Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | histamine h1 receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.001 | 0.0906 | 0.0906 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.4688 | 0.6015 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 0.7362 | 1 |
Echinococcus multilocularis | somatostatin receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | neuropeptide s receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | fmrfamide receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | amine GPCR | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | allatostatin A receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4688 | 0.4688 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | neuropeptide receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | g protein coupled receptor | 0.001 | 0.0906 | 0.0379 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.001 | 0.0906 | 0.0379 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.7362 | 0.7362 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | neuropeptide receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.001 | 0.0906 | 0.0379 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.4403 | 0.5417 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | g-protein coupled receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | sex peptide receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | neuropeptide s receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | neuropeptides capa receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | amine GPCR | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | myosin xvIII | 0.001 | 0.0906 | 0.0906 |
Onchocerca volvulus | 0.0032 | 0.4403 | 1 | |
Echinococcus granulosus | allatostatin A receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.7362 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | opsin-like receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.4688 | 0.6015 |
Schistosoma mansoni | neuropeptide receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.0453 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | orexin receptor type 2 | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0906 | 0.0906 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | neuropeptide Y receptor | 0.001 | 0.0906 | 0.0379 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | neuropeptide receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.001 | 0.0906 | 0.0906 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0005 | 0.0127 | 0.0127 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.001 | 0.0906 | 0.0379 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.8869 | 0.5 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | neuropeptide receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | hypothetical protein | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.001 | 0.0906 | 0.0906 |
Plasmodium falciparum | zinc finger protein, putative | 0.0004 | 0 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | opsin-like receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | opsin-like receptor | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | neuropeptide Y receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.001 | 0.0906 | 0.0379 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.4403 | 0.5417 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.001 | 0.0906 | 0.0906 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0 | 0.5 |
Echinococcus granulosus | sex peptide receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | biogenic amine receptor | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4403 | 0.4403 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.7362 | 0.7362 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | serotonin receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.7362 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.001 | 0.0906 | 0.0379 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.001 | 0.0906 | 0.0379 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0051 | 0.7362 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | g protein coupled receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | amine GPCR | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.4688 | 0.4688 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | fmrfamide receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | g protein coupled receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | g protein coupled receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.001 | 0.0906 | 0.0906 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0651 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0956 | 0.0077 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | biogenic amine receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.7362 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | serotonin receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | fmrfamide receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.7362 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.7362 | 0.7362 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.0453 |
Echinococcus granulosus | orexin receptor type 2 | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | neuropeptide receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | neuropeptides capa receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.001 | 0.0906 | 0.0906 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.001 | 0.0906 | 0.0379 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | g protein coupled receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | g protein coupled receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | neuropeptide receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.001 | 0.0906 | 0.0379 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0936 | 0.0046 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | adenoreceptor | 0.001 | 0.0906 | 0.0906 |
Echinococcus granulosus | neuropeptide receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus granulosus | g-protein coupled receptor | 0.001 | 0.0906 | 0.0379 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.001 | 0.0906 | 0.0379 |
Schistosoma mansoni | amine GPCR | 0.001 | 0.0906 | 0.0906 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.