Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0034 | 0.3948 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0034 | 0.3948 | 0.3948 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Onchocerca volvulus | 0.0034 | 0.3948 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase | 0.0034 | 0.3948 | 0.3948 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0034 | 0.3948 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0034 | 0.3948 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0034 | 0.3948 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0034 | 0.3948 | 0.5 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0034 | 0.3948 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0034 | 0.3948 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Trypanosoma cruzi | aldo-keto reductase | 0.0034 | 0.3948 | 0.5 |
Onchocerca volvulus | 0.0034 | 0.3948 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0034 | 0.3948 | 0.3948 |
Giardia lamblia | Aldose reductase | 0.0034 | 0.3948 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Entamoeba histolytica | aldose reductase, putative | 0.0034 | 0.3948 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0034 | 0.3948 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0034 | 0.3948 | 0.3948 |
Onchocerca volvulus | 0.0034 | 0.3948 | 0.5 | |
Echinococcus granulosus | aldo keto reductase | 0.0034 | 0.3948 | 0.3948 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0034 | 0.3948 | 0.3948 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Onchocerca volvulus | 0.0034 | 0.3948 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0034 | 0.3948 | 0.3948 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0034 | 0.3948 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0034 | 0.3948 | 0.3948 |
Echinococcus granulosus | aldo keto reductase | 0.0034 | 0.3948 | 0.3948 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Echinococcus granulosus | hypothetical protein | 0.0034 | 0.3948 | 0.3948 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0034 | 0.3948 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0034 | 0.3948 | 0.3948 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0034 | 0.3948 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Leishmania major | prostaglandin f synthase, putative | 0.0034 | 0.3948 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Onchocerca volvulus | 0.0034 | 0.3948 | 0.5 | |
Giardia lamblia | Aldose reductase | 0.0034 | 0.3948 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0034 | 0.3948 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0034 | 0.3948 | 0.3948 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0034 | 0.3948 | 0.3948 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0034 | 0.3948 | 0.3948 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0034 | 0.3948 | 0.5 |
Trypanosoma brucei | prostaglandin f synthase | 0.0034 | 0.3948 | 0.5 |
Onchocerca volvulus | 0.0034 | 0.3948 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0034 | 0.3948 | 0.3948 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0034 | 0.3948 | 0.3948 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0034 | 0.3948 | 0.3948 |
Echinococcus multilocularis | aldo keto reductase | 0.0034 | 0.3948 | 0.3948 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.