Detailed information for compound 1470547

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 297.779 | Formula: C18H16ClNO
  • H donors: 2 H acceptors: 1 LogP: 4.86 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(c(c1)CNCc1cccc2c1cccc2)O
  • InChi: 1S/C18H16ClNO/c19-16-8-9-18(21)15(10-16)12-20-11-14-6-3-5-13-4-1-2-7-17(13)14/h1-10,20-21H,11-12H2
  • InChiKey: ZVTPVWVHPXBYDS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis serine:threonine protein kinase 38 0.0151 0.0624 0.0624
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0293 0.1353 0.1645
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0624 0.0107
Brugia malayi Protein kinase domain containing protein 0.0151 0.0624 0.0647
Trypanosoma cruzi acetyl-CoA carboxylase 0.1225 0.6133 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0141
Entamoeba histolytica protein kinase, putative 0.0454 0.2177 1
Echinococcus granulosus nervana 2 0.029 0.1336 0.1336
Brugia malayi Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor, puta 0.0069 0.0203 0.021
Brugia malayi nuclear receptor NHR-88 0.0056 0.0136 0.0141
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0441 0.2113 0.2191
Onchocerca volvulus Bile acid receptor homolog 0.0056 0.0136 0.5
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0056 0.0136 0.0141
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0237 0.0237
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0056 0.0136 0.0141
Leishmania major acetyl-CoA carboxylase, putative 0.1978 1 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0203 0.021
Echinococcus multilocularis Glutaredoxin protein 5 0.029 0.1336 0.1336
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0151 0.0624 0.0647
Trichomonas vaginalis AGC family protein kinase 0.0454 0.2177 1
Brugia malayi nuclear hormone receptor 0.0056 0.0136 0.0141
Echinococcus multilocularis serine threonine protein kinase 0.0151 0.0624 0.0624
Schistosoma mansoni laminin gamma-3 chain 0.005 0.0102 0.0102
Loa Loa (eye worm) abnormal epIthelia family member 0.005 0.0102 0.0106
Wolbachia endosymbiont of Brugia malayi carbamoyl phosphate synthase large subunit 0.017 0.0721 0.1476
Schistosoma mansoni serine/threonine kinase 0.0151 0.0624 0.0624
Entamoeba histolytica protein kinase, putative 0.0441 0.2113 0.9701
Trichomonas vaginalis AGC family protein kinase 0.0454 0.2177 1
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0268 0.1223 0.2905
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0151 0.0624 0.0624
Trypanosoma cruzi Protein kinase B 0.0306 0.1417 0.2048
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0754 0.3714 1
Brugia malayi Protein kinase domain containing protein 0.0151 0.0624 0.0647
Trichomonas vaginalis AGC family protein kinase 0.0164 0.0688 0.0514
Entamoeba histolytica protein kinase, putative 0.0151 0.0624 0.2739
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0268 0.1223 0.2905
Schistosoma mansoni retinoic acid receptor RXR 0.0056 0.0136 0.0136
Schistosoma mansoni thyroid hormone receptor 0.0056 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0141
Trichomonas vaginalis AGC family protein kinase 0.0454 0.2177 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0056 0.0136 0.0141
Echinococcus granulosus dihydrolipoyllysine residue acetyltransferase 0.0069 0.0203 0.0203
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0056 0.0136 0.0136
Schistosoma mansoni thyroid hormone receptor 0.0056 0.0136 0.0136
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0268 0.1223 0.2905
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0624 0.0107
Entamoeba histolytica protein kinase, putative 0.0454 0.2177 1
Giardia lamblia Acetyl-CoA carboxylase/pyruvate carboxylase fusion protein, putative 0.0337 0.1579 1
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0754 0.3714 1
Echinococcus granulosus nervana 2 0.029 0.1336 0.1336
Echinococcus granulosus serine:threonine protein kinase N2 0.0151 0.0624 0.0624
Treponema pallidum pyruvate carboxylase subunit B 0.0069 0.0203 0.5
Echinococcus multilocularis slit 2 protein 0.005 0.0102 0.0102
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0754 0.3714 0.3714
Loa Loa (eye worm) hypothetical protein 0.005 0.0102 0.0106
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0624 0.0624
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0268 0.1223 0.3233
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0754 0.3714 0.3714
Schistosoma mansoni carbamoyl-phosphate synthetase 0.017 0.0721 0.0721
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0151 0.0624 0.0624
Echinococcus granulosus pikachurin 0.005 0.0102 0.0102
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0151 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0069 0.0203 0.021
Echinococcus multilocularis FTZ F1 alpha 0.0056 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0069 0.0203 0.021
Brugia malayi Hr1 repeat family protein 0.0151 0.0624 0.0647
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.0136 0.0136
Echinococcus multilocularis protein kinase c epsilon type 0.0151 0.0624 0.0624
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.029 0.1336 0.1336
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0056 0.0136 0.0136
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.0136 0.0136
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0754 0.3714 0.3584
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1432 0.7194 1
Schistosoma mansoni coup transcription factor 0.0056 0.0136 0.0136
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0056 0.0136 0.0136
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.005 0.0102 0.0106
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0056 0.0136 0.0141
Echinococcus granulosus dihydrolipoyllysine residue succinyltransferase 0.0069 0.0203 0.0203
Schistosoma mansoni serine/threonine-protein kinase 0.0306 0.1417 0.1417
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0151 0.0624 0.0624
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0624 0.0624
Trypanosoma brucei glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative 0.017 0.0721 0.0529
Brugia malayi steroid hormone receptor 0.0056 0.0136 0.0141
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0237 0.0237
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0038 0.0038
Onchocerca volvulus Protein ultraspiracle homolog 0.0056 0.0136 0.5
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0056 0.0136 0.0141
Loa Loa (eye worm) hypothetical protein 0.005 0.0102 0.0106
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0268 0.1223 0.2905
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0754 0.3714 0.3714
Brugia malayi dihydrolipoamide S-acetyltransferase precursor, putative 0.0069 0.0203 0.021
Echinococcus granulosus Biotin lipoyl attachment 0.0069 0.0203 0.0203
Echinococcus granulosus NDR protein kinase 0.0151 0.0624 0.0624
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0056 0.0136 0.0136
Brugia malayi ecdysteroid receptor 0.0056 0.0136 0.0141
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.1978 1 1
Brugia malayi p70 ribosomal S6 kinase beta 0.0441 0.2113 0.2191
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0141
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0268 0.1223 0.1223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0056 0.0136 0.0141
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0293 0.1353 0.1645
Brugia malayi protein kinase C II. 0.0151 0.0624 0.0647
Schistosoma mansoni hypothetical protein 0.0037 0.0038 0.0038
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.1432 0.7194 1
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0754 0.3714 1
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0268 0.1223 0.2905
Leishmania major carbamoyl-phosphate synthase, putative 0.017 0.0721 0.0529
Echinococcus granulosus serine/threonine protein kinase 0.0306 0.1417 0.1417
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0056 0.0136 0.0136
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0268 0.1223 0.1041
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0268 0.1223 0.1041
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0056 0.0136 0.0141
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.1978 1 1
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0151 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0151 0.0624 0.0647
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0056 0.0136 0.0136
Toxoplasma gondii pyruvate carboxylase 0.0754 0.3714 0.3584
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0268 0.1223 0.2905
Plasmodium vivax carbamoyl phosphate synthetase, putative 0.017 0.0721 0.0742
Trypanosoma brucei acetyl-CoA carboxylase 0.1978 1 1
Mycobacterium ulcerans carbamoyl phosphate synthase large subunit 0.017 0.0721 0.1476
Echinococcus multilocularis protein kinase c iota type 0.0151 0.0624 0.0624
Brugia malayi Steroid receptor seven-up type 2 0.0056 0.0136 0.0141
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0056 0.0136 0.0136
Schistosoma mansoni nuclear hormone receptor 0.0056 0.0136 0.0136
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0151 0.0624 0.0647
Schistosoma mansoni steroid hormone receptor ad4bp 0.0056 0.0136 0.0136
Echinococcus granulosus ecdysone induced protein 78C 0.0056 0.0136 0.0136
Echinococcus granulosus FTZ F1 alpha 0.0056 0.0136 0.0136
Echinococcus granulosus Protein kinase C brain isozyme 0.0151 0.0624 0.0624
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0754 0.3714 0.3714
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0754 0.3714 0.5922
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0056 0.0136 0.0136
Schistosoma mansoni serine/threonine-protein kinase 0.0306 0.1417 0.1417
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0056 0.0136 0.0141
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0069 0.0203 0.0203
Schistosoma mansoni aspartate carbamoyltransferase 0.017 0.0721 0.0721
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0056 0.0136 0.0141
Trypanosoma brucei rac serine-threonine kinase, putative 0.0454 0.2177 0.2015
Brugia malayi Carboxyl transferase domain containing protein 0.1909 0.9644 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0056 0.0136 0.0136
Echinococcus granulosus protein kinase C gamma type 0.0151 0.0624 0.0624
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0268 0.1223 0.1223
Schistosoma mansoni dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase 0.0069 0.0203 0.0203
Chlamydia trachomatis biotin carboxylase 0.0684 0.3359 1
Echinococcus multilocularis nervana 2 0.029 0.1336 0.1336
Schistosoma mansoni pyruvate carboxylase 0.0754 0.3714 0.3714
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0056 0.0136 0.0141
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.029 0.1336 0.1336
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0056 0.0136 0.0136
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0038 0.0038
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0337 0.1579 0.7204
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0624 0.0624
Brugia malayi EGF-like domain containing protein 0.005 0.0102 0.0106
Echinococcus multilocularis serine:threonine protein kinase N2 0.0151 0.0624 0.0624
Mycobacterium ulcerans pyruvate carboxylase 0.0754 0.3714 1
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0268 0.1223 0.1041
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0293 0.1353 0.194
Brugia malayi hypothetical protein 0.0037 0.0038 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0624 0.0624
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0268 0.1223 0.2905
Leishmania major carboxylase, putative 0.0754 0.3714 0.3584
Schistosoma mansoni RAR-like nuclear receptor 0.0056 0.0136 0.0136
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0151 0.0624 0.0624
Plasmodium falciparum carbamoyl phosphate synthetase 0.017 0.0721 0.0742
Onchocerca volvulus 0.0056 0.0136 0.5
Entamoeba histolytica protein kinase 2, putative 0.0293 0.1353 0.615
Toxoplasma gondii carbamoylphosphate synthetase 0.017 0.0721 0.0529
Echinococcus granulosus slit 2 protein 0.005 0.0102 0.0102
Echinococcus multilocularis ecdysone induced protein 78C 0.0056 0.0136 0.0136
Loa Loa (eye worm) AGC/NDR protein kinase 0.0151 0.0624 0.0647
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0268 0.1223 0.1041
Trichomonas vaginalis AGC family protein kinase 0.0454 0.2177 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0056 0.0136 0.0136
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0151 0.0624 0.0647
Trichomonas vaginalis AGC family protein kinase 0.0454 0.2177 1
Echinococcus granulosus neurogenic locus notch protein 0.005 0.0102 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0056 0.0136 0.0141
Echinococcus multilocularis pikachurin 0.005 0.0102 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0624 0.0624
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.1978 1 1
Schistosoma mansoni dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase 0.0069 0.0203 0.0203
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0038 0.0038
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.005 0.0102 0.0102
Schistosoma mansoni slit 0.005 0.0102 0.0102
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.1909 0.9644 1
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0268 0.1223 0.172
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0056 0.0136 0.0141
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0754 0.3714 0.3584
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0056 0.0136 0.0136
Trypanosoma cruzi glutamine-dependent carbamoyl-phosphate synthetase, putative 0.017 0.0721 0.0874
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0293 0.1353 0.1353
Echinococcus multilocularis dihydrolipoyllysine residue succinyltransferase 0.0069 0.0203 0.0203
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0268 0.1223 0.172
Echinococcus multilocularis neurogenic locus notch protein 0.005 0.0102 0.0102
Entamoeba histolytica PH domain containing protein kinase, putative 0.0306 0.1417 0.6449
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0056 0.0136 0.0141
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0754 0.3714 1
Brugia malayi Protein kinase domain containing protein 0.0454 0.2177 0.2257
Toxoplasma gondii AGC kinase 0.0441 0.2113 0.195
Echinococcus multilocularis nervana 2 0.029 0.1336 0.1336
Trypanosoma brucei unspecified product 0.0495 0.239 0.2232
Echinococcus granulosus Glutaredoxin protein 5 0.029 0.1336 0.1336
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0268 0.1223 0.2905
Loa Loa (eye worm) hypothetical protein 0.005 0.0102 0.0106
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0056 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0141
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0754 0.3714 1
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0268 0.1223 0.2905
Echinococcus multilocularis serine:threonine protein kinase N2 0.0151 0.0624 0.0624
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0268 0.1223 0.2905
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0268 0.1223 0.2905
Echinococcus granulosus serine threonine protein kinase nrc 0.0293 0.1353 0.1353
Loa Loa (eye worm) AGC/AKT protein kinase 0.0454 0.2177 0.2257
Echinococcus multilocularis dihydrolipoyllysine residue acetyltransferase 0.0069 0.0203 0.0203
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0268 0.1223 0.2905
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0151 0.0624 0.0647
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0141
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0056 0.0136 0.5
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0141
Brugia malayi laminin alpha chain 0.005 0.0102 0.0106
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0056 0.0136 0.0141
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0151 0.0624 0.0624
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0056 0.0136 0.0136
Echinococcus granulosus protein kinase c iota type 0.0151 0.0624 0.0624
Echinococcus multilocularis rac serine:threonine kinase 0.0306 0.1417 0.1417
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0754 0.3714 1
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0268 0.1223 0.172
Echinococcus multilocularis Biotin lipoyl attachment 0.0069 0.0203 0.0203
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0056 0.0136 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0056 0.0136 0.0141
Trichomonas vaginalis AGC family protein kinase 0.0454 0.2177 1
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0754 0.3714 0.5922
Brugia malayi Nuclear hormone receptor-like 1 0.0056 0.0136 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0624 0.0624
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0056 0.0136 0.0136
Trichomonas vaginalis AGC family protein kinase 0.0151 0.0624 0.0107
Brugia malayi photoreceptor-specific nuclear receptor 0.0056 0.0136 0.0141
Schistosoma mansoni acetyl-CoA carboxylase 0.1978 1 1
Loa Loa (eye worm) steroid hormone receptor 0.0056 0.0136 0.0141
Schistosoma mansoni atypical protein kinase C 0.0151 0.0624 0.0624
Brugia malayi laminin-like protein K08C7.3 precursor 0.005 0.0102 0.0106
Entamoeba histolytica PH domain containing protein kinase, putative 0.0306 0.1417 0.6449
Loa Loa (eye worm) AGC/PKN protein kinase 0.0151 0.0624 0.0647
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0056 0.0136 0.0141
Echinococcus granulosus protein kinase c epsilon type 0.0151 0.0624 0.0624
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0268 0.1223 0.1223
Schistosoma mansoni cell polarity protein 0.005 0.0102 0.0102
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0056 0.0136 0.0136
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0293 0.1353 0.1353
Brugia malayi Lipoamide acyltransferase component of branched-chain alpha-keto aciddehydrogenase complex, mitochondrial precursor 0.0069 0.0203 0.021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0056 0.0136 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0056 0.0136 0.0141
Schistosoma mansoni carbamoyl-phosphate synthetase 0.017 0.0721 0.0721
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0754 0.3714 1
Schistosoma mansoni dihydrolipoamide S-acetyltransferase 0.0069 0.0203 0.0203
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0306 0.1417 0.2048
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0056 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0141
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0754 0.3714 0.3584
Trypanosoma cruzi glutamine dependent carbamoyl-phosphate synthase, putative 0.017 0.0721 0.0874
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0056 0.0136 0.0136
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0056 0.0136 0.0141
Trichomonas vaginalis AGC family protein kinase 0.0454 0.2177 1
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.0624 0.0624

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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