Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.4191 | 0.4191 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0148 | 0.3556 | 0.8485 |
Echinococcus granulosus | geminin | 0.0171 | 0.4191 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.3556 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0148 | 0.3556 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0148 | 0.3556 | 0.8485 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0723 | 0.2032 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.3556 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0148 | 0.3556 | 0.8485 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.4191 | 0.4191 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0148 | 0.3556 | 0.8485 |
Echinococcus granulosus | acetylcholinesterase | 0.0148 | 0.3556 | 0.8485 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0148 | 0.3556 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0025 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0148 | 0.3556 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0025 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0723 | 0.2032 |
Echinococcus multilocularis | geminin | 0.0171 | 0.4191 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0148 | 0.3556 | 1 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0148 | 0.3556 | 0.3556 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0723 | 0.2032 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0723 | 0.2032 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0265 | 0.0746 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0265 | 0.0265 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0265 | 0.0746 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0148 | 0.3556 | 0.8485 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0025 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.