Detailed information for compound 1460211

Basic information

Technical information
  • TDR Targets ID: 1460211
  • Name: 1,3-dimethyl-5-[1-(oxolan-2-ylmethylamino)eth ylidene]-1,3-diazinane-2,4,6-trione
  • MW: 281.308 | Formula: C13H19N3O4
  • H donors: 1 H acceptors: 3 LogP: 0.8 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1N(C)C(=O)C(=C(NCC2CCCO2)C)C(=O)N1C
  • InChi: 1S/C13H19N3O4/c1-8(14-7-9-5-4-6-20-9)10-11(17)15(2)13(19)16(3)12(10)18/h9,14H,4-7H2,1-3H3
  • InChiKey: VZQIZMKHUZTELQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1,3-dimethyl-5-[1-(tetrahydrofuran-2-ylmethylamino)ethylidene]hexahydropyrimidine-2,4,6-trione
  • 1,3-dimethyl-5-[1-(2-tetrahydrofuranylmethylamino)ethylidene]hexahydropyrimidine-2,4,6-trione
  • 1,3-dimethyl-5-[1-(tetrahydrofurfurylamino)ethylidene]barbituric acid
  • MLS000040954
  • SMR000043925
  • STOCK4S-25799

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.002 0.0042 0.0296
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.005 0.005
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.2918 0.9991 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0025 0.0058 0.0058
Echinococcus granulosus dna polymerase eta 0.0017 0.0032 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0034 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.004 0.004
Echinococcus multilocularis cpg binding protein 0.0036 0.0097 0.0097
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0034 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0022 0.005 0.005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.005 0.005
Trichomonas vaginalis heat shock protein, putative 0.0016 0.0027 0.0027
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0042 0.0042
Schistosoma mansoni cpg binding protein 0.0036 0.0097 0.0097
Echinococcus granulosus cathepsin l1 0.0013 0.0019 0.0019
Loa Loa (eye worm) nuclear receptor NHR-67 0.0027 0.0065 0.0065
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0052 0.0052
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Echinococcus multilocularis dna polymerase eta 0.0017 0.0032 0.0032
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.2918 0.9991 1
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0052 0.0052
Echinococcus multilocularis 0.0513 0.1734 0.1734
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0416 0.1403 1
Trypanosoma brucei heat shock protein, putative 0.0038 0.0104 0.0104
Schistosoma mansoni DNA polymerase eta 0.0017 0.0032 0.0032
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0416 0.1403 0.1404
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0056 0.0167 0.0167
Schistosoma mansoni ferritin light chain 0.001 0.0008 0.0007
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.003 0.0077 0.0551
Mycobacterium tuberculosis Possible two component sensor kinase 0.0008 0.0000088986 0.0001
Schistosoma mansoni organic anion transporter 0.0033 0.0085 0.0085
Schistosoma mansoni intermediate filament proteins 0.0032 0.0083 0.0083
Schistosoma mansoni heat shock protein 0.0038 0.0104 0.0104
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0098 0.0098
Brugia malayi nuclear hormone receptor family member odr-7 0.0027 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0023 0.0052 0.0052
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0419 0.1412 0.1412
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0008 0.0000088986 0.0001
Echinococcus multilocularis 0.0008 0.0002 0.0002
Onchocerca volvulus 0.002 0.0042 0.0296
Echinococcus multilocularis serine protein kinase ATM 0.001 0.0008 0.0008
Brugia malayi Cytochrome P450 family protein 0.0029 0.0072 0.0072
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.005 0.005
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.005 0.005
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0341 0.1145 0.1145
Loa Loa (eye worm) hypothetical protein 0.0336 0.1128 0.1129
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0016 0.0027 0.0191
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0042
Onchocerca volvulus 0.0022 0.005 0.0354
Loa Loa (eye worm) hypothetical protein 0.0033 0.0085 0.0085
Schistosoma mansoni apoferritin-2 0.001 0.0008 0.0007
Onchocerca volvulus Putative organic anion transporter 0.0033 0.0085 0.0607
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0008 0.0002 0.0014
Loa Loa (eye worm) heat shock protein 90 0.0038 0.0104 0.0104
Echinococcus multilocularis cathepsin L 0.001 0.0009 0.0009
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0416 0.1403 0.1404
Schistosoma mansoni heat shock protein 0.0038 0.0104 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0007 0.0007
Schistosoma mansoni ferritin 0.001 0.0008 0.0007
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0052 0.0051
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0416 0.1403 1
Brugia malayi hypothetical protein 0.0023 0.0052 0.0052
Toxoplasma gondii cytochrome p450 superfamily protein 0.0008 0.0002 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0009 0.0009
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.2918 0.9991 0.9998
Schistosoma mansoni ferritin 0.001 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0008 0.0002 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0052 0.0052
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0008 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0027 0.0065 0.0065
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.2918 0.9991 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Trypanosoma cruzi heat shock protein 85, putative 0.0038 0.0104 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0071
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0007 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0416 0.1403 0.1404
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.005 0.005
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0008 0.0002 0.0002
Plasmodium vivax vivapain-2 0.002 0.0042 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0108 0.0108
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.005 0.0357
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0008 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Toxoplasma gondii heat shock protein 90, putative 0.0038 0.0104 0.074
Echinococcus granulosus microtubule associated protein 2 0.0819 0.2783 0.2783
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0123 0.0875
Loa Loa (eye worm) endoplasmin 0.0038 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0022 0.005 0.005
Treponema pallidum heat shock protein 90 0.003 0.0077 0.0077
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0052 0.0051
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0042 0.0042
Trypanosoma cruzi target of rapamycin kinase 3 0.0042 0.0117 0.0117
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.001 0.0008 0.0008
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.0065 0.0462
Trypanosoma cruzi cysteine proteinase, putative 0.001 0.0009 0.0009
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0056 0.0167 0.0167
Schistosoma mansoni ferritin 0.001 0.0008 0.0007
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0416 0.1403 0.1404
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0053 0.0154 0.0154
Echinococcus granulosus heat shock protein 90 0.0038 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Schistosoma mansoni lamin 0.0032 0.0083 0.0083
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0056 0.0167 0.0167
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0341 0.1145 0.1145
Leishmania major cathepsin L-like protease 0.0076 0.0233 0.0233
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0072 0.0072
Loa Loa (eye worm) cytochrome P450 0.0008 0.0002 0.0002
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0008 0.0000088986 0.0001
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.005 0.005
Trypanosoma cruzi heat shock protein 90, putative 0.0038 0.0104 0.0104
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0083 0.0083
Mycobacterium ulcerans heat shock protein 90 0.003 0.0077 0.0077
Trichomonas vaginalis fk506-binding protein, putative 0.0416 0.1403 0.1404
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0416 0.1403 0.1404
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0008 0.0002 0.0014
Schistosoma mansoni hypothetical protein 0.006 0.0181 0.0181
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0416 0.1403 0.1404
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Onchocerca volvulus 0.002 0.0042 0.0296
Mycobacterium ulcerans hypothetical protein 0.0513 0.1734 0.1736
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0056 0.0167 0.0167
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0027 0.0065 0.0065
Entamoeba histolytica cysteine proteinase 2 0.001 0.0009 0.0009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.0167 0.0167
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.2918 0.9991 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0034 0.0034
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0009 0.0009
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0052 0.0051
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0416 0.1403 0.1404
Echinococcus granulosus ferritin 0.001 0.0008 0.0007
Brugia malayi CXXC zinc finger family protein 0.0034 0.009 0.009
Loa Loa (eye worm) hypothetical protein 0.0033 0.0085 0.0085
Leishmania major heat shock protein, putative 0.0016 0.0027 0.0027
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Plasmodium falciparum serine/threonine protein phosphatase 2B catalytic subunit A 0.0341 0.1145 0.1146
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.003 0.0077 0.0551
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0233 0.0233
Brugia malayi photoreceptor-specific nuclear receptor 0.0056 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0023 0.0052 0.0052
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.2918 0.9991 1
Trichomonas vaginalis spliceosomal protein sap, putative 0.0033 0.0085 0.0085
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0008 0.0002 0.0002
Onchocerca volvulus 0.002 0.0042 0.0296
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Trichomonas vaginalis fk506-binding protein, putative 0.0416 0.1403 0.1404
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.003 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.0399 0.1343 0.1343
Loa Loa (eye worm) hypothetical protein 0.0043 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.003 0.0076 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0091 0.0091
Onchocerca volvulus 0.0056 0.0167 0.119
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0416 0.1403 0.1404
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.001 0.0009 0.0009
Entamoeba histolytica cysteine proteinase 1, putative 0.001 0.0009 0.0009
Brugia malayi hypothetical protein 0.0027 0.0065 0.0065
Trypanosoma cruzi cysteine protease, putative 0.001 0.0009 0.0009
Brugia malayi cytochrome P450 0.0008 0.0002 0.0002
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0033 0.0085 0.0085
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0098 0.0098
Onchocerca volvulus 0.0282 0.0941 0.6693
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0052 0.0051
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Brugia malayi sodium-independent organic anion transporter family protein 0.0033 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0399 0.1343 0.1343
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0014 0.0014
Trypanosoma brucei heat shock protein, putative 0.0038 0.0104 0.0104
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.005 0.0355
Loa Loa (eye worm) fibroinase 0.002 0.0042 0.0042
Brugia malayi hypothetical protein 0.003 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0108 0.0108
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.2921 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0052 0.0051
Echinococcus granulosus cpg binding protein 0.0036 0.0097 0.0097
Onchocerca volvulus 0.0416 0.1403 0.9984
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0065 0.0065
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0008 0.0000088986 0.0001
Schistosoma mansoni cpg binding protein 0.0036 0.0097 0.0097
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0008 0.0002 0.0002
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0017 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0024
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Mycobacterium tuberculosis Conserved protein 0.0043 0.0123 0.0875
Giardia lamblia Hypothetical protein 0.0416 0.1403 0.1404
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0416 0.1403 0.1404
Onchocerca volvulus 0.0013 0.0019 0.0136
Schistosoma mansoni nuclear receptor 0.0027 0.0065 0.0065
Toxoplasma gondii cathepsin CPL 0.002 0.0042 0.0297
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0008 0.0002 0.0014
Onchocerca volvulus 0.0033 0.0085 0.0607
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0022 0.005 0.005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.002 0.0044 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0052 0.0052
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0008 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0042 0.0042
Echinococcus multilocularis cysteine protease 0.002 0.0042 0.0042
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.005 0.0355
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.2918 0.9991 1
Echinococcus granulosus endoplasmin 0.003 0.0077 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0108 0.0108
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0341 0.1145 0.1145
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0056 0.0167 0.0167
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0123 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0034 0.0034
Entamoeba histolytica hypothetical protein 0.0023 0.0052 0.0051
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0154 0.0154
Loa Loa (eye worm) cysteine protease 0.002 0.0042 0.0042
Schistosoma mansoni immunophilin 0.2505 0.8571 0.8571
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0033 0.0085 0.0085
Onchocerca volvulus 0.0032 0.0083 0.0593
Trypanosoma brucei heat shock protein 90, putative 0.0038 0.0104 0.0104
Schistosoma mansoni protein phosphatase-2b 0.0341 0.1145 0.1145
Onchocerca volvulus 0.0027 0.0065 0.0462
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0056 0.0167 0.0167
Entamoeba histolytica calcineurin catalytic subunit A, putative 0.0341 0.1145 0.1145
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0042 0.0042
Echinococcus granulosus dna polymerase kappa 0.0048 0.0138 0.0138
Echinococcus multilocularis heat shock protein 0.0038 0.0104 0.0104
Plasmodium vivax vivapain-3 0.001 0.0009 0.0009
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0056 0.0167 0.119
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0123 0.0875
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0042 0.0042
Onchocerca volvulus 0.0027 0.0065 0.0462
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0123 0.0123
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0083 0.0083
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.005 0.005
Trichomonas vaginalis receptor histidine kinase, putative 0.0008 0.0000088986 0.0000055986
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0008 0.0002 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Brugia malayi sodium-independent organic anion transporter family protein 0.0033 0.0085 0.0085
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0081 0.0081
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0052 0.0052
Loa Loa (eye worm) nuclear hormone receptor 0.0027 0.0065 0.0065
Brugia malayi Serine/threonine protein phosphatase 2B catalytic subunit 2 0.0341 0.1145 0.1145
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.004 0.004
Loa Loa (eye worm) heat shock protein 75 0.0016 0.0027 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0108 0.0108
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0053 0.0154 0.0154
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Mycobacterium ulcerans beta-lactamase 0.0043 0.0123 0.0123
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0154 0.0154
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0008 0.0000088986 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0008 0.0008
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0017 0.0032 0.0032
Entamoeba histolytica protein kinase rad3, putative 0.001 0.0008 0.0008
Onchocerca volvulus 0.0036 0.0098 0.0694
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0056 0.0167 0.0167
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.003 0.0077 0.0551
Loa Loa (eye worm) steroid hormone receptor 0.0056 0.0167 0.0167
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0034 0.0034
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0416 0.1403 0.1404
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0056 0.0167 0.0167
Toxoplasma gondii Hsp90 domain-containing protein 0.0016 0.0027 0.0192
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0032 0.0083 0.0083
Schistosoma mansoni endoplasmin 0.0038 0.0104 0.0104
Echinococcus multilocularis ferritin 0.001 0.0008 0.0007
Echinococcus granulosus cathepsin L 0.001 0.0009 0.0009
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0008 0.0002 0.0002
Trypanosoma brucei cytochrome P450, putative 0.0029 0.0072 0.0072
Echinococcus granulosus cytochrome P450 2K1 0.0008 0.0002 0.0002
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0011 0.0012 0.0082
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0008 0.0002 0.0002
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0014 0.0014
Trichomonas vaginalis ferritin, putative 0.001 0.0008 0.0008
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0008 0.0000088986 0.0000055986
Plasmodium vivax splicing factor 3B subunit 3, putative 0.0033 0.0085 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Leishmania major serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0341 0.1145 0.1146
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.001 0.0009 0.0009
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0056 0.0167 0.0167
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0123 0.0875
Brugia malayi hypothetical protein 0.0033 0.0085 0.0085
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0042 0.0117 0.0117
Echinococcus multilocularis lamin 0.0032 0.0083 0.0083
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0052 0.0052
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.2918 0.9991 1
Brugia malayi conserved hypotetical protein 0.0027 0.0065 0.0065
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.02 0.1422
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0513 0.1734 0.1736
Brugia malayi Hsp90 protein 0.0016 0.0027 0.0027
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0008 0.0000088986 0.0000055986
Mycobacterium leprae putative cytochrome p450 0.0008 0.0002 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0015 0.0027 0.0026
Toxoplasma gondii FATC domain-containing protein 0.001 0.0008 0.0054
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0014 0.0014
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0416 0.1403 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0017 0.0032 0.0032
Onchocerca volvulus Bile acid receptor homolog 0.0056 0.0167 0.119
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0513 0.1734 0.1734
Trichomonas vaginalis endoplasmin, putative 0.0023 0.0054 0.0054
Toxoplasma gondii heat shock protein HSP90 0.0038 0.0104 0.074
Trypanosoma brucei hypothetical protein, conserved 0.0416 0.1403 0.1404
Brugia malayi nuclear hormone receptor family member nhr-6 0.0027 0.0065 0.0065
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0052 0.0051
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0123 0.0123
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0008 0.0000088986 0.0000055986
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.005 0.0355
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.003 0.0076 0.0076
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0025 0.0058 0.0414
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0034 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0127 0.0128
Echinococcus multilocularis agrin 0.0022 0.005 0.005
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0043 0.0123 0.0123
Schistosoma mansoni zinc finger protein 0.0027 0.0065 0.0065
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0016 0.0027 0.0027
Echinococcus multilocularis heat shock protein 90 0.0038 0.0104 0.0104
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0056 0.0167 0.0167
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.2921 1 1
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0052 0.0051
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0513 0.1734 0.1736
Leishmania major DNA polymerase eta, putative 0.0017 0.0032 0.0032
Onchocerca volvulus 0.002 0.0042 0.0296
Schistosoma mansoni terminal deoxycytidyl transferase 0.0017 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0008 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Plasmodium vivax vivapain-1 0.001 0.0009 0.0009
Brugia malayi nuclear hormone receptor 0.0027 0.0065 0.0065
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.0167 0.0167
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.005 0.005
Trypanosoma cruzi cruzipain precursor, putative 0.0076 0.0233 0.0233
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0052 0.0052
Trypanosoma cruzi Heat shock protein 83, putative 0.0038 0.0104 0.0104
Schistosoma mansoni nuclear receptor 0.0027 0.0065 0.0065
Brugia malayi Cathepsin L-like precursor 0.0013 0.0019 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.0167 0.0167
Trichomonas vaginalis fk506-binding protein, putative 0.2918 0.9991 1
Echinococcus granulosus splicing factor 3b subunit 3 0.0033 0.0085 0.0085
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0053 0.0154 0.0154
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0042 0.0042
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0042 0.0042
Loa Loa (eye worm) CXXC zinc finger family protein 0.0034 0.009 0.009
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0053 0.0154 0.0154
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0052 0.0052
Mycobacterium tuberculosis Conserved protein 0.0043 0.0123 0.0875
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0042
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0008 0.0000088986 0.0001
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0008 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Trichomonas vaginalis DNA topoisomerase II, putative 0.0008 0.0000088986 0.0000055986
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0149 0.0486 0.0486
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0033 0.0085 0.0085
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0008 0.0000088986 0.0001
Plasmodium vivax heat shock protein, putative 0.0016 0.0027 0.0027
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0065 0.0065
Echinococcus multilocularis cysteine protease 0.002 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0019
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0053 0.0154 0.0154
Brugia malayi cathepsin L-like precursor 0.0013 0.0019 0.0019
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0123 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0052 0.0052
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.001 0.0008 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0098 0.0098
Echinococcus granulosus heat shock protein 90 0.003 0.0077 0.0077
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0048 0.0048
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Leishmania major DNA polymerase kappa, putative 0.0025 0.0058 0.0058
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0008 0.0000088986 0.0000055986
Leishmania major hypothetical protein, conserved 0.0043 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0009 0.0009
Loa Loa (eye worm) CYP4Cod1 0.0029 0.0072 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0056 0.0167 0.0167
Brugia malayi nuclear receptor RXR 0.0027 0.0065 0.0065
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0009 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0098 0.0098
Schistosoma mansoni RAR-like nuclear receptor 0.0056 0.0167 0.0167
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0008 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.001 0.0008 0.0053
Trypanosoma brucei heat shock protein, putative 0.0038 0.0104 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0154 0.0154
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0032 0.0032
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0009 0.0009
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.001 0.0009 0.0009
Echinococcus granulosus thyroid hormone receptor alpha 0.0027 0.0065 0.0065
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0416 0.1403 0.1404
Loa Loa (eye worm) hypothetical protein 0.003 0.0076 0.0076
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0033 0.0085 0.0085
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0016 0.0027 0.0027
Trypanosoma cruzi MFS transporter, putative 0.0033 0.0085 0.0085
Echinococcus granulosus cysteine protease 0.001 0.0009 0.0009
Trichomonas vaginalis heat shock protein, putative 0.003 0.0077 0.0077
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.005 0.0357
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0513 0.1734 0.1736
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Onchocerca volvulus 0.0033 0.0085 0.0607
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.005 0.005
Trypanosoma cruzi heat shock protein 90, putative 0.0022 0.005 0.005
Trichomonas vaginalis heat shock protein, putative 0.0038 0.0104 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Trichomonas vaginalis heat shock protein, putative 0.003 0.0077 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0056 0.0167 0.0167
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.001 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0029 0.0072 0.0072
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0008 0.0002 0.0014
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.005 0.005
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0008 0.0002 0.0002
Echinococcus multilocularis dnaJ subfamily B 0.0485 0.1639 0.1639
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0042 0.0042
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.2921 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0071
Trypanosoma brucei heat shock protein, putative 0.0038 0.0104 0.0104
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0022 0.005 0.005
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0008 0.0002 0.0014
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0008 0.0002 0.0002
Leishmania major cathepsin L-like protease 0.002 0.0042 0.0042
Echinococcus granulosus follistatin 0.0022 0.005 0.005
Entamoeba histolytica hypothetical protein 0.001 0.0008 0.0008
Mycobacterium ulcerans bacterioferritin BfrA 0.001 0.0008 0.0007
Brugia malayi nuclear receptor NHR-88 0.0056 0.0167 0.0167
Schistosoma mansoni nuclear hormone receptor 0.0056 0.0167 0.0167
Schistosoma mansoni coup transcription factor 0.0056 0.0167 0.0167
Mycobacterium ulcerans esterase/lipase LipP 0.0043 0.0123 0.0123
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0341 0.1145 0.1145
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0008 0.0000088986 0.0001
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0416 0.1403 0.1404
Trypanosoma brucei Heat shock protein 83, putative 0.0038 0.0104 0.0104
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Schistosoma mansoni microtubule-associated protein tau 0.0819 0.2783 0.2783
Onchocerca volvulus 0.002 0.0042 0.0296
Schistosoma mansoni ferritin 0.001 0.0008 0.0007
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.001 0.0008 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0233 0.0233
Mycobacterium tuberculosis Conserved protein 0.0008 0.0000088986 0.0001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0123 0.0123
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0341 0.1145 0.1145
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0416 0.1403 0.1404
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0117 0.0117
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0032 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Onchocerca volvulus 0.0043 0.0123 0.0873
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0019
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.2918 0.9991 1
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0052 0.0051
Plasmodium vivax unspecified product 0.001 0.0009 0.0009
Schistosoma mansoni agrin 0.0022 0.005 0.005
Mycobacterium tuberculosis Probable two component sensor kinase 0.0008 0.0000088986 0.0001
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0042 0.0042
Trypanosoma brucei heat shock protein, putative 0.0038 0.0104 0.0104
Trypanosoma cruzi heat shock protein, putative 0.0016 0.0027 0.0027
Toxoplasma gondii protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein 0.0341 0.1145 0.8159
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0083 0.0083
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0149 0.0486 0.0486
Loa Loa (eye worm) hypothetical protein 0.0011 0.0012 0.0011
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0042
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0056 0.0167 0.0167
Onchocerca volvulus 0.0032 0.0083 0.0593
Onchocerca volvulus Putative organic anion transporter 0.0033 0.0085 0.0607
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0059 0.0059
Schistosoma mansoni cpg binding protein 0.0034 0.009 0.009
Echinococcus granulosus ecdysone induced protein 78C 0.0056 0.0167 0.0167
Brugia malayi orphan nuclear receptor NR2E1 0.0027 0.0065 0.0065
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.003 0.0077 0.0077
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0008 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0043 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0008 0.0002 0.0002
Brugia malayi SPARC precursor 0.0022 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.003 0.0076 0.0076
Brugia malayi nuclear receptor NHR-88 0.0027 0.0065 0.0065
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0033 0.0085 0.0085
Onchocerca volvulus Cathepsin L homolog 0.002 0.0042 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0056 0.0167 0.0167
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0008 0.0002 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0042 0.0042
Schistosoma mansoni retinoic acid receptor RXR 0.0056 0.0167 0.0167
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0008 0.0000088986 0.0000055986
Trichomonas vaginalis sensor histidine kinase, putative 0.0008 0.0000088986 0.0000055986
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0091 0.0091
Loa Loa (eye worm) hypothetical protein 0.0043 0.0123 0.0123
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0416 0.1403 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0008 0.0002 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0056 0.0167 0.0167
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0034 0.0034
Echinococcus multilocularis serine:threonine protein phosphatase 2B 0.0341 0.1145 0.1145
Toxoplasma gondii exonuclease III APE 0.0022 0.005 0.0357
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0008 0.0002 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0071
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0123 0.0123
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0053 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0036 0.0098 0.0098
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Leishmania major cysteine peptidase A (CPA) 0.002 0.0042 0.0042
Leishmania major cytochrome p450-like protein 0.0008 0.0002 0.0002
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0042 0.0042
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0027 0.0065 0.0065
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0416 0.1403 0.1403
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Schistosoma mansoni endoplasmin 0.0038 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0032 0.0032
Schistosoma mansoni immunophilin 0.2921 1 1
Toxoplasma gondii splicing factor 3b, subunit 3, putative 0.0033 0.0085 0.0608
Leishmania major cathepsin L-like protease 0.002 0.0042 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0071
Brugia malayi hypothetical protein 0.0023 0.0052 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0056 0.0167 0.0167
Brugia malayi Pre-SET motif family protein 0.0248 0.0823 0.0824
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0416 0.1403 0.1404
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0123 0.0123
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.003 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0033 0.0085 0.0085
Schistosoma mansoni organic anion transporter 0.0033 0.0085 0.0085
Brugia malayi beta-lactamase family protein 0.0043 0.0123 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0416 0.1403 0.1404
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0042 0.0042
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.001 0.0008 0.0008
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0027 0.0065 0.0462
Echinococcus granulosus serine:threonine protein kinase SMG1 0.001 0.0008 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.001 0.0009 0.0009
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0056 0.0167 0.0167
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0341 0.1145 0.1146
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0056 0.0167 0.0167
Toxoplasma gondii ABC1 family protein 0.0043 0.0123 0.0875
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0052 0.0051
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0023 0.0052 0.0052
Leishmania major fk506-binding protein 1-like protein 0.2918 0.9991 1
Schistosoma mansoni nuclear receptor nhr-48 0.0027 0.0065 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0094 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0007 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0042 0.0042
Onchocerca volvulus 0.002 0.0042 0.0296
Entamoeba histolytica deoxycytidyl transferase, putative 0.0017 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Trypanosoma cruzi major cysteine proteinase, putative 0.0059 0.0178 0.0178
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0008 0.0002 0.0014
Brugia malayi ImpB/MucB/SamB family protein 0.0017 0.0032 0.0032
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.003 0.0076 0.0076
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0052 0.0051
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.001 0.0008 0.0008
Trypanosoma cruzi serine/threonine protein phosphatase 2B catalytic subunit A2, putative 0.0341 0.1145 0.1146
Brugia malayi splicing factor 3B subunit 3 0.0033 0.0085 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0052 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0056 0.0167 0.0167
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0008 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0098 0.0098
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0513 0.1734 0.1736
Echinococcus multilocularis splicing factor 3b subunit 3 0.0033 0.0085 0.0085
Leishmania major cathepsin L-like protease 0.0076 0.0233 0.0233
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0008 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0033 0.0085 0.0085
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0019 0.0019
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.2918 0.9991 0.9991
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0056 0.0167 0.0167
Mycobacterium ulcerans DNA polymerase IV 0.0048 0.0138 0.0138
Echinococcus granulosus nuclear receptor nhr 48 0.0027 0.0065 0.0065
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.005 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0036 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0023 0.0052 0.0052
Entamoeba histolytica hypothetical protein 0.0023 0.0052 0.0051
Plasmodium vivax heat shock protein 90, putative 0.0016 0.0027 0.0027
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Mycobacterium ulcerans hypothetical protein 0.0043 0.0123 0.0123
Echinococcus granulosus cathepsin l1 0.002 0.0042 0.0042
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0053 0.0154 0.0154
Trypanosoma brucei DNA polymerase eta, putative 0.0017 0.0032 0.0032
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0013 0.0018 0.0128
Giardia lamblia Heat shock protein HSP 90-alpha 0.003 0.0077 0.0077
Echinococcus multilocularis expressed protein 0.001 0.0008 0.0007
Plasmodium falciparum heat shock protein 90 0.0038 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0065 0.0065
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0341 0.1145 0.1145
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0081 0.0081
Loa Loa (eye worm) ctsf protein 0.002 0.0042 0.0042
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0053 0.0154 0.0154
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0513 0.1734 0.1736
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Plasmodium falciparum heat shock protein 90, putative 0.0016 0.0027 0.0027
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0052 0.0051
Brugia malayi hypothetical protein 0.0027 0.0065 0.0065
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Entamoeba histolytica cysteine protease, putative 0.002 0.0042 0.0042
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0043 0.0123 0.0123
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0072 0.0072
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0416 0.1403 1
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0065 0.0065
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0056 0.0167 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0034 0.0034
Brugia malayi Pre-SET motif family protein 0.0036 0.0098 0.0098
Plasmodium falciparum endoplasmin, putative 0.0023 0.0054 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0056 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0012 0.0012
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.0027 0.0026
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0052 0.0051
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Entamoeba histolytica Ser/Thr protein phosphatase, putative 0.0341 0.1145 0.1145
Echinococcus granulosus lamin dm0 0.0032 0.0083 0.0083
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0008 0.0002 0.0014
Schistosoma mansoni ap endonuclease 0.0022 0.005 0.005
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.005 0.005
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0008 0.0002 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0123 0.0123
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.2918 0.9991 1
Schistosoma mansoni lamin 0.0032 0.0083 0.0083
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0052 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0052 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Trypanosoma brucei heat shock protein, putative 0.0038 0.0104 0.0104
Echinococcus granulosus dnaJ subfamily B 0.0485 0.1639 0.1639
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0123 0.0123
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0056 0.0167 0.0167
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0123 0.0875
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0052 0.0051
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0008 0.0002 0.0002
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0052 0.0051
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0233 0.0233
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0008 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.001
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0052 0.0051
Trypanosoma brucei unspecified product 0.004 0.0112 0.0112
Trichomonas vaginalis heat shock protein, putative 0.003 0.0077 0.0077
Mycobacterium leprae Probable lipase LipE 0.0043 0.0123 0.0875
Entamoeba histolytica heat shock protein 90, putative 0.0038 0.0104 0.0104
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.005 0.005
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0416 0.1403 0.1403
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.0072 0.0072
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0065 0.0065
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0048 0.0138 0.0138
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0008 0.0000088986 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0117 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0108 0.0108
Plasmodium vivax heat shock protein 86, putative 0.0038 0.0104 0.0104
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0008 0.0002 0.0014
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0042 0.0042
Echinococcus multilocularis ecdysone induced protein 78C 0.0056 0.0167 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0052 0.0051
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0053 0.0154 0.0154
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0416 0.1403 1
Mycobacterium tuberculosis Conserved protein 0.0043 0.0123 0.0875
Onchocerca volvulus 0.0034 0.009 0.0643
Echinococcus multilocularis dna polymerase kappa 0.0048 0.0138 0.0138
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0034 0.0034
Echinococcus granulosus FK506 binding protein 2 0.0513 0.1734 0.1734
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0416 0.1403 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0048 0.0138 0.0138
Schistosoma mansoni heat shock protein 0.0016 0.0027 0.0027
Trichomonas vaginalis fk506 binding protein, putative 0.0416 0.1403 0.1404
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0042 0.0042
Schistosoma mansoni apoferritin-2 0.001 0.0008 0.0007
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0076 0.0076
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0056 0.0167 0.0167
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0076 0.0076
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.0167 0.0167
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0123 0.0123
Schistosoma mansoni steroid hormone receptor ad4bp 0.0056 0.0167 0.0167
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0008 0.0002 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0025 0.0024
Echinococcus granulosus agrin 0.0022 0.005 0.005
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0248 0.0823 0.0824
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0416 0.1403 0.1404
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0052 0.0052
Echinococcus multilocularis FTZ F1 alpha 0.0056 0.0167 0.0167
Plasmodium falciparum splicing factor 3B subunit 3, putative 0.0033 0.0085 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0056 0.0167 0.0167
Echinococcus granulosus Solute carrier organic anion transporter family 0.0033 0.0085 0.0085
Echinococcus granulosus geminin 0.0399 0.1343 0.1343
Echinococcus granulosus expressed protein 0.001 0.0008 0.0007
Schistosoma mansoni fk506 binding protein 0.0416 0.1403 0.1403
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.2919 0.9993 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.004 0.004
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0056 0.0167 0.0167
Echinococcus granulosus expressed protein 0.0443 0.1493 0.1493
Leishmania major cathepsin L-like protease 0.002 0.0042 0.0042
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.2918 0.9991 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0056 0.0167 0.0167
Leishmania major cathepsin L-like protease 0.002 0.0042 0.0042
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0056 0.0167 0.0167
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0416 0.1403 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0017 0.0032 0.0032
Treponema pallidum bacterioferrin (TpF1) 0.001 0.0008 0.0007
Leishmania major peptidylprolyl isomerase-like protein 0.2918 0.9991 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0034 0.0034
Onchocerca volvulus 0.0033 0.0085 0.0607
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0056 0.0167 0.0167
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.003 0.0077 0.0077
Loa Loa (eye worm) DR-78 0.0027 0.0065 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0117 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.001 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0002 0.0002
Trypanosoma brucei DNA polymerase IV, putative 0.0048 0.0138 0.0138
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0065 0.0065
Loa Loa (eye worm) phosphatidylinositol 3 0.0053 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Schistosoma mansoni immunophilin 0.2921 1 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0098 0.0098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Loa Loa (eye worm) beta-lactamase 0.0043 0.0123 0.0123
Echinococcus multilocularis expressed protein 0.0022 0.005 0.005
Onchocerca volvulus 0.0043 0.0123 0.0873
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0042 0.0042
Toxoplasma gondii heat shock protein 75, putative 0.0016 0.0027 0.0192
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0008 0.0008
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.001 0.0008 0.0054
Loa Loa (eye worm) hypothetical protein 0.0043 0.0123 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0341 0.1145 0.1146
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0052 0.0051
Plasmodium vivax serine/threonine protein phosphatase 2B catalytic subunit A, putative 0.0341 0.1145 0.1146
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0098 0.0695
Schistosoma mansoni hypothetical protein 0.0416 0.1403 0.1403
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0023 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0033 0.0085 0.0085
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0008 0.0000088986 0.0001
Mycobacterium leprae Conserved hypothetical protein 0.0008 0.0002 0.0013
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0008 0.0002 0.0002
Echinococcus multilocularis lamin dm0 0.0032 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.2503 0.8564 0.8572
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0052 0.0051
Brugia malayi tailless protein 0.0027 0.0065 0.0065
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0056 0.0167 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.008 0.008
Trypanosoma cruzi heat shock protein 90, putative 0.003 0.0077 0.0077
Loa Loa (eye worm) FKBP5 protein 0.2918 0.9991 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0019 0.0019
Echinococcus multilocularis microtubule associated protein 2 0.0819 0.2783 0.2783
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0052 0.0051
Toxoplasma gondii target of rapamycin (TOR), putative 0.0039 0.0108 0.0766
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.2918 0.9991 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0052 0.0051
Onchocerca volvulus Putative organic anion transporter 0.0033 0.0085 0.0607
Trichomonas vaginalis esterase, putative 0.0043 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0056 0.0167 0.0167
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0069 0.0211 0.0211
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0123 0.0123
Trichomonas vaginalis immunophilin, putative 0.2918 0.9991 1
Giardia lamblia Grp94/Hsp90 0.003 0.0077 0.0077
Giardia lamblia Heat shock protein HSP 90-alpha 0.0038 0.0104 0.0104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0042 0.0042
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0008 0.0002 0.0002
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0019 0.0019
Toxoplasma gondii protease inhibitor PI2 0.0022 0.005 0.0355
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0065 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0008 0.0000088986 0.0001
Leishmania major cytochrome p450-like protein 0.0008 0.0002 0.0002
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.001 0.0008 0.0008
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0416 0.1403 0.1404
Toxoplasma gondii transporter, major facilitator family protein 0.0033 0.0085 0.0608
Brugia malayi nuclear receptor NHR-67 0.0027 0.0065 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0034 0.0034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.008 0.008
Schistosoma mansoni ferritin light chain 0.001 0.0008 0.0007
Trypanosoma brucei unspecified product 0.0012 0.0014 0.0013
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0022 0.005 0.0355
Brugia malayi prostaglandin transporter 0.0033 0.0085 0.0085
Brugia malayi PXA domain containing protein 0.0023 0.0052 0.0052
Brugia malayi heat shock protein 90 0.0038 0.0104 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Trichomonas vaginalis heat shock protein, putative 0.0023 0.0054 0.0054
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0034 0.0034
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0112 0.0112
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0042 0.0042
Echinococcus granulosus heat shock protein 0.0038 0.0104 0.0104
Onchocerca volvulus Cathepsin F homolog 0.002 0.0042 0.0296
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0042 0.0042
Echinococcus multilocularis heat shock protein 90 0.003 0.0077 0.0077
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0042 0.0042
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0416 0.1403 1
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0226 0.0226
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0108 0.0108
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.001 0.0008 0.0008
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0052 0.0051
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0123 0.0875
Trypanosoma brucei DNA polymerase IV, putative 0.0048 0.0138 0.0138
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0053 0.0154 0.0154
Echinococcus multilocularis geminin 0.0399 0.1343 0.1343
Brugia malayi Cytochrome P450 family protein 0.0008 0.0002 0.0002
Brugia malayi Cytochrome P450 family protein 0.0008 0.0002 0.0002
Plasmodium vivax endoplasmin, putative 0.0038 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0043 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.005 0.005
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0042 0.0042
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0027 0.0065 0.0065
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0123 0.0875
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0027 0.0065 0.0065
Trypanosoma cruzi cysteine proteinase, putative 0.001 0.0009 0.0009
Schistosoma mansoni thyroid hormone receptor 0.0206 0.068 0.068
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0008 0.0002 0.0014
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0416 0.1403 0.1404
Plasmodium falciparum cysteine proteinase falcipain 1 0.001 0.0009 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0056 0.0167 0.0167
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0056 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.003 0.0076 0.0076
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0052 0.0052
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0032 0.0225
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.2505 0.8571 0.8571
Entamoeba histolytica hypothetical protein 0.0023 0.0052 0.0051
Echinococcus granulosus FTZ F1 alpha 0.0056 0.0167 0.0167
Echinococcus granulosus cathepsin L cysteine protease 0.001 0.0009 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.0167 0.0167
Echinococcus granulosus intermediate filament protein 0.0032 0.0083 0.0083
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0056 0.0167 0.0167
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0123 0.0875
Trypanosoma cruzi heat shock protein 85, putative 0.0038 0.0104 0.0104
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0027 0.0065 0.0065
Onchocerca volvulus 0.0417 0.1405 1
Trypanosoma cruzi serine/threonine protein phosphatase, putative 0.0341 0.1145 0.1146
Trichomonas vaginalis receptor histidine kinase, putative 0.0008 0.0000088986 0.0000055986
Trypanosoma brucei heat shock protein 84, putative 0.0016 0.0027 0.0027
Trichomonas vaginalis set domain proteins, putative 0.0282 0.0941 0.0941
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0034 0.0034
Echinococcus granulosus serine:threonine protein phosphatase 2B 0.0341 0.1145 0.1145
Schistosoma mansoni fkbp-rapamycin associated protein 0.001 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0485 0.1639 0.1639
Brugia malayi Nuclear hormone receptor E75 0.0027 0.0065 0.0065
Plasmodium falciparum heat shock protein 90, putative 0.0016 0.0027 0.0027
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0027 0.0065 0.0065
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0027 0.0065 0.0065
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0117 0.0117
Brugia malayi PXA domain containing protein 0.0023 0.0052 0.0052
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0008 0.0002 0.0002
Brugia malayi ecdysteroid receptor 0.0056 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0022 0.005 0.005
Echinococcus multilocularis follistatin 0.0022 0.005 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0233 0.0233
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0052 0.0051
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0052 0.0052
Trypanosoma brucei unspecified product 0.0012 0.0014 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0117 0.0117
Trypanosoma cruzi heat shock protein 85, putative 0.0038 0.0104 0.0104
Entamoeba histolytica heat shock protein 90, putative 0.0038 0.0104 0.0104
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0053 0.0154 0.0154
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0008 0.0002 0.0014
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.0027 0.0026
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Trypanosoma brucei protein phosphatase 2B, putative 0.0341 0.1145 0.1146
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.005 0.005
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0008 0.0002 0.0014
Onchocerca volvulus 0.0043 0.0123 0.0873
Schistosoma mansoni ap endonuclease 0.0022 0.005 0.005
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.2918 0.9991 1
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0416 0.1403 0.1404
Brugia malayi sodium-independent organic anion transporter family protein 0.0033 0.0085 0.0085
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0042 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Echinococcus multilocularis nuclear receptor nhr 48 0.0027 0.0065 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0019 0.0019
Mycobacterium tuberculosis Bacterioferritin BfrB 0.001 0.0008 0.0054
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.005 0.005
Echinococcus multilocularis expressed protein 0.0443 0.1493 0.1493
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0042
Brugia malayi Endoplasmin precursor 0.0038 0.0104 0.0104
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Brugia malayi secreted modular calcium-binding protein 1 0.0022 0.005 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0071 0.0071
Leishmania major cytochrome p450-like protein 0.0029 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0056 0.0167 0.0167
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0052 0.0051
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0034 0.0034
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0022 0.005 0.005
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0052 0.0051
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0014 0.0014
Leishmania major cathepsin L-like protease 0.0076 0.0233 0.0233
Schistosoma mansoni cytochrome P450 0.0008 0.0002 0.0002
Trypanosoma brucei heat shock protein 90, putative 0.0038 0.0104 0.0104
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.2918 0.9991 1
Trypanosoma cruzi heat shock protein 85, putative 0.003 0.0077 0.0077
Brugia malayi ecdysone receptor 0.0027 0.0065 0.0065
Brugia malayi polk-prov protein 0.0036 0.0098 0.0098
Brugia malayi hypothetical protein 0.003 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0081 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0076 0.0076
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0108 0.0108
Leishmania major serine/threonine protein phosphatase, putative 0.0341 0.1145 0.1146
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0962 0.3275 0.3275
Trypanosoma brucei heat shock protein, putative 0.0038 0.0104 0.0104
Echinococcus multilocularis musashi 0.0032 0.0083 0.0083
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0042 0.0042
Brugia malayi steroid hormone receptor 0.0056 0.0167 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0081 0.0081
Brugia malayi nuclear hormone receptor 0.0056 0.0167 0.0167
Trypanosoma cruzi DNA polymerase kappa, putative 0.0048 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.0017 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0052 0.0052
Brugia malayi Papain family cysteine protease containing protein 0.001 0.0009 0.0009
Brugia malayi Cathepsin L-like precursor 0.002 0.0042 0.0042
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0008 0.0002 0.0002
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0052 0.0051
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.005 0.005
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0123 0.0123
Echinococcus granulosus lamin 0.0032 0.0083 0.0083
Schistosoma mansoni follistatin 0.0022 0.005 0.005
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009
Plasmodium vivax SET domain protein, putative 0.0036 0.0098 0.0098
Echinococcus multilocularis fk506 binding protein 0.2918 0.9991 0.9991
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0052 0.0051
Echinococcus multilocularis endoplasmin 0.003 0.0077 0.0077
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0052 0.0052
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0416 0.1403 0.1404
Brugia malayi Steroid receptor seven-up type 2 0.0056 0.0167 0.0167
Trypanosoma brucei heat shock protein, putative 0.0038 0.0104 0.0104
Echinococcus multilocularis thyroid hormone receptor alpha 0.0206 0.068 0.068
Brugia malayi intermediate filament protein 0.0032 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0033 0.0085 0.0085
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.001 0.0009 0.0009
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.0038 0.0104 0.0104
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.2918 0.9991 1
Echinococcus granulosus serine protein kinase ATM 0.001 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Schistosoma mansoni thyroid hormone receptor 0.0206 0.068 0.068
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0065
Brugia malayi beta-lactamase family protein 0.0043 0.0123 0.0123
Brugia malayi beta-lactamase 0.0043 0.0123 0.0123
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.2505 0.8571 0.8571
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.0927 0.6608
Schistosoma mansoni protein phosphatase-2b 0.0341 0.1145 0.1145
Giardia lamblia GTOR 0.0053 0.0154 0.0154
Mycobacterium ulcerans DNA polymerase IV 0.0048 0.0138 0.0138
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0042 0.0042
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0008 0.0002 0.0002
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0052 0.0051
Entamoeba histolytica cysteine proteinase, putative 0.001 0.0009 0.0009
Onchocerca volvulus 0.0033 0.0085 0.0607
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0008 0.0000088986 0.0001
Entamoeba histolytica CPSF A subunit region protein, putative 0.0033 0.0085 0.0085
Onchocerca volvulus Protein ultraspiracle homolog 0.0056 0.0167 0.119
Mycobacterium ulcerans bacterioferritin BfrB 0.001 0.0008 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0042 0.0042
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0042 0.0117 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0058 0.0058
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0008 0.0002 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0098 0.0098
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0056 0.0167 0.0167
Giardia lamblia DINP protein human, muc B family 0.0025 0.0058 0.0058
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.001 0.0008 0.0008
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0053 0.0154 0.0154
Brugia malayi hypothetical protein 0.0033 0.0085 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0042 0.0042
Leishmania major cathepsin L-like protease 0.002 0.0042 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0098 0.0098
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.2918 0.9991 0.9991
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0042 0.0042
Brugia malayi nuclear receptor RXR 0.003 0.0076 0.0076
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0016 0.0027 0.0027
Onchocerca volvulus 0.0033 0.0085 0.0607
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0123 0.0123
Onchocerca volvulus Cathepsin L homolog 0.002 0.0042 0.0296
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0098 0.0098
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0008 0.0002 0.0014
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0052 0.0051
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.005 0.005
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.2918 0.9991 1
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0042 0.0042
Loa Loa (eye worm) agrin synaptic family protein 0.0022 0.005 0.005
Echinococcus granulosus Nuclear hormone receptor HR96 0.0027 0.0065 0.0065
Schistosoma mansoni hypothetical protein 0.0149 0.0486 0.0486
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0416 0.1403 0.1404
Brugia malayi Cathepsin L-like precursor 0.0013 0.0019 0.0019
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.005 0.005
Brugia malayi Cytochrome P450 family protein 0.0029 0.0072 0.0072
Mycobacterium ulcerans lipase LipD 0.0043 0.0123 0.0123
Plasmodium vivax vivapain-2 0.002 0.0042 0.0042
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0017 0.0032 0.0032
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0033 0.0085 0.0085
Onchocerca volvulus 0.0033 0.0085 0.0607
Loa Loa (eye worm) hypothetical protein 0.003 0.0076 0.0076
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0123 0.0875
Entamoeba histolytica cysteine protease, putative 0.001 0.0009 0.0009

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.631 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 14.7157 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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