Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.3146 | 0.567 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.3146 | 0.567 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0069 | 0.3146 | 0.291 |
Trichomonas vaginalis | beta-hexosaminidase B, putative | 0.0058 | 0.224 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.0333 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0069 | 0.3146 | 0.291 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0147 | 1 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0333 | 0.5 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0058 | 0.224 | 1 |
Schistosoma mansoni | beta-hexosaminidase B | 0.0093 | 0.5293 | 1 |
Echinococcus multilocularis | beta hexosaminidase subunit alpha | 0.0058 | 0.224 | 0.1973 |
Loa Loa (eye worm) | TAR-binding protein | 0.0069 | 0.3146 | 0.291 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.0333 | 0.5 |
Echinococcus multilocularis | beta hexosaminidase subunit beta | 0.0093 | 0.5293 | 0.5131 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0333 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.0333 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0069 | 0.3146 | 0.291 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0333 | 0.5 |
Echinococcus multilocularis | muscleblind protein | 0.0147 | 1 | 1 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, beta subunit | 0.0093 | 0.5293 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0069 | 0.3146 | 0.291 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.0333 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 1 | 1 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0 | 0.5 |
Brugia malayi | RNA binding protein | 0.0069 | 0.3146 | 0.291 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, putative | 0.0093 | 0.5293 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.3146 | 0.567 |
Brugia malayi | TAR-binding protein | 0.0069 | 0.3146 | 0.291 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, putative | 0.0093 | 0.5293 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.3146 | 0.567 |
Schistosoma mansoni | tar DNA-binding protein | 0.0069 | 0.3146 | 0.567 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0058 | 0.224 | 1 |
Echinococcus granulosus | beta hexosaminidase subunit beta | 0.0093 | 0.5293 | 0.5131 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, alpha subunit | 0.0093 | 0.5293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 1 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 20 | 0.0093 | 0.5293 | 0.5131 |
Echinococcus granulosus | muscleblind protein | 0.0147 | 1 | 1 |
Brugia malayi | Glycosyl hydrolase family 20, catalytic domain containing protein | 0.0093 | 0.5293 | 0.5131 |
Echinococcus granulosus | beta hexosaminidase subunit alpha | 0.0058 | 0.224 | 0.1973 |
Schistosoma mansoni | beta-hexosaminidase B | 0.0093 | 0.5293 | 1 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0058 | 0.224 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0069 | 0.3146 | 0.291 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.