Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | carboxylesterase 5A | 0.1672 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0074 | 0.0074 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0282 | 0.1503 | 0.1461 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1503 | 0.1461 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0057 | 0.0124 | 0.5 |
Brugia malayi | hypothetical protein | 0.0057 | 0.0124 | 0.0124 |
Schistosoma mansoni | acetylcholinesterase | 0.0282 | 0.1503 | 0.1461 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0074 | 0.0025 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0282 | 0.1503 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1672 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0282 | 0.1503 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0282 | 0.1503 | 0.1461 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0074 | 0.0025 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0074 | 0.0074 |
Loa Loa (eye worm) | hypothetical protein | 0.1672 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1503 | 0.1461 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0057 | 0.0124 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1672 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0282 | 0.1503 | 0.1461 |
Onchocerca volvulus | 0.0282 | 0.1503 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1503 | 0.1461 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0282 | 0.1503 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0057 | 0.0124 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0282 | 0.1503 | 0.1461 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1503 | 0.1461 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0282 | 0.1503 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1672 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0282 | 0.1503 | 0.1461 |
Brugia malayi | Carboxylesterase family protein | 0.0282 | 0.1503 | 0.1503 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0124 | 0.0075 |
Echinococcus multilocularis | neuroligin | 0.0282 | 0.1503 | 0.1461 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0282 | 0.1503 | 0.1461 |
Onchocerca volvulus | 0.0282 | 0.1503 | 0.5 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0282 | 0.1503 | 0.1461 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0057 | 0.0124 | 0.5 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0282 | 0.1503 | 0.1461 |
Echinococcus granulosus | geminin | 0.0177 | 0.0859 | 0.0814 |
Brugia malayi | Carboxylesterase family protein | 0.0282 | 0.1503 | 0.1503 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0282 | 0.1503 | 0.1461 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0282 | 0.1503 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.1672 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0057 | 0.0124 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0282 | 0.1503 | 0.1503 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0282 | 0.1503 | 0.1461 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0057 | 0.0124 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0282 | 0.1503 | 0.1461 |
Brugia malayi | Carboxylesterase family protein | 0.1672 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1672 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0177 | 0.0859 | 0.0814 |
Loa Loa (eye worm) | carboxylesterase | 0.1672 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0282 | 0.1503 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0057 | 0.0124 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1672 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0049 | 0.0049 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0282 | 0.1503 | 0.1461 |
Echinococcus multilocularis | acetylcholinesterase | 0.1672 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0282 | 0.1503 | 0.1503 |
Echinococcus granulosus | neuroligin | 0.0282 | 0.1503 | 0.1461 |
Loa Loa (eye worm) | carboxylesterase | 0.0282 | 0.1503 | 0.1461 |
Onchocerca volvulus | 0.0282 | 0.1503 | 0.5 | |
Onchocerca volvulus | 0.0282 | 0.1503 | 0.5 | |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0057 | 0.0124 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1503 | 0.1461 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.0859 | 0.0814 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 0.0859 | 0.0814 |
Brugia malayi | hypothetical protein | 0.0282 | 0.1503 | 0.1503 |
Echinococcus granulosus | acetylcholinesterase | 0.1672 | 1 | 1 |
Onchocerca volvulus | 0.0282 | 0.1503 | 0.5 | |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0282 | 0.1503 | 0.1461 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1503 | 0.1461 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1503 | 0.1461 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.