Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cystathionine beta-synthase | 0.014 | 0.5 | 0.5 |
Brugia malayi | cbs-prov protein | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | cystathionine beta-synthase, putative | 0.014 | 0.5 | 0.5 |
Toxoplasma gondii | pyridoxal-phosphate dependent superfamily protein | 0.014 | 0.5 | 0.5 |
Entamoeba histolytica | cysteine synthase A, putative | 0.014 | 0.5 | 0.5 |
Trichomonas vaginalis | threonine synthase, putative | 0.014 | 0.5 | 0.5 |
Entamoeba histolytica | cysteine synthase A, putative | 0.014 | 0.5 | 0.5 |
Schistosoma mansoni | cysteine synthase | 0.014 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable cystathionine beta-synthase Cbs (serine sulfhydrase) (beta-thionase) (hemoprotein H-450) | 0.014 | 0.5 | 0.5 |
Trichomonas vaginalis | threonine synthase, putative | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | cystathionine beta-synthase | 0.014 | 0.5 | 0.5 |
Mycobacterium leprae | Probable cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (Hemoprotein H-450) | 0.014 | 0.5 | 0.5 |
Trichomonas vaginalis | cysteine synthase, putative | 0.014 | 0.5 | 0.5 |
Schistosoma mansoni | cysteine synthase | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | serine sulfhydrylase | 0.014 | 0.5 | 0.5 |
Trichomonas vaginalis | cysteine synthase, putative | 0.014 | 0.5 | 0.5 |
Trichomonas vaginalis | cysteine synthase, putative | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | cystathionine beta-synthase | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | cystathionine beta-synthase, putative | 0.014 | 0.5 | 0.5 |
Mycobacterium ulcerans | cysteine synthase B | 0.014 | 0.5 | 0.5 |
Mycobacterium ulcerans | cystathionine beta-synthase | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | serine sulfhydrylase | 0.014 | 0.5 | 0.5 |
Trichomonas vaginalis | cysteine synthase, putative | 0.014 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Cysteine synthase a CysK1 (O-acetylserine sulfhydrylase A) (O-acetylserine (thiol)-lyase A) (CSASE A) | 0.014 | 0.5 | 0.5 |
Leishmania major | cysteine synthase | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | cysteine synthase, putative | 0.014 | 0.5 | 0.5 |
Trichomonas vaginalis | cysteine synthase, putative | 0.014 | 0.5 | 0.5 |
Entamoeba histolytica | cysteine synthase A, putative | 0.014 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Cysteine synthase B CysM (CSASE B) (O-phosphoserine sulfhydrylase B) (O-phosphoserine (thiol)-lyase B) | 0.014 | 0.5 | 0.5 |
Loa Loa (eye worm) | cbs-prov protein | 0.014 | 0.5 | 0.5 |
Leishmania major | cystathionine beta-synthase | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | cystathionine beta-synthase, putative | 0.014 | 0.5 | 0.5 |
Mycobacterium leprae | PROBABLE CYSTEINE SYNTHASE A CYSK (O-ACETYLSERINE SULFHYDRYLASE A) (O-ACETYLSERINE (THIOL)-LYASE A) (CSASE A) | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | cysteine synthase, putative | 0.014 | 0.5 | 0.5 |
Trypanosoma brucei | cystathionine beta-synthase, putative | 0.014 | 0.5 | 0.5 |
Trichomonas vaginalis | cysteine synthase, putative | 0.014 | 0.5 | 0.5 |
Toxoplasma gondii | CBS family protein | 0.014 | 0.5 | 0.5 |
Mycobacterium ulcerans | cysteine synthase a CysK1 | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | serine sulfhydrylase | 0.014 | 0.5 | 0.5 |
Trypanosoma cruzi | serine sulfhydrylase | 0.014 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.