Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1338 | 0.6337 | 0.6337 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0716 | 0.3323 | 0.5218 |
Onchocerca volvulus | 0.0228 | 0.0958 | 0.1483 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Loa Loa (eye worm) | hypothetical protein | 0.0424 | 0.1906 | 0.1906 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1602 | 0.7622 | 0.7622 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0292 | 0.1268 | 0.1974 |
Leishmania major | cathepsin L-like protease | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0716 | 0.3323 | 0.5218 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0424 | 0.1906 | 0.1889 |
Onchocerca volvulus | 0.0051 | 0.0097 | 0.0121 | |
Loa Loa (eye worm) | hypothetical protein | 0.0292 | 0.1268 | 0.1268 |
Onchocerca volvulus | 0.1338 | 0.6337 | 1 | |
Onchocerca volvulus | 0.0914 | 0.4282 | 0.6746 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0035 | 0.0035 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0292 | 0.1268 | 0.1268 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0085 | 0.0085 |
Echinococcus granulosus | cathepsin b | 0.2093 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2093 | 1 | 1 |
Schistosoma mansoni | cathepsin C | 0.0292 | 0.1268 | 0.1268 |
Loa Loa (eye worm) | fibroinase | 0.1338 | 0.6337 | 0.6337 |
Plasmodium vivax | unspecified product | 0.0716 | 0.3323 | 0.5228 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0716 | 0.3323 | 0.3309 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Leishmania major | cathepsin L-like protease | 0.1338 | 0.6337 | 1 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0292 | 0.1268 | 0.1705 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Echinococcus granulosus | cathepsin L | 0.0292 | 0.1268 | 0.1268 |
Loa Loa (eye worm) | hypothetical protein | 0.0914 | 0.4282 | 0.4282 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Loa Loa (eye worm) | hypothetical protein | 0.0292 | 0.1268 | 0.1268 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0021 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0173 | 0.0173 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0085 | 0.0085 |
Entamoeba histolytica | cysteine protease, putative | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Brugia malayi | Cathepsin L-like precursor | 0.1338 | 0.6337 | 0.6337 |
Mycobacterium ulcerans | glutaminase | 0.027 | 0.1158 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0248 | 0.1056 | 0.1056 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Toxoplasma gondii | cathepsin B | 0.0849 | 0.3969 | 0.625 |
Leishmania major | cathepsin L-like protease | 0.1338 | 0.6337 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1338 | 0.6337 | 0.6337 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1338 | 0.6337 | 0.6337 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2093 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2093 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0048 | 0.0082 | 0.0082 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0849 | 0.3969 | 0.3969 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0085 | 0.0085 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2093 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0292 | 0.1268 | 0.1268 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.0097 | 0.0097 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0292 | 0.1268 | 0.1268 |
Onchocerca volvulus | 0.0292 | 0.1268 | 0.1974 | |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0716 | 0.3323 | 0.3309 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1338 | 0.6337 | 0.6337 |
Onchocerca volvulus | Cathepsin L homolog | 0.1338 | 0.6337 | 1 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0077 | 0.0226 | 0.0226 |
Brugia malayi | hypothetical protein | 0.0249 | 0.106 | 0.106 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0292 | 0.1268 | 0.1974 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0226 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0035 | 0.0035 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0021 | 0.0021 |
Leishmania major | cathepsin L-like protease | 0.1338 | 0.6337 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1338 | 0.6337 | 0.6337 |
Brugia malayi | Cathepsin L-like precursor | 0.1338 | 0.6337 | 0.6337 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0292 | 0.1268 | 0.1705 |
Loa Loa (eye worm) | hypothetical protein | 0.0914 | 0.4282 | 0.4282 |
Loa Loa (eye worm) | ctsf protein | 0.1338 | 0.6337 | 0.6337 |
Schistosoma mansoni | survival motor neuron protein | 0.0051 | 0.0097 | 0.0097 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1338 | 0.6337 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0292 | 0.1268 | 0.1268 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0097 | 0.0323 | 0.0323 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0077 | 0.0226 | 0.0226 |
Schistosoma mansoni | glutaminase | 0.027 | 0.1158 | 0.1158 |
Leishmania major | cathepsin L-like protease | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0051 | 0.0097 | 0.0097 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Echinococcus granulosus | cysteine protease | 0.0716 | 0.3323 | 0.3323 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0085 | 0.0085 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0716 | 0.3323 | 0.3323 |
Loa Loa (eye worm) | hypothetical protein | 0.0914 | 0.4282 | 0.4282 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0716 | 0.3323 | 0.5228 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0716 | 0.3323 | 0.5228 |
Entamoeba histolytica | cysteine protease, putative | 0.0292 | 0.1268 | 0.1957 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0292 | 0.1268 | 0.1705 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0292 | 0.1268 | 0.1974 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1338 | 0.6337 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Toxoplasma gondii | cathepsin CPC1 | 0.0292 | 0.1268 | 0.1974 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0226 | 0.1803 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0292 | 0.1268 | 0.1974 |
Loa Loa (eye worm) | glutaminase 2 | 0.027 | 0.1158 | 0.1158 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0292 | 0.1268 | 0.1974 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0716 | 0.3323 | 0.3323 |
Echinococcus multilocularis | cathepsin b | 0.2093 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0849 | 0.3969 | 0.3956 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1338 | 0.6337 | 0.6329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0914 | 0.4282 | 0.6746 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1338 | 0.6337 | 0.6329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 0.106 | 0.106 |
Onchocerca volvulus | 0.1338 | 0.6337 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.1338 | 0.6337 | 0.6337 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.1056 | 0.1056 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0292 | 0.1268 | 0.1974 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0716 | 0.3323 | 0.3323 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0292 | 0.1268 | 0.1974 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0048 | 0.0082 | 0.0082 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1338 | 0.6337 | 0.6337 |
Entamoeba histolytica | cysteine protease, putative | 0.0292 | 0.1268 | 0.1957 |
Entamoeba histolytica | cysteine protease, putative | 0.0292 | 0.1268 | 0.1957 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0021 | 0.0021 |
Onchocerca volvulus | 0.1338 | 0.6337 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0097 | 0.0323 | 0.0323 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0021 | 0.0021 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0579 | 0.2658 | 0.2658 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0077 | 0.0226 | 0.0226 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0292 | 0.1268 | 0.1974 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1338 | 0.6337 | 0.6337 |
Onchocerca volvulus | 0.1338 | 0.6337 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0914 | 0.4282 | 0.6739 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0292 | 0.1268 | 0.1974 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0021 | 0.0021 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Leishmania major | cathepsin L-like protease | 0.1338 | 0.6337 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0849 | 0.3969 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0292 | 0.1268 | 0.1268 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0424 | 0.1906 | 0.1906 |
Echinococcus multilocularis | cathepsin b | 0.2093 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0424 | 0.1906 | 0.1906 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.0173 | 0.0173 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0579 | 0.2658 | 0.2658 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0226 | 0.5 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0292 | 0.1268 | 0.1268 |
Echinococcus granulosus | cathepsin L | 0.0716 | 0.3323 | 0.3323 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0077 | 0.0226 | 0.0324 |
Brugia malayi | Cathepsin L-like precursor | 0.1338 | 0.6337 | 0.6337 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0226 | 0.5 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0249 | 0.106 | 0.106 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0051 | 0.0097 | 0.0823 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0849 | 0.3969 | 0.625 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0716 | 0.3323 | 0.3323 |
Giardia lamblia | Cathepsin B precursor | 0.0849 | 0.3969 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0021 | 0.0021 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0085 | 0.0085 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0051 | 0.0097 | 0.0823 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0021 | 0.0021 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0226 | 0.5 |
Trypanosoma cruzi | cysteine protease, putative | 0.0716 | 0.3323 | 0.3309 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0716 | 0.3323 | 0.5218 |
Entamoeba histolytica | hypothetical protein | 0.0292 | 0.1268 | 0.1957 |
Plasmodium vivax | unspecified product | 0.0424 | 0.1906 | 0.2984 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0716 | 0.3323 | 0.5218 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0021 | 0.0021 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0077 | 0.0226 | 0.0324 |
Onchocerca volvulus | Cathepsin L homolog | 0.1338 | 0.6337 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0292 | 0.1268 | 0.1974 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0292 | 0.1268 | 0.1974 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0249 | 0.106 | 0.106 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0292 | 0.1268 | 0.1268 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0292 | 0.1268 | 0.1705 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Brugia malayi | Cathepsin L-like precursor | 0.0914 | 0.4282 | 0.4282 |
Giardia lamblia | Cathepsin B precursor | 0.0849 | 0.3969 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0035 | 0.0035 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1338 | 0.6337 | 0.6329 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0021 | 0.0021 |
Echinococcus multilocularis | cathepsin L | 0.0292 | 0.1268 | 0.1268 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2093 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2093 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0225 | 0.094 | 1 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0292 | 0.1268 | 0.1705 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0716 | 0.3323 | 0.3323 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.0097 | 0.0097 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.0097 | 0.369 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0021 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0333 | 0.1464 | 0.1464 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0914 | 0.4282 | 0.427 |
Leishmania major | cathepsin L-like protease | 0.1338 | 0.6337 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0716 | 0.3323 | 0.5228 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0292 | 0.1268 | 0.1705 |
Brugia malayi | Cathepsin L-like precursor | 0.1338 | 0.6337 | 0.6337 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0085 | 0.0085 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0021 | 0.0021 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0292 | 0.1268 | 0.1268 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Loa Loa (eye worm) | cathepsin B | 0.0849 | 0.3969 | 0.3969 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0849 | 0.3969 | 0.625 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0292 | 0.1268 | 0.1957 |
Brugia malayi | cathepsin L-like precursor | 0.0914 | 0.4282 | 0.4282 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0849 | 0.3969 | 0.625 |
Entamoeba histolytica | cysteine protease, putative | 0.0292 | 0.1268 | 0.1957 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0292 | 0.1268 | 0.1249 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0292 | 0.1268 | 0.1974 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0716 | 0.3323 | 0.5218 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.0226 | 0.1803 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0292 | 0.1268 | 0.1957 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0292 | 0.1268 | 0.1974 |
Plasmodium vivax | vivapain-2 | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0292 | 0.1268 | 0.1268 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1338 | 0.6337 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0728 | 0.3379 | 0.3379 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Toxoplasma gondii | cathepsin CPC2 | 0.0292 | 0.1268 | 0.1974 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0716 | 0.3323 | 0.3309 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0292 | 0.1268 | 0.1268 |
Plasmodium vivax | unspecified product | 0.0292 | 0.1268 | 0.1974 |
Loa Loa (eye worm) | hypothetical protein | 0.0424 | 0.1906 | 0.1906 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0424 | 0.1906 | 0.1906 |
Plasmodium vivax | vivapain-2 | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1338 | 0.6337 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.1338 | 0.6337 | 0.6337 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0021 | 0.0021 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0716 | 0.3323 | 0.5068 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Brugia malayi | fibroinase precursor | 0.0292 | 0.1268 | 0.1268 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0292 | 0.1268 | 0.1705 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0226 | 0.0226 |
Brugia malayi | Trypsin family protein | 0.0248 | 0.1056 | 0.1056 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1338 | 0.6337 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0914 | 0.4282 | 0.4282 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Onchocerca volvulus | 0.0248 | 0.1056 | 0.1638 | |
Toxoplasma gondii | cathepsin CPL | 0.1338 | 0.6337 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.1056 | 0.1056 |
Echinococcus multilocularis | cysteine protease | 0.1338 | 0.6337 | 0.6337 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0097 | 0.0323 | 0.0323 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0292 | 0.1268 | 0.1974 |
Brugia malayi | cathepsin L precursor | 0.0292 | 0.1268 | 0.1268 |
Echinococcus multilocularis | geminin | 0.0333 | 0.1464 | 0.1464 |
Plasmodium vivax | vivapain-3 | 0.0716 | 0.3323 | 0.5228 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0292 | 0.1268 | 0.1974 |
Schistosoma mansoni | hypothetical protein | 0.0333 | 0.1464 | 0.1464 |
Brugia malayi | glutaminase DH11.1 | 0.027 | 0.1158 | 0.1158 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0035 | 0.0035 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0716 | 0.3323 | 0.3309 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0914 | 0.4282 | 0.4282 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0292 | 0.1268 | 0.1705 |
Echinococcus multilocularis | cathepsin L | 0.0716 | 0.3323 | 0.3323 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0292 | 0.1268 | 0.1705 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1338 | 0.6337 | 0.6337 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0292 | 0.1268 | 0.1705 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1338 | 0.6337 | 0.6329 |
Entamoeba histolytica | cysteine protease, putative | 0.0292 | 0.1268 | 0.1957 |
Echinococcus granulosus | cathepsin l1 | 0.0914 | 0.4282 | 0.4282 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0173 | 0.0173 |
Brugia malayi | Cathepsin L-like precursor | 0.0424 | 0.1906 | 0.1906 |
Schistosoma mansoni | cathepsin s | 0.0424 | 0.1906 | 0.1906 |
Leishmania major | cathepsin L-like protease | 0.1338 | 0.6337 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1338 | 0.6337 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0716 | 0.3323 | 0.5218 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0716 | 0.3323 | 0.5228 |
Echinococcus granulosus | cathepsin b | 0.2093 | 1 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0728 | 0.3379 | 0.3379 |
Onchocerca volvulus | 0.1338 | 0.6337 | 1 | |
Echinococcus granulosus | geminin | 0.0333 | 0.1464 | 0.1464 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Brugia malayi | Probable ClpP-like protease | 0.0077 | 0.0226 | 0.0226 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1338 | 0.6337 | 0.6337 |
Entamoeba histolytica | cysteine protease, putative | 0.0292 | 0.1268 | 0.1957 |
Trichomonas vaginalis | glutaminase, putative | 0.027 | 0.1158 | 0.18 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0085 | 0.0085 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0292 | 0.1268 | 0.1705 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1338 | 0.6337 | 0.6337 |
Onchocerca volvulus | Cathepsin F homolog | 0.1338 | 0.6337 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0248 | 0.1056 | 0.1056 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0292 | 0.1268 | 0.1974 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0424 | 0.1906 | 0.1906 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0077 | 0.0226 | 0.0324 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0097 | 0.0097 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0914 | 0.4282 | 0.4282 |
Onchocerca volvulus | 0.1338 | 0.6337 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.1338 | 0.6337 | 0.6337 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0424 | 0.1906 | 0.1889 |
Loa Loa (eye worm) | hypothetical protein | 0.0292 | 0.1268 | 0.1268 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0292 | 0.1268 | 0.1268 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0292 | 0.1268 | 0.1249 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Plasmodium vivax | vivapain-1 | 0.0716 | 0.3323 | 0.5228 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0077 | 0.0226 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1338 | 0.6337 | 0.6337 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0323 | 0.0323 |
Entamoeba histolytica | cysteine protease, putative | 0.0716 | 0.3323 | 0.5218 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0085 | 0.0085 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0292 | 0.1268 | 0.1705 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Loa Loa (eye worm) | hypothetical protein | 0.1338 | 0.6337 | 0.6337 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1338 | 0.6337 | 0.6337 |
Loa Loa (eye worm) | hypothetical protein | 0.0292 | 0.1268 | 0.1268 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0085 | 0.0085 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.1338 | 0.6337 | 0.6337 |
Onchocerca volvulus | 0.1338 | 0.6337 | 1 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1338 | 0.6337 | 0.6329 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0728 | 0.3379 | 0.3379 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0292 | 0.1268 | 0.1268 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0716 | 0.3323 | 0.3323 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0914 | 0.4282 | 0.6746 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0021 | 0.0021 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0292 | 0.1268 | 0.1268 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0292 | 0.1268 | 0.1974 |
Loa Loa (eye worm) | glutaminase | 0.027 | 0.1158 | 0.1158 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1338 | 0.6337 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0292 | 0.1268 | 0.1268 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 2.5 ug ml-1 | Effective concentration to achieve 50% protection of MT-4 cells against the cytopathic effect of HIV-2 | ChEMBL. | 8246223 |
EC50 (functional) | = 6.5 ug ml-1 | Effective concentration to achieve 50% protection of MT-4 cells against the cytopathic effect of HIV-1 | ChEMBL. | 8246223 |
EC50 (functional) | = 20 ug ml-1 | Giant-cell formation between persistently HIV-1 infected HUT-78 cells and uninfected MOLT-4 cells | ChEMBL. | 8246223 |
EC50 (functional) | = 100 ug ml-1 | Giant-cell formation between persistently HIV-2 infected HUT-78 cells and uninfected MOLT-4 cells | ChEMBL. | 8246223 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.