Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0345 | 0.8243 | 0.8243 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1158 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1158 | 0.1158 |
Echinococcus multilocularis | neuroligin | 0.007 | 0.1158 | 0.1158 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.007 | 0.1158 | 0.1158 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.007 | 0.1158 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.007 | 0.1158 | 0.1158 |
Brugia malayi | Carboxylesterase family protein | 0.007 | 0.1158 | 0.1158 |
Onchocerca volvulus | 0.007 | 0.1158 | 0.5 | |
Onchocerca volvulus | 0.007 | 0.1158 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1158 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1158 | 0.1158 |
Loa Loa (eye worm) | carboxylesterase | 0.007 | 0.1158 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1158 | 0.1158 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.007 | 0.1158 | 0.1158 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.007 | 0.1158 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1158 | 0.1158 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.007 | 0.1158 | 0.1158 |
Onchocerca volvulus | 0.007 | 0.1158 | 0.5 | |
Schistosoma mansoni | gliotactin | 0.007 | 0.1158 | 0.1158 |
Brugia malayi | Carboxylesterase family protein | 0.007 | 0.1158 | 0.1158 |
Brugia malayi | hypothetical protein | 0.007 | 0.1158 | 0.1158 |
Loa Loa (eye worm) | carboxylesterase | 0.007 | 0.1158 | 0.1158 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.007 | 0.1158 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0345 | 0.8243 | 0.8243 |
Onchocerca volvulus | 0.007 | 0.1158 | 0.5 | |
Echinococcus granulosus | geminin | 0.0345 | 0.8243 | 0.8243 |
Brugia malayi | Carboxylesterase family protein | 0.0414 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.007 | 0.1158 | 0.1158 |
Echinococcus multilocularis | geminin | 0.0345 | 0.8243 | 0.8243 |
Schistosoma mansoni | acetylcholinesterase | 0.007 | 0.1158 | 0.1158 |
Echinococcus granulosus | neuroligin | 0.007 | 0.1158 | 0.1158 |
Onchocerca volvulus | 0.007 | 0.1158 | 0.5 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0414 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1158 | 0.1158 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.007 | 0.1158 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.007 | 0.1158 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0414 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0414 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.007 | 0.1158 | 0.1158 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.007 | 0.1158 | 0.1158 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.007 | 0.1158 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.007 | 0.1158 | 0.1158 |
Echinococcus granulosus | carboxylesterase 5A | 0.0414 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.007 | 0.1158 | 0.1158 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.007 | 0.1158 | 0.1158 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.007 | 0.1158 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0414 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.007 | 0.1158 | 0.1158 |
Echinococcus multilocularis | acetylcholinesterase | 0.0414 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0414 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0414 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0414 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.007 | 0.1158 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0414 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IZ (functional) | = 0 cm | Antimicrobial activity against Candida albicans RCMB 005003 at 1 mg/ml by agar diffusion technique | ChEMBL. | 20875694 |
IZ (functional) | = 0.1 cm | Antimicrobial activity against Candida albicans RCMB 005003 at 2.5 mg/ml by agar diffusion technique | ChEMBL. | 20875694 |
IZ (functional) | = 0.1 cm | Antimicrobial activity against Candida albicans RCMB 005003 by twofold serial dilution method | ChEMBL. | 20875694 |
IZ (functional) | = 0.1 cm | Antimicrobial activity against Escherichia coli RCMB 103001 at 1 mg/ml by agar diffusion technique | ChEMBL. | 20875694 |
IZ (functional) | = 0.1 cm | Antimicrobial activity against Escherichia coli RCMB 103001 at 2.5 mg/ml by agar diffusion technique | ChEMBL. | 20875694 |
IZ (functional) | = 0.1 cm | Antimicrobial activity against Escherichia coli RCMB 103001 by twofold serial dilution method | ChEMBL. | 20875694 |
MIC (functional) | = 250 ug ml-1 | Antimicrobial activity against Candida albicans RCMB 005003 by twofold serial dilution method | ChEMBL. | 20875694 |
MIC (functional) | = 250 ug ml-1 | Antimicrobial activity against Escherichia coli RCMB 103001 by twofold serial dilution method | ChEMBL. | 20875694 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.