Detailed information for compound 1470853

Basic information

Technical information
  • TDR Targets ID: 1470853
  • Name: 1-[2-[[5-[(4-chlorophenoxy)methyl]-4-(furan-2 -ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]ethyl] piperidine
  • MW: 432.967 | Formula: C21H25ClN4O2S
  • H donors: 0 H acceptors: 2 LogP: 3.98 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)OCc1nnc(n1Cc1ccco1)SCCN1CCCCC1
  • InChi: 1S/C21H25ClN4O2S/c22-17-6-8-18(9-7-17)28-16-20-23-24-21(26(20)15-19-5-4-13-27-19)29-14-12-25-10-2-1-3-11-25/h4-9,13H,1-3,10-12,14-16H2
  • InChiKey: OQAWLIMCQATBNU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[2-[[5-[(4-chlorophenoxy)methyl]-4-(2-furylmethyl)-1,2,4-triazol-3-yl]sulfanyl]ethyl]piperidine
  • 1-[2-[[5-[(4-chlorophenoxy)methyl]-4-(2-furylmethyl)-1,2,4-triazol-3-yl]thio]ethyl]piperidine
  • ASN 06534726
  • MLS-0007708.0001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni smad 0.0051 0.0554 0.1009
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0085 0.0074
Leishmania major hypothetical protein, conserved 0.0182 0.2326 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.0028 0.0018
Mycobacterium leprae conserved hypothetical protein 0.0043 0.0452 0.3324
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0028 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0274 0.3572 0.6617
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0452 0.1209
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0742 0.1252
Entamoeba histolytica G protein alpha subunit, putative 0.0012 0.0031 0.0458
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0085 0.0238
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0043 0.0452 0.1036
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0012 0.003 0.0034
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0452 0.1209
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0031 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus granulosus tar DNA binding protein 0.0274 0.3572 0.6099
Echinococcus multilocularis Glutaredoxin protein 5 0.002 0.0132 0.0207
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0028 0.003
Loa Loa (eye worm) inositol-1 0.0045 0.0467 0.0457
Echinococcus granulosus receptor type guanylyl cyclase 0.0034 0.032 0.053
Onchocerca volvulus 0.0034 0.032 0.0788
Plasmodium falciparum ataxin-2 like protein, putative 0.0182 0.2326 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0012 0.003 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0699 0.1871
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0028 0.003
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0452 0.1209
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.2641 0.2633
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0549 0.0922
Echinococcus granulosus metabotropic glutamate receptor 5 0.0442 0.5851 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Brugia malayi MH1 domain containing protein 0.0028 0.0245 0.0235
Loa Loa (eye worm) hypothetical protein 0.0043 0.0452 0.0441
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0012 0.003 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Plasmodium vivax ataxin-2 like protein, putative 0.0182 0.2326 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0085 0.0127
Trypanosoma brucei rac serine-threonine kinase, putative 0.0033 0.0306 0.1203
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0012 0.003 0.0034
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0012 0.003 0.0081
Brugia malayi hypothetical protein 0.0034 0.032 0.031
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0028 0.0018
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trypanosoma cruzi extracellular receptor, putative 0.0034 0.032 0.1263
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0021 0.0142 0.0488
Schistosoma mansoni Smad4 0.0023 0.0172 0.0299
Onchocerca volvulus 0.0036 0.0351 0.0871
Schistosoma mansoni hypothetical protein 0.0065 0.0742 0.1358
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0012 0.0031 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0033 0.0306 0.082
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Onchocerca volvulus Poor gastrulation protein homolog 0.0058 0.0652 0.1683
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0028 0.0018
Loa Loa (eye worm) hypothetical protein 0.0058 0.0652 0.0642
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0028 0.003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.0023 0.0172 0.0161
Brugia malayi hypothetical protein 0.0012 0.003 0.002
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0351 0.0583
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0085 0.0127
Echinococcus granulosus expressed protein 0.0012 0.0031 0.0036
Echinococcus granulosus glutamate receptor 2 0.0034 0.032 0.053
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0028 0.0018
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0169 0.3476
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Echinococcus multilocularis Smad4 0.0051 0.0554 0.093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0012 0.003 0.0036
Echinococcus granulosus mitogen activated protein kinase 0.0062 0.0699 0.1179
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0351 0.0583
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi Pre-SET motif family protein 0.0036 0.0351 0.0341
Brugia malayi N-terminal motif family protein 0.0203 0.261 0.2602
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Onchocerca volvulus 0.0012 0.003 0.0005
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0062 0.0699 0.2913
Toxoplasma gondii LsmAD domain-containing protein 0.0182 0.2326 1
Mycobacterium tuberculosis Conserved protein 0.0043 0.0452 0.1036
Entamoeba histolytica hypothetical protein 0.0012 0.003 0.0429
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Trichomonas vaginalis AGC family protein kinase 0.0013 0.0037 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0351 0.0632
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Loa Loa (eye worm) nuclear factor I 0.0028 0.0245 0.0235
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0012 0.003 0.002
Brugia malayi beta-lactamase family protein 0.0043 0.0452 0.0441
Brugia malayi nuclear hormone receptor 0.0012 0.0028 0.0018
Schistosoma mansoni smad1 5 8 and 0.0051 0.0554 0.1009
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Onchocerca volvulus 0.0043 0.0452 0.1142
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0021 0.0142 0.0488
Echinococcus granulosus Smad4 0.0051 0.0554 0.093
Loa Loa (eye worm) hypothetical protein 0.0034 0.032 0.031
Loa Loa (eye worm) hypothetical protein 0.0034 0.032 0.031
Brugia malayi beta-lactamase 0.0043 0.0452 0.0441
Loa Loa (eye worm) hypothetical protein 0.0012 0.0028 0.0018
Echinococcus multilocularis nervana 2 0.002 0.0132 0.0207
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0351 0.0632
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0028 0.003
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0278 0.3624 1
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0031 0.0084
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.3266 0.3259
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0012 0.003 0.0034
Schistosoma mansoni serine/threonine-protein kinase 0.0023 0.0169 0.0295
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0028 0.0033
Toxoplasma gondii AGC kinase 0.0031 0.0279 0.1086
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Entamoeba histolytica protein kinase, putative 0.0033 0.0306 0.6482
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0028 0.0018
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0742 0.0732
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0058 0.0652 0.0642
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.029 0.3788 0.7017
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0012 0.003 0.0034
Echinococcus multilocularis tyrosine kinase 0.0034 0.032 0.053
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0034 0.032 0.053
Echinococcus multilocularis geminin 0.0205 0.2633 0.4491
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0012 0.003 0.0036
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0092 0.111 0.11
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0742 0.0732
Brugia malayi isocitrate dehydrogenase 0.0016 0.0085 0.0074
Schistosoma mansoni hypothetical protein 0.0205 0.2633 0.4873
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.004 0.0403 0.0901
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0034 0.032 0.053
Plasmodium vivax SET domain protein, putative 0.0036 0.0351 0.1397
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0028 0.0018
Echinococcus granulosus beta LACTamase domain containing family member 0.0043 0.0452 0.0755
Toxoplasma gondii hypothetical protein 0.0027 0.0223 0.0842
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni smad1 5 8 and 0.0051 0.0554 0.1009
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Loa Loa (eye worm) glutamate receptor 0.0359 0.4727 0.4721
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.002 0.0132 0.0207
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.091 1
Brugia malayi MH2 domain containing protein 0.0023 0.0172 0.0161
Echinococcus multilocularis mothers against decapentaplegic 5 0.0051 0.0554 0.093
Echinococcus granulosus smad 0.0051 0.0554 0.093
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0031 0.0021
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0028 0.003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis mothers against decapentaplegic 2 0.0023 0.0172 0.0276
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0012 0.003 0.002
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.032 0.053
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0085 0.0127
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0012 0.003 0.0036
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0028 0.003
Brugia malayi Smad1 0.0051 0.0554 0.0544
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0742 0.1252
Echinococcus granulosus mothers against decapentaplegic 2 0.0023 0.0172 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0028 0.0018
Brugia malayi nuclear receptor NHR-88 0.0012 0.0028 0.0018
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0012 0.0031 0.0039
Trypanosoma brucei PAB1-binding protein , putative 0.0182 0.2326 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni smad 0.0023 0.0172 0.0299
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0012 0.003 0.002
Echinococcus multilocularis rac serine:threonine kinase 0.0023 0.0169 0.0272
Loa Loa (eye worm) MH1 domain-containing protein 0.0051 0.0554 0.0544
Loa Loa (eye worm) beta-lactamase 0.0043 0.0452 0.0441
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0043 0.0452 0.1036
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0028 0.0033
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0012 0.003 0.0036
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.004 0.0403 0.2624
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0012 0.0031 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0452 0.1836
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni tar DNA-binding protein 0.0274 0.3572 0.6617
Loa Loa (eye worm) hypothetical protein 0.0034 0.032 0.031
Echinococcus multilocularis smad 0.0051 0.0554 0.093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0699 0.1279
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.091 1
Echinococcus multilocularis mothers against decapentaplegic 6 0.0023 0.0172 0.0276
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0012 0.003 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0028 0.0018
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0012 0.003 0.002
Schistosoma mansoni tyrosine kinase 0.0034 0.032 0.0575
Leishmania major extracellular receptor, putative 0.0034 0.032 0.1263
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi p70 ribosomal S6 kinase beta 0.0031 0.0279 0.0269
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0274 0.3572 0.3565
Echinococcus granulosus nervana 2 0.002 0.0132 0.0207
Trypanosoma brucei protein kinase, putative 0.0062 0.0699 0.2913
Schistosoma mansoni coup transcription factor 0.0012 0.0028 0.0033
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0062 0.0699 0.2913
Echinococcus multilocularis tar DNA binding protein 0.0274 0.3572 0.6099
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0699 0.2913
Brugia malayi TAR-binding protein 0.0274 0.3572 0.3565
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0351 0.0583
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0742 0.1252
Entamoeba histolytica protein kinase 2, putative 0.0021 0.0142 0.2887
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.091 1
Echinococcus granulosus Glutaredoxin protein 5 0.002 0.0132 0.0207
Schistosoma mansoni tyrosine kinase 0.0034 0.032 0.0575
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0012 0.003 0.0036
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0045 0.0467 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Loa Loa (eye worm) glutamate receptor 0.0141 0.1776 0.1768
Brugia malayi MAP kinase sur-1 0.0062 0.0699 0.0689
Trichomonas vaginalis penicillin-binding protein, putative 0.0043 0.0452 0.1209
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0549 0.0922
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0045 0.0467 0.1902
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0012 0.003 0.002
Schistosoma mansoni serine/threonine-protein kinase 0.0023 0.0169 0.0295
Echinococcus multilocularis ubiquitin specific protease 41 0.0012 0.003 0.0034
Onchocerca volvulus 0.0043 0.0452 0.1142
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi G-protein alpha subunit 0.0012 0.0031 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.0028 0.0018
Loa Loa (eye worm) hypothetical protein 0.0148 0.1866 0.1857
Trichomonas vaginalis AGC family protein kinase 0.0033 0.0306 0.082
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0012 0.003 0.0036
Echinococcus multilocularis receptor type guanylyl cyclase 0.0034 0.032 0.053
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0012 0.0031 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0011 0.0028
Loa Loa (eye worm) hypothetical protein 0.0012 0.0028 0.0018
Brugia malayi MH1 domain containing protein 0.0028 0.0245 0.0235
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0467 0.1902
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0012 0.003 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi beta-lactamase family protein 0.0043 0.0452 0.0441
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Schistosoma mansoni protein kinase 0.0034 0.032 0.0575
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0028 0.0018
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0012 0.0031 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus granulosus GPCR family 3 C terminal 0.0058 0.0652 0.1099
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0028 0.0018
Schistosoma mansoni calpain-7 (C02 family) 0.0012 0.003 0.0036
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0012 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0043 0.0452 0.0441
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.029 0.3788 0.3781
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.032 0.053
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0028 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.029 0.3788 0.7017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0028 0.003
Echinococcus multilocularis GPCR, family 2 0.0065 0.0742 0.1252
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0012 0.003 0.0034
Echinococcus multilocularis GPCR, family 3, C terminal 0.0058 0.0652 0.1099
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0028 0.0018
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0021 0.0142 0.0225
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0031 0.0084
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Plasmodium falciparum ataxin-2 like protein, putative 0.0182 0.2326 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0012 0.003 0.0034
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.029 0.3788 0.6468
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0028 0.003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Echinococcus granulosus inositol monophosphatase 1 0.0045 0.0467 0.0781
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0012 0.003 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0021
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0028 0.003
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0549 0.1312
Onchocerca volvulus 0.0034 0.032 0.0788
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0012 0.003 0.0036
Onchocerca volvulus 0.0043 0.0452 0.1142
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0028 0.003
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0012 0.0031 0.0084
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0012 0.0031 0.0036
Trypanosoma cruzi PAB1-binding protein , putative 0.0182 0.2326 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0085 0.0127
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0012 0.003 0.0036
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.002 0.0132 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Echinococcus multilocularis inositol monophosphatase 1 0.0045 0.0467 0.0781
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0028 0.0018
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0085 0.0238
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.032 0.053
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trypanosoma cruzi PAB1-binding protein , putative 0.0182 0.2326 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0325 0.4269 0.4263
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis glutamate receptor 2 0.0034 0.032 0.053
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0028 0.0033
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0012 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.0442 0.5851 0.5846
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0031 0.0039
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0031 0.0021
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0028 0.0033
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0028 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0028 0.0018
Loa Loa (eye worm) RNA binding protein 0.0274 0.3572 0.3565
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0012 0.003 0.002
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0012 0.003 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus granulosus glutamate receptor 2 0.0034 0.032 0.053
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0203 0.261 0.6962
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0031 0.0084
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0028 0.003
Loa Loa (eye worm) G protein alpha subunit 3 0.0012 0.0031 0.0021
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0012 0.003 0.0034
Brugia malayi MH2 domain containing protein 0.0051 0.0554 0.0544
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0012 0.003 0.0034
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0012 0.003 0.0429
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.032 0.053
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0467 0.1902
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0012 0.0031 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0012 0.0031 0.0036
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0467 0.1902
Schistosoma mansoni Smad4 0.0051 0.0554 0.1009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Brugia malayi hypothetical protein 0.0012 0.0031 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Echinococcus granulosus ubiquitin specific peptidase c family 0.0012 0.003 0.0034
Echinococcus granulosus GPCR family 2 0.0065 0.0742 0.1252
Echinococcus granulosus serine threonine protein kinase nrc 0.0021 0.0142 0.0225
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis glutamate receptor 2 0.0034 0.032 0.053
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0012 0.003 0.0036
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0012 0.0031 0.0021
Schistosoma mansoni smad1 5 8 and 0.0051 0.0554 0.1009
Brugia malayi Guanylyl cyclase protein 23 0.0034 0.032 0.031
Echinococcus granulosus geminin 0.0205 0.2633 0.4491
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0031 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0274 0.3572 0.6617
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0012 0.003 0.0036
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0085 0.0127
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.0028 0.0245 0.0235
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0012 0.0031 0.0036
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.091 0.1539
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0028 0.0018
Loa Loa (eye worm) hypothetical protein 0.0034 0.032 0.031
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0012 0.003 0.0429
Loa Loa (eye worm) MH2 domain-containing protein 0.0023 0.0172 0.0161
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0351 0.0632
Trichomonas vaginalis ubiquitin specific protease, putative 0.0012 0.003 0.0081
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0085 0.0238
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0012 0.003 0.0429
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0012 0.0031 0.0021
Echinococcus multilocularis nmda type glutamate receptor 0.0034 0.032 0.053
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0034 0.032 0.0788
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0549 0.1312
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0012 0.0031 0.0039
Echinococcus granulosus metabotropic glutamate receptor 2 0.0301 0.3937 0.6724
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.029 0.3788 0.6468
Mycobacterium tuberculosis Probable hydrolase 0.0043 0.0452 0.1036
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0085 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0028 0.0018
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0012 0.003 0.0036
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0028 0.0018
Schistosoma mansoni GTP-binding protein alpha subunit 0.0012 0.0031 0.0039
Schistosoma mansoni GTP-binding protein alpha subunit 0.0012 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0065 0.0742 0.0732
Loa Loa (eye worm) hypothetical protein 0.0034 0.032 0.031
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0012 0.003 0.0034
Brugia malayi MH2 domain containing protein 0.0051 0.0554 0.0544
Schistosoma mansoni hypothetical protein 0.014 0.1762 0.3253
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.2641 0.2633
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0012 0.0031 0.0036
Brugia malayi Inositol-1 0.0045 0.0467 0.0457
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.029 0.3788 0.6468
Entamoeba histolytica protein kinase, putative 0.0031 0.0279 0.5892
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0012 0.0031 0.0036
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0085 0.0238
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0021 0.0142 0.0488
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.091 0.383
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0012 0.0031 0.0021
Loa Loa (eye worm) hypothetical protein 0.014 0.1762 0.1753
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0012 0.0031 0.0021
Echinococcus granulosus atrial natriuretic peptide receptor 0.0034 0.032 0.053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0028 0.0018
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0012 0.003 0.0036
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0043 0.0452 0.0441
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Brugia malayi ecdysteroid receptor 0.0012 0.0028 0.0018
Schistosoma mansoni metabotropic glutamate receptor 0.0175 0.2234 0.413
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0012 0.0031 0.0021
Loa Loa (eye worm) hypothetical protein 0.0043 0.0452 0.0441
Loa Loa (eye worm) MH2 domain-containing protein 0.0051 0.0554 0.0544
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis mitogen activated protein kinase 3 0.0062 0.0699 0.1179
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Echinococcus granulosus mothers against decapentaplegic 6 0.0023 0.0172 0.0276
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0012 0.003 0.0034
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0351 0.1397
Trichomonas vaginalis inositol monophosphatase, putative 0.0045 0.0467 0.1249
Brugia malayi Pre-SET motif family protein 0.0251 0.3266 0.3259
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0223 0.0842
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0085 0.0238
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0085 0.0238
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0012 0.003 0.0034
Brugia malayi RNA recognition motif domain containing protein 0.0274 0.3572 0.3565
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0699 0.1871
Giardia lamblia Kinase, AGC PKA 0.0021 0.0142 0.1676
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.0028 0.0018
Loa Loa (eye worm) MH2 domain-containing protein 0.0749 1 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0028 0.003
Loa Loa (eye worm) hypothetical protein 0.0043 0.0452 0.0441
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.091 0.5
Echinococcus multilocularis expressed protein 0.0012 0.003 0.0034
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0012 0.003 0.0034
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0085 0.0127
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0012 0.0031 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0028 0.0018
Trichomonas vaginalis ubiquitin specific protease, putative 0.0012 0.003 0.0081
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0012 0.003 0.002
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Schistosoma mansoni peptidase 0.0013 0.0041 0.0056
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.029 0.3788 0.3781
Schistosoma mansoni hypothetical protein 0.0082 0.0968 0.1778
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0085 0.0238
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Brugia malayi hypothetical protein 0.0148 0.1866 0.1857
Loa Loa (eye worm) hypothetical protein 0.0205 0.2641 0.2633
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Loa Loa (eye worm) hypothetical protein 0.0036 0.0351 0.0341
Schistosoma mansoni hypothetical protein 0.0012 0.003 0.0036
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0012 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0021
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0012 0.003 0.0034
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0223 0.0842
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0028 0.0033
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0031 0.0084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0085 0.0138
Brugia malayi ubiquitin specific protease 14 0.0012 0.003 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0028 0.0033
Onchocerca volvulus 0.0012 0.0031 0.0009
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.1762 0.1753
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0028 0.0033
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0031 0.0279 0.0269
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0062 0.0699 0.2913
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Onchocerca volvulus 0.0286 0.3736 1
Brugia malayi steroid hormone receptor 0.0012 0.0028 0.0018
Mycobacterium tuberculosis Conserved protein 0.0043 0.0452 0.1036
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0011 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0028 0.0018
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0301 0.3937 0.6724
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0085 0.0238
Onchocerca volvulus Huntingtin homolog 0.0148 0.1866 0.4957
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0028 0.0033
Trichomonas vaginalis AGC family protein kinase 0.0011 0.0011 0.0028
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0028 0.0033
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0033 0.0306 0.082
Schistosoma mansoni glutamate receptor NMDA 0.0034 0.032 0.0575
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0043 0.0452 0.1036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0028 0.003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0452 0.0819
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Echinococcus granulosus mitogen activated protein kinase 3 0.0062 0.0699 0.1179
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi Receptor family ligand binding region containing protein 0.0034 0.032 0.031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0028 0.0033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.091 0.383
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0012 0.003 0.0034
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0699 0.1871
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Schistosoma mansoni hypothetical protein 0.0065 0.0742 0.1358
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0043 0.0452 0.0441
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0043 0.0452 0.0819
Brugia malayi hypothetical protein 0.0182 0.2326 0.2318
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0045 0.0467 0.0332
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0062 0.0699 0.0689
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0033 0.0306 0.082
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0082 0.0968 0.1639
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0028 0.0018
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.029 0.3788 0.6468
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis esterase, putative 0.0043 0.0452 0.1209
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Leishmania major hypothetical protein, conserved 0.0043 0.0452 0.1836
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0408 0.5393 1
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0092 0.111 0.11
Loa Loa (eye worm) hypothetical protein 0.0182 0.2326 0.2318
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0028 0.003
Echinococcus granulosus TGF beta signal transducer SmadC 0.0051 0.0554 0.093
Trichomonas vaginalis set domain proteins, putative 0.0286 0.3736 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0028 0.0018
Loa Loa (eye worm) hypothetical protein 0.0092 0.111 0.11
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0051 0.0554 0.093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Schistosoma mansoni metabotropic glutamate receptor 0.0301 0.3937 0.7295
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0012 0.003 0.002
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0051 0.0554 0.1009
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0742 0.0732
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0012 0.0031 0.0084
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0028 0.003
Schistosoma mansoni calpain-7 (C02 family) 0.0012 0.003 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0062 0.0699 0.2913
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0012 0.0031 0.0084
Brugia malayi Probable ClpP-like protease 0.0077 0.091 0.09
Brugia malayi metabotropic glutamate receptor type 2 0.0175 0.2234 0.2225
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0034 0.032 0.053
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.091 0.383
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.0043 0.0452 0.0441
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0012 0.0031 0.0039
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0012 0.003 0.0034
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.091 0.383
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0012 0.003 0.0034
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0467 0.1249
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0442 0.5851 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0045 0.0467 0.1249
Loa Loa (eye worm) MH1 domain-containing protein 0.0023 0.0172 0.0161
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0012 0.003 0.0034
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Schistosoma mansoni inositol monophosphatase 0.0045 0.0467 0.0848
Entamoeba histolytica protein kinase, putative 0.0033 0.0306 0.6482
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0012 0.003 0.0036
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0012 0.0031 0.0021
Giardia lamblia Kinase, CMGC MAPK 0.0062 0.0699 1
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0045 0.0467 0.1902
Schistosoma mansoni tar DNA-binding protein 0.0274 0.3572 0.6617
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Echinococcus granulosus tyrosine kinase 0.0034 0.032 0.053
Mycobacterium tuberculosis Probable esterase LipL 0.0043 0.0452 0.1036
Schistosoma mansoni inositol monophosphatase 0.0045 0.0467 0.0848
Loa Loa (eye worm) RGC/RGC protein kinase 0.0034 0.032 0.031
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0012 0.003 0.002
Brugia malayi RNA binding protein 0.0274 0.3572 0.3565
Echinococcus multilocularis expressed protein 0.0012 0.0031 0.0036
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0028 0.003
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0058 0.0652 0.1683
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0012 0.003 0.0036
Brugia malayi hypothetical protein 0.0117 0.1453 0.1444
Onchocerca volvulus 0.0012 0.003 0.0005
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0062 0.0699 0.2913
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0012 0.003 0.0034
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0333 0.0552
Echinococcus multilocularis nervana 2 0.002 0.0132 0.0207
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0012 0.003 0.0034
Schistosoma mansoni hypothetical protein 0.0065 0.0742 0.1358
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.0699 0.1871
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0012 0.0031 0.0036
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0012 0.003 0.0036
Loa Loa (eye worm) TAR-binding protein 0.0274 0.3572 0.3565
Loa Loa (eye worm) AGC/AKT protein kinase 0.0033 0.0306 0.0296
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0012 0.003 0.0034
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0062 0.0699 0.2913
Mycobacterium tuberculosis Probable lipase LipE 0.0043 0.0452 0.1036
Loa Loa (eye worm) transcription factor SMAD2 0.0749 1 1
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0023 0.0169 0.0606
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0012 0.003 0.0036
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0034 0.032 0.053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0028 0.0018
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Schistosoma mansoni Smad4 0.0023 0.0172 0.0299
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0012 0.0031 0.0084
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0034 0.032 0.053
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Mycobacterium tuberculosis Conserved protein 0.0043 0.0452 0.1036
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0023 0.0172 0.0387
Trichomonas vaginalis AGC family protein kinase 0.0033 0.0306 0.082
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) Smad1 0.0051 0.0554 0.0544
Echinococcus granulosus nmda type glutamate receptor 0.0034 0.032 0.053
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis AGC family protein kinase 0.0033 0.0306 0.082
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0012 0.0031 0.0039
Mycobacterium tuberculosis Probable lipase LipD 0.0043 0.0452 0.1036
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0549 0.4744
Loa Loa (eye worm) hypothetical protein 0.0203 0.261 0.2602
Brugia malayi Protein kinase domain containing protein 0.0033 0.0306 0.0296
Brugia malayi MH1 domain containing protein 0.0051 0.0554 0.0544
Loa Loa (eye worm) hypothetical protein 0.0034 0.032 0.031
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0028 0.003
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0012 0.003 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0012 0.003 0.002
Brugia malayi Metabotropic glutamate receptor precursor. 0.0359 0.4727 0.4721
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0452 0.1836
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0034 0.032 0.031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0028 0.0018
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.091 0.1539
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0028 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0021
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0012 0.003 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0028 0.0018
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0742 0.1252
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.029 0.3788 0.7017
Schistosoma mansoni hypothetical protein 0.0058 0.0652 0.1192
Echinococcus granulosus ubiquitin specific protease 41 0.0012 0.003 0.0034
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0012 0.003 0.0034
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0012 0.003 0.0429
Loa Loa (eye worm) hypothetical protein 0.0043 0.0452 0.0441
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.2641 0.2633
Echinococcus multilocularis mitogen activated protein kinase 0.0062 0.0699 0.1179
Loa Loa (eye worm) hypothetical protein 0.0034 0.032 0.031
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0012 0.003 0.0034
Echinococcus multilocularis beta LACTamase domain containing family member 0.0043 0.0452 0.0755
Echinococcus granulosus nervana 2 0.002 0.0132 0.0207
Trichomonas vaginalis ubiquitin specific protease, putative 0.0012 0.003 0.0081
Schistosoma mansoni tar DNA-binding protein 0.0274 0.3572 0.6617
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0028 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.003 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Toxoplasma gondii ABC1 family protein 0.0043 0.0452 0.1836
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0452 0.1836
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0012 0.003 0.0034
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0012 0.003 0.0034
Brugia malayi Receptor family ligand binding region containing protein 0.0092 0.111 0.11
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0012 0.003 0.0034
Loa Loa (eye worm) hypothetical protein 0.0077 0.091 0.09
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0021 0.0142 0.0225
Brugia malayi MH1 domain containing protein 0.0051 0.0554 0.0544
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0012 0.003 0.0081
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0012 0.0031 0.0039
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Mycobacterium leprae Probable lipase LipE 0.0043 0.0452 0.3324
Echinococcus granulosus serine/threonine protein kinase 0.0023 0.0169 0.0272
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.091 0.5
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0351 0.0632
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0012 0.003 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.003 0.0081
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.091 0.167
Loa Loa (eye worm) RGC/RGC protein kinase 0.0034 0.032 0.031
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Entamoeba histolytica hypothetical protein 0.0034 0.032 0.6787
Schistosoma mansoni hypothetical protein 0.0065 0.0742 0.1358
Onchocerca volvulus Huntingtin homolog 0.0148 0.1866 0.4957
Schistosoma mansoni hypothetical protein 0.0205 0.2633 0.4873
Onchocerca volvulus 0.0012 0.003 0.0005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0012 0.003 0.002
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Loa Loa (eye worm) RGC/RGC protein kinase 0.0034 0.032 0.031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0028 0.0018
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0085 0.0238
Entamoeba histolytica PH domain containing protein kinase, putative 0.0023 0.0169 0.3476
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0062 0.0699 0.2913
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0012 0.003 0.0081
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0012 0.0031 0.0036
Onchocerca volvulus 0.0012 0.0031 0.0009
Trypanosoma cruzi Protein kinase B 0.0023 0.0169 0.0606
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0034 0.032 0.031
Loa Loa (eye worm) hypothetical protein 0.0148 0.1866 0.1857
Brugia malayi mothers against decapentaplegic homolog 3 0.0023 0.0172 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0028 0.0018
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0012 0.003 0.0036
Onchocerca volvulus 0.0012 0.0031 0.0009
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0012 0.003 0.0034
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0082 0.0968 0.1639
Echinococcus granulosus mothers against decapentaplegic 5 0.0051 0.0554 0.093
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.091 1
Trichomonas vaginalis D-aminoacylase, putative 0.0043 0.0452 0.1209
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0012 0.003 0.0034
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0012 0.0031 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0033 0.0306 0.082
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.091 1
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0031 0.0039
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0012 0.003 0.0081
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0452 0.1836
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0012 0.0031 0.0021

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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