Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.049 | 0.112 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.049 | 0.112 | 0.112 |
Echinococcus multilocularis | acetylcholinesterase | 0.29 | 1 | 1 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0364 | 0.0655 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.049 | 0.112 | 0.112 |
Brugia malayi | Carboxylesterase family protein | 0.29 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.049 | 0.112 | 0.112 |
Echinococcus multilocularis | carboxylesterase 5A | 0.29 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.049 | 0.112 | 0.112 |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.0655 | 0.0655 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.049 | 0.112 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.29 | 1 | 1 |
Onchocerca volvulus | 0.049 | 0.112 | 0.5 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.049 | 0.112 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.29 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.29 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.29 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.049 | 0.112 | 0.112 |
Echinococcus granulosus | carboxylesterase 5A | 0.29 | 1 | 1 |
Onchocerca volvulus | 0.049 | 0.112 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.049 | 0.112 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.049 | 0.112 | 0.0498 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.049 | 0.112 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.29 | 1 | 1 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0364 | 0.0655 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.049 | 0.112 | 0.112 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.049 | 0.112 | 0.5 |
Brugia malayi | hypothetical protein | 0.049 | 0.112 | 0.0498 |
Brugia malayi | Carboxylesterase family protein | 0.049 | 0.112 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.29 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.049 | 0.112 | 0.112 |
Brugia malayi | Carboxylesterase family protein | 0.049 | 0.112 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.049 | 0.112 | 0.112 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.049 | 0.112 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.29 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.049 | 0.112 | 0.112 |
Onchocerca volvulus | 0.049 | 0.112 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.049 | 0.112 | 0.0498 |
Onchocerca volvulus | 0.049 | 0.112 | 0.5 | |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0364 | 0.0655 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.29 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.