Detailed information for compound 1463408

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 488.338 | Formula: C21H23IN4O2
  • H donors: 0 H acceptors: 1 LogP: 5.77 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: [N-]=[N+]=Nc1ccc(cc1)CN1CCCC[C@@H]1[C@@H](c1ccc(cc1)[125I])C(=O)OC
  • InChi: 1S/C21H23IN4O2/c1-28-21(27)20(16-7-9-17(22)10-8-16)19-4-2-3-13-26(19)14-15-5-11-18(12-6-15)24-25-23/h5-12,19-20H,2-4,13-14H2,1H3/t19-,20-/m1/s1/i22-2
  • InChiKey: PLSLYUFKIKYVII-GUXLZLHYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.0011 0.0015
Brugia malayi hypothetical protein 0.0019 0.0011 0.002
Trichomonas vaginalis spcc417.12 protein, putative 0.0339 0.0876 0.8697
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.2007 0.5378 1
Echinococcus granulosus lysine specific histone demethylase 1A 0.0262 0.0667 0.1237
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0262 0.0667 0.1224
Brugia malayi Carboxylesterase family protein 0.0339 0.0876 0.1628
Loa Loa (eye worm) hypothetical protein 0.0273 0.0696 0.1294
Leishmania major hypothetical protein, conserved 0.0021 0.0017 0.025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0021 0.0017 0.0011
Mycobacterium tuberculosis Probable lipase LipD 0.0021 0.0017 0.0018
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0039 0.0066 0.0117
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Echinococcus granulosus lamin 0.0032 0.0048 0.0084
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.0161 0.03
Loa Loa (eye worm) acetylcholinesterase 1 0.2007 0.5378 1
Echinococcus multilocularis protoporphyrinogen oxidase 0.0262 0.0667 0.1237
Brugia malayi MH2 domain containing protein 0.0069 0.0147 0.0273
Loa Loa (eye worm) hypothetical protein 0.0071 0.0152 0.0282
Onchocerca volvulus 0.0032 0.0048 0.0474
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0133 0.032 0.0344
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.002
Entamoeba histolytica acyl-coA synthetase, putative 0.0015 0 0.5
Trypanosoma cruzi UDP-galactopyranose mutase 0.0262 0.0667 1
Onchocerca volvulus 0.0109 0.0256 0.2548
Echinococcus multilocularis 0.0262 0.0667 0.1237
Toxoplasma gondii ABC1 family protein 0.0021 0.0017 0.0093
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0207 0.0366
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0262 0.0667 0.0667
Mycobacterium tuberculosis Probable esterase LipL 0.0021 0.0017 0.0018
Onchocerca volvulus 0.0339 0.0876 0.8718
Brugia malayi Pre-SET motif family protein 0.0049 0.0092 0.0171
Loa Loa (eye worm) hypothetical protein 0.0339 0.0876 0.1628
Schistosoma mansoni sodium/chloride dependent transporter 0.0109 0.0256 0.0457
Loa Loa (eye worm) hypothetical protein 0.0262 0.0667 0.1241
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0339 0.0876 0.8697
Mycobacterium tuberculosis Probable hydrolase 0.0021 0.0017 0.0018
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.3457 0.9293 1
Echinococcus multilocularis lamin 0.0032 0.0048 0.0084
Plasmodium vivax hypothetical protein, conserved 0.0262 0.0667 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0031
Schistosoma mansoni microtubule-associated protein tau 0.0427 0.1114 0.2055
Echinococcus granulosus lysine specific histone demethylase 1A 0.0262 0.0667 0.1237
Echinococcus multilocularis geminin 0.0288 0.0738 0.1368
Loa Loa (eye worm) hypothetical protein 0.0339 0.0876 0.1628
Brugia malayi latrophilin 2 splice variant baaae 0.0084 0.0188 0.0349
Echinococcus granulosus intermediate filament protein 0.0032 0.0048 0.0084
Schistosoma mansoni hypothetical protein 0.0039 0.0066 0.0103
Mycobacterium tuberculosis Conserved protein 0.0021 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0071 0.0152 0.0282
Onchocerca volvulus 0.0019 0.0011 0.0105
Onchocerca volvulus 0.0021 0.0017 0.0166
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0021 0.0017 0.0031
Schistosoma mansoni gliotactin 0.0339 0.0876 0.1612
Loa Loa (eye worm) hypothetical protein 0.0339 0.0876 0.1628
Brugia malayi hypothetical protein 0.0273 0.0696 0.1294
Loa Loa (eye worm) serotonin transporter b 0.0109 0.0256 0.0476
Brugia malayi Pre-SET motif family protein 0.034 0.0878 0.1632
Schistosoma mansoni amine oxidase 0.0262 0.0667 0.1224
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0207 0.038
Schistosoma mansoni lamin 0.0032 0.0048 0.0069
Brugia malayi Carboxylesterase family protein 0.2007 0.5378 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0262 0.0667 1
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0262 0.0667 0.1224
Echinococcus granulosus beta LACTamase domain containing family member 0.0021 0.0017 0.0026
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0262 0.0667 1
Mycobacterium ulcerans beta-lactamase 0.0021 0.0017 0.0017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0207 0.038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0207 0.0366
Onchocerca volvulus 0.0021 0.0017 0.0166
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0339 0.0876 0.0942
Loa Loa (eye worm) beta-lactamase 0.0021 0.0017 0.0031
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0048 0.0089
Brugia malayi Ets-domain containing protein 0.0074 0.0161 0.03
Loa Loa (eye worm) hypothetical protein 0.0123 0.0293 0.0545
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0019 0.0011 0.0015
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0017 0.5
Echinococcus multilocularis para nitrobenzyl esterase 0.0339 0.0876 0.1625
Echinococcus multilocularis GPCR, family 2 0.0039 0.0066 0.0117
Loa Loa (eye worm) hypothetical protein 0.0064 0.0132 0.0246
Loa Loa (eye worm) norepinephrine transporter 0.0109 0.0256 0.0476
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0031
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0339 0.0876 0.1612
Mycobacterium ulcerans esterase/lipase LipP 0.0021 0.0017 0.0017
Loa Loa (eye worm) carboxylesterase 0.0339 0.0876 0.1628
Loa Loa (eye worm) solute carrier family 6 member 4 0.0109 0.0256 0.0476
Brugia malayi Fli-1 protein 0.0226 0.057 0.106
Brugia malayi hypothetical protein 0.0071 0.0152 0.0282
Mycobacterium ulcerans dehydrogenase 0.0262 0.0667 0.0667
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0019 0.0011 0.002
Brugia malayi hypothetical protein 0.0339 0.0876 0.1628
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0021 0.0017 0.0018
Schistosoma mansoni intermediate filament proteins 0.0032 0.0048 0.0069
Echinococcus granulosus neuroligin 0.0339 0.0876 0.1625
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0031
Mycobacterium tuberculosis Possible oxidoreductase 0.0262 0.0667 0.0718
Loa Loa (eye worm) hypothetical protein 0.0032 0.0048 0.0089
Schistosoma mansoni lamin 0.0032 0.0048 0.0069
Loa Loa (eye worm) hypothetical protein 0.0339 0.0876 0.1628
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.002
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0092 0.0166
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.0011 0.0015
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.0011 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0339 0.0876 0.1628
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0109 0.0256 0.0476
Schistosoma mansoni gabp alpha 0.0074 0.0161 0.0281
Loa Loa (eye worm) hypothetical protein 0.2007 0.5378 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0339 0.0876 0.0942
Schistosoma mansoni survival motor neuron protein 0.0056 0.011 0.0186
Echinococcus granulosus lamin dm0 0.0032 0.0048 0.0084
Loa Loa (eye worm) hypothetical protein 0.2007 0.5378 1
Echinococcus granulosus microtubule associated protein 2 0.0427 0.1114 0.2067
Brugia malayi intermediate filament protein 0.0032 0.0048 0.0089
Mycobacterium leprae Probable lipase LipE 0.0021 0.0017 0.025
Onchocerca volvulus 0.0339 0.0876 0.8718
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0262 0.0667 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0021 0.0017 0.0017
Loa Loa (eye worm) transcription factor SMAD2 0.0069 0.0147 0.0273
Echinococcus multilocularis survival motor neuron protein 1 0.0273 0.0696 0.129
Schistosoma mansoni BC026374 protein (S09 family) 0.0339 0.0876 0.1612
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0092 0.0152
Loa Loa (eye worm) hypothetical protein 0.0016 0.0002 0.0005
Echinococcus multilocularis microtubule associated protein 2 0.0427 0.1114 0.2067
Loa Loa (eye worm) carboxylesterase 0.2007 0.5378 1
Mycobacterium tuberculosis Probable lipase LipE 0.0021 0.0017 0.0018
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0262 0.0667 0.1237
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0031
Mycobacterium ulcerans oxidoreductase 0.0262 0.0667 0.0667
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.002
Echinococcus multilocularis sodium and chloride dependent glycine 0.0019 0.0011 0.0015
Brugia malayi hypothetical protein 0.0262 0.0667 0.1241
Schistosoma mansoni hypothetical protein 0.0288 0.0738 0.1355
Brugia malayi Carboxylesterase family protein 0.0339 0.0876 0.1628
Onchocerca volvulus 0.0019 0.0011 0.0105
Mycobacterium ulcerans carboxylesterase, LipT 0.0339 0.0876 0.0876
Loa Loa (eye worm) hypothetical protein 0.0109 0.0256 0.0476
Onchocerca volvulus 0.0339 0.0876 0.8718
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0049 0.0092 0.0166
Entamoeba histolytica acyl-CoA synthetase, putative 0.0015 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.002
Echinococcus granulosus geminin 0.0288 0.0738 0.1368
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0092 0.0152
Brugia malayi Latrophilin receptor protein 2 0.0039 0.0066 0.0122
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.0161 0.0295
Toxoplasma gondii histone lysine-specific demethylase 0.0262 0.0667 1
Onchocerca volvulus Huntingtin homolog 0.0071 0.0152 0.1512
Mycobacterium ulcerans monoamine oxidase 0.0262 0.0667 0.0667
Plasmodium falciparum protoporphyrinogen oxidase 0.0262 0.0667 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.002
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0048 0.0089
Loa Loa (eye worm) hypothetical protein 0.0084 0.0188 0.0349
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.002
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0339 0.0876 0.1612
Brugia malayi SWIRM domain containing protein 0.0262 0.0667 0.1241
Brugia malayi beta-lactamase 0.0021 0.0017 0.0031
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0339 0.0876 0.1612
Echinococcus multilocularis beta LACTamase domain containing family member 0.0021 0.0017 0.0026
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.0161 0.0295
Brugia malayi Carboxylesterase family protein 0.0339 0.0876 0.1628
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0092 0.0166
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.002
Echinococcus granulosus para nitrobenzyl esterase 0.0339 0.0876 0.1625
Echinococcus multilocularis acetylcholinesterase 0.2007 0.5378 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.034 0.0878 0.1632
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0092 0.0152
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0021 0.0017 0.0018
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0019 0.0011 0.0015
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0262 0.0667 1
Brugia malayi Ets-domain containing protein 0.0074 0.0161 0.03
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0031
Echinococcus granulosus acetylcholinesterase 0.2007 0.5378 1
Trypanosoma cruzi UDP-galactopyranose mutase 0.0262 0.0667 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0039 0.0066 0.0122
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0207 0.0385
Loa Loa (eye worm) hypothetical protein 0.0339 0.0876 0.1628
Mycobacterium tuberculosis Conserved protein 0.0021 0.0017 0.0018
Loa Loa (eye worm) carboxylesterase 0.0339 0.0876 0.1628
Brugia malayi Calcitonin receptor-like protein seb-1 0.0123 0.0293 0.0545
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0019 0.0011 0.0015
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0021 0.0017 0.0018
Onchocerca volvulus 0.0049 0.0092 0.0915
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0339 0.0876 0.1625
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0019 0.0011 0.0015
Onchocerca volvulus 0.0339 0.0876 0.8718
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0017 0.0093
Schistosoma mansoni hypothetical protein 0.0039 0.0066 0.0103
Echinococcus multilocularis acetylcholinesterase 0.2007 0.5378 1
Loa Loa (eye worm) hypothetical protein 0.0262 0.0667 0.1241
Chlamydia trachomatis protoporphyrinogen oxidase 0.0262 0.0667 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.002
Loa Loa (eye worm) MH2 domain-containing protein 0.0069 0.0147 0.0273
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0123 0.0293 0.0545
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0047 0.0087 0.0157
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0339 0.0876 0.1625
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0019 0.0011 0.0015
Onchocerca volvulus 0.0021 0.0017 0.0166
Loa Loa (eye worm) latrophilin receptor protein 2 0.0039 0.0066 0.0122
Echinococcus granulosus BC026374 protein S09 family 0.0339 0.0876 0.1625
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0019 0.0011 0.002
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0039 0.0066 0.0117
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0207 0.038
Schistosoma mansoni hypothetical protein 0.0288 0.0738 0.1355
Loa Loa (eye worm) hypothetical protein 0.0262 0.0667 0.1241
Loa Loa (eye worm) fli-1 protein 0.0226 0.057 0.106
Onchocerca volvulus 0.0019 0.0011 0.0105
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0049 0.0092 0.0152
Mycobacterium tuberculosis Conserved protein 0.0021 0.0017 0.0018
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0017 0.025
Entamoeba histolytica acyl-CoA synthetase, putative 0.0015 0 0.5
Leishmania major UDP-galactopyranose mutase 0.0262 0.0667 1
Treponema pallidum sodium- and chloride- dependent transporter 0.0109 0.0256 0.5
Schistosoma mansoni acetylcholinesterase 0.0339 0.0876 0.1612
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0207 0.038
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0048 0.0089
Onchocerca volvulus 0.0387 0.1005 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0011 0.002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0046 0.0086
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0123 0.0293 0.0545
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.3719 1 1
Mycobacterium ulcerans hypothetical protein 0.0021 0.0017 0.0017
Trichomonas vaginalis set domain proteins, putative 0.0387 0.1005 1
Mycobacterium ulcerans lipase LipD 0.0021 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0039 0.0066 0.0103
Brugia malayi amine oxidase, flavin-containing family protein 0.0262 0.0667 0.1241
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0207 0.0366
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0207 0.0385
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0021 0.0017 0.0011
Echinococcus granulosus carboxylesterase 5A 0.2007 0.5378 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0066 0.0122
Schistosoma mansoni hypothetical protein 0.0084 0.0188 0.033
Echinococcus multilocularis musashi 0.0032 0.0048 0.0084
Echinococcus multilocularis carboxylesterase 5A 0.2007 0.5378 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0021 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0262 0.0667 0.1241
Onchocerca volvulus 0.0032 0.0048 0.0474
Loa Loa (eye worm) hypothetical protein 0.0339 0.0876 0.1628
Schistosoma mansoni neuroligin 3 (S09 family) 0.0339 0.0876 0.1612
Brugia malayi beta-lactamase family protein 0.0021 0.0017 0.0031
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.011 0.0205
Echinococcus multilocularis lamin dm0 0.0032 0.0048 0.0084
Schistosoma mansoni amine oxidase 0.0262 0.0667 0.1224
Schistosoma mansoni hypothetical protein 0.0056 0.011 0.0186
Echinococcus granulosus acetylcholinesterase 0.2007 0.5378 1
Onchocerca volvulus 0.0339 0.0876 0.8718
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0019 0.0011 0.0015
Onchocerca volvulus 0.0056 0.011 0.11
Onchocerca volvulus Huntingtin homolog 0.0071 0.0152 0.1512
Schistosoma mansoni ets-related 0.0226 0.057 0.1042
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0262 0.0667 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0262 0.0667 0.0718
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0109 0.0256 0.0457
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0007 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0262 0.0667 1
Echinococcus granulosus sodium and chloride dependent glycine 0.0019 0.0011 0.0015
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0339 0.0876 0.0942
Loa Loa (eye worm) hypothetical protein 0.0262 0.0667 0.1241
Brugia malayi Carboxylesterase family protein 0.0339 0.0876 0.1628
Loa Loa (eye worm) hypothetical protein 0.0109 0.0256 0.0476
Echinococcus granulosus serotonin transporter 0.0109 0.0256 0.0472
Echinococcus multilocularis neuroligin 0.0339 0.0876 0.1625
Loa Loa (eye worm) hypothetical protein 0.0109 0.0256 0.0476
Echinococcus multilocularis BC026374 protein (S09 family) 0.0339 0.0876 0.1625
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0031
Onchocerca volvulus 0.0262 0.0667 0.6644
Brugia malayi beta-lactamase family protein 0.0021 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0262 0.0667 0.1241
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0007 0.0013
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0262 0.0667 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0049 0.0092 0.1239
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0039 0.0066 0.0117
Echinococcus granulosus survival motor neuron protein 1 0.0273 0.0696 0.129
Brugia malayi Carboxylesterase family protein 0.2007 0.5378 1
Plasmodium vivax SET domain protein, putative 0.0049 0.0092 0.1239
Echinococcus multilocularis serotonin transporter 0.0109 0.0256 0.0472
Schistosoma mansoni hypothetical protein 0.0039 0.0066 0.0103
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0039 0.0066 0.0117
Loa Loa (eye worm) hypothetical protein 0.0049 0.0092 0.0171
Echinococcus granulosus GPCR family 2 0.0039 0.0066 0.0117

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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