Detailed information for compound 1469399

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 538.638 | Formula: C26H26N4O5S2
  • H donors: 0 H acceptors: 4 LogP: 4.29 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: CN(CCN(C(=O)c1ccc(cc1)S(=O)(=O)N(c1ccccc1)C)c1sc2c(n1)cc1c(c2)OCO1)C
  • InChi: 1S/C26H26N4O5S2/c1-28(2)13-14-30(26-27-21-15-22-23(35-17-34-22)16-24(21)36-26)25(31)18-9-11-20(12-10-18)37(32,33)29(3)19-7-5-4-6-8-19/h4-12,15-16H,13-14,17H2,1-3H3
  • InChiKey: LRIOWIZGCOYAIF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica tubulin alpha chain, putative 0.0098 0.1346 1
Trichomonas vaginalis tubulin beta chain, putative 0.005 0.0627 0.1357
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.135 0.2173
Loa Loa (eye worm) hypothetical protein 0.0099 0.1362 0.3045
Echinococcus multilocularis cpg binding protein 0.003 0.0328 0.0326
Brugia malayi Tubulin beta chain 0.005 0.0627 0.1515
Echinococcus granulosus Tubulin alpha 1 chain 0.0098 0.1346 0.1344
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0184 0.0445
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0184 0.0854
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0038 0.045 0.2949
Echinococcus granulosus alpha tubulin 0.0098 0.1346 0.1344
Leishmania major beta tubulin 0.0089 0.121 0.8934
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0052 0.0024
Giardia lamblia Beta tubulin 0.0089 0.121 0.8897
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0052 0.0024
Echinococcus multilocularis tubulin alpha chain 0.0098 0.1346 0.1344
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0112
Schistosoma mansoni tubulin subunit beta 0.0038 0.045 0.0684
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.034 0.0757
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0038 0.045 0.0922
Entamoeba histolytica hypothetical protein 0.0023 0.0216 0.1108
Trypanosoma brucei alpha tubulin, putative 0.005 0.0627 0.4341
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0076 0.0031
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0017 0.0118 0.0077
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0017 0.0118 0.0336
Entamoeba histolytica tubulin alpha-1 chain 0.0098 0.1346 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0037 0.0036
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0118 0.0105
Onchocerca volvulus 0.0029 0.0303 0.1934
Mycobacterium ulcerans hypothetical protein 0.0047 0.0578 0.0539
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0118 0.0105
Loa Loa (eye worm) hypothetical protein 0.0098 0.135 0.3019
Trypanosoma brucei zeta tubulin, putative 0.0038 0.045 0.2949
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0052 0.0024
Leishmania major epsilon tubulin, putative 0.0089 0.121 0.8934
Leishmania major GTP-binding protein, putative 0.0021 0.0184 0.0854
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0017 0.0118 0.0117
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0017 0.0118 0.0336
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0514 0.047
Giardia lamblia Alpha-tubulin 0.0098 0.1346 1
Echinococcus granulosus tubulin alpha 3 chain 0.0098 0.1346 0.1344
Toxoplasma gondii beta tubulin 0.0089 0.121 0.8934
Leishmania major beta tubulin 0.0089 0.121 0.8934
Brugia malayi nuclear receptor NHR-88 0.0012 0.0052 0.0125
Brugia malayi nuclear hormone receptor 0.0012 0.0052 0.0125
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0578 1
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0017 0.0118 0.0336
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0629 0.9398 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0052 0.0125
Leishmania major beta tubulin 0.0089 0.121 0.8934
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0578 0.0539
Plasmodium falciparum tubulin epsilon chain, putative 0.0089 0.121 0.1217
Trypanosoma brucei beta tubulin 0.0089 0.121 0.8934
Echinococcus granulosus tubulin subunit TubB 0.0098 0.1346 0.1344
Echinococcus multilocularis cation transporting ATPase 13A1 0.0017 0.0118 0.0117
Schistosoma mansoni hypothetical protein 0.0031 0.034 0.0501
Echinococcus multilocularis Tubulin beta 2C chain 0.0089 0.121 0.1209
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0112
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0112
Leishmania major alpha tubulin 0.0098 0.1346 1
Trypanosoma brucei P-type H+-ATPase, putative 0.0017 0.0118 0.0336
Echinococcus granulosus snurportin 1 0.0304 0.4468 0.4467
Loa Loa (eye worm) tubulin gamma chain 0.0089 0.121 0.2706
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0017 0.0118 0.0046
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0578 0.3954
Echinococcus granulosus tubulin alpha 3 chain 0.0098 0.1346 0.1344
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0184 0.0182
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0403 0.0401
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0052 0.0125
Schistosoma mansoni P2X receptor subunit 0.023 0.3345 0.5477
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0076 0.0074
Giardia lamblia Beta tubulin 0.0089 0.121 0.8897
Loa Loa (eye worm) hypothetical protein 0.0017 0.0118 0.0261
Trypanosoma cruzi beta tubulin, putative 0.0089 0.121 0.8934
Trichomonas vaginalis tubulin beta chain, putative 0.0098 0.1346 0.3127
Echinococcus multilocularis hypothetical protein 0.0098 0.1346 0.1344
Trichomonas vaginalis tubulin, putative 0.005 0.0627 0.1357
Plasmodium vivax delta tubulin, putative 0.0038 0.045 0.0402
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0052 0.0125
Echinococcus granulosus tubulin alpha 1C chain 0.0098 0.1346 0.1344
Schistosoma mansoni tubulin subunit beta 0.0089 0.121 0.1942
Schistosoma mansoni atpase class VI type 11c 0.0017 0.0118 0.0134
Leishmania major beta tubulin 0.0089 0.121 0.8934
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0298 0.175
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0076 0.0183
Echinococcus granulosus Tubulin alpha 1 chain 0.0098 0.1346 0.1344
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0017 0.0118 0.0117
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0017 0.0118 0.0117
Loa Loa (eye worm) beta-tubulin 0.0089 0.121 0.2706
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0578 0.0539
Entamoeba histolytica tubulin gamma chain 0.0089 0.121 0.8934
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0627 0.1357
Plasmodium vivax importin-beta 2, putative 0.0028 0.0298 0.0238
Schistosoma mansoni P2X receptor subunit 0.023 0.3345 0.5477
Echinococcus multilocularis cation transporting ATPase 13A3 0.0017 0.0118 0.0117
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0017 0.0118 0.0117
Echinococcus multilocularis Tubulin beta 2C chain 0.0089 0.121 0.1209
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0052 0.0125
Leishmania major alpha tubulin 0.0098 0.1346 1
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0118 0.0105
Echinococcus granulosus beta tubulin 0.0089 0.121 0.1209
Loa Loa (eye worm) hypothetical protein 0.0173 0.2489 0.5569
Leishmania major P-type H -ATPase, putative 0.0017 0.0118 0.0336
Loa Loa (eye worm) hypothetical protein 0.0014 0.0076 0.0165
Trypanosoma brucei alpha tubulin 0.0098 0.1346 1
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0017 0.0118 0.0336
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0052 0.005
Echinococcus granulosus Tubulin beta 2C chain 0.0089 0.121 0.1209
Trichomonas vaginalis tubulin epsilon chain, putative 0.0098 0.1346 0.3127
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0298 0.175
Schistosoma mansoni hypothetical protein 0.0031 0.034 0.0501
Trypanosoma cruzi P-type H+-ATPase, putative 0.0017 0.0118 0.0336
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0017 0.0118 0.0046
Echinococcus multilocularis p2X purinoceptor 4 0.023 0.3345 0.3344
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0052 0.0125
Echinococcus multilocularis tubulin alpha chain 0.0098 0.1346 0.1344
Echinococcus multilocularis tubulin alpha chain 0.0098 0.1346 0.1344
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0052 0.0112
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0514 0.0512
Entamoeba histolytica fatty acid elongase, putative 0.0082 0.1105 0.81
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0052 0.0125
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0403 0.0605
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0578 0.3954
Trichomonas vaginalis tubulin gamma chain, putative 0.0089 0.121 0.2793
Leishmania major zeta tubulin, putative 0.0038 0.045 0.2949
Loa Loa (eye worm) hypothetical protein 0.0067 0.0889 0.1986
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0514 0.1079
Trypanosoma brucei epsilon tubulin 0.0089 0.121 0.8934
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0216 0.0346
Echinococcus multilocularis tubulin alpha 3 chain 0.0098 0.1346 0.1344
Trypanosoma cruzi epsilon tubulin, putative 0.0089 0.121 0.8934
Echinococcus multilocularis tumor protein p63 0.0669 1 1
Trypanosoma cruzi zeta tubulin, putative 0.0038 0.045 0.2949
Entamoeba histolytica fatty acid elongase, putative 0.0082 0.1105 0.81
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0017 0.0118 0.0851
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0889 0.2148
Trypanosoma cruzi zeta tubulin, putative 0.0038 0.045 0.2949
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0076 0.0031
Loa Loa (eye worm) hypothetical protein 0.0017 0.0118 0.0261
Echinococcus granulosus p2X purinoceptor 4 0.023 0.3345 0.3344
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0118 0.0336
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0089 0.121 0.1209
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0017 0.0118 0.0046
Echinococcus multilocularis dnaJ subfamily B 0.041 0.6077 0.6076
Echinococcus granulosus tubulin alpha 1C chain 0.0098 0.1346 0.1344
Echinococcus multilocularis tubulin beta 1 chain 0.0089 0.121 0.1209
Leishmania major beta tubulin 0.0089 0.121 0.8934
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.4468 1
Trichomonas vaginalis tubulin beta chain, putative 0.0098 0.1346 0.3127
Trichomonas vaginalis tubulin epsilon chain, putative 0.0089 0.121 0.2793
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0629 0.9398 1
Brugia malayi alpha-tubulin 0.0098 0.1346 0.3252
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0112
Trypanosoma brucei alpha tubulin 0.0098 0.1346 1
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0118 0.0336
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0052 0.0112
Schistosoma mansoni tubulin subunit beta 0.0089 0.121 0.1942
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0017 0.0118 0.0046
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0184 0.0854
Leishmania major beta tubulin 0.0089 0.121 0.8934
Brugia malayi E1-E2 ATPase family protein 0.0017 0.0118 0.0286
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0052 0.005
Echinococcus granulosus tubulin alpha chain 0.0098 0.1346 0.1344
Loa Loa (eye worm) alpha-tubulin 0.0098 0.1346 0.301
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0578 0.3954
Echinococcus granulosus peroxisome assembly protein 26 0.0098 0.1346 0.1344
Leishmania major alpha tubulin 0.0098 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0247 0.0549
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0118 0.0336
Echinococcus multilocularis tubulin gamma 1 chain 0.0089 0.121 0.1209
Loa Loa (eye worm) hypothetical protein 0.0047 0.0578 0.129
Giardia lamblia Alpha-tubulin 0.0098 0.1346 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0247 0.0184
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0052 0.0024
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0629 0.9398 1
Echinococcus multilocularis Tubulin beta 2C chain 0.0089 0.121 0.1209
Schistosoma mansoni tubulin subunit alpha 0.0038 0.045 0.0684
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0017 0.0118 0.0336
Toxoplasma gondii beta-tubulin, putative 0.0089 0.121 0.8934
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0017 0.0118 0.0286
Trypanosoma cruzi proton motive ATPase 1, putative 0.0017 0.0118 0.0336
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.034 0.0338
Loa Loa (eye worm) alpha-tubulin 0.0098 0.1346 0.301
Schistosoma mansoni copper ABC transporter ATPase 0.0017 0.0118 0.0134
Plasmodium falciparum importin beta, putative 0.0028 0.0298 0.0238
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0216 0.1108
Echinococcus granulosus dnaJ subfamily B 0.041 0.6077 0.6076
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0118 0.0105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0052 0.0112
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0118 0.0117
Loa Loa (eye worm) BEN-1 protein 0.0089 0.121 0.2706
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0578 0.0568
Loa Loa (eye worm) calcium ATPase 0.0017 0.0118 0.0261
Brugia malayi ecdysteroid receptor 0.0012 0.0052 0.0125
Trichomonas vaginalis tubulin alpha chain, putative 0.0089 0.121 0.2793
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0578 0.0539
Echinococcus multilocularis Tubulin alpha 1 chain 0.0098 0.1346 0.1344
Onchocerca volvulus 0.0014 0.0076 0.0183
Leishmania major beta tubulin 0.0089 0.121 0.8934
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0052 0.0024
Loa Loa (eye worm) tubulin alpha chain 0.0098 0.1346 0.301
Giardia lamblia Beta tubulin 0.0089 0.121 0.8897
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0076 0.0183
Echinococcus multilocularis peroxisome assembly protein 26 0.0098 0.1346 0.1344
Toxoplasma gondii alpha tubulin TUBA1 0.0098 0.1346 1
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0017 0.0118 0.0077
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0578 0.1396
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0017 0.0118 0.0046
Brugia malayi Tubulin alpha-2 chain 0.0098 0.1346 0.3252
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0578 0.0539
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0017 0.0118 0.0336
Onchocerca volvulus 0.0098 0.135 1
Toxoplasma gondii P-type ATPase PMA1 0.0017 0.0118 0.0336
Echinococcus multilocularis beta tubulin 0.0089 0.121 0.1209
Trichomonas vaginalis tubulin beta chain, putative 0.0098 0.1346 0.3127
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0052 0.005
Schistosoma mansoni type V p-type atpase isoform 0.0017 0.0118 0.0134
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0052 0.005
Brugia malayi hypothetical protein 0.0025 0.0247 0.0597
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0017 0.0118 0.0336
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0017 0.0118 0.0117
Brugia malayi Latrophilin receptor protein 2 0.0031 0.034 0.0821
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0017 0.0118 0.0077
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0184 0.0182
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0629 0.9398 1
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0017 0.0118 0.0117
Echinococcus granulosus Tubulin alpha 1 chain 0.0098 0.1346 0.1344
Echinococcus multilocularis tubulin subunit beta 0.0089 0.121 0.1209
Echinococcus granulosus cpg binding protein 0.003 0.0328 0.0326
Loa Loa (eye worm) tubulin alpha-2 chain 0.0098 0.1346 0.301
Trypanosoma cruzi alpha tubulin, putative 0.0098 0.1346 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0052 0.005
Loa Loa (eye worm) oxidoreductase 0.0014 0.0076 0.0165
Echinococcus multilocularis GPCR, family 2 0.0031 0.034 0.0338
Trichomonas vaginalis glutaminase, putative 0.0282 0.4138 1
Brugia malayi Tubulin alpha chain 0.0098 0.1346 0.3252
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0398 0.0346
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0052 0.005
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0118 0.0105
Toxoplasma gondii P-type ATPase4, putative 0.0017 0.0118 0.0336
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0247 0.135
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0017 0.0118 0.0105
Brugia malayi hypothetical protein 0.0035 0.0403 0.0974
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0247 0.135
Plasmodium vivax copper-transporting ATPase, putative 0.0017 0.0118 0.0046
Entamoeba histolytica tubulin family protein 0.0089 0.121 0.8934
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0216 0.0346
Brugia malayi Cell division protein ftsZ 0.0038 0.045 0.1088
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0076 0.0183
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0118 0.0336
Plasmodium falciparum alpha tubulin 2 0.0098 0.1346 0.1363
Mycobacterium ulcerans glutaminase 0.0282 0.4138 0.4358
Loa Loa (eye worm) tubulin beta-4 chain 0.0089 0.121 0.2706
Plasmodium vivax tubulin alpha chain, putative 0.0098 0.1346 0.1363
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0514 0.3451
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0184 0.0116
Brugia malayi tubulin alpha chain - mouse 0.0098 0.1346 0.3252
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0118 0.0336
Trichomonas vaginalis tubulin beta chain, putative 0.0098 0.1346 0.3127
Entamoeba histolytica hypothetical protein 0.0035 0.0403 0.2577
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0017 0.0118 0.0046
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0017 0.0118 0.0336
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0398 0.0376
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.046 0.3026
Echinococcus granulosus copper transporting ATPase 1 0.0017 0.0118 0.0117
Echinococcus granulosus tubulin beta 1 chain 0.0089 0.121 0.1209
Trypanosoma brucei alpha tubulin 0.0098 0.1346 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0089 0.121 0.2793
Leishmania major calcium-translocating P-type ATPase 0.0017 0.0118 0.0336
Schistosoma mansoni cpg binding protein 0.003 0.0328 0.0481
Entamoeba histolytica fatty acid elongase, putative 0.0082 0.1105 0.81
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0017 0.0118 0.0117
Leishmania major alpha tubulin 0.0098 0.1346 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0052 0.005
Trypanosoma cruzi tubulin gamma chain 0.0089 0.121 0.8934
Onchocerca volvulus 0.0014 0.0076 0.0183
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.2067 0.4996
Echinococcus multilocularis Tubulin beta 2C chain 0.0089 0.121 0.1209
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0076 0.0031
Echinococcus multilocularis beta tubulin 0.0089 0.121 0.1209
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0038 0.045 0.2949
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0017 0.0118 0.0336
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0052 0.005
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0017 0.0118 0.0336
Echinococcus multilocularis tubulin alpha 1C chain 0.0098 0.1346 0.1344
Echinococcus granulosus cation transporting ATPase 13A1 0.0017 0.0118 0.0117
Echinococcus granulosus importin subunit beta 1 0.0028 0.0298 0.0296
Trichomonas vaginalis tubulin gamma chain, putative 0.0038 0.045 0.0922
Leishmania major delta tubulin, putative 0.0038 0.045 0.2949
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.2067 0.2066
Entamoeba histolytica hypothetical protein 0.0035 0.0403 0.2577
Schistosoma mansoni hypothetical protein 0.0031 0.034 0.0501
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0118 0.0336
Trypanosoma cruzi tubulin delta chain 0.0038 0.045 0.2949
Leishmania major gamma-tubulin 0.0089 0.121 0.8934
Giardia lamblia Epsilon tubulin 0.0038 0.045 0.2704
Entamoeba histolytica hypothetical protein 0.0035 0.0403 0.2577
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0112
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0216 0.0346
Echinococcus granulosus tubulin alpha chain 0.0098 0.1346 0.1344
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0059 0.0763 0.1703
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0052 0.0125
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.005 0.0627 0.1357
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0118 0.0105
Onchocerca volvulus 0.005 0.0627 0.4432
Schistosoma mansoni ATPase 0.0017 0.0118 0.0134
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0369 0.0345
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0118 0.0134
Loa Loa (eye worm) tubulin beta-2A chain 0.0089 0.121 0.2706
Schistosoma mansoni hypothetical protein 0.041 0.6077 1
Loa Loa (eye worm) glutaminase 0.0282 0.4138 0.9262
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0118 0.0105
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0017 0.0118 0.0046
Loa Loa (eye worm) hypothetical protein 0.0035 0.0398 0.0887
Trypanosoma brucei beta tubulin 0.0089 0.121 0.8934
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0052 0.0112
Loa Loa (eye worm) hypothetical protein 0.0017 0.0118 0.0261
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.2006 0.2004
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0247 0.0184
Onchocerca volvulus 0.0014 0.0076 0.0183
Echinococcus granulosus Tubulin beta 2C chain 0.0089 0.121 0.1209
Echinococcus multilocularis snurportin 1 0.0304 0.4468 0.4467
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0052 0.0112
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0184 0.0535
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0052 0.005
Schistosoma mansoni tubulin subunit alpha 0.0098 0.1346 0.2167
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0112
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0118 0.0105
Schistosoma mansoni tubulin subunit alpha 0.0098 0.1346 0.2167
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0052 0.0024
Brugia malayi RNA, U transporter 1 0.0081 0.1092 0.264
Echinococcus multilocularis tubulin alpha 0.0089 0.121 0.1209
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0076 0.0031
Plasmodium falciparum copper-transporting ATPase 0.0017 0.0118 0.0046
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0052 0.0024
Schistosoma mansoni cpg binding protein 0.003 0.0328 0.0481
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0017 0.0118 0.0286
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0629 0.9398 1
Echinococcus multilocularis p2X purinoceptor 4 0.023 0.3345 0.3344
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0298 0.0296
Trichomonas vaginalis tubulin beta chain, putative 0.0098 0.1346 0.3127
Leishmania major proton motive ATPase, putative 0.0017 0.0118 0.0336
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0578 0.0539
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0052 0.0125
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0037 0.0036
Brugia malayi Na,K-ATPase alpha subunit 0.0017 0.0118 0.0286
Trypanosoma brucei epsilon tubulin 0.0089 0.121 0.8934
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0052 0.005
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0017 0.0118 0.0286
Toxoplasma gondii beta-1 tubulin, putative 0.0089 0.121 0.8934
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0627 0.1357
Loa Loa (eye worm) hypothetical protein 0.0028 0.0298 0.0663
Plasmodium falciparum tubulin beta chain 0.0089 0.121 0.1217
Loa Loa (eye worm) tubulin alpha 2 0.0009 0.0002 0.0001
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0118 0.0117
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0052 0.0125
Echinococcus granulosus tubulin beta 4A class IVa 0.0089 0.121 0.1209
Leishmania major P-type H -ATPase, putative 0.0017 0.0118 0.0336
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0017 0.0118 0.0336
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.034 0.0338
Loa Loa (eye worm) hypothetical protein 0.0059 0.0763 0.1703
Echinococcus multilocularis Tubulin beta 2C chain 0.0089 0.121 0.1209
Loa Loa (eye worm) acetyltransferase 0.0145 0.2067 0.4625
Loa Loa (eye worm) hypothetical protein 0.0173 0.2489 0.5569
Leishmania major alpha tubulin 0.0098 0.1346 1
Brugia malayi steroid hormone receptor 0.0012 0.0052 0.0125
Brugia malayi E1-E2 ATPase family protein 0.0017 0.0118 0.0286
Trichomonas vaginalis tubulin epsilon chain, putative 0.0038 0.045 0.0922
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0184 0.0854
Echinococcus multilocularis copper transporting ATPase 1 0.0017 0.0118 0.0117
Loa Loa (eye worm) tubulin alpha 2 0.0059 0.0763 0.1703
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0118 0.0117
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0017 0.0118 0.0077
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0017 0.0118 0.0286
Plasmodium vivax tubulin alpha chain, putative 0.0098 0.1346 0.1363
Loa Loa (eye worm) hypothetical protein 0.0017 0.0118 0.0261
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0017 0.0118 0.0105
Echinococcus granulosus cation transporting ATPase 13A3 0.0017 0.0118 0.0117
Brugia malayi Importin beta-1 subunit 0.0028 0.0298 0.072
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0118 0.0336
Loa Loa (eye worm) glutaminase 2 0.0282 0.4138 0.9262
Trypanosoma cruzi tubulin delta chain 0.0038 0.045 0.2949
Entamoeba histolytica fatty acid elongase, putative 0.0082 0.1105 0.81
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.034 0.0338
Echinococcus granulosus Tubulin beta 2C chain 0.0089 0.121 0.1209
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0052 0.005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0052 0.005
Schistosoma mansoni tubulin subunit beta 0.0089 0.121 0.1942
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0052 0.0024
Schistosoma mansoni tubulin subunit beta 0.0089 0.121 0.1942
Schistosoma mansoni importin beta-1 0.0028 0.0298 0.0431
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0076 0.0063
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0017 0.0118 0.0851
Schistosoma mansoni ATPase 0.0017 0.0118 0.0134
Plasmodium falciparum tubulin gamma chain 0.0089 0.121 0.1217
Plasmodium vivax calcium-transporting ATPase, putative 0.0017 0.0118 0.0046
Plasmodium vivax P-type ATPase4, putative 0.0017 0.0118 0.0046
Loa Loa (eye worm) hypothetical protein 0.0035 0.0398 0.0887
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0578 0.1396
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0369 0.0345
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0076 0.0183
Trichomonas vaginalis tubulin epsilon chain, putative 0.0098 0.1346 0.3127
Loa Loa (eye worm) hypothetical protein 0.0035 0.0398 0.0887
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0076 0.0074
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0792 0.1249
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0017 0.0118 0.0336
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0247 0.135
Schistosoma mansoni ran 0.0021 0.0184 0.0243
Leishmania major alpha tubulin 0.0098 0.1346 1
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0629 0.9398 1
Mycobacterium ulcerans cell division protein FtsZ 0.0038 0.045 0.0402
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0017 0.0118 0.0105
Leishmania major beta tubulin 0.0089 0.121 0.8934
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0017 0.0118 0.0077
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0747 0.5284
Onchocerca volvulus 0.0017 0.0118 0.0513
Trypanosoma brucei zeta tubulin 0.0038 0.045 0.2949
Toxoplasma gondii cation-transporting atpase family protein 0.0017 0.0118 0.0336
Plasmodium vivax tubulin gamma chain, putative 0.0089 0.121 0.1217
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0017 0.0118 0.0046
Echinococcus granulosus cation transporting atpase worm 0.0017 0.0118 0.0117
Brugia malayi hypothetical protein 0.0017 0.0118 0.0286
Schistosoma mansoni alpha tubulin 0.0098 0.1346 0.2167
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0514 0.3451
Echinococcus multilocularis tubulin subunit TubB 0.0098 0.1346 0.1344
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0017 0.0118 0.0134
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0017 0.0118 0.0336
Schistosoma mansoni cation-transporting ATPase 0.0017 0.0118 0.0134
Leishmania major beta tubulin 0.0089 0.121 0.8934
Schistosoma mansoni glutaminase 0.0282 0.4138 0.679
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0052 0.0125
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0247 0.135
Schistosoma mansoni ran 0.0021 0.0184 0.0243
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0017 0.0118 0.0261
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0017 0.0118 0.0046
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0076 0.0031
Leishmania major beta tubulin 0.0089 0.121 0.8934
Onchocerca volvulus 0.0047 0.0578 0.4052
Plasmodium falciparum alpha tubulin 1 0.0098 0.1346 0.1363
Echinococcus multilocularis cation transporting atpase worm 0.0017 0.0118 0.0117
Echinococcus multilocularis tubulin alpha chain 0.0098 0.1346 0.1344
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0118 0.0117
Trypanosoma cruzi cation-transporting ATPase, putative 0.0017 0.0118 0.0336
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.034 0.0821
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0059 0.0763 0.1691
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0017 0.0118 0.0336
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0052 0.0125
Brugia malayi glutaminase DH11.1 0.0282 0.4138 1
Leishmania major hypothetical protein, conserved 0.0025 0.0247 0.135
Entamoeba histolytica Ran family GTPase 0.0021 0.0184 0.0854
Echinococcus multilocularis tubulin epsilon chain 0.0089 0.121 0.1209
Schistosoma mansoni coup transcription factor 0.0012 0.0052 0.0024
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0076 0.0031
Schistosoma mansoni P2X receptor subunit 0.023 0.3345 0.5477
Trichomonas vaginalis tubulin, putative 0.0089 0.121 0.2793
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0247 0.0184
Trypanosoma brucei tubulin delta chain 0.0038 0.045 0.2949
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0076 0.0183
Giardia lamblia Delta tubulin 0.0038 0.045 0.2704
Leishmania major beta tubulin 0.0089 0.121 0.8934
Entamoeba histolytica tubulin family protein 0.0089 0.121 0.8934
Brugia malayi beta-tubulin, identical 0.0089 0.121 0.2925
Plasmodium falciparum tubulin delta chain, putative 0.0038 0.045 0.0402
Echinococcus multilocularis tubulin alpha chain 0.0098 0.1346 0.1344
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0098 0.1346 0.3127
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0118 0.0117
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0578 0.0539
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0052 0.005
Leishmania major copper-transporting ATPase-like protein, putative 0.0017 0.0118 0.0336
Trichomonas vaginalis tubulin, putative 0.005 0.0627 0.1357
Echinococcus granulosus Tubulin beta 2C chain 0.0089 0.121 0.1209
Leishmania major beta tubulin 0.0089 0.121 0.8934
Echinococcus granulosus tubulin alpha chain 0.0098 0.1346 0.1344
Schistosoma mansoni eyes absent homolog 0.0173 0.2489 0.4059
Leishmania major alpha tubulin 0.0098 0.1346 1
Brugia malayi hypothetical protein 0.0173 0.2489 0.6014
Entamoeba histolytica hypothetical protein 0.0035 0.0403 0.2577
Loa Loa (eye worm) hypothetical protein 0.0047 0.0578 0.129
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.045 0.0922
Toxoplasma gondii alpha-tubulin I, putative 0.0098 0.1346 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0578 0.3954
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0052 0.0125
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0076 0.0165
Echinococcus multilocularis Tubulin alpha 1 chain 0.0098 0.1346 0.1344
Leishmania major alpha tubulin 0.0098 0.1346 1
Echinococcus granulosus p2X purinoceptor 4 0.023 0.3345 0.3344
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.046 0.0412
Schistosoma mansoni hypothetical protein 0.0035 0.0403 0.0605
Loa Loa (eye worm) BEN-1 protein 0.0089 0.121 0.2706
Plasmodium vivax tubulin beta chain, putative 0.0089 0.121 0.1217
Schistosoma mansoni tubulin subunit beta 0.0089 0.121 0.1942
Trypanosoma cruzi P-type H+-ATPase, putative 0.0017 0.0118 0.0336
Trypanosoma brucei cation-transporting ATPase, putative 0.0017 0.0118 0.0336
Leishmania major alpha tubulin 0.0098 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.034 0.0757
Schistosoma mansoni alpha tubulin 0.0098 0.1346 0.2167
Trypanosoma brucei epsilon tubulin 0.0089 0.121 0.8934
Echinococcus granulosus GPCR family 2 0.0031 0.034 0.0338
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.1362 0.3291
Leishmania major beta tubulin 0.0089 0.121 0.8934
Brugia malayi Tubulin alpha-2 chain 0.0098 0.1346 0.3252
Echinococcus multilocularis Tubulin alpha 1 chain 0.0098 0.1346 0.1344
Brugia malayi Tubulin beta-1 chain 0.0089 0.121 0.2925
Schistosoma mansoni hypothetical protein 0.0067 0.0889 0.141
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0578 0.3954
Loa Loa (eye worm) hypothetical protein 0.0047 0.0586 0.1307
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.1362 0.3291
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0052 0.005
Trichomonas vaginalis tubulin, putative 0.0038 0.045 0.0922
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0089 0.121 0.8934
Schistosoma mansoni tubulin subunit epsilon 0.0089 0.121 0.1942
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0398 0.0346
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0629 0.9398 1
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0017 0.0118 0.0336
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0052 0.005
Trichomonas vaginalis tubulin beta chain, putative 0.0098 0.1346 0.3127
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0017 0.0118 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.045 0.0922
Schistosoma mansoni phosphoserine phosphatase 0.0017 0.0118 0.0134
Trichomonas vaginalis ran, putative 0.0021 0.0184 0.0267
Treponema pallidum cell division protein FtsZ 0.0038 0.045 1
Leishmania major beta tubulin 0.0089 0.121 0.8934
Echinococcus granulosus tubulin epsilon chain 0.0089 0.121 0.1209
Brugia malayi CXXC zinc finger family protein 0.0029 0.0303 0.0732
Brugia malayi hypothetical protein 0.0016 0.0112 0.0271
Leishmania major alpha tubulin 0.0098 0.1346 1
Loa Loa (eye worm) tubulin beta chain 0.0038 0.045 0.1004
Trypanosoma brucei beta tubulin 0.0089 0.121 0.8934
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0112
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0017 0.0118 0.0261
Loa Loa (eye worm) tubulin alpha 2 0.0059 0.0763 0.1703
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0369 0.0345
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0052 0.005
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0184 0.0854
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0017 0.0118 0.0851
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0017 0.0118 0.0336
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0017 0.0118 0.0134
Loa Loa (eye worm) hypothetical protein 0.0017 0.0118 0.0261
Schistosoma mansoni tubulin subunit alpha 0.0098 0.1346 0.2167
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.034 0.0338
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0017 0.0118 0.0336
Echinococcus granulosus tubulin alpha chain 0.0098 0.1346 0.1344
Leishmania major beta tubulin 0.0089 0.121 0.8934
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0076 0.0031
Trypanosoma brucei beta tubulin 0.0089 0.121 0.8934
Loa Loa (eye worm) tubulin beta chain 0.0089 0.121 0.2706
Echinococcus granulosus phospholipid transporting ATPase VA 0.0017 0.0118 0.0117
Trichomonas vaginalis tubulin epsilon chain, putative 0.0089 0.121 0.2793
Loa Loa (eye worm) E1-E2 ATPase 0.0017 0.0118 0.0261
Leishmania major importin beta-1 subunit, putative 0.0023 0.0216 0.1108
Entamoeba histolytica fatty acid elongase, putative 0.0082 0.1105 0.81
Echinococcus granulosus tubulin delta chain 0.0038 0.045 0.0449
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0303 0.0674
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0398 0.0301
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0118 0.0336
Echinococcus granulosus p2X purinoceptor 4 0.023 0.3345 0.3344
Echinococcus granulosus tubulin alpha 0.0089 0.121 0.1209
Brugia malayi Tubulin alpha chain 0.0038 0.045 0.1088
Echinococcus granulosus tubulin subunit beta 0.0089 0.121 0.1209
Trichomonas vaginalis tubulin alpha chain, putative 0.005 0.0627 0.1357
Loa Loa (eye worm) hypothetical protein 0.0047 0.0578 0.129
Loa Loa (eye worm) tubulin beta-1 chain 0.0089 0.121 0.2706
Echinococcus multilocularis tubulin alpha 3 chain 0.0098 0.1346 0.1344
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0052 0.005
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0076 0.0031
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0047 0.0586 0.1256
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0118 0.0117
Trypanosoma brucei P-type H+-ATPase, putative 0.0017 0.0118 0.0336
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0052 0.0125
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0184 0.0408
Trypanosoma brucei tubulin gamma chain 0.0089 0.121 0.8934
Schistosoma mansoni hypothetical protein 0.0304 0.4468 0.7336
Schistosoma mansoni tubulin subunit delta 0.0038 0.045 0.0684
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0052 0.0125
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0017 0.0118 0.0117
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.2067 0.3361
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.046 0.2784
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0076 0.0031
Mycobacterium leprae cell division protein FtsZ 0.0038 0.045 0.746
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0052 0.0112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0578 0.0568
Trichomonas vaginalis tubulin alpha chain, putative 0.0089 0.121 0.2793
Leishmania major alpha tubulin 0.0098 0.1346 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0403 0.0401
Schistosoma mansoni cpg binding protein 0.0029 0.0303 0.044
Leishmania major beta tubulin 0.0089 0.121 0.8934
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0369 0.0345
Loa Loa (eye worm) hypothetical protein 0.0014 0.0076 0.0165
Brugia malayi Tubulin beta chain 0.0038 0.045 0.1088
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0052 0.005
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0052 0.0112
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0017 0.0118 0.0046
Echinococcus granulosus Tubulin beta 2C chain 0.0089 0.121 0.1209
Echinococcus granulosus beta tubulin 0.0089 0.121 0.1209
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0052 0.0024
Schistosoma mansoni tubulin subunit gamma 0.0089 0.121 0.1942
Echinococcus multilocularis tubulin delta chain 0.0038 0.045 0.0449
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0076 0.0165
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0076 0.0031
Plasmodium vivax cation transporting ATPase, putative 0.0017 0.0118 0.0046
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0578 0.0539
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0052 0.0024
Leishmania major beta tubulin 0.0089 0.121 0.8934
Schistosoma mansoni alpha tubulin 0.0098 0.1346 0.2167
Trypanosoma brucei alpha tubulin 0.0098 0.1346 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0184 0.0116
Echinococcus multilocularis tubulin alpha 1C chain 0.0098 0.1346 0.1344
Trichomonas vaginalis tubulin gamma chain, putative 0.0089 0.121 0.2793
Trypanosoma cruzi copper-transporting ATPase, putative 0.0017 0.0118 0.0336
Trypanosoma cruzi epsilon tubulin, putative 0.0089 0.121 0.8934
Echinococcus multilocularis p2X purinoceptor 4 0.023 0.3345 0.3344
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0017 0.0118 0.0336
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0398 0.0346
Leishmania major alpha tubulin 0.0098 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0112
Echinococcus granulosus tubulin gamma 1 chain 0.0089 0.121 0.1209
Brugia malayi tubulin alpha-2 chain 0.0098 0.1346 0.3252
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0017 0.0118 0.0105
Trichomonas vaginalis cation-transporting ATPase, putative 0.0017 0.0118 0.0105
Brugia malayi Tubulin gamma chain 0.0089 0.121 0.2925
Loa Loa (eye worm) hypothetical protein 0.0035 0.0398 0.0887
Loa Loa (eye worm) hypothetical protein 0.0035 0.0398 0.0887
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0578 1
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0017 0.0118 0.0336
Plasmodium vivax tubulin epsilon chain, putative 0.0089 0.121 0.1217
Leishmania major beta tubulin 0.0089 0.121 0.8934
Trichomonas vaginalis tubulin beta chain, putative 0.0089 0.121 0.2793
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0052 0.0125
Schistosoma mansoni P2X receptor subunit 0.023 0.3345 0.5477
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0052 0.0024
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0118 0.0134
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0052 0.0125
Trypanosoma brucei beta tubulin 0.0089 0.121 0.8934
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.1362 0.3045
Schistosoma mansoni tubulin subunit beta 0.0089 0.121 0.1942
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0629 0.9398 1
Giardia lamblia Gamma tubulin 0.0089 0.121 0.8897
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0298 0.175
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0017 0.0118 0.0336
Mycobacterium tuberculosis Cell division protein FtsZ 0.0038 0.045 0.0432
Loa Loa (eye worm) tubulin alpha chain 0.0098 0.1346 0.301
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0578 0.1396
Loa Loa (eye worm) hypothetical protein 0.0098 0.1346 0.301
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0076 0.0183
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0017 0.0118 0.0336
Onchocerca volvulus 0.0014 0.0076 0.0183
Loa Loa (eye worm) tubulin alpha-3 chain 0.0047 0.0586 0.1307
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0052 0.0024
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0118 0.0336
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0017 0.0118 0.0105
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0578 0.3954
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0076 0.0031
Echinococcus granulosus tubulin alpha chain 0.0098 0.1346 0.1344
Schistosoma mansoni hypothetical protein 0.0031 0.034 0.0501
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0052 0.0112
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0514 0.1079

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.