Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | amine GPCR | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | g protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | Inositol-1 | 0.0036 | 0.0777 | 0.0777 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.002 | 0.0036 | 0.0036 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0777 | 0.577 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Brugia malayi | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | larval opioid receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | amine GPCR | 0.002 | 0.0036 | 0.0036 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.078 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0645 | 0.0645 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0033 | 0.0645 | 0.0645 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0072 | 0.2385 | 0.2385 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0021 | 0.0095 | 0.1221 |
Echinococcus granulosus | allatostatin A receptor | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | neuropeptides capa receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | histamine h1 receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.512 | 0.512 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0645 | 0.0645 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.0777 | 0.0777 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.0777 | 0.0777 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.078 | 0.078 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0242 | 1 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.0095 | 0.1565 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.512 | 0.512 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0106 | 0.3884 | 0.3884 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.0095 | 0.1221 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0242 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.512 | 0.512 |
Brugia malayi | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | RNA binding protein | 0.0133 | 0.512 | 0.512 |
Brugia malayi | ORL1-like opioid receptor | 0.002 | 0.0036 | 0.0036 |
Leishmania major | DNA polymerase eta, putative | 0.0034 | 0.0693 | 0.5143 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | tar DNA binding protein | 0.0133 | 0.512 | 0.512 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0049 | 0.1348 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.512 | 0.512 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | serotonin receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | opsin-like receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | dna polymerase kappa | 0.0021 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.002 | 0.0036 | 0.0036 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.0606 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.2385 | 0.2385 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.4353 | 0.4353 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0034 | 0.0693 | 0.5143 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | amine GPCR | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0242 | 1 | 1 |
Brugia malayi | Serotonin receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | RNA binding protein | 0.0133 | 0.512 | 0.512 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0133 | 0.512 | 0.512 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0645 | 0.0645 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0095 | 0.0095 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0133 | 0.512 | 0.512 |
Brugia malayi | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | neuropeptide receptor | 0.002 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Trypanosoma brucei | unspecified product | 0.0021 | 0.0095 | 0.0705 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0645 | 0.0645 |
Schistosoma mansoni | myosin xvIII | 0.002 | 0.0036 | 0.0036 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0645 | 0.0645 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.002 | 0.0036 | 0.0036 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | somatostatin receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0049 | 0.1348 | 0.1348 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.2385 | 0.2385 |
Echinococcus granulosus | neuropeptide receptor | 0.002 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0242 | 1 | 1 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.078 | 1 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.002 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0095 | 0.0705 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0033 | 0.0645 | 0.0645 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0034 | 0.0693 | 0.8915 |
Brugia malayi | G-protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0777 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.002 | 0.0036 | 0.0036 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0033 | 0.0645 | 0.0645 |
Brugia malayi | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0033 | 0.0645 | 0.0645 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | opsin-like receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | GPCR family 2 | 0.0033 | 0.0645 | 0.0645 |
Schistosoma mansoni | biogenic amine receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | TAR-binding protein | 0.0133 | 0.512 | 0.512 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | TAR-binding protein | 0.0133 | 0.512 | 0.512 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | Melatonin receptor type 1A | 0.002 | 0.0036 | 0.0036 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Brugia malayi | neuropeptide F receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0021 | 0.0095 | 0.0095 |
Brugia malayi | Dopamine receptor protein 1 | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0095 | 0.0705 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | sex peptide receptor | 0.002 | 0.0036 | 0.0036 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0777 | 0.577 |
Brugia malayi | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0242 | 1 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.002 | 0.0036 | 0.0036 |
Leishmania major | DNA polymerase eta, putative | 0.0049 | 0.1348 | 1 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.002 | 0.0036 | 0.0036 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0777 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.0095 | 0.1221 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0095 | 0.0705 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.3884 | 0.3884 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | g-protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | GPCR, family 2 | 0.0033 | 0.0645 | 0.0645 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.078 | 0.078 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.002 | 0.0036 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.512 | 0.512 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0645 | 0.0645 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.002 | 0.0036 | 0.0036 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.078 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | g protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0021 | 0.0095 | 0.1221 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.002 | 0.0036 | 0.0036 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.0777 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | putative neuropeptide receptor | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | dna polymerase eta | 0.0049 | 0.1348 | 0.1348 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.078 | 0.078 |
Schistosoma mansoni | biogenic amine receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | neuropeptide s receptor | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | hypothetical protein | 0.0036 | 0.078 | 0.078 |
Echinococcus multilocularis | dna polymerase eta | 0.0049 | 0.1348 | 0.1348 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | RE15519p | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | neuropeptides capa receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.002 | 0.0036 | 0.0036 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.0095 | 0.1565 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0777 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.4353 | 0.4353 |
Echinococcus granulosus | g-protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | fmrfamide receptor | 0.002 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Brugia malayi | Dopamine receptor protein 2 | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | allatostatin A receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | orexin receptor type 2 | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | serotonin receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | amine GPCR | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0242 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0242 | 1 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0021 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | g protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.002 | 0.0036 | 0.0036 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0095 | 0.0705 |
Schistosoma mansoni | opsin-like receptor | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | Serotonin receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | amine GPCR | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | neuropeptide Y receptor | 0.002 | 0.0036 | 0.0036 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0777 | 0.577 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0645 | 0.0645 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | AKH receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | g protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | adenoreceptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.002 | 0.0036 | 0.0036 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0021 | 0.0095 | 0.1218 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0777 | 0.0777 |
Echinococcus granulosus | tar DNA binding protein | 0.0133 | 0.512 | 0.512 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Schistosoma mansoni | neuropeptide receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | fmrfamide receptor | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0106 | 0.3884 | 0.3884 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0095 | 0.0095 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.002 | 0.0036 | 0.0036 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0777 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.0777 | 0.0777 |
Brugia malayi | neuropeptide F receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | sex peptide receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.4353 | 0.4353 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | neuropeptide s receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | g protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | somatostatin receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | DNA polymerase eta | 0.0049 | 0.1348 | 0.1348 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.002 | 0.0036 | 0.0036 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.078 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0021 | 0.0095 | 0.0095 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.0777 | 0.0777 |
Echinococcus multilocularis | neuropeptide receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | neuropeptide receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | follicle stimulating hormone receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.002 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Echinococcus granulosus | dro:myosuppressin receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | G protein-coupled receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.078 | 0.078 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Schistosoma mansoni | neuropeptide receptor | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | G-protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | orexin receptor type 2 | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0106 | 0.3884 | 0.3884 |
Brugia malayi | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.002 | 0.0036 | 0.0036 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.0777 | 0.9971 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1348 | 0.1348 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0606 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.002 | 0.0036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0242 | 1 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0033 | 0.0645 | 0.0645 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.002 | 0.0036 | 0.0036 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0777 | 0.577 |
Schistosoma mansoni | neuropeptide receptor | 0.002 | 0.0036 | 0.0036 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Echinococcus multilocularis | serotonin receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.0095 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.002 | 0.0036 | 0.0036 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.002 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | sulfakinin receptor protein | 0.002 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.002 | 0.0036 | 0.5 | |
Brugia malayi | Dopamine receptor | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | g protein coupled receptor | 0.002 | 0.0036 | 0.0036 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.0777 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.002 | 0.0036 | 0.0036 |
Brugia malayi | hypothetical protein | 0.002 | 0.0036 | 0.0036 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Brugia malayi | GnHR receptor homolog | 0.002 | 0.0036 | 0.0036 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.002 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.002 | 0.0036 | 0.0036 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0021 | 0.0095 | 0.0095 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0095 | 0.0705 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0049 | 0.1348 | 1 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.002 | 0.0036 | 0.0036 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 25 uM | In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | ChEMBL. | 15115404 |
IC50 (binding) | = 25 uM | In vitro inhibition of sirtuin 2 was evaluated using yeast whole cell lysates | ChEMBL. | 15115404 |
MGC (binding) | >= 150 uM | Sirtuin 2 inhibitory activity and was reported as minimum growth-stimulating concentration in S. cerevisiae | ChEMBL. | 15115404 |
MGC (binding) | >= 150 uM | Sirtuin 2 inhibitory activity and was reported as minimum growth-stimulating concentration in S. cerevisiae | ChEMBL. | 15115404 |
T1/2 (ADMET) | = 13 hr | Half-life period of the compound was determined | ChEMBL. | 15115404 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.