Detailed information for compound 1467115

Basic information

Technical information
  • TDR Targets ID: 1467115
  • Name: (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11, 12,14,15,16-octahydrocyclopenta[a]phenanthren e-6,17-dione
  • MW: 284.35 | Formula: C18H20O3
  • H donors: 1 H acceptors: 3 LogP: 2.49 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc2c(c1)C(=O)C[C@@H]1[C@@H]2CC[C@]2([C@H]1CCC2=O)C
  • InChi: 1S/C18H20O3/c1-18-7-6-12-11-3-2-10(19)8-14(11)16(20)9-13(12)15(18)4-5-17(18)21/h2-3,8,12-13,15,19H,4-7,9H2,1H3/t12-,13-,15+,18+/m1/s1
  • InChiKey: JOVYPIGRPWIXHQ-ONUSSAAZSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-6,17-quinone
  • 1,3,5(10)-Estratrien-3-ol-6,17-dione
  • 6-Ketoestrone
  • K8750_SIGMA

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens hydroxysteroid (17-beta) dehydrogenase 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein hydroxysteroid (17-beta) dehydrogenase 1 328 aa 265 aa 27.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus serine protein kinase ATM 0.0028 0.0282 0.0272
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0091 0.1457 0.7605
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0091 0.1457 0.7605
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0091 0.1457 0.471
Mycobacterium tuberculosis Probable oxidoreductase 0.0091 0.1457 0.2684
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0152 0.259 1
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0091 0.1457 0.1338
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Chlamydia trachomatis thioredoxin reductase 0.0152 0.259 0.5
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0091 0.1457 0.5382
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Schistosoma mansoni steroid dehydrogenase 0.0091 0.1457 0.1338
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0449 0.044
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0091 0.1457 0.2684
Echinococcus granulosus hypothetical protein 0.0091 0.1457 0.1449
Brugia malayi TAR-binding protein 0.0139 0.2357 0.409
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0091 0.1457 0.5382
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.1457 0.7605
Schistosoma mansoni retinal dehydrogenase 0.0091 0.1457 0.1338
Echinococcus multilocularis lamin dm0 0.0029 0.0286 0.0276
Plasmodium falciparum steroid dehydrogenase, putative 0.0091 0.1457 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0091 0.1457 0.7605
Schistosoma mansoni steroid dehydrogenase 0.0091 0.1457 0.1338
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0113 0.1873 1
Echinococcus granulosus steroid dehydrogenase 0.0091 0.1457 0.1449
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.1873 0.7077
Onchocerca volvulus Sepiapterin reductase homolog 0.0091 0.1457 0.2161
Echinococcus granulosus retinol dehydrogenase 11 0.0091 0.1457 0.1449
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Loa Loa (eye worm) hypothetical protein 0.0037 0.0449 0.0787
Brugia malayi dehydrogenases, short chain protein 9 0.0091 0.1457 0.2504
Schistosoma mansoni lamin 0.0029 0.0286 0.015
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0091 0.1457 0.5382
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0091 0.1457 0.1449
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0091 0.1457 0.7605
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0091 0.1457 0.2684
Mycobacterium leprae PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE 0.0091 0.1457 0.471
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0021 0.0138 0.0128
Toxoplasma gondii zinc finger CDGSH-type domain-containing protein 0.003 0.0315 0.1022
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0091 0.1457 0.5382
Echinococcus multilocularis carbonyl reductase 1 0.0091 0.1457 0.1449
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0133 0.2244 0.2237
Brugia malayi Dehydrogenases, short chain protein 30 0.0091 0.1457 0.2504
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0091 0.1457 0.7605
Loa Loa (eye worm) hypothetical protein 0.0037 0.0449 0.0787
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0091 0.1457 0.471
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0238 0.4206 1
Schistosoma mansoni hypothetical protein 0.0529 0.9652 0.9647
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0091 0.1457 0.471
Schistosoma mansoni thyroid hormone receptor 0.0144 0.2444 0.2339
Echinococcus multilocularis carbonyl reductase 1 0.0091 0.1457 0.1449
Brugia malayi Protein kinase domain containing protein 0.0318 0.5706 1
Loa Loa (eye worm) oxidoreductase 0.0091 0.1457 0.2554
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Leishmania major short chain dehydrogenase-like protein 0.0091 0.1457 0.7605
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0091 0.1457 0.7605
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0113 0.1873 0.3282
Loa Loa (eye worm) oxidoreductase 0.0091 0.1457 0.2554
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0091 0.1457 0.2684
Echinococcus granulosus tar DNA binding protein 0.0139 0.2357 0.2349
Loa Loa (eye worm) hypothetical protein 0.0037 0.0449 0.0787
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0245 0.4337 0.7601
Leishmania major quinonoid dihydropteridine reductase 0.0091 0.1457 0.7605
Onchocerca volvulus 0.0091 0.1457 0.2161
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0954 0.2359
Echinococcus multilocularis thyroid hormone receptor alpha 0.0144 0.2444 0.2437
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0954 0.0828
Mycobacterium ulcerans ketoacyl reductase 0.0091 0.1457 0.471
Schistosoma mansoni tar DNA-binding protein 0.0139 0.2357 0.225
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Echinococcus granulosus retinol dehydrogenase 11 0.0091 0.1457 0.1449
Schistosoma mansoni steroid dehydrogenase 0.0091 0.1457 0.1338
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Echinococcus multilocularis muscleblind protein 0.017 0.2937 0.293
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0449 0.1175
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0152 0.259 1
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0091 0.1457 0.471
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Schistosoma mansoni intermediate filament proteins 0.0029 0.0286 0.015
Onchocerca volvulus 0.0091 0.1457 0.2161
Trypanosoma brucei short-chain dehydrogenase, putative 0.0091 0.1457 0.7605
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0091 0.1457 0.7605
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0091 0.1457 0.2504
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0091 0.1457 0.7605
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0449 0.127
Entamoeba histolytica short chain dehydrogenase family protein 0.0091 0.1457 0.5382
Mycobacterium tuberculosis Probable oxidoreductase 0.0091 0.1457 0.2684
Trichomonas vaginalis steroid dehydrogenase, putative 0.0091 0.1457 0.5382
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0449 0.127
Echinococcus multilocularis conserved hypothetical protein 0.0091 0.1457 0.1449
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0091 0.1457 0.2504
Echinococcus granulosus WW domain containing oxidoreductase 0.0091 0.1457 0.1449
Mycobacterium ulcerans oxidoreductase 0.0091 0.1457 0.471
Giardia lamblia Reductase, putative 0.0091 0.1457 0.5382
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Mycobacterium leprae Probable short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Schistosoma mansoni tar DNA-binding protein 0.0139 0.2357 0.225
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0133 0.2244 0.2237
Onchocerca volvulus 0.0091 0.1457 0.2161
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0449 0.127
Echinococcus multilocularis serine protein kinase ATM 0.0028 0.0282 0.0272
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0091 0.1457 0.5382
Brugia malayi beta-lactamase family protein 0.0037 0.0449 0.0725
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.1457 0.7605
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.1873 0.176
Brugia malayi beta-lactamase 0.0037 0.0449 0.0725
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0318 0.5706 1
Loa Loa (eye worm) RNA binding protein 0.0139 0.2357 0.413
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0954 0.2359
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0091 0.1457 0.7605
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Leishmania major quinonoid dihydropteridine reductase 0.0091 0.1457 0.7605
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.7605
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0091 0.1457 0.1449
Trypanosoma brucei protein kinase, putative 0.0113 0.1873 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0113 0.1873 1
Brugia malayi RNA recognition motif domain containing protein 0.0139 0.2357 0.409
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Schistosoma mansoni carbonyl reductase 0.0091 0.1457 0.1338
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0091 0.1457 0.2684
Echinococcus multilocularis steroid dehydrogenase 0.0091 0.1457 0.1449
Mycobacterium ulcerans dehydrogenase 0.0091 0.1457 0.471
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0091 0.1457 0.7605
Brugia malayi oxidoreductase 0.0091 0.1457 0.2504
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0091 0.1457 0.2161
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0449 0.1795
Loa Loa (eye worm) hypothetical protein 0.0037 0.0449 0.0787
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0091 0.1457 0.7605
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0091 0.1457 0.7605
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0286 0.0501
Schistosoma mansoni hypothetical protein 0.003 0.0315 0.018
Echinococcus granulosus carbonyl reductase 1 0.0091 0.1457 0.1449
Schistosoma mansoni carbonyl reductase 0.0091 0.1457 0.1338
Schistosoma mansoni serine/threonine protein kinase 0.0318 0.5706 0.5646
Mycobacterium ulcerans dehydrogenase/reductase 0.0091 0.1457 0.471
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Schistosoma mansoni steroid dehydrogenase 0.0091 0.1457 0.1338
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Brugia malayi Retinol dehydrogenase 12 0.0091 0.1457 0.2504
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0954 0.1344
Brugia malayi hypothetical protein 0.0091 0.1457 0.2504
Mycobacterium ulcerans ketoacyl reductase 0.0091 0.1457 0.471
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0091 0.1457 0.2684
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0954 0.4705
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0091 0.1457 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0091 0.1457 0.471
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Loa Loa (eye worm) hypothetical protein 0.017 0.2937 0.5147
Schistosoma mansoni carbonyl reductase 0.0091 0.1457 0.1338
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0091 0.1457 0.471
Onchocerca volvulus 0.0037 0.0449 0.0301
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0091 0.1457 0.7605
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0091 0.1457 0.7605
Echinococcus granulosus lamin 0.0029 0.0286 0.0276
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0152 0.259 0.5699
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.1873 0.7077
Schistosoma mansoni steroid dehydrogenase 0.0091 0.1457 0.1338
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0318 0.5706 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0449 0.044
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Loa Loa (eye worm) hypothetical protein 0.003 0.0315 0.0552
Entamoeba histolytica hypothetical protein 0.0028 0.0282 0.0587
Echinococcus multilocularis muscleblind protein 1 0.017 0.2937 0.293
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0091 0.1457 0.1449
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0091 0.1457 1
Echinococcus granulosus oxidoreductase 0.0091 0.1457 0.1449
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0091 0.1457 0.2554
Loa Loa (eye worm) oxidoreductase 0.0091 0.1457 0.2554
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0028 0.0282 0.083
Schistosoma mansoni hypothetical protein 0.0548 1 1
Mycobacterium ulcerans short-chain dehydrogenase 0.0091 0.1457 0.471
Schistosoma mansoni hypothetical protein 0.0133 0.2244 0.2136
Trichomonas vaginalis esterase, putative 0.0037 0.0449 0.127
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0449 0.127
Schistosoma mansoni steroid dehydrogenase 0.0091 0.1457 0.1338
Loa Loa (eye worm) hypothetical protein 0.0029 0.0286 0.0501
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0286 0.0437
Toxoplasma gondii oxidoreductase, putative 0.0091 0.1457 0.7605
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0091 0.1457 0.7605
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Schistosoma mansoni steroid dehydrogenase 0.0091 0.1457 0.1338
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0113 0.1873 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0091 0.1457 0.7605
Mycobacterium leprae Probable oxidoreductase 0.0091 0.1457 0.471
Brugia malayi follicle stimulating hormone receptor 0.0245 0.4337 0.7585
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0954 0.0945
Loa Loa (eye worm) TAR-binding protein 0.0139 0.2357 0.413
Toxoplasma gondii oxidoreductase, putative 0.0091 0.1457 0.7605
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0113 0.1873 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0138 0.0176
Echinococcus multilocularis retinol dehydrogenase 11 0.0091 0.1457 0.1449
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0091 0.1457 0.7605
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0091 0.1457 0.1338
Leishmania major hypothetical protein, conserved 0.0091 0.1457 0.7605
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Mycobacterium tuberculosis Probable oxidoreductase 0.0091 0.1457 0.2684
Echinococcus multilocularis musashi 0.0029 0.0286 0.0276
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0954 0.0945
Toxoplasma gondii zinc finger cdgsh type protein 0.003 0.0315 0.1022
Leishmania major oxidoreductase-like protein 0.0091 0.1457 0.7605
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Loa Loa (eye worm) hypothetical protein 0.0212 0.3722 0.6522
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0091 0.1457 0.5382
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0021 0.0138 0.0128
Loa Loa (eye worm) oxidoreductase 0.0091 0.1457 0.2554
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0152 0.259 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0091 0.1457 0.5382
Loa Loa (eye worm) hypothetical protein 0.0037 0.0449 0.0787
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0028 0.0282 0.043
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0212 0.3722 0.6499
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Leishmania major quinonoid dihydropteridine reductase 0.0091 0.1457 0.7605
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0091 0.1457 0.2684
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0091 0.1457 0.5382
Leishmania major short chain dehydrogenase, putative 0.0091 0.1457 0.7605
Loa Loa (eye worm) oxidoreductase 0.0091 0.1457 0.2554
Schistosoma mansoni hypothetical protein 0.0548 1 1
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0954 0.0828
Toxoplasma gondii carbonyl reductase 1, putative 0.0091 0.1457 0.7605
Echinococcus multilocularis carbonyl reductase 1 0.0091 0.1457 0.1449
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0138 0.0004
Leishmania major hypothetical protein, conserved 0.0091 0.1457 0.7605
Onchocerca volvulus 0.003 0.0315 0.0053
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0091 0.1457 0.7605
Loa Loa (eye worm) dehydrogenase 0.0091 0.1457 0.2554
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Leishmania major dehydrogenase-like protein 0.0091 0.1457 0.7605
Giardia lamblia Hypothetical protein 0.0091 0.1457 0.5382
Schistosoma mansoni lamin 0.0029 0.0286 0.015
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0152 0.259 1
Brugia malayi intermediate filament protein 0.0029 0.0286 0.0437
Echinococcus multilocularis transient receptor potential cation channel 0.0091 0.1457 0.1449
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0091 0.1457 0.5382
Brugia malayi RE40412p 0.003 0.0315 0.0488
Mycobacterium tuberculosis Probable oxidoreductase 0.0091 0.1457 0.2684
Loa Loa (eye worm) hypothetical protein 0.0024 0.0208 0.0364
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0028 0.0282 0.0146
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0091 0.1457 0.2504
Onchocerca volvulus 0.0091 0.1457 0.2161
Plasmodium vivax hypothetical protein, conserved 0.0091 0.1457 1
Loa Loa (eye worm) hypothetical protein 0.017 0.2937 0.5147
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Trypanosoma brucei short-chain dehydrogenase, putative 0.0091 0.1457 0.7605
Leishmania major short chain dehydrogenase/reductase, putative 0.0091 0.1457 0.7605
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0091 0.1457 0.2684
Echinococcus granulosus mitogen activated protein kinase 0.0113 0.1873 0.1865
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0091 0.1457 0.2684
Echinococcus granulosus mitogen activated protein kinase 3 0.0113 0.1873 0.1865
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.7605
Toxoplasma gondii PfMNL-2 CISD1 family iron-sulfur protein, putative 0.003 0.0315 0.1022
Loa Loa (eye worm) hypothetical protein 0.0037 0.0449 0.0787
Onchocerca volvulus 0.0091 0.1457 0.2161
Trypanosoma cruzi short chain dehydrogenase, putative 0.0091 0.1457 0.7605
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0091 0.1457 0.5382
Brugia malayi RE40412p 0.003 0.0315 0.0488
Brugia malayi dehydrogenases, short chain protein 2 0.0091 0.1457 0.2504
Schistosoma mansoni steroid dehydrogenase 0.0091 0.1457 0.1338
Treponema pallidum thioredoxin reductase (trxB) 0.0152 0.259 0.5
Leishmania major hypothetical protein, conserved 0.0091 0.1457 0.7605
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0091 0.1457 0.5382
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0091 0.1457 0.5382
Leishmania major hypothetical protein, conserved 0.0091 0.1457 0.7605
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0091 0.1457 0.1449
Echinococcus granulosus carbonyl reductase 1 0.0091 0.1457 0.1449
Echinococcus multilocularis mitogen activated protein kinase 3 0.0113 0.1873 0.1865
Leishmania major 3-keto-dihydrosphingosine reductase 0.0091 0.1457 0.7605
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0091 0.1457 0.5382
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0113 0.1873 1
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Leishmania major short chain dehydrogenase/reductase, putative 0.0091 0.1457 0.7605
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0152 0.259 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0091 0.1457 0.5382
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0152 0.259 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0091 0.1457 0.5382
Mycobacterium ulcerans ketoacyl reductase 0.0091 0.1457 0.471
Onchocerca volvulus 0.0037 0.0449 0.0301
Leishmania major hypothetical protein, conserved 0.0091 0.1457 0.7605
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.1873 0.7077
Mycobacterium tuberculosis Possible oxidoreductase 0.0091 0.1457 0.2684
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0021 0.0138 0.0176
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0021 0.0138 0.0128
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0091 0.1457 0.2684
Onchocerca volvulus 0.0091 0.1457 0.2161
Schistosoma mansoni steroid dehydrogenase 0.0091 0.1457 0.1338
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0138 0.0241
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0091 0.1457 0.5382
Echinococcus multilocularis geminin 0.0548 1 1
Onchocerca volvulus 0.0091 0.1457 0.2161
Echinococcus granulosus conserved hypothetical protein 0.003 0.0315 0.0305
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.7605
Echinococcus granulosus carbonyl reductase 1 0.0091 0.1457 0.1449
Brugia malayi beta-lactamase family protein 0.0037 0.0449 0.0725
Onchocerca volvulus 0.0091 0.1457 0.2161
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0091 0.1457 0.2684
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0091 0.1457 0.7605
Mycobacterium tuberculosis Probable oxidoreductase 0.0091 0.1457 0.2684
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.0499 0.9089 0.9088
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0113 0.1873 1
Echinococcus multilocularis oxidoreductase 0.0091 0.1457 0.1449
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Echinococcus multilocularis tar DNA binding protein 0.0139 0.2357 0.2349
Loa Loa (eye worm) oxidoreductase 0.0091 0.1457 0.2554
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.1457 0.7605
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0318 0.5706 1
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.1457 0.7605
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0091 0.1457 0.2684
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0091 0.1457 0.1449
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0113 0.1873 1
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0152 0.259 1
Leishmania major hypothetical protein, unknown function 0.003 0.0315 0.1022
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0318 0.5706 0.5702
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0038 0.0067
Mycobacterium ulcerans short-chain dehydrogenase 0.0091 0.1457 0.471
Brugia malayi Muscleblind-like protein 0.017 0.2937 0.5114
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Loa Loa (eye worm) beta-lactamase 0.0037 0.0449 0.0787
Mycobacterium tuberculosis Possible oxidoreductase 0.0091 0.1457 0.2684
Toxoplasma gondii FATC domain-containing protein 0.0028 0.0282 0.083
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Echinococcus multilocularis conserved hypothetical protein 0.003 0.0315 0.0305
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0091 0.1457 0.2161
Trypanosoma brucei short-chain dehydrogenase, putative 0.0091 0.1457 0.7605
Onchocerca volvulus 0.003 0.0315 0.0053
Toxoplasma gondii ABC1 family protein 0.0037 0.0449 0.1795
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0449 0.0316
Trypanosoma cruzi short chain dehydrogenase, putative 0.0091 0.1457 0.7605
Entamoeba histolytica hypothetical protein, conserved 0.0091 0.1457 0.5382
Loa Loa (eye worm) oxidoreductase 0.0091 0.1457 0.2554
Echinococcus granulosus carbonyl reductase 1 0.0091 0.1457 0.1449
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0091 0.1457 0.7605
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0091 0.1457 0.7605
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0113 0.1873 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0315 0.0552
Echinococcus multilocularis lamin 0.0029 0.0286 0.0276
Onchocerca volvulus 0.0091 0.1457 0.2161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0282 0.0587
Onchocerca volvulus 0.0091 0.1457 0.2161
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.7605
Leishmania major quinonoid dihydropteridine reductase 0.0091 0.1457 0.7605
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0091 0.1457 0.1449
Mycobacterium leprae ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE 0.0091 0.1457 0.471
Giardia lamblia Kinase, CMGC MAPK 0.0113 0.1873 0.7077
Echinococcus multilocularis carbonyl reductase 1 0.0091 0.1457 0.1449
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0449 0.127
Leishmania major quinonoid dihydropteridine reductase 0.0091 0.1457 0.7605
Leishmania major phosphatidylinositol kinase related protein, putative 0.0021 0.0138 0.0004
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Onchocerca volvulus 0.0037 0.0449 0.0301
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0091 0.1457 0.1449
Entamoeba histolytica hypothetical protein, conserved 0.0091 0.1457 0.5382
Leishmania major quinonoid dihydropteridine reductase 0.0091 0.1457 0.7605
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Loa Loa (eye worm) hypothetical protein 0.0014 0.001 0.0017
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0152 0.259 1
Schistosoma mansoni hypothetical protein 0.0054 0.0753 0.0624
Mycobacterium ulcerans short-chain dehydrogenase 0.0091 0.1457 0.471
Entamoeba histolytica thioredoxin reductase, putative 0.0152 0.259 1
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0091 0.1457 0.1449
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0091 0.1457 0.2684
Mycobacterium ulcerans short chain dehydrogenase 0.0091 0.1457 0.471
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0529 0.9652 0.9647
Mycobacterium ulcerans short-chain type oxidoreductase 0.0091 0.1457 0.471
Echinococcus granulosus hypothetical protein 0.0091 0.1457 0.1449
Leishmania major quinonoid dihydropteridine reductase 0.0091 0.1457 0.7605
Mycobacterium tuberculosis Probable oxidoreductase 0.0091 0.1457 0.2684
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0449 0.0725
Leishmania major hypothetical protein, conserved 0.0037 0.0449 0.1795
Entamoeba histolytica short chain dehydrogenase family protein 0.0091 0.1457 0.5382
Trypanosoma brucei short-chain dehydrogenase, putative 0.0091 0.1457 0.7605
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0091 0.1457 0.2684
Schistosoma mansoni thyroid hormone receptor 0.0144 0.2444 0.2339
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.1873 0.7077
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0091 0.1457 0.7605
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0449 0.0787
Leishmania major short chain dehydrogenase, putative 0.0091 0.1457 0.7605
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0954 0.2359
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.1457 0.7605
Echinococcus granulosus intermediate filament protein 0.0029 0.0286 0.0276
Schistosoma mansoni tar DNA-binding protein 0.0139 0.2357 0.225
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0091 0.1457 0.7605
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0091 0.1457 0.1338
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0091 0.1457 0.1338
Entamoeba histolytica hypothetical protein 0.0091 0.1457 0.5382
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.7605
Giardia lamblia Thioredoxin reductase 0.0152 0.259 1
Trypanosoma brucei oxidoreductase-like protein 0.0091 0.1457 0.7605
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0091 0.1457 0.2684
Brugia malayi RNA binding protein 0.0139 0.2357 0.409
Giardia lamblia Short-chain dehydrogenase, putative 0.0091 0.1457 0.5382
Loa Loa (eye worm) oxidoreductase 0.0091 0.1457 0.2554
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0286 0.0501
Schistosoma mansoni tar DNA-binding protein 0.0139 0.2357 0.225
Mycobacterium ulcerans oxidoreductase 0.0091 0.1457 0.471
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0091 0.1457 0.2684
Leishmania major pteridine reductase 1 0.0091 0.1457 0.7605
Echinococcus granulosus muscleblind protein 0.017 0.2937 0.293
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0091 0.1457 0.2684
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0091 0.1457 0.2161
Onchocerca volvulus 0.0091 0.1457 0.2161
Brugia malayi MAP kinase sur-1 0.0113 0.1873 0.3237
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0318 0.5706 0.5702
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0091 0.1457 0.2684
Echinococcus multilocularis mitogen activated protein kinase 0.0113 0.1873 0.1865
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0449 0.1795
Mycobacterium ulcerans carveol-like dehydrogenase 0.0091 0.1457 0.471
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0091 0.1457 0.471
Loa Loa (eye worm) phosphatidylinositol 3 0.0021 0.0138 0.0241
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0091 0.1457 0.1449
Schistosoma mansoni short chain dehydrogenase 0.0091 0.1457 0.1338
Brugia malayi hypothetical protein 0.0091 0.1457 0.2504
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0139 0.2357 0.413
Echinococcus multilocularis retinol dehydrogenase 13 0.0091 0.1457 0.1449
Onchocerca volvulus 0.0091 0.1457 0.2161
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.1457 0.7605
Schistosoma mansoni steroid dehydrogenase 0.0091 0.1457 0.1338
Loa Loa (eye worm) hypothetical protein 0.0091 0.1457 0.2554
Onchocerca volvulus 0.0212 0.3722 0.6339
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0449 0.0316
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.0499 0.9089 0.9088
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0028 0.0282 0.083
Plasmodium vivax steroid dehydrogenase, putative 0.0091 0.1457 1
Trypanosoma brucei short-chain dehydrogenase, putative 0.0091 0.1457 0.7605
Schistosoma mansoni tar DNA-binding protein 0.0139 0.2357 0.225
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0021 0.0138 0.0128
Loa Loa (eye worm) hypothetical protein 0.0028 0.0276 0.0484
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0091 0.1457 0.5382
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0954 0.4705
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0449 0.1795
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0091 0.1457 0.2504
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0091 0.1457 0.7605
Onchocerca volvulus 0.0091 0.1457 0.2161
Loa Loa (eye worm) dehydrogenase 0.0091 0.1457 0.2554
Mycobacterium tuberculosis Probable dehydrogenase 0.0091 0.1457 0.2684
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0318 0.5706 1
Echinococcus granulosus lamin dm0 0.0029 0.0286 0.0276
Loa Loa (eye worm) oxidoreductase 0.0091 0.1457 0.2554
Echinococcus multilocularis steroid dehydrogenase 0.0091 0.1457 0.1449
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0091 0.1457 0.2684
Echinococcus multilocularis retinol dehydrogenase 11 0.0091 0.1457 0.1449
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0208 0.0402
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0091 0.1457 0.2684
Brugia malayi Dehydrogenases, short chain protein 2 0.0091 0.1457 0.2504

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 0.34 uM Inhibition of 17beta HSD1 in T47D cells ChEMBL. 16480268
Inhibition (functional) < 10 % Inhibition of 17beta HSD2 in MDA-MB231cells at 10 uM ChEMBL. 16480268
Inhibition (functional) = 98 % Inhibition of 17beta HSD1 in T47D cells at 10 uM ChEMBL. 16480268

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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