Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.2705 | 0.3094 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.1576 | 0.1576 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.003 | 0.0527 | 0.0527 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.2705 | 0.3094 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.006 | 0.1938 | 0.1938 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.1324 | 0.1514 |
Echinococcus multilocularis | tar DNA binding protein | 0.0076 | 0.2705 | 0.2705 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0527 | 0.0602 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0019 | 0 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0053 | 0.1576 | 0.1576 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0 | 0.5 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1139 | 0.1139 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.1324 | 0.1514 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.1576 | 0.1803 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.006 | 0.1938 | 0.1938 |
Echinococcus granulosus | caspase 2 | 0.0043 | 0.1139 | 0.1139 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.104 | 0.119 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0076 | 0.2705 | 0.2705 |
Echinococcus granulosus | tar DNA binding protein | 0.0076 | 0.2705 | 0.2705 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1938 | 0.1938 |
Onchocerca volvulus | 0.0047 | 0.1324 | 1 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.1576 | 0.1576 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0053 | 0.1576 | 0.1576 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0527 | 0.0527 |
Echinococcus multilocularis | caspase 2 | 0.0043 | 0.1139 | 0.1139 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.003 | 0.0527 | 0.0527 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.006 | 0.1938 | 0.1938 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0043 | 0.1139 | 0.1303 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.2705 | 0.3094 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.1324 | 0.1324 |
Echinococcus granulosus | geminin | 0.0205 | 0.8743 | 0.8743 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0019 | 0 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0041 | 0.104 | 0.104 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0019 | 0 | 0.5 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 1 | 1 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0076 | 0.2705 | 0.2705 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.8743 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.2705 | 0.3094 |
Echinococcus multilocularis | geminin | 0.0205 | 0.8743 | 0.8743 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0043 | 0.1139 | 0.7678 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.8743 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0076 | 0.2705 | 0.2705 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0053 | 0.1576 | 0.1576 |
Loa Loa (eye worm) | TAR-binding protein | 0.0076 | 0.2705 | 0.2705 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0053 | 0.1576 | 0.1576 |
Loa Loa (eye worm) | RNA binding protein | 0.0076 | 0.2705 | 0.2705 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0019 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.104 | 0.104 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.1576 | 0.1803 |
Brugia malayi | Cell death protein 3 precursor | 0.0043 | 0.1139 | 0.1139 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.2705 | 0.3094 |
Brugia malayi | hypothetical protein | 0.003 | 0.0527 | 0.0527 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0053 | 0.1576 | 0.1803 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0076 | 0.2705 | 0.2705 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.