Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.8465 | 0.8465 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.8465 | 0.8465 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.5336 | 0.5336 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.3257 | 0.3257 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.8465 | 0.8465 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0.0005 | 0.5 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0005 | 0.5 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.8465 | 0.8465 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0005 | 0.5 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.8465 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.8465 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.8465 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0071 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 1 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0071 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.3257 | 0.3257 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.5336 | 0.6304 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.6064 | 0.6064 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0071 | 1 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0005 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.5336 | 0.5336 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 1 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.5336 | 0.5336 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.3257 | 0.3848 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.6064 | 0.6064 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 1 | 0.5 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.5336 | 0.5336 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.8465 | 0.8465 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.5336 | 0.5336 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.8465 | 0.8465 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0005 | 0.5 |
Brugia malayi | RNA binding protein | 0.0063 | 0.8465 | 0.8465 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0005 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 1 | 1 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.5336 | 0.5336 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.8465 | 0.8465 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0005 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.6064 | 0.7163 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.8465 | 0.8465 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0005 | 0.0005 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.8465 | 0.8465 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0005 | 0.5 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0005 | 0.0005 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.5336 | 0.5336 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.6064 | 0.7163 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.5336 | 0.5336 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.