Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.1755 | 0.7143 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.1112 | 0 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.1112 | 0 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.1755 | 0.7143 | 0.5 |
Treponema pallidum | methionine aminopeptidase (map) | 0.1112 | 0 | 0.5 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.1755 | 0.7143 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.1112 | 0 | 0.5 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.1755 | 0.7143 | 1 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.1755 | 0.7143 | 0.5 |
Schistosoma mansoni | microtubule-associated protein tau | 0.2013 | 1 | 1 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.1755 | 0.7143 | 0.5 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.1755 | 0.7143 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.1755 | 0.7143 | 0.7143 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.1112 | 0 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.1755 | 0.7143 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.1112 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.1112 | 0 | 0.5 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.1755 | 0.7143 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.1112 | 0 | 0.5 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.2013 | 1 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.1755 | 0.7143 | 1 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.1755 | 0.7143 | 0.5 |
Chlamydia trachomatis | methionine aminopeptidase | 0.1112 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.