Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.4244 | 0.4244 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.4244 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 1 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0 | 0.5 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.7162 | 0.7162 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.4244 | 0.4244 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0 | 0.5 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0063 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.4244 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.4244 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.3844 | 0.3844 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.7162 | 0.7162 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.4244 | 0.4244 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.3844 | 0.3844 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0036 | 0.4244 | 0.4244 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0 | 0.5 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.7162 | 0.7162 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.7162 | 0.7162 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.4244 | 0.4244 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.3844 | 0.3844 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.4244 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.