Detailed information for compound 1462629

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 281.695 | Formula: C12H12ClN3O3
  • H donors: 4 H acceptors: 3 LogP: 0.94 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCN/C=c/1\c(=O)[nH]c2c([nH]c1=O)cc(cc2)Cl
  • InChi: 1S/C12H12ClN3O3/c13-7-1-2-9-10(5-7)16-12(19)8(11(18)15-9)6-14-3-4-17/h1-2,5-6,14,17H,3-4H2,(H,15,18)(H,16,19)/b8-6+
  • InChiKey: YWFXIUIBHZLOIZ-SOFGYWHQSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Brugia malayi Papain family cysteine protease containing protein 0.0529 0.2614 0.2607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0224 0.1063 0.1063
Leishmania major META domain containing protein 0.0221 0.1043 0.1843
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.1043 0.1843
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0322 0.1561 0.2765
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0976 0.4888 0.4888
Echinococcus granulosus calpain 5 0.0601 0.2976 0.2976
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0976 0.4888 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0026 0.0026
Echinococcus multilocularis Mastin 0.0028 0.0063 0.0063
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0092 0.0083
Schistosoma mansoni peptidylglycine monooxygenase 0.0125 0.0558 0.0558
Brugia malayi hypothetical protein 0.0021 0.003 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0092 0.0083
Echinococcus granulosus cathepsin l cysteine peptidase 0.0976 0.4888 0.4888
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0068 0.0068
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0224 0.1063 0.1063
Trypanosoma brucei protein I/6 0.0074 0.0298 0.0516
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.088 0.4399 0.7817
Trypanosoma brucei unspecified product 0.0021 0.0026 0.0032
Onchocerca volvulus Matrix metalloproteinase homolog 0.0052 0.0187 0.0323
Schistosoma mansoni amine GPCR 0.0021 0.003 0.003
Brugia malayi G protein-coupled receptor F59B2.13 0.0021 0.003 0.0022
Giardia lamblia Cathepsin B precursor 0.0224 0.1063 0.2728
Echinococcus granulosus neuropeptide receptor 0.0021 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0021 0.003 0.003
Plasmodium falciparum serine repeat antigen 3 0.0224 0.1063 0.2161
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.003 0.003
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0092 0.0148
Loa Loa (eye worm) hypothetical protein 0.0976 0.4888 0.4888
Trichomonas vaginalis centrin, putative 0.0074 0.0298 0.0594
Schistosoma mansoni histamine h1 receptor 0.0021 0.003 0.003
Brugia malayi putative neuropeptide receptor NPR1 0.0021 0.003 0.0022
Brugia malayi intermediate filament protein 0.0029 0.0068 0.006
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0224 0.1063 0.2133
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0764 0.381 0.6769
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0292 0.1405 0.2861
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.003 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4888 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0026 0.0037
Treponema pallidum NADH oxidase 0.0034 0.0092 0.5
Schistosoma mansoni neuronal calcium sensor 0.0074 0.0298 0.0298
Leishmania major DNA polymerase eta, putative 0.0048 0.0165 0.0279
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Leishmania major small myristoylated protein 4, putative 0.06 0.2972 0.5277
Loa Loa (eye worm) hypothetical protein 0.0057 0.0212 0.0212
Leishmania major cathepsin L-like protease 0.0976 0.4888 0.8688
Trypanosoma brucei Calpain-like protein CALP1.3 0.0512 0.2527 0.4484
Loa Loa (eye worm) hypothetical protein 0.003 0.0076 0.0076
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0529 0.2614 0.2607
Echinococcus multilocularis programmed cell death protein 0.0083 0.0342 0.0342
Echinococcus multilocularis cathepsin L cysteine protease 0.0976 0.4888 0.4888
Loa Loa (eye worm) hypothetical protein 0.0224 0.1063 0.1063
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.003 0.003
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0224 0.1063 0.2728
Schistosoma mansoni cathepsin C 0.0224 0.1063 0.1063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Schistosoma mansoni hypothetical protein 0.003 0.0076 0.0076
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0582 0.2882 0.2876
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0063 0.0063
Toxoplasma gondii ABC1 family protein 0.0039 0.0117 0.0223
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0046 0.0038
Giardia lamblia Cathepsin B precursor 0.0224 0.1063 0.2728
Echinococcus granulosus cathepsin b 0.1981 1 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0021 0.003 0.003
Echinococcus granulosus dna polymerase kappa 0.0021 0.0026 0.0026
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0233 0.0233
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.003 0.003
Schistosoma mansoni cathepsin F (C01 family) 0.0672 0.3337 0.3337
Toxoplasma gondii cathepsin B 0.0768 0.3827 0.7826
Toxoplasma gondii EF hand domain-containing protein 0.0074 0.0298 0.0594
Echinococcus multilocularis neuropeptide receptor 0.0021 0.003 0.003
Entamoeba histolytica cysteine proteinase 1, putative 0.0529 0.2614 0.5322
Echinococcus granulosus alpha 1A adrenergic receptor 0.0021 0.003 0.003
Trypanosoma cruzi major cysteine proteinase, putative 0.0369 0.18 0.1793
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0601 0.2976 0.297
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Loa Loa (eye worm) calpain family protein 1 0.0924 0.4621 0.4621
Brugia malayi calpain 5 0.0292 0.1405 0.1397
Trypanosoma brucei DNA polymerase eta, putative 0.0048 0.0165 0.0279
Giardia lamblia Hypothetical protein 0.0224 0.1063 0.2728
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0224 0.1063 0.2161
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0064 0.0244 0.0236
Echinococcus multilocularis fmrfamide receptor 0.0021 0.003 0.003
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Trypanosoma cruzi I/6 autoantigen, putative 0.0074 0.0298 0.029
Trypanosoma cruzi DNA polymerase eta, putative 0.0048 0.0165 0.0157
Echinococcus granulosus calbindin 32 0.0076 0.031 0.031
Onchocerca volvulus 0.0976 0.4888 1
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0224 0.1063 0.2161
Schistosoma mansoni hypothetical protein 0.0021 0.003 0.003
Brugia malayi cathepsin Z-like cysteine proteinase 0.0224 0.1063 0.1056
Trypanosoma cruzi conserved protein 0.0522 0.2575 0.2569
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0512 0.2527 0.2521
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0092 0.0092
Plasmodium vivax vivapain-1 0.0529 0.2614 0.5339
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0666 0.3307 0.3301
Schistosoma mansoni neuropeptide receptor 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Onchocerca volvulus 0.0976 0.4888 1
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0224 0.1063 0.2161
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0028 0.0063 0.0063
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0645 0.0645
Leishmania major hypothetical protein, conserved 0.0023 0.0038 0.0053
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1981 1 1
Toxoplasma gondii hypothetical protein 0.0292 0.1405 0.2861
Brugia malayi hypothetical protein 0.0028 0.0063 0.0054
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0224 0.1063 0.1063
Plasmodium vivax SET domain protein, putative 0.0064 0.0245 0.0484
Loa Loa (eye worm) cysteine protease 0.0976 0.4888 0.4888
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0224 0.1063 0.2161
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0074 0.0298 0.0516
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0092 0.0171
Echinococcus multilocularis sex peptide receptor 0.0021 0.003 0.003
Plasmodium falciparum thioredoxin reductase 0.0097 0.0413 0.083
Mycobacterium tuberculosis Conserved protein 0.0039 0.0117 0.0793
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0076 0.0138
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4888 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0512 0.2527 0.2521
Schistosoma mansoni lamin 0.0029 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0039 0.0117 0.0117
Echinococcus multilocularis neurocalcin 0.0074 0.0298 0.0298
Trypanosoma cruzi calmodulin, putative 0.0074 0.0298 0.029
Echinococcus granulosus g protein coupled receptor 0.0021 0.003 0.003
Brugia malayi Matrixin family protein 0.0024 0.0041 0.0033
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0249 0.0452
Onchocerca volvulus Chorion peroxidase homolog 0.0065 0.0249 0.0452
Loa Loa (eye worm) hypothetical protein 0.0023 0.0038 0.0038
Schistosoma mansoni peroxidasin 0.0065 0.0249 0.0249
Brugia malayi calcium-binding protein 0.0074 0.0298 0.029
Giardia lamblia Cysteine protease 0.0224 0.1063 0.2728
Trichomonas vaginalis calcium binding proteins, putative 0.0074 0.0298 0.0594
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0221 0.1043 0.1843
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0245 0.0245
Onchocerca volvulus 0.0065 0.0249 0.0452
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0245 0.0245
Mycobacterium tuberculosis Probable dehydrogenase 0.0221 0.1044 0.8868
Loa Loa (eye worm) TYRA-2 protein 0.0021 0.003 0.003
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0026 0.0026
Brugia malayi Cathepsin L-like precursor 0.0976 0.4888 0.4884
Toxoplasma gondii centrin, putative 0.0074 0.0298 0.0594
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0023 0.0038 0.0062
Echinococcus granulosus Mastin 0.0028 0.0063 0.0063
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.003 0.003
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.088 0.4399 0.7817
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0074 0.0298 0.0298
Echinococcus multilocularis serotonin receptor 0.0021 0.003 0.003
Onchocerca volvulus Cathepsin F homolog 0.0976 0.4888 1
Trichomonas vaginalis calcineurin B subunit, putative 0.0074 0.0298 0.0594
Giardia lamblia Cathepsin L-like protease 0.0224 0.1063 0.2728
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.003 0.003
Brugia malayi Peroxidasin 0.0065 0.0249 0.0241
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0117 0.0117
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0092 0.0171
Giardia lamblia Cathepsin B precursor 0.0224 0.1063 0.2728
Echinococcus multilocularis neuronal calcium sensor 0.0074 0.0298 0.0298
Brugia malayi Papain family cysteine protease containing protein 0.0224 0.1063 0.1056
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0021 0.003 0.003
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0236 0.1121 0.1121
Entamoeba histolytica cysteine proteinase, putative 0.0976 0.4888 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.003 0.003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0063 0.0063
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0028 0.0063 0.0063
Loa Loa (eye worm) melatonin receptor type 1A 0.0021 0.003 0.003
Brugia malayi neuropeptide F receptor 0.0021 0.003 0.0022
Echinococcus granulosus hypothetical protein 0.0021 0.003 0.003
Echinococcus granulosus caspase 2 0.0057 0.0212 0.0212
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.003 0.003
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0021 0.003 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Entamoeba histolytica calcium-binding protein, putative 0.0074 0.0298 0.056
Brugia malayi hypothetical protein 0.0021 0.003 0.0022
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.003 0.003
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0224 0.1063 0.2161
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0117 0.0793
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0086 0.0357 0.0357
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0252 0.0252
Trichomonas vaginalis esterase, putative 0.0039 0.0117 0.0223
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0117 0.0793
Brugia malayi ImpB/MucB/SamB family protein 0.0048 0.0165 0.0157
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0021 0.003 0.003
Echinococcus granulosus calumenin 0.0076 0.031 0.031
Echinococcus granulosus calmodulin 0.0074 0.0298 0.0298
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0074 0.0298 0.0298
Echinococcus multilocularis dna polymerase eta 0.0048 0.0165 0.0165
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.003 0.003
Onchocerca volvulus Cell death protein 3 homolog 0.0057 0.0212 0.0374
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0224 0.1063 0.1063
Schistosoma mansoni centrin 0.0074 0.0298 0.0298
Schistosoma mansoni opsin-like receptor 0.0021 0.003 0.003
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0117 0.0793
Entamoeba histolytica cysteine protease, putative 0.0976 0.4888 1
Plasmodium falciparum serine repeat antigen 2 0.0224 0.1063 0.2161
Leishmania major cathepsin L-like protease 0.0976 0.4888 0.8688
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0074 0.0298 0.0594
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.1344 0.2377
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Brugia malayi calpain family protein 1 0.1233 0.6193 0.619
Brugia malayi beta-lactamase family protein 0.0039 0.0117 0.0109
Entamoeba histolytica cysteine protease, putative 0.0224 0.1063 0.2133
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0026 0.0032
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0224 0.1063 0.2161
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0142 0.0645 0.0645
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.003 0.003
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0236 0.1121 0.1121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0224 0.1063 0.2161
Loa Loa (eye worm) hypothetical protein 0.0224 0.1063 0.1063
Onchocerca volvulus 0.0033 0.0091 0.0126
Echinococcus granulosus G protein coupled receptor 139 0.0021 0.003 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Echinococcus multilocularis calpain 7 (C02 family) 0.0601 0.2976 0.2976
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0037 0.0059
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0224 0.1063 0.1056
Echinococcus granulosus caspase 8 0.0017 0.0008 0.0008
Loa Loa (eye worm) EF hand family protein 0.0074 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.1121 0.5625 0.5621
Loa Loa (eye worm) hypothetical protein 0.0242 0.1153 0.1153
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.028 0.1344 0.2377
Entamoeba histolytica protein kinase, putative 0.0309 0.1493 0.3016
Echinococcus granulosus neuropeptide FF receptor 2 0.0021 0.003 0.003
Echinococcus granulosus fmrfamide receptor 0.0021 0.003 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0631 0.3133 0.3127
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0092 0.0083
Schistosoma mansoni reticulocalbin 0.0076 0.031 0.031
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0092 0.5
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0298 0.0516
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.1043 0.1843
Plasmodium vivax unspecified product 0.0305 0.1472 0.2999
Brugia malayi GnHR receptor homolog 0.0021 0.003 0.0022
Echinococcus granulosus 7TM GPCR rhodopsin 0.0021 0.003 0.003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0768 0.3827 0.3822
Loa Loa (eye worm) hypothetical protein 0.0941 0.4709 0.4709
Schistosoma mansoni neuropeptide receptor 0.0021 0.003 0.003
Echinococcus granulosus calpain A 0.0601 0.2976 0.2976
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.003 0.003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0221 0.1044 0.8863
Echinococcus granulosus sex peptide receptor 0.0021 0.003 0.003
Schistosoma mansoni cathepsin F (C01 family) 0.0976 0.4888 0.4888
Plasmodium falciparum thioredoxin reductase 0.0034 0.0092 0.0171
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0224 0.1063 0.2161
Onchocerca volvulus 0.0065 0.0249 0.0452
Plasmodium falciparum serine repeat antigen 9 0.0224 0.1063 0.2161
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.1043 0.1036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4888 1
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0058 0.0102
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.1344 0.2377
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0224 0.1063 0.2161
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0074 0.0298 0.0594
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0063
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1307 0.657 0.657
Echinococcus granulosus intermediate filament protein 0.0029 0.0068 0.0068
Trypanosoma cruzi centrin, putative 0.0083 0.0342 0.0334
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0021 0.003 0.003
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0092 0.0171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.003 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0092 0.7197
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Plasmodium vivax prefoldin subunit 6, putative 0.003 0.0076 0.0138
Leishmania major calcineurin B subunit, putative 0.0074 0.0298 0.0516
Onchocerca volvulus 0.0028 0.0063 0.0067
Echinococcus multilocularis calbindin 32 0.0076 0.031 0.031
Loa Loa (eye worm) calpain D 0.0292 0.1405 0.1405
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Echinococcus multilocularis transmembrane protease serine 3 0.0028 0.0063 0.0063
Echinococcus multilocularis calpain A 0.1309 0.6582 0.6582
Loa Loa (eye worm) transcription factor SMAD2 0.0132 0.0592 0.0592
Brugia malayi EF hand family protein 0.0074 0.0298 0.029
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Trypanosoma brucei prefoldin subunit, putative 0.003 0.0076 0.012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0529 0.2614 0.4639
Echinococcus multilocularis thyroid hormone receptor alpha 0.0146 0.0662 0.0662
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0245 0.117 1
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0086 0.0357 0.0357
Echinococcus granulosus EF hand domain containing family member A2 0.0074 0.0298 0.0298
Leishmania major hypothetical protein, unknown function 0.0292 0.1405 0.2486
Loa Loa (eye worm) hypothetical protein 0.0027 0.0058 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4888 1
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0252 0.0252
Trichomonas vaginalis calmodulin, putative 0.0074 0.0298 0.0594
Brugia malayi Matrixin family protein 0.0024 0.0041 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.003 0.003
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0816 0.4074 0.4069
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0976 0.4888 1
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0117 0.0223
Echinococcus granulosus dro:myosuppressin receptor 0.0021 0.003 0.003
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0224 0.1063 0.2728
Leishmania major hypothetical protein, conserved 0.0221 0.1043 0.1843
Schistosoma mansoni hypothetical protein 0.0074 0.0298 0.0298
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0021 0.003 0.003
Leishmania major prefoldin subunit, putative 0.003 0.0076 0.012
Schistosoma mansoni neuropeptide f receptor 76f 0.0021 0.003 0.003
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0224 0.1063 0.1063
Leishmania major receptor-type adenylate cyclase a-like protein 0.0221 0.1043 0.1843
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0802 0.4002 0.3997
Trypanosoma brucei Calpain-like protein 2 0.0647 0.321 0.5701
Giardia lamblia Cathepsin L-like protease 0.0224 0.1063 0.2728
Schistosoma mansoni calmodulin related calcium binding protein 0.0074 0.0298 0.0298
Echinococcus granulosus EF HAND 1 calcium binding site 0.0074 0.0298 0.0298
Brugia malayi cathepsin F-like cysteine proteinase 0.0224 0.1063 0.1056
Brugia malayi Cathepsin L-like precursor 0.0976 0.4888 0.4884
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0249 0.0249
Echinococcus multilocularis geminin 0.0181 0.0844 0.0844
Trypanosoma cruzi DNA polymerase eta, putative 0.0034 0.0092 0.0084
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0026 0.0037
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0041
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Schistosoma mansoni rab 0.0074 0.0298 0.0298
Echinococcus granulosus neuropeptide receptor A26 0.0021 0.003 0.003
Echinococcus granulosus transmembrane protease serine 3 0.0028 0.0063 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.003 0.003
Brugia malayi Matrixin family protein 0.0024 0.0041 0.0033
Plasmodium falciparum serine repeat antigen 1 0.0224 0.1063 0.2161
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0645 0.0645
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1981 1 1
Echinococcus multilocularis neuropeptide receptor 0.0021 0.003 0.003
Brugia malayi Serotonin receptor 0.0021 0.003 0.0022
Echinococcus multilocularis EF hand domain containing family member A2 0.0074 0.0298 0.0298
Mycobacterium tuberculosis Probable reductase 0.0221 0.1044 0.8868
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0021 0.003 0.003
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0224 0.1063 0.2161
Trichomonas vaginalis calmodulin, putative 0.0074 0.0298 0.0594
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0092 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.003 0.003
Brugia malayi Trypsin family protein 0.0028 0.0063 0.0054
Trichomonas vaginalis set domain proteins, putative 0.0505 0.249 0.5086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0672 0.3337 0.6822
Echinococcus granulosus geminin 0.0181 0.0844 0.0844
Trichomonas vaginalis calpain, putative 0.0292 0.1405 0.2861
Brugia malayi hypothetical protein 0.0027 0.0058 0.005
Entamoeba histolytica grainin, putative 0.0076 0.031 0.0583
Echinococcus multilocularis g protein coupled receptor 0.0021 0.003 0.003
Toxoplasma gondii kringle domain-containing protein 0.0023 0.0038 0.0062
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0631 0.3133 0.3127
Trypanosoma brucei I/6 autoantigen 0.0074 0.0298 0.0516
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0252 0.0252
Echinococcus multilocularis apoptotic protease activating factor 1 0.004 0.0124 0.0124
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Plasmodium falciparum serine repeat antigen 4 0.0224 0.1063 0.2161
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0092 0.5
Schistosoma mansoni myosin xvIII 0.0021 0.003 0.003
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0135 0.0607 0.0607
Echinococcus multilocularis neuropeptide s receptor 0.0021 0.003 0.003
Toxoplasma gondii cathepsin CPC2 0.0224 0.1063 0.2161
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0092 0.5
Schistosoma mansoni intermediate filament proteins 0.0029 0.0068 0.0068
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0026 0.0026
Brugia malayi Trypsin family protein 0.0028 0.0063 0.0054
Mycobacterium tuberculosis Conserved protein 0.0039 0.0117 0.0793
Leishmania major hypothetical protein, conserved 0.0221 0.1043 0.1843
Brugia malayi Papain family cysteine protease containing protein 0.0976 0.4888 0.4884
Echinococcus granulosus thioredoxin glutathione reductase 0.0097 0.0413 0.0413
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0029 0.0067 0.0357
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0117 0.0223
Schistosoma mansoni amine GPCR 0.0021 0.003 0.003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0874 0.4365 0.7757
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0224 0.1063 0.2161
Onchocerca volvulus 0.0976 0.4888 1
Leishmania major hypothetical protein, conserved 0.0074 0.0298 0.0516
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0063
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0074 0.0298 0.0594
Plasmodium falciparum serine repeat antigen 6 0.0224 0.1063 0.2161
Onchocerca volvulus Dual oxidase homolog 0.0065 0.0249 0.0452
Loa Loa (eye worm) thioredoxin reductase 0.0097 0.0413 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0529 0.2614 0.5339
Schistosoma mansoni calpain-7 (C02 family) 0.0601 0.2976 0.2976
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0021 0.003 0.003
Brugia malayi sulfakinin receptor protein 0.0021 0.003 0.0022
Giardia lamblia Hypothetical protein 0.0076 0.031 0.0746
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0224 0.1063 0.2728
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0224 0.1063 0.1063
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0224 0.1063 0.2161
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0221 0.1043 0.1843
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0046 0.0038
Brugia malayi hypothetical protein 0.013 0.0584 0.0576
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.003 0.003
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0252 0.0252
Trypanosoma brucei calpain, putative 0.0571 0.2827 0.5019
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0092 0.0148
Onchocerca volvulus 0.0672 0.3337 0.6808
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Schistosoma mansoni opsin-like receptor 0.0021 0.003 0.003
Schistosoma mansoni caspase-7 (C14 family) 0.0057 0.0212 0.0212
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0026 0.0018
Giardia lamblia Cathepsin B precursor 0.0224 0.1063 0.2728
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0063 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0529 0.2614 0.4639
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0017 0.0008 0.0008
Echinococcus granulosus neuronal calcium sensor 0.0074 0.0298 0.0298
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.1739 0.3547
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0142 0.0645 0.0645
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0221 0.1043 0.1843
Echinococcus granulosus g protein coupled receptor 0.0021 0.003 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0601 0.2976 0.297
Leishmania major hypothetical protein, conserved 0.0027 0.0058 0.0089
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0058 0.0102
Echinococcus multilocularis G-protein coupled receptor, putative 0.0021 0.003 0.003
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0021 0.003 0.003
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0632 0.3138 0.3138
Entamoeba histolytica cysteine proteinase, putative 0.0672 0.3337 0.6811
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0601 0.2976 0.297
Brugia malayi hypothetical protein 0.0021 0.003 0.0022
Schistosoma mansoni growth hormone secretagogue receptor 0.0021 0.003 0.003
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0249 0.0241
Schistosoma mansoni hypothetical protein 0.0028 0.0063 0.0063
Echinococcus granulosus somatostatin receptor 0.0021 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0298 0.0594
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0068 0.006
Loa Loa (eye worm) hypothetical protein 0.0292 0.1405 0.1405
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0292 0.1405 0.2861
Trypanosoma cruzi cysteine peptidase, putative 0.1121 0.5625 0.5621
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0896 0.448 0.448
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.1561 0.1554
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.003 0.003
Loa Loa (eye worm) RecQ helicase 0.0023 0.0037 0.0037
Leishmania major small myristoylated protein-1 0.0381 0.1857 0.3292
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Brugia malayi hypothetical protein 0.0021 0.003 0.0022
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.003 0.003
Plasmodium falciparum calpain 0.0292 0.1405 0.2861
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Onchocerca volvulus Cathepsin L homolog 0.0976 0.4888 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.003 0.003
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0092 0.0171
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0092 0.0172
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0062 0.0235 0.0227
Echinococcus granulosus tissue type plasminogen activator 0.0023 0.0038 0.0038
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0768 0.3827 0.3827
Brugia malayi larval opioid receptor 0.0021 0.003 0.0022
Leishmania major programmed cell death 6 protein-like protein 0.0074 0.0298 0.0516
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Plasmodium falciparum prefoldin subunit 6, putative 0.003 0.0076 0.0138
Trypanosoma brucei antigen, putative 0.0601 0.2976 0.5284
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0827 0.4131 0.7339
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0117 0.0793
Schistosoma mansoni neuropeptide receptor 0.0021 0.003 0.003
Brugia malayi Cathepsin L-like precursor 0.0305 0.1472 0.1465
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0092 0.0171
Onchocerca volvulus 0.0028 0.0063 0.0067
Toxoplasma gondii prefoldin subunit 6, putative 0.003 0.0076 0.0138
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0221 0.1043 0.1036
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0021 0.003 0.0022
Loa Loa (eye worm) matrix metalloproteinase 0.0024 0.0041 0.0041
Leishmania major DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Echinococcus multilocularis cysteine protease 0.0976 0.4888 0.4888
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0827 0.4131 0.7339
Schistosoma mansoni lamin 0.0029 0.0068 0.0068
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0092 0.0571
Brugia malayi Protein kinase domain containing protein 0.0023 0.0038 0.003
Leishmania major DNA polymerase eta, putative 0.0034 0.0092 0.015
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0058 0.005
Entamoeba histolytica cysteine protease, putative 0.0224 0.1063 0.2133
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0021 0.003 0.003
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0028 0.0063 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0224 0.1063 0.2161
Brugia malayi cathepsin F-like cysteine proteinase 0.0305 0.1472 0.1465
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.003 0.003
Loa Loa (eye worm) cathepsin B 0.0768 0.3827 0.3827
Loa Loa (eye worm) hypothetical protein 0.1981 1 1
Schistosoma mansoni hypothetical protein 0.0135 0.0607 0.0607
Toxoplasma gondii centrin 0.0074 0.0298 0.0594
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.003 0.003
Brugia malayi Trypsin family protein 0.0028 0.0063 0.0054
Echinococcus multilocularis g protein coupled receptor 0.0021 0.003 0.003
Echinococcus granulosus cathepsin L 0.0224 0.1063 0.1063
Trypanosoma brucei calpain-like protein, putative 0.0601 0.2976 0.5284
Brugia malayi hypothetical protein 0.0021 0.003 0.0022
Entamoeba histolytica calpain large subunit domain III containing protein 0.0309 0.1493 0.3016
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0021 0.003 0.003
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0092 0.0148
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.003 0.003
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0092 0.0171
Leishmania major cathepsin L-like protease 0.0976 0.4888 0.8688
Loa Loa (eye worm) hypothetical protein 0.004 0.0124 0.0124
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0529 0.2614 0.2614
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0117 0.0117
Onchocerca volvulus 0.0028 0.0063 0.0067
Leishmania major cysteine peptidase A (CPA) 0.0976 0.4888 0.8688
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0039 0.0117 0.0117
Onchocerca volvulus 0.0505 0.2491 0.5065
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0063 0.0063
Mycobacterium ulcerans hypothetical protein 0.0028 0.0063 0.3995
Toxoplasma gondii preprocathepsin c precursor, putative 0.0224 0.1063 0.2161
Plasmodium falciparum cysteine repeat modular protein 1 0.0023 0.0038 0.0062
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0874 0.4365 0.4361
Onchocerca volvulus 0.0028 0.0063 0.0067
Onchocerca volvulus 0.0976 0.4888 1
Trypanosoma cruzi centrin-3 0.0083 0.0342 0.0334
Trypanosoma brucei calmodulin, putative 0.0074 0.0298 0.0516
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0224 0.1063 0.1063
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0018
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.1561 0.1554
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0076 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Echinococcus multilocularis neuropeptide FF receptor 2 0.0021 0.003 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0224 0.1063 0.2161
Entamoeba histolytica calcium binding family protein 0.0074 0.0298 0.056
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Echinococcus multilocularis neuropeptide receptor A26 0.0021 0.003 0.003
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0292 0.1405 0.2861
Loa Loa (eye worm) beta-lactamase 0.0039 0.0117 0.0117
Echinococcus multilocularis caspase 2 0.0057 0.0212 0.0212
Echinococcus granulosus peptide allatostatin:somatostatin 0.0021 0.003 0.003
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0292 0.1405 0.2861
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0063
Brugia malayi hypothetical protein 0.0021 0.003 0.0022
Onchocerca volvulus 0.0029 0.0068 0.0078
Brugia malayi beta-lactamase 0.0039 0.0117 0.0109
Echinococcus multilocularis hypothetical protein 0.0601 0.2976 0.2976
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0221 0.1044 0.8868
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0601 0.2976 0.297
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0224 0.1063 0.1063
Loa Loa (eye worm) hypothetical protein 0.0029 0.0068 0.0068
Trypanosoma cruzi kinesin, putative 0.0309 0.1493 0.1485
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0117 1
Entamoeba histolytica cysteine proteinase, putative 0.0529 0.2614 0.5322
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0021 0.003 0.003
Brugia malayi Melatonin receptor type 1A 0.0021 0.003 0.0022
Echinococcus multilocularis musashi 0.0029 0.0068 0.0068
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0236 0.1121 0.1121
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0224 0.1063 0.2161
Brugia malayi hypothetical protein 0.004 0.0124 0.0116
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0322 0.0322
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0092 0.0083
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0117 0.0117
Plasmodium vivax vivapain-2 0.0976 0.4888 1
Brugia malayi Papain family cysteine protease containing protein 0.0529 0.2614 0.2607
Echinococcus granulosus orexin receptor type 2 0.0021 0.003 0.003
Schistosoma mansoni caspase-7 (C14 family) 0.0017 0.0008 0.0008
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0026 0.0026
Schistosoma mansoni cathepsin S (C01 family) 0.0224 0.1063 0.1063
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.003 0.003
Brugia malayi hypothetical protein 0.0017 0.001 0.0001
Echinococcus multilocularis calcium uptake protein 1 0.0076 0.031 0.031
Echinococcus granulosus cathepsin L 0.0529 0.2614 0.2614
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Onchocerca volvulus Peroxidase homolog 0.0065 0.0249 0.0452
Brugia malayi Pre-SET motif family protein 0.0064 0.0245 0.0237
Echinococcus granulosus cathepsin L cysteine protease 0.0529 0.2614 0.2614
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0252 0.0252
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0037 0.0059
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0021 0.003 0.003
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0026 0.0026
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0512 0.2527 0.2521
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0063
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.003 0.003
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0076 0.031 0.0302
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.0245 0.0245
Brugia malayi Dopamine receptor protein 2 0.0021 0.003 0.0022
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0117 0.0223
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0058 0.005
Giardia lamblia Hypothetical protein 0.003 0.0076 0.0131
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0021 0.003 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0038 0.003
Giardia lamblia Cathepsin L precursor 0.0224 0.1063 0.2728
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0874 0.4365 0.7757
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0074 0.0298 0.0516
Trypanosoma brucei hypothetical protein, conserved 0.0357 0.1739 0.3082
Entamoeba histolytica cysteine proteinase 2 0.0529 0.2614 0.5322
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0117 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Onchocerca volvulus 0.0039 0.0117 0.0179
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0493 0.243 0.2424
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0058 0.0102
Trypanosoma brucei centrin, putative 0.0074 0.0298 0.0516
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0135 0.0607 0.0607
Trichomonas vaginalis calmodulin, putative 0.0074 0.0298 0.0594
Echinococcus granulosus programmed cell death protein 0.0083 0.0342 0.0342
Brugia malayi Calmodulin-like protein 0.0074 0.0298 0.029
Schistosoma mansoni hypothetical protein 0.0021 0.003 0.003
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.1153 0.1153
Brugia malayi Cathepsin L-like precursor 0.0976 0.4888 0.4884
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0026 0.0032
Trypanosoma cruzi cysteine proteinase, putative 0.0529 0.2614 0.2607
Loa Loa (eye worm) hypothetical protein 0.0039 0.0117 0.0117
Brugia malayi cathepsin L-like cysteine proteinase 0.0224 0.1063 0.1056
Brugia malayi glutathione reductase 0.0097 0.0413 0.0405
Leishmania major kinesin, putative 0.0309 0.1493 0.2643
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0026 0.0032
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0976 0.4888 1
Leishmania major protein kinase, putative 0.0074 0.0298 0.0516
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1981 1 1
Loa Loa (eye worm) matrixin family protein 0.0052 0.0187 0.0187
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0021 0.003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0221 0.1044 0.8868
Echinococcus granulosus EF hand domain containing family member A2 0.0076 0.031 0.031
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0021 0.003 0.003
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0074 0.0298 0.0298
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0512 0.2527 0.2521
Onchocerca volvulus Matrilysin homolog 0.0024 0.0041 0.0022
Echinococcus granulosus g protein coupled receptor 0.0021 0.003 0.003
Trichomonas vaginalis calpain, putative 0.0292 0.1405 0.2861
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.003 0.003
Echinococcus granulosus apoptotic protease activating factor 1 0.004 0.0124 0.0124
Schistosoma mansoni caspase-3 (C14 family) 0.0017 0.0008 0.0008
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0117 0.0793
Onchocerca volvulus 0.0064 0.0245 0.0442
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0097 0.0413 0.3373
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.1174 1
Giardia lamblia Cathepsin L precursor 0.0224 0.1063 0.2728
Echinococcus granulosus calpain 0.0601 0.2976 0.2976
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Mycobacterium ulcerans hypothetical protein 0.0039 0.0117 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.003 0.003
Entamoeba histolytica calmodulin, putative 0.0074 0.0298 0.056
Brugia malayi MH2 domain containing protein 0.0132 0.0592 0.0584
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0092 0.0092
Trypanosoma cruzi cysteine proteinase, putative 0.0529 0.2614 0.2607
Plasmodium vivax centrin-1, putative 0.0074 0.0298 0.0594
Giardia lamblia Cathepsin B precursor 0.0768 0.3827 1
Leishmania major i/6 autoantigen-like protein 0.0074 0.0298 0.0516
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0092 0.0148
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0063 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.003 0.003
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.003 0.003
Giardia lamblia Cathepsin B precursor 0.0768 0.3827 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.003 0.003
Echinococcus granulosus neurocalcin 0.0074 0.0298 0.0298
Brugia malayi Papain family cysteine protease containing protein 0.0224 0.1063 0.1056
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.003 0.003
Leishmania major hypothetical protein, conserved 0.0221 0.1043 0.1843
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0292 0.1405 0.2486
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0444 0.2178 0.2178
Echinococcus multilocularis orexin receptor type 2 0.0021 0.003 0.003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0305 0.1472 0.1472
Echinococcus granulosus glycoprotein Antigen 5 0.0028 0.0063 0.0063
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.003 0.003
Schistosoma mansoni biogenic amine receptor 0.0021 0.003 0.003
Leishmania major calmodulin, putative 0.0074 0.0298 0.0516
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0236 0.1121 0.1113
Echinococcus granulosus bloom syndrome protein 0.0023 0.0037 0.0037
Brugia malayi calpain D 0.0292 0.1405 0.1397
Brugia malayi EF hand family protein 0.0076 0.031 0.0302
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0512 0.2527 0.4484
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0221 0.1043 0.1843
Entamoeba histolytica cysteine proteinase, putative 0.0976 0.4888 1
Leishmania major cathepsin L-like protease 0.0976 0.4888 0.8688
Onchocerca volvulus Matrilysin homolog 0.0052 0.0187 0.0323
Leishmania major calpain family cysteine protease-like protein 0.0512 0.2527 0.4484
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0092 0.0092
Brugia malayi Serotonin receptor 0.0021 0.003 0.0022
Loa Loa (eye worm) blistered cuticle protein 3 0.0065 0.0249 0.0249
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4888 1
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0117 0.0223
Trypanosoma brucei cysteine peptidase, putative 0.0512 0.2527 0.4484
Loa Loa (eye worm) calpain 5 0.0309 0.1493 0.1493
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Leishmania major calmodulin, putative 0.0074 0.0298 0.0516
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Plasmodium falciparum cysteine proteinase falcipain 1 0.0529 0.2614 0.5339
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0245 0.0484
Schistosoma mansoni cathepsin B (C01 family) 0.0224 0.1063 0.1063
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0092 0.0148
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0017 0.0008 0.0008
Echinococcus multilocularis thioredoxin glutathione reductase 0.0097 0.0413 0.0413
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0074 0.0298 0.029
Loa Loa (eye worm) hypothetical protein 0.0039 0.0117 0.0117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0142 0.0645 0.0645
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0601 0.2976 0.5284
Loa Loa (eye worm) hypothetical protein 0.0125 0.0558 0.0558
Trypanosoma brucei hypothetical protein 0.0571 0.2827 0.5019
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trichomonas vaginalis calmodulin, putative 0.0076 0.031 0.0617
Brugia malayi Papain family cysteine protease containing protein 0.0224 0.1063 0.1056
Schistosoma mansoni DNA polymerase eta 0.0048 0.0165 0.0165
Trichomonas vaginalis centrin, putative 0.0074 0.0298 0.0594
Trichomonas vaginalis calmodulin-2, putative 0.0074 0.0298 0.0594
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0292 0.1405 0.2861
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0224 0.1063 0.2161
Echinococcus granulosus neuropeptide s receptor 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0924 0.4621 0.4621
Schistosoma mansoni amine GPCR 0.0021 0.003 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0068 0.0068
Schistosoma mansoni biogenic amine receptor 0.0021 0.003 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0874 0.4365 0.4361
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0074 0.0298 0.029
Leishmania major centrin, putative 0.0074 0.0298 0.0516
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0224 0.1063 0.2161
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1307 0.657 0.657
Plasmodium falciparum serine repeat antigen 5 0.0224 0.1063 0.2161
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0493 0.243 0.4312
Schistosoma mansoni hypothetical protein 0.0028 0.0063 0.0063
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.003 0.003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.003 0.003
Leishmania major calmodulin-like protein 0.0074 0.0298 0.0516
Leishmania major calmodulin-like protein 0.0074 0.0298 0.0516
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0037 0.0029
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0512 0.2527 0.2521
Trypanosoma cruzi unspecified product 0.0381 0.1857 0.185
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.003 0.003
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0021 0.003 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.0976 0.4888 0.4884
Trypanosoma brucei calpain-like protein, putative 0.0601 0.2976 0.5284
Echinococcus multilocularis calmodulin 0.0074 0.0298 0.0298
Trypanosoma cruzi hypothetical protein, conserved 0.0357 0.1739 0.1732
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0827 0.4131 0.7339
Onchocerca volvulus 0.0074 0.0298 0.0552
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0305 0.1472 0.1465
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0058 0.0102
Entamoeba histolytica cysteine proteinase, putative 0.0529 0.2614 0.5322
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0305 0.1472 0.1472
Brugia malayi Trypsin-like protease protein 5 0.0028 0.0063 0.0054
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0322 0.0322
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0224 0.1063 0.2161
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1981 1 1
Loa Loa (eye worm) calpain 0.0601 0.2976 0.2976
Leishmania major trypanothione reductase 0.0097 0.0413 0.0721
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0074 0.0298 0.029
Loa Loa (eye worm) hypothetical protein 0.034 0.1649 0.1649
Trypanosoma cruzi calmodulin, putative 0.0074 0.0298 0.029
Onchocerca volvulus 0.0976 0.4888 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0908 0.454 0.454
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0292 0.1405 0.2861
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0117 0.0117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0092 0.0083
Brugia malayi Trypsin family protein 0.0028 0.0063 0.0054
Echinococcus multilocularis glycoprotein Antigen 5 0.0028 0.0063 0.0063
Echinococcus granulosus enteropeptidase 0.0028 0.0063 0.0063
Giardia lamblia Cysteine protease 0.0224 0.1063 0.2728
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4888 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0224 0.1063 0.1056
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0023 0.003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0874 0.4365 0.7757
Schistosoma mansoni calmodulin 0.0074 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Loa Loa (eye worm) hypothetical protein 0.0224 0.1063 0.1063
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0224 0.1063 0.1063
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0631 0.3133 0.5563
Schistosoma mansoni amine GPCR 0.0021 0.003 0.003
Leishmania major cathepsin L-like protease 0.1121 0.5625 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0224 0.1063 0.2161
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0041
Brugia malayi hypothetical protein 0.0021 0.003 0.0022
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0074 0.0298 0.0298
Schistosoma mansoni dopamine-beta-monooxygenase 0.0125 0.0558 0.0558
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0037 0.0037
Trypanosoma cruzi small myristoylated protein 1-1 0.0381 0.1857 0.185
Onchocerca volvulus 0.0632 0.3138 0.6397
Echinococcus granulosus g-protein coupled receptor 0.0021 0.003 0.003
Onchocerca volvulus 0.0029 0.0068 0.0078
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0666 0.3307 0.5873
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0221 0.1044 0.8868
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0672 0.3337 0.3337
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0221 0.1044 0.8868
Echinococcus multilocularis calumenin 0.0076 0.031 0.031
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0224 0.1063 0.1063
Trypanosoma cruzi cysteine protease, putative 0.0529 0.2614 0.2607
Loa Loa (eye worm) hypothetical protein 0.0039 0.0117 0.0117
Echinococcus granulosus cathepsin l1 0.0976 0.4888 0.4888
Trichomonas vaginalis calmodulin, putative 0.0074 0.0298 0.0594
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.088 0.4399 0.4394
Giardia lamblia Hypothetical protein 0.0224 0.1063 0.2728
Trypanosoma cruzi prefoldin subunit, putative 0.003 0.0076 0.0068
Loa Loa (eye worm) fibroinase 0.0976 0.4888 0.4888
Brugia malayi Cathepsin L-like precursor 0.0672 0.3337 0.3332
Echinococcus granulosus calpain A 0.1309 0.6582 0.6582
Giardia lamblia Encystation-specific protease 0.0224 0.1063 0.2728
Schistosoma mansoni hypothetical protein 0.0049 0.0172 0.0172
Entamoeba histolytica prefoldin subunit 6, putative 0.003 0.0076 0.0102
Mycobacterium tuberculosis Conserved protein 0.0039 0.0117 0.0793
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0249 0.0241
Brugia malayi Cathepsin L-like cysteine proteinase 0.0672 0.3337 0.3332
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0224 0.1063 0.1063
Brugia malayi Cathepsin L-like precursor 0.0672 0.3337 0.3332
Brugia malayi Cathepsin L-like precursor 0.0976 0.4888 0.4884
Echinococcus multilocularis fmrfamide receptor 0.0021 0.003 0.003
Schistosoma mansoni calpain (C02 family) 0.0601 0.2976 0.2976
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Echinococcus granulosus cathepsin b 0.1981 1 1
Schistosoma mansoni hypothetical protein 0.0055 0.0203 0.0203
Brugia malayi calpain 7 0.0601 0.2976 0.297
Echinococcus granulosus caspase 0.0017 0.0008 0.0008
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0249 0.0241
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1307 0.657 0.657
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.003 0.003
Giardia lamblia Cathepsin B precursor 0.0224 0.1063 0.2728
Trypanosoma cruzi small myristoylated protein 1-2 0.0381 0.1857 0.185
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4888 1
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.1043 0.1036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.003 0.003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.088 0.4399 0.4394
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0666 0.3307 0.3301
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.003 0.003
Echinococcus multilocularis G protein coupled receptor 139 0.0021 0.003 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.0529 0.2614 0.2607
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0092 0.0083
Trypanosoma cruzi prefoldin subunit, putative 0.003 0.0076 0.0068
Plasmodium vivax hypothetical protein, conserved 0.0076 0.031 0.0617
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0976 0.4888 0.4888
Trypanosoma cruzi centrin, putative 0.0083 0.0342 0.0334
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0571 0.2827 0.5019
Trypanosoma brucei centrin, putative 0.0074 0.0298 0.0516
Echinococcus granulosus tar DNA binding protein 0.0065 0.0252 0.0252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4888 1
Entamoeba histolytica cysteine protease, putative 0.0224 0.1063 0.2133
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0493 0.243 0.2424
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0092 0.0171
Echinococcus multilocularis calpain 5 0.0601 0.2976 0.2976
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.003 0.003
Brugia malayi programmed cell death protein 6 0.0074 0.0298 0.029
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0426 0.2088 0.2082
Plasmodium vivax calpain, putative 0.0601 0.2976 0.6082
Leishmania major hypothetical protein, conserved 0.0357 0.1739 0.3082
Brugia malayi follicle stimulating hormone receptor 0.0021 0.003 0.0022
Schistosoma mansoni neuronal calcium sensor 0.0074 0.0298 0.0298
Echinococcus multilocularis peroxidasin 0.0065 0.0249 0.0249
Brugia malayi Cell death protein 3 precursor 0.0057 0.0212 0.0203
Plasmodium falciparum glutathione reductase 0.0034 0.0092 0.0171
Trypanosoma brucei centrin-3 0.0083 0.0342 0.0595
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0117 0.0194
Plasmodium falciparum glutathione reductase 0.0097 0.0413 0.083
Echinococcus multilocularis cathepsin b 0.1981 1 1
Onchocerca volvulus 0.0065 0.0249 0.0452
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0224 0.1063 0.1063
Echinococcus granulosus 7tm_1 domain containing protein 0.0021 0.003 0.003
Schistosoma mansoni survival motor neuron protein 0.0049 0.0172 0.0172
Trypanosoma brucei calpain-like protein, putative 0.0601 0.2976 0.5284
Schistosoma mansoni thyroid hormone receptor 0.0146 0.0662 0.0662
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0063 0.0063
Trichomonas vaginalis calmodulin, putative 0.0074 0.0298 0.0594
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0908 0.454 0.454
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Leishmania major small myristoylated protein-3, putative 0.0322 0.1561 0.2765
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0224 0.1063 0.1063
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Schistosoma mansoni hypothetical protein 0.0181 0.0844 0.0844
Loa Loa (eye worm) hypothetical protein 0.0028 0.0065 0.0065
Echinococcus multilocularis g-protein coupled receptor 0.0021 0.003 0.003
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.028 0.1344 0.2377
Brugia malayi Blistered cuticle protein 3 0.0065 0.0249 0.0241
Echinococcus multilocularis caspase 8 0.0017 0.0008 0.0008
Loa Loa (eye worm) RNA binding protein 0.0065 0.0252 0.0252
Trypanosoma brucei trypanothione reductase 0.0097 0.0413 0.0721
Brugia malayi calpain 5 0.0309 0.1493 0.1485
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.003 0.003
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0224 0.1063 0.2161
Plasmodium vivax unspecified product 0.0529 0.2614 0.5339
Brugia malayi Dopamine receptor 0.0021 0.003 0.0022
Trichomonas vaginalis calcium binding protein, putative 0.0083 0.0342 0.0685
Echinococcus granulosus serotonin receptor 0.0021 0.003 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0117 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0976 0.4888 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.003 0.003
Brugia malayi RE15519p 0.0021 0.003 0.0022
Loa Loa (eye worm) hypothetical protein 0.0236 0.1121 0.1121
Loa Loa (eye worm) hypothetical protein 0.0029 0.0067 0.0067
Brugia malayi hypothetical protein 0.0065 0.0249 0.0241
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0224 0.1063 0.2133
Echinococcus multilocularis EF hand domain containing family member A2 0.0076 0.031 0.031
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0142 0.0645 0.0637
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.003 0.003
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1981 1 1
Onchocerca volvulus Peroxidasin homolog 0.0065 0.0249 0.0452
Entamoeba histolytica calpain family cysteine protease, putative 0.0292 0.1405 0.2835
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Onchocerca volvulus 0.0039 0.0117 0.0179
Echinococcus multilocularis calpain family protein 1, d 0.0924 0.4621 0.4621
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Plasmodium vivax glutathione reductase, putative 0.0097 0.0413 0.083
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0221 0.1043 0.1843
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0018
Schistosoma mansoni adenoreceptor 0.0021 0.003 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.1121 0.5625 0.5621
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0529 0.2614 0.2614
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0021 0.003 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0245 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0224 0.1063 0.2161
Echinococcus granulosus allatostatin A receptor 0.0021 0.003 0.003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0026 0.0018
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Echinococcus multilocularis lamin dm0 0.0029 0.0068 0.0068
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0125 0.0558 0.055
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0117 0.0454
Schistosoma mansoni ef hand domain family member A2 0.0074 0.0298 0.0298
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.06 0.2972 0.2966
Trichomonas vaginalis calmodulin, putative 0.0083 0.0342 0.0685
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0976 0.4888 1
Schistosoma mansoni hypothetical protein 0.0181 0.0844 0.0844
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0026 0.0032
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0292 0.1405 0.2861
Echinococcus granulosus lamin dm0 0.0029 0.0068 0.0068
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0322 0.1561 0.1554
Loa Loa (eye worm) hypothetical protein 0.0672 0.3337 0.3337
Brugia malayi TAR-binding protein 0.0065 0.0252 0.0244
Onchocerca volvulus 0.0028 0.0063 0.0067
Trypanosoma cruzi caltractin, putative 0.0074 0.0298 0.029
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0021 0.003 0.003
Plasmodium falciparum cysteine proteinase falcipain 3 0.0976 0.4888 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0224 0.1063 0.2161
Loa Loa (eye worm) TK/ROR protein kinase 0.0023 0.0038 0.0038
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0764 0.381 0.6769
Entamoeba histolytica cysteine protease, putative 0.0224 0.1063 0.2133
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0092 0.0171
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Echinococcus multilocularis cathepsin L cysteine protease 0.0976 0.4888 0.4888
Schistosoma mansoni hypothetical protein 0.0074 0.0298 0.0298
Leishmania major hypothetical protein, conserved 0.0221 0.1043 0.1843
Onchocerca volvulus 0.004 0.0124 0.0194
Giardia lamblia Cathepsin L precursor 0.0224 0.1063 0.2728
Mycobacterium ulcerans beta-lactamase 0.0039 0.0117 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Echinococcus multilocularis calpain 0.0601 0.2976 0.2976
Brugia malayi calpain family protein 1 0.1233 0.6193 0.619
Trypanosoma brucei cysteine peptidase C (CPC) 0.0768 0.3827 0.6799
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0224 0.1063 0.2728
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0249 0.0241
Echinococcus multilocularis prefoldin subunit 6 0.003 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0063
Toxoplasma gondii thioredoxin reductase 0.0097 0.0413 0.083
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0512 0.2527 0.4484
Trichomonas vaginalis myosin light chain 1, putative 0.0074 0.0298 0.0594
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.003 0.003
Schistosoma mansoni hypothetical protein 0.004 0.0124 0.0124
Entamoeba histolytica cysteine proteinase, putative 0.0529 0.2614 0.5322
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0117 0.0117
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0074 0.0298 0.029
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0117 0.0223
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Plasmodium vivax serine-repeat antigen (SERA) 0.0224 0.1063 0.2161
Toxoplasma gondii troponin c, isotype gamma, putative 0.0074 0.0298 0.0594
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Trypanosoma cruzi kinesin, putative 0.0309 0.1493 0.1485
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.028 0.1344 0.1336
Leishmania major cathepsin L-like protease 0.1121 0.5625 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.003 0.003
Plasmodium falciparum serine repeat antigen 7 0.0224 0.1063 0.2161
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.003 0.003
Echinococcus multilocularis cathepsin L 0.0224 0.1063 0.1063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0529 0.2614 0.5339
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Echinococcus multilocularis cysteine protease 0.0976 0.4888 0.4888
Schistosoma mansoni calpain-2 (C02 family) 0.0292 0.1405 0.1405
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0034 0.0092 0.0172
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0252 0.0244
Toxoplasma gondii EFHC1, putative 0.0074 0.0298 0.0594
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0013 0.0013
Echinococcus multilocularis g protein coupled receptor 0.0021 0.003 0.003
Trypanosoma brucei Calpain-like protein 1.2 0.0666 0.3307 0.5873
Trichomonas vaginalis conserved hypothetical protein 0.0224 0.1063 0.2161
Brugia malayi RNA binding protein 0.0065 0.0252 0.0244
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0117 0.0109
Echinococcus multilocularis cathepsin L 0.0529 0.2614 0.2614
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0224 0.1063 0.2161
Echinococcus granulosus cathepsin l1 0.0672 0.3337 0.3337
Echinococcus granulosus lamin 0.0029 0.0068 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0224 0.1063 0.2161
Trichomonas vaginalis calcium binding protein, putative 0.0074 0.0298 0.0594
Trypanosoma brucei small myristoylated protein 1-2 0.0381 0.1857 0.3292
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0074 0.0298 0.0298
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Toxoplasma gondii cathepsin CPC1 0.0224 0.1063 0.2161
Schistosoma mansoni hypothetical protein 0.0021 0.003 0.003
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0021 0.003 0.003
Trypanosoma cruzi I/6 autoantigen, putative 0.0074 0.0298 0.029
Echinococcus multilocularis serotonin receptor 0.0021 0.003 0.003
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0024 0.0041 0.0041
Trichomonas vaginalis calcineurin B subunit, putative 0.0076 0.031 0.0617
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.1043 0.1036
Leishmania major centrin, putative,caltractin, putative 0.0074 0.0298 0.0516
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Brugia malayi hypothetical protein 0.0021 0.003 0.0022
Echinococcus granulosus peroxidasin 0.0065 0.0249 0.0249
Echinococcus multilocularis cathepsin b 0.1981 1 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0021 0.003 0.0022
Trichomonas vaginalis calcium binding protein, putative 0.0074 0.0298 0.0594
Plasmodium vivax unspecified product 0.0224 0.1063 0.2161
Brugia malayi G protein-coupled receptor 0.0021 0.003 0.0022
Schistosoma mansoni cathepsin F (C01 family) 0.0976 0.4888 0.4888
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0074 0.0298 0.056
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.028 0.1344 0.2377
Schistosoma mansoni thyroid hormone receptor 0.0146 0.0662 0.0662
Loa Loa (eye worm) calmodulin-like protein 0.0074 0.0298 0.0298
Onchocerca volvulus 0.0039 0.0117 0.0179
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0092 0.0083
Leishmania major hypothetical protein, conserved 0.0076 0.031 0.0536
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0252 0.0252
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0245 0.117 0.996
Brugia malayi Cathepsin L-like precursor 0.0976 0.4888 0.4884
Leishmania major phospholipase c-like protein 0.0074 0.0298 0.0516
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0172 0.0164
Entamoeba histolytica calmodulin, putative 0.0074 0.0298 0.056
Schistosoma mansoni mitochondrial solute carrier 0.0074 0.0298 0.0298
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0768 0.3827 0.6799
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0092 0.0148
Echinococcus multilocularis dro:myosuppressin receptor 0.0021 0.003 0.003
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0221 0.1043 0.1036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0672 0.3337 0.6822
Entamoeba histolytica grainin 2 0.0083 0.0342 0.0651
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0645 0.0645
Brugia malayi cathepsin L precursor 0.0224 0.1063 0.1056
Loa Loa (eye worm) hypothetical protein 0.0224 0.1063 0.1063
Loa Loa (eye worm) hypothetical protein 0.1233 0.6193 0.6193
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0224 0.1063 0.2161
Onchocerca volvulus 0.0224 0.1063 0.2126
Onchocerca volvulus 0.0028 0.0063 0.0067
Trichomonas vaginalis calpain, putative 0.0292 0.1405 0.2861
Giardia lamblia Cathepsin L precursor 0.0224 0.1063 0.2728
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0117 0.0223
Onchocerca volvulus Cathepsin L homolog 0.0224 0.1063 0.2126
Brugia malayi G-protein coupled receptor 0.0021 0.003 0.0022
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1233 0.6193 0.6193
Loa Loa (eye worm) hypothetical protein 0.0064 0.0245 0.0245
Loa Loa (eye worm) calpain family protein 1 0.1233 0.6193 0.6193
Echinococcus granulosus centrin 2 0.0074 0.0298 0.0298
Leishmania major centrin, putative 0.0074 0.0298 0.0516
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0224 0.1063 0.2161
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0874 0.4365 0.7757
Loa Loa (eye worm) glutathione reductase 0.0097 0.0413 0.0413
Loa Loa (eye worm) hypothetical protein 0.0074 0.0298 0.0298
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0252 0.0252
Brugia malayi neuropeptide F receptor 0.0021 0.003 0.0022
Brugia malayi Matrixin family protein 0.0057 0.0211 0.0203
Trypanosoma brucei small myristoylated protein 1-1 0.0381 0.1857 0.3292
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma brucei kinesin, putative 0.0309 0.1493 0.2643
Trypanosoma brucei unspecified product 0.0221 0.1043 0.1843
Giardia lamblia Cathepsin L precursor 0.0224 0.1063 0.2728
Leishmania major hypothetical protein, conserved 0.0039 0.0117 0.0194
Schistosoma mansoni peroxidasin 0.0065 0.0249 0.0249
Echinococcus granulosus cathepsin L cysteine proteinase 0.0976 0.4888 0.4888
Trichomonas vaginalis calmodulin, putative 0.0074 0.0298 0.0594
Mycobacterium ulcerans lipase LipD 0.0039 0.0117 1
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0224 0.1063 0.2161
Mycobacterium ulcerans hydrolase 0.0029 0.0067 0.4505
Trypanosoma cruzi cruzipain precursor, putative 0.0305 0.1472 0.1465
Leishmania major hypothetical protein, conserved 0.0221 0.1043 0.1843
Schistosoma mansoni biogenic amine receptor 0.0021 0.003 0.003
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0021 0.003 0.003
Schistosoma mansoni hypothetical protein 0.0033 0.0091 0.0091
Trypanosoma brucei Calpain-like protein 1.1 0.0874 0.4365 0.7757
Trypanosoma brucei conserved protein 0.023 0.1091 0.1928
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0976 0.4888 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0647 0.321 0.5701
Giardia lamblia Cathepsin L precursor 0.0224 0.1063 0.2728
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0224 0.1063 0.2161
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0493 0.243 0.4312
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.003 0.003
Onchocerca volvulus Cathepsin L homolog 0.0976 0.4888 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.088 0.4399 0.7817
Leishmania major cathepsin L-like protease 0.1121 0.5625 1
Schistosoma mansoni reticulocalbin 0.0074 0.0298 0.0298
Echinococcus multilocularis programmed cell death protein 0.0083 0.0342 0.0342
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma cruzi calpain cysteine peptidase, putative 0.088 0.4399 0.4394
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Brugia malayi KE2 family protein 0.003 0.0076 0.0068
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0249 0.0249
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0292 0.1405 0.2861
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0493 0.243 0.4312
Giardia lamblia Cysteine protease 0.0224 0.1063 0.2728
Onchocerca volvulus 0.0023 0.0038 0.0017
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0029 0.0067 0.0059
Plasmodium falciparum serine repeat antigen 8 0.0224 0.1063 0.2161
Trypanosoma brucei Component of motile flagella 41 0.0074 0.0298 0.0516
Echinococcus multilocularis caspase 0.0017 0.0008 0.0008
Onchocerca volvulus 0.0024 0.0041 0.0022
Loa Loa (eye worm) animal heme peroxidase 0.0065 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0512 0.2527 0.4484
Entamoeba histolytica hypothetical protein, conserved 0.0076 0.031 0.0583
Schistosoma mansoni calpain C (C02 family) 0.0601 0.2976 0.2976
Schistosoma mansoni amine GPCR 0.0021 0.003 0.003
Plasmodium vivax serine-repeat antigen (SERA) 0.0224 0.1063 0.2161
Brugia malayi Animal haem peroxidase family protein 0.0065 0.0249 0.0241
Entamoeba histolytica cysteine protease, putative 0.0224 0.1063 0.2133
Onchocerca volvulus Peroxidase homolog 0.0065 0.0249 0.0452
Schistosoma mansoni opsin-like receptor 0.0021 0.003 0.003
Brugia malayi Hemopexin family protein 0.0033 0.0091 0.0083
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0529 0.2614 0.2614
Brugia malayi G-protein coupled receptor 0.0021 0.003 0.0022
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Plasmodium vivax vivapain-3 0.0529 0.2614 0.5339
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0224 0.1063 0.2161
Brugia malayi Kringle domain containing protein 0.0023 0.0038 0.003
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.003 0.003
Echinococcus granulosus calcium uptake protein 1 0.0076 0.031 0.031
Schistosoma mansoni cathepsin s 0.0305 0.1472 0.1472
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0074 0.0298 0.056
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0092 0.0148
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0092 0.7197
Entamoeba histolytica hypothetical protein 0.0224 0.1063 0.2133
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.003 0.003
Entamoeba histolytica cysteine protease, putative 0.0224 0.1063 0.2133
Toxoplasma gondii cathepsin CPL 0.0976 0.4888 1
Echinococcus multilocularis somatostatin receptor 0.0021 0.003 0.003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0028 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0224 0.1063 0.1063
Loa Loa (eye worm) hypothetical protein 0.0048 0.0165 0.0165
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0142 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0292 0.1405 0.2486
Onchocerca volvulus 0.0049 0.0172 0.0293
Trypanosoma cruzi calmodulin, putative 0.0074 0.0298 0.029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0245 0.0245
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0224 0.1063 0.2161
Trypanosoma brucei caltractin, putative 0.0083 0.0342 0.0595
Loa Loa (eye worm) programmed cell death protein 6 0.0076 0.031 0.031
Brugia malayi hypothetical protein 0.0242 0.1153 0.1146
Entamoeba histolytica cysteine proteinase, putative 0.0529 0.2614 0.5322
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.003 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0245 0.0245
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0221 0.1043 0.1036
Schistosoma mansoni hypothetical protein 0.0292 0.1405 0.1405
Giardia lamblia Cathepsin B precursor 0.0768 0.3827 1
Trypanosoma brucei calpain, putative 0.0292 0.1405 0.2486
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0976 0.4888 0.4888
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0802 0.4002 0.3997
Loa Loa (eye worm) matrixin family protein 0.0057 0.0211 0.0211
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0026 0.0032
Echinococcus granulosus cysteine protease 0.0529 0.2614 0.2614
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.003 0.003
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.1153 0.1153
Echinococcus multilocularis enteropeptidase 0.0028 0.0063 0.0063
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0028 0.0063 0.0063
Loa Loa (eye worm) ctsf protein 0.0976 0.4888 0.4888
Echinococcus multilocularis lamin 0.0029 0.0068 0.0068
Schistosoma mansoni calmodulin 0.0074 0.0298 0.0298
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0021 0.003 0.0022
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0512 0.2527 0.2521
Brugia malayi putative neuropeptide receptor 0.0021 0.003 0.0022
Schistosoma mansoni neuronal calcium sensor 0.0074 0.0298 0.0298
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0021 0.003 0.003
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1307 0.657 0.657
Trypanosoma cruzi hypothetical protein, conserved 0.0357 0.1739 0.1732
Giardia lamblia Cysteine protease 0.0224 0.1063 0.2728
Echinococcus multilocularis allatostatin A receptor 0.0021 0.003 0.003
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0117 0.0793
Leishmania major calpain protease-like protein 0.0292 0.1405 0.2486
Schistosoma mansoni neuronal calcium sensor 0.0074 0.0298 0.0298
Brugia malayi Dopamine receptor protein 1 0.0021 0.003 0.0022
Trypanosoma cruzi cruzipain precursor, putative 0.1121 0.5625 0.5621
Leishmania major hypothetical protein, conserved 0.0221 0.1043 0.1843
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Brugia malayi fibroinase precursor 0.0224 0.1063 0.1056
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0571 0.2827 0.5019
Leishmania major hypothetical protein, conserved 0.0522 0.2575 0.457
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0512 0.2527 0.2521
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0768 0.3827 0.7826
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0021 0.003 0.003
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0117 0.0793
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0802 0.4002 0.711
Trichomonas vaginalis calmodulin, putative 0.0074 0.0298 0.0594
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.003 0.003
Brugia malayi Thioredoxin reductase 0.0097 0.0413 0.0405
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Brugia malayi Matrixin family protein 0.0024 0.0041 0.0033
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0026 0.0026
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0021 0.003 0.003
Echinococcus multilocularis tissue type plasminogen activator 0.0023 0.0038 0.0038
Loa Loa (eye worm) trypsin family protein 0.0028 0.0063 0.0063
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0092 0.7197
Onchocerca volvulus 0.0976 0.4888 1
Leishmania major cathepsin L-like protease 0.0976 0.4888 0.8688
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Brugia malayi AKH receptor 0.0021 0.003 0.0022
Mycobacterium leprae Probable lipase LipE 0.0039 0.0117 0.0454
Echinococcus granulosus dna polymerase eta 0.0048 0.0165 0.0165
Trypanosoma brucei calpain-like protein, putative 0.088 0.4399 0.7817
Toxoplasma gondii calmodulin CAM1 0.0076 0.031 0.0617
Toxoplasma gondii calcium-dependent protein kinase 0.0076 0.031 0.0617
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0298 0.0594
Echinococcus multilocularis calmodulin 0.0074 0.0298 0.0298
Onchocerca volvulus 0.0076 0.031 0.0575
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0041
Leishmania major small myristoylated protein-2 0.0693 0.3449 0.6126
Loa Loa (eye worm) hypothetical protein 0.0305 0.1472 0.1472
Loa Loa (eye worm) MH2 domain-containing protein 0.0132 0.0592 0.0592
Brugia malayi beta-lactamase family protein 0.0039 0.0117 0.0109
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0092 0.0148
Schistosoma mansoni centrin-related 0.0074 0.0298 0.0298
Entamoeba histolytica cysteine protease, putative 0.0529 0.2614 0.5322
Trypanosoma cruzi major cysteine proteinase, putative 0.0224 0.1063 0.1056
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0245 0.117 0.996
Loa Loa (eye worm) hypothetical protein 0.0305 0.1472 0.1472
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.003 0.003
Trypanosoma brucei mitochondrial calcium uptake 1 0.0074 0.0298 0.0516
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.003 0.003
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0874 0.4365 0.4361
Schistosoma mansoni hypothetical protein 0.0023 0.0038 0.0038
Echinococcus multilocularis centrin 2 0.0074 0.0298 0.0298
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0976 0.4888 0.4888
Trypanosoma cruzi cysteine peptidase, putative 0.0305 0.1472 0.1465
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0117 0.0117
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0028 0.0063 0.0063
Trichomonas vaginalis hypothetical protein 0.0292 0.1405 0.2861
Echinococcus granulosus neuropeptide receptor 0.0021 0.003 0.003
Trypanosoma cruzi trypanothione reductase, putative 0.0097 0.0413 0.0405
Brugia malayi Pre-SET motif family protein 0.0444 0.2178 0.2172
Trypanosoma brucei calmodulin, putative 0.0076 0.031 0.0536
Loa Loa (eye worm) hypothetical protein 0.0065 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0322 0.1561 0.2765
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.003 0.003
Onchocerca volvulus 0.0074 0.0298 0.0552
Trichomonas vaginalis calcium binding protein, putative 0.0074 0.0298 0.0594
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.003 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0221 0.1043 0.1036
Brugia malayi cathepsin L-like precursor 0.0672 0.3337 0.3332
Echinococcus granulosus calpain 7 C02 family 0.0601 0.2976 0.2976
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.003 0.003
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.088 0.4399 0.4394
Brugia malayi hypothetical protein 0.0021 0.003 0.0022
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0092 0.0083
Schistosoma mansoni alpha-1 adrenergic receptor 0.0021 0.003 0.003
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0017 0.0008 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0092 0.0083
Schistosoma mansoni neuropeptide receptor 0.0021 0.003 0.003
Plasmodium vivax vivapain-2 0.0976 0.4888 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0028 0.0063 0.0063
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0512 0.2527 0.2521
Loa Loa (eye worm) hypothetical protein 0.0672 0.3337 0.3337
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0224 0.1063 0.2161
Brugia malayi hypothetical protein 0.0021 0.003 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1121 0.5625 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0117 0.0109
Plasmodium falciparum centrin-1 0.0074 0.0298 0.0594
Echinococcus granulosus prefoldin subunit 6 0.003 0.0076 0.0076
Schistosoma mansoni Mername-AA248 (C02 family) 0.0601 0.2976 0.2976
Loa Loa (eye worm) hypothetical protein 0.0021 0.003 0.003
Schistosoma mansoni calpain-7 (C02 family) 0.0601 0.2976 0.2976
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0074 0.0298 0.029
Onchocerca volvulus 0.0976 0.4888 1
Brugia malayi ORL1-like opioid receptor 0.0021 0.003 0.0022
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0058 0.0089
Brugia malayi Cathepsin L-like precursor 0.0976 0.4888 0.4884
Plasmodium vivax thioredoxin reductase, putative 0.0097 0.0413 0.083
Mycobacterium tuberculosis Probable oxidoreductase 0.0245 0.117 0.996
Brugia malayi Tachykinin-like peptides receptor 99D 0.0021 0.003 0.0022

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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