Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | acetylcholinesterase | 0.3934 | 1 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.1812 | 0.3508 | 1 |
Onchocerca volvulus | 0.0665 | 0 | 0.5 | |
Onchocerca volvulus | 0.0665 | 0 | 0.5 | |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0665 | 0 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.3934 | 1 | 1 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.1684 | 0.3118 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3934 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.3934 | 1 | 1 |
Onchocerca volvulus | 0.0665 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.3934 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.3934 | 1 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.1812 | 0.3508 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0665 | 0 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.3934 | 1 | 1 |
Onchocerca volvulus | 0.0665 | 0 | 0.5 | |
Onchocerca volvulus | 0.0665 | 0 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.3934 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3934 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.3934 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.3934 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.3934 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.