Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0406 | 1 | 1 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0187 | 0.3578 | 0.3458 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0187 | 0.3578 | 0.3458 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0072 | 0.0183 | 0.0183 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0406 | 1 | 1 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0406 | 1 | 1 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0406 | 1 | 1 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0406 | 1 | 1 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0145 | 0.2328 | 0.2328 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0406 | 1 | 1 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0406 | 1 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0406 | 1 | 1 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0072 | 0.0183 | 0.0183 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0072 | 0.0183 | 0.0183 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0309 | 0.7149 | 0.7149 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0309 | 0.7149 | 0.6284 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0118 | 0.1517 | 0.1517 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0187 | 0.3578 | 0.1629 |
Echinococcus granulosus | proteasome prosome macropain | 0.0406 | 1 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0309 | 0.7149 | 0.7096 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0309 | 0.7149 | 0.7149 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0406 | 1 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.0145 | 0.2328 | 0.2185 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0406 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0145 | 0.2328 | 0.2185 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0406 | 1 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0406 | 1 | 1 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0309 | 0.7149 | 0.7149 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0145 | 0.2328 | 0.2185 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0072 | 0.0183 | 0.0183 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0309 | 0.7149 | 0.7096 |
Echinococcus granulosus | prolyl endopeptidase | 0.0145 | 0.2328 | 0.2185 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0145 | 0.2328 | 0.2185 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0406 | 1 | 1 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0406 | 1 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0187 | 0.3578 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0072 | 0.0183 | 0.0183 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0187 | 0.3578 | 0.3458 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0145 | 0.2328 | 0.2185 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0406 | 1 | 1 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0309 | 0.7149 | 0.7149 |
Trypanosoma brucei | prolyl endopeptidase | 0.0145 | 0.2328 | 0.2328 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0187 | 0.3578 | 0.3458 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0145 | 0.2328 | 0.2328 |
Mycobacterium ulcerans | proteasome PrcB | 0.0406 | 1 | 1 |
Brugia malayi | proteasome subunit beta type 1 | 0.0309 | 0.7149 | 0.7096 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0309 | 0.7149 | 0.7096 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0309 | 0.7149 | 0.7096 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.