Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0046 | 0.8338 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0032 | 0.3982 | 0.4775 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 1 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0032 | 0.3982 | 0.4775 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.4837 | 0.5802 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0032 | 0.3982 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0046 | 0.8338 | 0.8338 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0046 | 0.8338 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0046 | 0.8338 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.8338 | 0.8338 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.4837 | 0.4837 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 1 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0 | 0.5 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0046 | 0.8338 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0 | 0.5 |
Echinococcus granulosus | dna polymerase eta | 0.0046 | 0.8338 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | dna polymerase eta | 0.0046 | 0.8338 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.4837 | 0.4837 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.