Detailed information for compound 1462000

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 308.735 | Formula: C15H14ClFN2O2
  • H donors: 1 H acceptors: 1 LogP: 3.18 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1cccc(c1Oc1ncccc1OC1CCNC1)Cl
  • InChi: 1S/C15H14ClFN2O2/c16-11-3-1-4-12(17)14(11)21-15-13(5-2-7-19-15)20-10-6-8-18-9-10/h1-5,7,10,18H,6,8-9H2
  • InChiKey: NYOUEYCHUPCVGU-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 3 Starlite/ChEMBL References
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 4 Starlite/ChEMBL References
Homo sapiens solute carrier family 6 (neurotransmitter transporter), member 2 Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) solute carrier family 6 member 4 Get druggable targets OG5_128364 All targets in OG5_128364
Treponema pallidum sodium- and chloride- dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Onchocerca volvulus Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum expressed protein Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent noradrenaline transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus multilocularis serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Brugia malayi Sodium:neurotransmitter symporter family protein Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) serotonin transporter b Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus serotonin transporter Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum IPR000175,Sodium:neurotransmitter symporter,domain-containing Get druggable targets OG5_128364 All targets in OG5_128364
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma mansoni norepinephrine/norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum ko:K05336 solute carrier family 6 (neurotransmitter transporter), invertebrate, putative Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum Sodium-dependent dopamine transporter, putative Get druggable targets OG5_128364 All targets in OG5_128364
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum Octopamine receptor, putative Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma mansoni sodium/chloride dependent transporter Get druggable targets OG5_128364 All targets in OG5_128364
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) norepinephrine transporter Get druggable targets OG5_128364 All targets in OG5_128364

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 2 617 aa 638 aa 32.5 %
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 3 620 aa 579 aa 33.2 %
Brugia malayi Sodium:neurotransmitter symporter family protein solute carrier family 6 (neurotransmitter transporter), member 4 630 aa 574 aa 31.5 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.054 0.0784
Brugia malayi hypothetical protein 0.0026 0.0063 0.0422
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.0122 0.1024
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0007 0.0044
Leishmania major hypothetical protein, conserved 0.0026 0.0063 0.0607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0059
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0106 0.149
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0082 0.0678
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0191 0.0536
Onchocerca volvulus Putative cubilin 0.0017 0.0015 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0185 0.0266
Schistosoma mansoni septate junction protein 0.0017 0.0015 0.0042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1181
Trypanosoma cruzi cysteine peptidase, putative 0.0057 0.0222 0.032
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0191 0.0274
Plasmodium vivax vivapain-1 0.0041 0.0137 0.1327
Loa Loa (eye worm) hypothetical protein 0.0098 0.0439 0.2773
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0144 0.0681 0.6837
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0084 0.0235
Loa Loa (eye worm) Smad1 0.0017 0.0011 0.0071
Brugia malayi MH1 domain containing protein 0.0017 0.0011 0.0066
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0117 0.0541 0.1519
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0021 0.0156
Entamoeba histolytica hypothetical protein 0.0112 0.0511 0.7479
Brugia malayi Cathepsin L-like precursor 0.0057 0.0222 0.1513
Loa Loa (eye worm) E1-E2 ATPase 0.0085 0.0372 0.2347
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.1161 0.3261
Echinococcus granulosus protein jagged 1 0.0017 0.0015 0.0042
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0006 0.0023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0084 0.0235
Trichomonas vaginalis chromobox protein, putative 0.0154 0.0732 0.6269
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0359 0.1008
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0191 0.0536
Trypanosoma brucei P-type H+-ATPase, putative 0.0085 0.0372 0.433
Brugia malayi hypothetical protein 0.0121 0.0561 0.3843
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0144 0.0681 1
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0277 0.1889
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0144 0.0681 0.5829
Echinococcus granulosus phospholipid transporting ATPase IF 0.0016 0.0006 0.0016
Echinococcus multilocularis phospholipid transporting ATPase IF 0.0016 0.0006 0.0016
Echinococcus granulosus microtubule associated protein 2 0.0688 0.3534 0.9925
Entamoeba histolytica hypothetical protein 0.0035 0.0106 0.149
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0087 0.0315
Echinococcus multilocularis chromobox protein 2 0.0035 0.0106 0.0299
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0191 0.0274
Echinococcus granulosus thioredoxin glutathione reductase 0.0144 0.0678 0.1905
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0021 0.0229
Onchocerca volvulus 0.0017 0.0015 0.0063
Trichomonas vaginalis set domain proteins, putative 0.0237 0.1167 1
Echinococcus granulosus tumor protein p63 0.0337 0.1692 0.4751
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0222 0.1881
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0018 0.0021 0.0156
Loa Loa (eye worm) blistered cuticle protein 3 0.0053 0.0205 0.1294
Treponema pallidum hypothetical protein 0.0027 0.0065 0.0018
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0447 0.1256
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0162 0.0776 0.4903
Loa Loa (eye worm) hypothetical protein 0.0074 0.0315 0.199
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0042 0.0146 0.014
Trichomonas vaginalis pc-MYB2, putative 0.0105 0.0477 0.4073
Trypanosoma brucei P-type H+-ATPase, putative 0.0085 0.0372 0.433
Echinococcus multilocularis neurogenic locus protein delta 0.0017 0.0015 0.0042
Entamoeba histolytica hypothetical protein 0.0023 0.0046 0.0604
Trypanosoma cruzi cruzipain precursor, putative 0.015 0.0714 0.1039
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0006 0.0023
Plasmodium falciparum thioredoxin reductase 0.0144 0.0678 0.6797
Echinococcus granulosus intermediate filament protein 0.0027 0.0065 0.0183
Schistosoma mansoni laminin gamma-3 chain 0.0017 0.0015 0.0042
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0006 0.0023
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0277 0.1747
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0159 0.1835
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0011 0.0032
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0145 0.0408
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.005 0.0185 0.2142
Schistosoma mansoni cathepsin C 0.0018 0.0021 0.0059
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0106 0.149
Brugia malayi hypothetical protein 0.0122 0.0565 0.3871
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0328 0.1644 0.2246
Plasmodium vivax thioredoxin reductase, putative 0.0144 0.0678 0.6797
Echinococcus granulosus chromobox protein 1 0.0154 0.0732 0.2057
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0106 0.0888
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0021 0.0133
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0191 0.1892
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0018 0.0021 0.0156
Loa Loa (eye worm) hypothetical protein 0.0055 0.0211 0.1333
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0021 0.0133
Echinococcus multilocularis serotonin receptor 0.0159 0.0757 0.2125
Mycobacterium ulcerans DNA polymerase IV 0.0117 0.054 0.0533
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0068 0.0281 0.2393
Loa Loa (eye worm) cathepsin B 0.0018 0.0021 0.0133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0041 0.0137 0.1573
Toxoplasma gondii thioredoxin reductase 0.0144 0.0678 0.2453
Leishmania major DNA polymerase kappa, putative 0.0097 0.0435 0.4355
Brugia malayi Thioredoxin reductase 0.0144 0.0678 0.4648
Loa Loa (eye worm) hypothetical protein 0.0016 0.0006 0.0036
Echinococcus granulosus smad 0.0017 0.0011 0.0032
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.1161 0.3261
Giardia lamblia Cathepsin L precursor 0.0018 0.0021 0.0229
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.005 0.0185 0.014
Schistosoma mansoni hypothetical protein 0.0052 0.0195 0.0547
Brugia malayi Papain family cysteine protease containing protein 0.0041 0.0137 0.0929
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0184 0.0518
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0115 0.0323
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0106 0.0888
Echinococcus granulosus neuropeptide s receptor 0.047 0.2391 0.6716
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0191 0.1613
Trypanosoma brucei DNA polymerase eta, putative 0.0141 0.0665 0.7774
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.005 0.0185 0.1262
Brugia malayi Valyl-tRNA synthetase 0.0035 0.0106 0.0719
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0159 0.0447
Onchocerca volvulus 0.0053 0.0205 0.1372
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0144 0.0681 1
Mycobacterium ulcerans DNA polymerase IV 0.0117 0.054 0.0533
Echinococcus granulosus cathepsin l cysteine peptidase 0.0057 0.0222 0.0623
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0184 0.0518
Brugia malayi hypothetical protein 0.002 0.0027 0.0175
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0027 0.0218
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0021 0.0156
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0097 0.0435 0.2961
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0059
Echinococcus granulosus neurogenic locus notch protein 0.0017 0.0015 0.0042
Giardia lamblia Cathepsin L-like protease 0.0018 0.0021 0.0229
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0007 0.0006
Brugia malayi hypothetical protein 0.005 0.0184 0.1255
Echinococcus multilocularis peroxidasin 0.0053 0.0205 0.0575
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0007 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0106 0.0886
Schistosoma mansoni lipoxygenase 0.0055 0.0213 0.0598
Echinococcus multilocularis microtubule associated protein 2 0.0688 0.3534 0.9925
Loa Loa (eye worm) hypothetical protein 0.0122 0.0565 0.3568
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0252
Trichomonas vaginalis MYB72, putative 0.0105 0.0477 0.4073
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.0439 0.3006
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0923
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0714 0.1039
Loa Loa (eye worm) RNA binding protein 0.0067 0.0277 0.1747
Schistosoma mansoni smad1 5 8 and 0.0017 0.0011 0.0032
Brugia malayi Cathepsin L-like cysteine proteinase 0.0035 0.0106 0.0717
Onchocerca volvulus 0.0134 0.0628 0.4285
Schistosoma mansoni DNA helicase recq5 0.0019 0.0025 0.007
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0035 0.0106 0.0299
Echinococcus granulosus Ankyrin repeat domain containing protein 0.009 0.0394 0.1107
Brugia malayi Cytochrome P450 family protein 0.0016 0.0007 0.0036
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0204 0.0995 1
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0064 0.0261 0.0378
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0191 0.1613
Echinococcus granulosus protein jagged 2 0.0017 0.0015 0.0042
Mycobacterium tuberculosis Probable dehydrogenase 0.0328 0.1644 0.2246
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0113 0.0318
Onchocerca volvulus 0.0292 0.1457 1
Onchocerca volvulus 0.0017 0.0015 0.0063
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0097 0.0435 0.0546
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0075
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0016 0.0006 0.0023
Echinococcus granulosus cathepsin L cysteine proteinase 0.0057 0.0222 0.0623
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0012 0.0033
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.00000069766 0.0000019594
Plasmodium falciparum thioredoxin reductase 0.005 0.0185 0.1817
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Loa Loa (eye worm) hypothetical protein 0.0292 0.1457 0.9199
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0063 0.0088
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0113 0.0948
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0041 0.0137 0.1573
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0106 0.1017
Schistosoma mansoni cation-transporting atpase fly 0.0016 0.0006 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0156
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0107 0.0487 0.5684
Loa Loa (eye worm) norepinephrine transporter 0.0292 0.1457 0.9199
Schistosoma mansoni type V p-type atpase isoform 0.0016 0.0006 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0145 0.1222
Plasmodium vivax unspecified product 0.0022 0.004 0.0347
Echinococcus multilocularis neural cadherin 0.0017 0.0015 0.0042
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0106 0.048 0.4096
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0042 0.0146 0.0209
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0102 0.046 0.1292
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0105 0.0477 0.4073
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Brugia malayi EGF-like domain containing protein 0.0017 0.0015 0.009
Echinococcus multilocularis smad 0.0017 0.0011 0.0032
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0042 0.0146 0.0139
Echinococcus multilocularis cathepsin L cysteine protease 0.0057 0.0222 0.0623
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0144 0.0681 1
Echinococcus multilocularis sodium and chloride dependent glycine 0.005 0.0184 0.0518
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0394 0.1107
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0211 0.2444
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0185 0.0266
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0027 0.0065 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Echinococcus granulosus cathepsin b 0.0018 0.0021 0.0059
Loa Loa (eye worm) hypothetical protein 0.0144 0.068 0.4291
Trypanosoma cruzi cysteine peptidase, putative 0.1319 0.6849 1
Trypanosoma cruzi P-type H+-ATPase, putative 0.0085 0.0372 0.0539
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0117 0.0541 0.4622
Schistosoma mansoni patched 1 0.0042 0.0145 0.0408
Loa Loa (eye worm) glutathione reductase 0.0144 0.0678 0.4282
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.005 0.0185 0.1817
Brugia malayi polk-prov protein 0.0055 0.0211 0.1439
Brugia malayi EGF-like domain containing protein 0.0017 0.0015 0.009
Brugia malayi Cadherin domain containing protein 0.0017 0.0015 0.009
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0012 0.0033
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0184 0.1255
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.005 0.0184 0.0518
Brugia malayi hypothetical protein 0.0236 0.1161 0.7968
Toxoplasma gondii cathepsin B 0.0018 0.0021 0.0076
Plasmodium vivax cation transporting ATPase, putative 0.0042 0.0146 0.142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Echinococcus granulosus chromobox protein 1 0.0154 0.0732 0.2057
Brugia malayi MH1 domain containing protein 0.0017 0.0011 0.0066
Schistosoma mansoni cation-transporting ATPase 0.0042 0.0146 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0063 0.0518
Echinococcus granulosus phospholipid transporting ATPase VA 0.0027 0.0065 0.0181
Plasmodium falciparum calcium-transporting ATPase 0.0177 0.0855 0.858
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0042
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0184 0.1255
Giardia lamblia GTOR 0.0045 0.0159 0.2273
Leishmania major cation-transporting ATPase, putative 0.0016 0.0006 0.0027
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0202 0.1273
Echinococcus multilocularis cathepsin b 0.0018 0.0021 0.0059
Loa Loa (eye worm) hypothetical protein 0.0292 0.1457 0.9199
Schistosoma mansoni hypothetical protein 0.0041 0.0137 0.0385
Echinococcus granulosus protein jagged 2 0.0017 0.0015 0.0042
Onchocerca volvulus 0.0017 0.0015 0.0063
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0027 0.0065 0.0234
Toxoplasma gondii hypothetical protein 0.005 0.0184 0.0667
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0111 0.1272
Trypanosoma brucei DNA polymerase kappa, putative 0.0097 0.0435 0.5074
Leishmania major cathepsin L-like protease 0.0057 0.0222 0.2207
Echinococcus multilocularis phosphoserine phosphatase 0.0027 0.0065 0.0181
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0025 0.009
Giardia lamblia Cathepsin L precursor 0.0018 0.0021 0.0229
Schistosoma mansoni copper ABC transporter ATPase 0.0042 0.0146 0.041
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0134 0.0629 0.4311
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Chlamydia trachomatis metal transport ATPase 0.0042 0.0146 0.01
Brugia malayi GCC2 and GCC3 family protein 0.0017 0.0015 0.009
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0063 0.0581
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.005 0.0185 0.0179
Echinococcus granulosus cathepsin b 0.0018 0.0021 0.0059
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0057 0.0222 0.1401
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.005 0.0185 0.0521
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0106 0.048 0.4096
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0191 0.2204
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0021 0.0059
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0018 0.0021 0.0156
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0105 0.0477 0.4073
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0328 0.1644 0.2246
Loa Loa (eye worm) hypothetical protein 0.0159 0.0757 0.4778
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0072 0.0101
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.192 1 1
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0042 0.0146 0.1681
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0222 0.1881
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0065 0.053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0025 0.007
Echinococcus multilocularis bloom syndrome protein 0.0046 0.0168 0.0472
Giardia lamblia Copper-transporting P-type ATPase 0.0042 0.0146 0.2079
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0113 0.0948
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0042 0.0146 0.0139
Loa Loa (eye worm) hypothetical protein 0.0113 0.0517 0.3266
Schistosoma mansoni intermediate filament proteins 0.0027 0.0065 0.0183
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0222 0.1881
Schistosoma mansoni notch 0.0017 0.0015 0.0042
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0159 0.0447
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0105 0.0477 0.6976
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.054 0.0784
Brugia malayi Potential phospholipid-transporting ATPase IA 0.0016 0.0006 0.0027
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0028 0.0072 0.0261
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.0137 0.1151
Echinococcus granulosus GPCR family 2 0.0017 0.0012 0.0033
Schistosoma mansoni smad1 5 8 and 0.0017 0.0011 0.0032
Entamoeba histolytica cysteine proteinase, putative 0.0041 0.0137 0.1943
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0025 0.007
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0017 0.0015 0.009
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0055 0.0723
Trichomonas vaginalis cation-transporting ATPase, putative 0.0042 0.0146 0.123
Onchocerca volvulus 0.005 0.0184 0.1231
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0007 0.0044
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0042 0.0146 0.123
Loa Loa (eye worm) hypothetical protein 0.0057 0.0222 0.1401
Mycobacterium ulcerans flavoprotein disulfide reductase 0.005 0.0185 0.0179
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0057 0.0222 0.1881
Schistosoma mansoni type V p-type atpase isoform 0.0042 0.0146 0.041
Echinococcus multilocularis dna polymerase eta 0.0141 0.0665 0.1868
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.005 0.0185 0.2142
Loa Loa (eye worm) hypothetical protein 0.002 0.0027 0.0172
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0021 0.0156
Brugia malayi Cathepsin L-like precursor 0.0057 0.0222 0.1513
Plasmodium vivax hypothetical protein, conserved 0.005 0.0184 0.1806
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0042 0.0146 0.2079
Giardia lamblia Cathepsin L precursor 0.0018 0.0021 0.0229
Brugia malayi Animal haem peroxidase family protein 0.0053 0.0205 0.1396
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0042 0.0146 0.2079
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0035 0.0107 0.0385
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0359 0.1008
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0012 0.0033
Echinococcus multilocularis neurogenic locus protein delta 0.0017 0.0015 0.0042
Toxoplasma gondii cathepsin CPL 0.0057 0.0222 0.0803
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0042 0.0146 0.0992
Echinococcus granulosus cathepsin L 0.0018 0.0021 0.0059
Brugia malayi chromobox protein homolog 3 0.0091 0.0403 0.2761
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0041 0.0137 0.0385
Loa Loa (eye worm) hypothetical protein 0.002 0.0027 0.0172
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.054 0.6302
Onchocerca volvulus Peroxidase homolog 0.0053 0.0205 0.1372
Loa Loa (eye worm) fibroinase 0.0057 0.0222 0.1401
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0097 0.0435 0.4355
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0102 0.046 0.1292
Plasmodium vivax vivapain-2 0.0057 0.0222 0.2185
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0021 0.0156
Echinococcus multilocularis cation transporting ATPase 13A1 0.0042 0.0146 0.041
Brugia malayi phospholipid-translocating P-type ATPase, flippase family protein 0.0016 0.0006 0.0027
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0364 0.1836 0.2516
Trypanosoma cruzi P-type H+-ATPase, putative 0.0085 0.0372 0.0539
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0086 0.0374 0.5454
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0011 0.0032
Schistosoma mansoni hypothetical protein 0.0035 0.0106 0.0299
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0055 0.0443
Echinococcus granulosus neurogenic locus notch protein 4 0.0017 0.0015 0.0042
Echinococcus multilocularis copper transporting ATPase 1 0.0042 0.0146 0.041
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0055 0.0075
Entamoeba histolytica hypothetical protein 0.0112 0.0511 0.7479
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0133
Echinococcus multilocularis fibropellin Ia 0.0017 0.0015 0.0042
Onchocerca volvulus 0.0017 0.0015 0.0063
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0177 0.0855 0.24
Brugia malayi EGF-like domain containing protein 0.0017 0.0015 0.009
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.066 0.1854
Echinococcus multilocularis lamin 0.0027 0.0065 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Echinococcus multilocularis cysteine protease 0.0057 0.0222 0.0623
Loa Loa (eye worm) ctsf protein 0.0057 0.0222 0.1401
Brugia malayi Melibiase family protein 0.0068 0.0281 0.1922
Echinococcus multilocularis cysteine protease 0.0057 0.0222 0.0623
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0025 0.007
Leishmania major DNA polymerase eta, putative 0.0079 0.0336 0.3361
Trypanosoma brucei unspecified product 0.0063 0.0253 0.2932
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0025 0.0284
Brugia malayi Cathepsin L-like precursor 0.0035 0.0106 0.0717
Trypanosoma brucei DNA polymerase IV, putative 0.0117 0.054 0.6302
Loa Loa (eye worm) solute carrier family 6 member 4 0.0292 0.1457 0.9199
Onchocerca volvulus Dual oxidase homolog 0.0053 0.0205 0.1372
Brugia malayi CHD4 protein 0.0036 0.0115 0.0777
Onchocerca volvulus Chorion peroxidase homolog 0.0053 0.0205 0.1372
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0112 0.0511 0.1435
Onchocerca volvulus 0.005 0.0184 0.1231
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0021 0.0133
Brugia malayi Pre-SET motif family protein 0.0208 0.1016 0.6971
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0099 0.0825
Leishmania major DNA polymerase kappa, putative 0.0028 0.0072 0.0696
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0213 0.0598
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.054 0.6302
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.005 0.0185 0.0266
Loa Loa (eye worm) hypothetical protein 0.0036 0.0114 0.0718
Loa Loa (eye worm) MH2 domain-containing protein 0.0244 0.1203 0.7598
Echinococcus granulosus cathepsin L 0.0041 0.0137 0.0385
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0025 0.007
Echinococcus multilocularis tumor protein p63 0.0337 0.1692 0.4751
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0089 0.0843
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0776 0.2181
Leishmania major dihydrolipoamide dehydrogenase, putative 0.005 0.0185 0.1839
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0063 0.0581
Echinococcus multilocularis dna polymerase kappa 0.0117 0.054 0.1516
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0025 0.0194
Trypanosoma brucei phospholipid-translocating ATPase, putative 0.0016 0.0006 0.0032
Echinococcus granulosus Chromo domain 0.0035 0.0106 0.0299
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0106 0.0886
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0021 0.0156
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0075 0.0209
Brugia malayi M-phase phosphoprotein, mpp8 0.0124 0.0576 0.395
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0249 0.0698
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0364 0.1836 0.2516
Toxoplasma gondii Copper-exporting ATPase 0.0016 0.0006 0.0021
Trichomonas vaginalis C-MYB, putative 0.0105 0.0477 0.4073
Onchocerca volvulus 0.0094 0.0417 0.2835
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0099 0.0825
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.004 0.0252
Echinococcus multilocularis lysosomal alpha glucosidase 0.0162 0.0776 0.2181
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0222 0.1881
Schistosoma mansoni hypothetical protein 0.0693 0.3561 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0184 0.0518
Leishmania major copper-transporting ATPase-like protein, putative 0.0042 0.0146 0.1443
Echinococcus granulosus lysosomal alpha glucosidase 0.0162 0.0776 0.2181
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0191 0.1613
Trichomonas vaginalis glutathione reductase, putative 0.005 0.0185 0.1568
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0184 0.0518
Trypanosoma brucei DNA polymerase IV, putative 0.0117 0.054 0.6302
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Echinococcus multilocularis Chromobox protein 3 0.0035 0.0106 0.0299
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0202 0.1373
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0213 0.0598
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.005 0.0185 0.1817
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0107 0.0487 0.0707
Leishmania major dihydrolipoamide dehydrogenase, putative 0.005 0.0185 0.1839
Onchocerca volvulus 0.0049 0.0183 0.1221
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0042
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0671
Brugia malayi TAR-binding protein 0.0067 0.0277 0.1889
Leishmania major aminophospholipid translocase, putative 0.0016 0.0006 0.0027
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0021 0.0027
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0021 0.0133
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0113 0.0318
Schistosoma mansoni phospholipid-transporting atpase 0.0016 0.0006 0.0016
Giardia lamblia Myb 1-like protein 0.0106 0.0479 0.7014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0021 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0185 0.0266
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.0139 0.1343
Echinococcus multilocularis chromobox protein 1 0.0154 0.0732 0.2057
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0144 0.0681 0.7964
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.1164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0185 0.0266
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.005 0.0185 0.2142
Echinococcus multilocularis fat cadherin tumor suppressor 0.0017 0.0015 0.0042
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0159 0.1006
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0106 0.0298
Leishmania major phospholipid-translocating P-type ATPase (flippase), putative 0.0016 0.0006 0.0027
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0159 0.2273
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0184 0.0518
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0145 0.0408
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.005 0.0185 0.0195
Echinococcus multilocularis GPCR, family 2 0.0017 0.0012 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Echinococcus multilocularis Smad4 0.0017 0.0011 0.0032
Onchocerca volvulus 0.0065 0.0266 0.1792
Brugia malayi Animal haem peroxidase family protein 0.0053 0.0205 0.1396
Giardia lamblia NADH oxidase lateral transfer candidate 0.005 0.0185 0.2661
Echinococcus multilocularis geminin 0.0693 0.3561 1
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0059 0.0231 0.0333
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1181
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0021 0.0133
Trypanosoma cruzi DNA polymerase eta, putative 0.0141 0.0665 0.0967
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0033
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0042 0.0146 0.0992
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0046 0.0438
Schistosoma mansoni chromobox protein 0.0154 0.0732 0.2057
Onchocerca volvulus Cathepsin F homolog 0.0057 0.0222 0.149
Loa Loa (eye worm) heterochromatin protein 1 0.0154 0.0732 0.4625
Brugia malayi Na,K-ATPase alpha subunit 0.0134 0.0628 0.43
Brugia malayi hypothetical protein 0.002 0.0027 0.0175
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0065 0.053
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0117 0.0328
Brugia malayi hypothetical protein 0.0112 0.0511 0.3499
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0055 0.0519
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0021 0.0059
Toxoplasma gondii NADPH-glutathione reductase 0.005 0.0185 0.0671
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0133
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0159 0.1575
Loa Loa (eye worm) hypothetical protein 0.0053 0.0202 0.1273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0051 0.0412
Echinococcus granulosus Na:K ATPase alpha subunit 0.0107 0.0487 0.1368
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0027 0.0218
Schistosoma mansoni ATPase 0.0204 0.0995 0.2795
Giardia lamblia Cathepsin B precursor 0.0018 0.0021 0.0229
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0027 0.0065 0.0234
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0042 0.0146 0.041
Echinococcus granulosus Smad4 0.0017 0.0011 0.0032
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0042
Entamoeba histolytica cysteine protease, putative 0.0018 0.0021 0.0229
Brugia malayi MH2 domain containing protein 0.0017 0.0011 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0099 0.0825
Brugia malayi calcium ATPase 0.0059 0.0231 0.1577
Echinococcus multilocularis cation transporting atpase worm 0.0042 0.0146 0.041
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0042 0.0146 0.0529
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0018 0.0021 0.0156
Brugia malayi intermediate filament protein 0.0027 0.0065 0.0436
Trypanosoma brucei protein kinase, putative 0.0051 0.0191 0.2204
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0046 0.0168
Loa Loa (eye worm) animal heme peroxidase 0.0053 0.0205 0.1294
Onchocerca volvulus Huntingtin homolog 0.0122 0.0565 0.3854
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0117 0.054 0.4612
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0063 0.0581
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0113 0.0161
Schistosoma mansoni transcription factor LCR-F1 0.0112 0.0511 0.1435
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0091 0.0402 0.05
Giardia lamblia Cathepsin B precursor 0.0018 0.0021 0.0229
Brugia malayi Cathepsin L-like precursor 0.0057 0.0222 0.1513
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0099 0.0825
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Onchocerca volvulus Huntingtin homolog 0.0122 0.0565 0.3854
Brugia malayi Cathepsin L-like precursor 0.0022 0.004 0.0263
Echinococcus multilocularis cpg binding protein 0.003 0.0083 0.0233
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0113 0.0948
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0144 0.0681 0.5829
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0184 0.0518
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0671
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0106 0.1486
Leishmania major phospholipid-transporting ATPase 1-like protein 0.0016 0.0006 0.0027
Brugia malayi calcium ATPase 0.0059 0.0234 0.1594
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Trypanosoma brucei glucosidase, putative 0.0036 0.0113 0.1295
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.054 0.6302
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0184 0.0518
Plasmodium falciparum serine repeat antigen 5 0.0018 0.0021 0.0156
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0113 0.0161
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0204 0.0995 0.2795
Echinococcus granulosus serotonin transporter 0.0292 0.1457 0.4092
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0191 0.0536
Entamoeba histolytica cysteine protease, putative 0.0018 0.0021 0.0229
Echinococcus granulosus lamin 0.0027 0.0065 0.0183
Giardia lamblia Hypothetical protein 0.0018 0.0021 0.0229
Loa Loa (eye worm) transbilayer Amphipath transporters family member 0.0016 0.0006 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0021 0.0156
Brugia malayi Associated with TFs and helicases family protein 0.0035 0.0106 0.0719
Trypanosoma brucei phospholipid-transporting ATPase, putative 0.0016 0.0006 0.0032
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0065 0.0436
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0018 0.0021 0.0229
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0134 0.0629 0.3972
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0018 0.0021 0.0156
Plasmodium falciparum amino acid transporter, putative 0.005 0.0184 0.1806
Toxoplasma gondii P-type ATPase4, putative 0.0134 0.0628 0.227
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0106 0.0385
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.005 0.0185 0.2142
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0714 0.1039
Loa Loa (eye worm) notch protein 0.0017 0.0015 0.0094
Loa Loa (eye worm) doublecortin family protein 0.002 0.0027 0.0172
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0277 0.1747
Brugia malayi EGF-like domain containing protein 0.0017 0.0015 0.009
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0041 0.0137 0.0385
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0063 0.0518
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0042 0.0146 0.123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.067
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0042 0.0146 0.0139
Brugia malayi Cytochrome P450 family protein 0.0026 0.0061 0.0407
Onchocerca volvulus 0.005 0.0184 0.1231
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0072 0.0811
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.054 0.6302
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0133
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0042 0.0146 0.014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0057 0.0222 0.1881
Onchocerca volvulus 0.0035 0.0106 0.0692
Giardia lamblia Cysteine protease 0.0018 0.0021 0.0229
Echinococcus multilocularis phospholipid transporting ATPase IA 0.0016 0.0006 0.0016
Leishmania major calcium-translocating P-type ATPase 0.0204 0.0995 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0364 0.1836 0.2516
Echinococcus multilocularis expressed conserved protein 0.0092 0.0408 0.1146
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Schistosoma mansoni biogenic amine (5HT) receptor 0.0159 0.0757 0.2125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0077 0.0634
Onchocerca volvulus Neurogenic locus notch homolog 0.0017 0.0015 0.0067
Plasmodium falciparum glutathione reductase 0.005 0.0185 0.1817
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.005 0.0185 0.014
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.046 0.1292
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.005 0.0184 0.0518
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0111 0.0929
Toxoplasma gondii cathepsin CPC2 0.0018 0.0021 0.0076
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0011 0.0032
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0021 0.0133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0111 0.0929
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0277 0.0777
Giardia lamblia Cathepsin B precursor 0.0018 0.0021 0.0229
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0105 0.0477 0.4073
Trypanosoma cruzi cation-transporting ATPase, putative 0.0042 0.0146 0.0209
Echinococcus granulosus bloom syndrome protein 0.0046 0.0168 0.0472
Plasmodium falciparum cysteine proteinase falcipain 1 0.0041 0.0137 0.1327
Schistosoma mansoni cathepsin F (C01 family) 0.0057 0.0222 0.0623
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0011 0.0032
Trichomonas vaginalis chromobox protein, putative 0.0154 0.0732 0.6269
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1378 0.7159 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Toxoplasma gondii proton ATPase, putative 0.0016 0.0006 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0106 0.0888
Trichomonas vaginalis Heterochromatin protein, putative 0.0035 0.0106 0.0888
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0041 0.0137 0.0196
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0059
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0106 0.0888
Trypanosoma cruzi phospholipid-translocating ATPase, putative 0.0016 0.0006 0.0004
Brugia malayi E1-E2 ATPase family protein 0.0042 0.0146 0.0992
Schistosoma mansoni rab6-interacting 0.002 0.0027 0.0077
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0091 0.0403 0.2741
Leishmania major cathepsin L-like protease 0.0057 0.0222 0.2207
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0091 0.0403 0.2548
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0113 0.0948
Leishmania major cysteine peptidase A (CPA) 0.0057 0.0222 0.2207
Entamoeba histolytica cysteine proteinase 1, putative 0.0041 0.0137 0.1943
Trypanosoma cruzi cysteine peptidase, putative 0.0041 0.0137 0.0196
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0113 0.0948
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0144 0.0681 0.1913
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0059 0.0231 0.1577
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0027 0.0065 0.009
Brugia malayi hypothetical protein 0.0027 0.0065 0.0432
Loa Loa (eye worm) hypothetical protein 0.0159 0.0757 0.4778
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0084 0.0235
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0671
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0185 0.0266
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0107 0.0487 0.0707
Giardia lamblia Cathepsin L precursor 0.0018 0.0021 0.0229
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0042 0.0146 0.0209
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.005 0.0184 0.0518
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.007 0.0292 0.0345
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0204 0.0995 0.0989
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0114 0.077
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0184 0.0518
Loa Loa (eye worm) hypothetical protein 0.0052 0.0195 0.1231
Echinococcus granulosus cysteine protease 0.0041 0.0137 0.0385
Onchocerca volvulus 0.0057 0.0222 0.149
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0106 0.1017
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0041 0.0137 0.0385
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.1164
Giardia lamblia Cathepsin B precursor 0.0018 0.0021 0.0229
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Entamoeba histolytica cysteine protease, putative 0.0018 0.0021 0.0229
Loa Loa (eye worm) hypothetical protein 0.003 0.0084 0.0528
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0113 0.0715
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0017 0.0015 0.0042
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.0439 0.1233
Echinococcus granulosus cpg binding protein 0.003 0.0083 0.0233
Loa Loa (eye worm) helicase 0.0035 0.0106 0.0671
Plasmodium vivax unspecified product 0.0018 0.0021 0.0156
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0069 0.0285 0.4135
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0105 0.0477 0.6976
Brugia malayi Cytochrome P450 family protein 0.0016 0.0007 0.0036
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0113 0.0948
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0051 0.0412
Trichomonas vaginalis MYB3r3, putative 0.0105 0.0477 0.4073
Brugia malayi CXXC zinc finger family protein 0.0029 0.0074 0.0499
Toxoplasma gondii cation-transporting ATPase, putative 0.0016 0.0006 0.0021
Echinococcus multilocularis neuropeptide s receptor 0.047 0.2391 0.6716
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0021 0.0156
Trypanosoma brucei calcium-translocating P-type ATPase 0.0177 0.0855 1
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0105 0.0477 0.4073
Trypanosoma cruzi P-type H+-ATPase, putative 0.0059 0.0231 0.0333
Loa Loa (eye worm) animal heme peroxidase 0.0053 0.0205 0.1294
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0159 0.1343
Onchocerca volvulus 0.0057 0.0222 0.149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.0137 0.1151
Entamoeba histolytica hypothetical protein 0.0035 0.0106 0.149
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0037 0.0116 0.0786
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0106 0.0299
Schistosoma mansoni cation-transporting atpase worm 0.0042 0.0146 0.041
Entamoeba histolytica cysteine proteinase, putative 0.0057 0.0222 0.32
Schistosoma mansoni lamin 0.0027 0.0065 0.0183
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0021 0.0133
Plasmodium vivax DNA repair protein REV1, putative 0.0028 0.0072 0.067
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0074 0.047
Brugia malayi hypothetical protein 0.0017 0.0014 0.0083
Leishmania major P-type H -ATPase, putative 0.0085 0.0372 0.3717
Brugia malayi glutathione reductase 0.0144 0.0678 0.4648
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0117 0.0541 0.1519
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0099 0.0825
Leishmania major P-type ATPase, putative 0.0117 0.0541 0.5421
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0399
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Entamoeba histolytica cysteine proteinase, putative 0.0041 0.0137 0.1943
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.005 0.0185 0.0266
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.054 0.6302
Onchocerca volvulus 0.0057 0.0222 0.149
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Plasmodium falciparum serine repeat antigen 9 0.0018 0.0021 0.0156
Trypanosoma brucei cation-transporting ATPase, putative 0.0042 0.0146 0.1681
Onchocerca volvulus 0.0083 0.0359 0.2435
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0144 0.0681 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0144 0.0678 0.1905
Echinococcus multilocularis phosphoserine phosphatase 0.0027 0.0065 0.0181
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0021 0.0133
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0091 0.0402 0.05
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0046 0.0412
Plasmodium falciparum serine repeat antigen 3 0.0018 0.0021 0.0156
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0159 0.1343
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0033
Giardia lamblia Cysteine protease 0.0018 0.0021 0.0229
Brugia malayi Animal haem peroxidase family protein 0.0053 0.0205 0.1396
Loa Loa (eye worm) hypothetical protein 0.0027 0.0065 0.0412
Echinococcus multilocularis protein patched 0.0042 0.0145 0.0408
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0059
Loa Loa (eye worm) hypothetical protein 0.0141 0.0665 0.4199
Brugia malayi CHE-14 protein 0.0042 0.0145 0.0985
Echinococcus multilocularis RUN 0.002 0.0027 0.0077
Echinococcus granulosus geminin 0.0693 0.3561 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0184 0.0667
Leishmania major DNA damage repair protein, putative 0.0028 0.0072 0.0696
Echinococcus multilocularis chromobox protein 1 0.0154 0.0732 0.2057
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.0439 0.1233
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0006 0.0023
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.0439 0.6417
Leishmania major cathepsin L-like protease 0.0057 0.0222 0.2207
Schistosoma mansoni sodium/chloride dependent transporter 0.0292 0.1457 0.4092
Echinococcus granulosus phospholipid transporting atpase ih 0.0016 0.0006 0.0016
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0072 0.0811
Plasmodium falciparum serine repeat antigen 7 0.0018 0.0021 0.0156
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0287 0.3337
Schistosoma mansoni notch 0.0017 0.0015 0.0042
Giardia lamblia Cathepsin B precursor 0.0018 0.0021 0.0229
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0027 0.0077
Brugia malayi EGF-like domain containing protein 0.0017 0.0015 0.009
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.0026 0.0059 0.0795
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.1016 0.6416
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0191 0.0536
Loa Loa (eye worm) hypothetical protein 0.0049 0.018 0.1136
Loa Loa (eye worm) hypothetical protein 0.0049 0.0183 0.1155
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0007 0.0047
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0144 0.0681 0.7964
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0063 0.0088
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0059
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0042 0.0146 0.0139
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0277 0.0777
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0061 0.0385
Echinococcus multilocularis cathepsin L cysteine protease 0.0057 0.0222 0.0623
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0018 0.0021 0.0156
Echinococcus multilocularis serotonin receptor 0.0159 0.0757 0.2125
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.054 0.6302
Schistosoma mansoni atpase class VI type 11c 0.0027 0.0065 0.0181
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.046 0.1292
Trichomonas vaginalis cation-transporting ATPase, putative 0.0204 0.0995 0.8526
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0021 0.0027
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0125 0.1047
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0134 0.0628 0.3962
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Schistosoma mansoni DNA polymerase IV / kappa 0.0028 0.0072 0.0202
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0133
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0027 0.0077
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0252
Entamoeba histolytica cysteine protease, putative 0.0057 0.0222 0.32
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0144 0.0681 0.5829
Trichomonas vaginalis pc-MYB2, putative 0.0105 0.0477 0.4073
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0003 0.0008
Schistosoma mansoni phospholipid-transporting atpase 1 (aminophospholipid flippase 1) 0.0016 0.0006 0.0016
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0117 0.0541 0.1519
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1378 0.7159 1
Loa Loa (eye worm) hypothetical protein 0.0083 0.0359 0.2267
Brugia malayi Cathepsin L-like precursor 0.0057 0.0222 0.1513
Loa Loa (eye worm) hypothetical protein 0.0292 0.1457 0.9199
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0222 0.1881
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0222 0.1881
Loa Loa (eye worm) hypothetical protein 0.0236 0.1161 0.7332
Plasmodium falciparum cysteine proteinase falcipain 3 0.0057 0.0222 0.2185
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0063 0.0228
Loa Loa (eye worm) hypothetical protein 0.0069 0.0285 0.18
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0016 0.0006 0.0004
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0204 0.0995 0.2795
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0027 0.0077
Giardia lamblia Cathepsin B precursor 0.0018 0.0021 0.0229
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0359 0.2456
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0021 0.0156
Brugia malayi Smad1 0.0017 0.0011 0.0066
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0057 0.0222 0.1401
Brugia malayi Cathepsin L-like precursor 0.0057 0.0222 0.1513
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0145 0.0917
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0144 0.0681 0.1913
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0176 0.1201
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0086 0.0374 0.5454
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0015 0.009
Schistosoma mansoni ATPase 0.0204 0.0995 0.2795
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.009 0.0394 0.1107
Onchocerca volvulus 0.0124 0.0576 0.3933
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0102 0.046 0.1292
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0065 0.0412
Treponema pallidum cation-transporting ATPase, P-type 0.0042 0.0146 0.01
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0113 0.0948
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0059 0.0231 0.0333
Onchocerca volvulus 0.0124 0.0576 0.3933
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0006 0.0023
Toxoplasma gondii EGF family domain-containing protein 0.0017 0.0015 0.0054
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0133
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0191 0.069
Echinococcus granulosus biogenic amine 5HT receptor 0.0159 0.0757 0.2125
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0006 0.0023
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0159 0.1835
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0091 0.0402 0.275
Loa Loa (eye worm) animal heme peroxidase 0.0053 0.0205 0.1294
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0144 0.0681 0.0991
Schistosoma mansoni terminal deoxycytidyl transferase 0.0091 0.0401 0.1125
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0111 0.1092
Toxoplasma gondii melibiase subfamily protein 0.0102 0.046 0.1664
Plasmodium vivax P-type ATPase4, putative 0.0204 0.0995 1
Schistosoma mansoni hypothetical protein 0.0112 0.0511 0.1435
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0021 0.0156
Loa Loa (eye worm) phospholipid-transporting ATPase ID 0.0016 0.0006 0.0036
Schistosoma mansoni alpha-glucosidase 0.014 0.0658 0.1847
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.005 0.0184 0.0518
Loa Loa (eye worm) hypothetical protein 0.0124 0.0576 0.364
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0021 0.0059
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.005 0.0184 0.1255
Schistosoma mansoni hypothetical protein 0.0693 0.3561 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0145 0.0917
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0277 0.0777
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0003 0.0019
Onchocerca volvulus 0.0053 0.0205 0.1372
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0037 0.0116 0.0786
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0042 0.0146 0.0139
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.067
Loa Loa (eye worm) hypothetical protein 0.0122 0.0565 0.3568
Loa Loa (eye worm) RecQ helicase 0.0046 0.0168 0.1062
Onchocerca volvulus 0.0057 0.0222 0.149
Trypanosoma cruzi major cysteine proteinase, putative 0.0112 0.0513 0.0746
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0106 0.0299
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0671
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0021 0.0213
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0021 0.0133
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0018 0.0021 0.0156
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0115 0.0323
Trypanosoma brucei DNA polymerase IV, putative 0.0111 0.0505 0.5897
Trichomonas vaginalis DNA polymerase eta, putative 0.0117 0.054 0.4612
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0221 0.1876
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0021 0.0106
Echinococcus granulosus lamin dm0 0.0027 0.0065 0.0183
Schistosoma mansoni cathepsin s 0.0022 0.004 0.0112
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0241 0.1188 0.7502
Trypanosoma brucei unspecified product 0.0111 0.0505 0.5897
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0144 0.0681 0.5829
Schistosoma mansoni loxhd1 0.002 0.0027 0.0077
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0541 0.2765 1
Brugia malayi Heterochromatin protein 1 0.0154 0.0732 0.5022
Schistosoma mansoni alpha glucosidase 0.0036 0.0113 0.0318
Trichomonas vaginalis hypothetical protein 0.0035 0.0106 0.0888
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0204 0.0995 0.2795
Trypanosoma cruzi proton motive ATPase 1, putative 0.0027 0.0065 0.009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0133
Echinococcus granulosus cathepsin L cysteine protease 0.0041 0.0137 0.0385
Schistosoma mansoni hypothetical protein 0.0036 0.0114 0.032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0051 0.0413
Echinococcus granulosus neuropeptide receptor A26 0.047 0.2391 0.6716
Leishmania major DNA polymerase eta, putative 0.0141 0.0665 0.6673
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0072 0.0101
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0063 0.0707
Loa Loa (eye worm) hypothetical protein 0.0019 0.0025 0.0157
Brugia malayi Peroxidasin 0.0053 0.0205 0.1396
Brugia malayi Papain family cysteine protease containing protein 0.0041 0.0137 0.0929
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1181
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Echinococcus granulosus slit 2 protein 0.0017 0.0015 0.0042
Echinococcus granulosus cation transporting atpase worm 0.0042 0.0146 0.041
Trypanosoma brucei DNA damage repair protein, putative 0.0028 0.0072 0.0811
Brugia malayi cathepsin L precursor 0.0018 0.0021 0.0133
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.005 0.0184 0.0518
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0328 0.1644 0.2246
Onchocerca volvulus 0.0057 0.0222 0.149
Entamoeba histolytica cysteine proteinase, putative 0.0041 0.0137 0.1943
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Echinococcus multilocularis neurogenic locus notch protein 0.0017 0.0015 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0028 0.0072 0.0101
Schistosoma mansoni phospholipid-transporting atpase 0.0016 0.0006 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Echinococcus granulosus neurogenic locus notch protein 0.0017 0.0015 0.0042
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0042 0.0146 0.2079
Leishmania major cathepsin L-like protease 0.015 0.0714 0.7169
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0042 0.0146 0.2079
Schistosoma mansoni chromobox protein 0.0154 0.0732 0.2057
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.054 0.0784
Schistosoma mansoni microtubule-associated protein tau 0.0688 0.3534 0.9925
Loa Loa (eye worm) animal heme peroxidase 0.0053 0.0205 0.1294
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0183 0.0514
Schistosoma mansoni sodium/chloride dependent transporter 0.005 0.0187 0.0525
Onchocerca volvulus 0.0063 0.0253 0.1705
Entamoeba histolytica hypothetical protein 0.0035 0.0106 0.149
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0027 0.0077
Schistosoma mansoni hypothetical protein 0.0408 0.2064 0.5796
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0277 0.0777
Brugia malayi RNA binding protein 0.0067 0.0277 0.1889
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.005 0.0185 0.1817
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0084 0.0235
Echinococcus granulosus peroxidasin 0.0053 0.0205 0.0575
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0111 0.0929
Entamoeba histolytica hypothetical protein 0.0018 0.0021 0.0229
Trypanosoma cruzi cysteine peptidase, putative 0.015 0.0714 0.1039
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.005 0.0185 0.014
Treponema pallidum NADH oxidase 0.005 0.0185 0.014
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0021 0.0183
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0084 0.0302
Trypanosoma cruzi cysteine protease, putative 0.0041 0.0137 0.0196
Brugia malayi Membrane calcium atpase protein 3 0.0117 0.0541 0.3704
Schistosoma mansoni chromobox protein 0.0035 0.0106 0.0299
Echinococcus granulosus X box binding protein 1 0.0287 0.1431 0.402
Echinococcus granulosus cation transporting ATPase 13A1 0.0042 0.0146 0.041
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.005 0.0185 0.0521
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Brugia malayi Animal haem peroxidase family protein 0.0053 0.0205 0.1396
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.014 0.1181
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0287 0.3337
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Schistosoma mansoni hypothetical protein 0.0041 0.0137 0.0385
Echinococcus granulosus dna polymerase eta 0.0141 0.0665 0.1868
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0106 0.149
Plasmodium vivax copper-transporting ATPase, putative 0.0042 0.0146 0.142
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0021 0.0059
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0222 0.1881
Brugia malayi Cathepsin L-like precursor 0.0035 0.0106 0.0717
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0051 0.0413
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0084 0.0235
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0144 0.0681 0.5829
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0111 0.0929
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0059 0.0231 0.146
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0057 0.0222 0.2185
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1181
Loa Loa (eye worm) calcium ATPase 0.0026 0.0059 0.0375
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0359 0.1008
Trichomonas vaginalis chromobox protein, putative 0.0097 0.0435 0.3716
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0191 0.0274
Echinococcus multilocularis notch 0.0017 0.0015 0.0042
Plasmodium vivax heterochromatin protein 1, putative 0.0035 0.0106 0.1017
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0091 0.0401 0.1125
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.005 0.0184 0.0518
Echinococcus granulosus copper transporting ATPase 1 0.0042 0.0146 0.041
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0177 0.0855 0.24
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0541 0.2765 0.2731
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0016 0.0006 0.0023
Echinococcus multilocularis neuropeptide receptor A26 0.047 0.2391 0.6716
Brugia malayi ImpB/MucB/SamB family protein 0.0141 0.0665 0.4558
Giardia lamblia Cathepsin L precursor 0.0018 0.0021 0.0229
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.005 0.0185 0.0521
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0022 0.0221
Echinococcus granulosus calcium transporting atpase 0.0177 0.0855 0.24
Echinococcus multilocularis X box binding protein 1 0.0287 0.1431 0.402
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0035 0.0106 0.1017
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0106 0.0888
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0184 0.1164
Echinococcus granulosus cathepsin l1 0.0057 0.0222 0.0623
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0084 0.0235
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0281 0.079
Loa Loa (eye worm) hypothetical protein 0.0022 0.004 0.0252
Loa Loa (eye worm) hypothetical protein 0.0204 0.0995 0.6283
Echinococcus multilocularis phosphoserine phosphatase 0.0027 0.0065 0.0181
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.014 0.1181
Brugia malayi cathepsin L-like precursor 0.0035 0.0106 0.0717
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0006 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.054 0.6302
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0328 0.1644 0.2246
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0065 0.053
Echinococcus multilocularis phosphoserine phosphatase 0.0027 0.0065 0.0181
Echinococcus multilocularis phosphoserine phosphatase 0.0027 0.0065 0.0181
Trypanosoma brucei unspecified product 0.0063 0.0253 0.2932
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Brugia malayi Doublecortin family protein 0.002 0.0027 0.0175
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0113 0.1112
Loa Loa (eye worm) calcium ATPase 0.0086 0.0374 0.2362
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0057 0.0222 0.0623
Plasmodium falciparum serine repeat antigen 2 0.0018 0.0021 0.0156
Echinococcus granulosus expressed conserved protein 0.0092 0.0408 0.1146
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Loa Loa (eye worm) cysteine protease 0.0057 0.0222 0.1401
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0011 0.0071
Brugia malayi ImpB/MucB/SamB family protein 0.0091 0.0401 0.2741
Onchocerca volvulus 0.0057 0.0222 0.149
Schistosoma mansoni cathepsin F (C01 family) 0.0057 0.0222 0.0623
Giardia lamblia Cathepsin B precursor 0.0018 0.0021 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0403 0.3442
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0117 0.0541 0.1519
Trichomonas vaginalis MYB, putative 0.0106 0.048 0.4096
Echinococcus multilocularis protein jagged 2 0.0017 0.0015 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0106 0.0888
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0042 0.0146 0.2079
Echinococcus granulosus sodium and chloride dependent glycine 0.005 0.0184 0.0518
Echinococcus multilocularis neurogenic locus notch protein 0.0017 0.0015 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0065 0.0266 0.0746
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0057 0.0222 0.2185
Giardia lamblia Cathepsin B precursor 0.0018 0.0021 0.0229
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0016 0.0006 0.0023
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.046 0.1292
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0025 0.0159
Echinococcus multilocularis lamin dm0 0.0027 0.0065 0.0183
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.009 0.0394 0.1107
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0042 0.0146 0.041
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0328 0.1644 0.2246
Schistosoma mansoni survival motor neuron protein 0.0048 0.0176 0.0496
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.1164
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0159 0.0228
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0144 0.0681 0.2464
Entamoeba histolytica deoxycytidyl transferase, putative 0.0091 0.0401 0.5845
Schistosoma mansoni lipoxygenase 0.002 0.0027 0.0077
Brugia malayi Delta serrate ligand family protein 0.0017 0.0015 0.009
Brugia malayi Animal haem peroxidase family protein 0.0053 0.0205 0.1396
Echinococcus multilocularis protein jagged 1 0.0017 0.0015 0.0042
Schistosoma mansoni Smad4 0.0017 0.0011 0.0032
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0016 0.0006 0.0023
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0115 0.0726
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0281 0.079
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0011 0.0071
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0277 0.0777
Brugia malayi Cadherin domain containing protein 0.0017 0.0015 0.009
Echinococcus multilocularis neurogenic locus notch protein 4 0.0017 0.0015 0.0042
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0923
Onchocerca volvulus 0.002 0.0027 0.0149
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0222 0.1881
Trypanosoma brucei phospholipid-transporting ATPase 1-like protein, putative 0.0016 0.0006 0.0032
Brugia malayi MH2 domain containing protein 0.0017 0.0011 0.0066
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0046 0.0039
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0106 0.0888
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0035 0.0106 0.0385
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Schistosoma mansoni DNA polymerase eta 0.0141 0.0665 0.1868
Plasmodium falciparum serine repeat antigen 6 0.0018 0.0021 0.0156
Brugia malayi Protein cec-1. 0.0035 0.0106 0.0719
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0021 0.0076
Onchocerca volvulus Cathepsin L homolog 0.0057 0.0222 0.149
Leishmania major acetoin dehydrogenase e3 component-like protein 0.005 0.0185 0.1839
Treponema pallidum sodium- and chloride- dependent transporter 0.0292 0.1457 0.1417
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0159 0.0228
Giardia lamblia Cysteine protease 0.0018 0.0021 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Leishmania major cathepsin L-like protease 0.015 0.0714 0.7169
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0021 0.0133
Loa Loa (eye worm) hypothetical protein 0.0068 0.0281 0.1777
Leishmania major cytochrome p450-like protein 0.0016 0.0007 0.0041
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0018 0.0021 0.0156
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0021 0.0133
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0042
Mycobacterium ulcerans hypothetical protein 0.0028 0.0072 0.0065
Echinococcus granulosus dnaJ subfamily B 0.0408 0.2064 0.5796
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0191 0.1613
Echinococcus multilocularis slit 2 protein 0.0017 0.0015 0.0042
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0105 0.0477 0.6976
Brugia malayi Papain family cysteine protease containing protein 0.0057 0.0222 0.1513
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0018 0.0021 0.0156
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.066 0.1854
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0021 0.0156
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1181
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0046 0.0511
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.004 0.0263
Schistosoma mansoni notch 0.0017 0.0015 0.0042
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0021 0.0027
Brugia malayi Pre-SET motif family protein 0.003 0.0084 0.0562
Entamoeba histolytica cysteine protease, putative 0.0018 0.0021 0.0229
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.005 0.0185 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0106 0.0888
Trypanosoma cruzi cysteine proteinase, putative 0.0041 0.0137 0.0196
Schistosoma mansoni chromobox protein 0.0035 0.0106 0.0299
Onchocerca volvulus Peroxidasin homolog 0.0053 0.0205 0.1372
Plasmodium vivax unspecified product 0.0041 0.0137 0.1327
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0021 0.0156
Trichomonas vaginalis DNA helicase recq1, putative 0.0046 0.0168 0.142
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0042 0.0146 0.123
Trypanosoma brucei trypanothione reductase 0.0144 0.0678 0.7928
Plasmodium falciparum serine repeat antigen 1 0.0018 0.0021 0.0156
Trypanosoma brucei chrX additional, unordered contigs 0.0028 0.0072 0.0811
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0091 0.0401 0.1125
Brugia malayi EGF-like domain containing protein 0.0017 0.0015 0.009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0059
Plasmodium falciparum heterochromatin protein 1 0.0035 0.0106 0.1017
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0091 0.0401 0.1125
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0012 0.007
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0057 0.0222 0.0623
Leishmania major P-type H -ATPase, putative 0.0085 0.0372 0.3717
Plasmodium falciparum copper-transporting ATPase 0.0042 0.0146 0.142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.014 0.1181
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0191 0.0274
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0191 0.1892
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.005 0.0185 0.1839
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0113 0.0766
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0277 0.0777
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.005 0.0184 0.0518
Echinococcus multilocularis protein dispatched 1 0.0048 0.0176 0.0495
Plasmodium vivax calcium-transporting ATPase, putative 0.0204 0.0995 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0021 0.0156
Toxoplasma gondii cation-transporting atpase family protein 0.0027 0.0065 0.0234
Schistosoma mansoni cpg binding protein 0.003 0.0083 0.0233
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0292 0.1457 0.4092
Toxoplasma gondii P-type ATPase PMA1 0.0085 0.0372 0.1345
Leishmania major cathepsin L-like protease 0.0057 0.0222 0.2207
Plasmodium vivax glutathione reductase, putative 0.0144 0.0678 0.6797
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0051 0.0413
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0059 0.0231 0.0837
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0113 0.0948
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0007 0.0006
Trypanosoma brucei calcium-transporting ATPase, putative 0.0064 0.0261 0.3035
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.005 0.0184 0.1164
Loa Loa (eye worm) Notch2 0.0017 0.0015 0.0094
Brugia malayi Blistered cuticle protein 3 0.0053 0.0205 0.1396
Schistosoma mansoni DNA helicase recq1 0.0019 0.0025 0.007
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0042
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0107 0.0487 0.1368
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Onchocerca volvulus 0.002 0.0027 0.0149
Onchocerca volvulus 0.0018 0.0021 0.0106
Echinococcus granulosus phospholipid transporting ATPase IA 0.0016 0.0006 0.0016
Giardia lamblia Cathepsin L precursor 0.0018 0.0021 0.0229
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0184 0.0667
Entamoeba histolytica cysteine proteinase, putative 0.0041 0.0137 0.1943
Plasmodium vivax vivapain-3 0.0041 0.0137 0.1327
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0025 0.009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.0125 0.1045
Trichomonas vaginalis chromobox protein, putative 0.0097 0.0435 0.3716
Entamoeba histolytica hypothetical protein 0.0112 0.0511 0.7479
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0159 0.0447
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0113 0.1592
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0021 0.0156
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0059
Onchocerca volvulus 0.0053 0.0205 0.1372
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0159 0.1575
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0292 0.1457 1
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0042 0.0146 0.014
Trichomonas vaginalis cation-transporting ATPase, putative 0.0016 0.0006 0.0023
Entamoeba histolytica cysteine protease, putative 0.0018 0.0021 0.0229
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0128 0.0598 0.087
Onchocerca volvulus Slit protein homolog 0.0017 0.0015 0.0063
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0144 0.0681 0.7964
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0012 0.0075
Leishmania major trypanothione reductase 0.0144 0.0678 0.6806
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0191 0.0536
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0105 0.0477 0.6976
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.1164
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.1164
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0099 0.0825
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0099 0.0825
Onchocerca volvulus 0.0057 0.0222 0.149
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0191 0.2739
Echinococcus granulosus cation transporting ATPase 13A3 0.0042 0.0146 0.041
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0159 0.2273
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0021 0.0229
Entamoeba histolytica cysteine proteinase 2 0.0041 0.0137 0.1943
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0021 0.0156
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0117 0.0541 0.1956
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.005 0.0185 0.0266
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0046 0.0168
Echinococcus granulosus neural cadherin 0.0017 0.0015 0.0042
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0113 0.041
Schistosoma mansoni slit 0.0017 0.0015 0.0042
Loa Loa (eye worm) serotonin transporter b 0.0292 0.1457 0.9199
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0119 0.0547 0.0795
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0035 0.0106 0.0299
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.005 0.0184 0.0139
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0364 0.1836 0.2516
Trypanosoma brucei DNA polymerase kappa, putative 0.0069 0.0287 0.3337
Echinococcus granulosus notch 0.0017 0.0015 0.0042
Schistosoma mansoni hypothetical protein 0.002 0.0027 0.0077
Giardia lamblia High cysteine protein 0.0017 0.0015 0.0135
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0202 0.1373
Trichomonas vaginalis cation-transporting ATPase, putative 0.0144 0.0681 0.5829
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0134 0.0628 0.0621
Trichomonas vaginalis cation-transporting ATPase, putative 0.0085 0.0372 0.3169
Onchocerca volvulus 0.0017 0.0015 0.0063
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0025 0.0157
Trichomonas vaginalis DNA helicase recq, putative 0.0046 0.0168 0.142
Echinococcus multilocularis protein jagged 1 0.0017 0.0015 0.0042
Giardia lamblia DNA damage repair protein 0.0028 0.0072 0.0982
Loa Loa (eye worm) hypothetical protein 0.0063 0.0253 0.1599
Trypanosoma cruzi cruzipain precursor, putative 0.1319 0.6849 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0222 0.1881
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0042 0.0146 0.041
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0309 0.0869
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.046 0.1292
Brugia malayi E1-E2 ATPase family protein 0.0085 0.0372 0.2543
Trichomonas vaginalis cation-transporting ATPase, putative 0.0204 0.0995 0.8526
Loa Loa (eye worm) hypothetical protein 0.0043 0.015 0.0946
Trypanosoma brucei DNA polymerase kappa, putative 0.0055 0.0211 0.2444
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0106 0.0888
Trypanosoma cruzi trypanothione reductase, putative 0.0144 0.0678 0.0986
Schistosoma mansoni polycystin 1-related 0.002 0.0027 0.0077
Schistosoma mansoni cpg binding protein 0.0029 0.0074 0.0209
Brugia malayi MH2 domain containing protein 0.0244 0.1203 0.8257
Schistosoma mansoni phosphoserine phosphatase 0.0027 0.0065 0.0181
Loa Loa (eye worm) hypothetical protein 0.0134 0.0628 0.3962
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.015 0.0714 0.8351
Echinococcus multilocularis musashi 0.0027 0.0065 0.0183
Entamoeba histolytica cysteine proteinase, putative 0.0057 0.0222 0.32
Schistosoma mansoni cation-transporting atpase worm 0.0042 0.0146 0.041
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0091 0.0402 0.0395
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0015 0.009
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0107 0.0487 0.7126
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0177 0.0855 0.5861
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.1164
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.004 0.0263
Echinococcus multilocularis cation transporting ATPase 13A3 0.0042 0.0146 0.041
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0144 0.0678 0.0888
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0191 0.1204
Echinococcus multilocularis calcium transporting atpase 0.0177 0.0855 0.24
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0075 0.032 0.219
Leishmania major calcium motive p-type ATPase, putative 0.0107 0.0487 0.488
Toxoplasma gondii hypothetical protein 0.005 0.0184 0.0667
Schistosoma mansoni hypothetical protein 0.0287 0.1431 0.402
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0111 0.0929
Trypanosoma brucei calcium-transporting ATPase, putative 0.0016 0.0006 0.0032
Schistosoma mansoni notch 0.0017 0.0015 0.0042
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0215 0.0776
Giardia lamblia Cysteine protease 0.0018 0.0021 0.0229
Echinococcus multilocularis dnaJ subfamily B 0.0408 0.2064 0.5796
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0144 0.0681 0.5829
Echinococcus granulosus dna polymerase kappa 0.0117 0.054 0.1516
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.0106 0.0888
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0003 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0106 0.0888
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0016 0.0006 0.0023
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0046 0.0412
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0012 0.007
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0042 0.0146 0.0529
Echinococcus multilocularis cathepsin b 0.0018 0.0021 0.0059
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0021 0.0059
Schistosoma mansoni hypothetical protein 0.0041 0.0137 0.0385
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0018 0.0021 0.0156
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Schistosoma mansoni cell polarity protein 0.0017 0.0015 0.0042
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0099 0.0358
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0042
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.005 0.0185 0.0671
Echinococcus granulosus uncharacterized sodium dependent transporter 0.005 0.0184 0.0518
Toxoplasma gondii P-type ATPase of unknown pump specificity (type V) protein 0.0016 0.0006 0.0021
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.054 0.6302
Onchocerca volvulus Cathepsin L homolog 0.0057 0.0222 0.149
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.067
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0204 0.0995 0.2795
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0035 0.0106 0.1017
Echinococcus granulosus RUN 0.002 0.0027 0.0077
Schistosoma mansoni lamin 0.0027 0.0065 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0106 0.0888
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0106 0.0888
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0113 0.1592
Schistosoma mansoni peroxidasin 0.0053 0.0205 0.0575
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0144 0.0681 0.0991
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0112 0.0511 0.1435
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0051 0.0412
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0035 0.038
Onchocerca volvulus 0.0029 0.0074 0.0473
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0065 0.0412
Schistosoma mansoni cation-transporting atpase worm 0.0016 0.0006 0.0016
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0017 0.0015 0.0063
Echinococcus multilocularis phospholipid transporting atpase ih phospholipid transporting atpase if 0.0016 0.0006 0.0016
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.192 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0133
Trypanosoma cruzi DNA polymerase eta, putative 0.0079 0.0336 0.0487
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0105 0.0477 0.4073
Schistosoma mansoni phospholipid-transporting atpase 0.0016 0.0006 0.0016
Leishmania major cathepsin L-like protease 0.015 0.0714 0.7169
Plasmodium vivax SET domain protein, putative 0.003 0.0084 0.0787
Plasmodium falciparum serine repeat antigen 4 0.0018 0.0021 0.0156
Entamoeba histolytica hypothetical protein 0.0112 0.0511 0.7479
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0111 0.0158
Trichomonas vaginalis C-MYB, putative 0.0105 0.0477 0.4073
Loa Loa (eye worm) hypothetical protein 0.005 0.0184 0.1164
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0021 0.0156
Trypanosoma cruzi DNA polymerase kappa, putative 0.0117 0.054 0.0784
Giardia lamblia DINP protein human, muc B family 0.0097 0.0435 0.6356
Giardia lamblia Hypothetical protein 0.0018 0.0021 0.0229
Loa Loa (eye worm) hypothetical protein 0.0053 0.0205 0.1294
Brugia malayi hypothetical protein 0.0124 0.0577 0.3954
Entamoeba histolytica cysteine protease, putative 0.0018 0.0021 0.0229
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0117 0.0541 0.1519
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0018 0.0021 0.0156
Leishmania major cathepsin L-like protease 0.0057 0.0222 0.2207
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0403 0.3442
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0021 0.0059
Brugia malayi Calcium binding EGF domain containing protein 0.0017 0.0015 0.009
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0309 0.0869
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0042 0.0146 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0117 0.054 0.6302
Plasmodium falciparum DNA repair protein REV1, putative 0.0028 0.0072 0.067
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0012 0.0033
Brugia malayi follicle stimulating hormone receptor 0.0241 0.1188 0.8153
Schistosoma mansoni hypothetical protein 0.0017 0.0015 0.0042
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0027 0.0077
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.005 0.0185 0.1817
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0107 0.0487 0.7126
Brugia malayi EGF-like domain containing protein 0.0017 0.0015 0.009
Brugia malayi MAP kinase sur-1 0.0051 0.0191 0.1298
Echinococcus multilocularis phosphoserine phosphatase 0.0027 0.0065 0.0181
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0072 0.0811
Echinococcus granulosus neurogenic locus protein delta 0.0017 0.0015 0.0042
Leishmania major proton motive ATPase, putative 0.0042 0.0146 0.1443
Onchocerca volvulus Peroxidase homolog 0.0053 0.0205 0.1372
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0204 0.0995 0.1449
Loa Loa (eye worm) hypothetical protein 0.0042 0.0146 0.0923
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0042 0.0146 0.0139
Schistosoma mansoni hypothetical protein 0.0041 0.0137 0.0385
Schistosoma mansoni sodium-dependent amino acid transporter 0.005 0.0184 0.0518
Loa Loa (eye worm) hypothetical protein 0.0316 0.1584 1
Echinococcus granulosus fibropellin Ia 0.0017 0.0015 0.0042
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.0106 0.0888
Loa Loa (eye worm) hypothetical protein 0.0124 0.0577 0.3644
Loa Loa (eye worm) transcription factor SMAD2 0.0244 0.1203 0.7598
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0145 0.0408
Entamoeba histolytica cysteine protease, putative 0.0041 0.0137 0.1943
Brugia malayi Bloom's syndrome protein homolog 0.0046 0.0168 0.1144
Onchocerca volvulus 0.0237 0.1167 0.8004
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0106 0.0479 0.1734
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0396
Schistosoma mansoni hypothetical protein 0.0048 0.0176 0.0496
Giardia lamblia Cathepsin L-like protease 0.0018 0.0021 0.0229
Onchocerca volvulus 0.0027 0.0065 0.041
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0021 0.0229
Plasmodium falciparum glutathione reductase 0.0144 0.0678 0.6797
Echinococcus granulosus delta-like protein 1 0.0017 0.0015 0.0042
Schistosoma mansoni rab6-interacting 0.002 0.0027 0.0077
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0021 0.0133
Brugia malayi Cathepsin L-like precursor 0.0057 0.0222 0.1513
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0035 0.0106 0.0299
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0541 0.2765 0.3821
Plasmodium falciparum serine repeat antigen 8 0.0018 0.0021 0.0156
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.192 1 1
Schistosoma mansoni smad 0.0017 0.0011 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0221 0.1876
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0115 0.0323
Plasmodium vivax vivapain-2 0.0057 0.0222 0.2185
Brugia malayi hypothetical protein 0.0053 0.0205 0.1396
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0035 0.0106 0.0719
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0222 0.1881
Giardia lamblia Encystation-specific protease 0.0018 0.0021 0.0229
Plasmodium falciparum transporter, putative 0.005 0.0184 0.1806
Schistosoma mansoni sodium/chloride dependent transporter 0.005 0.0184 0.0518
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0051 0.0413
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0204 0.0995 0.3599
Schistosoma mansoni notch 0.0017 0.0015 0.0042
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0046 0.0039
Schistosoma mansoni alpha-glucosidase 0.014 0.0658 0.1847
Brugia malayi Glycosyl hydrolases family 31 protein 0.0162 0.0776 0.5324
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0105 0.0477 0.6976
Toxoplasma gondii cathepsin CPC1 0.0018 0.0021 0.0076
Echinococcus multilocularis serotonin transporter 0.0292 0.1457 0.4092
Plasmodium vivax amine transporter, putative 0.005 0.0184 0.1806
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0021 0.0229
Echinococcus granulosus tar DNA binding protein 0.0067 0.0277 0.0777
Brugia malayi SET domain containing protein 0.0036 0.0115 0.0781
Brugia malayi Muscle positioning protein 4 0.0017 0.0015 0.009
Echinococcus granulosus Chromobox protein 3 0.0035 0.0106 0.0299
Brugia malayi Sodium:neurotransmitter symporter family protein 0.005 0.0184 0.1255
Trypanosoma cruzi copper-transporting ATPase, putative 0.0027 0.0065 0.009
Onchocerca volvulus 0.0048 0.0176 0.1177
Schistosoma mansoni cpg binding protein 0.003 0.0083 0.0233
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0144 0.0681 0.6837
Schistosoma mansoni peroxidasin 0.0053 0.0205 0.0575
Echinococcus granulosus cathepsin l1 0.0035 0.0106 0.0298
Onchocerca volvulus 0.0027 0.0065 0.041
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0055 0.0605
Trypanosoma brucei phospholipid-translocating P-type ATPase (flippase), putative 0.0016 0.0006 0.0032
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.005 0.0184 0.0518
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0021 0.0156
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0021 0.0229
Loa Loa (eye worm) thioredoxin reductase 0.0144 0.0678 0.4282
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0159 0.1082
Trypanosoma cruzi cysteine proteinase, putative 0.0041 0.0137 0.0196
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0107 0.0487 0.1368
Mycobacterium tuberculosis Probable reductase 0.0328 0.1644 0.2246
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0117 0.0541 0.1519
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0177 0.0855 0.24
Onchocerca volvulus Peroxidasin homolog 0.0053 0.0205 0.1372
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0094
Trypanosoma cruzi phospholipid-transporting ATPase 1-like protein, putative 0.0016 0.0006 0.0004
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0035 0.0106 0.0385
Trichomonas vaginalis mercuric reductase, putative 0.005 0.0185 0.1568
Trypanosoma cruzi DNA damage repair protein, putative 0.0028 0.0072 0.0101
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0021 0.0059
Echinococcus multilocularis cathepsin L 0.0018 0.0021 0.0059
Schistosoma mansoni smad1 5 8 and 0.0017 0.0011 0.0032
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0042 0.0146 0.014
Echinococcus granulosus protein jagged 1 0.0017 0.0015 0.0042
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0134 0.0628 0.1762
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0025 0.0159
Loa Loa (eye worm) hypothetical protein 0.0035 0.0106 0.0671
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0134 0.0628 0.9205
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0091 0.0401 0.2529
Brugia malayi fibroinase precursor 0.0018 0.0021 0.0133
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.005 0.0184 0.0667
Mycobacterium tuberculosis Conserved hypothetical protein 0.0091 0.0401 0.0498
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0027 0.0077
Leishmania major calcium-transporting ATPase, putative 0.0107 0.0487 0.488
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0125 0.1045
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0021 0.0059
Echinococcus granulosus chromobox protein 2 0.0035 0.0106 0.0299
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0091 0.0402 0.2538
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0541 0.2765 0.276
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0113 0.0948
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0033
Brugia malayi notch-like transmembrane receptor 0.0017 0.0015 0.009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0159 0.1343
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0105 0.0477 0.4073
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0079 0.0336 0.1217
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0011 0.0032
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0042 0.0146 0.014
Schistosoma mansoni hypothetical protein 0.0017 0.0012 0.0033
Schistosoma mansoni notch 0.0017 0.0015 0.0043
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0003 0.0008
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0185 0.0266
Echinococcus multilocularis Chromo domain 0.0035 0.0106 0.0299
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0021 0.0156
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0027 0.0065 0.0181
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0027 0.0065 0.009
Echinococcus multilocularis cathepsin L 0.0041 0.0137 0.0385

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 203 nM Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry ChEMBL. 21185183
Ki (binding) = 1140 nM Displacement of [3H]nisoxetine from human NET by scintillation proximity assay ChEMBL. 21185183
Ki (binding) > 4620 nM Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assay ChEMBL. 21185183
Ki (binding) > 6130 nM Displacement of [3H]citalopram from human SERT by scintillation proximity assay ChEMBL. 21185183

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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