Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Schistosoma mansoni | aldo-keto reductase | 0.0401 | 0.2778 | 0.2778 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Trypanosoma brucei | prostaglandin f synthase | 0.0401 | 0.2778 | 0.4927 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0678 | 0.5639 | 1 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0678 | 0.5639 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0401 | 0.2778 | 0.2778 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0401 | 0.2778 | 0.2778 |
Echinococcus granulosus | aldo keto reductase | 0.0401 | 0.2778 | 0.2778 |
Plasmodium falciparum | lysophospholipase, putative | 0.0678 | 0.5639 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0401 | 0.2778 | 0.2778 |
Echinococcus multilocularis | aldo keto reductase | 0.0401 | 0.2778 | 0.2778 |
Onchocerca volvulus | 0.0401 | 0.2778 | 0.5 | |
Schistosoma mansoni | amidase | 0.11 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0678 | 0.5639 | 1 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0133 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0401 | 0.2778 | 0.2778 |
Giardia lamblia | Aldose reductase | 0.0401 | 0.2778 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0401 | 0.2778 | 0.2778 |
Echinococcus granulosus | hypothetical protein | 0.0401 | 0.2778 | 0.2778 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Onchocerca volvulus | 0.0401 | 0.2778 | 0.5 | |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0401 | 0.2778 | 0.4927 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0401 | 0.2778 | 0.2778 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0678 | 0.5639 | 1 |
Onchocerca volvulus | 0.0401 | 0.2778 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0401 | 0.2778 | 0.2778 |
Trypanosoma cruzi | aldo-keto reductase | 0.0401 | 0.2778 | 0.4927 |
Plasmodium vivax | PST-A protein | 0.0678 | 0.5639 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0678 | 0.5639 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.11 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0401 | 0.2778 | 0.4927 |
Leishmania major | prostaglandin f synthase, putative | 0.0401 | 0.2778 | 0.4927 |
Leishmania major | aldo-keto reductase-like protein | 0.0401 | 0.2778 | 0.4927 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0401 | 0.2778 | 0.2778 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0401 | 0.2778 | 0.4927 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0678 | 0.5639 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Mycobacterium ulcerans | hypothetical protein | 0.0678 | 0.5639 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0401 | 0.2778 | 0.2778 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0401 | 0.2778 | 0.4927 |
Echinococcus multilocularis | aldo keto reductase | 0.0401 | 0.2778 | 0.2778 |
Loa Loa (eye worm) | hypothetical protein | 0.0401 | 0.2778 | 0.2778 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0401 | 0.2778 | 0.2778 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0678 | 0.5639 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0401 | 0.2778 | 0.2778 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0133 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0678 | 0.5639 | 1 |
Leishmania major | monoglyceride lipase, putative | 0.0678 | 0.5639 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.0678 | 0.5639 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0401 | 0.2778 | 0.2778 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0678 | 0.5639 | 1 |
Onchocerca volvulus | 0.0401 | 0.2778 | 0.5 | |
Echinococcus granulosus | aldo keto reductase | 0.0401 | 0.2778 | 0.2778 |
Giardia lamblia | Aldose reductase | 0.0401 | 0.2778 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0678 | 0.5639 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0401 | 0.2778 | 0.2778 |
Toxoplasma gondii | aldose reductase, putative | 0.0401 | 0.2778 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0678 | 0.5639 | 1 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.0678 | 0.5639 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.11 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0401 | 0.2778 | 0.2778 |
Loa Loa (eye worm) | oxidoreductase | 0.0401 | 0.2778 | 0.2778 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0401 | 0.2778 | 0.4927 |
Plasmodium falciparum | esterase, putative | 0.0678 | 0.5639 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0401 | 0.2778 | 0.2778 |
Plasmodium falciparum | lysophospholipase, putative | 0.0678 | 0.5639 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0401 | 0.2778 | 0.2778 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.0678 | 0.5639 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0401 | 0.2778 | 0.2778 |
Loa Loa (eye worm) | hypothetical protein | 0.11 | 1 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0401 | 0.2778 | 0.4927 |
Echinococcus granulosus | aldehyde reductase | 0.0285 | 0.1576 | 0.1576 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.11 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0401 | 0.2778 | 0.2778 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.11 | 1 | 1 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.11 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0133 | 0 | 0.5 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0678 | 0.5639 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0285 | 0.1576 | 0.1576 |
Mycobacterium ulcerans | oxidoreductase | 0.0401 | 0.2778 | 0.4927 |
Echinococcus multilocularis | aldo keto reductase | 0.0401 | 0.2778 | 0.2778 |
Onchocerca volvulus | 0.0401 | 0.2778 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0401 | 0.2778 | 0.2778 |
Schistosoma mansoni | pol-related | 0.0401 | 0.2778 | 0.2778 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0285 | 0.1576 | 0.2796 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0678 | 0.5639 | 1 |
Mycobacterium ulcerans | lysophospholipase | 0.0678 | 0.5639 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0401 | 0.2778 | 0.2778 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0401 | 0.2778 | 0.2778 |
Onchocerca volvulus | 0.0401 | 0.2778 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.