332 0.2924 0.5566
Loa Loa (eye worm) raf kinase 0.0061 0.0081 0.008
Leishmania major protein kinase A catalytic subunit 0.012 0.0709 0.1339
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0059 0.0067 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Brugia malayi Protein kinase domain containing protein 0.0936 0.9255 0.9822
Brugia malayi Immunoglobulin I-set domain containing protein 0.0059 0.0067 0.0065
Trichomonas vaginalis STE family protein kinase 0.0188 0.1413 0.2689
Trichomonas vaginalis CMGC family protein kinase 0.0146 0.0976 0.1858
Loa Loa (eye worm) hypothetical protein 0.0066 0.0133 0.0135
Loa Loa (eye worm) hypothetical protein 0.0091 0.0403 0.0421
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0092 0.0407 0.0764
Loa Loa (eye worm) SH2 domain-containing protein 0.0065 0.0128 0.0129
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0124 0.0751 0.0791
Trichomonas vaginalis STE family protein kinase 0.0093 0.0416 0.0792
Brugia malayi phosphoinositide-dependent protein kinase I 0.0089 0.0384 0.0401
Plasmodium falciparum calcium-dependent protein kinase 2 0.0146 0.0972 0.1841
Echinococcus multilocularis hypothetical protein 0.01 0.0497 0.0599
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Echinococcus multilocularis 0.0119 0.069 0.0833
Trichomonas vaginalis AGC family protein kinase 0.0554 0.5253 1
Echinococcus granulosus expressed protein 0.0091 0.04 0.04
Entamoeba histolytica protein kinase domain containing protein 0.0136 0.087 0.1656
Schistosoma mansoni serine/threonine kinase 0.0201 0.1557 0.268
Brugia malayi Protein kinase domain containing protein 0.0303 0.2624 0.278
Giardia lamblia Kinase, CMGC DYRK 0.0146 0.0976 0.1754
Schistosoma mansoni serine/threonine protein kinase 0.0235 0.191 0.3288
Giardia lamblia Kinase, STE STE20 0.0094 0.043 0.0702
Leishmania major protein kinase, putative,serine/threonine-protein kinase Nek1, putative 0.0059 0.0066 0.0115
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0099 0.0488 0.0512
Entamoeba histolytica tyrosin kinase, putative 0.0058 0.0057 0.0109
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.012 0.0709 0.1339
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Echinococcus granulosus casein kinase ii subunit alpha 0.0174 0.1268 0.1268
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0006 0.001
Plasmodium falciparum calcium-dependent protein kinase 3 0.0146 0.0972 0.1841
Trichomonas vaginalis AGC family protein kinase 0.0097 0.0465 0.0884
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0146 0.0972 0.1841
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0554 0.5253 0.6337
Schistosoma mansoni serine/threonine protein kinase 0.0142 0.0934 0.1607
Echinococcus multilocularis caspase 2 0.0103 0.0528 0.0636
Trichomonas vaginalis STE family protein kinase 0.0094 0.043 0.0818
Loa Loa (eye worm) hypothetical protein 0.0065 0.0128 0.0129
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0097 0.0465 0.0875
Echinococcus multilocularis protein kinase c eta type 0.0061 0.0081 0.0098
Trypanosoma brucei Casein kinase II 0.0174 0.1268 0.2405
Echinococcus multilocularis dual specificity 0.0146 0.0976 0.1178
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0069 0.0172 0.0317
Brugia malayi Protein kinase domain containing protein 0.0098 0.0469 0.0492
Giardia lamblia Kinase, STE STE20 0.0188 0.1413 0.2596
Schistosoma mansoni ephrin receptor 0.0114 0.0644 0.1108
Echinococcus granulosus c-Jun N-terminal kinases 0.0269 0.2268 0.2268
Schistosoma mansoni vav2 0.0134 0.0856 0.1473
Echinococcus multilocularis mitogen activated protein kinase 11 0.029 0.2485 0.2997
Echinococcus multilocularis cyclin dependent kinase 7 0.0117 0.0677 0.0817
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0006 0.001
Brugia malayi hypothetical protein 0.006 0.0077 0.0076
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0089 0.0384 0.0463
Brugia malayi Kinase associated domain 1 family protein 0.01 0.0497 0.0521
Trypanosoma brucei polo-like protein kinase 0.0275 0.233 0.4429
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.012 0.0709 0.0855
Brugia malayi RhoGAP domain containing protein 0.0061 0.0082 0.008
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0085 0.0338 0.0338
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0146 0.0972 0.1841
Loa Loa (eye worm) hypothetical protein 0.0091 0.0403 0.0421
Loa Loa (eye worm) hypothetical protein 0.0144 0.0958 0.1011
Echinococcus multilocularis Diacylglycerol kinase theta 0.0061 0.0081 0.0098
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0079 0.0273 0.0273
Echinococcus granulosus c src tyrosine kinase 0.016 0.1127 0.1127
Entamoeba histolytica protein kinase, putative 0.0136 0.087 0.1656
Trichomonas vaginalis CMGC family protein kinase 0.0174 0.1268 0.2413
Giardia lamblia Kinase, AGC PKA 0.0163 0.1158 0.2105
Brugia malayi SRC-1 0.0276 0.2336 0.2475
Brugia malayi casein kinase 1, delta 0.0116 0.0664 0.0699
Echinococcus multilocularis serine:threonine protein kinase 3 0.0262 0.2192 0.2643
Echinococcus granulosus calcium activated potassium channel 0.0142 0.0934 0.0934
Schistosoma mansoni protein kinase 0.0188 0.1413 0.2432
Trichomonas vaginalis CAMK family protein kinase 0.0122 0.072 0.137
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0092 0.0407 0.0764
Trypanosoma brucei cdc2-related kinase 1 0.0126 0.0768 0.1453
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0384 0.347 0.4186
Brugia malayi SH2 domain containing protein 0.0065 0.0128 0.0129
Echinococcus multilocularis protein kinase c iota type 0.0343 0.3046 0.3675
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.016 0.1128 0.2137
Brugia malayi Variant SH3 domain containing protein 0.0109 0.0589 0.062
Brugia malayi hypothetical protein 0.0116 0.0665 0.07
Loa Loa (eye worm) RasGEF domain-containing protein 0.0061 0.0081 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0066 0.0125
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0091 0.0403 0.0693
Echinococcus multilocularis Rac GTPase activating protein 1 0.0061 0.0082 0.0098
Schistosoma mansoni vesicular amine transporter 0.0091 0.0403 0.0693
Echinococcus granulosus tyrosine protein kinase 0.0287 0.2456 0.2456
Schistosoma mansoni suppressor of cytokine signaling 0.0065 0.0128 0.022
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0146 0.0976 0.103
Plasmodium vivax calcium-dependent protein kinase, putative 0.0146 0.0972 0.1841
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0222 0.1771 0.1771
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0006 0.001
Loa Loa (eye worm) CAMK/CAMKL/NIM1 protein kinase 0.0123 0.0733 0.0772
Echinococcus granulosus mitogen activated protein kinase 0.0092 0.0407 0.0407
Trypanosoma cruzi casein kinase, putative 0.0116 0.0664 0.1254
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0053 0.0006 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0107 0.0184
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0093 0.0421 0.0791
Schistosoma mansoni tyrosine kinase 0.0255 0.2122 0.3653
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0066 0.0114
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0063 0.0107 0.0192
Trichomonas vaginalis AGC family protein kinase 0.0071 0.0186 0.0354
Loa Loa (eye worm) TK/FER protein kinase 0.0116 0.0665 0.07
Entamoeba histolytica protein kinase, putative 0.0079 0.0274 0.0521
Echinococcus granulosus serine threonine protein kinase nrc 0.0163 0.1158 0.1158
Schistosoma mansoni kinase 0.0293 0.252 0.4338
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0086 0.0348 0.0364
Brugia malayi Protein kinase domain containing protein 0.0219 0.1745 0.1846
Brugia malayi diacylglycerol kinase 0.0061 0.0081 0.008
Schistosoma mansoni tyrosine kinase 0.0351 0.3125 0.538
Schistosoma mansoni serine/threonine protein kinase 0.0554 0.5253 0.9043
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0437 0.4025 0.4268
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0209 0.1633 0.1727
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0201 0.1557 0.1557
Echinococcus multilocularis cyclin dependent kinase 9 0.0094 0.043 0.0519
Echinococcus multilocularis Glutaredoxin protein 5 0.0122 0.0721 0.087
Echinococcus multilocularis SH2 motif 0.0065 0.0128 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0465 0.0885
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0071 0.0186 0.0354
Schistosoma mansoni serine/threonine protein kinase 0.012 0.0709 0.122
Entamoeba histolytica protein kinase, putative 0.0081 0.0299 0.0569
Onchocerca volvulus 0.0287 0.2459 0.2583
Echinococcus granulosus tyrosine protein kinase Lyn 0.0317 0.2773 0.2773
Echinococcus granulosus mitogen activated protein kinase 11 0.029 0.2485 0.2485
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0069 0.0172 0.0208
Brugia malayi Protein kinase domain containing protein 0.0102 0.0515 0.054
Echinococcus granulosus dual specificity 0.0217 0.1724 0.1724
Trichomonas vaginalis AGC family protein kinase 0.0332 0.2924 0.5566
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0114 0.0643 0.0643
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0276 0.2336 0.2336
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0465 0.0801
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0065 0.0128 0.0155
Brugia malayi Temporarily assigned gene name protein 59 0.0127 0.0776 0.0818
Loa Loa (eye worm) TK/ROR protein kinase 0.0079 0.0273 0.0284
Leishmania major protein kinase, putative 0.0554 0.5253 1
Echinococcus granulosus rho-associated protein kinase 1 0.0329 0.2896 0.2896
Onchocerca volvulus 0.0088 0.0366 0.0354
Trichomonas vaginalis CK1 family protein kinase 0.0116 0.0664 0.1263
Trichomonas vaginalis CMGC family protein kinase 0.0098 0.0469 0.0892
Loa Loa (eye worm) CDC7 protein kinase 0.0098 0.0469 0.0492
Loa Loa (eye worm) hypothetical protein 0.0363 0.3256 0.3451
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0414 0.3786 0.4014
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0094 0.0178
Echinococcus granulosus activated cdc42 kinase 1 0.0215 0.1695 0.1695
Brugia malayi Protein kinase domain containing protein 0.0116 0.0665 0.07
Schistosoma mansoni serine/threonine kinase 0.023 0.1862 0.3205
Trypanosoma cruzi p21-activated kinase 3, putative 0.0063 0.0107 0.0192
Brugia malayi SH2 domain containing protein 0.0065 0.0128 0.0129
Echinococcus granulosus titin 0.008 0.0285 0.0285

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 67.554 uM PUBCHEM_BIOASSAY: Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504766, AID504790] ChEMBL. No reference
IC50 (functional) > 67.554 uM PUBCHEM_BIOASSAY: Counterscreen for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): luminescence-based cell-based high throughput dose response assay to identify compounds that interfere with the UAS/Gal4 system and/or luciferase reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504766, AID504790] ChEMBL. No reference
Potency (functional) 0.1 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.9811 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-7. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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