Detailed information for compound 1461986

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 388.416 | Formula: C17H39Cl2N3O2
  • H donors: 2 H acceptors: 2 LogP: 5.4 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCC(C(=O)N(CCCN(C)C)O)N.Cl.Cl
  • InChi: 1S/C17H37N3O2.2ClH/c1-4-5-6-7-8-9-10-11-13-16(18)17(21)20(22)15-12-14-19(2)3;;/h16,22H,4-15,18H2,1-3H3;2*1H
  • InChiKey: RFCLPMIMICSKFW-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni neuropeptide receptor 0.0019 0.0035 0.0079
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0207 0.0461
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Echinococcus multilocularis thioredoxin glutathione reductase 0.0153 0.0718 0.1621
Echinococcus multilocularis zinc finger protein 0.0023 0.0056 0.0117
Brugia malayi Heterochromatin protein 1 0.0069 0.0286 0.2157
Schistosoma mansoni opsin-like receptor 0.0019 0.0035 0.0079
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0139 0.0307
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.035 0.1717 0.2387
Trichomonas vaginalis glutathione reductase, putative 0.0053 0.0208 0.1555
Trypanosoma cruzi NADH dehydrogenase, putative 0.0014 0.0009 0.0128
Onchocerca volvulus 0.0019 0.0035 0.1299
Leishmania major hypothetical protein, conserved 0.0053 0.0206 0.2871
Echinococcus granulosus importin subunit beta 1 0.0029 0.0085 0.0185
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0139 0.0916
Trypanosoma brucei NADH dehydrogenase 0.0014 0.0009 0.0128
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0057 0.0227 0.7287
Treponema pallidum NADH oxidase 0.0053 0.0208 0.0199
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0139 0.1037
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0053 0.0208 0.0208
Trypanosoma brucei trypanothione reductase 0.0153 0.0718 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0035 0.0262
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0014 0.0009 0.0011
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0035 0.0079
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0035 0.0229
Trichomonas vaginalis MYB, putative 0.0057 0.0229 0.1713
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0014 0.0009 0.0057
Schistosoma mansoni biogenic amine receptor 0.0019 0.0035 0.0079
Schistosoma mansoni hypothetical protein 0.0074 0.0311 0.0707
Brugia malayi intermediate filament protein 0.003 0.009 0.0676
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Entamoeba histolytica hypothetical protein 0.0074 0.0311 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0057 0.0421
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0014 0.0009 0.0033
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0131 0.1831
Leishmania major hypothetical protein, conserved 0.0014 0.0009 0.0128
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0052 0.0109
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0637 0.1446
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0035 0.007
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0014 0.0009 0.0128
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0053 0.0208 0.2895
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0014 0.0009 0.0033
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Onchocerca volvulus 0.0019 0.0035 0.1299
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0022 0.0169
Schistosoma mansoni smad 0.0017 0.0024 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0207 0.0461
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0206 0.2871
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0058 0.0122
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0244 0.0545
Onchocerca volvulus 0.0019 0.0035 0.1299
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Loa Loa (eye worm) hypothetical protein 0.006 0.0244 0.1608
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0139 0.1939
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0022 0.0041
Brugia malayi ORL1-like opioid receptor 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0035 0.007
Schistosoma mansoni hypothetical protein 0.0878 0.4404 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Trichomonas vaginalis MYB3r3, putative 0.0057 0.0227 0.1703
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0035 0.0079
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0139 0.1939
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0207 0.0461
Brugia malayi Melatonin receptor type 1A 0.0019 0.0035 0.0262
Entamoeba histolytica thioredoxin reductase, putative 0.0014 0.0009 0.0243
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0131 0.1831
Echinococcus granulosus zinc finger protein 0.0023 0.0056 0.0117
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1979 1 1
Trichomonas vaginalis glutamate synthase, putative 0.0014 0.0009 0.0057
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0014 0.0009 0.0011
Brugia malayi neuropeptide F receptor 0.0019 0.0035 0.0262
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Mycobacterium ulcerans dehydrogenase 0.0014 0.0009 0.0009
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0206 0.1553
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0208 0.2895
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0035 0.0262
Echinococcus granulosus neuropeptide s receptor 0.0019 0.0035 0.007
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0035 0.007
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0014 0.0009 0.0009
Trypanosoma cruzi trypanothione reductase, putative 0.0153 0.0718 1
Schistosoma mansoni neuropeptide receptor 0.0019 0.0035 0.0079
Brugia malayi hypothetical protein 0.0074 0.0311 0.2346
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0044 0.0163 0.1074
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0014 0.0009 0.0128
Brugia malayi RNA, U transporter 1 0.0083 0.0359 0.2701
Echinococcus granulosus sex peptide receptor 0.0019 0.0035 0.007
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0014 0.0009 0.0011
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0172 0.0382
Schistosoma mansoni neuropeptide receptor 0.0019 0.0035 0.0079
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0014 0.0009 0.0057
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0035 0.007
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0014 0.0009 0.0128
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0079
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0018 0.0064
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0286 0.2147
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0035 0.007
Onchocerca volvulus 0.0019 0.0035 0.1299
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.0035 0.1299
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0024 0.0055
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0139 0.1939
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0035 0.007
Echinococcus granulosus lamin dm0 0.003 0.009 0.0194
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.0207 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0002 0.0023
Trypanosoma brucei unspecified product 0.004 0.0139 0.1939
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus chromobox protein 1 0.0069 0.0286 0.0641
Onchocerca volvulus 0.0019 0.0035 0.1299
Onchocerca volvulus 0.003 0.009 0.4076
Loa Loa (eye worm) hypothetical protein 0.0038 0.0133 0.0873
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0035 0.007
Schistosoma mansoni hypothetical protein 0.0878 0.4404 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0014 0.0009 0.0128
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0053 0.0208 0.2895
Giardia lamblia NADH oxidase lateral transfer candidate 0.0053 0.0208 0.9081
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0058 0.0121
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0217 0.1038 0.2351
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis snurportin 1 0.0311 0.1518 0.3441
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0311 0.1518 1
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0014 0.0009 0.0011
Brugia malayi Thioredoxin reductase 0.0153 0.0718 0.5405
Onchocerca volvulus 0.0019 0.0035 0.1299
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0142 0.1976
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0035 0.0229
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0139 0.1048
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0079
Echinococcus multilocularis tar DNA binding protein 0.0138 0.0637 0.1438
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0286 0.1886
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0035 0.0079
Echinococcus granulosus Smad4 0.0017 0.0024 0.0044
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.2028
Schistosoma mansoni hypothetical protein 0.0311 0.1518 0.3448
Schistosoma mansoni disulfide oxidoreductase 0.0014 0.0009 0.0021
Brugia malayi follicle stimulating hormone receptor 0.0019 0.0035 0.0262
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0558 0.2774 0.2768
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0035 0.007
Echinococcus granulosus neuropeptide receptor 0.0019 0.0035 0.007
Onchocerca volvulus 0.0019 0.0035 0.1299
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Onchocerca volvulus 0.0053 0.0207 1
Brugia malayi ImpB/MucB/SamB family protein 0.0066 0.0272 0.2051
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0208 0.0199
Trypanosoma brucei ISWI complex protein 0.0015 0.0015 0.0212
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0139 0.1939
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0022 0.0148
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0014 0.0009 0.0011
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0035 0.0079
Brugia malayi MH1 domain containing protein 0.0017 0.0024 0.0179
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0014 0.0009 0.0011
Loa Loa (eye worm) glutathione reductase 0.0153 0.0718 0.4726
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0035 0.0079
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0014 0.0009 0.0033
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0035 0.0079
Schistosoma mansoni smad1 5 8 and 0.0017 0.0024 0.0054
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0011 0.0015
Echinococcus granulosus serotonin receptor 0.0019 0.0035 0.007
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0244 0.0545
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0014 0.0009 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0035 0.0079
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0035 0.0079
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0131 0.4188
Schistosoma mansoni amine GPCR 0.0019 0.0035 0.0079
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0035 0.007
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0035 0.007
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0229 0.1713
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0035 0.007
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0046 0.0646
Schistosoma mansoni smad1 5 8 and 0.0017 0.0024 0.0054
Echinococcus multilocularis somatostatin receptor 0.0019 0.0035 0.007
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0024 0.0045
Schistosoma mansoni adenoreceptor 0.0019 0.0035 0.0079
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0057 0.0227 0.7287
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0207 0.047
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0133 0.0991
Brugia malayi mbt repeat family protein 0.0053 0.0207 0.1558
Echinococcus multilocularis Smad4 0.0017 0.0024 0.0044
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.1205 0.7935
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0035 0.007
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0172 0.0621
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0035 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Loa Loa (eye worm) hypothetical protein 0.0071 0.0297 0.1956
Trichomonas vaginalis glutaminase, putative 0.0273 0.1327 1
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0014 0.0009 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Plasmodium falciparum thioredoxin reductase 0.0053 0.0208 0.2895
Schistosoma mansoni hypothetical protein 0.0024 0.0058 0.0131
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Brugia malayi MH2 domain containing protein 0.0017 0.0024 0.0179
Entamoeba histolytica hypothetical protein 0.0024 0.0057 0.1803
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0051
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0014 0.0009 0.0128
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.0009 0.0128
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0022 0.0169
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0039 0.0136 0.1024
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0208 0.2895
Brugia malayi Bromodomain containing protein 0.0042 0.0151 0.1135
Echinococcus granulosus dna polymerase kappa 0.004 0.0139 0.0307
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0206 0.0743
Echinococcus granulosus allatostatin A receptor 0.0019 0.0035 0.007
Brugia malayi G-protein coupled receptor 0.0019 0.0035 0.0262
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0014 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Entamoeba histolytica Ran family GTPase 0.0021 0.0046 0.1445
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0131 0.1831
Echinococcus granulosus orexin receptor type 2 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0053 0.0208 0.0749
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0014 0.0009 0.0128
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0014 0.0009 0.0009
Onchocerca volvulus 0.0019 0.0035 0.1299
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0024 0.0044
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0024 0.0055
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0131 0.1831
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0046 0.0096
Echinococcus granulosus tar DNA binding protein 0.0138 0.0637 0.1438
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.012 0.0263
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.0035 0.007
Entamoeba histolytica hypothetical protein 0.0074 0.0311 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.035 0.1717 0.2387
Plasmodium vivax glutathione reductase, putative 0.0153 0.0718 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0133 0.048
Echinococcus multilocularis chromobox protein 1 0.0069 0.0286 0.0641
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0053 0.0208 0.2895
Toxoplasma gondii exonuclease III APE 0.0038 0.0131 0.0474
Loa Loa (eye worm) TAR-binding protein 0.0138 0.0637 0.4194
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0646
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0004 0.001
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0057 0.0227 0.7287
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0022 0.0041
Echinococcus granulosus g protein coupled receptor 0.0019 0.0035 0.007
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0035 0.0079
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0024 0.0045
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0148
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0121 0.0912
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.012 0.0263
Trypanosoma cruzi NADH dehydrogenase, putative 0.0014 0.0009 0.0128
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0052 0.0109
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0217 0.1038 0.2351
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0035 0.0262
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0131 0.0122
Leishmania major hypothetical protein, conserved 0.0015 0.0015 0.0212
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Echinococcus multilocularis dna polymerase kappa 0.004 0.0139 0.0307
Schistosoma mansoni importin beta-1 0.0029 0.0085 0.0194
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0389 0.1915 0.2665
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0244 0.0545
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0035 0.007
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0085 0.0185
Loa Loa (eye worm) MBCTL1 0.006 0.0244 0.1608
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0558 0.2774 0.2774
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0208 0.0199
Echinococcus multilocularis lamin dm0 0.003 0.009 0.0194
Echinococcus multilocularis smad 0.0017 0.0024 0.0044
Echinococcus granulosus hypothetical protein 0.0019 0.0035 0.007
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0014 0.0009 0.0033
Plasmodium vivax importin-beta 2, putative 0.0029 0.0085 0.1191
Onchocerca volvulus 0.0019 0.0035 0.1299
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0206 0.2871
Echinococcus granulosus GPCR family 2 0.0017 0.0022 0.0041
Brugia malayi glutamate synthase 0.0014 0.0009 0.0069
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.026 0.058
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0014 0.0009 0.0243
Brugia malayi RNA binding protein 0.0138 0.0637 0.4796
Schistosoma mansoni sulfide quinone reductase 0.0014 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0035 0.007
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0019 0.026
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1421 0.7163 1
Brugia malayi chromobox protein homolog 3 0.0038 0.0133 0.1002
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0042 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0035 0.0079
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0024 0.0055
Schistosoma mansoni biogenic amine receptor 0.0019 0.0035 0.0079
Trichomonas vaginalis glutamate synthase, putative 0.0014 0.0009 0.0057
Trypanosoma cruzi ISWI complex protein 0.0015 0.0015 0.0212
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni amine GPCR 0.0019 0.0035 0.0079
Echinococcus granulosus chromobox protein 1 0.0069 0.0286 0.0641
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0035 0.0262
Echinococcus multilocularis musashi 0.003 0.009 0.0194
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0053 0.0208 0.0278
Mycobacterium tuberculosis Probable reductase 0.035 0.1717 0.2387
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0637 0.1446
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0035 0.007
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0035 0.0079
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0151 0.0708 0.1607
Loa Loa (eye worm) hypothetical protein 0.0053 0.0207 0.1363
Schistosoma mansoni zinc finger protein 0.0023 0.0056 0.0126
Schistosoma mansoni Smad4 0.0017 0.0024 0.0054
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0133 0.6263
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0035 0.007
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0085 0.0308
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0244 0.1839
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0133 0.1855
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0011 0.0015
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0172 0.1288
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0139 0.1037
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0022 0.0041
Echinococcus granulosus intermediate filament protein 0.003 0.009 0.0194
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0148 0.1103
Schistosoma mansoni amine GPCR 0.0019 0.0035 0.0079
Brugia malayi Dopamine receptor 0.0019 0.0035 0.0262
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.006
Schistosoma mansoni biogenic amine receptor 0.0019 0.0035 0.0079
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0024 0.0055
Mycobacterium tuberculosis Probable oxidoreductase 0.0546 0.2711 0.3777
Trypanosoma cruzi ISWI complex protein 0.0015 0.0015 0.0212
Brugia malayi Dopamine receptor protein 2 0.0019 0.0035 0.0262
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0139 0.0307
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0035 0.007
Schistosoma mansoni sulfide quinone reductase 0.0014 0.0009 0.0021
Echinococcus multilocularis serotonin receptor 0.0019 0.0035 0.007
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0035 0.007
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1979 1 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0035 0.0229
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0311 0.0707
Leishmania major GTP-binding protein, putative 0.0021 0.0046 0.0646
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0206 0.1553
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0022 0.0041
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0039 0.0136 0.1024
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0014 0.0009 0.0069
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0674 0.1523
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0024 0.0045
Schistosoma mansoni glutamate synthase 0.0014 0.0009 0.0021
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0035 0.007
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Trypanosoma brucei DNA polymerase eta, putative 0.0066 0.0272 0.3794
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Brugia malayi MH2 domain containing protein 0.0249 0.1205 0.9076
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0035 0.007
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0014 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0573
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0151 0.0708 0.1599
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0207 0.1363
Loa Loa (eye worm) hypothetical protein 0.0029 0.0085 0.0563
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Schistosoma mansoni hypothetical protein 0.0015 0.0015 0.0034
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0014 0.0009 0.0128
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0009 0.0128
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0035 0.007
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0035 0.0079
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0311 0.0698
Mycobacterium ulcerans short chain dehydrogenase 0.0546 0.2711 0.2711
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0002 0.0023
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Onchocerca volvulus 0.0019 0.0035 0.1299
Onchocerca volvulus 0.0019 0.0035 0.1299
Mycobacterium tuberculosis Probable dehydrogenase 0.035 0.1717 0.2387
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Onchocerca volvulus 0.003 0.0091 0.4126
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0139 0.0139
Giardia lamblia DINP protein human, muc B family 0.004 0.0139 0.6081
Echinococcus multilocularis dna polymerase eta 0.0066 0.0272 0.0609
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0389 0.1915 0.2665
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0053 0.0208 0.2895
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0139 0.0316
Loa Loa (eye worm) acetyltransferase 0.0151 0.0708 0.466
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0035 0.007
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0035 0.007
Brugia malayi MH1 domain containing protein 0.0017 0.0024 0.0179
Schistosoma mansoni opsin-like receptor 0.0019 0.0035 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0139 0.4437
Loa Loa (eye worm) hypothetical protein 0.0053 0.0206 0.1357
Loa Loa (eye worm) Smad1 0.0017 0.0024 0.0156
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.0072
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0208 0.2895
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0014 0.0009 0.0243
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0035 0.007
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0035 0.007
Brugia malayi TAR-binding protein 0.0138 0.0637 0.4796
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0035 0.007
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0014 0.0009 0.0243
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0142 0.6198
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Onchocerca volvulus 0.0019 0.0035 0.1299
Mycobacterium tuberculosis Probable oxidoreductase 0.0389 0.1915 0.2665
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0024 0.0044
Echinococcus granulosus g protein coupled receptor 0.0019 0.0035 0.007
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0035 0.007
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0046 0.0096
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0646
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.035 0.1717 0.2387
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Leishmania major trypanothione reductase 0.0153 0.0718 1
Brugia malayi hypothetical protein 0.0034 0.0111 0.0835
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0558 0.2774 0.3865
Echinococcus granulosus dna polymerase eta 0.0066 0.0272 0.0609
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0014 0.0009 0.0128
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0148 0.1103
Giardia lamblia Myb 1-like protein 0.0057 0.0229 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0035 0.0229
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0032 0.0073
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.0035 0.0229
Brugia malayi Smad1 0.0017 0.0024 0.0179
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0035 0.0229
Trypanosoma brucei unspecified product 0.0027 0.0076 0.1066
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0229 0.1713
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0053 0.0208 0.2895
Echinococcus granulosus thioredoxin glutathione reductase 0.0153 0.0718 0.1621
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.1205 0.7935
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Brugia malayi Bromodomain containing protein 0.0079 0.0337 0.2541
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0014 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0036 0.0121 0.0797
Leishmania major hypothetical protein, conserved 0.0014 0.0009 0.0128
Loa Loa (eye worm) hypothetical protein 0.0038 0.0133 0.0876
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0053 0.0208 0.1565
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0014 0.0009 0.0243
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) glutaminase 2 0.0273 0.1327 0.8743
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0035 0.0079
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0014 0.0009 0.04
Brugia malayi RNA recognition motif domain containing protein 0.0138 0.0637 0.4796
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0558 0.2774 1
Brugia malayi Dopamine receptor protein 1 0.0019 0.0035 0.0262
Brugia malayi G protein-coupled receptor 0.0019 0.0035 0.0262
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0053 0.0208 0.0208
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0057 0.0421
Toxoplasma gondii thioredoxin reductase 0.0153 0.0718 0.2586
Trichomonas vaginalis mercuric reductase, putative 0.0053 0.0208 0.1555
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0046 0.0167
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0035 0.0262
Echinococcus granulosus snurportin 1 0.0311 0.1518 0.3441
Brugia malayi acetyltransferase, GNAT family protein 0.0151 0.0708 0.533
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0206 0.2871
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0306
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0035 0.007
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0035 0.0262
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0053 0.0208 0.0199
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0035 0.0262
Loa Loa (eye worm) RNA binding protein 0.0138 0.0637 0.4194
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0057 0.0421
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0014 0.0009 0.0011
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0053 0.0208 0.2895
Trypanosoma brucei unspecified product 0.0027 0.0076 0.1066
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1421 0.7163 1
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0139 0.0139
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0035 0.0079
Echinococcus granulosus bloom syndrome protein 0.0024 0.0058 0.0121
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0244 0.0545
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0131 0.0289
Schistosoma mansoni ap endonuclease 0.0038 0.0131 0.0298
Trichomonas vaginalis pc-MYB2, putative 0.0057 0.0227 0.1703
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Schistosoma mansoni hypothetical protein 0.0036 0.0121 0.0275
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0172 0.0621
Leishmania major DNA polymerase eta, putative 0.0066 0.0272 0.3794
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0014 0.0009 0.0057
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0002 0.0023
Leishmania major DNA polymerase kappa, putative 0.004 0.0139 0.1939
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0207 0.047
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0139 0.0182
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0311 0.0698
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0035 0.007
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0043 0.0599
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0148 0.7014
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0035 0.007
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0035 0.007
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0014 0.0009 0.0009
Trypanosoma cruzi DNA polymerase eta, putative 0.0066 0.0272 0.3794
Echinococcus granulosus geminin 0.0878 0.4404 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.0035 0.1299
Echinococcus granulosus neuropeptide receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0053 0.0206 0.1357
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0035 0.007
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0035 0.007
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0035 0.007
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0206 0.2871
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0591
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0646
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0207 0.047
Giardia lamblia Thioredoxin reductase 0.0014 0.0009 0.04
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0004 0.0028
Trichomonas vaginalis ran, putative 0.0021 0.0046 0.0338
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0142 0.4523
Loa Loa (eye worm) glutaminase 0.0273 0.1327 0.8743
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0024 0.0156
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.009 0.0591
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0053 0.0208 0.0463
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Schistosoma mansoni bromodomain containing protein 0.0067 0.0278 0.0631
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0035 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0009 0.0128
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0139 0.1939
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0637 0.1446
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.026 0.058
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0131 0.0171
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.009 0.0676
Plasmodium falciparum glutathione reductase 0.0053 0.0208 0.2895
Brugia malayi mbt repeat family protein 0.0053 0.0207 0.1558
Brugia malayi putative neuropeptide receptor 0.0019 0.0035 0.0262
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0014 0.0009 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0133 0.0991
Trichomonas vaginalis MYB72, putative 0.0057 0.0227 0.1703
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0053 0.0208 0.0208
Brugia malayi MH2 domain containing protein 0.0017 0.0024 0.0179
Brugia malayi hypothetical protein 0.0053 0.0206 0.1552
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0035 0.0229
Brugia malayi larval opioid receptor 0.0019 0.0035 0.0262
Echinococcus multilocularis sex peptide receptor 0.0019 0.0035 0.007
Brugia malayi AKH receptor 0.0019 0.0035 0.0262
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0058 0.0122
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0119 0.0543 0.3573
Brugia malayi PHD-finger family protein 0.0029 0.0083 0.0623
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0637 0.1446
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0076 0.056
Trichomonas vaginalis C-MYB, putative 0.0057 0.0227 0.1703
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0024 0.0156
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0014 0.0009 0.0069
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0131 0.099
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0076 0.1066
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0053 0.0208 0.0463
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0051
Brugia malayi RE15519p 0.0019 0.0035 0.0262
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0052 0.0118
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0131 0.0289
Schistosoma mansoni chromobox protein 0.0069 0.0286 0.065
Echinococcus multilocularis serotonin receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni zinc finger protein 0.0015 0.0015 0.0034
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0057 0.0801
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0207 0.0461
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0014 0.0009 0.0128
Onchocerca volvulus 0.0019 0.0035 0.1299
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0035 0.007
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0172 0.1288
Echinococcus granulosus smad 0.0017 0.0024 0.0044
Loa Loa (eye worm) thioredoxin reductase 0.0153 0.0718 0.4726
Echinococcus granulosus glutamate synthase 0.0014 0.0009 0.0011
Loa Loa (eye worm) intermediate filament protein 0.003 0.009 0.0591
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.0009 0.0128
Loa Loa (eye worm) programmed cell death 8 0.0014 0.0009 0.006
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0035 0.007
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0035 0.007
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0014 0.0009 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni ran 0.0021 0.0046 0.0105
Schistosoma mansoni smad1 5 8 and 0.0017 0.0024 0.0054
Giardia lamblia Glutamate synthase 0.0014 0.0009 0.04
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Brugia malayi Serotonin receptor 0.0019 0.0035 0.0262
Echinococcus granulosus fmrfamide receptor 0.0019 0.0035 0.007
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0053 0.0208 0.0472
Toxoplasma gondii NADPH-glutathione reductase 0.0053 0.0208 0.0749
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0085 0.1191
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0139 0.1939
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0131 0.0131
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0024 0.0054
Schistosoma mansoni histamine h1 receptor 0.0019 0.0035 0.0079
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0024 0.0045
Mycobacterium ulcerans glutaminase 0.0273 0.1327 0.1327
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.0009 0.0128
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0076 0.1066
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0051
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0014 0.0009 0.0009
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0046 0.0302
Onchocerca volvulus 0.0019 0.0035 0.1299
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0014 0.0009 0.0243
Brugia malayi neuropeptide F receptor 0.0019 0.0035 0.0262
Schistosoma mansoni opsin-like receptor 0.0019 0.0035 0.0079
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0035 0.0229
Mycobacterium ulcerans glutamate synthase subunit beta 0.0014 0.0009 0.0009
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0131 0.0979
Brugia malayi sulfakinin receptor protein 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0035 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Plasmodium falciparum importin beta, putative 0.0029 0.0085 0.1191
Loa Loa (eye worm) hypothetical protein 0.003 0.0091 0.0598
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0172 0.2403
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0035 0.007
Brugia malayi glutathione reductase 0.0153 0.0718 0.5405
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0035 0.007
Schistosoma mansoni tar DNA-binding protein 0.0138 0.0637 0.1446
Schistosoma mansoni hypothetical protein 0.0014 0.0009 0.0021
Mycobacterium ulcerans monoxygenase 0.0014 0.0009 0.0009
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0035 0.007
Schistosoma mansoni neuropeptide receptor 0.0019 0.0035 0.0079
Echinococcus multilocularis GPCR, family 2 0.0017 0.0022 0.0041
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) RecQ helicase 0.0024 0.0058 0.0379
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Plasmodium vivax ferrodoxin reductase, putative 0.0014 0.0009 0.0128
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0035 0.0079
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0053 0.0208 0.2895
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0057 0.0227 0.7287
Leishmania major importin beta-1 subunit, putative 0.0024 0.0057 0.0801
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Loa Loa (eye worm) hypothetical protein 0.0017 0.0024 0.0159
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0014 0.0009 0.0128
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0046 0.0349
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0014 0.0009 0.0033
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Leishmania major DNA polymerase eta, putative 0.0038 0.0133 0.1855
Echinococcus multilocularis chromobox protein 1 0.0069 0.0286 0.0641
Entamoeba histolytica disulphide oxidoreductase, putative 0.0014 0.0009 0.0243
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0139 0.1939
Toxoplasma gondii selenide, water dikinase 0.0014 0.0009 0.0033
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0131 0.1831
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni hypothetical protein 0.0021 0.0042 0.0096
Schistosoma mansoni lamin 0.003 0.009 0.0204
Trichomonas vaginalis C-MYB, putative 0.0057 0.0227 0.1703
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0035 0.007
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0035 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0076 0.056
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.035 0.1717 0.2387
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0058 0.0422
Schistosoma mansoni hypothetical protein 0.033 0.1615 0.3667
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0035 0.0079
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0208 0.2895
Schistosoma mansoni myosin xvIII 0.0019 0.0035 0.0079
Echinococcus granulosus lamin 0.003 0.009 0.0194
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0058 0.0434
Echinococcus granulosus g protein coupled receptor 0.0019 0.0035 0.007
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0138 0.0637 0.4194
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.035 0.1717 0.2387
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0035 0.007
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0389 0.1915 0.2665
Entamoeba histolytica hypothetical protein 0.0074 0.0311 1
Onchocerca volvulus 0.0019 0.0035 0.1299
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0054
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0035 0.007
Schistosoma mansoni intermediate filament proteins 0.003 0.009 0.0204
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0035 0.0262
Schistosoma mansoni amine GPCR 0.0019 0.0035 0.0079
Onchocerca volvulus 0.0019 0.0035 0.1299
Brugia malayi Importin beta-1 subunit 0.0029 0.0085 0.0644
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0024 0.0044
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0206 0.2871
Trichomonas vaginalis pc-MYB2, putative 0.0057 0.0227 0.1703
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0014 0.0009 0.0128
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0139 0.0182
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0058 0.0422
Echinococcus multilocularis geminin 0.0878 0.4404 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0053 0.0208 0.2895
Brugia malayi Serotonin receptor 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0054
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0057 0.0227 0.1703
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0131 0.0865
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0131 0.0979
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0019 0.0125
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0131 0.5744
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0046 0.0646
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0206 0.1357
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0035 0.007
Brugia malayi GnHR receptor homolog 0.0019 0.0035 0.0262
Trichomonas vaginalis apoptosis inducing factor, putative 0.0014 0.0009 0.0057
Leishmania major NADH dehydrogenase, putative 0.0014 0.0009 0.0128
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0208 0.2895
Mycobacterium ulcerans ferredoxin reductase 0.0014 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0153 0.0718 0.099
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0139 0.0316
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0014 0.0009 0.006
Brugia malayi CHD4 protein 0.0013 0.0004 0.0032
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0035 0.0079
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0035 0.0079
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0057 0.0229 0.0825
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0014 0.0009 0.0009
Plasmodium vivax thioredoxin reductase, putative 0.0153 0.0718 1
Onchocerca volvulus 0.0019 0.0035 0.1299
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0014 0.0009 0.0057
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0139 0.1939
Schistosoma mansoni amine GPCR 0.0019 0.0035 0.0079
Echinococcus multilocularis glutamate synthase 0.0014 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.1979 1 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0035 0.007
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0019 0.0143
Schistosoma mansoni lamin 0.003 0.009 0.0204
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0035 0.007
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0035 0.007
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Loa Loa (eye worm) hypothetical protein 0.0066 0.0272 0.1793
Schistosoma mansoni glutaminase 0.0273 0.1327 0.3014
Echinococcus multilocularis lamin 0.003 0.009 0.0194
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0131 0.1831
Leishmania major hypothetical protein, conserved 0.0014 0.0009 0.0128
Schistosoma mansoni hypothetical protein 0.0017 0.0022 0.0051
Plasmodium falciparum ferrodoxin reductase-like protein 0.0014 0.0009 0.0128
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0035 0.007
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0131 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0139 0.1939
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0085 0.1191
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni glutamate synthase 0.0014 0.0009 0.0021
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0206 0.2871
Loa Loa (eye worm) hypothetical protein 0.0019 0.0035 0.0229
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0244 0.0554
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0009 0.0128
Brugia malayi glutaminase DH11.1 0.0273 0.1327 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0173 0.1138
Brugia malayi hypothetical protein 0.0019 0.0035 0.0262
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0035 0.007
Schistosoma mansoni ap endonuclease 0.0038 0.0131 0.0298
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0076 0.1066
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0035 0.007
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0079
Mycobacterium ulcerans hypothetical protein 0.0014 0.0009 0.0009
Plasmodium falciparum glutathione reductase 0.0153 0.0718 1
Entamoeba histolytica hypothetical protein 0.0074 0.0311 1
Schistosoma mansoni ran 0.0021 0.0046 0.0105
Brugia malayi G-protein coupled receptor 0.0019 0.0035 0.0262
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0035 0.0079
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0035 0.0229
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0024 0.0044
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0057 0.0227 0.7287
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0035 0.0229
Onchocerca volvulus 0.003 0.009 0.4076
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0035 0.007
Mycobacterium ulcerans NADH dehydrogenase 0.0014 0.0009 0.0009
Schistosoma mansoni glutamate synthase 0.0014 0.0009 0.0021
Schistosoma mansoni hypothetical protein 0.0019 0.0035 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0035 0.007
Schistosoma mansoni DNA polymerase eta 0.0066 0.0272 0.0618
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0014 0.0009 0.0128
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0208 0.2895
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0286 0.2147
Echinococcus granulosus somatostatin receptor 0.0019 0.0035 0.007
Plasmodium falciparum thioredoxin reductase 0.0153 0.0718 1
Schistosoma mansoni chromobox protein 0.0069 0.0286 0.065

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 100 uM Inhibition of Bacillus cereus phosphatidylcholine preferred phospholipase C after 100 seconds ChEMBL. 21071231
LD50 (ADMET) = 40 uM Cytotoxicity against human A549 cells after 24 hrs by MTT assay ChEMBL. 21071231

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.