Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0006 | 0.001 | 0.5 |
Brugia malayi | Smad1 | 0.0008 | 0.0118 | 0.0108 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.2234 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0556 | 0.1668 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0045 | 0.2224 | 0.2213 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0025 | 0.1078 | 0.581 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.003 | 0.1389 | 1 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0027 | 0.1167 | 0.8388 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0556 | 0.0547 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0019 | 0.0741 | 0.5299 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0118 | 0.0108 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0556 | 0.1668 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0014 | 0.0431 | 0.1287 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0219 | 0.0641 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0025 | 0.1078 | 0.6023 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0386 | 0.2732 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3283 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0118 | 0.033 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0008 | 0.01 | 0.0508 |
Echinococcus multilocularis | rap guanine nucleotide exchange factor 6 | 0.0006 | 0.0014 | 0.0015 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0037 | 0.1784 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0386 | 0.3673 |
Trypanosoma cruzi | guanine nucleotide releasing protein, putative | 0.0006 | 0.0014 | 0.0036 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0219 | 0.021 |
Trypanosoma cruzi | hypothetical protein | 0.0006 | 0.0014 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.1605 | 0.1597 |
Echinococcus multilocularis | Smad4 | 0.0008 | 0.0118 | 0.033 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0009 | 0.0161 | 0.0462 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0027 | 0.1167 | 0.6337 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0219 | 0.0641 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.2509 | 0.2502 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.0081 | 0.0659 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0556 | 0.0547 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0009 | 0.0161 | 0.0462 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0741 | 0.5299 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0118 | 0.0108 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0161 | 0.0462 |
Mycobacterium ulcerans | polyketide synthase | 0.0025 | 0.1078 | 0.6023 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0021 | 0.084 | 0.4398 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0161 | 0.0151 |
Brugia malayi | isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.0732 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0741 | 0.5299 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0556 | 0.0547 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0027 | 0.1167 | 0.6337 |
Loa Loa (eye worm) | fatty acid synthase | 0.0025 | 0.1059 | 0.1051 |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0118 | 0.033 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0161 | 0.0462 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0161 | 0.0151 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0006 | 0.0014 | 0.0005 |
Toxoplasma gondii | hypothetical protein | 0.0009 | 0.0161 | 0.1095 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0985 | 0.0976 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0014 | 0.0463 | 0.2593 |
Onchocerca volvulus | 0.0043 | 0.2135 | 0.2124 | |
Schistosoma mansoni | smad1 5 8 and | 0.0008 | 0.0118 | 0.033 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0161 | 0.0462 |
Mycobacterium ulcerans | thioesterase TesA | 0.0021 | 0.084 | 0.4682 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.003 | 0.1389 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.003 | 0.1389 | 1 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0019 | 0.0741 | 0.4152 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.5299 |
Schistosoma mansoni | dep domain containing protein | 0.0009 | 0.0161 | 0.0462 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0024 | 0.1035 | 0.5799 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0161 | 0.0462 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.3283 | 0.3276 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.1078 | 0.6023 |
Schistosoma mansoni | ras GTP exchange factor | 0.0006 | 0.0014 | 0.0015 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3283 | 1 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0006 | 0.0014 | 0.0015 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0027 | 0.1167 | 0.6541 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0431 | 0.1287 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.001 | 0.0219 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.003 | 0.1389 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0556 | 0.1668 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0161 | 0.0151 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.1027 | 1 |
Mycobacterium ulcerans | thioesterase | 0.0021 | 0.084 | 0.4682 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0181 | 1 | 1 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0008 | 0.0118 | 0.033 |
Loa Loa (eye worm) | acyl carrier protein | 0.0011 | 0.0308 | 0.0298 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0019 | 0.0741 | 0.5299 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0219 | 0.0641 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0017 | 0.0595 | 0.3299 |
Brugia malayi | RasGEF domain containing protein | 0.0006 | 0.0014 | 0.0005 |
Schistosoma mansoni | Smad4 | 0.0008 | 0.0118 | 0.033 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0019 | 0.0741 | 0.2234 |
Brugia malayi | hypothetical protein | 0.002 | 0.0773 | 0.0765 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0018 | 0.0667 | 0.4766 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.2234 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.2234 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0009 | 0.0161 | 0.0151 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.5299 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.1389 | 0.1381 |
Leishmania major | hypothetical protein, conserved | 0.0008 | 0.0081 | 0.052 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0161 | 0.0462 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0009 | 0.0161 | 0.0146 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0219 | 0.0641 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0008 | 0.0081 | 0.0072 |
Loa Loa (eye worm) | Smad1 | 0.0008 | 0.0118 | 0.0108 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0009 | 0.0142 | 0.0795 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0161 | 0.0462 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0025 | 0.1078 | 0.107 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0161 | 0.0462 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.3283 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0556 | 0.1668 |
Echinococcus granulosus | smad | 0.0008 | 0.0118 | 0.033 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0556 | 0.1668 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0006 | 0.0014 | 0.0015 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0008 | 0.0118 | 0.033 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0161 | 0.0151 |
Brugia malayi | Isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.0732 |
Entamoeba histolytica | recQ family helicase, putative | 0.0013 | 0.0386 | 1 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0386 | 0.2732 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.0738 | 0.2225 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0017 | 0.0595 | 0.2941 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.1605 | 0.1597 |
Schistosoma mansoni | methyltransferase-related | 0.0008 | 0.0081 | 0.0219 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0027 | 0.1167 | 0.6541 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0386 | 0.2732 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0027 | 0.1167 | 0.6522 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0006 | 0.0014 | 0.0005 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0008 | 0.0081 | 0.0455 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0014 | 0.0005 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0019 | 0.0741 | 0.5299 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.002 | 0.08 | 0.4155 |
Brugia malayi | RasGEF domain containing protein | 0.0006 | 0.0014 | 0.0005 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0027 | 0.1167 | 0.6522 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.1027 | 0.1019 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.1027 | 0.311 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.002 | 0.08 | 0.4452 |
Onchocerca volvulus | 0.0009 | 0.0161 | 0.0146 | |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0037 | 0.1784 | 1 |
Brugia malayi | RNA binding protein | 0.0064 | 0.3283 | 0.3276 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0556 | 0.1668 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0025 | 0.1078 | 0.581 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0161 | 0.0462 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0023 | 0.0985 | 0.0976 |
Brugia malayi | N-terminal motif family protein | 0.0006 | 0.0014 | 0.0005 |
Leishmania major | hypothetical protein, conserved | 0.003 | 0.1389 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.2049 | 0.2041 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0219 | 0.021 |
Mycobacterium tuberculosis | Conserved protein | 0.0008 | 0.0081 | 0.0455 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0006 | 0.0014 | 0.0005 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0025 | 0.1078 | 0.6044 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0161 | 0.0462 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.001 | 0.0219 | 0.1521 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0008 | 0.0118 | 0.033 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0008 | 0.0118 | 0.0108 |
Echinococcus multilocularis | son of sevenless 1 | 0.0006 | 0.0014 | 0.0015 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3283 | 1 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0006 | 0.001 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0556 | 0.1668 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0023 | 0.0985 | 0.5519 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.2234 |
Schistosoma mansoni | regulator of G protein signaling | 0.0009 | 0.0161 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0219 | 0.021 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.003 | 0.1389 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0219 | 0.1521 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0008 | 0.0118 | 0.0108 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0161 | 0.0151 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0008 | 0.009 | 0.0505 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0027 | 0.1167 | 0.6541 |
Echinococcus granulosus | son of sevenless 1 | 0.0006 | 0.0014 | 0.0015 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0027 | 0.1167 | 0.6337 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0556 | 0.1668 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.003 | 0.1389 | 1 |
Brugia malayi | MH2 domain containing protein | 0.012 | 0.6495 | 0.6492 |
Brugia malayi | DIX domain containing protein | 0.0009 | 0.0161 | 0.0151 |
Mycobacterium ulcerans | polyketide synthase | 0.0027 | 0.1167 | 0.6522 |
Brugia malayi | hypothetical protein | 0.003 | 0.1389 | 0.1381 |
Echinococcus granulosus | Protein son of sevenless | 0.0006 | 0.0014 | 0.0015 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0025 | 0.1078 | 0.6044 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.3283 | 0.3276 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0571 | 0.4067 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0556 | 0.1668 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.3283 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0556 | 0.1668 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.1027 | 0.1019 |
Echinococcus granulosus | rap guanine nucleotide exchange factor 6 | 0.0006 | 0.0014 | 0.0015 |
Brugia malayi | N-terminal motif family protein | 0.0006 | 0.0014 | 0.0005 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.3283 | 0.3276 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.001 | 0.0228 | 0.128 |
Echinococcus multilocularis | ras GTP exchange factor | 0.0006 | 0.0014 | 0.0015 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.002 | 0.0818 | 0.4587 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.1078 | 0.6023 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.1605 | 0.4874 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3283 | 1 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.002 | 0.08 | 0.4452 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0037 | 0.1784 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.6578 | 0.6575 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0219 | 0.1521 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0219 | 0.0641 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0013 | 0.0373 | 0.2631 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0017 | 0.0595 | 0.3299 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0025 | 0.1078 | 0.6044 |
Echinococcus multilocularis | rap guanine nucleotide exchange factor 1 | 0.0006 | 0.0014 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.2509 | 0.2502 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0016 | 0.0577 | 0.4113 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.003 | 0.1389 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.2509 | 0.2502 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0016 | 0.0582 | 0.4147 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0008 | 0.0118 | 0.033 |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0006 | 0.0014 | 0.0015 |
Echinococcus multilocularis | Protein son of sevenless | 0.0006 | 0.0014 | 0.0015 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0037 | 0.1784 | 1 |
Echinococcus granulosus | Smad4 | 0.0008 | 0.0118 | 0.033 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0014 | 0.0431 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0161 | 0.0151 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0047 | 0.2356 | 0.2349 |
Brugia malayi | MH1 domain containing protein | 0.0008 | 0.0118 | 0.0108 |
Echinococcus granulosus | ras GTP exchange factor | 0.0006 | 0.0014 | 0.0015 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0009 | 0.0161 | 0.0462 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0008 | 0.01 | 0.0558 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.1027 | 0.311 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0.0741 | 0.5299 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0008 | 0.009 | 0.0454 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0219 | 0.021 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0009 | 0.0161 | 0.0462 |
Echinococcus multilocularis | smad | 0.0008 | 0.0118 | 0.033 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0021 | 0.084 | 0.4711 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.2509 | 0.2502 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.2234 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0556 | 0.0547 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0451 | 0.0442 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0161 | 0.0462 |
Brugia malayi | AMP-binding enzyme family protein | 0.0008 | 0.009 | 0.0081 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.0732 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.1027 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0014 | 0.0005 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0018 | 0.0676 | 0.3791 |
Brugia malayi | MH2 domain containing protein | 0.0008 | 0.0118 | 0.0108 |
Echinococcus granulosus | rap guanine nucleotide exchange factor 1 | 0.0006 | 0.0014 | 0.0015 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0008 | 0.0118 | 0.033 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 0.6495 | 0.6492 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.3283 | 0.3276 |
Brugia malayi | RasGEF domain containing protein | 0.0006 | 0.0014 | 0.0005 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 0.6495 | 0.6492 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3283 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0161 | 0.0151 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.086 | 0.6166 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0009 | 0.0161 | 0.0151 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0019 | 0.0741 | 0.5299 |
Schistosoma mansoni | smad | 0.0008 | 0.0118 | 0.033 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0006 | 0.0014 | 0.0015 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.3283 | 0.3276 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0219 | 0.0641 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0009 | 0.0161 | 0.0151 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.1078 | 0.6023 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0019 | 0.0741 | 0.2234 |
Trypanosoma cruzi | hypothetical protein | 0.0006 | 0.0014 | 0.0036 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0024 | 0.1035 | 0.5799 |
Onchocerca volvulus | 0.0023 | 0.0985 | 0.0972 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.