Detailed information for compound 1465166

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 657.584 | Formula: C33H38Cl2N4O6
  • H donors: 3 H acceptors: 6 LogP: 3.08 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: CNC(=O)C[N+]12CC[N+](CC1)(CC2)Cc1ccc2c(c1)C(=O)c1c2cc(cc1)C1=C(C(=O)O)N2[C@H]([C@H]1C)[C@H](C2=O)[C@H](O)C.[Cl-].[Cl-]
  • InChi: 1S/C33H36N4O6.2ClH/c1-18-27(30(33(42)43)35-29(18)28(19(2)38)32(35)41)21-5-7-23-24(15-21)22-6-4-20(14-25(22)31(23)40)16-36-8-11-37(12-9-36,13-10-36)17-26(39)34-3;;/h4-7,14-15,18-19,28-29,38H,8-13,16-17H2,1-3H3;2*1H/t18-,19+,28+,29+,36?,37?;;/m0../s1
  • InChiKey: GKNFSLNGCPGPJM-YQVHCKJGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Staphylococcus aureus PBP2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans bifunctional penicillin-binding protein 1A/1B PonA1 Get druggable targets OG5_129763 All targets in OG5_129763
Neospora caninum hypothetical protein Get druggable targets OG5_129763 All targets in OG5_129763
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_129763 All targets in OG5_129763
Mycobacterium tuberculosis Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase Get druggable targets OG5_129763 All targets in OG5_129763
Mycobacterium leprae PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE Get druggable targets OG5_129763 All targets in OG5_129763
Treponema pallidum penicillin-binding protein (pbp-2) Get druggable targets OG5_129763 All targets in OG5_129763
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium leprae PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN PBP2   727 aa 593 aa 22.9 %
Mycobacterium ulcerans bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 PBP2   727 aa 587 aa 23.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.121 0.1706 0.6886
Schistosoma mansoni hypothetical protein 0.0175 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.0805 0.1124 0.2713
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0027 0.0109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0312 0.0417 0.1684
Schistosoma mansoni bromodomain containing protein 0.0066 0.0064 0.0064
Trypanosoma cruzi PAB1-binding protein , putative 0.0127 0.0152 0.0612
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0153 0.0188 0.0683
Onchocerca volvulus 0.0318 0.0426 0.1544
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0605 0.0838 0.3383
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Onchocerca volvulus 0.003 0.0012 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.0428 0.1729
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0181 0.0229 0.0229
Onchocerca volvulus Fxna peptidase homolog 0.0309 0.0413 0.1497
Brugia malayi ecdysteroid receptor 0.0554 0.0764 0.2769
Loa Loa (eye worm) hypothetical protein 0.0411 0.056 0.135
Onchocerca volvulus 0.0181 0.0229 0.0829
Schistosoma mansoni apoferritin-2 0.0026 0.0006 0.0006
Loa Loa (eye worm) nuclear hormone receptor 0.0261 0.0344 0.083
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0082 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.0298 0.0397 0.0397
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0029 0.0258
Mycobacterium leprae POSSIBLE PENICILLIN-BINDING LIPOPROTEIN 0.0057 0.0052 0.0768
Loa Loa (eye worm) hypothetical protein 0.006 0.0056 0.0134
Schistosoma mansoni biogenic amine (5HT) receptor 0.0181 0.0229 0.0229
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Brugia malayi Nuclear hormone receptor-like 1 0.0292 0.0389 0.141
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0075 0.0273
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0298 0.0398 0.0398
Echinococcus multilocularis muscleblind protein 1 0.0318 0.0426 0.0426
Schistosoma mansoni opsin-like receptor 0.0181 0.0229 0.0229
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0213 0.0275 0.0275
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0633 0.0878 0.2118
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0054 0.0047 0.0047
Brugia malayi nuclear receptor NHR-88 0.0261 0.0344 0.1247
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0054 0.0047 0.4037
Loa Loa (eye worm) hypothetical protein 0.0074 0.0075 0.0182
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0213 0.0275 0.2446
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Schistosoma mansoni acetylcholinesterase 0.0298 0.0398 0.0398
Schistosoma mansoni Fxna peptidase (M28 family) 0.0309 0.0413 0.0413
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0022 0.0052
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0142 0.0173 0.07
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0181 0.0229 0.0229
Mycobacterium tuberculosis Probable penicillin-binding protein PbpA 0.0057 0.0052 0.0711
Plasmodium vivax hypothetical protein, conserved 0.0082 0.0087 0.2595
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0054 0.0047 0.0113
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0554 0.0764 0.0764
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0054 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.0049 0.004 0.016
Schistosoma mansoni opsin-like receptor 0.0181 0.0229 0.0229
Leishmania major hypothetical protein, conserved 0.0074 0.0075 0.0608
Schistosoma mansoni amine GPCR 0.0181 0.0229 0.0229
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0001 0.0001
Trypanosoma brucei glutaminyl cyclase, putative 0.0309 0.0413 0.3674
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0006 0.0014
Echinococcus granulosus biogenic amine 5HT receptor 0.0309 0.0413 0.0413
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1143 0.161 0.5835
Echinococcus granulosus sodium channel protein 0.0038 0.0024 0.0024
Echinococcus multilocularis nmda type glutamate receptor 0.0053 0.0045 0.0045
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0044 0.0032 0.0032
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0022 0.0087
Toxoplasma gondii target of rapamycin (TOR), putative 0.0411 0.0559 1
Schistosoma mansoni pyruvate kinase 0.0037 0.0022 0.0022
Schistosoma mansoni ferritin 0.0026 0.0006 0.0006
Echinococcus granulosus g protein coupled receptor 0.0181 0.0229 0.0229
Schistosoma mansoni histamine h1 receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0554 0.0764 0.1843
Brugia malayi Carboxylesterase family protein 0.1766 0.2505 0.908
Trichomonas vaginalis esterase, putative 0.0074 0.0075 0.0304
Mycobacterium ulcerans bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 0.0243 0.0318 0.527
Onchocerca volvulus 0.0024 0.0004 0.0014
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0038 0.0024 0.0332
Loa Loa (eye worm) hypothetical protein 0.0292 0.0389 0.0939
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0082 0.0087 0.2595
Loa Loa (eye worm) hypothetical protein 0.0037 0.0022 0.0053
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0001 0.0001
Brugia malayi FXNA 0.0309 0.0413 0.1497
Loa Loa (eye worm) hypothetical protein 0.0037 0.0022 0.0053
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0047 0.017
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Loa Loa (eye worm) hypothetical protein 0.0298 0.0398 0.0959
Schistosoma mansoni hypothetical protein 0.0242 0.0316 0.0316
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0075 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0096 0.0388
Schistosoma mansoni sodium-dependent amino acid transporter 0.0054 0.0047 0.0047
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0022 0.0192
Schistosoma mansoni importin beta-1 0.0059 0.0054 0.0054
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0554 0.0764 0.0764
Mycobacterium tuberculosis Possible penicillin-binding lipoprotein 0.0057 0.0052 0.0711
Brugia malayi hypothetical protein 0.0082 0.0087 0.0315
Brugia malayi hypothetical protein 0.0181 0.0229 0.0829
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0027 0.0109
Entamoeba histolytica protein kinase rad3, putative 0.0142 0.0173 0.07
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0153 0.0188 0.0761
Schistosoma mansoni glutamate receptor NMDA 0.0022 0.0001 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0181 0.0229 0.0229
Brugia malayi RNA recognition motif domain containing protein 0.019 0.0242 0.0877
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Echinococcus granulosus tachykinin peptides receptor 99D 0.0493 0.0677 0.0677
Brugia malayi G-protein coupled receptor 0.0181 0.0229 0.0829
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0049 0.004 0.0567
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0559 0.2255
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0261 0.0344 0.1247
Onchocerca volvulus 0.0175 0.022 0.0798
Schistosoma mansoni myosin xvIII 0.0181 0.0229 0.0229
Trichomonas vaginalis CMGC family protein kinase 0.0241 0.0315 0.1273
Entamoeba histolytica protein kinase domain containing protein 0.0241 0.0315 0.1273
Echinococcus multilocularis acetylcholinesterase 0.1766 0.2505 0.2505
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0523 0.072 0.2907
Mycobacterium ulcerans penicillin-binding lipoprotein 0.0057 0.0052 0.0803
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.1747 0.2478 1
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0241 0.0315 0.2758
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0084 0.1343
Brugia malayi FAT domain containing protein 0.0071 0.0071 0.0256
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0181 0.0229 0.0829
Echinococcus granulosus somatostatin receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) phosphatidylinositol 3 0.0082 0.0087 0.021
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0082 0.0087 0.0087
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0255 0.0335 0.5995
Brugia malayi orphan nuclear receptor NR2E1 0.0261 0.0344 0.1247
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0731 0.1019 0.3692
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0028 0.0115
Loa Loa (eye worm) hypothetical protein 0.0554 0.0764 0.1843
Echinococcus granulosus biogenic amine 5HT receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0049 0.004 0.0096
Echinococcus granulosus 7TM GPCR rhodopsin 0.0181 0.0229 0.0229
Brugia malayi AMP-binding enzyme family protein 0.0049 0.004 0.0144
Loa Loa (eye worm) hypothetical protein 0.0309 0.0413 0.0997
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0554 0.0764 0.0764
Schistosoma mansoni nuclear hormone receptor 0.0554 0.0764 0.0764
Echinococcus granulosus neuropeptides capa receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0298 0.0398 0.0959
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0153 0.0188 0.1621
Schistosoma mansoni hypothetical protein 0.0085 0.0091 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0142 0.0173 0.07
Loa Loa (eye worm) hypothetical protein 0.0309 0.0413 0.0997
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0554 0.0764 0.1843
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0298 0.0398 0.6106
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0318 0.0426 0.0426
Schistosoma mansoni neuroligin 3 (S09 family) 0.0298 0.0398 0.0398
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0084 0.1499
Echinococcus multilocularis neuropeptides capa receptor 0.0181 0.0229 0.0229
Leishmania major phosphatidylinositol 4-kinase, putative 0.0082 0.0087 0.0712
Brugia malayi Serotonin receptor 0.0181 0.0229 0.0829
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0261 0.0344 0.0344
Brugia malayi Muscleblind-like protein 0.0318 0.0426 0.1543
Brugia malayi hypothetical protein 0.0181 0.0229 0.0829
Trichomonas vaginalis PIKK family atypical protein kinase 0.0436 0.0595 0.24
Schistosoma mansoni microtubule-associated protein tau 0.6987 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Loa Loa (eye worm) hypothetical protein 0.0122 0.0145 0.0349
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0255 0.0335 0.1352
Echinococcus granulosus L aminoadipate semialdehyde 0.0175 0.022 0.022
Echinococcus granulosus glutaminyl peptide cyclotransferase 0.1943 0.2759 0.2759
Echinococcus granulosus geminin 0.0542 0.0748 0.0748
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Schistosoma mansoni hypothetical protein 0.0633 0.0878 0.0878
Brugia malayi Importin beta-1 subunit 0.0059 0.0054 0.0197
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0038 0.0024 0.0295
Giardia lamblia Kinase, CMGC GSK 0.0241 0.0315 0.2622
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0009
Schistosoma mansoni hypothetical protein 0.0542 0.0748 0.0748
Loa Loa (eye worm) hypothetical protein 0.1143 0.161 0.3884
Loa Loa (eye worm) phosphatidylinositol 3 0.2909 0.4145 1
Echinococcus multilocularis conserved hypothetical protein 0.0728 0.1014 0.1014
Schistosoma mansoni apoptosis regulator bax 0.0175 0.0221 0.0221
Onchocerca volvulus 0.0452 0.0618 0.2241
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0038 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0464 0.0635 0.2563
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0027 0.0109
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Onchocerca volvulus Glutaminyl cyclase homolog 0.1943 0.2759 1
Mycobacterium ulcerans bacterioferritin BfrA 0.0026 0.0006 0.0038
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0261 0.0344 0.1247
Leishmania major pyruvate kinase 0.0037 0.0022 0.0126
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0125 0.0148 0.0148
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0554 0.0764 0.2769
Echinococcus multilocularis geminin 0.0542 0.0748 0.0748
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0181 0.0229 0.0229
Echinococcus granulosus pyruvate kinase 0.0037 0.0022 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.034 0.0457 0.1845
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0153 0.0188 0.0455
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Leishmania major C-8 sterol isomerase-like protein 0.0805 0.1124 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0554 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0075 0.0075
Trichomonas vaginalis Clan MH, family M28, aminopeptidase S-like metallopeptidase 0.0309 0.0413 0.1667
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0535 0.0737 0.0737
Brugia malayi Cytochrome P450 family protein 0.0027 0.0007 0.0027
Schistosoma mansoni hypothetical protein 0.0085 0.0091 0.0091
Plasmodium vivax amine transporter, putative 0.0054 0.0047 0.1394
Brugia malayi mbt repeat family protein 0.0048 0.0038 0.0136
Loa Loa (eye worm) transcription factor SMAD2 0.0235 0.0307 0.074
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0535 0.0737 0.2973
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0535 0.0737 0.0737
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0049 0.004 0.0711
Brugia malayi MH2 domain containing protein 0.0235 0.0307 0.1112
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0166 0.0166
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0024 0.0004 0.0004
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Onchocerca volvulus 0.0181 0.0229 0.0829
Brugia malayi Dopamine receptor protein 2 0.0181 0.0229 0.0829
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0181 0.0229 0.0829
Schistosoma mansoni glutaminyl cyclase (M28 family) 0.1943 0.2759 0.2759
Echinococcus granulosus Mastin 0.0024 0.0004 0.0004
Echinococcus multilocularis neuropeptide receptor A26 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0436 0.0595 0.24
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0027 0.0109
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0037 0.0037
Echinococcus granulosus fmrfamide receptor 0.0181 0.0229 0.0229
Schistosoma mansoni biogenic amine (5HT) receptor 0.0309 0.0413 0.0413
Brugia malayi hypothetical protein 0.0452 0.0618 0.2241
Trichomonas vaginalis conserved hypothetical protein 0.0309 0.0413 0.1667
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0071 0.0071 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Echinococcus granulosus glutamate NMDA receptor subunit 0.0125 0.0148 0.0148
Trichomonas vaginalis PIKK family atypical protein kinase 0.034 0.0457 0.1845
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.017 0.0688
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0229 0.0229
Echinococcus multilocularis zinc finger protein 0.0023 0.0002 0.0002
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Schistosoma mansoni ferritin light chain 0.0026 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0559 0.2255
Brugia malayi Tachykinin-like peptides receptor 99D 0.0181 0.0229 0.0829
Brugia malayi Nuclear hormone receptor-like 1 0.0554 0.0764 0.2769
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0229 0.0229
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0605 0.0838 0.3383
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0001 0.0001
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0181 0.0229 0.0229
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0261 0.0344 0.0344
Toxoplasma gondii peptidase, M28 family protein 0.0309 0.0413 0.7393
Schistosoma mansoni ferritin light chain 0.0026 0.0006 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0166 0.0166
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0029 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0275 0.111
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0309 0.0413 0.0413
Echinococcus multilocularis snurportin 1 0.0633 0.0878 0.0878
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0255 0.0335 0.1352
Echinococcus granulosus ecdysone induced protein 78C 0.0554 0.0764 0.0764
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0054 0.0483
Giardia lamblia GTOR 0.0535 0.0737 0.6124
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0037 0.0037
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0044 0.0032 0.0949
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0261 0.0344 0.0344
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0006 0.0023
Loa Loa (eye worm) G-protein coupled receptor 0.0181 0.0229 0.0552
Loa Loa (eye worm) trypsin family protein 0.0024 0.0004 0.0009
Schistosoma mansoni neuropeptide F-like receptor 0.0181 0.0229 0.0229
Mycobacterium ulcerans penicillin-binding membrane protein PbpB 0.0057 0.0052 0.0803
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0191 0.0244 0.0244
Echinococcus multilocularis microtubule associated protein 2 0.6987 1 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0024 0.0088
Brugia malayi AKH receptor 0.0181 0.0229 0.0829
Echinococcus granulosus sodium and chloride dependent glycine 0.0054 0.0047 0.0047
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0161 0.0201 0.0811
Schistosoma mansoni hypothetical protein 0.0047 0.0037 0.0037
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0605 0.0838 0.7455
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0071 0.0285
Brugia malayi Nuclear hormone receptor-like 1 0.0292 0.0389 0.141
Echinococcus granulosus sterol regulatory element binding protein 0.0088 0.0096 0.0096
Giardia lamblia Phosphatidylinositol 4-kinase 0.0082 0.0087 0.0723
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0206 0.0265 0.1069
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0181 0.0229 0.0552
Onchocerca volvulus 0.0298 0.0398 0.1441
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0044 0.0032 0.0264
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0181 0.0229 0.0229
Brugia malayi hypothetical protein 0.0181 0.0229 0.0829
Onchocerca volvulus 0.0309 0.0413 0.1497
Echinococcus granulosus Nuclear hormone receptor HR96 0.0261 0.0344 0.0344
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0034 0.0138
Onchocerca volvulus 0.033 0.0443 0.1605
Schistosoma mansoni chromobox protein 0.0068 0.0067 0.0067
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0054 0.0047 0.0047
Trypanosoma cruzi target of rapamycin kinase 3 0.0436 0.0595 0.2402
Loa Loa (eye worm) hypothetical protein 0.0175 0.0221 0.0532
Echinococcus granulosus expressed conserved protein 0.0194 0.0247 0.0247
Plasmodium vivax hypothetical protein 0.0082 0.0087 0.2595
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Schistosoma mansoni coup transcription factor 0.0554 0.0764 0.0764
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0038 0.0154
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Loa Loa (eye worm) leucyl aminopeptidase 0.0309 0.0413 0.0997
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0731 0.1019 0.2458
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0082 0.0087 0.1556
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0004 0.0004
Echinococcus granulosus Niemann Pick C1 protein 0.0206 0.0265 0.0265
Echinococcus multilocularis vesicular acetylcholine transporter 0.0731 0.1019 0.1019
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0075 0.0304
Loa Loa (eye worm) hypothetical protein 0.0298 0.0398 0.0959
Brugia malayi CHE-14 protein 0.0088 0.0096 0.0348
Mycobacterium ulcerans hypothetical protein 0.0309 0.0413 0.6876
Echinococcus multilocularis g protein coupled receptor 0.0181 0.0229 0.0229
Brugia malayi G-protein coupled receptor 0.0181 0.0229 0.0829
Echinococcus multilocularis sterol regulatory element binding protein 0.0088 0.0096 0.0096
Brugia malayi hypothetical protein 0.0181 0.0229 0.0829
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0559 0.2255
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0156 0.0193 0.2922
Echinococcus granulosus g protein coupled receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) steroid hormone receptor 0.1449 0.2049 0.4943
Loa Loa (eye worm) hypothetical protein 0.033 0.0443 0.1068
Echinococcus granulosus protein kinase shaggy 0.0241 0.0315 0.0315
Onchocerca volvulus 0.0074 0.0075 0.0273
Onchocerca volvulus 0.0181 0.0229 0.0829
Loa Loa (eye worm) hypothetical protein 0.0054 0.0047 0.0113
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0075 0.1201
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0082 0.0087 0.0351
Trichomonas vaginalis spcc417.12 protein, putative 0.0298 0.0398 0.1605
Schistosoma mansoni thyroid hormone receptor 0.0554 0.0764 0.0764
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0142 0.0173 0.1543
Brugia malayi follicle stimulating hormone receptor 0.0181 0.0229 0.0829
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0038 0.0038
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0223 0.0289 0.1168
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0075 0.1201
Brugia malayi hypothetical protein 0.0054 0.0047 0.0169
Giardia lamblia NADPH oxidoreductase, putative 0.0161 0.0201 0.167
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.0428 0.1729
Schistosoma mansoni cellular tumor antigen P53 0.0148 0.0181 0.0181
Schistosoma mansoni ferritin 0.0026 0.0006 0.0006
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0022 0.0078
Echinococcus granulosus tm gpcr rhodopsin 0.0181 0.0229 0.0229
Echinococcus granulosus nuclear receptor nhr 48 0.0261 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0318 0.0426 0.1027
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0153 0.0188 0.0761
Echinococcus granulosus sex peptide receptor 0.0181 0.0229 0.0229
Onchocerca volvulus 0.0049 0.004 0.0144
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0309 0.0413 0.0413
Echinococcus multilocularis neuropeptide Y receptor 0.0181 0.0229 0.0229
Mycobacterium tuberculosis Carboxylesterase LipT 0.0298 0.0398 0.6106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0312 0.0417 0.1681
Brugia malayi hypothetical protein 0.0181 0.0229 0.0829
Loa Loa (eye worm) G-protein coupled receptor 0.0181 0.0229 0.0552
Brugia malayi Cytochrome P450 family protein 0.0027 0.0007 0.0027
Loa Loa (eye worm) hypothetical protein 0.0074 0.0075 0.0182
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0056 0.0225
Onchocerca volvulus 0.0024 0.0004 0.0014
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0182 0.0661
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0022 0.0078
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0255 0.0335 0.2979
Mycobacterium leprae conserved hypothetical protein 0.0049 0.004 0.0567
Trichomonas vaginalis PIKK family atypical protein kinase 0.0436 0.0595 0.24
Echinococcus granulosus acetylcholinesterase 0.1766 0.2505 0.2505
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0554 0.0764 0.0764
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0255 0.0335 0.0335
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0038 0.0154
Onchocerca volvulus Huntingtin homolog 0.0122 0.0145 0.0524
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0181 0.0229 0.0552
Giardia lamblia Hypothetical protein 0.0082 0.0087 0.0723
Echinococcus multilocularis fmrfamide receptor 0.0181 0.0229 0.0229
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0535 0.0737 0.267
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0082 0.0087 0.0087
Echinococcus granulosus neuropeptide receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0048 0.0038 0.009
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Entamoeba histolytica hypothetical protein 0.1397 0.1975 0.7969
Schistosoma mansoni zinc finger protein 0.0261 0.0344 0.0344
Onchocerca volvulus Protein ultraspiracle homolog 0.0554 0.0764 0.2769
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0075 0.0075
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0037 0.0022 0.0066
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0075 0.0304
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0137 0.0166 0.2499
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0554 0.0764 0.2769
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0261 0.0344 0.083
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0213 0.0275 0.2396
Echinococcus granulosus neuropeptide receptor 0.0181 0.0229 0.0229
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0229 0.0229
Trypanosoma brucei cytochrome P450, putative 0.0027 0.0007 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0275 0.111
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0027 0.0109
Schistosoma mansoni neuropeptide receptor 0.0181 0.0229 0.0229
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0242 0.0316 0.1146
Loa Loa (eye worm) hypothetical protein 0.0099 0.0111 0.0267
Schistosoma mansoni nicalin (M28 family) 0.0309 0.0413 0.0413
Loa Loa (eye worm) TYRA-2 protein 0.0181 0.0229 0.0552
Brugia malayi hypothetical protein 0.0261 0.0344 0.1247
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1747 0.2478 0.8981
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0054 0.0047 0.0835
Schistosoma mansoni hypothetical protein 0.0181 0.0229 0.0229
Chlamydia trachomatis transglycolase/transpeptidase 0.0057 0.0052 0.4838
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0084 0.1343
Schistosoma mansoni hypothetical protein 0.0047 0.0037 0.0037
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0028 0.0103
Loa Loa (eye worm) neuropeptide F receptor 0.0181 0.0229 0.0552
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0137 0.0166 0.0601
Echinococcus granulosus serotonin receptor 0.0181 0.0229 0.0229
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.002 0.002
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0034 0.0138
Brugia malayi intracellular kinase 0.0241 0.0315 0.1143
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0535 0.0737 0.2973
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.004 0.0526
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0161 0.0201 0.0811
Loa Loa (eye worm) hypothetical protein 0.0318 0.0426 0.1027
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0535 0.0737 0.6553
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0241 0.0315 0.0315
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1727 0.2448 0.2448
Onchocerca volvulus 0.0054 0.0047 0.0169
Loa Loa (eye worm) hypothetical protein 0.0292 0.0389 0.0939
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0038 0.0024 0.0024
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0054 0.0047 0.0047
Echinococcus multilocularis protein kinase shaggy 0.0241 0.0315 0.0315
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0318 0.0426 0.1027
Echinococcus granulosus para nitrobenzyl esterase 0.0298 0.0398 0.0398
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0554 0.0764 0.2769
Schistosoma mansoni tar DNA-binding protein 0.019 0.0242 0.0242
Brugia malayi Nuclear hormone receptor E75 0.0261 0.0344 0.1247
Loa Loa (eye worm) hypothetical protein 0.1766 0.2505 0.6044
Trichomonas vaginalis CMGC family protein kinase 0.0241 0.0315 0.1273
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0241 0.0315 0.0315
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0241 0.0315 0.0315
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0082 0.0087 0.0087
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0007 0.0018
Loa Loa (eye worm) carboxylesterase 0.0298 0.0398 0.0959
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0175 0.0221 0.0221
Echinococcus granulosus neuropeptide Y receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Schistosoma mansoni hypothetical protein 0.0181 0.0229 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0098
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0037 0.0037
Schistosoma mansoni fkbp-rapamycin associated protein 0.0142 0.0173 0.0173
Echinococcus multilocularis ecdysone induced protein 78C 0.0554 0.0764 0.0764
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0275 0.111
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0009
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0535 0.0737 0.2973
Brugia malayi G protein-coupled receptor 0.0181 0.0229 0.0829
Echinococcus granulosus zinc finger protein 0.0023 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Echinococcus multilocularis sodium channel protein 0.0038 0.0024 0.0024
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0038 0.0024 0.0149
Onchocerca volvulus 0.0298 0.0398 0.1441
Mycobacterium tuberculosis Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase 0.0196 0.0251 0.3814
Echinococcus multilocularis glycoprotein Antigen 5 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0142 0.0173 0.0419
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0142 0.0173 0.07
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.0395 0.1592
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.1143 0.161 0.161
Echinococcus multilocularis chromobox protein 1 0.0068 0.0067 0.0067
Echinococcus multilocularis somatostatin receptor 0.0181 0.0229 0.0229
Treponema pallidum sodium- and chloride- dependent transporter 0.0318 0.0426 0.7079
Echinococcus multilocularis expressed protein 0.0026 0.0006 0.0006
Brugia malayi Peptidase family M28 containing protein 0.1943 0.2759 1
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Schistosoma mansoni P2X receptor subunit 0.007 0.007 0.007
Echinococcus granulosus chromobox protein 1 0.0068 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0853 0.1194 0.288
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0024 0.0004 0.0004
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0255 0.0335 0.0808
Onchocerca volvulus 0.0306 0.0408 0.1479
Leishmania major phosphatidylinositol 3-kinase, putative 0.0213 0.0275 0.2396
Loa Loa (eye worm) hypothetical protein 0.0088 0.0096 0.0232
Chlamydia trachomatis transglycolase/transpeptidase 0.0057 0.0052 0.4838
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0007 0.0018
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0209 0.0269 0.0269
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0309 0.0413 0.0413
Onchocerca volvulus Arrow homolog 0.003 0.0012 0.0043
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0255 0.0335 1
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0026 0.0767
Echinococcus multilocularis fmrfamide receptor 0.0181 0.0229 0.0229
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0805 0.1124 0.4075
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0183 0.0441
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0082 0.0087 0.2595
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0181 0.0229 0.0229
Echinococcus granulosus G protein coupled receptor 139 0.0181 0.0229 0.0229
Echinococcus granulosus acetylcholinesterase 0.1766 0.2505 0.2505
Brugia malayi hypothetical protein 0.0261 0.0344 0.1247
Giardia lamblia Pyruvate kinase 0.0037 0.0022 0.0179
Loa Loa (eye worm) hypothetical protein 0.0554 0.0764 0.1843
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0181 0.0229 0.0829
Echinococcus multilocularis allatostatin A receptor 0.0181 0.0229 0.0229
Echinococcus multilocularis p2X purinoceptor 4 0.007 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0309 0.0413 0.0413
Onchocerca volvulus 0.0181 0.0229 0.0829
Echinococcus multilocularis Mastin 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.003 0.0012 0.003
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0038 0.0038
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0255 0.0335 0.1352
Onchocerca volvulus 0.0241 0.0315 0.1143
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0153 0.0188 0.3373
Mycobacterium tuberculosis Conserved protein 0.0074 0.0075 0.1079
Onchocerca volvulus 0.0024 0.0004 0.0014
Echinococcus granulosus carboxylesterase 5A 0.1766 0.2505 0.2505
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0022 0.0298
Onchocerca volvulus 0.0181 0.0229 0.0829
Schistosoma mansoni alpha-1 adrenergic receptor 0.0181 0.0229 0.0229
Toxoplasma gondii hypothetical protein 0.0028 0.0009 0.0155
Treponema pallidum penicillin-binding protein (pbp-2) 0.0439 0.0599 1
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Mycobacterium ulcerans lipoprotein LpqF 0.0066 0.0064 0.1008
Schistosoma mansoni nuclear receptor 0.0261 0.0344 0.0344
Brugia malayi hypothetical protein 0.0127 0.0152 0.0549
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0054 0.0047 0.0835
Loa Loa (eye worm) hypothetical protein 0.033 0.0443 0.1068
Echinococcus multilocularis neuropeptide Y receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Echinococcus multilocularis G protein coupled receptor 139 0.0181 0.0229 0.0229
Leishmania major hypothetical protein, unknown function 0.0082 0.0087 0.0712
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0075 0.0075
Brugia malayi Trypsin family protein 0.033 0.0443 0.1605
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0075 0.067
Schistosoma mansoni nuclear hormone receptor 0.0261 0.0344 0.0344
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0181 0.0229 0.0229
Brugia malayi Carboxylesterase family protein 0.0298 0.0398 0.1441
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0044 0.0032 0.0949
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0075 0.0304
Onchocerca volvulus 0.0261 0.0344 0.1247
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0181 0.0229 0.0229
Echinococcus multilocularis Zinc finger, PHD finger 0.0255 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0108 0.0125 0.0301
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0022 0.0087
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0027 0.0109
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Echinococcus multilocularis neuropeptides capa receptor 0.0181 0.0229 0.0229
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0075 0.1079
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.004 0.0605
Trichomonas vaginalis PIKK family atypical protein kinase 0.0312 0.0417 0.1684
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0022 0.0087
Brugia malayi nicalin 0.0309 0.0413 0.1497
Onchocerca volvulus 0.0054 0.0047 0.0169
Schistosoma mansoni steroid hormone receptor ad4bp 0.0554 0.0764 0.0764
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.0428 0.1729
Schistosoma mansoni ferritin 0.0026 0.0006 0.0006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0554 0.0764 0.0764
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.1747 0.2478 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0554 0.0764 0.0764
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Brugia malayi AMP-binding enzyme family protein 0.0049 0.004 0.0144
Brugia malayi Melatonin receptor type 1A 0.0181 0.0229 0.0829
Mycobacterium ulcerans carboxylesterase, LipT 0.0298 0.0398 0.6616
Trichomonas vaginalis PIKK family atypical protein kinase 0.0082 0.0087 0.0351
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0049 0.004 0.0525
Brugia malayi hypothetical protein 0.0122 0.0145 0.0524
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1747 0.2478 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0181 0.0229 0.0229
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.004 0.029
Brugia malayi leucyl aminopeptidase 0.0309 0.0413 0.1497
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0022 0.0078
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0054 0.0971
Toxoplasma gondii LsmAD domain-containing protein 0.0127 0.0152 0.2712
Echinococcus granulosus glutamate receptor 2 0.0022 0.0001 0.0001
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0554 0.0764 0.1843
Schistosoma mansoni vesicular acetylcholine transporter 0.0731 0.1019 0.1019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0535 0.0737 0.2973
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0049 0.004 0.0603
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0292 0.0389 0.0389
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.002 0.002
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0255 0.0335 0.5995
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0255 0.0335 0.0335
Treponema pallidum fructose-bisphosphate aldolase 0.032 0.0428 0.7122
Loa Loa (eye worm) hypothetical protein 0.0074 0.0075 0.0182
Loa Loa (eye worm) runx1 0.0057 0.0051 0.0122
Echinococcus granulosus muscleblind protein 0.0318 0.0426 0.0426
Brugia malayi hypothetical protein 0.0292 0.0389 0.141
Loa Loa (eye worm) hypothetical protein 0.0082 0.0087 0.021
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0554 0.0764 0.2769
Loa Loa (eye worm) phosphatidylinositol 3 0.0082 0.0087 0.021
Echinococcus multilocularis protein patched 0.0088 0.0096 0.0096
Echinococcus granulosus allatostatin A receptor 0.0181 0.0229 0.0229
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0075 0.1079
Mycobacterium tuberculosis Probable lipoprotein aminopeptidase LpqL 0.0309 0.0413 0.6347
Echinococcus granulosus GTP binding nuclear protein Ran 0.0044 0.0032 0.0032
Onchocerca volvulus 0.0181 0.0229 0.0829
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0275 0.111
Echinococcus multilocularis FTZ F1 alpha 0.0554 0.0764 0.0764
Echinococcus granulosus X box binding protein 1 0.0298 0.0397 0.0397
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0554 0.0764 0.2769
Echinococcus multilocularis BC026374 protein (S09 family) 0.0298 0.0398 0.0398
Loa Loa (eye worm) hypothetical protein 0.0554 0.0764 0.1843
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0175 0.0221 0.08
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0181 0.0229 0.0229
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0022 0.0001 0.0001
Schistosoma mansoni BC026374 protein (S09 family) 0.0298 0.0398 0.0398
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0049 0.004 0.0603
Echinococcus granulosus 7tm_1 domain containing protein 0.0181 0.0229 0.0229
Loa Loa (eye worm) apoptosis regulator protein 0.0175 0.0221 0.0532
Brugia malayi hypothetical protein 0.0181 0.0229 0.0829
Onchocerca volvulus 0.0181 0.0229 0.0829
Brugia malayi Nuclear hormone receptor E75 0.0261 0.0344 0.1247
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0009 0.0043
Schistosoma mansoni biogenic amine receptor 0.0181 0.0229 0.0229
Echinococcus granulosus Niemann Pick C1 protein 0.0294 0.0392 0.0392
Loa Loa (eye worm) norepinephrine transporter 0.0318 0.0426 0.1027
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0009 0.0258
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0142 0.0173 0.0173
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Leishmania major hypothetical protein, conserved 0.0127 0.0152 0.129
Echinococcus granulosus GPCR family 2 0.0047 0.0037 0.0037
Loa Loa (eye worm) DR-78 0.0261 0.0344 0.083
Echinococcus granulosus hypothetical protein 0.0909 0.1274 0.1274
Echinococcus multilocularis nuclear receptor nhr 48 0.0261 0.0344 0.0344
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0082 0.0087 0.0351
Loa Loa (eye worm) hypothetical protein 0.0047 0.0037 0.0089
Loa Loa (eye worm) hypothetical protein 0.0173 0.0217 0.0525
Entamoeba histolytica protein kinase domain containing protein 0.0241 0.0315 0.1273
Schistosoma mansoni tar DNA-binding protein 0.019 0.0242 0.0242
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0059 0.0059
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0038 0.009
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0054 0.0047 0.0047
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0075 0.0075
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0082 0.0087 0.0351
Loa Loa (eye worm) acetyltransferase 0.0148 0.0182 0.044
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0047 0.0047
Brugia malayi Trypsin family protein 0.0024 0.0004 0.0014
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0054 0.0047 0.0047
Brugia malayi RE15519p 0.0181 0.0229 0.0829
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0554 0.0764 0.1843
Brugia malayi AMP-binding enzyme family protein 0.0049 0.004 0.0144
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0049 0.004 0.0711
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0038 0.0024 0.0295
Loa Loa (eye worm) hypothetical protein 0.008 0.0084 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0056 0.0225
Echinococcus multilocularis g protein coupled receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.1766 0.2505 0.6044
Entamoeba histolytica hypothetical protein 0.0223 0.0289 0.1168
Brugia malayi nuclear receptor NHR-67 0.0261 0.0344 0.1247
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0559 0.2255
Echinococcus multilocularis muscleblind protein 0.0318 0.0426 0.0426
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0554 0.0764 0.0764
Leishmania major hypothetical protein, conserved 0.0309 0.0413 0.3632
Echinococcus granulosus neuropeptides capa receptor 0.0181 0.0229 0.0229
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0071 0.0071 0.0071
Echinococcus multilocularis glutaminyl peptide cyclotransferase 0.1943 0.2759 0.2759
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0054 0.0047 0.0047
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0255 0.0335 0.1352
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0309 0.0413 0.0997
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0037 0.0133
Onchocerca volvulus 0.0148 0.0181 0.0657
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0181 0.0229 0.0229
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0298 0.0398 0.0398
Brugia malayi steroid hormone receptor 0.1449 0.2049 0.7426
Echinococcus granulosus chromobox protein 1 0.0068 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Brugia malayi beta-lactamase 0.0074 0.0075 0.0273
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0554 0.0764 0.2769
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0298 0.0398 0.6106
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0082 0.0087 0.0087
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0183 0.0662
Loa Loa (eye worm) hypothetical protein 0.003 0.0012 0.0028
Loa Loa (eye worm) hypothetical protein 0.0298 0.0398 0.0959
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0022 0.0078
Echinococcus granulosus dro:myosuppressin receptor 0.0181 0.0229 0.0229
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0142 0.0173 0.0173
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.0395 0.1592
Brugia malayi nuclear hormone receptor family member odr-7 0.0261 0.0344 0.1247
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.0428 0.1729
Brugia malayi Carboxylesterase family protein 0.0298 0.0398 0.1441
Plasmodium falciparum pyruvate kinase 0.0037 0.0022 0.0644
Brugia malayi PHD-finger family protein 0.0028 0.0009 0.0034
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0024 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0229 0.0229
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0029 0.0117
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0054 0.0047 0.0113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0554 0.0764 0.1843
Schistosoma mansoni neuropeptide F-like receptor 0.0181 0.0229 0.0229
Schistosoma mansoni growth hormone secretagogue receptor 0.0181 0.0229 0.0229
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0075 0.1079
Brugia malayi chromobox protein homolog 3 0.0038 0.0024 0.0088
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0181 0.0229 0.0229
Onchocerca volvulus Bile acid receptor homolog 0.0554 0.0764 0.2769
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0298 0.0398 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Loa Loa (eye worm) RNA binding protein 0.019 0.0242 0.0584
Schistosoma mansoni RAR-like nuclear receptor 0.0554 0.0764 0.0764
Trypanosoma brucei PAB1-binding protein , putative 0.0127 0.0152 0.1348
Echinococcus granulosus thyroid hormone receptor alpha 0.1156 0.1629 0.1629
Mycobacterium ulcerans hypothetical protein 0.0049 0.004 0.0605
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0067 0.0272
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0193 0.2919
Brugia malayi hypothetical protein 0.0173 0.0217 0.0788
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0554 0.0764 0.0764
Schistosoma mansoni hypothetical protein 0.0024 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0554 0.0764 0.2769
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0075 0.1079
Onchocerca volvulus 0.0082 0.0087 0.0315
Brugia malayi G protein-coupled receptor F59B2.13 0.0181 0.0229 0.0829
Echinococcus multilocularis tumor protein p63 0.101 0.1419 0.1419
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0296 0.0395 0.3509
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0022 0.0656
Brugia malayi Heterochromatin protein 1 0.0068 0.0067 0.0244
Trichomonas vaginalis PIKK family atypical protein kinase 0.0312 0.0417 0.1681
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0535 0.0737 0.2973
Schistosoma mansoni survival motor neuron protein 0.0242 0.0316 0.0316
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0067 0.0272
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.1747 0.2478 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0181 0.0229 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.004 0.0569
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0452 0.0618 0.1492
Loa Loa (eye worm) hypothetical protein 0.0452 0.0618 0.1492
Echinococcus granulosus g-protein coupled receptor 0.0181 0.0229 0.0229
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0034 0.0612
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0213 0.0275 0.0275
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0436 0.0595 0.5294
Schistosoma mansoni hypothetical protein 0.0542 0.0748 0.0748
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0142 0.0173 0.0173
Echinococcus granulosus p2X purinoceptor 4 0.007 0.007 0.007
Loa Loa (eye worm) MBCTL1 0.0054 0.0047 0.0113
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0554 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0037 0.0022 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0027 0.0109
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0054 0.0483
Trichomonas vaginalis PIKK family atypical protein kinase 0.0142 0.0173 0.07
Schistosoma mansoni sodium/chloride dependent transporter 0.0056 0.005 0.005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0082 0.0087 0.0315
Brugia malayi Pre-SET motif family protein 0.0853 0.1194 0.4327
Brugia malayi neuropeptide F receptor 0.0181 0.0229 0.0829
Loa Loa (eye worm) hypothetical protein 0.0054 0.0047 0.0113
Schistosoma mansoni amine GPCR 0.0181 0.0229 0.0229
Schistosoma mansoni glutaminyl-peptide cyclotransferase-related 0.0309 0.0413 0.0413
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0038 0.0038
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0309 0.0413 0.0997
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0181 0.0229 0.0552
Echinococcus multilocularis sodium and chloride dependent glycine 0.0054 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0292 0.0389 0.0939
Echinococcus multilocularis glutamate receptor 2 0.0022 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0057 0.0051 0.0051
Echinococcus granulosus serine protein kinase ATM 0.0142 0.0173 0.0173
Brugia malayi nuclear receptor NHR-88 0.0554 0.0764 0.2769
Brugia malayi Trypsin family protein 0.0024 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0001 0.0001
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0009 0.0258
Toxoplasma gondii hypothetical protein 0.0054 0.0047 0.0835
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0118 0.0138 0.0138
Echinococcus multilocularis chromobox protein 1 0.0068 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0261 0.0344 0.0344
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0181 0.0229 0.0229
Echinococcus granulosus FTZ F1 alpha 0.0554 0.0764 0.0764
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0044 0.0596
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0175 0.0221 0.0221
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0054 0.0047 0.0169
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0001 0.0001
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0255 0.0335 0.1352
Schistosoma mansoni P2X receptor subunit 0.007 0.007 0.007
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0054 0.0047 0.0047
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0139 0.0169 0.0169
Loa Loa (eye worm) phosphatidylinositol 3 0.0082 0.0087 0.021
Brugia malayi ORL1-like opioid receptor 0.0181 0.0229 0.0829
Loa Loa (eye worm) hypothetical protein 0.0071 0.0071 0.0171
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.017 0.1516
Loa Loa (eye worm) beta-lactamase 0.0074 0.0075 0.0182
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0805 0.1124 0.4537
Echinococcus granulosus Protein patched homolog 1 0.0088 0.0096 0.0096
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0213 0.0275 0.111
Trichomonas vaginalis PIKK family atypical protein kinase 0.0337 0.0453 0.1828
Echinococcus multilocularis g protein coupled receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Loa Loa (eye worm) hypothetical protein 0.0309 0.0413 0.0997
Entamoeba histolytica hypothetical protein 0.0223 0.0289 0.1168
Brugia malayi nuclear hormone receptor 0.0554 0.0764 0.2769
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0436 0.0595 0.5262
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0605 0.0838 0.3383
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0049 0.004 0.1186
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.004 0.029
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.008 0.0084 0.0084
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0057 0.0051 0.0051
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0022 0.0052
Onchocerca volvulus 0.0261 0.0344 0.1247
Echinococcus granulosus tm gpcr rhodopsin 0.2832 0.4035 0.4035
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0054 0.0047 0.0047
Onchocerca volvulus 0.0181 0.0229 0.0829
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0022 0.0052
Echinococcus granulosus ferritin 0.0026 0.0006 0.0006
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0054 0.0047 0.0169
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0535 0.0737 0.6553
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0554 0.0764 0.0764
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0181 0.0229 0.0229
Echinococcus multilocularis GPCR, family 2 0.0047 0.0037 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0554 0.0764 0.2769
Onchocerca volvulus 0.0024 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0038 0.0023 0.0056
Echinococcus granulosus pyruvate kinase 0.0037 0.0022 0.0022
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.004 0.0027 0.0109
Loa Loa (eye worm) hypothetical protein 0.003 0.0012 0.0028
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0054 0.0047 0.0835
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0241 0.0315 0.0761
Loa Loa (eye worm) CYP4Cod1 0.0027 0.0007 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0554 0.0764 0.2769
Loa Loa (eye worm) nuclear receptor NHR-67 0.0261 0.0344 0.083
Plasmodium vivax SET domain protein, putative 0.0122 0.0145 0.4324
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0255 0.0335 0.1214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0559 0.2255
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0156 0.0193 0.316
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0082 0.0087 0.0315
Mycobacterium ulcerans lipase LipD 0.0074 0.0075 0.1201
Echinococcus multilocularis L aminoadipate semialdehyde 0.0175 0.022 0.022
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0137 0.0166 0.04
Echinococcus granulosus neuropeptide FF receptor 2 0.0181 0.0229 0.0229
Echinococcus multilocularis carboxylesterase 5A 0.1766 0.2505 0.2505
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0082 0.0087 0.0351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0559 0.2255
Trichomonas vaginalis PIKK family atypical protein kinase 0.0312 0.0417 0.1684
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0175 0.0221 0.0221
Loa Loa (eye worm) hypothetical protein 0.1185 0.167 0.403
Brugia malayi hypothetical protein 0.0181 0.0229 0.0829
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0344 0.0463 0.0463
Onchocerca volvulus Huntingtin homolog 0.0122 0.0145 0.0524
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0554 0.0764 0.2769
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0082 0.0087 0.1556
Loa Loa (eye worm) hypothetical protein 0.0298 0.0398 0.0959
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0054 0.0047 0.0169
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0001 0.0001
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0605 0.0838 0.3383
Brugia malayi Serotonin receptor 0.0666 0.0925 0.3354
Chlamydia trachomatis glutamine binding protein 0.0038 0.0024 0.0329
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0022 0.0305
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0044 0.0044
Brugia malayi nuclear hormone receptor 0.0261 0.0344 0.1247
Echinococcus multilocularis serotonin transporter 0.0318 0.0426 0.0426
Trichomonas vaginalis PIKK family atypical protein kinase 0.0337 0.0453 0.1828
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0166 0.0166
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.004 0.0161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0312 0.0417 0.1681
Treponema pallidum penicillin-binding protein (pbp-3) 0.0057 0.0052 0.0768
Trichomonas vaginalis PIKK family atypical protein kinase 0.0535 0.0737 0.2973
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0181 0.0229 0.0229
Schistosoma mansoni thyroid hormone receptor 0.0554 0.0764 0.0764
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0024 0.0004 0.0004
Echinococcus granulosus glycoprotein Antigen 5 0.0024 0.0004 0.0004
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0022 0.0656
Echinococcus multilocularis pyruvate kinase 0.0029 0.0011 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0229 0.0229
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0554 0.0764 0.0764
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0292 0.0389 0.0389
Brugia malayi Cytochrome P450 family protein 0.0056 0.005 0.0181
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1747 0.2478 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.004 0.0526
Plasmodium vivax glycogen synthase kinase 3, putative 0.0241 0.0315 0.9418
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0255 0.0335 1
Loa Loa (eye worm) hypothetical protein 0.0175 0.022 0.0531
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0037 0.0037
Onchocerca volvulus 0.0181 0.0229 0.0829
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.0428 0.1729
Schistosoma mansoni hypothetical protein 0.0024 0.0004 0.0004
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0175 0.0221 0.0221
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0181 0.0229 0.0229
Echinococcus granulosus serotonin transporter 0.0318 0.0426 0.0426
Brugia malayi Trypsin family protein 0.0024 0.0004 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0309 0.0413 0.1667
Echinococcus granulosus nmda type glutamate receptor 0.0053 0.0045 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0493 0.0677 0.1632
Echinococcus granulosus neuroligin 0.0298 0.0398 0.0398
Schistosoma mansoni retinoic acid receptor RXR 0.0554 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0038 0.0038
Loa Loa (eye worm) acetylcholinesterase 1 0.1766 0.2505 0.6044
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0223 0.0289 0.0289
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Brugia malayi hypothetical protein 0.0024 0.0004 0.0014
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0181 0.0229 0.0829
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.004 0.029
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0181 0.0229 0.0229
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0054 0.0047 0.0169
Schistosoma mansoni zinc finger protein 0.0023 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Echinococcus granulosus neuropeptide s receptor 0.0181 0.0229 0.0229
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0084 1
Onchocerca volvulus 0.0181 0.0229 0.0829
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0054 0.0047 0.0047
Echinococcus multilocularis orexin receptor type 2 0.0181 0.0229 0.0229
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0181 0.0229 0.0229
Toxoplasma gondii ABC1 family protein 0.0074 0.0075 0.1348
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0255 0.0335 0.0335
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0142 0.0173 0.0629
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0044 0.0032 0.0077
Brugia malayi hypothetical protein 0.0181 0.0229 0.0829
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.004 0.0605
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0605 0.0838 0.3038
Leishmania major glutaminyl cyclase, putative 0.0309 0.0413 0.3632
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0605 0.0838 0.0838
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.0145 0.0145
Echinococcus multilocularis protein dispatched 1 0.0101 0.0114 0.0114
Mycobacterium ulcerans hypothetical protein 0.0153 0.0188 0.3102
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0082 0.0087 0.0087
Schistosoma mansoni nuclear receptor 0.0261 0.0344 0.0344
Brugia malayi TAR-binding protein 0.019 0.0242 0.0877
Mycobacterium tuberculosis Conserved protein 0.0074 0.0075 0.1079
Echinococcus granulosus BC026374 protein S09 family 0.0298 0.0398 0.0398
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.3259 0.4648 0.4648
Onchocerca volvulus 0.0181 0.0229 0.0829
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0241 0.0315 0.0761
Leishmania major phosphatidylinositol kinase, putative 0.0082 0.0087 0.0712
Brugia malayi photoreceptor-specific nuclear receptor 0.0554 0.0764 0.2769
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0229 0.0229
Schistosoma mansoni nuclear hormone receptor 0.0261 0.0344 0.0344
Brugia malayi conserved hypotetical protein 0.0261 0.0344 0.1247
Mycobacterium ulcerans penicillin-binding protein PbpA 0.0057 0.0052 0.0803
Brugia malayi vesicular acetylcholine transporter unc-17 0.0731 0.1019 0.3692
Brugia malayi hypothetical protein 0.0292 0.0389 0.141
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0027 0.0109
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0082 0.0087 0.0351
Echinococcus multilocularis Protein lozenge 0.0057 0.0051 0.0051
Schistosoma mansoni hypothetical protein 0.0082 0.0087 0.0087
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0049 0.004 0.433
Schistosoma mansoni hypothetical protein 0.0071 0.0071 0.0071
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0255 0.0335 0.1352
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Wolbachia endosymbiont of Brugia malayi cell division protein FtsI 0.0057 0.0052 0.5866
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0153 0.0188 0.0761
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.004 0.0605
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0134 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Leishmania major phosphatidylinositol 3-kinase, putative 0.0255 0.0335 0.2932
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.003 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0054 0.0047 0.0113
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0554 0.0764 0.0764
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0181 0.0229 0.0552
Schistosoma mansoni ran 0.0044 0.0032 0.0032
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0554 0.0764 0.0764
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Onchocerca volvulus 0.0024 0.0004 0.0014
Onchocerca volvulus 0.0181 0.0229 0.0829
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0082 0.0087 0.0351
Brugia malayi Niemann-Pick C1 protein precursor 0.0206 0.0265 0.096
Brugia malayi mbt repeat family protein 0.0048 0.0038 0.0136
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0024 0.0004 0.0014
Schistosoma mansoni hypothetical protein 0.0047 0.0037 0.0037
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0181 0.0229 0.0229
Echinococcus granulosus tumor protein p63 0.101 0.1419 0.1419
Loa Loa (eye worm) hypothetical protein 0.0074 0.0075 0.0182
Echinococcus multilocularis ferritin 0.0026 0.0006 0.0006
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0082 0.0087 0.1556
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0075 0.0304
Loa Loa (eye worm) hypothetical protein 0.0074 0.0075 0.0182
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0261 0.0344 0.0344
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0261 0.0344 0.0344
Schistosoma mansoni tar DNA-binding protein 0.019 0.0242 0.0242
Mycobacterium tuberculosis Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen 0.0243 0.0318 0.4857
Brugia malayi nuclear receptor RXR 0.0292 0.0389 0.141
Mycobacterium leprae Probable penicillin-binding protein PbpA 0.0057 0.0052 0.0768
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0053 0.0045 0.0045
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0433 0.059 0.4906
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0554 0.0764 0.2769
Giardia lamblia Kinase, CMGC GSK 0.0241 0.0315 0.2622
Plasmodium vivax ataxin-2 like protein, putative 0.0127 0.0152 0.4524
Mycobacterium leprae Probable lipase LipE 0.0074 0.0075 0.1167
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0022 0.0248
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0027 0.0007 0.006
Echinococcus granulosus orexin receptor type 2 0.0181 0.0229 0.0229
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0026 0.0104
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.005 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Echinococcus multilocularis survival motor neuron protein 1 0.1185 0.167 0.167
Loa Loa (eye worm) hypothetical protein 0.0292 0.0389 0.0939
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0792 0.1107 0.4466
Echinococcus granulosus tm gpcr rhodopsin 0.0181 0.0229 0.0229
Onchocerca volvulus 0.0298 0.0398 0.1441
Echinococcus granulosus enteropeptidase 0.0024 0.0004 0.0004
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.004 0.0569
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1766 0.2505 0.2505
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Schistosoma mansoni nuclear receptor nhr-48 0.0261 0.0344 0.0344
Brugia malayi larval opioid receptor 0.0181 0.0229 0.0829
Echinococcus multilocularis neuropeptide receptor 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0148 0.0181 0.0437
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0153 0.0188 0.0761
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0049 0.004 0.0096
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0175 0.0221 0.0221
Schistosoma mansoni amine GPCR 0.0181 0.0229 0.0229
Loa Loa (eye worm) neuropeptide F receptor 0.0181 0.0229 0.0552
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0191 0.0244 0.0244
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Plasmodium vivax hypothetical protein, conserved 0.0054 0.0047 0.1394
Echinococcus granulosus Nuclear hormone receptor HR96 0.0261 0.0344 0.0344
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0175 0.022 0.022
Onchocerca volvulus 0.0173 0.0217 0.0788
Echinococcus multilocularis sodium and chloride dependent glycine 0.0054 0.0047 0.0047
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0175 0.022 0.0798
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0066 0.0064 0.0973
Loa Loa (eye worm) carboxylesterase 0.1766 0.2505 0.6044
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Entamoeba histolytica Ran family GTPase 0.0044 0.0032 0.0128
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.003 0.0012 0.0028
Loa Loa (eye worm) hypothetical protein 0.0025 0.0006 0.0014
Loa Loa (eye worm) hypothetical protein 0.0045 0.0034 0.0083
Echinococcus granulosus p2X purinoceptor 4 0.007 0.007 0.007
Echinococcus multilocularis enteropeptidase 0.0024 0.0004 0.0004
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0213 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0605 0.0837 0.202
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0084 0.1499
Schistosoma mansoni apoferritin-2 0.0026 0.0006 0.0006
Plasmodium falciparum glycogen synthase kinase 3 0.0241 0.0315 0.9418
Onchocerca volvulus 0.0298 0.0398 0.1441
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Entamoeba histolytica hypothetical protein 0.0082 0.0087 0.0351
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0554 0.0764 0.0764
Plasmodium falciparum importin beta, putative 0.0059 0.0054 0.162
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0554 0.0764 0.0764
Trichomonas vaginalis conserved hypothetical protein 0.0439 0.0599 0.2417
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0038 0.0038
Loa Loa (eye worm) phosphatidylinositol 3 0.0213 0.0275 0.0664
Trypanosoma brucei C-8 sterol isomerase, putative 0.0805 0.1124 1
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0022 0.0386
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0054 0.0047 0.0047
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0137 0.0166 0.0166
Mycobacterium leprae PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN 0.0243 0.0318 0.5252
Echinococcus multilocularis neuropeptide FF receptor 2 0.0181 0.0229 0.0229
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.028 0.0371 0.3296
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0318 0.0426 0.1544
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0054 0.0047 0.0047
Echinococcus multilocularis serine protein kinase ATM 0.0142 0.0173 0.0173
Loa Loa (eye worm) phosphatidylinositol 3 0.0523 0.072 0.1738
Echinococcus granulosus histone lysine methyltransferase setb 0.0139 0.0169 0.0169
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0181 0.0229 0.0229
Entamoeba histolytica hypothetical protein 0.0223 0.0289 0.1168
Schistosoma mansoni amine GPCR 0.0181 0.0229 0.0229
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0054 0.0047 0.0047
Brugia malayi hypothetical protein 0.0298 0.0398 0.1441
Schistosoma mansoni chromobox protein 0.0068 0.0067 0.0067
Onchocerca volvulus 0.0181 0.0229 0.0829
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.004 0.0605
Brugia malayi nuclear receptor RXR 0.0261 0.0344 0.1247
Schistosoma mansoni ferritin 0.0026 0.0006 0.0006
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.1512 0.2139 0.7754
Leishmania major phosphopantetheinyl transferase-like protein 0.0049 0.004 0.0289
Schistosoma mansoni hypothetical protein 0.0293 0.039 0.039
Echinococcus multilocularis X box binding protein 1 0.0298 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0054 0.0047 0.0113
Onchocerca volvulus Fxna peptidase homolog 0.0309 0.0413 0.1497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0181 0.0228 0.0922
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0298 0.0398 0.0398
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.008 0.0084 0.2501
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0605 0.0838 0.3383
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0084 1
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0127 0.0152 0.0366
Loa Loa (eye worm) solute carrier family 6 member 4 0.0318 0.0426 0.1027
Echinococcus multilocularis expressed conserved protein 0.0194 0.0247 0.0247
Brugia malayi neuropeptide F receptor 0.0181 0.0229 0.0829
Leishmania major mitochondrial DNA polymerase beta 0.0296 0.0395 0.3466
Trichomonas vaginalis PIKK family atypical protein kinase 0.0082 0.0087 0.0351
Leishmania major importin beta-1 subunit, putative 0.0048 0.0038 0.0275
Echinococcus multilocularis neuroligin 0.0298 0.0398 0.0398
Echinococcus multilocularis tar DNA binding protein 0.019 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.1943 0.2759 0.6656
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0181 0.0229 0.0229
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0082 0.0087 0.2595
Brugia malayi Carboxylesterase family protein 0.1766 0.2505 0.908
Schistosoma mansoni patched 1 0.0088 0.0096 0.0096
Onchocerca volvulus 0.0134 0.0161 0.0583
Brugia malayi GnHR receptor homolog 0.0181 0.0229 0.0829
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0034 0.0034
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0066 0.0064 0.09
Echinococcus granulosus vesicular acetylcholine transporter 0.0731 0.1019 0.1019
Schistosoma mansoni sodium/chloride dependent transporter 0.0318 0.0426 0.0426
Schistosoma mansoni opsin-like receptor 0.0181 0.0229 0.0229
Trypanosoma cruzi PAB1-binding protein , putative 0.0127 0.0152 0.0612
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.0145 0.2592
Loa Loa (eye worm) phosphatidylinositol kinase 0.0082 0.0087 0.021
Schistosoma mansoni biogenic amine receptor 0.0181 0.0229 0.0229
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0082 0.0087 0.0087
Onchocerca volvulus 0.0054 0.0047 0.0169
Mycobacterium ulcerans bacterioferritin BfrB 0.0026 0.0006 0.0038
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.008 0.0084 0.131
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0057 0.0051 0.0051
Brugia malayi RNA binding protein 0.019 0.0242 0.0877
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0292 0.0389 0.0389
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0028 0.0115
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0019 0.0203
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.3259 0.4648 0.4648
Trypanosoma brucei beta lactamase 0.0066 0.0064 0.0568
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.1143 0.161 0.161
Echinococcus multilocularis dro:myosuppressin receptor 0.0181 0.0229 0.0229
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0044 0.0044
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.017 0.146
Echinococcus multilocularis Niemann Pick C1 protein 0.0206 0.0265 0.0265
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.008 0.0084 0.0084
Echinococcus granulosus neuropeptide Y receptor 0.0181 0.0229 0.0229
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0082 0.0087 0.0087
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0223 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0554 0.0764 0.1843
Trichomonas vaginalis PIKK family atypical protein kinase 0.0535 0.0737 0.2973
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0255 0.0335 0.1352
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0022 0.0192
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0019 0.0203
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0181 0.0229 0.0229
Echinococcus granulosus alpha 1A adrenergic receptor 0.0181 0.0229 0.0229
Brugia malayi ecdysone receptor 0.0261 0.0344 0.1247
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0044 0.0032 0.0283
Loa Loa (eye worm) hypothetical protein 0.0318 0.0426 0.1027
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.1397 0.1975 0.7969
Loa Loa (eye worm) hypothetical protein 0.0554 0.0764 0.1843
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0153 0.0188 0.3374
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0261 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0054 0.0047 0.0113
Schistosoma mansoni lozenge 0.0057 0.0051 0.0051
Echinococcus granulosus neuropeptide receptor A26 0.0181 0.0229 0.0229
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0213 0.0275 0.2446
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Loa Loa (eye worm) hypothetical protein 0.0059 0.0054 0.0131
Schistosoma mansoni glutamate receptor NMDA 0.0125 0.0148 0.0148
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0082 0.0087 0.0773
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0054 0.0047 0.0047
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0182 0.0182
Trichomonas vaginalis set domain proteins, putative 0.0971 0.1363 0.5501
Brugia malayi sulfakinin receptor protein 0.0181 0.0229 0.0829
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0213 0.0275 0.0997
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0143 0.0577
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0075 0.0304
Leishmania major pyruvate kinase 0.0037 0.0022 0.0126
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0044 0.0032 0.0569
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0493 0.0677 0.2452
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Schistosoma mansoni neuropeptide receptor 0.0181 0.0229 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.0428 0.1729
Loa Loa (eye worm) hypothetical protein 0.0292 0.0389 0.0939
Loa Loa (eye worm) hypothetical protein 0.0139 0.0169 0.0407
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0054 0.0054
Echinococcus granulosus tar DNA binding protein 0.019 0.0242 0.0242
Brugia malayi tailless protein 0.0261 0.0344 0.1247
Plasmodium falciparum ataxin-2 like protein, putative 0.0127 0.0152 0.4524
Leishmania major GTP-binding protein, putative 0.0044 0.0032 0.0218
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0102 0.0115 0.0115
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0082 0.0087 0.2595
Trypanosoma cruzi glutaminyl cyclase, putative 0.0309 0.0413 0.1667
Loa Loa (eye worm) hypothetical protein 0.0206 0.0265 0.0639
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0535 0.0737 0.653
Echinococcus multilocularis para nitrobenzyl esterase 0.0298 0.0398 0.0398
Schistosoma mansoni hypothetical protein 0.0181 0.0229 0.0229
Brugia malayi Probable ClpP-like protease 0.008 0.0084 0.0304
Loa Loa (eye worm) hypothetical protein 0.0037 0.0022 0.0053
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0009
Schistosoma mansoni transcription factor LCR-F1 0.0223 0.0289 0.0289
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0261 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.0038 0.0024 0.0059
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0054 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0027 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0139 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.0044 0.0032 0.0077
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0022 0.0644
Onchocerca volvulus 0.0082 0.0087 0.0315
Loa Loa (eye worm) hypothetical protein 0.0493 0.0677 0.1632
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0032 0.0128
Mycobacterium tuberculosis Conserved hypothetical protein 0.0082 0.0087 0.1261
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0034 0.102
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0019 0.0203
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0022 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0535 0.0737 0.0737
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0255 0.0335 0.0335
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0059 0.0059
Echinococcus granulosus p2X purinoceptor 4 0.007 0.007 0.007
Onchocerca volvulus Neuropeptide F receptor homolog 0.0181 0.0229 0.0829
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.004 0.0161
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Loa Loa (eye worm) serotonin transporter b 0.0318 0.0426 0.1027
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0082 0.0087 0.0315
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0049 0.004 0.2921
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0038 0.0024 0.0329
Echinococcus multilocularis G-protein coupled receptor, putative 0.0181 0.0229 0.0229
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0022 0.0078
Entamoeba histolytica hypothetical protein 0.0082 0.0087 0.0351
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0009 0.0043
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Loa Loa (eye worm) hypothetical protein 0.0309 0.0413 0.0997
Brugia malayi Trypsin-like protease protein 5 0.0024 0.0004 0.0014
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0022 0.0087
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0213 0.0275 0.111
Loa Loa (eye worm) hypothetical protein 0.0037 0.0022 0.0053
Schistosoma mansoni tar DNA-binding protein 0.019 0.0242 0.0242
Schistosoma mansoni sodium/chloride dependent transporter 0.0054 0.0047 0.0047
Mycobacterium leprae PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE 0.0439 0.0599 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0181 0.0229 0.0229
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0241 0.0315 0.5646
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0255 0.0335 0.0335
Schistosoma mansoni P2X receptor subunit 0.007 0.007 0.007
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0044 0.0032 0.0128
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0019 0.0203
Brugia malayi hypothetical protein 0.0181 0.0229 0.0829
Schistosoma mansoni peptidase Clp (S14 family) 0.008 0.0084 0.0084
Schistosoma mansoni hypothetical protein 0.0223 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0074 0.0075 0.0182
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0038 0.0136
Trichomonas vaginalis PIKK family atypical protein kinase 0.0411 0.0559 0.2255
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0181 0.0229 0.0229
Trichomonas vaginalis PIKK family atypical protein kinase 0.0142 0.0173 0.07
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0156 0.0193 0.3186
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0554 0.0764 0.1843
Toxoplasma gondii hypothetical protein 0.0054 0.0047 0.0835
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0252 0.0331 0.2941
Brugia malayi Steroid receptor seven-up type 2 0.0554 0.0764 0.2769
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0229 0.0229
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0082 0.0087 0.0351
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0292 0.0389 0.0939
Brugia malayi hypothetical protein 0.0181 0.0229 0.0829
Loa Loa (eye worm) hypothetical protein 0.0318 0.0426 0.1027
Echinococcus multilocularis sex peptide receptor 0.0181 0.0229 0.0229
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.1747 0.2478 1
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0007 0.003
Echinococcus multilocularis p2X purinoceptor 4 0.007 0.007 0.007
Schistosoma mansoni amine GPCR 0.0181 0.0229 0.0229
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0042 0.017
Trypanosoma cruzi cytochrome P450, putative 0.0027 0.0007 0.003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0004 0.0004
Plasmodium falciparum ataxin-2 like protein, putative 0.0127 0.0152 0.4524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0436 0.0595 0.24
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.0161 0.0201 0.0811
Loa Loa (eye worm) hypothetical protein 0.0554 0.0764 0.1843
Schistosoma mansoni pyruvate kinase 0.0037 0.0022 0.0022
Treponema pallidum penicillin-binding protein (pbp-1) 0.0057 0.0052 0.0768
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0142 0.0173 0.0629
Brugia malayi Carboxylesterase family protein 0.0298 0.0398 0.1441
Plasmodium falciparum transporter, putative 0.0054 0.0047 0.1394
Onchocerca volvulus 0.0074 0.0075 0.0273
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.004 0.0161
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0309 0.0413 0.0413
Echinococcus multilocularis g-protein coupled receptor 0.0181 0.0229 0.0229
Schistosoma mansoni gliotactin 0.0298 0.0398 0.0398
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.004 0.0605
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0554 0.0764 0.0764
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0554 0.0764 0.2769
Schistosoma mansoni cercarial elastase (S01 family) 0.0024 0.0004 0.0004
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0137 0.0166 0.273
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0166 0.0166
Onchocerca volvulus 0.0181 0.0229 0.0829
Brugia malayi beta-lactamase family protein 0.0074 0.0075 0.0273
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0554 0.0764 0.0764
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0298 0.0398 0.0398
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0605 0.0838 0.3383
Loa Loa (eye worm) hypothetical protein 0.0298 0.0398 0.0959
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.1665 0.236 0.9525
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0554 0.0764 0.0764
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0037 0.0133
Echinococcus multilocularis serotonin receptor 0.0309 0.0413 0.0413
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0075 0.2248
Loa Loa (eye worm) phosphatidylinositol 3 0.0535 0.0737 0.1778
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0535 0.0737 0.653
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0472 0.0647 1
Mycobacterium ulcerans hypothetical protein 0.0074 0.0075 0.1201
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.006 0.0056 0.0225
Echinococcus multilocularis pyruvate kinase 0.0037 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0054 0.0047 0.0113
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0115 0.0417
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Leishmania major hypothetical protein, conserved 0.0082 0.0087 0.0712
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0049 0.004 0.1186
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0008 0.0033
Echinococcus granulosus sodium and chloride dependent glycine 0.0054 0.0047 0.0047
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0173 0.0173
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0137 0.0166 0.0166
Giardia lamblia NADPH oxidoreductase, putative 0.0161 0.0201 0.167
Brugia malayi hypothetical protein 0.1185 0.167 0.6054
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.033 0.0443 0.0443
Echinococcus granulosus snurportin 1 0.0633 0.0878 0.0878
Mycobacterium ulcerans hypothetical protein 0.0156 0.0193 0.3182
Mycobacterium leprae conserved hypothetical protein 0.0082 0.0087 0.1363
Trichomonas vaginalis NAD(P)H dehydrogenase, putative 0.004 0.0027 0.0109
Echinococcus granulosus survival motor neuron protein 1 0.1185 0.167 0.167
Loa Loa (eye worm) hypothetical protein 0.0153 0.0188 0.0455
Trypanosoma cruzi glutaminyl cyclase, putative 0.0309 0.0413 0.1667
Loa Loa (eye worm) phosphatidylinositol 3 0.0082 0.0087 0.021
Brugia malayi Carboxylesterase family protein 0.0298 0.0398 0.1441
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0009
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0241 0.0315 0.1273
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Onchocerca volvulus 0.0554 0.0764 0.2769
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0047 0.0047
Trichomonas vaginalis ran, putative 0.0044 0.0032 0.0128
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Schistosoma mansoni tar DNA-binding protein 0.019 0.0242 0.0242
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2832 0.4035 0.4035
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0082 0.0087 0.0773
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0034 0.0612
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0493 0.0677 0.0677
Onchocerca volvulus 0.0074 0.0075 0.0273
Onchocerca volvulus Fxna peptidase homolog 0.0309 0.0413 0.1497
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0075 0.0182
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0554 0.0764 0.2769
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0554 0.0764 0.1843
Trichomonas vaginalis FMN-dependent NADH-azoreductase, putative 0.004 0.0027 0.0109
Loa Loa (eye worm) hypothetical protein 0.0102 0.0115 0.0278
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0022 0.0261
Mycobacterium tuberculosis Conserved protein 0.0074 0.0075 0.1079
Entamoeba histolytica hypothetical protein 0.0142 0.0173 0.07
Toxoplasma gondii FATC domain-containing protein 0.0142 0.0173 0.3105
Entamoeba histolytica hypothetical protein 0.0048 0.0038 0.0154
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.008 0.0084 0.2501
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0261 0.0344 0.0344
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0082 0.0087 0.2595
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0082 0.0087 0.0087
Leishmania major phosphatidylinositol kinase related protein, putative 0.0082 0.0087 0.0712
Brugia malayi Pre-SET motif family protein 0.0122 0.0145 0.0525
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0075 0.1079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0213 0.0275 0.111
Brugia malayi Bromodomain containing protein 0.0077 0.008 0.029
Schistosoma mansoni hypothetical protein 0.0047 0.0037 0.0037
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0067 0.0163
Schistosoma mansoni hypothetical protein 0.0085 0.0091 0.0091
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0292 0.0389 0.0389
Trypanosoma brucei protein kinase, putative 0.0241 0.0315 0.2806
Brugia malayi putative neuropeptide receptor NPR1 0.0181 0.0229 0.0829
Brugia malayi RNA, U transporter 1 0.0169 0.0211 0.0765
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0139 0.0169 0.0169
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0153 0.0188 0.1676
Plasmodium falciparum amino acid transporter, putative 0.0054 0.0047 0.1394
Entamoeba histolytica iron-sulfur flavoprotein, putative 0.004 0.0027 0.0109
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0859 0.1203 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0047 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.034 0.0457 0.1845
Schistosoma mansoni hypothetical protein 0.0085 0.0091 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Entamoeba histolytica hypothetical protein 0.0082 0.0087 0.0351
Loa Loa (eye worm) hypothetical protein 0.0069 0.0069 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0008 0.0033
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0493 0.0677 0.0677
Loa Loa (eye worm) MH2 domain-containing protein 0.0235 0.0307 0.074
Trichomonas vaginalis PIKK family atypical protein kinase 0.0436 0.0595 0.24
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0088 0.0096 0.0232
Echinococcus multilocularis serotonin receptor 0.0309 0.0413 0.0413
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0183 0.0662
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0181 0.0229 0.0229
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.0428 0.1729
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0026 0.0214
Giardia lamblia Fructose-bisphosphate aldolase 0.032 0.0428 0.3561
Brugia malayi Bromodomain containing protein 0.0041 0.0028 0.0103
Loa Loa (eye worm) carboxylesterase 0.0298 0.0398 0.0959
Loa Loa (eye worm) hypothetical protein 0.0024 0.0004 0.0009
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0153 0.0188 0.0761
Schistosoma mansoni hypothetical protein 0.0175 0.0221 0.0221
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0047 0.0047
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0298 0.0398 0.1605
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0082 0.0087 0.0351
Echinococcus multilocularis 0.0082 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0554 0.0764 0.1843
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Brugia malayi beta-lactamase family protein 0.0074 0.0075 0.0273
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0554 0.0764 0.2769
Mycobacterium ulcerans beta-lactamase 0.0074 0.0075 0.1201
Entamoeba histolytica protein kinase, putative 0.0241 0.0315 0.1273
Brugia malayi Dopamine receptor 0.0181 0.0229 0.0829
Schistosoma mansoni neuropeptide receptor 0.0181 0.0229 0.0229
Echinococcus multilocularis neuropeptide s receptor 0.0181 0.0229 0.0229
Schistosoma mansoni neuropeptide receptor 0.0181 0.0229 0.0229
Mycobacterium ulcerans lipoprotein aminopeptidase LpqL 0.0309 0.0413 0.6876
Echinococcus granulosus expressed protein 0.0026 0.0006 0.0006
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0044 0.0644
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0038 0.0154
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0181 0.0229 0.0552
Onchocerca volvulus 0.0242 0.0316 0.1146
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0029 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0309 0.0413 0.1667
Echinococcus granulosus rhodopsin orphan GPCR 0.0181 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0149 0.0183 0.0441
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.032 0.0428 0.1729
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0038 0.0154
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0142 0.0173 0.07
Loa Loa (eye worm) hypothetical protein 0.0037 0.0022 0.0052
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0082 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0049 0.004 0.0096
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0153 0.0188 0.0761
Echinococcus multilocularis p2X purinoceptor 4 0.007 0.007 0.007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0181 0.0229 0.0229
Onchocerca volvulus 0.0181 0.0229 0.0829
Loa Loa (eye worm) hypothetical protein 0.0122 0.0145 0.0349
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.008 0.0084 1
Plasmodium vivax importin-beta 2, putative 0.0059 0.0054 0.162
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0075 0.1079
Echinococcus multilocularis transmembrane protease serine 3 0.0024 0.0004 0.0004
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0255 0.0335 0.2932
Loa Loa (eye worm) hypothetical protein 0.0554 0.0764 0.1843
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0181 0.0229 0.0229
Entamoeba histolytica modulator of drug activity B homolog, putative 0.004 0.0027 0.0109
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0075 0.1167
Trypanosoma brucei hypothetical protein, conserved 0.0049 0.004 0.0353
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.004 0.0605
Mycobacterium tuberculosis Conserved protein 0.0309 0.0413 0.6347
Onchocerca volvulus 0.0048 0.0038 0.0136
Loa Loa (eye worm) hypothetical protein 0.0261 0.0344 0.083
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0047 0.0047
Entamoeba histolytica hypothetical protein 0.004 0.0027 0.0109
Schistosoma mansoni hypothetical protein 0.0181 0.0229 0.0229
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.032 0.0428 0.1729
Onchocerca volvulus 0.0181 0.0229 0.0829
Echinococcus multilocularis neuropeptide receptor 0.0181 0.0229 0.0229
Toxoplasma gondii hypothetical protein 0.0048 0.0038 0.0676
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.032 0.0428 0.1729
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0037 0.0089
Onchocerca volvulus 0.0298 0.0398 0.1441
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0181 0.0229 0.0829
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0024 0.0004 0.0004
Echinococcus multilocularis acetylcholinesterase 0.1766 0.2505 0.2505
Mycobacterium ulcerans bifunctional penicillin-binding protein 1A/1B PonA1 0.0439 0.0599 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0261 0.0344 0.1247
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0022 0.0001 0.0001
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0182 0.0182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0375 0.0508 0.205
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0137 0.0166 0.0166
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.019 0.0242 0.0584
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Loa Loa (eye worm) hypothetical protein 0.0054 0.0047 0.0113
Echinococcus granulosus peptide allatostatin:somatostatin 0.0181 0.0229 0.0229
Echinococcus multilocularis thyroid hormone receptor alpha 0.0554 0.0764 0.0764
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0075 0.1079
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0024 0.0098
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0047 0.0047
Schistosoma mansoni ran 0.0044 0.0032 0.0032
Trichomonas vaginalis ferritin, putative 0.0026 0.0006 0.0025
Loa Loa (eye worm) hypothetical protein 0.0298 0.0398 0.0959
Giardia lamblia NADPH oxidoreductase, putative 0.0161 0.0201 0.167
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0022 0.0241
Onchocerca volvulus 0.0181 0.0229 0.0829
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0201 0.0811
Echinococcus granulosus transmembrane protease serine 3 0.0024 0.0004 0.0004
Brugia malayi nuclear hormone receptor family member nhr-6 0.0261 0.0344 0.1247
Trichomonas vaginalis conserved hypothetical protein 0.0153 0.0188 0.0761
Trichomonas vaginalis PIKK family atypical protein kinase 0.0365 0.0493 0.199
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0038 0.0024 0.0273
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0075 0.0304
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0309 0.0413 0.0413
Brugia malayi putative neuropeptide receptor 0.0181 0.0229 0.0829
Echinococcus multilocularis pyruvate kinase 0.0037 0.0022 0.0022
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.3259 0.4648 0.4648
Schistosoma mansoni adenoreceptor 0.0181 0.0229 0.0229
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.121 0.1706 0.6886
Schistosoma mansoni P2X receptor subunit 0.007 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0175 0.0221 0.0221
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.004 0.0605
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0181 0.0229 0.0229
Brugia malayi hypothetical protein 0.0223 0.0289 0.1049
Trichomonas vaginalis modulator of drug activity B, putative 0.004 0.0027 0.0109
Loa Loa (eye worm) hypothetical protein 0.0181 0.0229 0.0552
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0044 0.0032 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0312 0.0417 0.1684
Schistosoma mansoni biogenic amine receptor 0.0181 0.0229 0.0229
Toxoplasma gondii hypothetical protein 0.0309 0.0413 0.7393
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.008 0.0084 0.131
Loa Loa (eye worm) TAR-binding protein 0.019 0.0242 0.0584
Loa Loa (eye worm) melatonin receptor type 1A 0.0181 0.0229 0.0552
Brugia malayi Dopamine receptor protein 1 0.0181 0.0229 0.0829
Echinococcus granulosus g protein coupled receptor 0.0181 0.0229 0.0229
Echinococcus multilocularis Niemann Pick C1 protein 0.0294 0.0392 0.0392
Echinococcus granulosus importin subunit beta 1 0.0059 0.0054 0.0054
Onchocerca volvulus 0.0971 0.1363 0.4941
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0044 0.0596

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.33 ug ml-1 Binding affinity against PBP2a receptor by competition analysis with [3H]-benzylpenicillin using cell membrane fractions from the MRSA COL strain. ChEMBL. 10576693

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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