Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | v-akt murine thymoma viral oncogene homolog 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | metalloprotease disintegrin 16 with thrombospondin type I motif | 0.0057 | 0.1743 | 0.2897 |
Toxoplasma gondii | AGC kinase | 0.0038 | 0.0942 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.004 | 0.1046 | 1 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0028 | 0.0513 | 0.1073 |
Entamoeba histolytica | protein kinase, putative | 0.004 | 0.1046 | 1 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0025 | 0.0396 | 0.0807 |
Schistosoma mansoni | ADAMTS5 peptidase (M12 family) | 0.0057 | 0.1743 | 0.3886 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0025 | 0.0396 | 0.0723 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0025 | 0.0396 | 0.0723 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0028 | 0.0513 | 0.1073 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0231 | 0.032 |
Echinococcus multilocularis | a disintegrin and metalloproteinase with | 0.0057 | 0.1743 | 0.3886 |
Entamoeba histolytica | protein kinase, putative | 0.0038 | 0.0942 | 0.836 |
Brugia malayi | ecdysteroid receptor | 0.0155 | 0.5911 | 1 |
Schistosoma mansoni | adam (A disintegrin and metalloprotease | 0.0021 | 0.0231 | 0.0429 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.1046 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0025 | 0.0396 | 0.0807 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0025 | 0.0396 | 0.0807 |
Schistosoma mansoni | ADAM17 peptidase (M12 family) | 0.012 | 0.4418 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.5911 | 0.5894 |
Echinococcus multilocularis | adam | 0.0021 | 0.0231 | 0.0429 |
Echinococcus granulosus | nervana 2 | 0.0025 | 0.0396 | 0.0723 |
Echinococcus granulosus | Blood coagulation inhibitor Disintegrin | 0.0075 | 0.253 | 0.5096 |
Echinococcus multilocularis | Blood coagulation inhibitor, Disintegrin | 0.0075 | 0.253 | 0.5684 |
Echinococcus multilocularis | adam 17 protease | 0.012 | 0.4418 | 1 |
Echinococcus granulosus | adam 17 protease | 0.0132 | 0.4923 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0025 | 0.0396 | 0.0807 |
Echinococcus granulosus | a disintegrin and metalloproteinase with | 0.0057 | 0.1743 | 0.3484 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0028 | 0.0513 | 1 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0028 | 0.0513 | 0.164 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.1046 | 1 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0028 | 0.0513 | 0.0962 |
Brugia malayi | Protein kinase domain containing protein | 0.004 | 0.1046 | 0.171 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0025 | 0.0408 | 0.0747 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0025 | 0.0408 | 0.5 |
Giardia lamblia | Kinase, AGC PKA | 0.0025 | 0.0408 | 0.5 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.004 | 0.1046 | 0.1008 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0025 | 0.0408 | 0.0747 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0038 | 0.0942 | 0.1531 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.1046 | 1 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0028 | 0.0513 | 0.1073 |
Trypanosoma cruzi | Protein kinase B | 0.0028 | 0.0513 | 1 |
Echinococcus granulosus | adam | 0.0021 | 0.0231 | 0.0385 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.1046 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.1046 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.1046 | 1 |
Echinococcus granulosus | nervana 2 | 0.0025 | 0.0396 | 0.0723 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.004 | 0.1046 | 0.5 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0025 | 0.0408 | 0.0834 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0025 | 0.0408 | 0.5 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0028 | 0.0513 | 0.164 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0038 | 0.0942 | 0.0902 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.1046 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0155 | 0.5911 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.