Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | musashi | 0.0033 | 0.0618 | 0.0618 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.002 | 0.027 | 0.5136 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0648 | 0.3867 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0033 | 0.0618 | 0.0593 |
Echinococcus granulosus | serine:threonine protein kinase SMG1 | 0.0011 | 0.0029 | 0.0029 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0035 | 0.068 | 0.4082 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0644 | 0.1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0026 | 0.0426 | 0.0401 |
Brugia malayi | MH2 domain containing protein | 0.0132 | 0.3366 | 0.5405 |
Schistosoma mansoni | lamin | 0.0033 | 0.0618 | 0.0618 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0067 | 0.1573 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0047 | 0.102 | 0.6333 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0067 | 0.1573 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0026 | 0.0026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.0026 | 0.0026 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0648 | 0.0648 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0146 | 0.0146 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0026 | 0.0026 |
Schistosoma mansoni | thyroid hormone receptor | 0.015 | 0.3874 | 0.3874 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.0026 | 0.0026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0011 | 0.0029 | 0.004 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0011 | 0.0029 | 0.004 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.002 | 0.027 | 0.3336 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0047 | 0.102 | 0.102 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.002 | 0.027 | 0.027 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0028 | 0.0498 | 0.0701 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.002 | 0.027 | 0.0395 |
Onchocerca volvulus | 0.0033 | 0.0618 | 0.0836 | |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.002 | 0.027 | 0.3336 |
Plasmodium falciparum | importin beta, putative | 0.0035 | 0.068 | 0.5342 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.002 | 0.027 | 0.1362 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0146 | 0.012 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.0026 | 0.0026 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0047 | 0.102 | 1 |
Schistosoma mansoni | ran | 0.0026 | 0.0426 | 0.0426 |
Echinococcus granulosus | importin subunit beta 1 | 0.0035 | 0.068 | 0.068 |
Trichomonas vaginalis | set domain proteins, putative | 0.0267 | 0.7102 | 1 |
Brugia malayi | Importin beta-1 subunit | 0.0035 | 0.068 | 0.1059 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.002 | 0.027 | 0.2731 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0026 | 0.0026 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0035 | 0.068 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0047 | 0.102 | 0.6333 |
Schistosoma mansoni | thyroid hormone receptor | 0.015 | 0.3874 | 0.3874 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0026 | 0.0426 | 0.0647 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0415 | 0.039 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0156 | 0.4023 | 0.4023 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0139 | 0.3565 | 0.3565 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.002 | 0.027 | 0.027 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.0026 | 0.0026 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0415 | 0.2326 |
Onchocerca volvulus | 0.0034 | 0.0648 | 0.0879 | |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.0026 | 0.0026 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1073 | 0.1694 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0648 | 0.0648 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.0026 | 0.0026 |
Echinococcus granulosus | lamin dm0 | 0.0033 | 0.0618 | 0.0618 |
Schistosoma mansoni | hypothetical protein | 0.0372 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.1573 | 0.1573 |
Echinococcus granulosus | lamin | 0.0033 | 0.0618 | 0.0618 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.016 | 0.4147 | 0.4147 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0648 | 0.0648 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0026 | 0.0426 | 0.0426 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Brugia malayi | RNA, U transporter 1 | 0.0099 | 0.2456 | 0.3932 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0026 | 0.0026 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0016 | 0.0152 | 0.0152 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0415 | 0.5698 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0047 | 0.102 | 0.1436 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0132 | 0.3366 | 0.3349 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0415 | 0.8236 |
Schistosoma mansoni | fkbp-rapamycin associated protein | 0.0011 | 0.0029 | 0.0029 |
Treponema pallidum | bacterioferrin (TpF1) | 0.001 | 0 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0135 | 0.011 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.1573 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0011 | 0.0029 | 0.0005 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0067 | 0.1573 | 0.1573 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0648 | 0.0648 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0146 | 0.0146 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.002 | 0.027 | 0.5136 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0011 | 0.0029 | 0.004 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.0026 | 0.0026 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0026 | 0.0426 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0135 | 0.011 |
Schistosoma mansoni | lamin | 0.0033 | 0.0618 | 0.0618 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0168 | 0.023 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0146 | 0.0194 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.002 | 0.027 | 0.0395 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0415 | 0.063 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0026 | 0.0426 | 0.0215 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0132 | 0.3366 | 0.3349 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0026 | 0.0426 | 0.8463 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0618 | 0.0593 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0026 | 0.0026 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0028 | 0.0498 | 0.0701 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0146 | 0.0146 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.0026 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0146 | 0.0146 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.016 | 0.4147 | 0.6669 |
Onchocerca volvulus | 0.0267 | 0.7102 | 1 | |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.001 | 0 | 0.5 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0235 | 0.6206 | 0.6196 |
Brugia malayi | Pre-SET motif family protein | 0.0235 | 0.6206 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.002 | 0.027 | 0.0245 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Echinococcus multilocularis | lamin dm0 | 0.0033 | 0.0618 | 0.0618 |
Trichomonas vaginalis | importin beta-1, putative | 0.0028 | 0.0498 | 0.0701 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.0199 | 0.0281 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0644 | 0.0644 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.002 | 0.027 | 0.0245 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | acetyltransferase | 0.016 | 0.4147 | 0.4132 |
Echinococcus multilocularis | serine:threonine protein kinase SMG1 | 0.0011 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | intermediate filament protein | 0.0033 | 0.0618 | 0.0593 |
Onchocerca volvulus | 0.0033 | 0.0618 | 0.0836 | |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.0026 | 0.0026 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0027 | 0.0476 | 0.9536 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0415 | 0.8236 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0152 | 0.0126 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0027 | 0.0476 | 0.0476 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.1573 | 0.1573 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1073 | 0.105 |
Schistosoma mansoni | importin beta-1 | 0.0035 | 0.068 | 0.068 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0644 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0648 | 0.0623 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.002 | 0.027 | 0.5136 |
Schistosoma mansoni | ran | 0.0026 | 0.0426 | 0.0426 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Entamoeba histolytica | hypothetical protein | 0.0028 | 0.0498 | 0.5317 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0016 | 0.0152 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0029 | 0.0003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.0064 | 0.009 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.001 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0146 | 0.0146 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.015 | 0.3874 | 0.3874 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1073 | 0.105 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0146 | 0.0146 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.0026 | 0.0026 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.002 | 0.027 | 0.3336 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.0026 | 0.0026 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.1573 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0035 | 0.068 | 0.068 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.002 | 0.027 | 0.5136 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0067 | 0.1573 | 1 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.002 | 0.027 | 0.5136 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0415 | 0.1116 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0011 | 0.0029 | 0.004 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0013 | 0.0064 | 0.009 |
Leishmania major | GTP-binding protein, putative | 0.0026 | 0.0426 | 0.1198 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0648 | 0.0648 |
Schistosoma mansoni | intermediate filament proteins | 0.0033 | 0.0618 | 0.0618 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.0199 | 0.0174 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0034 | 0.0648 | 0.0648 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0011 | 0.0029 | 0.004 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0043 | 0.0911 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.037 | 0.0345 |
Trichomonas vaginalis | ran, putative | 0.0026 | 0.0426 | 0.0599 |
Echinococcus granulosus | serine protein kinase ATM | 0.0027 | 0.0476 | 0.0476 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0372 | 1 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0146 | 0.012 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.0026 | 0.0026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0067 | 0.1573 | 0.1573 |
Echinococcus multilocularis | lamin | 0.0033 | 0.0618 | 0.0618 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Brugia malayi | intermediate filament protein | 0.0033 | 0.0618 | 0.0958 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.002 | 0.027 | 0.027 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0011 | 0.0029 | 0.004 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0027 | 0.0476 | 0.067 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0043 | 0.0911 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0043 | 0.0911 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0476 | 0.5071 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0139 | 0.3565 | 0.3565 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0034 | 0.0648 | 0.0648 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.3565 | 0.3565 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.0026 | 0.0026 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0648 | 0.1006 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1073 | 0.1694 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.002 | 0.027 | 0.3336 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Plasmodium vivax | importin-beta 2, putative | 0.0035 | 0.068 | 0.4383 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.0026 | 0.0026 |
Echinococcus multilocularis | snurportin 1 | 0.0372 | 1 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0033 | 0.0618 | 0.0958 |
Echinococcus granulosus | intermediate filament protein | 0.0033 | 0.0618 | 0.0618 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0146 | 0.0146 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.002 | 0.027 | 0.3336 |
Entamoeba histolytica | Ran family GTPase | 0.0026 | 0.0426 | 0.45 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0011 | 0.0029 | 0.004 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.002 | 0.0271 | 0.0008 |
Toxoplasma gondii | FATC domain-containing protein | 0.0027 | 0.0476 | 0.273 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0026 | 0.0426 | 0.2396 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0613 | 0.0613 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.0026 | 0.0026 |
Leishmania major | importin beta-1 subunit, putative | 0.0028 | 0.0498 | 0.1751 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.003 | 0.003 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0026 | 0.0426 | 0.0426 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0027 | 0.0476 | 0.6688 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0027 | 0.0476 | 0.0476 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.002 | 0.027 | 0.027 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0146 | 0.0146 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0146 | 0.0146 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0047 | 0.102 | 0.1436 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0064 | 0.0039 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0146 | 0.0194 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.0026 | 0.0026 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0648 | 0.3845 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.002 | 0.027 | 0.027 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.037 | 0.727 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.0026 | 0.0026 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.002 | 0.027 | 0.2731 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0026 | 0.0426 | 0.587 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.016 | 0.4147 | 0.4147 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.003 | 0.003 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.0026 | 0.0026 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.1573 | 1 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0028 | 0.0498 | 1 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.002 | 0.0271 | 0.5159 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0026 | 0.0426 | 0.2434 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.002 | 0.027 | 0.027 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0026 | 0.0426 | 0.8463 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0035 | 0.068 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.0026 | 0.0026 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.002 | 0.027 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.068 | 0.0656 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0601 | 0.0577 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0027 | 0.0476 | 0.0729 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.003 | 0.003 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0146 | 0.0146 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] | ChEMBL. | No reference |
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.