Detailed information for compound 1467484

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 348.452 | Formula: C21H29FO3
  • H donors: 2 H acceptors: 2 LogP: 3.82 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: FCCOC[C@H]1C[C@]2(C)[C@@H](O)CC[C@H]2[C@H]2[C@H]1c1ccc(cc1CC2)O
  • InChi: 1S/C21H29FO3/c1-21-11-14(12-25-9-8-22)20-16-5-3-15(23)10-13(16)2-4-17(20)18(21)6-7-19(21)24/h3,5,10,14,17-20,23-24H,2,4,6-9,11-12H2,1H3/t14-,17+,18+,19+,20-,21+/m1/s1
  • InChiKey: ULKAKSLHGGBYHL-CBQIQWOPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0033 0.006
Echinococcus granulosus Tubulin beta 2C chain 0.0234 0.5538 0.5537
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0122 0.2781 0.5019
Loa Loa (eye worm) TYRA-2 protein 0.001 0.0017 0.0026
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0033 0.0088
Echinococcus multilocularis somatostatin receptor 0.001 0.0017 0.0014
Trypanosoma brucei alpha tubulin, putative 0.0072 0.1546 0.2674
Schistosoma mansoni alpha tubulin 0.0177 0.4135 0.4125
Echinococcus granulosus tubulin alpha chain 0.0177 0.4135 0.4133
Trichomonas vaginalis tubulin gamma chain, putative 0.0127 0.29 0.4389
Echinococcus granulosus G protein coupled receptor 139 0.001 0.0017 0.0014
Schistosoma mansoni hypothetical protein 0.0016 0.0175 0.0158
Echinococcus multilocularis neuropeptide FF receptor 2 0.001 0.0017 0.0014
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.1054 0.1051
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Plasmodium falciparum tubulin beta chain 0.0234 0.5538 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus granulosus tubulin alpha chain 0.0177 0.4135 0.4133
Schistosoma mansoni hypothetical protein 0.0035 0.0632 0.0616
Brugia malayi beta-tubulin, identical 0.0234 0.5538 1
Echinococcus multilocularis g protein coupled receptor 0.001 0.0017 0.0014
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0175 0.0172
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0365 0.2645
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.1054 0.1772
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0.0017 0.0014
Schistosoma mansoni hypothetical protein 0.0041 0.0798 0.0782
Echinococcus multilocularis tubulin alpha chain 0.0177 0.4135 0.4133
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.001 0.0017 0.0026
Echinococcus granulosus neuropeptides capa receptor 0.001 0.0017 0.0014
Schistosoma mansoni thyroid hormone receptor 0.001 0.0033 0.0016
Brugia malayi sulfakinin receptor protein 0.001 0.0017 0.0031
Echinococcus multilocularis insulin receptor 0.0048 0.0972 0.0969
Loa Loa (eye worm) BEN-1 protein 0.0234 0.5538 1
Trypanosoma brucei epsilon tubulin 0.0127 0.29 0.5159
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.1858 0.1844
Brugia malayi nuclear hormone receptor 0.001 0.0033 0.006
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Schistosoma mansoni coup transcription factor 0.001 0.0033 0.0016
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0175 0.0172
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0055 0.1135 1
Brugia malayi hypothetical protein 0.001 0.0017 0.0031
Trypanosoma cruzi tubulin delta chain 0.0055 0.1135 0.1921
Schistosoma mansoni tubulin subunit alpha 0.0177 0.4135 0.4125
Echinococcus granulosus dro:myosuppressin receptor 0.001 0.0017 0.0014
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.1303 0.1288
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.1054 0.0463
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0365 0.2645
Schistosoma mansoni tyrosine kinase 0.008 0.1762 0.1748
Schistosoma mansoni patched 1 0.0043 0.0836 0.0821
Leishmania major beta tubulin 0.0234 0.5538 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0177 0.4135 0.4133
Echinococcus granulosus thyrotropin releasing hormone receptor 0.001 0.0017 0.0014
Trichomonas vaginalis tubulin alpha chain, putative 0.0072 0.1546 0.1509
Plasmodium vivax tubulin alpha chain, putative 0.0177 0.4135 0.7288
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0033 0.006
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Leishmania major beta tubulin 0.0234 0.5538 1
Echinococcus multilocularis muscleblind protein 0.0151 0.3513 0.3511
Schistosoma mansoni tubulin subunit beta 0.0234 0.5538 0.553
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus granulosus peptide allatostatin:somatostatin 0.001 0.0017 0.0014
Brugia malayi tubulin alpha chain - mouse 0.0177 0.4135 0.7467
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.001 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0498 0.0895
Trichomonas vaginalis tubulin gamma chain, putative 0.0127 0.29 0.4389
Echinococcus granulosus Tubulin beta 2C chain 0.0234 0.5538 0.5537
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0033 0.006
Schistosoma mansoni tubulin subunit beta 0.0234 0.5538 0.553
Brugia malayi Tubulin alpha chain 0.0055 0.1135 0.205
Trypanosoma cruzi epsilon tubulin, putative 0.0127 0.29 0.5159
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.1054 0.1038
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0033 0.0031
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0033 0.0031
Giardia lamblia Gamma tubulin 0.0127 0.29 0.4117
Echinococcus granulosus Tubulin beta 2C chain 0.0234 0.5538 0.5537
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0033 0.006
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0033 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0033 0.006
Leishmania major beta tubulin 0.0234 0.5538 1
Schistosoma mansoni hypothetical protein 0.0016 0.0175 0.0158
Brugia malayi Serotonin receptor 0.001 0.0017 0.0031
Echinococcus granulosus epidermal growth factor receptor 0.0151 0.3507 0.3505
Leishmania major beta tubulin 0.0234 0.5538 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.1054 0.1899
Loa Loa (eye worm) tubulin alpha-2 chain 0.0177 0.4135 0.7466
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus multilocularis orexin receptor type 2 0.001 0.0017 0.0014
Loa Loa (eye worm) melatonin receptor type 1A 0.001 0.0017 0.0026
Echinococcus multilocularis tubulin alpha 3 chain 0.0177 0.4135 0.4133
Trichomonas vaginalis tubulin beta chain, putative 0.0177 0.4135 0.7016
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0033 0.006
Brugia malayi Tubulin beta chain 0.0055 0.1135 0.205
Schistosoma mansoni alpha tubulin 0.0177 0.4135 0.4125
Loa Loa (eye worm) hypothetical protein 0.01 0.2241 0.4043
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Loa Loa (eye worm) tubulin alpha 2 0.0122 0.2781 0.5019
Trichomonas vaginalis tubulin beta chain, putative 0.0177 0.4135 0.7016
Brugia malayi Dopamine receptor protein 2 0.001 0.0017 0.0031
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Echinococcus granulosus hypothetical protein 0.001 0.0017 0.0014
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0365 0.0508
Echinococcus granulosus Tubulin alpha 1 chain 0.0177 0.4135 0.4133
Leishmania major beta tubulin 0.0234 0.5538 1
Echinococcus granulosus GPCR family 2 0.0016 0.0175 0.0172
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Entamoeba histolytica tubulin family protein 0.0234 0.5538 1
Trypanosoma brucei beta tubulin 0.0234 0.5538 1
Echinococcus granulosus orexin receptor type 2 0.001 0.0017 0.0014
Trypanosoma brucei beta tubulin 0.0127 0.29 0.5159
Loa Loa (eye worm) tubulin alpha chain 0.0177 0.4135 0.7466
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0033 0.0031
Schistosoma mansoni hypothetical protein 0.0415 1 1
Echinococcus multilocularis allatostatin A receptor 0.001 0.0017 0.0014
Schistosoma mansoni thyroid hormone receptor 0.001 0.0033 0.0016
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.001 0.0017 0.0014
Brugia malayi hypothetical protein 0.001 0.0017 0.0031
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0017 0.0014
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0033 0.0088
Loa Loa (eye worm) hypothetical protein 0.0016 0.0175 0.0311
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus granulosus neuropeptide FF receptor 2 0.001 0.0017 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.1054 0.0463
Echinococcus granulosus tubulin beta 4A class IVa 0.0234 0.5538 0.5537
Plasmodium vivax tubulin epsilon chain, putative 0.0127 0.29 0.49
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0033 0.0055
Echinococcus multilocularis Tubulin beta 2C chain 0.0234 0.5538 0.5537
Echinococcus multilocularis tubulin alpha chain 0.0177 0.4135 0.4133
Brugia malayi MAP kinase sur-1 0.0052 0.1054 0.1903
Brugia malayi neuropeptide F receptor 0.001 0.0017 0.0031
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0033 0.006
Echinococcus granulosus neuropeptide receptor 0.001 0.0017 0.0014
Echinococcus granulosus allatostatin A receptor 0.001 0.0017 0.0014
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.1858 0.3355
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0033 0.006
Echinococcus multilocularis biogenic amine (5HT) receptor 0.001 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0365 0.5
Brugia malayi G protein-coupled receptor 0.001 0.0017 0.0031
Echinococcus multilocularis g protein coupled receptor 0.001 0.0017 0.0014
Echinococcus granulosus tubulin subunit beta 0.0234 0.5538 0.5537
Brugia malayi Cytochrome P450 family protein 0.0012 0.0088 0.0159
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Echinococcus granulosus neuropeptide s receptor 0.001 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Trichomonas vaginalis tubulin epsilon chain, putative 0.0177 0.4135 0.7016
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0017 0.0014
Toxoplasma gondii beta tubulin 0.0234 0.5538 1
Brugia malayi Furin-like cysteine rich region family protein 0.0151 0.3507 0.6333
Brugia malayi Tubulin alpha chain 0.0177 0.4135 0.7467
Brugia malayi Dopamine receptor 0.001 0.0017 0.0031
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0033 0.0031
Echinococcus granulosus tachykinin peptides receptor 99D 0.001 0.0017 0.0014
Echinococcus multilocularis neuropeptide receptor 0.001 0.0017 0.0014
Schistosoma mansoni tubulin subunit delta 0.0055 0.1135 0.112
Plasmodium vivax tubulin beta chain, putative 0.0234 0.5538 1
Echinococcus granulosus tubulin epsilon chain 0.0127 0.29 0.2898
Echinococcus granulosus expressed conserved protein 0.0094 0.2091 0.2089
Brugia malayi Cell division protein ftsZ 0.0055 0.1135 0.205
Trichomonas vaginalis tubulin, putative 0.0072 0.1546 0.1509
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0048 0.0972 0.0969
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0033 0.006
Echinococcus multilocularis serotonin receptor 0.001 0.0017 0.0014
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0836 0.0834
Onchocerca volvulus 0.0072 0.1546 0.8303
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0033 0.006
Echinococcus multilocularis Tubulin alpha 1 chain 0.0177 0.4135 0.4133
Trichomonas vaginalis tubulin alpha chain, putative 0.0127 0.29 0.4389
Echinococcus multilocularis dnaJ subfamily B 0.0415 1 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.1054 0.1332
Trichomonas vaginalis tubulin alpha chain, putative 0.0072 0.1546 0.1509
Echinococcus multilocularis tubulin alpha chain 0.0177 0.4135 0.4133
Schistosoma mansoni hypothetical protein 0.0052 0.1073 0.1058
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.1026 0.1849
Trypanosoma brucei tubulin gamma chain 0.0127 0.29 0.5159
Schistosoma mansoni cpg binding protein 0.0031 0.0539 0.0523
Trichomonas vaginalis tubulin, putative 0.0072 0.1546 0.1509
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.1054 0.1772
Giardia lamblia Beta tubulin 0.0234 0.5538 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0033 0.006
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.001 0.0017 0.0014
Echinococcus multilocularis Tubulin alpha 1 chain 0.0177 0.4135 0.4133
Trichomonas vaginalis tubulin epsilon chain, putative 0.0177 0.4135 0.7016
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Schistosoma mansoni hypothetical protein 0.0172 0.4014 0.4004
Echinococcus multilocularis sex peptide receptor 0.001 0.0017 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0017 0.0014
Giardia lamblia Alpha-tubulin 0.0177 0.4135 0.6872
Echinococcus granulosus beta tubulin 0.0234 0.5538 0.5537
Leishmania major beta tubulin 0.0234 0.5538 1
Echinococcus multilocularis tubulin subunit beta 0.0234 0.5538 0.5537
Trypanosoma cruzi epsilon tubulin, putative 0.0127 0.29 0.5159
Plasmodium falciparum tubulin gamma chain 0.0127 0.29 0.49
Echinococcus multilocularis Tubulin beta 2C chain 0.0234 0.5538 0.5537
Echinococcus granulosus 7TM GPCR rhodopsin 0.001 0.0017 0.0014
Loa Loa (eye worm) tubulin beta-1 chain 0.0234 0.5538 1
Echinococcus granulosus tubulin alpha 1C chain 0.0177 0.4135 0.4133
Leishmania major beta tubulin 0.0234 0.5538 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0033 0.0016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0017 0.0014
Echinococcus granulosus Tubulin beta 2C chain 0.0234 0.5538 0.5537
Brugia malayi tubulin alpha-2 chain 0.0177 0.4135 0.7467
Loa Loa (eye worm) hypothetical protein 0.0043 0.0836 0.1506
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.001 0.0017 0.0014
Echinococcus multilocularis Tubulin beta 2C chain 0.0234 0.5538 0.5537
Loa Loa (eye worm) TK/EGFR protein kinase 0.0151 0.3507 0.6331
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0033 0.0016
Loa Loa (eye worm) hypothetical protein 0.0151 0.3513 0.6342
Echinococcus multilocularis g-protein coupled receptor 0.001 0.0017 0.0014
Echinococcus granulosus alpha tubulin 0.0177 0.4135 0.4133
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0033 0.0055
Brugia malayi hypothetical protein 0.001 0.0017 0.0031
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0033 0.0031
Echinococcus granulosus tubulin alpha 0.0127 0.29 0.2898
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.1054 0.1051
Loa Loa (eye worm) hypothetical protein 0.001 0.0033 0.0055
Trypanosoma brucei zeta tubulin 0.0055 0.1135 0.1921
Plasmodium falciparum alpha tubulin 2 0.0177 0.4135 0.7288
Trypanosoma brucei beta tubulin 0.0234 0.5538 1
Trypanosoma brucei alpha tubulin 0.0177 0.4135 0.7426
Echinococcus granulosus tubulin alpha 3 chain 0.0177 0.4135 0.4133
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.2241 0.3626
Brugia malayi hypothetical protein 0.001 0.0017 0.0031
Brugia malayi Dopamine receptor protein 1 0.001 0.0017 0.0031
Echinococcus granulosus g-protein coupled receptor 0.001 0.0017 0.0014
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.114 0.1499
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0033 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Schistosoma mansoni tyrosine kinase 0.0048 0.0972 0.0956
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.001 0.0017 0.0014
Echinococcus multilocularis peroxisome assembly protein 26 0.0177 0.4135 0.4133
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0033 0.0055
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0836 0.0834
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0175 0.0316
Echinococcus granulosus neuropeptide receptor A26 0.001 0.0017 0.0014
Schistosoma mansoni tyrosine kinase 0.0081 0.1783 0.1769
Giardia lamblia Alpha-tubulin 0.0177 0.4135 0.6872
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.1026 0.1853
Loa Loa (eye worm) hypothetical protein 0.0105 0.237 0.4277
Echinococcus granulosus neuropeptides capa receptor 0.001 0.0017 0.0014
Echinococcus granulosus biogenic amine 5HT receptor 0.001 0.0017 0.0014
Brugia malayi Tubulin beta-1 chain 0.0234 0.5538 1
Echinococcus multilocularis neuropeptide Y receptor 0.001 0.0017 0.0014
Leishmania major beta tubulin 0.0234 0.5538 1
Trichomonas vaginalis tubulin beta chain, putative 0.0177 0.4135 0.7016
Leishmania major zeta tubulin, putative 0.0055 0.1135 0.1921
Giardia lamblia Epsilon tubulin 0.0055 0.1135 0.0181
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0177 0.4135 0.7016
Brugia malayi Tubulin gamma chain 0.0127 0.29 0.5237
Trichomonas vaginalis tubulin beta chain, putative 0.0177 0.4135 0.7016
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.2241 0.4046
Echinococcus granulosus somatostatin receptor 0.001 0.0017 0.0014
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.1054 0.1772
Plasmodium vivax tubulin alpha chain, putative 0.0177 0.4135 0.7288
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0033 0.0031
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.001 0.0017 0.0026
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0033 0.0016
Echinococcus multilocularis 0.0047 0.0934 0.0932
Leishmania major beta tubulin 0.0234 0.5538 1
Trypanosoma brucei tubulin delta chain 0.0055 0.1135 0.1921
Entamoeba histolytica tubulin alpha-1 chain 0.0177 0.4135 0.7288
Brugia malayi Melatonin receptor type 1A 0.001 0.0017 0.0031
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0.0017 0.0014
Loa Loa (eye worm) alpha-tubulin 0.0177 0.4135 0.7466
Loa Loa (eye worm) neuropeptide F receptor 0.001 0.0017 0.0026
Mycobacterium tuberculosis Cell division protein FtsZ 0.0055 0.1135 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0033 0.0031
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0122 0.2781 0.4136
Brugia malayi gonadotropin-releasing hormone receptor 2 0.001 0.0017 0.0031
Brugia malayi G protein-coupled receptor F59B2.13 0.001 0.0017 0.0031
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Trypanosoma brucei alpha tubulin 0.0177 0.4135 0.7426
Echinococcus multilocularis Tubulin beta 2C chain 0.0234 0.5538 0.5537
Onchocerca volvulus 0.001 0.0033 0.0088
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0033 0.0031
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0017 0.0014
Schistosoma mansoni hypothetical protein 0.0172 0.4014 0.4004
Trypanosoma brucei zeta tubulin, putative 0.0055 0.1135 0.1921
Leishmania major beta tubulin 0.0234 0.5538 1
Echinococcus granulosus tubulin subunit TubB 0.0177 0.4135 0.4133
Loa Loa (eye worm) tubulin gamma chain 0.0127 0.29 0.5234
Echinococcus multilocularis fmrfamide receptor 0.001 0.0017 0.0014
Echinococcus granulosus beta tubulin 0.0234 0.5538 0.5537
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus granulosus g protein coupled receptor 0.001 0.0017 0.0014
Trichomonas vaginalis tubulin, putative 0.0055 0.1135 0.0635
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0017 0.0014
Leishmania major beta tubulin 0.0234 0.5538 1
Trypanosoma brucei epsilon tubulin 0.0127 0.29 0.5159
Brugia malayi GnHR receptor homolog 0.001 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0122 0.2781 0.5019
Echinococcus multilocularis neuropeptides capa receptor 0.001 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Brugia malayi neuropeptide F receptor 0.001 0.0017 0.0031
Echinococcus granulosus Tubulin alpha 1 chain 0.0177 0.4135 0.4133
Schistosoma mansoni hypothetical protein 0.0041 0.0798 0.0782
Plasmodium falciparum alpha tubulin 1 0.0177 0.4135 0.7288
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus granulosus tubulin gamma 1 chain 0.0127 0.29 0.2898
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0.0017 0.0014
Schistosoma mansoni tubulin subunit beta 0.0055 0.1135 0.112
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Schistosoma mansoni tubulin subunit beta 0.0234 0.5538 0.553
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.2241 0.2238
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Schistosoma mansoni tubulin subunit beta 0.0234 0.5538 0.553
Echinococcus multilocularis cpg binding protein 0.0031 0.0539 0.0537
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus granulosus tubulin alpha 3 chain 0.0177 0.4135 0.4133
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0017 0.0014
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0175 0.0172
Echinococcus multilocularis epidermal growth factor receptor 0.0081 0.1783 0.1781
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0017 0.0014
Loa Loa (eye worm) TK/INSR protein kinase 0.0048 0.0972 0.175
Brugia malayi RE15519p 0.001 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0035 0.0632 0.1137
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.1054 0.0463
Echinococcus multilocularis tubulin alpha 1C chain 0.0177 0.4135 0.4133
Echinococcus granulosus epidermal growth factor receptor 0.0081 0.1783 0.1781
Loa Loa (eye worm) hypothetical protein 0.0051 0.1026 0.1849
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0081 0.1783 0.1781
Trypanosoma cruzi alpha tubulin, putative 0.0177 0.4135 0.7426
Brugia malayi Tubulin alpha-2 chain 0.0177 0.4135 0.7467
Brugia malayi hypothetical protein 0.001 0.0017 0.0031
Brugia malayi hypothetical protein 0.001 0.0017 0.0031
Toxoplasma gondii beta-1 tubulin, putative 0.0234 0.5538 1
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.1858 0.1856
Brugia malayi hypothetical protein 0.001 0.0017 0.0031
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0055 0.1135 0.1489
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus multilocularis tubulin alpha 1C chain 0.0177 0.4135 0.4133
Echinococcus granulosus insulin receptor 0.0048 0.0972 0.0969
Giardia lamblia Beta tubulin 0.0234 0.5538 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus multilocularis tubulin gamma 1 chain 0.0127 0.29 0.2898
Trypanosoma cruzi tubulin gamma chain 0.0127 0.29 0.5159
Loa Loa (eye worm) hypothetical protein 0.001 0.0033 0.0055
Echinococcus multilocularis tubulin delta chain 0.0055 0.1135 0.1133
Echinococcus multilocularis neuropeptide receptor A26 0.001 0.0017 0.0014
Schistosoma mansoni tyrosine kinase 0.0151 0.3507 0.3496
Echinococcus granulosus cpg binding protein 0.0031 0.0539 0.0537
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0105 0.237 0.3263
Brugia malayi Tachykinin-like peptides receptor 99D 0.001 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Leishmania major beta tubulin 0.0234 0.5538 1
Echinococcus multilocularis GPCR, family 2 0.0016 0.0175 0.0172
Echinococcus granulosus tubulin alpha chain 0.0177 0.4135 0.4133
Schistosoma mansoni hypothetical protein 0.0016 0.0175 0.0158
Brugia malayi AKH receptor 0.001 0.0017 0.0031
Schistosoma mansoni tubulin subunit alpha 0.0177 0.4135 0.4125
Echinococcus granulosus Tubulin beta 2C chain 0.0234 0.5538 0.5537
Schistosoma mansoni tubulin subunit epsilon 0.0127 0.29 0.2888
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0033 0.0016
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.1054 0.1772
Leishmania major beta tubulin 0.0234 0.5538 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0175 0.0311
Brugia malayi hypothetical protein 0.001 0.0017 0.0031
Trypanosoma cruzi zeta tubulin, putative 0.0055 0.1135 0.1921
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Loa Loa (eye worm) hypothetical protein 0.001 0.0033 0.0055
Brugia malayi putative neuropeptide receptor NPR1 0.001 0.0017 0.0031
Treponema pallidum cell division protein FtsZ 0.0055 0.1135 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Echinococcus multilocularis neuropeptides capa receptor 0.001 0.0017 0.0014
Loa Loa (eye worm) follicle stimulating hormone receptor 0.001 0.0017 0.0026
Leishmania major beta tubulin 0.0234 0.5538 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0055 0.1135 0.0635
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.001 0.0017 0.0014
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.2279 0.2265
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.1054 0.1772
Brugia malayi steroid hormone receptor 0.001 0.0033 0.006
Loa Loa (eye worm) hypothetical protein 0.001 0.0033 0.0055
Echinococcus multilocularis beta tubulin 0.0234 0.5538 0.5537
Schistosoma mansoni alpha tubulin 0.0177 0.4135 0.4125
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0033 0.0016
Loa Loa (eye worm) tubulin beta-2A chain 0.0234 0.5538 1
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0127 0.29 0.49
Echinococcus granulosus Tubulin alpha 1 chain 0.0177 0.4135 0.4133
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.1054 0.1051
Trypanosoma brucei epsilon tubulin 0.0127 0.29 0.5159
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.001 0.0017 0.0031
Echinococcus multilocularis protein dispatched 1 0.0049 0.0986 0.0983
Echinococcus granulosus neuropeptide receptor 0.001 0.0017 0.0014
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.001 0.0017 0.0026
Echinococcus granulosus peroxisome assembly protein 26 0.0177 0.4135 0.4133
Echinococcus multilocularis tubulin subunit TubB 0.0177 0.4135 0.4133
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0836 0.1506
Trichomonas vaginalis tubulin beta chain, putative 0.0177 0.4135 0.7016
Brugia malayi CXXC zinc finger family protein 0.0029 0.0498 0.09
Loa Loa (eye worm) BEN-1 protein 0.0234 0.5538 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0033 0.0055
Giardia lamblia Beta tubulin 0.0234 0.5538 1
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.1135 0.0635
Mycobacterium ulcerans cell division protein FtsZ 0.0055 0.1135 1
Onchocerca volvulus 0.0084 0.1858 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0072 0.1546 0.1509
Schistosoma mansoni tubulin subunit beta 0.0234 0.5538 0.553
Loa Loa (eye worm) hypothetical protein 0.0084 0.1858 0.3352
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0175 0.0316
Echinococcus granulosus tubulin alpha chain 0.0177 0.4135 0.4133
Leishmania major beta tubulin 0.0234 0.5538 1
Echinococcus multilocularis tubulin beta 1 chain 0.0234 0.5538 0.5537
Echinococcus granulosus neuropeptide Y receptor 0.001 0.0017 0.0014
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.001 0.0017 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0033 0.0055
Echinococcus granulosus alpha 1A adrenergic receptor 0.001 0.0017 0.0014
Brugia malayi G-protein coupled receptor 0.001 0.0017 0.0031
Schistosoma mansoni hypothetical protein 0.0016 0.0175 0.0158
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Trypanosoma cruzi zeta tubulin, putative 0.0055 0.1135 0.1921
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.001 0.0017 0.0014
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0048 0.0972 0.0969
Trichomonas vaginalis tubulin beta chain, putative 0.0177 0.4135 0.7016
Loa Loa (eye worm) G-protein coupled receptor 0.001 0.0017 0.0026
Echinococcus multilocularis hypothetical protein 0.0177 0.4135 0.4133
Brugia malayi Serotonin receptor 0.001 0.0017 0.0031
Echinococcus multilocularis alpha 1A adrenergic receptor 0.001 0.0017 0.0014
Trypanosoma brucei protein kinase, putative 0.0052 0.1054 0.1772
Schistosoma mansoni tyrosine kinase 0.008 0.1762 0.1748
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Leishmania major gamma-tubulin 0.0127 0.29 0.5159
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0177 0.4135 0.7466
Plasmodium vivax tubulin gamma chain, putative 0.0127 0.29 0.49
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0017 0.0014
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.001 0.0017 0.0014
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.2241 0.2238
Leishmania major beta tubulin 0.0234 0.5538 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0088 0.0154
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.1054 0.1772
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0836 0.0834
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0033 0.0031
Entamoeba histolytica tubulin family protein 0.0234 0.5538 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0234 0.5538 0.5537
Loa Loa (eye worm) hypothetical protein 0.001 0.0033 0.0055
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Trypanosoma brucei alpha tubulin 0.0177 0.4135 0.7426
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0017 0.0014
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.0052 0.1074 0.1935
Brugia malayi hypothetical protein 0.001 0.0017 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0033 0.006
Loa Loa (eye worm) tubulin alpha 2 0.0122 0.2781 0.5019
Loa Loa (eye worm) tubulin beta chain 0.0055 0.1135 0.2046
Echinococcus multilocularis tubulin alpha 3 chain 0.0177 0.4135 0.4133
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0055 0.1135 0.0635
Brugia malayi CHE-14 protein 0.0043 0.0836 0.151
Loa Loa (eye worm) tubulin beta-4 chain 0.0234 0.5538 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0033 0.0031
Schistosoma mansoni tyrosine kinase 0.0081 0.1783 0.1769
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0632 0.1142
Echinococcus multilocularis fmrfamide receptor 0.001 0.0017 0.0014
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.1054 0.1772
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0234 0.5538 0.5537
Loa Loa (eye worm) hypothetical protein 0.001 0.0033 0.0055
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus multilocularis epidermal growth factor receptor 0.0151 0.3507 0.3505
Loa Loa (eye worm) hypothetical protein 0.001 0.0033 0.0055
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.1054 0.1051
Echinococcus multilocularis tachykinin peptides receptor 99D 0.001 0.0017 0.0014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0033 0.0031
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0055 0.1135 0.1489
Echinococcus multilocularis tubulin alpha 0.0127 0.29 0.2898
Echinococcus granulosus g protein coupled receptor 0.001 0.0017 0.0014
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0033 0.006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.1026 0.1853
Brugia malayi follicle stimulating hormone receptor 0.001 0.0017 0.0031
Trypanosoma cruzi beta tubulin, putative 0.0234 0.5538 1
Brugia malayi Cytochrome P450 family protein 0.0012 0.0088 0.0159
Brugia malayi larval opioid receptor 0.001 0.0017 0.0031
Trypanosoma cruzi tubulin delta chain 0.0055 0.1135 0.1921
Echinococcus multilocularis neuropeptide Y receptor 0.001 0.0017 0.0014
Echinococcus granulosus g protein coupled receptor 0.001 0.0017 0.0014
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Echinococcus granulosus sex peptide receptor 0.001 0.0017 0.0014
Brugia malayi alpha-tubulin 0.0177 0.4135 0.7467
Plasmodium vivax delta tubulin, putative 0.0055 0.1135 0.1489
Loa Loa (eye worm) tubulin alpha-3 chain 0.0105 0.237 0.4277
Loa Loa (eye worm) neuropeptide F receptor 0.001 0.0017 0.0026
Schistosoma mansoni tubulin subunit beta 0.0234 0.5538 0.553
Plasmodium falciparum tubulin epsilon chain, putative 0.0127 0.29 0.49
Brugia malayi putative neuropeptide receptor 0.001 0.0017 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0017 0.0014
Echinococcus granulosus serotonin receptor 0.001 0.0017 0.0014
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.001 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0033 0.0055
Schistosoma mansoni nuclear hormone receptor 0.001 0.0033 0.0016
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0033 0.006
Echinococcus multilocularis serotonin receptor 0.001 0.0017 0.0014
Echinococcus granulosus tubulin alpha chain 0.0177 0.4135 0.4133
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.1135 0.0635
Leishmania major delta tubulin, putative 0.0055 0.1135 0.1921
Brugia malayi hypothetical protein 0.001 0.0017 0.0031
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Brugia malayi Protein kinase domain containing protein 0.0048 0.0972 0.1754
Toxoplasma gondii alpha tubulin TUBA1 0.0177 0.4135 0.7288
Toxoplasma gondii alpha-tubulin I, putative 0.0177 0.4135 0.7288
Entamoeba histolytica tubulin gamma chain 0.0127 0.29 0.49
Echinococcus multilocularis expressed conserved protein 0.0094 0.2091 0.2089
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0017 0.0014
Loa Loa (eye worm) tubulin alpha 2 0.005 0.1016 0.183
Schistosoma mansoni tyrosine kinase 0.0048 0.0972 0.0956
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Trichomonas vaginalis tubulin beta chain, putative 0.0234 0.5538 1
Loa Loa (eye worm) G-protein coupled receptor 0.001 0.0017 0.0026
Brugia malayi Serotonin/octopamine receptor family protein 7 0.001 0.0017 0.0031
Echinococcus multilocularis tubulin epsilon chain 0.0127 0.29 0.2898
Echinococcus multilocularis g protein coupled receptor 0.001 0.0017 0.0014
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.1858 0.1856
Brugia malayi ORL1-like opioid receptor 0.001 0.0017 0.0031
Leishmania major alpha tubulin 0.0177 0.4135 0.7426
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.3296 0.3294
Trypanosoma brucei beta tubulin 0.0234 0.5538 1
Loa Loa (eye worm) CYP4Cod1 0.0012 0.0088 0.0154
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0033 0.0031
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0033 0.0088
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.3296 0.3294
Echinococcus multilocularis geminin 0.0172 0.4014 0.4013
Leishmania major epsilon tubulin, putative 0.0127 0.29 0.5159
Schistosoma mansoni tubulin subunit alpha 0.0177 0.4135 0.4125
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus granulosus tubulin alpha 1C chain 0.0177 0.4135 0.4133
Schistosoma mansoni cpg binding protein 0.0031 0.0539 0.0523
Trichomonas vaginalis tubulin, putative 0.0234 0.5538 1
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.1054 0.0463
Trichomonas vaginalis tubulin gamma chain, putative 0.0055 0.1135 0.0635
Plasmodium falciparum tubulin delta chain, putative 0.0055 0.1135 0.1489
Schistosoma mansoni cpg binding protein 0.0029 0.0498 0.0482
Trypanosoma brucei alpha tubulin 0.0177 0.4135 0.7426
Schistosoma mansoni hypothetical protein 0.0041 0.0798 0.0782
Entamoeba histolytica tubulin alpha chain, putative 0.0177 0.4135 0.7288
Schistosoma mansoni tyrosine kinase 0.008 0.1762 0.1748
Trichomonas vaginalis tubulin epsilon chain, putative 0.0234 0.5538 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0234 0.5538 1
Echinococcus multilocularis tubulin alpha chain 0.0177 0.4135 0.4133
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0033 0.006
Echinococcus multilocularis neuropeptide receptor 0.001 0.0017 0.0014
Trypanosoma brucei beta tubulin 0.0234 0.5538 1
Echinococcus granulosus tubulin delta chain 0.0055 0.1135 0.1133
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0017 0.0014
Toxoplasma gondii beta-tubulin, putative 0.0234 0.5538 1
Echinococcus granulosus neuropeptide Y receptor 0.001 0.0017 0.0014
Brugia malayi G-protein coupled receptor 0.001 0.0017 0.0031
Echinococcus granulosus tubulin beta 1 chain 0.0234 0.5538 0.5537
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0033 0.0055
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0033 0.0031
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0033 0.0016
Echinococcus granulosus fmrfamide receptor 0.001 0.0017 0.0014
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.001 0.0017 0.0031
Schistosoma mansoni tubulin subunit alpha 0.0055 0.1135 0.112
Echinococcus multilocularis protein patched 0.0043 0.0836 0.0834
Brugia malayi Tubulin alpha-2 chain 0.0177 0.4135 0.7467
Echinococcus multilocularis G-protein coupled receptor, putative 0.001 0.0017 0.0014
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Trichomonas vaginalis tubulin alpha chain, putative 0.0234 0.5538 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0012 0.0088 0.0154
Loa Loa (eye worm) tubulin alpha chain 0.0177 0.4135 0.7466
Loa Loa (eye worm) tubulin beta chain 0.0234 0.5538 1
Brugia malayi Tubulin beta chain 0.0072 0.1546 0.2791
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0017 0.0014
Echinococcus granulosus FTZ F1 alpha 0.001 0.0033 0.0031
Echinococcus granulosus muscleblind protein 0.0151 0.3513 0.3511
Giardia lamblia Delta tubulin 0.0055 0.1135 0.0181
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.001 0.0017 0.0031
Echinococcus granulosus geminin 0.0172 0.4014 0.4013
Echinococcus multilocularis neuropeptide s receptor 0.001 0.0017 0.0014
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.001 0.0017 0.0014
Loa Loa (eye worm) alpha-tubulin 0.0177 0.4135 0.7466
Loa Loa (eye worm) hypothetical protein 0.0151 0.3513 0.6342
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.001 0.0017 0.0014
Brugia malayi Muscleblind-like protein 0.0151 0.3513 0.6343
Brugia malayi nuclear receptor NHR-88 0.001 0.0033 0.006
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0017 0.0014
Schistosoma mansoni tubulin subunit gamma 0.0127 0.29 0.2888
Echinococcus multilocularis dro:myosuppressin receptor 0.001 0.0017 0.0014
Trichomonas vaginalis tubulin beta chain, putative 0.0072 0.1546 0.1509
Echinococcus multilocularis tubulin alpha chain 0.0177 0.4135 0.4133
Schistosoma mansoni hypothetical protein 0.0041 0.0798 0.0782
Echinococcus granulosus rhodopsin orphan GPCR 0.001 0.0017 0.0014
Echinococcus granulosus tm gpcr rhodopsin 0.001 0.0017 0.0014
Echinococcus multilocularis beta tubulin 0.0234 0.5538 0.5537
Echinococcus multilocularis G protein coupled receptor 139 0.001 0.0017 0.0014
Leishmania major beta tubulin 0.0234 0.5538 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0033 0.0031
Echinococcus granulosus 7tm_1 domain containing protein 0.001 0.0017 0.0014
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0033 0.0016
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Loa Loa (eye worm) beta-tubulin 0.0234 0.5538 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.001 0.0017 0.0026
Trichomonas vaginalis tubulin epsilon chain, putative 0.0234 0.5538 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.001 0.0017 0.0014
Brugia malayi ecdysteroid receptor 0.001 0.0033 0.006
Trichomonas vaginalis tubulin alpha chain, putative 0.0072 0.1546 0.1509
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0033 0.006
Onchocerca volvulus 0.0029 0.0498 0.2614
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0033 0.0055
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0175 0.0172
Leishmania major beta tubulin 0.0234 0.5538 1
Mycobacterium leprae cell division protein FtsZ 0.0055 0.1135 1
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0365 0.0508
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0033 0.0055
Loa Loa (eye worm) hypothetical protein 0.001 0.0017 0.0026
Echinococcus multilocularis muscleblind protein 1 0.0151 0.3513 0.3511

Activities

Activity type Activity value Assay description Source Reference
RBA (binding) = 10 % Relative binding affinity for estrogen receptor of rat uterine cytosol ChEMBL. 15743187
RBA (binding) = 27 % Inhibition of [3H]-E2 binding to human Estrogen receptor-alpha ligand binding domain (LBD) expressed in E. coli lysates ChEMBL. 15743187
RBA (binding) = 35 % Inhibition of [3H]-E2 binding to human Estrogen receptor-beta ligand binding domain (LBD) expressed in E. coli lysates ChEMBL. 15743187

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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