Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0542 | 1 | 1 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.0204 | 0.3626 | 0.3324 |
Echinococcus multilocularis | aldo keto reductase | 0.0542 | 1 | 1 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0036 | 0.0452 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0542 | 1 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.0204 | 0.3626 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0204 | 0.3626 | 0.3324 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0157 | 0.2735 | 0.2391 |
Echinococcus granulosus | aldehyde reductase | 0.0385 | 0.7038 | 0.6897 |
Loa Loa (eye worm) | oxidoreductase | 0.0542 | 1 | 1 |
Schistosoma mansoni | potassium channel beta | 0.0157 | 0.2735 | 0.2391 |
Onchocerca volvulus | 0.0542 | 1 | 1 | |
Mycobacterium leprae | Possible oxidoreductase | 0.0157 | 0.2735 | 0.2391 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0204 | 0.3626 | 0.1226 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0542 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0298 | 0.5403 | 0.5186 |
Mycobacterium ulcerans | oxidoreductase | 0.0542 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0542 | 1 | 1 |
Trypanosoma cruzi | aldo-keto reductase | 0.0542 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0542 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0542 | 1 | 1 |
Plasmodium falciparum | esterase, putative | 0.0204 | 0.3626 | 1 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0157 | 0.2735 | 0.2391 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0542 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0542 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0542 | 1 | 1 |
Onchocerca volvulus | 0.0542 | 1 | 1 | |
Giardia lamblia | Aldose reductase | 0.0542 | 1 | 0.5 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0157 | 0.2735 | 0.7194 |
Leishmania major | aldo-keto reductase-like protein | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0542 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0542 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0542 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0542 | 1 | 1 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0204 | 0.3626 | 0.1226 |
Brugia malayi | NADH-dependent xylose reductase | 0.0157 | 0.2735 | 0.2391 |
Leishmania major | prostaglandin f synthase, putative | 0.0542 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0157 | 0.2735 | 0.2391 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0298 | 0.5403 | 0.5186 |
Onchocerca volvulus | 0.0542 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0542 | 1 | 1 |
Echinococcus multilocularis | ankyrin repeat protein | 0.0158 | 0.2758 | 0.2415 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0204 | 0.3626 | 0.1226 |
Echinococcus granulosus | aldo keto reductase | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0542 | 1 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0385 | 0.7038 | 0.6897 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0036 | 0.0452 | 0.5 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0157 | 0.2735 | 0.2391 |
Onchocerca volvulus | 0.0542 | 1 | 1 | |
Loa Loa (eye worm) | oxidoreductase | 0.0542 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0204 | 0.3626 | 0.3324 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0204 | 0.3626 | 0.1226 |
Echinococcus multilocularis | aldo keto reductase | 0.0542 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0452 | 0.0452 |
Schistosoma mansoni | amidase | 0.0298 | 0.5403 | 0.5186 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.0204 | 0.3626 | 0.3324 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0157 | 0.2735 | 0.2391 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0298 | 0.5403 | 0.5186 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0036 | 0.0452 | 0.5 |
Leishmania major | monoglyceride lipase, putative | 0.0204 | 0.3626 | 0.3626 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.0157 | 0.2735 | 0.2391 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0542 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0385 | 0.7038 | 0.6897 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0542 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0158 | 0.2762 | 0.242 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0158 | 0.2758 | 0.2415 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0204 | 0.3626 | 0.1226 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0542 | 1 | 1 |
Mycobacterium ulcerans | lysophospholipase | 0.0204 | 0.3626 | 0.3324 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0204 | 0.3626 | 0.1226 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0157 | 0.2735 | 0.7194 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0542 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0542 | 1 | 1 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0204 | 0.3626 | 0.1226 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0542 | 1 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.0204 | 0.3626 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0542 | 1 | 1 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0157 | 0.2735 | 0.2735 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0542 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.0542 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0542 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0157 | 0.2735 | 0.2391 |
Entamoeba histolytica | aldose reductase, putative | 0.0542 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0204 | 0.3626 | 0.1226 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0204 | 0.3626 | 0.1226 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0542 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0542 | 1 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.0204 | 0.3626 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0298 | 0.5403 | 0.5186 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.5403 | 0.5186 |
Entamoeba histolytica | aldose reductase, putative | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0542 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0204 | 0.3626 | 0.1226 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0542 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Onchocerca volvulus | 0.0542 | 1 | 1 | |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0157 | 0.2735 | 0.7194 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0542 | 1 | 1 |
Plasmodium vivax | PST-A protein | 0.0204 | 0.3626 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0542 | 1 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0298 | 0.5403 | 0.5186 |
Onchocerca volvulus | 0.0542 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0157 | 0.2735 | 0.2391 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0542 | 1 | 1 |
Brugia malayi | amidase | 0.0298 | 0.5403 | 0.5186 |
Plasmodium vivax | aldehyde reductase, putative | 0.0157 | 0.2735 | 0.7194 |
Mycobacterium tuberculosis | Conserved protein | 0.0157 | 0.2735 | 0.2391 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.0158 | 0.2758 | 0.2415 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0542 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0542 | 1 | 1 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0204 | 0.3626 | 0.3324 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0204 | 0.3626 | 0.3324 |
Echinococcus granulosus | ankyrin repeat protein | 0.0158 | 0.2758 | 0.2415 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0542 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.