Detailed information for compound 1473107

Basic information

Technical information
  • TDR Targets ID: 1473107
  • Name: (8S,9S,11S,13S,14S,17R)-17-[(E)-2-chloroethen yl]-11-methoxy-13-methyl-7,8,9,11,12,14,15,16 -octahydro-6H-cyclopenta[a]phenanthrene-3,17- diol
  • MW: 362.89 | Formula: C21H27ClO3
  • H donors: 2 H acceptors: 2 LogP: 3.99 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cl/C=C/[C@]1(O)CC[C@@H]2[C@]1(C)C[C@H](OC)[C@H]1[C@H]2CCc2c1ccc(c2)O
  • InChi: 1S/C21H27ClO3/c1-20-12-18(25-2)19-15-6-4-14(23)11-13(15)3-5-16(19)17(20)7-8-21(20,24)9-10-22/h4,6,9-11,16-19,23-24H,3,5,7-8,12H2,1-2H3/b10-9+/t16-,17-,18-,19+,20-,21+/m0/s1
  • InChiKey: WYSGEJWYPOTZIV-JBCZNIOISA-N  


Substructure search Similarity search

Network

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Synonyms

  • (8S,9S,11S,13S,14S,17R)-17-[(E)-2-chlorovinyl]-11-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Variant SH3 domain containing protein 0.0035 0.002 0.0011
Schistosoma mansoni trans-prenyltransferase 0.0103 0.0311 0.0799
Schistosoma mansoni myosin xvIII 0.0061 0.0132 0.0288
Loa Loa (eye worm) hypothetical protein 0.0833 0.3423 0.7824
Echinococcus granulosus NDR protein kinase 0.0223 0.0822 0.2326
Echinococcus granulosus fmrfamide receptor 0.0061 0.0132 0.0373
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.022 0.0807 0.2283
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0406 0.1148
Echinococcus multilocularis serotonin receptor 0.0061 0.0132 0.0373
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0132 0.0288
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0038 0.0031 0.0088
Echinococcus multilocularis unc 13 (munc13) 0.022 0.0807 0.2283
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0031 0.0088
Schistosoma mansoni opsin-like receptor 0.0061 0.0132 0.0288
Echinococcus granulosus neuropeptide FF receptor 2 0.0061 0.0132 0.0373
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0061 0.0132 0.033
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0132 0.0373
Schistosoma mansoni tyrosine kinase 0.0147 0.0497 0.133
Loa Loa (eye worm) hypothetical protein 0.0833 0.3423 0.7824
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0046 0.0065 0.0183
Entamoeba histolytica cell division protein kinase 2, putative 0.005 0.0085 0.0492
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0261 0.0982 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0061 0.0132 0.0373
Brugia malayi G protein-coupled receptor 0.0061 0.0132 0.033
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0103 0.0311 0.0227
Brugia malayi AKH receptor 0.0061 0.0132 0.033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Echinococcus granulosus cyclin dependent kinase 0.005 0.0085 0.0242
Echinococcus granulosus Diacylglycerol kinase theta 0.0201 0.0726 0.2054
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus granulosus tachykinin peptides receptor 99D 0.0061 0.0132 0.0373
Echinococcus multilocularis protein kinase c eta type 0.0201 0.0726 0.2054
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0061 0.0132 0.0373
Brugia malayi GnHR receptor homolog 0.0061 0.0132 0.033
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0061 0.0132 0.0288
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0261 0.0982 0.0904
Loa Loa (eye worm) hypothetical protein 0.0201 0.0726 0.166
Loa Loa (eye worm) hypothetical protein 0.022 0.0807 0.1844
Schistosoma mansoni protein kinase C mu 0.0201 0.0726 0.1984
Entamoeba histolytica diacylglycerol kinase, putative 0.0201 0.0726 0.4182
Brugia malayi RhoGEF domain containing protein 0.0201 0.0726 0.2019
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0132 0.0301
Echinococcus multilocularis serine threonine protein kinase 0.0599 0.2426 0.6862
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0132 0.0373
Echinococcus multilocularis neuropeptide s receptor 0.0061 0.0132 0.0373
Loa Loa (eye worm) AGC/PKN protein kinase 0.0223 0.0822 0.188
Schistosoma mansoni protein kinase C 0.022 0.0807 0.2214
Onchocerca volvulus 0.058 0.2346 0.6727
Echinococcus multilocularis serine:threonine protein kinase 38 0.0223 0.0822 0.2326
Brugia malayi C1-like domain containing protein 0.0577 0.233 0.6576
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0103 0.0311 0.0227
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0223 0.0822 0.188
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0258 0.097 0.2711
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0061 0.0132 0.0301
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Echinococcus granulosus epidermal growth factor receptor 0.0079 0.0209 0.0592
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0204 0.0742 0.1696
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0223 0.0822 0.188
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0875 0.8809
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0061 0.0132 0.0373
Echinococcus multilocularis G protein coupled receptor 139 0.0061 0.0132 0.0373
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0132 0.0288
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Schistosoma mansoni neuropeptide receptor 0.0061 0.0132 0.0288
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Loa Loa (eye worm) hypothetical protein 0.0213 0.0779 0.178
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0125 0.0406 0.0323
Leishmania major protein kinase A catalytic subunit isoform 1 0.0125 0.0406 0.0323
Brugia malayi hypothetical protein 0.0061 0.0132 0.033
Giardia lamblia Kinase, AGC PKA 0.0125 0.0406 0.3572
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0061 0.0132 0.0288
Brugia malayi Furin-like cysteine rich region family protein 0.0147 0.0497 0.1368
Echinococcus multilocularis serine:threonine protein kinase N2 0.064 0.2599 0.7351
Brugia malayi hypothetical protein 0.0061 0.0132 0.033
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0822 0.2259
Echinococcus granulosus 7TM GPCR rhodopsin 0.0061 0.0132 0.0373
Echinococcus multilocularis g-protein coupled receptor 0.0061 0.0132 0.0373
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0103 0.0311 0.088
Brugia malayi sulfakinin receptor protein 0.0061 0.0132 0.033
Echinococcus granulosus g-protein coupled receptor 0.0061 0.0132 0.0373
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0209 0.0763 0.2159
Loa Loa (eye worm) hypothetical protein 0.0557 0.2248 0.514
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0103 0.0311 0.0227
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0132 0.0288
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0577 0.233 0.5326
Echinococcus granulosus peptide allatostatin:somatostatin 0.0061 0.0132 0.0373
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0201 0.0726 0.166
Schistosoma mansoni biogenic amine receptor 0.0061 0.0132 0.0288
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0103 0.0311 0.5
Loa Loa (eye worm) RasGEF domain-containing protein 0.0201 0.0726 0.166
Echinococcus granulosus hypothetical protein 0.0061 0.0132 0.0373
Echinococcus granulosus somatostatin receptor 0.0061 0.0132 0.0373
Brugia malayi Ras association domain family 1 isoform A 0.0201 0.0726 0.2019
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0763 0.2089
Echinococcus granulosus G protein coupled receptor 139 0.0061 0.0132 0.0373
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.005 0.0085 0.0195
Echinococcus granulosus protein kinase C gamma type 0.0599 0.2426 0.6862
Schistosoma mansoni amine GPCR 0.0061 0.0132 0.0288
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0061 0.0132 0.0373
Echinococcus multilocularis RNA directed DNA polymerase 0.0357 0.1393 0.394
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0132 0.0373
Toxoplasma gondii V-type H(+)-translocating pyrophosphatase VP1 0.2375 1 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0061 0.0132 0.0288
Loa Loa (eye worm) TK/INSR protein kinase 0.0048 0.0074 0.0168
Brugia malayi Protein kinase domain containing protein 0.005 0.0085 0.0198
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0261 0.0982 0.0904
Brugia malayi G-protein coupled receptor 0.0061 0.0132 0.033
Plasmodium falciparum V-type H(+)-translocating pyrophosphatase, putative 0.2375 1 1
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0103 0.0311 0.1791
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0132 0.0288
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0132 0.0373
Loa Loa (eye worm) hypothetical protein 0.0357 0.1393 0.3184
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0132 0.0373
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Loa Loa (eye worm) hypothetical protein 0.0201 0.0726 0.166
Echinococcus granulosus insulin receptor 0.0048 0.0074 0.0208
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.005 0.0085 0.0195
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus granulosus tyrosine protein kinase Src42A 0.0032 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0201 0.0726 0.166
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0132 0.0288
Echinococcus granulosus cyclin dependent kinase 5 0.005 0.0085 0.0242
Entamoeba histolytica protein kinase, putative 0.0046 0.0065 0.0372
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0204 0.0742 0.2028
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0103 0.0311 0.0227
Schistosoma mansoni neuropeptide receptor 0.0061 0.0132 0.0288
Loa Loa (eye worm) hypothetical protein 0.0201 0.0726 0.166
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0132 0.0373
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0132 0.0373
Entamoeba histolytica cell division protein kinase 2, putative 0.005 0.0085 0.0492
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0031 0.0088
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0261 0.0982 0.2778
Echinococcus granulosus neuropeptide receptor 0.0061 0.0132 0.0373
Echinococcus granulosus Protein kinase C brain isozyme 0.08 0.3281 0.9282
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0061 0.0132 0.0288
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0046 0.0065 0.0183
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0822 0.2259
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0117 0.0369 0.1043
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0117 0.0369 0.1043
Onchocerca volvulus 0.0367 0.1437 0.3967
Brugia malayi larval opioid receptor 0.0061 0.0132 0.033
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0223 0.0822 0.2326
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0132 0.0373
Echinococcus multilocularis 0.0045 0.0063 0.0178
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.0202 0.0734 0.2006
Brugia malayi hypothetical protein 0.0061 0.0132 0.033
Onchocerca volvulus 0.022 0.0807 0.2051
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0214 0.0785 0.7807
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Trypanosoma brucei RNA helicase, putative 0.0107 0.0326 0.0243
Schistosoma mansoni hypothetical protein 0.0061 0.0132 0.0288
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0103 0.0311 0.0227
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0223 0.0822 0.2326
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0132 0.0373
Brugia malayi Polyprenyl synthetase family protein 0.0261 0.0982 0.2746
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0032 0.0008 0.0022
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0061 0.0132 0.0373
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0046 0.0065 0.0183
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus granulosus tyrosine protein kinase Src42A 0.0038 0.0031 0.0088
Schistosoma mansoni tyrosine kinase 0.0078 0.0201 0.0486
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0261 0.0982 0.2778
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus granulosus C2 calcium dependent membrane targeting 0.022 0.0807 0.2283
Brugia malayi protein kinase C3,putative 0.0458 0.1824 0.5138
Entamoeba histolytica PH domain containing protein kinase, putative 0.0138 0.0458 0.2641
Entamoeba histolytica hypothetical protein 0.0201 0.0726 0.4182
Trypanosoma brucei Pyrophosphate-energized vacuolar membrane proton pump 1 0.2375 1 1
Echinococcus multilocularis cyclin dependent kinase 1 0.005 0.0085 0.0242
Brugia malayi SRC-1 0.0038 0.0031 0.0044
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0061 0.0132 0.0373
Loa Loa (eye worm) AGC/PKA protein kinase 0.0125 0.0406 0.0927
Schistosoma mansoni biogenic amine (5HT) receptor 0.0061 0.0132 0.0288
Echinococcus granulosus epidermal growth factor receptor 0.0147 0.0497 0.1406
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0604 0.1634
Loa Loa (eye worm) hypothetical protein 0.058 0.2346 0.5362
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Loa Loa (eye worm) hypothetical protein 0.0201 0.0726 0.166
Echinococcus granulosus serotonin receptor 0.0061 0.0132 0.0373
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0132 0.0373
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0204 0.0742 0.2028
Echinococcus multilocularis orexin receptor type 2 0.0061 0.0132 0.0373
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0261 0.0982 0.0904
Loa Loa (eye worm) SRC-1 0.0038 0.0031 0.0071
Echinococcus granulosus tyrosine protein kinase Lyn 0.0046 0.0068 0.0192
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0125 0.0406 0.0323
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0132 0.0288
Schistosoma mansoni atypical protein kinase C 0.0691 0.2817 0.7951
Entamoeba histolytica PH domain containing protein kinase, putative 0.0138 0.0458 0.2641
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0223 0.0822 0.2326
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0038 0.0031 0.0088
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Entamoeba histolytica protein kinase, putative 0.0046 0.0065 0.0372
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0085 0.0155
Echinococcus granulosus neuropeptide receptor 0.0061 0.0132 0.0373
Brugia malayi neuropeptide F receptor 0.0061 0.0132 0.033
Loa Loa (eye worm) polyprenyl synthetase 0.0261 0.0982 0.2245
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0061 0.0132 0.033
Brugia malayi Dopamine receptor protein 2 0.0061 0.0132 0.033
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0103 0.0311 0.0227
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Schistosoma mansoni amine GPCR 0.0061 0.0132 0.0288
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0016 0.0044
Echinococcus granulosus myotubularin protein 13 0.0213 0.0779 0.2203
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0822 0.822
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Brugia malayi ORL1-like opioid receptor 0.0061 0.0132 0.033
Schistosoma mansoni diacylglycerol kinase theta 0.0201 0.0726 0.1984
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Brugia malayi Protein kinase domain containing protein 0.0209 0.0763 0.2124
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0061 0.0132 0.0373
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0046 0.0065 0.0183
Plasmodium vivax V-type H(+)-translocating pyrophosphatase, putative 0.2375 1 1
Trypanosoma brucei rac serine-threonine kinase, putative 0.0236 0.0875 0.0797
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Brugia malayi Variant SH3 domain containing protein 0.0204 0.0742 0.2063
Echinococcus multilocularis N chimaerin 0.0204 0.0742 0.2098
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.005 0.0085 0.0195
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus multilocularis allatostatin A receptor 0.0061 0.0132 0.0373
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0061 0.0132 0.0301
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0384 0.1511 0.3453
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0258 0.097 0.2217
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0822 0.822
Schistosoma mansoni biogenic amine receptor 0.0061 0.0132 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0406 0.1069
Echinococcus granulosus serine:threonine protein kinase N2 0.0425 0.1684 0.4763
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0103 0.0311 0.1791
Leishmania major protein kinase A catalytic subunit isoform 2 0.0125 0.0406 0.0323
Loa Loa (eye worm) hypothetical protein 0.0568 0.2293 0.5241
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0132 0.0373
Echinococcus granulosus tyrosine protein kinase Blk 0.0034 0.0016 0.0044
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Brugia malayi hypothetical protein 0.0061 0.0132 0.033
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0132 0.0373
Entamoeba histolytica protein kinase, putative 0.0223 0.0822 0.4736
Schistosoma mansoni vav2 0.0217 0.0795 0.2179
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0061 0.0132 0.033
Echinococcus multilocularis protein kinase c epsilon type 0.0859 0.3535 1
Loa Loa (eye worm) neuropeptide F receptor 0.0061 0.0132 0.0301
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0061 0.0132 0.0301
Loa Loa (eye worm) polyprenyl synthetase 0.0103 0.0311 0.0711
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0204 0.0742 0.2098
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0125 0.0406 0.1148
Schistosoma mansoni neuropeptide receptor 0.0061 0.0132 0.0288
Echinococcus multilocularis G-protein coupled receptor, putative 0.0061 0.0132 0.0373
Schistosoma mansoni hypothetical protein 0.0107 0.0326 0.0843
Echinococcus granulosus alpha 1A adrenergic receptor 0.0061 0.0132 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.08 0.3281 0.9276
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0103 0.0311 0.5
Echinococcus multilocularis somatostatin receptor 0.0061 0.0132 0.0373
Brugia malayi hypothetical protein 0.0061 0.0132 0.033
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0763 0.2089
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0125 0.0406 0.0323
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0061 0.0132 0.0301
Echinococcus multilocularis Diacylglycerol kinase theta 0.0201 0.0726 0.2054
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.0031 0.0088
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0125 0.0406 0.0323
Leishmania major farnesyl pyrophosphate synthase 0.0261 0.0982 0.0904
Echinococcus granulosus allatostatin A receptor 0.0061 0.0132 0.0373
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0061 0.0132 0.0288
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0125 0.0406 0.0323
Trypanosoma brucei Pyrophosphate-energized vacuolar membrane proton pump 2, putative 0.2375 1 1
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0223 0.0822 0.188
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0103 0.0311 0.088
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus granulosus tyrosine protein kinase Src64B 0.0038 0.0031 0.0088
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0132 0.0288
Echinococcus multilocularis sex peptide receptor 0.0061 0.0132 0.0373
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0103 0.0311 0.0227
Schistosoma mansoni rac gtpase activating protein 0.0201 0.0726 0.1984
Loa Loa (eye worm) TYRA-2 protein 0.0061 0.0132 0.0301
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus multilocularis myotubularin protein 13 0.0213 0.0779 0.2203
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0103 0.0311 0.088
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0132 0.0373
Leishmania major solanesyl-diphosphate synthase, putative 0.0103 0.0311 0.0227
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0132 0.0301
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0223 0.0822 0.2326
Echinococcus granulosus serine:threonine protein kinase N2 0.0223 0.0822 0.2326
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0132 0.0288
Echinococcus granulosus orexin receptor type 2 0.0061 0.0132 0.0373
Brugia malayi Protein kinase c protein 2 0.0585 0.2366 0.6679
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Schistosoma mansoni unc-13 (munc13) 0.022 0.0807 0.2214
Schistosoma mansoni neuropeptide receptor 0.0061 0.0132 0.0288
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0261 0.0982 1
Schistosoma mansoni opsin-like receptor 0.0061 0.0132 0.0288
Brugia malayi p70 ribosomal S6 kinase beta 0.0223 0.0822 0.2292
Brugia malayi Dopamine receptor protein 1 0.0061 0.0132 0.033
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0038 0.0031 0.0088
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0223 0.0822 0.2326
Loa Loa (eye worm) raf kinase 0.0201 0.0726 0.166
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0577 0.233 0.6576
Echinococcus granulosus biogenic amine 5HT receptor 0.0061 0.0132 0.0373
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0125 0.0406 0.0323
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0201 0.0726 0.166
Echinococcus granulosus protein kinase c iota type 0.0672 0.2739 0.7748
Schistosoma mansoni adenoreceptor 0.0061 0.0132 0.0288
Schistosoma mansoni tyrosine kinase 0.0079 0.0209 0.0508
Echinococcus granulosus neuropeptides capa receptor 0.0061 0.0132 0.0373
Echinococcus granulosus sex peptide receptor 0.0061 0.0132 0.0373
Schistosoma mansoni amine GPCR 0.0061 0.0132 0.0288
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0875 0.8809
Entamoeba histolytica diacylglycerol kinase, putative 0.0201 0.0726 0.4182
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0061 0.0132 0.0301
Brugia malayi diacylglycerol kinase 0.0201 0.0726 0.2019
Trypanosoma cruzi Vacuolar proton pyrophosphatase 1, putative 0.2375 1 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Brugia malayi Protein kinase domain containing protein 0.0048 0.0074 0.0165
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Toxoplasma gondii diacylglycerol kinase, putative 0.0201 0.0726 0.0646
Schistosoma mansoni biogenic amine (5HT) receptor 0.0061 0.0132 0.0288
Schistosoma mansoni unc-13 (munc13) 0.022 0.0807 0.2214
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0875 0.8809
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0258 0.097 0.2679
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0132 0.0373
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0261 0.0982 0.0904
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0038 0.0031 0.0088
Brugia malayi neuropeptide F receptor 0.0061 0.0132 0.033
Loa Loa (eye worm) hypothetical protein 0.0125 0.0406 0.0927
Brugia malayi diacylglycerol kinase 0.0201 0.0726 0.2019
Schistosoma mansoni growth hormone secretagogue receptor 0.0061 0.0132 0.0288
Entamoeba histolytica protein kinase, putative 0.0223 0.0822 0.4736
Schistosoma mansoni amine GPCR 0.0061 0.0132 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0859 0.3535 1
Brugia malayi Protein kinase domain containing protein 0.0172 0.0604 0.1671
Loa Loa (eye worm) TK/EGFR protein kinase 0.0147 0.0497 0.1136
Plasmodium vivax vacuolar-type H+ pumping pyrophosphatase, putative 0.2375 1 1
Trypanosoma cruzi polyprenyl synthase, putative 0.0258 0.097 0.0892
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0357 0.1393 0.394
Echinococcus multilocularis Protein kinase C, brain isozyme 0.08 0.3281 0.9282
Loa Loa (eye worm) hypothetical protein 0.0201 0.0726 0.166
Schistosoma mansoni hypothetical protein 0.0061 0.0132 0.0288
Echinococcus granulosus neuropeptide Y receptor 0.0061 0.0132 0.0373
Treponema pallidum octaprenyl-diphosphate synthase 0.0258 0.097 0.5
Brugia malayi RhoGAP domain containing protein 0.0201 0.0726 0.2019
Loa Loa (eye worm) hypothetical protein 0.1033 0.4278 0.978
Echinococcus granulosus tm gpcr rhodopsin 0.0061 0.0132 0.0373
Echinococcus granulosus N chimaerin 0.0204 0.0742 0.2098
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0875 0.8809
Trichomonas vaginalis AGC family protein kinase 0.0125 0.0406 0.3572
Echinococcus granulosus dro:myosuppressin receptor 0.0061 0.0132 0.0373
Brugia malayi Protein kinase domain containing protein 0.0223 0.0822 0.2292
Echinococcus multilocularis dro:myosuppressin receptor 0.0061 0.0132 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0406 0.1069
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0061 0.0132 0.033
Echinococcus granulosus g protein coupled receptor 0.0061 0.0132 0.0373
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0261 0.0982 1
Echinococcus multilocularis neuropeptides capa receptor 0.0061 0.0132 0.0373
Echinococcus granulosus neuropeptide s receptor 0.0061 0.0132 0.0373
Schistosoma mansoni alpha-1 adrenergic receptor 0.0061 0.0132 0.0288
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.0031 0.0088
Leishmania major polyprenyl synthase, putative 0.0258 0.097 0.0892
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0085 0.0155
Echinococcus multilocularis epidermal growth factor receptor 0.0079 0.0209 0.0592
Brugia malayi hypothetical protein 0.0061 0.0132 0.033
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0061 0.0132 0.0288
Echinococcus multilocularis serotonin receptor 0.0061 0.0132 0.0373
Brugia malayi Protein kinase domain containing protein 0.0223 0.0822 0.2292
Brugia malayi hypothetical protein 0.0061 0.0132 0.033
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Brugia malayi G-protein coupled receptor 0.0061 0.0132 0.033
Brugia malayi putative neuropeptide receptor 0.0061 0.0132 0.033
Leishmania major protein kinase A catalytic subunit 0.0125 0.0406 0.0323
Echinococcus multilocularis rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Entamoeba histolytica protein kinase, putative 0.0236 0.0875 0.504
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0103 0.0311 0.1791
Loa Loa (eye worm) AGC/AKT protein kinase 0.0236 0.0875 0.2001
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0079 0.0209 0.0592
Schistosoma mansoni tyrosine kinase 0.0078 0.0201 0.0486
Toxoplasma gondii AGC kinase 0.0223 0.0822 0.0743
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0261 0.0982 0.0904
Entamoeba histolytica PH domain containing protein kinase, putative 0.0437 0.1736 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0132 0.0288
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0132 0.0288
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0125 0.0406 0.0323
Schistosoma mansoni diacylglycerol kinase theta 0.0201 0.0726 0.1984
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0038 0.0031 0.0088
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0258 0.097 0.2743
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0048 0.0074 0.0208
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0875 0.8809
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0061 0.0132 0.0373
Echinococcus multilocularis raf serine:threonine protein kinase 0.0202 0.0734 0.2076
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0035 0.002 0.0045
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0125 0.0406 0.0323
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0376 0.1474 0.337
Echinococcus multilocularis serine:threonine protein kinase N2 0.0223 0.0822 0.2326
Schistosoma mansoni tyrosine kinase 0.0079 0.0209 0.0508
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0061 0.0132 0.0373
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0406 0.1148
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus multilocularis protein kinase c iota type 0.0672 0.2739 0.7748
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.0406 0.1069
Brugia malayi Dopamine receptor 0.0061 0.0132 0.033
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0875 0.8809
Brugia malayi G protein-coupled receptor F59B2.13 0.0061 0.0132 0.033
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0061 0.0132 0.0373
Schistosoma mansoni neuropeptide f receptor 76f 0.0061 0.0132 0.0288
Brugia malayi protein kinase C II. 0.0859 0.3535 1
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0822 0.2259
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Brugia malayi Pleckstrin Homology Domain 0.0213 0.0779 0.2169
Loa Loa (eye worm) AGC/PKA protein kinase 0.0125 0.0406 0.0927
Brugia malayi RhoGAP domain containing protein 0.0204 0.0742 0.2063
Loa Loa (eye worm) hypothetical protein 0.0367 0.1437 0.3285
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus granulosus protein kinase c eta type 0.0201 0.0726 0.2054
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0061 0.0132 0.0373
Schistosoma mansoni opsin-like receptor 0.0061 0.0132 0.0288
Plasmodium falciparum V-type K+-independent H+-translocating inorganic pyrophosphatase 0.2375 1 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0132 0.0288
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Schistosoma mansoni protein kinase C mu 0.0577 0.233 0.6561
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0038 0.0031 0.0088
Brugia malayi Hr1 repeat family protein 0.0223 0.0822 0.2292
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0061 0.0132 0.0288
Loa Loa (eye worm) G-protein coupled receptor 0.0061 0.0132 0.0301
Echinococcus granulosus 7tm_1 domain containing protein 0.0061 0.0132 0.0373
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0132 0.0373
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0406 0.1148
Schistosoma mansoni hypothetical protein 0.0201 0.0726 0.1984
Onchocerca volvulus 0.0568 0.2293 0.6567
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0103 0.0311 0.5
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0061 0.0132 0.0288
Echinococcus granulosus neuropeptide receptor A26 0.0061 0.0132 0.0373
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0125 0.0406 0.0323
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0261 0.0982 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0038 0.0031 0.0088
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.005 0.0085 0.0242
Echinococcus multilocularis epidermal growth factor receptor 0.0147 0.0497 0.1406
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0204 0.0742 0.2098
Loa Loa (eye worm) AGC/NDR protein kinase 0.0223 0.0822 0.188
Echinococcus multilocularis fmrfamide receptor 0.0061 0.0132 0.0373
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus granulosus biogenic amine 5HT receptor 0.0061 0.0132 0.0373
Echinococcus multilocularis neuropeptide receptor A26 0.0061 0.0132 0.0373
Entamoeba histolytica protein kinase, putative 0.0236 0.0875 0.504
Echinococcus multilocularis cyclin dependent kinase 0.005 0.0085 0.0242
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0261 0.0982 0.2714
Echinococcus multilocularis cyclin dependent kinase 1 0.005 0.0085 0.0242
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0061 0.0132 0.033
Schistosoma mansoni serine/threonine kinase 0.0223 0.0822 0.2259
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0103 0.0311 0.088
Echinococcus granulosus raf serine:threonine protein kinase 0.0202 0.0734 0.2076
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0261 0.0982 0.0904
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0132 0.0288
Echinococcus multilocularis tyrosine protein kinase Blk 0.0034 0.0016 0.0044
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0476 0.1902 0.4348
Echinococcus granulosus Rac GTPase activating protein 1 0.0201 0.0726 0.2054
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0859 0.3535 0.8081
Brugia malayi hypothetical protein 0.0061 0.0132 0.033
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0209 0.0763 0.2159
Echinococcus granulosus protein kinase c epsilon type 0.0859 0.3535 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0048 0.0111
Onchocerca volvulus 0.0833 0.3423 1
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0125 0.0406 0.1148
Echinococcus multilocularis neuropeptide FF receptor 2 0.0061 0.0132 0.0373
Brugia malayi putative neuropeptide receptor NPR1 0.0061 0.0132 0.033
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0034 0.0016 0.0044
Schistosoma mansoni tyrosine kinase 0.0048 0.0074 0.0122
Schistosoma mansoni glutathione synthetase 0.0103 0.0311 0.0799
Echinococcus granulosus tyrosine protein kinase Fyn 0.0038 0.0031 0.0088
Schistosoma mansoni tyrosine kinase 0.0078 0.0201 0.0486
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Echinococcus multilocularis neuropeptide Y receptor 0.0061 0.0132 0.0373
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0875 0.8809
Brugia malayi Polyprenyl synthetase family protein 0.0103 0.0311 0.0839
Schistosoma mansoni histamine h1 receptor 0.0061 0.0132 0.0288
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0061 0.0132 0.0373
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0103 0.0311 0.5
Echinococcus granulosus RNA directed DNA polymerase 0.0357 0.1393 0.394
Echinococcus multilocularis Rac GTPase activating protein 1 0.0201 0.0726 0.2054
Echinococcus granulosus unc 13 munc13 0.022 0.0807 0.2283
Echinococcus multilocularis cyclin dependent kinase 5 0.005 0.0085 0.0242
Brugia malayi Tachykinin-like peptides receptor 99D 0.0061 0.0132 0.033
Brugia malayi cell division control protein 2 homolog 0.005 0.0085 0.0198
Echinococcus multilocularis neuropeptide receptor 0.0061 0.0132 0.0373
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0258 0.097 0.2743
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0223 0.0822 0.188
Brugia malayi Serotonin receptor 0.0061 0.0132 0.033
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Trichomonas vaginalis AGC family protein kinase 0.0236 0.0875 0.8809
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0223 0.0822 0.2326
Echinococcus multilocularis tyrosine protein kinase Srms 0.0034 0.0016 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0822 0.2259
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0125 0.0406 0.0323
Toxoplasma gondii AGC kinase 0.0125 0.0406 0.0323
Brugia malayi Melatonin receptor type 1A 0.0061 0.0132 0.033
Loa Loa (eye worm) melatonin receptor type 1A 0.0061 0.0132 0.0301
Loa Loa (eye worm) hypothetical protein 0.0061 0.0132 0.0301
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0172 0.0604 0.138
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0125 0.0406 0.1148
Echinococcus granulosus g protein coupled receptor 0.0061 0.0132 0.0373
Brugia malayi follicle stimulating hormone receptor 0.0061 0.0132 0.033
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0038 0.0031 0.0088
Loa Loa (eye worm) hypothetical protein 0.1056 0.4375 1
Echinococcus granulosus tyrosine kinase 0.0034 0.0016 0.0044
Schistosoma mansoni neuropeptide F-like receptor 0.0061 0.0132 0.0288
Giardia lamblia Farnesyl diphosphate synthase 0.0261 0.0982 1
Schistosoma mansoni amine GPCR 0.0061 0.0132 0.0288
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0261 0.0982 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0061 0.0132 0.0373
Brugia malayi hypothetical protein 0.0061 0.0132 0.033
Trichomonas vaginalis AGC family protein kinase 0.0223 0.0822 0.822
Schistosoma mansoni serine/threonine protein kinase 0.08 0.3281 0.9276
Echinococcus multilocularis insulin receptor 0.0048 0.0074 0.0208
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0125 0.0406 0.1108
Toxoplasma gondii AGC kinase 0.0125 0.0406 0.0323
Brugia malayi RE15519p 0.0061 0.0132 0.033
Schistosoma mansoni hypothetical protein 0.0061 0.0132 0.0288
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0048 0.0074 0.0208
Echinococcus multilocularis g protein coupled receptor 0.0061 0.0132 0.0373
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0038 0.0031 0.0088
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0061 0.0132 0.0373
Echinococcus granulosus cyclin dependent kinase 1 0.005 0.0085 0.0242
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0061 0.0132 0.0288
Loa Loa (eye worm) TK protein kinase 0.0034 0.0016 0.0036
Loa Loa (eye worm) hypothetical protein 0.0833 0.3423 0.7824
Schistosoma mansoni hypothetical protein 0.0061 0.0132 0.0288
Trypanosoma cruzi polyprenyl synthase, putative 0.0258 0.097 0.0892
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0061 0.0132 0.0373
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0261 0.0982 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0061 0.0132 0.0288
Loa Loa (eye worm) hypothetical protein 0.0367 0.1437 0.3285
Trypanosoma cruzi vacuolar-type proton translocating pyrophosphatase 1 0.2375 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0061 0.0132 0.0373
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0125 0.0406 0.1148
Brugia malayi Protein kinase domain containing protein 0.0236 0.0875 0.2442
Schistosoma mansoni tyrosine kinase 0.0048 0.0074 0.0122
Schistosoma mansoni biogenic amine receptor 0.0061 0.0132 0.0288
Echinococcus granulosus g protein coupled receptor 0.0061 0.0132 0.0373
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0061 0.0132 0.0288
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0065 0.0096
Brugia malayi Serotonin receptor 0.0061 0.0132 0.033
Brugia malayi hypothetical protein 0.0061 0.0132 0.033

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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