Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0423 | 0.7224 | 0.7224 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0556 | 1 | 1 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0423 | 0.7224 | 0.7224 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0556 | 1 | 1 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0556 | 1 | 1 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0556 | 1 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0423 | 0.7224 | 0.7224 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0556 | 1 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0081 | 0.007 | 0.007 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0211 | 0.2787 | 0.2787 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0081 | 0.007 | 0.007 |
Trypanosoma brucei | prolyl endopeptidase | 0.0163 | 0.1787 | 0.1787 |
Toxoplasma gondii | prolyl endopeptidase | 0.0163 | 0.1787 | 0.1787 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0163 | 0.1787 | 0.1787 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0556 | 1 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0556 | 1 | 1 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0163 | 0.1787 | 0.1787 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0211 | 0.2787 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0081 | 0.007 | 0.007 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0423 | 0.7224 | 0.7224 |
Mycobacterium ulcerans | proteasome PrcB | 0.0556 | 1 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0081 | 0.007 | 0.007 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0556 | 1 | 1 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0211 | 0.2787 | 0.2787 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0556 | 1 | 1 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0556 | 1 | 1 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0556 | 1 | 1 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0163 | 0.1787 | 0.6412 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.0078 | 0 | 0.5 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0081 | 0.007 | 0.007 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0081 | 0.007 | 0.007 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0556 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.1787 | 0.1787 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0132 | 0.1138 | 0.1138 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0211 | 0.2787 | 0.2787 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0423 | 0.7224 | 0.7224 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0556 | 1 | 1 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0423 | 0.7224 | 0.7224 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0423 | 0.7224 | 0.7224 |
Brugia malayi | proteasome subunit beta type 1 | 0.0423 | 0.7224 | 0.7224 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0163 | 0.1787 | 0.1787 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0423 | 0.7224 | 0.7224 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0081 | 0.007 | 0.007 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0081 | 0.007 | 0.007 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0423 | 0.7224 | 0.7224 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0423 | 0.7224 | 0.7224 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0211 | 0.2787 | 0.2787 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0081 | 0.007 | 0.007 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0423 | 0.7224 | 0.7224 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0556 | 1 | 1 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0423 | 0.7224 | 0.7224 |
Echinococcus granulosus | prolyl endopeptidase | 0.0163 | 0.1787 | 0.1787 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0556 | 1 | 1 |
Echinococcus granulosus | proteasome prosome macropain | 0.0556 | 1 | 1 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0163 | 0.1787 | 0.1787 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0423 | 0.7224 | 0.7224 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0211 | 0.2787 | 0.2787 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0081 | 0.007 | 0.007 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0163 | 0.1787 | 0.1787 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0423 | 0.7224 | 0.7224 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0163 | 0.1787 | 0.1787 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.