Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | carboxylesterase | 0.0349 | 0.1603 | 0.1567 |
Leishmania major | prostaglandin f synthase, putative | 0.003 | 0.0042 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0349 | 0.1603 | 0.1603 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus multilocularis | aldo keto reductase | 0.003 | 0.0042 | 0.0042 |
Echinococcus granulosus | neuroligin | 0.0349 | 0.1603 | 0.1603 |
Loa Loa (eye worm) | carboxylesterase | 0.2066 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0043 | 0.0107 | 0.0065 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0349 | 0.1603 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.2066 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0349 | 0.1603 | 0.1567 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0349 | 0.1603 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.003 | 0.0042 | 0.5 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.003 | 0.0042 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0349 | 0.1603 | 0.1567 |
Echinococcus granulosus | acetylcholinesterase | 0.2066 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0043 | 0.0107 | 0.0107 |
Trypanosoma cruzi | aldo-keto reductase | 0.003 | 0.0042 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.003 | 0.0042 | 0.0042 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0349 | 0.1603 | 0.1603 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.1603 | 0.1567 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.2066 | 1 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.003 | 0.0042 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.003 | 0.0042 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0349 | 0.1603 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.003 | 0.0042 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0043 | 0.0107 | 0.0065 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0349 | 0.1603 | 0.1567 |
Toxoplasma gondii | aldose reductase, putative | 0.003 | 0.0042 | 0.5 |
Onchocerca volvulus | 0.0349 | 0.1603 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.1603 | 0.1567 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0349 | 0.1603 | 0.1567 |
Echinococcus granulosus | hypothetical protein | 0.003 | 0.0042 | 0.0042 |
Giardia lamblia | Aldose reductase | 0.003 | 0.0042 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus multilocularis | neuroligin | 0.0349 | 0.1603 | 0.1603 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus multilocularis | acetylcholinesterase | 0.2066 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0349 | 0.1603 | 0.1567 |
Schistosoma mansoni | gliotactin | 0.0349 | 0.1603 | 0.1567 |
Echinococcus granulosus | aldo keto reductase | 0.003 | 0.0042 | 0.0042 |
Echinococcus multilocularis | aldo keto reductase | 0.003 | 0.0042 | 0.0042 |
Onchocerca volvulus | 0.0349 | 0.1603 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.1603 | 0.1567 |
Echinococcus multilocularis | aldo keto reductase | 0.003 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.1603 | 0.1567 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0043 | 0.0107 | 0.0065 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0349 | 0.1603 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus multilocularis | acetylcholinesterase | 0.2066 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0043 | 0.0107 | 0.0065 |
Entamoeba histolytica | aldose reductase, putative | 0.003 | 0.0042 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.2066 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.003 | 0.0042 | 0.0042 |
Brugia malayi | Carboxylesterase family protein | 0.2066 | 1 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0349 | 0.1603 | 0.1603 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.003 | 0.0042 | 0.0042 |
Brugia malayi | hypothetical protein | 0.0349 | 0.1603 | 0.1567 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0349 | 0.1603 | 0.1567 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0043 | 0.0107 | 0.0065 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.003 | 0.0042 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.003 | 0.0042 | 0.0042 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0349 | 0.1603 | 0.1567 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.003 | 0.0042 | 0.0042 |
Schistosoma mansoni | acetylcholinesterase | 0.0349 | 0.1603 | 0.1567 |
Echinococcus granulosus | acetylcholinesterase | 0.2066 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.1603 | 0.1567 |
Echinococcus granulosus | aldo keto reductase | 0.003 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.1603 | 0.1567 |
Onchocerca volvulus | 0.0349 | 0.1603 | 1 | |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0349 | 0.1603 | 0.1603 |
Loa Loa (eye worm) | carboxylesterase | 0.0349 | 0.1603 | 0.1567 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0349 | 0.1603 | 0.1567 |
Echinococcus granulosus | carboxylesterase 5A | 0.2066 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0043 | 0.0107 | 0.0107 |
Trypanosoma brucei | prostaglandin f synthase | 0.003 | 0.0042 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0043 | 0.0107 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.1603 | 0.1567 |
Giardia lamblia | Aldose reductase | 0.003 | 0.0042 | 0.5 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.003 | 0.0042 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0349 | 0.1603 | 0.1603 |
Onchocerca volvulus | 0.0349 | 0.1603 | 1 | |
Entamoeba histolytica | aldose reductase, putative | 0.003 | 0.0042 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.003 | 0.0042 | 0.0042 |
Onchocerca volvulus | 0.0349 | 0.1603 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0349 | 0.1603 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0349 | 0.1603 | 0.1567 |
Loa Loa (eye worm) | hypothetical protein | 0.2066 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.003 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.2066 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0043 | 0.0107 | 0.0107 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.003 | 0.0042 | 0.0042 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.003 | 0.0042 | 0.0042 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0349 | 0.1603 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0349 | 0.1603 | 0.1603 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.