Detailed information for compound 1457729

Basic information

Technical information
  • TDR Targets ID: 1457729
  • Name: [2-methyl-1-(3-methylphenyl)benzimidazol-5-yl ]-morpholin-4-ylmethanone
  • MW: 335.4 | Formula: C20H21N3O2
  • H donors: 0 H acceptors: 2 LogP: 2.95 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(c1)n1c(C)nc2c1ccc(c2)C(=O)N1CCOCC1
  • InChi: 1S/C20H21N3O2/c1-14-4-3-5-17(12-14)23-15(2)21-18-13-16(6-7-19(18)23)20(24)22-8-10-25-11-9-22/h3-7,12-13H,8-11H2,1-2H3
  • InChiKey: SIPSNLOPNASUND-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [2-methyl-1-(3-methylphenyl)benzimidazol-5-yl]-morpholino-methanone
  • [2-methyl-1-(3-methylphenyl)-5-benzimidazolyl]-morpholinomethanone
  • [2-methyl-1-(3-methylphenyl)benzimidazol-5-yl]-morpholin-4-yl-methanone
  • Oprea1_848739

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens vitamin D (1,25- dihydroxyvitamin D3) receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi steroid hormone receptor vitamin D (1,25- dihydroxyvitamin D3) receptor 427 aa 416 aa 24.5 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0182 0.1144 1
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0117 0.0294
Loa Loa (eye worm) hypothetical protein 0.099 0.6795 0.6795
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0071 0.0366 0.1068
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0071 0.0366 0.0823
Echinococcus multilocularis mothers against decapentaplegic 6 0.0038 0.0136 0.0306
Onchocerca volvulus Protein ultraspiracle homolog 0.0053 0.024 0.1773
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.004 0.015 0.0337
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0053 0.024 0.024
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.004 0.015 0.015
Schistosoma mansoni tyrosine kinase 0.0021 0.0018 0.0027
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0021 0.0018 0.0041
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0175 0.0257
Loa Loa (eye worm) hypothetical protein 0.0076 0.0405 0.0405
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0175 0.0122
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0053 0.024 0.024
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.0677 0.1522
Schistosoma mansoni glutaminase 0.0265 0.1724 0.2537
Schistosoma mansoni thyroid hormone receptor 0.0053 0.024 0.0352
Loa Loa (eye worm) hypothetical protein 0.0287 0.1879 0.1879
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0329 0.217 1
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0028 0.0066 0.0066
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0221 0.0496
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.024 0.024
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0045 0.01
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0175
Echinococcus multilocularis tar DNA binding protein 0.0654 0.4447 1
Toxoplasma gondii isocitrate dehydrogenase 0.0329 0.217 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0021 0.0018 0.0041
Echinococcus multilocularis Glycosyl transferase, family 8 0.0081 0.0436 0.0979
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0175 0.0393
Loa Loa (eye worm) hypothetical protein 0.0248 0.1604 0.1604
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0018 0.0041
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0329 0.217 0.4881
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0329 0.217 1
Echinococcus multilocularis c src tyrosine kinase 0.0021 0.0018 0.0041
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0053 0.024 0.0539
Echinococcus granulosus Smad4 0.0085 0.0465 0.1045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0053 0.024 0.024
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0045 0.0045
Schistosoma mansoni smad1 5 8 and 0.0085 0.0465 0.0684
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0405 1
Schistosoma mansoni Smad4 0.0038 0.0136 0.02
Echinococcus multilocularis Smad4 0.0085 0.0465 0.1045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0244 0.0359
Brugia malayi MH1 domain containing protein 0.0085 0.0465 0.0465
Brugia malayi MH1 domain containing protein 0.0047 0.0199 0.0199
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0018 0.0041
Schistosoma mansoni tyrosine kinase 0.0021 0.0018 0.0027
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0169 0.0248
Trypanosoma cruzi PAB1-binding protein , putative 0.0182 0.1141 0.4842
Loa Loa (eye worm) hypothetical protein 0.0028 0.0066 0.0066
Schistosoma mansoni nuclear receptor 0.0025 0.0045 0.0066
Loa Loa (eye worm) isocitrate dehydrogenase 0.0329 0.217 0.217
Loa Loa (eye worm) nuclear hormone receptor 0.0296 0.1941 0.1941
Brugia malayi ecdysone receptor 0.0025 0.0045 0.0045
Onchocerca volvulus 0.0053 0.024 0.1773
Echinococcus granulosus FTZ F1 alpha 0.0053 0.024 0.0539
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0405 0.5
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.024 0.0539
Schistosoma mansoni tar DNA-binding protein 0.0654 0.4447 0.6544
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0045 0.01
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0175 0.0157
Echinococcus granulosus peregrin 0.0035 0.0117 0.0263
Echinococcus multilocularis geminin 0.0198 0.1252 0.2816
Brugia malayi nuclear receptor NHR-67 0.0025 0.0045 0.0045
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0045 0.0045
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0045 0.0045
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0018 0.0041
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0021 0.0018 0.0041
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0329 0.217 0.4881
Loa Loa (eye worm) hypothetical protein 0.1449 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0244 0.0548
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0244 0.0548
Trypanosoma brucei PAB1-binding protein , putative 0.0182 0.1141 0.4842
Brugia malayi RNA binding protein 0.0654 0.4447 0.4447
Echinococcus multilocularis smad 0.0085 0.0465 0.1045
Brugia malayi jmjC domain containing protein 0.0043 0.0169 0.0169
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0085 0.0465 0.1045
Schistosoma mansoni tar DNA-binding protein 0.0654 0.4447 0.6544
Onchocerca volvulus Bile acid receptor homolog 0.0053 0.024 0.1773
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.0405 0.1655
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0021 0.0018 0.0041
Schistosoma mansoni hypothetical protein 0.0458 0.3076 0.4526
Echinococcus multilocularis tyrosine protein kinase Abl 0.0266 0.1733 0.3897
Loa Loa (eye worm) MH1 domain-containing protein 0.0038 0.0136 0.0136
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0045 0.01
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0175 0.0122
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0175 0.0157
Schistosoma mansoni hypothetical protein 0.0035 0.0117 0.0172
Brugia malayi conserved hypotetical protein 0.0025 0.0045 0.0045
Brugia malayi hypothetical protein 0.0028 0.0066 0.0066
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0053 0.024 0.0352
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0045 0.01
Loa Loa (eye worm) TK/ABL protein kinase 0.0653 0.4439 0.4439
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0175
Mycobacterium ulcerans lipase LipD 0.0043 0.0175 0.0157
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0071 0.0366 0.0823
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0244 0.0359
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0038 0.0136 0.0833
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.024 0.024
Mycobacterium leprae PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH) 0.004 0.015 0.2723
Schistosoma mansoni unc-13 (munc13) 0.004 0.015 0.0221
Brugia malayi hypothetical protein 0.0028 0.0066 0.0066
Schistosoma mansoni coup transcription factor 0.0053 0.024 0.0352
Brugia malayi nuclear receptor RXR 0.0025 0.0045 0.0045
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0053 0.024 0.0539
Loa Loa (eye worm) MH2 domain-containing protein 0.0085 0.0465 0.0465
Brugia malayi Probable ClpP-like protease 0.0076 0.0405 0.0405
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0405 0.1655
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0221 0.4744
Schistosoma mansoni tyrosine kinase 0.0021 0.0018 0.0027
Echinococcus multilocularis glycosyltransferase protein LARGE2 0.0078 0.0418 0.0939
Brugia malayi nuclear hormone receptor 0.0025 0.0045 0.0045
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0244 0.0244
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0329 0.217 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0117 0.0294
Echinococcus granulosus isocitrate dehydrogenase NAD 0.004 0.015 0.0337
Brugia malayi Tyrosine-protein kinase abl-1 0.0266 0.1733 0.1733
Trypanosoma cruzi PAB1-binding protein , putative 0.0182 0.1141 0.4842
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0511 0.0752
Echinococcus multilocularis thyroid hormone receptor alpha 0.0053 0.024 0.0539
Onchocerca volvulus 0.0043 0.0175 0.1183
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0175 0.0567
Onchocerca volvulus Alhambra homolog 0.0035 0.0117 0.0657
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0066 0.0096
Brugia malayi Isocitrate dehydrogenase 0.0329 0.217 0.217
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0053 0.024 0.0352
Brugia malayi MH2 domain containing protein 0.0085 0.0465 0.0465
Loa Loa (eye worm) DR-78 0.0025 0.0045 0.0045
Echinococcus multilocularis mothers against decapentaplegic 2 0.0038 0.0136 0.0306
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Brugia malayi MH2 domain containing protein 0.0085 0.0465 0.0465
Brugia malayi Glycosyl transferase family 8 protein 0.0081 0.0436 0.0436
Loa Loa (eye worm) hypothetical protein 0.004 0.015 0.015
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0066 0.0066
Brugia malayi Bromodomain containing protein 0.0035 0.0117 0.0117
Echinococcus multilocularis GPCR, family 2 0.0458 0.3076 0.6917
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0053 0.024 0.0352
Brugia malayi Probable isocitrate dehydrogenase 0.004 0.015 0.015
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0366 0.1371
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0458 0.3076 0.6917
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0053 0.024 0.024
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.004 0.015 0.015
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0175 0.0175
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0117 0.0172
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0175
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0053 0.024 0.0539
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0175 0.0157
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0175 0.0157
Brugia malayi nuclear receptor RXR 0.0028 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0053 0.024 0.024
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0053 0.024 0.1773
Echinococcus granulosus GPCR family 2 0.0458 0.3076 0.6917
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0053 0.024 0.024
Echinococcus granulosus tyrosine protein kinase ABL1 0.0653 0.4439 0.9983
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0016
Schistosoma mansoni smad1 5 8 and 0.0085 0.0465 0.0684
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0053 0.024 0.024
Schistosoma mansoni smad 0.0038 0.0136 0.02
Loa Loa (eye worm) hypothetical protein 0.0028 0.0066 0.0066
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.0405 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0117 0.0117
Brugia malayi Probable isocitrate dehydrogenase 0.004 0.015 0.015
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0066 0.0147
Brugia malayi MH1 domain containing protein 0.0047 0.0199 0.0199
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0045 0.01
Plasmodium falciparum ataxin-2 like protein, putative 0.0182 0.1141 0.5134
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.024 0.0539
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0329 0.217 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0045 0.01
Brugia malayi Tyrosine-protein kinase abl-1 0.0396 0.2641 0.2641
Mycobacterium tuberculosis Conserved protein 0.0043 0.0175 0.0122
Loa Loa (eye worm) RNA binding protein 0.0654 0.4447 0.4447
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0175 0.0122
Brugia malayi nuclear receptor NHR-88 0.0053 0.024 0.024
Loa Loa (eye worm) MH1 domain-containing protein 0.0085 0.0465 0.0465
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0066 0.0096
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0018 0.0041
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0329 0.217 1
Toxoplasma gondii aldehyde dehydrogenase 0.0071 0.0366 0.1471
Trichomonas vaginalis esterase, putative 0.0043 0.0175 0.0157
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0221 0.0496
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.1813 0.8232
Echinococcus granulosus tar DNA binding protein 0.0654 0.4447 1
Brugia malayi MH2 domain containing protein 0.1247 0.8589 0.8589
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0329 0.217 0.4881
Schistosoma mansoni tar DNA-binding protein 0.0654 0.4447 0.6544
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0366 0.1371
Brugia malayi ecdysteroid receptor 0.0053 0.024 0.024
Schistosoma mansoni nuclear hormone receptor 0.0053 0.024 0.0352
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0175 0.0175
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0117 0.0294
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0053 0.024 0.0539
Brugia malayi SRC-1 0.0021 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0175
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0329 0.217 1
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0021 0.0018 0.0041
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.0405 0.091
Schistosoma mansoni glycosyltransferase-related 0.0081 0.0436 0.0641
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0066 0.0147
Loa Loa (eye worm) MH2 domain-containing protein 0.0038 0.0136 0.0136
Schistosoma mansoni hypothetical protein 0.0081 0.044 0.0648
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0458 0.3076 0.3076
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Mycobacterium tuberculosis Conserved protein 0.0043 0.0175 0.0122
Echinococcus multilocularis isocitrate dehydrogenase 0.0329 0.217 0.4881
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.004 0.015 0.015
Loa Loa (eye worm) SRC-1 0.0021 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0043 0.0175 0.0175
Onchocerca volvulus 0.0043 0.0175 0.1183
Plasmodium vivax ataxin-2 like protein, putative 0.0182 0.1141 0.5134
Brugia malayi hypothetical protein 0.0117 0.0691 0.0691
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0169 0.0379
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0329 0.217 0.4881
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0299 0.1962 0.1962
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0021 0.0018 0.0041
Schistosoma mansoni nuclear receptor 0.0025 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0053 0.024 0.024
Loa Loa (eye worm) transcription factor SMAD2 0.1247 0.8589 0.8589
Schistosoma mansoni thyroid hormone receptor 0.0053 0.024 0.0352
Brugia malayi tailless protein 0.0025 0.0045 0.0045
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.004 0.015 0.0337
Loa Loa (eye worm) hypothetical protein 0.0182 0.1141 0.1141
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.0405 0.5
Schistosoma mansoni hypothetical protein 0.0458 0.3076 0.4526
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0213 0.048
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0045 0.0045
Toxoplasma gondii ABC1 family protein 0.0043 0.0175 0.0567
Loa Loa (eye worm) hypothetical protein 0.0182 0.1144 0.1144
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0458 0.3076 0.6917
Echinococcus multilocularis ecdysone induced protein 78C 0.0053 0.024 0.0539
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0045 0.0066
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0045 0.01
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0379 0.0379
Schistosoma mansoni Smad4 0.0038 0.0136 0.02
Leishmania major hypothetical protein, conserved 0.0182 0.1141 0.4905
Schistosoma mansoni Smad4 0.0085 0.0465 0.0684
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0053 0.024 0.024
Echinococcus granulosus tyrosine protein kinase Src64B 0.0021 0.0018 0.0041
Loa Loa (eye worm) nuclear factor I 0.0047 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0053 0.024 0.024
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.0405 1
Brugia malayi hypothetical protein 0.0025 0.0045 0.0045
Trichomonas vaginalis glutaminase, putative 0.0265 0.1724 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0175 0.0257
Echinococcus multilocularis Glycosyltransferase protein LARGE1 0.006 0.029 0.0652
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0045 0.01
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0175 0.0122
Echinococcus granulosus mothers against decapentaplegic 2 0.0038 0.0136 0.0306
Brugia malayi Steroid receptor seven-up type 2 0.0324 0.2136 0.2136
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0244 0.0548
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0045 0.0045
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.0405 0.091
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.024 0.0539
Brugia malayi hypothetical protein 0.0025 0.0045 0.0045
Loa Loa (eye worm) TAR-binding protein 0.0654 0.4447 0.4447
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.0677 0.1522
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0053 0.024 0.0539
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.0405 0.1655
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0045 0.0045
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0053 0.024 0.0352
Brugia malayi nuclear hormone receptor 0.0053 0.024 0.024
Brugia malayi hypothetical protein 0.0182 0.1141 0.1141
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0045 0.0066
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0021 0.0018 0.0041
Loa Loa (eye worm) beta-lactamase 0.0043 0.0175 0.0175
Mycobacterium ulcerans hypothetical protein 0.0043 0.0175 0.0157
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0329 0.217 1
Schistosoma mansoni tar DNA-binding protein 0.0654 0.4447 0.6544
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0021 0.0018 0.0027
Schistosoma mansoni hypothetical protein 0.099 0.6795 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0038 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0053 0.024 0.024
Toxoplasma gondii isocitrate dehydrogenase 0.0329 0.217 1
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.0405 0.0596
Echinococcus granulosus Glycosyltransferase protein LARGE1 0.006 0.029 0.0652
Mycobacterium leprae Probable lipase LipE 0.0043 0.0175 0.3429
Plasmodium falciparum ataxin-2 like protein, putative 0.0182 0.1141 0.5134
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0117 0.0263
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0213 0.048
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0366 0.1371
Schistosoma mansoni zinc finger protein 0.0025 0.0045 0.0066
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0329 0.217 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0021 0.0018 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0053 0.024 0.024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.024 0.024
Mycobacterium ulcerans glutaminase 0.0265 0.1724 1
Brugia malayi latrophilin 2 splice variant baaae 0.099 0.6795 0.6795
Giardia lamblia PHD finger protein 15 0.0035 0.0117 0.5
Loa Loa (eye worm) hypothetical protein 0.006 0.0293 0.0293
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.0169 0.0169
Schistosoma mansoni tyrosine kinase 0.0644 0.4374 0.6436
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0066 0.0066
Schistosoma mansoni steroid hormone receptor ad4bp 0.0053 0.024 0.0352
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0329 0.217 0.4881
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0066 0.0066
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0117 0.0117
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0175 0.0122
Brugia malayi isocitrate dehydrogenase 0.0329 0.217 0.217
Schistosoma mansoni smad 0.0085 0.0465 0.0684
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0244 0.0244
Echinococcus granulosus TGF beta signal transducer SmadC 0.0085 0.0465 0.1045
Mycobacterium tuberculosis Conserved protein 0.0043 0.0175 0.0122
Echinococcus granulosus tyrosine protein kinase Src42A 0.0021 0.0018 0.0041
Echinococcus granulosus tyrosine protein kinase Lyn 0.0021 0.0018 0.0041
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0021 0.0018 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.024 0.024
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0175 0.0157
Echinococcus multilocularis glycosyltransferase protein LARGE2 0.0078 0.0418 0.0939
Brugia malayi beta-lactamase family protein 0.0043 0.0175 0.0175
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0324 0.2136 0.4804
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0045 0.01
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0045 0.0066
Loa Loa (eye worm) glutaminase 0.0265 0.1724 0.1724
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.004 0.015 0.015
Schistosoma mansoni RAR-like nuclear receptor 0.0053 0.024 0.0352
Onchocerca volvulus 0.0043 0.0175 0.1183
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0053 0.024 0.0539
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0053 0.024 0.024
Loa Loa (eye worm) latrophilin receptor protein 2 0.0458 0.3076 0.3076
Mycobacterium ulcerans beta-lactamase 0.0043 0.0175 0.0157
Brugia malayi MH1 domain containing protein 0.0085 0.0465 0.0465
Loa Loa (eye worm) hypothetical protein 0.0458 0.3076 0.3076
Echinococcus multilocularis FTZ F1 alpha 0.0053 0.024 0.0539
Echinococcus granulosus mothers against decapentaplegic 5 0.0085 0.0465 0.1045
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.004 0.015 0.0337
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0053 0.024 0.024
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.0169 0.0379
Echinococcus multilocularis glycosyltransferase protein LARGE2 0.0078 0.0418 0.0939
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0405 0.1618
Brugia malayi beta-lactamase family protein 0.0043 0.0175 0.0175
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0221 0.035
Echinococcus granulosus mothers against decapentaplegic 6 0.0038 0.0136 0.0306
Schistosoma mansoni retinoic acid receptor RXR 0.0053 0.024 0.0352
Loa Loa (eye worm) Smad1 0.0085 0.0465 0.0465
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0053 0.024 0.024
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1449 1 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0199 0.0199
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0045 0.0045
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0045 0.01
Brugia malayi RNA recognition motif domain containing protein 0.0654 0.4447 0.4447
Entamoeba histolytica tartrate dehydrogenase, putative 0.004 0.015 0.5
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0221 0.035
Echinococcus multilocularis mothers against decapentaplegic 5 0.0085 0.0465 0.1045
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0085 0.0465 0.0684
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0458 0.3076 0.6917
Echinococcus granulosus glycosyltransferase protein LARGE2 0.0078 0.0418 0.0939
Brugia malayi AT16019p 0.0021 0.0016 0.0016
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0175 0.0122
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0654 0.4447 0.4447
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0053 0.024 0.024
Brugia malayi steroid hormone receptor 0.0053 0.024 0.024
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0053 0.024 0.024
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.0169 0.0248
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0117 0.0263
Brugia malayi jmjC domain containing protein 0.0115 0.0677 0.0677
Brugia malayi N-terminal motif family protein 0.0182 0.1144 0.1144
Brugia malayi Smad1 0.0085 0.0465 0.0465
Brugia malayi mothers against decapentaplegic homolog 3 0.0038 0.0136 0.0136
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0018 0.0041
Leishmania major hypothetical protein, conserved 0.0043 0.0175 0.0122
Schistosoma mansoni tyrosine kinase 0.0021 0.0018 0.0027
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.0405 0.1655
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0366 0.0538
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0018 0.0041
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0175 0.0393
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0366 0.0538
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.024 0.024
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0653 0.4439 0.9983
Echinococcus granulosus c src tyrosine kinase 0.0021 0.0018 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0071 0.0366 0.1068
Loa Loa (eye worm) glutaminase 2 0.0265 0.1724 0.1724
Loa Loa (eye worm) hypothetical protein 0.0053 0.024 0.024
Brugia malayi Latrophilin receptor protein 2 0.0458 0.3076 0.3076
Brugia malayi TAR-binding protein 0.0654 0.4447 0.4447
Schistosoma mansoni tar DNA-binding protein 0.0654 0.4447 0.6544
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.004 0.015 0.0221
Loa Loa (eye worm) steroid hormone receptor 0.0053 0.024 0.024
Schistosoma mansoni isocitrate dehydrogenase 0.004 0.015 0.0221
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0045 0.01
Brugia malayi glutaminase DH11.1 0.0265 0.1724 0.1724
Loa Loa (eye worm) MH2 domain-containing protein 0.1247 0.8589 0.8589
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0053 0.024 0.0352
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.024 0.0539
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.0405 0.1618
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0329 0.217 0.3194
Loa Loa (eye worm) hypothetical protein 0.0053 0.024 0.024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.024 0.0352
Brugia malayi beta-lactamase 0.0043 0.0175 0.0175
Echinococcus multilocularis conserved hypothetical protein 0.006 0.029 0.0652
Echinococcus granulosus ecdysone induced protein 78C 0.0053 0.024 0.0539
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.024 0.024
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0045 0.01
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0021 0.0018 0.0041
Toxoplasma gondii LsmAD domain-containing protein 0.0182 0.1141 0.5134
Brugia malayi photoreceptor-specific nuclear receptor 0.0287 0.1879 0.1879
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0053 0.024 0.024
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0053 0.024 0.024
Brugia malayi nuclear receptor NHR-88 0.0025 0.0045 0.0045
Brugia malayi MH2 domain containing protein 0.0038 0.0136 0.0136
Brugia malayi Calcitonin receptor-like protein seb-1 0.1449 1 1
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0081 0.044 0.099
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0244 0.0548
Schistosoma mansoni hypothetical protein 0.0458 0.3076 0.4526
Schistosoma mansoni hypothetical protein 0.0458 0.3076 0.4526
Echinococcus granulosus Glycosyl transferase family 8 0.0081 0.0436 0.0979
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0244 0.0359
Echinococcus granulosus smad 0.0085 0.0465 0.1045
Loa Loa (eye worm) hypothetical protein 0.0025 0.0045 0.0045
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0053 0.024 0.0539
Echinococcus granulosus geminin 0.0198 0.1252 0.2816
Plasmodium falciparum phd finger protein, putative 0.0035 0.0117 0.0294
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0175 0.0157
Echinococcus multilocularis peregrin 0.0035 0.0117 0.0263
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0081 0.044 0.099
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0175 0.3429
Schistosoma mansoni hypothetical protein 0.0198 0.1252 0.1843
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0324 0.2136 0.4804
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0175 0.0122
Schistosoma mansoni hypothetical protein 0.0198 0.1252 0.1843
Brugia malayi PHD-finger family protein 0.0035 0.0117 0.0117
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0458 0.3076 0.6917
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0175 0.0157
Loa Loa (eye worm) glycosyl transferase family 8 protein 0.0081 0.0436 0.0436
Schistosoma mansoni smad1 5 8 and 0.0085 0.0465 0.0684

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 26.6795 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 112.2018 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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